## Mon Feb 16 08:44:18 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/CSH2_bin.11.fa -m mmseqs --output CSH2_bin.11 --output_dir /data/result/bins/wyx/eggqs50+/CSH2_bin.11 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CSH2_k127_1008337_2	269798.CHU_0278	9.999e-16	85.0	28M10@1|root,2ZAFW@2|Bacteria,4NIF8@976|Bacteroidetes,47KHS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
CSH2_k127_1008337_1	762903.Pedsa_0401	7.762e-46	173.0	COG2246@1|root,COG2246@2|Bacteria,4NSQN@976|Bacteroidetes,1ITAX@117747|Sphingobacteriia	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CSH2_k127_1008337_0	700598.Niako_2106	6.911e-83	284.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CSH2_k127_1008338_0	1237149.C900_00152	3.653e-39	150.0	COG0454@1|root,COG0456@2|Bacteria,4NUI2@976|Bacteroidetes,47T49@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_101532_0	925409.KI911562_gene1188	3.731e-99	333.0	COG0741@1|root,COG0741@2|Bacteria,4NEKW@976|Bacteroidetes,1IRNH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CSH2_k127_1015439_1	700598.Niako_6665	1.901e-18	86.0	28NPZ@1|root,2ZBPQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CSH2_k127_1015439_0	700598.Niako_5784	3.547e-56	208.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1IS1E@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1017923_0	1239962.C943_03564	1.97e-219	687.0	COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,47XBR@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CSH2_k127_1017923_1	1122605.KB893625_gene1849	2.916e-37	141.0	COG0761@1|root,COG0761@2|Bacteria	2|Bacteria	IM	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
CSH2_k127_1018872_0	925409.KI911562_gene1392	1.544e-145	471.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_1025799_0	1123248.KB893314_gene3640	1.402e-32	126.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CSH2_k127_1025799_1	1123248.KB893326_gene1410	5.337e-26	117.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K02014,ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000,ko02042	1.B.14	-	-	Alginate_lyase2,CBM_6,CarbopepD_reg_2,F5_F8_type_C,Plug,Thiol_cytolys_C,Thiol_cytolysin,TonB_dep_Rec
CSH2_k127_1026137_0	742725.HMPREF9450_02183	1.116e-191	607.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,22U9Y@171550|Rikenellaceae	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CSH2_k127_1028510_2	1267211.KI669560_gene1918	2.054e-17	85.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CSH2_k127_1028510_1	1122176.KB903542_gene389	3.562e-58	207.0	COG1437@1|root,COG1437@2|Bacteria,4NQQK@976|Bacteroidetes	976|Bacteroidetes	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
CSH2_k127_1028510_0	700598.Niako_5054	2.004e-156	497.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1IPZ7@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CSH2_k127_1033515_1	1120965.AUBV01000005_gene1873	1.552e-07	59.0	2ECP6@1|root,336KZ@2|Bacteria,4NVKQ@976|Bacteroidetes,47SB1@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4843)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4843
CSH2_k127_1033515_0	1089547.KB913013_gene3842	3.811e-118	398.0	COG2913@1|root,COG2913@2|Bacteria,4PM6E@976|Bacteroidetes,47YM0@768503|Cytophagia	976|Bacteroidetes	J	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_1035197_0	700598.Niako_6681	6.405e-61	215.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,1IXAV@117747|Sphingobacteriia	976|Bacteroidetes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
CSH2_k127_1035197_1	1356852.N008_16340	3.952e-38	148.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,47NVA@768503|Cytophagia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CSH2_k127_1038911_1	1123248.KB893317_gene4376	2.085e-20	98.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes	976|Bacteroidetes	D	Cell division protein FtsX	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CSH2_k127_1038911_0	1267211.KI669560_gene2785	2.09e-221	691.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
CSH2_k127_1041760_1	700598.Niako_4475	1.197e-56	200.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1IPEN@117747|Sphingobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CSH2_k127_1041760_0	1550091.JROE01000007_gene2724	8.389e-66	229.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1IRXF@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CSH2_k127_1041760_2	1086011.HJ01_02925	3.504e-08	59.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia,2NSRP@237|Flavobacterium	976|Bacteroidetes	E	aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_1049349_1	929556.Solca_4167	7.646e-97	319.0	COG1011@1|root,COG1011@2|Bacteria,4NF0Y@976|Bacteroidetes,1IRE7@117747|Sphingobacteriia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
CSH2_k127_1049349_0	1123248.KB893315_gene3004	8.2e-100	331.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1IR1T@117747|Sphingobacteriia	976|Bacteroidetes	CP	ABC-type Na efflux pump, permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CSH2_k127_1055540_0	925409.KI911562_gene650	2.505e-32	130.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1IS3Y@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-superfamily hydrolase subfamily IA, variant 3	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
CSH2_k127_1066088_2	1040983.AXAE01000038_gene2562	5.154e-58	205.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2U61A@28211|Alphaproteobacteria,43PGH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CSH2_k127_1066088_1	1144313.PMI10_02566	2.477e-65	227.0	COG4675@1|root,COG4675@2|Bacteria,4NQJR@976|Bacteroidetes,1I31T@117743|Flavobacteriia,2NVVQ@237|Flavobacterium	976|Bacteroidetes	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CSH2_k127_1066088_0	1449076.JOOE01000004_gene231	5.06e-73	250.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria,2K5XG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CSH2_k127_1066088_3	760192.Halhy_5167	2.995e-14	76.0	COG0454@1|root,COG0456@2|Bacteria,4NQT7@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CSH2_k127_106899_1	1237149.C900_01451	1.28e-58	209.0	COG1943@1|root,COG1943@2|Bacteria,4NJZI@976|Bacteroidetes,47PW0@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CSH2_k127_106899_0	643867.Ftrac_0098	3.769e-91	303.0	COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,47P29@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CSH2_k127_107226_1	1379270.AUXF01000001_gene2369	4.028e-33	134.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CSH2_k127_107226_0	485918.Cpin_1599	6.005e-36	144.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1IPNA@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
CSH2_k127_1079307_0	1123248.KB893330_gene392	8.343e-143	457.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1IX1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CSH2_k127_1079307_1	700598.Niako_0331	1.775e-41	160.0	COG0448@1|root,COG0448@2|Bacteria,4PKFG@976|Bacteroidetes,1IPMM@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
CSH2_k127_109360_0	700598.Niako_6365	5.625e-71	252.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,1IPER@117747|Sphingobacteriia	976|Bacteroidetes	S	FUSC-like inner membrane protein yccS	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
CSH2_k127_1097040_0	1267211.KI669560_gene2032	2.106e-134	433.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1IRKN@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CSH2_k127_109875_0	700598.Niako_4693	8.005e-88	307.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1IU7A@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_1103997_0	1267211.KI669560_gene2060	1.272e-93	314.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IV0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
CSH2_k127_1103997_1	925409.KI911562_gene2809	5.778e-62	222.0	COG2849@1|root,COG2849@2|Bacteria,4NZNQ@976|Bacteroidetes	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CSH2_k127_1103997_2	1131812.JQMS01000001_gene2835	2.701e-12	67.0	COG0627@1|root,COG0627@2|Bacteria,4NE7D@976|Bacteroidetes,1HYRB@117743|Flavobacteriia,2NT0U@237|Flavobacterium	976|Bacteroidetes	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CSH2_k127_1105266_2	1123248.KB893385_gene4772	6.257e-23	102.0	28N4A@1|root,2ZB9T@2|Bacteria,4NKZG@976|Bacteroidetes	976|Bacteroidetes	S	COG NOG26965 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CSH2_k127_1105266_1	700598.Niako_7309	1.953e-24	111.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	VP2042	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	OMP_b-brl,OMP_b-brl_2
CSH2_k127_1105266_0	700598.Niako_7310	2.306e-71	246.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1ISYC@117747|Sphingobacteriia	976|Bacteroidetes	K	acr, cog1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CSH2_k127_1105266_3	925409.KI911562_gene116	4.804e-07	57.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,1J0U6@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CSH2_k127_1106960_0	1123248.KB893381_gene1073	1.205e-109	365.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1INMF@117747|Sphingobacteriia	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CSH2_k127_1108184_0	452637.Oter_3986	6.634e-45	164.0	COG0451@1|root,COG0451@2|Bacteria,46TDU@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
CSH2_k127_1115668_0	925409.KI911562_gene2316	5.379e-216	675.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CSH2_k127_1116815_1	1267211.KI669560_gene625	1.776e-84	293.0	COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1INQI@117747|Sphingobacteriia	976|Bacteroidetes	G	3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
CSH2_k127_1116815_0	1267211.KI669560_gene2336	2.514e-317	975.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1INW0@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CSH2_k127_1120123_0	485918.Cpin_4706	6.49e-153	492.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1IV69@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CSH2_k127_1120123_1	485918.Cpin_4707	1.108e-68	239.0	COG0438@1|root,COG0438@2|Bacteria,4NSC6@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_1121962_0	700598.Niako_0512	4.649e-130	426.0	COG5000@1|root,COG5000@2|Bacteria,4PKJN@976|Bacteroidetes,1IQ9K@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CSH2_k127_1121962_4	1500281.JQKZ01000015_gene2145	1.151e-10	65.0	2AAAU@1|root,30ZKF@2|Bacteria,4PDWW@976|Bacteroidetes,1IEA8@117743|Flavobacteriia,3ZT19@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1121962_1	1094466.KQS_09855	4.955e-27	111.0	COG2827@1|root,COG2827@2|Bacteria,4NUKY@976|Bacteroidetes,1II52@117743|Flavobacteriia,2NXVP@237|Flavobacterium	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CSH2_k127_1121962_2	1168034.FH5T_06695	2.684e-14	73.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,2FM5E@200643|Bacteroidia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CSH2_k127_1125236_0	760192.Halhy_4638	2.293e-266	835.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IRCX@117747|Sphingobacteriia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CSH2_k127_1126336_1	1267211.KI669560_gene747	1.297e-19	89.0	2DBS0@1|root,2ZANT@2|Bacteria,4NQP3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1126336_0	1123248.KB893359_gene2106	2.535e-174	550.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CSH2_k127_1141023_1	1123277.KB893206_gene3378	5.813e-75	257.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CSH2_k127_1141023_0	925409.KI911562_gene1113	1.354e-97	327.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1IP8N@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CSH2_k127_1141023_2	86106.I862_01855	3.781e-05	51.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
CSH2_k127_1144523_0	468059.AUHA01000005_gene2463	5.058e-84	284.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1INW1@117747|Sphingobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CSH2_k127_1159046_0	1123248.KB893314_gene3577	3.375e-108	363.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
CSH2_k127_1177160_0	700598.Niako_6981	1.042e-97	331.0	COG0369@1|root,COG0369@2|Bacteria,4NHR8@976|Bacteroidetes,1IP37@117747|Sphingobacteriia	976|Bacteroidetes	P	Flavodoxin	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1,PepSY_TM
CSH2_k127_1178279_1	929713.NIASO_06770	6.159e-78	261.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CSH2_k127_1178279_0	1267211.KI669560_gene1418	5.679e-101	335.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1IRFD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CSH2_k127_1178279_3	925409.KI911562_gene2661	1.427e-05	48.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CSH2_k127_1178890_1	1123248.KB893329_gene4475	0.0003061	43.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CSH2_k127_1178890_0	1123248.KB893314_gene3282	6.809e-123	398.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IPZG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CSH2_k127_118220_1	1492737.FEM08_31090	1.555e-44	162.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ83@117743|Flavobacteriia,2P00V@237|Flavobacterium	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_118220_0	700598.Niako_4469	2.984e-143	464.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes	976|Bacteroidetes	V	transport, permease protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CSH2_k127_1182595_0	761193.Runsl_1070	2.882e-295	920.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_1186972_0	1123278.KB893544_gene4837	1.385e-96	320.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CSH2_k127_1186972_1	1123248.KB893345_gene38	4.744e-25	120.0	2DTG8@1|root,33K7P@2|Bacteria,4NYYK@976|Bacteroidetes,1IUD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1187513_0	1123248.KB893317_gene4263	3.53e-56	201.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CSH2_k127_1187513_1	880073.Calab_0277	3.007e-44	167.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
CSH2_k127_119168_1	700598.Niako_0384	2.029e-29	129.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
CSH2_k127_119168_0	925409.KI911562_gene1946	2.778e-57	207.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1IRH3@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
CSH2_k127_1196286_1	760192.Halhy_3896	7.284e-40	154.0	COG0454@1|root,COG0456@2|Bacteria,4P67I@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_1196286_0	1250232.JQNJ01000001_gene3869	2.17e-47	175.0	COG0346@1|root,COG0346@2|Bacteria,4NQQA@976|Bacteroidetes,1I3V6@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	4.4.1.5	ko:K01759,ko:K03827	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_3,Glyoxalase,Glyoxalase_4
CSH2_k127_1196286_2	1124780.ANNU01000076_gene803	8.595e-40	152.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia	976|Bacteroidetes	K	Cold shock protein domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
CSH2_k127_1200697_0	1123248.KB893348_gene93	1.847e-128	428.0	COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,1IPNG@117747|Sphingobacteriia	976|Bacteroidetes	M	export protein	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
CSH2_k127_1206378_0	925409.KI911562_gene582	4.066e-111	361.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CSH2_k127_1206378_1	1123248.KB893348_gene212	4.543e-48	175.0	COG3637@1|root,COG3637@2|Bacteria,4NNPF@976|Bacteroidetes,1ISTC@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CSH2_k127_1219808_2	1267211.KI669560_gene1798	2.557e-47	171.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,HAD
CSH2_k127_1219808_0	1270196.JCKI01000005_gene2928	1.235e-78	269.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1IR1A@117747|Sphingobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CSH2_k127_1219808_1	700598.Niako_7017	1.871e-54	199.0	COG0664@1|root,COG0664@2|Bacteria,4NQ1A@976|Bacteroidetes,1IY7M@117747|Sphingobacteriia	976|Bacteroidetes	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CSH2_k127_1219808_3	925409.KI911562_gene3036	1.734e-09	58.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_1221839_0	1267211.KI669560_gene518	5.005e-183	578.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CSH2_k127_1224052_0	1229172.JQFA01000004_gene1496	5.635e-136	449.0	COG4320@1|root,COG4320@2|Bacteria,1G0BG@1117|Cyanobacteria,1H91M@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
CSH2_k127_1224052_1	1267211.KI669560_gene1004	2.985e-73	256.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_1224279_0	927658.AJUM01000022_gene1112	0.0	1320.0	COG3459@1|root,COG3459@2|Bacteria,4NIVN@976|Bacteroidetes,2FQ10@200643|Bacteroidia,3XJF8@558415|Marinilabiliaceae	976|Bacteroidetes	G	Putative carbohydrate binding domain	cepA	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
CSH2_k127_1224279_1	927658.AJUM01000022_gene1111	4.772e-166	537.0	COG3291@1|root,COG3291@2|Bacteria,4PKMJ@976|Bacteroidetes,2G0FM@200643|Bacteroidia	976|Bacteroidetes	G	Cellulase N-terminal ig-like domain	-	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
CSH2_k127_1224526_1	1166018.FAES_0176	2.819e-35	138.0	COG1524@1|root,COG1524@2|Bacteria,4NFRQ@976|Bacteroidetes,47JI2@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CSH2_k127_1224526_0	925409.KI911562_gene418	2.725e-102	344.0	COG2602@1|root,COG2602@2|Bacteria,4NH11@976|Bacteroidetes,1IYF8@117747|Sphingobacteriia	976|Bacteroidetes	V	Penicillin binding protein transpeptidase domain	-	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
CSH2_k127_1224526_2	592029.DDD_0451	4.542e-34	138.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
CSH2_k127_1230384_0	314278.NB231_01773	0.0	1256.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1WWMT@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_1230672_0	700598.Niako_5091	2.869e-157	518.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_1231654_1	700598.Niako_0109	2.577e-78	263.0	COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1IPJB@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CSH2_k127_1231654_0	925409.KI911562_gene1982	1.25e-107	353.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1IP8F@117747|Sphingobacteriia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CSH2_k127_1232969_0	760192.Halhy_0875	1.139e-125	411.0	COG0151@1|root,COG0151@2|Bacteria,4P144@976|Bacteroidetes	976|Bacteroidetes	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1237226_0	1267211.KI669560_gene2540	4.722e-100	327.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CSH2_k127_1246292_0	504472.Slin_6200	4.751e-124	405.0	COG1524@1|root,COG1524@2|Bacteria,4NFRQ@976|Bacteroidetes,47JI2@768503|Cytophagia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CSH2_k127_1263512_0	925409.KI911562_gene1391	8.305e-124	405.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CSH2_k127_1264993_1	1123248.KB893359_gene2053	1.515e-32	131.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CSH2_k127_1264993_0	1123248.KB893359_gene2052	2.17e-101	341.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
CSH2_k127_1273036_0	485918.Cpin_1514	3.619e-92	306.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1IQH3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CSH2_k127_1273036_1	1121129.KB903360_gene3158	8.536e-57	204.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,2FPNI@200643|Bacteroidia,22XA0@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CSH2_k127_1273736_0	925409.KI911562_gene1047	6.813e-102	342.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1INY1@117747|Sphingobacteriia	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CSH2_k127_1287227_1	1123248.KB893314_gene3482	7.557e-48	182.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VanZ
CSH2_k127_1287227_0	1122176.KB903558_gene4192	9.257e-58	204.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1IPY6@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CSH2_k127_1287540_0	929556.Solca_3213	9.711e-117	387.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IR4R@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 39	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
CSH2_k127_1288648_0	929562.Emtol_3518	1.591e-172	557.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47MZ7@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CSH2_k127_1293652_1	1166018.FAES_3906	1.72e-21	94.0	COG0008@1|root,COG0008@2|Bacteria,4NP0Y@976|Bacteroidetes,47Q0Q@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CSH2_k127_1293652_0	1134474.O59_003361	4.109e-133	432.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1FGGP@10|Cellvibrio	1236|Gammaproteobacteria	G	Glyco_18	chiA1	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,Glyco_hydro_18,fn3
CSH2_k127_1293718_0	700598.Niako_3539	7.995e-89	297.0	COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1IVXC@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CSH2_k127_1293718_2	925409.KI911562_gene1308	1.232e-54	194.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,1ISAQ@117747|Sphingobacteriia	976|Bacteroidetes	S	MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
CSH2_k127_1293718_1	925409.KI911562_gene1307	3.773e-64	222.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CSH2_k127_1294484_0	700598.Niako_0971	2.433e-195	612.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1IQP6@117747|Sphingobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CSH2_k127_1296724_0	1270196.JCKI01000002_gene135	1.594e-193	619.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1IRKN@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CSH2_k127_1299275_0	925409.KI911562_gene2963	2.005e-164	527.0	COG2308@1|root,COG2308@2|Bacteria,4NG4D@976|Bacteroidetes,1IRDC@117747|Sphingobacteriia	976|Bacteroidetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1299275_2	925409.KI911562_gene1838	7.639e-68	237.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,1IP2M@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CSH2_k127_1299275_1	925409.KI911562_gene1839	6.382e-90	299.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1IS2H@117747|Sphingobacteriia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
CSH2_k127_130679_2	700598.Niako_5525	3.439e-127	415.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1IPWE@117747|Sphingobacteriia	976|Bacteroidetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
CSH2_k127_130679_3	1268240.ATFI01000013_gene1178	1.062e-07	55.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_130679_0	1267211.KI669560_gene505	6.818e-251	782.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CSH2_k127_130679_1	1123057.P872_04760	2.518e-162	536.0	COG3291@1|root,COG5498@1|root,COG3291@2|Bacteria,COG5498@2|Bacteria,4PPR2@976|Bacteroidetes,47YQN@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1310973_0	925409.KI911562_gene302	1.215e-163	517.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_1312122_1	1267211.KI669560_gene2761	1.619e-33	133.0	2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,1ITUK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1312122_0	1239962.C943_02333	3.86e-74	252.0	COG1274@1|root,COG1274@2|Bacteria,4NIPX@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CSH2_k127_1318659_0	925409.KI911562_gene1481	2.091e-129	421.0	COG1208@1|root,COG1208@2|Bacteria,4NIRW@976|Bacteroidetes,1IVAZ@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CSH2_k127_1318659_1	1267211.KI669560_gene1034	6.933e-29	116.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1ITA3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CSH2_k127_1319818_1	700598.Niako_6054	1.935e-104	346.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1IPSX@117747|Sphingobacteriia	976|Bacteroidetes	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
CSH2_k127_1319818_0	925409.KI911562_gene386	4.53e-202	640.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1IQIK@117747|Sphingobacteriia	976|Bacteroidetes	K	RNA polymerase, sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CSH2_k127_1319818_3	700598.Niako_6237	1.375e-39	155.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,1IUI6@117747|Sphingobacteriia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1319818_2	1123248.KB893331_gene3807	7.851e-59	213.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,1IT01@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
CSH2_k127_1320593_0	945713.IALB_2618	3.995e-118	384.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CSH2_k127_1320593_1	760192.Halhy_3124	2.41e-62	225.0	COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,1IP2K@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
CSH2_k127_1324109_0	1267211.KI669560_gene1203	3.761e-273	846.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CSH2_k127_1326171_0	700598.Niako_0329	5.07e-154	490.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1IR18@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CSH2_k127_1326171_1	378806.STAUR_0746	2.66e-14	73.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,435G1@68525|delta/epsilon subdivisions,2WZTI@28221|Deltaproteobacteria,2Z2QB@29|Myxococcales	28221|Deltaproteobacteria	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
CSH2_k127_1333755_1	234267.Acid_1421	0.0005321	52.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CSH2_k127_1333755_0	700598.Niako_2108	1.303e-59	213.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CSH2_k127_1334328_0	700598.Niako_1623	4.495e-224	708.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IP25@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CSH2_k127_1334328_1	1123248.KB893321_gene539	2.459e-41	161.0	COG4399@1|root,COG4399@2|Bacteria,4NIDM@976|Bacteroidetes,1IZQF@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
CSH2_k127_1334328_2	700598.Niako_1621	5.854e-24	107.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
CSH2_k127_1344077_0	649349.Lbys_3011	6.997e-119	394.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y6D@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CSH2_k127_1353278_2	1202532.FF52_05570	5.824e-17	83.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IDFJ@117743|Flavobacteriia,2NY9D@237|Flavobacterium	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CSH2_k127_1353278_0	700598.Niako_5234	3.283e-141	462.0	COG4299@1|root,COG4299@2|Bacteria,4NJZJ@976|Bacteroidetes,1IR3E@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
CSH2_k127_1353278_1	714943.Mucpa_2717	2.67e-44	173.0	COG4632@1|root,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes,1ITPU@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,fn3
CSH2_k127_1354045_0	2423.NA23_0204270	2.456e-109	371.0	COG0367@1|root,COG0367@2|Bacteria,2GDF1@200918|Thermotogae	200918|Thermotogae	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CSH2_k127_1354139_0	1189612.A33Q_0629	4.401e-129	421.0	COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
CSH2_k127_1354139_1	1189612.A33Q_0628	1.435e-05	50.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipoxygenase
CSH2_k127_13595_0	1202532.FF52_10383	1.224e-19	103.0	2DBFN@1|root,2Z8ZF@2|Bacteria,4NGEI@976|Bacteroidetes,1I0I2@117743|Flavobacteriia,2NUGP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_13595_1	313606.M23134_02493	2.056e-17	87.0	28JKB@1|root,2Z9D6@2|Bacteria,4NJC1@976|Bacteroidetes,47PI3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1361180_1	1185876.BN8_04793	1.982e-49	181.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CSH2_k127_1361180_0	485918.Cpin_0242	1.972e-81	274.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1IQC9@117747|Sphingobacteriia	976|Bacteroidetes	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CSH2_k127_1381163_2	700598.Niako_5037	1.129e-36	143.0	COG4748@1|root,COG4748@2|Bacteria,4PN76@976|Bacteroidetes,1J0M4@117747|Sphingobacteriia	976|Bacteroidetes	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
CSH2_k127_1381163_0	1267211.KI669560_gene2367	4.566e-150	477.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CSH2_k127_1381163_1	1267211.KI669560_gene2373	1.575e-81	273.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1INNG@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CSH2_k127_1382725_1	1239962.C943_04399	2.375e-06	54.0	2EVC1@1|root,33NSI@2|Bacteria,4NZJK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1382725_0	388413.ALPR1_17383	6.48e-47	173.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47PG1@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K01802,ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CSH2_k127_1384007_0	929713.NIASO_05365	2.258e-95	322.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1IV9F@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CSH2_k127_1397822_2	1166018.FAES_4777	1.548e-29	121.0	COG1225@1|root,COG1225@2|Bacteria,4NNHI@976|Bacteroidetes,47PTD@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CSH2_k127_1397822_1	925409.KI911562_gene1498	2.073e-59	212.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1IQBR@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CSH2_k127_1397822_0	1123248.KB893322_gene595	0.0	2206.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1INS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CSH2_k127_1401134_2	1123248.KB893325_gene1168	7.266e-33	132.0	COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes,1J0CK@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CSH2_k127_1401134_1	1279009.ADICEAN_03751	8.586e-43	165.0	2CEQ4@1|root,2ZUK4@2|Bacteria,4NPFT@976|Bacteroidetes,47Q4S@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1401134_0	925409.KI911562_gene437	5.794e-75	268.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1IPE9@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
CSH2_k127_1406782_0	1267211.KI669560_gene1677	2.094e-131	421.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CSH2_k127_1406782_1	929556.Solca_2062	1.767e-25	122.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1IPNA@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	aefA	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
CSH2_k127_1408587_1	925409.KI911562_gene1783	6.974e-56	206.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,1ISAD@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein (DUF2154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
CSH2_k127_1408587_0	1002809.SSIL_0829	1.044e-82	282.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,26DX5@186818|Planococcaceae	91061|Bacilli	P	Mn2 and Fe2 transporters of the NRAMP family	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
CSH2_k127_141207_0	925409.KI911562_gene1681	3.303e-158	508.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1IQVW@117747|Sphingobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_141207_1	991.IW20_23975	5.497e-28	119.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,1IJ8C@117743|Flavobacteriia	976|Bacteroidetes	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
CSH2_k127_1412859_0	1267211.KI669560_gene2700	2.737e-203	636.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes	976|Bacteroidetes	E	Choline dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CSH2_k127_1415599_1	925409.KI911562_gene1304	3.977e-70	241.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1IW4H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CSH2_k127_1415599_0	1267211.KI669560_gene2746	3.941e-152	496.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1IPM6@117747|Sphingobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CSH2_k127_1415599_3	224911.27355642	0.0001105	50.0	COG3832@1|root,COG3832@2|Bacteria,1RB46@1224|Proteobacteria,2U5JZ@28211|Alphaproteobacteria,3JY84@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CSH2_k127_1415599_2	700598.Niako_0462	8.902e-52	190.0	2C0BR@1|root,32Z3H@2|Bacteria,4NVDW@976|Bacteroidetes,1IU2Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
CSH2_k127_1419312_1	929556.Solca_2696	3.311e-68	239.0	COG2755@1|root,COG2755@2|Bacteria,4NPB3@976|Bacteroidetes,1J195@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CSH2_k127_1419312_0	762903.Pedsa_0022	4.505e-69	237.0	COG0477@1|root,COG2814@2|Bacteria,4NG5F@976|Bacteroidetes	976|Bacteroidetes	EGP	Psort location CytoplasmicMembrane, score 10.00	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CSH2_k127_1429086_0	700598.Niako_6564	3.512e-132	431.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IRWK@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CSH2_k127_1429086_1	1123277.KB893172_gene658	2.893e-67	237.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
CSH2_k127_1431884_0	929703.KE386491_gene712	7.249e-311	974.0	COG4206@1|root,COG4206@2|Bacteria,4NH06@976|Bacteroidetes,47MID@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_1440727_0	700598.Niako_6431	3.336e-129	414.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,1IPNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CSH2_k127_1440727_1	1189620.AJXL01000113_gene3267	6.561e-18	85.0	COG0708@1|root,COG0708@2|Bacteria,4NF57@976|Bacteroidetes,1I0AN@117743|Flavobacteriia,2NT27@237|Flavobacterium	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_144303_1	1267211.KI669560_gene2394	1.097e-207	656.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1INS9@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CSH2_k127_144303_2	700598.Niako_5069	2.469e-151	492.0	COG1858@1|root,COG1858@2|Bacteria,4NM2S@976|Bacteroidetes,1IVVD@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CSH2_k127_144303_0	1123248.KB893370_gene5091	8.629e-215	677.0	COG1793@1|root,COG1793@2|Bacteria,4NEKP@976|Bacteroidetes,1IQCK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
CSH2_k127_1448844_0	1123248.KB893348_gene360	2.806e-68	237.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1IR38@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1449257_0	43989.cce_0241	8.736e-53	197.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria,3KGI1@43988|Cyanothece	1117|Cyanobacteria	H	UbiA prenyltransferase	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
CSH2_k127_1449257_1	1227739.Hsw_3254	2.849e-18	93.0	298PG@1|root,2ZVTY@2|Bacteria,4NP4F@976|Bacteroidetes,47PR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1449596_0	1296416.JACB01000029_gene4193	1.647e-108	366.0	COG5412@1|root,COG5412@2|Bacteria,4NJXH@976|Bacteroidetes,1HYSA@117743|Flavobacteriia,2YHCW@290174|Aquimarina	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Endonuclea_NS_2
CSH2_k127_1454009_2	1123248.KB893337_gene2456	5.978e-106	347.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,1IQK5@117747|Sphingobacteriia	976|Bacteroidetes	H	Sigma-54 interaction domain	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
CSH2_k127_1454009_1	468059.AUHA01000002_gene562	4.876e-107	356.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,1IQHC@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG3781 membrane protein	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
CSH2_k127_1454009_0	700598.Niako_3673	3.458e-140	453.0	COG0673@1|root,COG0673@2|Bacteria,4NEQB@976|Bacteroidetes,1IPA3@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	yvaA	-	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CSH2_k127_1454009_3	1267211.KI669560_gene2099	1.009e-63	224.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
CSH2_k127_1461372_2	880071.Fleli_1683	3.499e-12	75.0	2EMGK@1|root,32VI4@2|Bacteria,4NSE2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1461372_0	1313301.AUGC01000003_gene2121	2.307e-48	188.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CSH2_k127_1461372_1	1239962.C943_04601	7.523e-39	156.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,47PBG@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CSH2_k127_1466390_0	700598.Niako_5047	6.361e-101	329.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CSH2_k127_1469683_0	700598.Niako_7214	1.598e-101	332.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
CSH2_k127_1469683_1	700598.Niako_7213	8.394e-50	182.0	COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,1ISCW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CSH2_k127_1469683_2	700598.Niako_7212	8.906e-30	118.0	COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,1IQCF@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CSH2_k127_1472561_1	1267211.KI669560_gene2544	4.465e-22	97.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1INWV@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
CSH2_k127_1472561_0	1033810.HLPCO_000774	9.301e-78	268.0	COG0524@1|root,COG0524@2|Bacteria,2NRNB@2323|unclassified Bacteria	2|Bacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.15,2.7.1.187,2.7.1.45	ko:K00852,ko:K00874,ko:K19978	ko00030,ko00525,ko01100,ko01120,ko01130,ko01200,map00030,map00525,map01100,map01120,map01130,map01200	M00061,M00308,M00631	R01051,R01541,R02750,R11184	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CSH2_k127_1473591_0	1267211.KI669560_gene518	6.169e-188	595.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CSH2_k127_1483430_0	700598.Niako_6312	9.096e-89	298.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1IRZ0@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CSH2_k127_1483430_2	925409.KI911562_gene818	2.548e-44	168.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,1ITSR@117747|Sphingobacteriia	976|Bacteroidetes	E	Lysine exporter protein (Lyse ygga)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CSH2_k127_1483430_1	925409.KI911562_gene820	2.529e-51	184.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,1IVSR@117747|Sphingobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CSH2_k127_1493106_0	1267211.KI669560_gene861	1.247e-114	375.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1IPMR@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CSH2_k127_1493106_1	700598.Niako_6857	5.532e-96	324.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1IQ08@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility associated	gldN	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1493106_2	700598.Niako_6856	7.12e-85	291.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
CSH2_k127_1497633_0	1123248.KB893314_gene3570	1.226e-50	184.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1IRTC@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CSH2_k127_1497633_1	700598.Niako_0176	1.895e-50	181.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
CSH2_k127_1497633_2	694427.Palpr_2067	7.238e-07	51.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,2FP15@200643|Bacteroidia,22X8S@171551|Porphyromonadaceae	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CSH2_k127_1500895_0	649349.Lbys_0966	4.798e-71	244.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CSH2_k127_1500895_1	153721.MYP_4368	1.256e-54	193.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CSH2_k127_1506106_1	1267211.KI669560_gene2126	7.506e-45	168.0	COG0484@1|root,COG0484@2|Bacteria,4NSI9@976|Bacteroidetes,1ITFJ@117747|Sphingobacteriia	976|Bacteroidetes	O	HSCB C-terminal oligomerisation domain	-	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
CSH2_k127_1506106_3	485918.Cpin_3523	1.035e-05	55.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CSH2_k127_1506106_2	7955.ENSDARP00000108987	1.611e-08	64.0	KOG3538@1|root,KOG4597@2759|Eukaryota,39NNX@33154|Opisthokonta,3CQ7D@33208|Metazoa,3E6CD@33213|Bilateria,48RTP@7711|Chordata,49N77@7742|Vertebrata	33208|Metazoa	O	BPTI/Kunitz family of serine protease inhibitors.	-	-	-	-	-	-	-	-	-	-	-	-	Kunitz_BPTI
CSH2_k127_1506106_0	1122605.KB893625_gene1819	1.115e-77	265.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1INWM@117747|Sphingobacteriia	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CSH2_k127_1513656_0	1122605.KB893630_gene4045	2.996e-191	602.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1IPT9@117747|Sphingobacteriia	976|Bacteroidetes	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CSH2_k127_1513656_1	743722.Sph21_2289	7.447e-49	177.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1IPTP@117747|Sphingobacteriia	976|Bacteroidetes	EH	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CSH2_k127_1517193_1	1185876.BN8_05853	1.874e-12	74.0	COG2143@1|root,COG2143@2|Bacteria,4PJZE@976|Bacteroidetes,47Q3S@768503|Cytophagia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1517193_0	641524.ADICYQ_1388	2.151e-41	158.0	2BW9M@1|root,32RJH@2|Bacteria,4NTHJ@976|Bacteroidetes,47RBU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_153278_0	1185876.BN8_00055	5.988e-75	268.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_1538338_1	1267211.KI669560_gene2548	1.581e-26	111.0	COG2859@1|root,COG2859@2|Bacteria,4NI76@976|Bacteroidetes,1IS8C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
CSH2_k127_1538338_0	1239962.C943_00072	3.703e-72	245.0	COG2318@1|root,COG2318@2|Bacteria,4NGXE@976|Bacteroidetes,47RA5@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
CSH2_k127_1539499_0	1267211.KI669560_gene1788	3.313e-84	289.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1IPIG@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CSH2_k127_1539499_1	1123248.KB893326_gene1329	2.801e-78	270.0	COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes,1IPTM@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
CSH2_k127_1554502_1	1123057.P872_07695	5.126e-38	150.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1554502_0	925409.KI911562_gene2360	4.02e-88	292.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1IQ2K@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CSH2_k127_1558564_0	1121875.KB907548_gene1528	9.157e-108	364.0	COG2355@1|root,COG2355@2|Bacteria,4NI3V@976|Bacteroidetes,1I0XS@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
CSH2_k127_15589_0	1279009.ADICEAN_02824	5.892e-82	284.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_1563266_0	1267211.KI669560_gene1902	1.397e-156	495.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,1INSE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CSH2_k127_1563266_1	714943.Mucpa_4224	4.37e-55	202.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CSH2_k127_1565156_2	925409.KI911562_gene1525	8.196e-95	316.0	COG1232@1|root,COG1232@2|Bacteria,4NJNP@976|Bacteroidetes	976|Bacteroidetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CSH2_k127_1565156_1	700598.Niako_4446	1.318e-150	490.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,1IP76@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CSH2_k127_1565156_4	1267211.KI669560_gene1642	2.46e-37	145.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1565156_3	445961.IW15_21345	2.022e-63	222.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1I1ES@117743|Flavobacteriia,3ZQZJ@59732|Chryseobacterium	976|Bacteroidetes	O	HupE UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CSH2_k127_1565156_0	925409.KI911562_gene2863	1.854e-297	919.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IWX4@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_1567372_2	1267211.KI669560_gene1037	1.286e-64	223.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1ISVM@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CSH2_k127_1567372_1	1123248.KB893385_gene4788	1.962e-95	317.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CSH2_k127_1567372_0	925409.KI911562_gene1410	2.289e-221	691.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CSH2_k127_1572611_0	1123248.KB893326_gene1293	1.165e-95	319.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_1572611_1	1034807.FBFL15_1323	6.342e-73	254.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZB@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
CSH2_k127_1576213_2	114615.BRADO2482	3.596e-20	94.0	COG0348@1|root,COG0348@2|Bacteria,1R8G0@1224|Proteobacteria,2U46K@28211|Alphaproteobacteria,3JX79@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1576213_0	1123248.KB893386_gene1827	9.703e-47	172.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1ITN4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
CSH2_k127_1576213_1	1267211.KI669560_gene117	1.348e-41	158.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ITMD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CSH2_k127_1576630_0	1267211.KI669560_gene2369	2.503e-257	803.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CSH2_k127_1576630_3	926562.Oweho_0194	1.219e-10	64.0	2BZQ6@1|root,339SI@2|Bacteria,4NXJG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1576630_2	1123248.KB893386_gene1870	1.896e-89	299.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,1INSK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CSH2_k127_1576630_1	1267211.KI669560_gene2251	2.398e-116	379.0	COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1IPYJ@117747|Sphingobacteriia	976|Bacteroidetes	F	GMP synthase-glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
CSH2_k127_1581939_0	388413.ALPR1_02135	1.032e-210	663.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CSH2_k127_1586989_1	1267211.KI669560_gene691	1.613e-13	77.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CSH2_k127_1586989_0	929713.NIASO_12445	7.801e-46	175.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_1588053_0	700598.Niako_5592	6.888e-154	493.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CSH2_k127_1592200_1	1122605.KB893649_gene3826	6.681e-64	220.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
CSH2_k127_1592200_0	925409.KI911562_gene548	3.959e-132	428.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1IP1D@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CSH2_k127_1592200_2	925409.KI911562_gene547	3.221e-32	128.0	COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CSH2_k127_1592483_0	1408473.JHXO01000007_gene879	5.476e-96	326.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,2FN29@200643|Bacteroidia	976|Bacteroidetes	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CSH2_k127_1592483_1	449447.MAE_42820	2.717e-32	131.0	COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,1G4I8@1117|Cyanobacteria	1117|Cyanobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
CSH2_k127_1600767_2	485918.Cpin_3069	1.514e-46	174.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1IS81@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CSH2_k127_1600767_4	1267211.KI669560_gene2624	5.988e-24	102.0	2E3ZY@1|root,32YWV@2|Bacteria,4P40E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1600767_1	929713.NIASO_07760	1.845e-50	182.0	COG0607@1|root,COG0607@2|Bacteria,4P495@976|Bacteroidetes,1IYNV@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CSH2_k127_1600767_0	925409.KI911562_gene2102	1.388e-154	500.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CSH2_k127_1600767_3	1121481.AUAS01000036_gene5167	1.802e-25	108.0	COG2026@1|root,COG2026@2|Bacteria,4NVIF@976|Bacteroidetes,47SMY@768503|Cytophagia	976|Bacteroidetes	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CSH2_k127_1600767_5	1120968.AUBX01000015_gene3746	1.101e-10	64.0	2BWKX@1|root,33G81@2|Bacteria,4NYKR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
CSH2_k127_1605398_0	172088.AUGA01000016_gene2484	3.308e-106	367.0	COG1409@1|root,COG1409@2|Bacteria,1RHP4@1224|Proteobacteria,2U9B6@28211|Alphaproteobacteria,3K0V6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CSH2_k127_1611614_0	925409.KI911562_gene2325	1.523e-189	607.0	COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1IW0D@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_1611857_0	1122621.ATZA01000001_gene1990	1.412e-257	811.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQA8@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CSH2_k127_1615767_0	1122605.KB893626_gene2525	9.137e-38	144.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1INPX@117747|Sphingobacteriia	976|Bacteroidetes	C	oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CSH2_k127_1615767_1	1122605.KB893626_gene2526	6.653e-36	141.0	COG5605@1|root,COG5605@2|Bacteria,4PGS2@976|Bacteroidetes,1IU6V@117747|Sphingobacteriia	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
CSH2_k127_1615767_2	700598.Niako_6480	6.704e-26	110.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CSH2_k127_1622687_0	700598.Niako_4516	2.739e-141	462.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1IP8V@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CSH2_k127_1622687_1	1158294.JOMI01000003_gene2044	7.884e-23	102.0	COG2518@1|root,COG2518@2|Bacteria,4NR16@976|Bacteroidetes,2FXYB@200643|Bacteroidia	976|Bacteroidetes	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CSH2_k127_1623931_1	714943.Mucpa_5243	8.728e-54	192.0	COG0680@1|root,COG0680@2|Bacteria,4NRQY@976|Bacteroidetes,1IT7D@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0680 Ni Fe-hydrogenase maturation factor	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
CSH2_k127_1623931_0	925409.KI911562_gene1454	1.499e-148	484.0	COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_1623931_2	886293.Sinac_0326	3.401e-46	178.0	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CSH2_k127_1627480_2	1123008.KB905696_gene3044	3.505e-13	70.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,2FME1@200643|Bacteroidia,22XFR@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
CSH2_k127_1627480_0	700598.Niako_6051	8.186e-146	467.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
CSH2_k127_1627480_1	1454007.JAUG01000059_gene3537	1.326e-14	83.0	COG0457@1|root,COG0457@2|Bacteria	1454007.JAUG01000059_gene3537|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1633462_1	1123248.KB893348_gene212	6.553e-47	177.0	COG3637@1|root,COG3637@2|Bacteria,4NNPF@976|Bacteroidetes,1ISTC@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CSH2_k127_1633462_0	1267211.KI669560_gene284	3.861e-116	376.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CSH2_k127_1636677_0	700598.Niako_7214	2.265e-187	588.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
CSH2_k127_1636677_1	700598.Niako_7215	1.493e-28	117.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1INP9@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CSH2_k127_1644886_1	1122605.KB893647_gene486	8.32e-28	124.0	2DQH4@1|root,336TE@2|Bacteria,4NXA3@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CSH2_k127_1644886_0	1123248.KB893326_gene1494	1.79e-185	583.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CSH2_k127_1644886_2	504472.Slin_2766	3.98e-11	72.0	28NAV@1|root,2ZBEH@2|Bacteria,4NJGP@976|Bacteroidetes,47T10@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1654713_0	1279009.ADICEAN_01609	1.929e-61	224.0	COG4249@1|root,COG4249@2|Bacteria,4NH9I@976|Bacteroidetes,47V1R@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
CSH2_k127_1666143_1	700598.Niako_0443	8.491e-82	274.0	COG2836@1|root,COG2836@2|Bacteria,4NIC3@976|Bacteroidetes,1IUX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CSH2_k127_1666143_0	688270.Celal_4232	1.058e-101	344.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes,1I2DH@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CSH2_k127_1667971_1	925409.KI911562_gene510	3.228e-41	154.0	COG2908@1|root,COG2908@2|Bacteria,4NFD8@976|Bacteroidetes,1IQAN@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
CSH2_k127_1667971_0	938709.AUSH02000033_gene1428	9.038e-115	379.0	COG1819@1|root,COG1819@2|Bacteria,4NFYF@976|Bacteroidetes	976|Bacteroidetes	CG	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
CSH2_k127_1671160_2	1122176.KB903536_gene1872	8.987e-14	74.0	COG3876@1|root,COG3876@2|Bacteria,4NKHR@976|Bacteroidetes,1IWXE@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CSH2_k127_1671160_1	1267211.KI669560_gene58	3.368e-56	203.0	COG1853@1|root,COG1853@2|Bacteria,4NG6I@976|Bacteroidetes,1IT4J@117747|Sphingobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CSH2_k127_1671160_0	700598.Niako_6719	6.527e-96	322.0	COG3023@1|root,COG3023@2|Bacteria,4NE38@976|Bacteroidetes,1INQE@117747|Sphingobacteriia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	amiD	-	3.5.1.28	ko:K01447,ko:K11066	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1
CSH2_k127_1680187_0	925409.KI911562_gene2238	1.107e-149	478.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CSH2_k127_1680187_1	925409.KI911562_gene2239	1.673e-147	469.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CSH2_k127_1681002_0	700598.Niako_0134	8.169e-109	364.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,1IXHP@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
CSH2_k127_1690017_1	1166018.FAES_5035	1.168e-54	200.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47KT8@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CSH2_k127_1690017_0	1267211.KI669560_gene472	5.211e-137	445.0	COG0644@1|root,COG0644@2|Bacteria,4PMBP@976|Bacteroidetes,1IQ1V@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CSH2_k127_1691547_2	1122605.KB893625_gene1792	2.578e-27	115.0	COG1280@1|root,COG1280@2|Bacteria,4NUV7@976|Bacteroidetes,1IUGQ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CSH2_k127_1691547_0	925409.KI911562_gene2892	1.076e-140	451.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1IP0Z@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CSH2_k127_1691547_1	700598.Niako_1599	6.594e-67	230.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CSH2_k127_170549_0	1267211.KI669560_gene1892	2.104e-174	560.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_170549_1	925409.KI911562_gene2487	1.832e-68	237.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1IS1B@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CSH2_k127_1707211_1	1267211.KI669560_gene655	1.646e-44	166.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1IT21@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CSH2_k127_1707211_0	1123248.KB893322_gene570	1.132e-127	415.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1IQB4@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
CSH2_k127_1711781_0	1296416.JACB01000029_gene4193	4.235e-123	407.0	COG5412@1|root,COG5412@2|Bacteria,4NJXH@976|Bacteroidetes,1HYSA@117743|Flavobacteriia,2YHCW@290174|Aquimarina	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Endonuclea_NS_2
CSH2_k127_1711938_0	1122605.KB893626_gene2686	1.391e-40	156.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CSH2_k127_1711938_1	379066.GAU_3313	1.164e-26	124.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1ZV5X@142182|Gemmatimonadetes	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3,Reg_prop,Y_Y_Y
CSH2_k127_1712875_1	87626.PTD2_04611	6.166e-44	163.0	COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,1RQPZ@1236|Gammaproteobacteria,2Q0KK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CSH2_k127_1712875_0	700598.Niako_2188	5.012e-152	485.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_1724500_1	471854.Dfer_5262	3.431e-28	123.0	COG2133@1|root,COG5295@1|root,COG2133@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	3.2.1.4	ko:K01179,ko:K19233,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40,1.B.40.2	GH5,GH9	-	Collagen,ESPR,Haemagg_act,YadA_anchor,YadA_head,YadA_stalk
CSH2_k127_1724500_0	1267211.KI669560_gene2870	7.575e-98	326.0	COG4760@1|root,COG4760@2|Bacteria,4NNIN@976|Bacteroidetes,1IXW4@117747|Sphingobacteriia	976|Bacteroidetes	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
CSH2_k127_1730182_1	925409.KI911562_gene1161	9.271e-65	223.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_1730182_0	1267211.KI669560_gene861	4.318e-141	454.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1IPMR@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CSH2_k127_1761227_0	1122176.KB903536_gene1848	2.313e-108	359.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IVNE@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	F5_F8_type_C,Glyco_hydro_3,Glyco_hydro_3_C,fn3
CSH2_k127_1761227_1	700598.Niako_5667	4.252e-74	252.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_1765729_0	760192.Halhy_1214	1.369e-114	375.0	COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1IQRX@117747|Sphingobacteriia	976|Bacteroidetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CSH2_k127_1765729_1	471854.Dfer_4283	2.238e-11	65.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NGHV@976|Bacteroidetes,47PQJ@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
CSH2_k127_1773214_0	1267211.KI669560_gene1379	3.681e-68	237.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,1IPXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CSH2_k127_1773214_2	1121373.KB903662_gene179	8.758e-40	151.0	COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,47RM9@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.7.2.1	ko:K00368,ko:K00405	ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020	M00156,M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3
CSH2_k127_1773214_1	641524.ADICYQ_1790	2.621e-48	174.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47JGM@768503|Cytophagia	976|Bacteroidetes	G	COGs COG2133 Glucose sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
CSH2_k127_1777937_1	929562.Emtol_1681	4.834e-37	142.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CSH2_k127_1777937_0	700598.Niako_1014	2.084e-90	302.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1IWRU@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CSH2_k127_17795_0	925409.KI911562_gene1215	9.115e-95	315.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CSH2_k127_17795_1	1122605.KB893626_gene2543	4.808e-36	139.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CSH2_k127_17795_2	929713.NIASO_14175	3.248e-26	109.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CSH2_k127_1780764_0	700598.Niako_6295	1.674e-139	448.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IWYY@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CSH2_k127_1780764_1	700598.Niako_6296	8.821e-52	191.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes,1IUNH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CSH2_k127_1801502_1	866536.Belba_0222	1.811e-14	75.0	COG0637@1|root,COG0637@2|Bacteria,4NHHK@976|Bacteroidetes,47KFT@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CSH2_k127_1801502_0	700598.Niako_5694	1.976e-143	460.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CSH2_k127_1831862_0	700598.Niako_2564	5.97e-109	364.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,1ISMP@117747|Sphingobacteriia	976|Bacteroidetes	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CSH2_k127_1838165_2	700598.Niako_5810	5.537e-17	81.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,1IRUG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CSH2_k127_1838165_0	1123248.KB893321_gene470	2.022e-152	496.0	COG1566@1|root,COG1566@2|Bacteria,4PMCY@976|Bacteroidetes,1J0U2@117747|Sphingobacteriia	976|Bacteroidetes	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CSH2_k127_1838165_1	1122605.KB893637_gene3292	5.213e-92	314.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IP2E@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CSH2_k127_1849165_0	1267211.KI669560_gene1247	5.323e-219	700.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IP84@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_1851189_0	1121889.AUDM01000005_gene1732	0.0	1472.0	28HKI@1|root,2Z7VC@2|Bacteria,4NFS2@976|Bacteroidetes,1HYBU@117743|Flavobacteriia,2NVRT@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_185371_1	288000.BBta_2828	3.108e-73	258.0	COG0348@1|root,COG0348@2|Bacteria,1R8G0@1224|Proteobacteria,2U46K@28211|Alphaproteobacteria,3JX79@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_185371_0	1267211.KI669560_gene114	2.026e-95	315.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CSH2_k127_1856172_1	925409.KI911562_gene612	1.597e-232	728.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_1856172_0	1123248.KB893319_gene4058	5.261e-275	857.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CSH2_k127_1861412_0	700598.Niako_1007	2.435e-108	359.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1ISHE@117747|Sphingobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CSH2_k127_1861412_2	700598.Niako_1006	8.774e-35	138.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes	976|Bacteroidetes	M	InterPro IPR011467	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CSH2_k127_1861412_1	925409.KI911562_gene2320	4.445e-43	160.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1ITXA@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CSH2_k127_1865829_0	1267211.KI669560_gene1029	1.067e-106	352.0	COG0366@1|root,COG0366@2|Bacteria,4NI8U@976|Bacteroidetes,1IUZK@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
CSH2_k127_1865829_1	1267211.KI669560_gene1030	1.217e-41	154.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,1IUE3@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CSH2_k127_1867281_0	471854.Dfer_0532	1.069e-39	164.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,Glug
CSH2_k127_1869697_0	1123248.KB893319_gene4072	6.165e-265	820.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IQ2Z@117747|Sphingobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CSH2_k127_1879515_0	1122621.ATZA01000009_gene323	1.629e-243	760.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPJF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
CSH2_k127_1879515_1	1168289.AJKI01000002_gene2346	3.365e-97	332.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,2FM0Q@200643|Bacteroidia,3XKH3@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
CSH2_k127_1879515_4	1270196.JCKI01000002_gene298	1.326e-49	181.0	2ATIR@1|root,31J2R@2|Bacteria,4NR1Z@976|Bacteroidetes,1ISR5@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
CSH2_k127_1879515_3	1267211.KI669560_gene2073	9.712e-68	234.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1IRYB@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CSH2_k127_1879515_2	929713.NIASO_12330	5.314e-92	303.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1IQ3D@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CSH2_k127_1892902_0	1267211.KI669560_gene410	1.617e-129	418.0	COG0524@1|root,COG0524@2|Bacteria,4PIYB@976|Bacteroidetes,1IYXP@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CSH2_k127_1892902_1	1082931.KKY_1068	1.897e-26	111.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria,3N7QQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
CSH2_k127_1895545_2	485918.Cpin_7081	3.02e-124	404.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1INYT@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1895545_0	1121904.ARBP01000018_gene2707	3.831e-135	445.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,47YNU@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CSH2_k127_1895545_3	1107311.Q767_10125	1.974e-72	251.0	COG3637@1|root,COG3637@2|Bacteria,4NPV9@976|Bacteroidetes,1I47X@117743|Flavobacteriia,2NSX3@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CSH2_k127_1895545_1	485918.Cpin_7084	2.469e-132	428.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CSH2_k127_1904697_1	1123248.KB893315_gene2998	4.96e-72	245.0	COG3391@1|root,COG3391@2|Bacteria,4NER2@976|Bacteroidetes,1IQ4S@117747|Sphingobacteriia	976|Bacteroidetes	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CSH2_k127_1904697_0	1120968.AUBX01000018_gene2161	6.6e-121	400.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,47JI6@768503|Cytophagia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CSH2_k127_1907748_1	1123248.KB893348_gene112	3.246e-11	72.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CSH2_k127_1907748_0	700598.Niako_6727	8.478e-33	138.0	COG1514@1|root,COG1514@2|Bacteria,4NX5U@976|Bacteroidetes,1IYZ5@117747|Sphingobacteriia	976|Bacteroidetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CSH2_k127_1911686_3	1267211.KI669560_gene2395	2.762e-21	96.0	COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,1IS9J@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CSH2_k127_1911686_0	700598.Niako_5097	7.667e-138	443.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,1IQR5@117747|Sphingobacteriia	976|Bacteroidetes	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CSH2_k127_1911686_1	925409.KI911562_gene368	1.474e-78	267.0	COG0122@1|root,COG0122@2|Bacteria,4NMMI@976|Bacteroidetes,1IU7D@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM HhH-GPD superfamily base excision DNA repair protein	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CSH2_k127_1911686_4	1235803.C825_02632	1.686e-06	51.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,2FM5I@200643|Bacteroidia,22XPJ@171551|Porphyromonadaceae	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
CSH2_k127_1911686_2	1089547.KB913013_gene2602	6.646e-23	102.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,47QBX@768503|Cytophagia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
CSH2_k127_1912116_1	929713.NIASO_14075	3.98e-20	90.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1ITY0@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CSH2_k127_1912116_0	700598.Niako_6902	8.163e-133	434.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CSH2_k127_1914830_0	1379270.AUXF01000003_gene3550	2.063e-243	758.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_1917160_0	600809.BPLAN_123	5.885e-159	509.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,3IVEG@39782|Blattabacteriaceae	976|Bacteroidetes	I	Acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CSH2_k127_1917160_1	929556.Solca_3250	1.136e-39	149.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CSH2_k127_1918647_0	485913.Krac_10336	2.96e-89	306.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1_4
CSH2_k127_1936002_0	925409.KI911562_gene183	3.486e-65	229.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1IRUN@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CSH2_k127_1936002_1	761193.Runsl_5388	4.175e-61	216.0	COG3358@1|root,COG3358@2|Bacteria,4NFT3@976|Bacteroidetes,47NJY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CSH2_k127_1938276_1	925409.KI911562_gene565	5.954e-55	193.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1IRVU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CSH2_k127_1938276_0	700598.Niako_6782	9.189e-92	307.0	COG1216@1|root,COG1216@2|Bacteria,4NGHQ@976|Bacteroidetes,1IS78@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
CSH2_k127_1949943_0	700598.Niako_4690	9.47e-208	648.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_1955893_1	925409.KI911562_gene1427	2.018e-49	180.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
CSH2_k127_1955893_0	1267211.KI669560_gene1042	1.13e-152	488.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1IQW6@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CSH2_k127_1955893_2	1484460.JSWG01000006_gene2765	2.251e-12	68.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia	976|Bacteroidetes	N	Gliding motility protein GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CSH2_k127_195847_0	700598.Niako_6200	9.185e-99	325.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1IVF8@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
CSH2_k127_195847_1	765952.PUV_26370	7.587e-31	125.0	2E3V1@1|root,32YSA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_196403_0	485918.Cpin_4038	2.253e-83	285.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,1ISCN@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CSH2_k127_196403_1	1123248.KB893320_gene3932	1.648e-37	144.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CSH2_k127_1964107_0	925409.KI911562_gene1468	9.822e-89	302.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IPHC@117747|Sphingobacteriia	976|Bacteroidetes	V	peptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
CSH2_k127_1970724_2	1123248.KB893331_gene3809	1.041e-05	48.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1IS3Y@117747|Sphingobacteriia	976|Bacteroidetes	S	HAD-superfamily hydrolase subfamily IA, variant 3	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
CSH2_k127_1970724_0	1122605.KB893626_gene2451	1.156e-83	285.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes,1IR5D@117747|Sphingobacteriia	976|Bacteroidetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Peptidase_S9
CSH2_k127_1970724_1	491205.JARQ01000001_gene781	1.278e-47	173.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,3ZQ0I@59732|Chryseobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_197136_1	700598.Niako_1001	2.821e-64	224.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1INY0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_197136_0	1267211.KI669560_gene1470	3.446e-182	574.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1IP0Q@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CSH2_k127_1973302_1	1123248.KB893331_gene3779	2.803e-77	269.0	COG3757@1|root,COG3757@2|Bacteria,4NKHF@976|Bacteroidetes,1ISMY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl hydrolases family 25	acm	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
CSH2_k127_1973302_2	269798.CHU_2455	1.335e-13	80.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CSH2_k127_1973302_0	1267211.KI669560_gene114	1.202e-110	360.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CSH2_k127_1977834_0	1267211.KI669560_gene1269	3.689e-43	171.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
CSH2_k127_197823_0	925409.KI911562_gene897	2.533e-103	352.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,1IWQ4@117747|Sphingobacteriia	976|Bacteroidetes	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CSH2_k127_197823_2	700598.Niako_6589	7.772e-49	182.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1IRUD@117747|Sphingobacteriia	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CSH2_k127_197823_1	700598.Niako_6588	4.282e-57	199.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1INU7@117747|Sphingobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CSH2_k127_1984810_1	266762.HQ36_04355	3.663e-12	67.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,2FT42@200643|Bacteroidia,22Y3Q@171551|Porphyromonadaceae	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
CSH2_k127_1984810_0	700598.Niako_4590	2.872e-91	307.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IXCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CSH2_k127_198675_0	925409.KI911562_gene454	2.978e-105	342.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CSH2_k127_198675_1	700598.Niako_6243	5.238e-37	145.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1IT21@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CSH2_k127_198675_2	1123248.KB893331_gene3783	1.255e-09	63.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CSH2_k127_198720_0	700598.Niako_6249	7.889e-122	400.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1IQR6@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CSH2_k127_1988524_3	313590.MED134_12216	1.038e-18	93.0	COG0454@1|root,COG1670@1|root,COG0456@2|Bacteria,COG1670@2|Bacteria,4NSM6@976|Bacteroidetes,1I41U@117743|Flavobacteriia,37E6K@326319|Dokdonia	976|Bacteroidetes	JK	Acetyltransferase (GNAT) domain	yitI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_3
CSH2_k127_1988524_1	925409.KI911562_gene494	7.734e-74	250.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1IS85@117747|Sphingobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
CSH2_k127_1988524_0	1123248.KB893322_gene626	6.075e-111	365.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CSH2_k127_1988524_2	743722.Sph21_4849	1.817e-40	151.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1IQD8@117747|Sphingobacteriia	976|Bacteroidetes	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CSH2_k127_1995251_2	509635.N824_15990	7.257e-18	83.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,1IP7C@117747|Sphingobacteriia	976|Bacteroidetes	E	synthase small subunit	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
CSH2_k127_1995251_0	700598.Niako_0106	2.304e-214	668.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1IQ69@117747|Sphingobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CSH2_k127_1995251_1	700598.Niako_0107	1.676e-91	305.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1INNU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CSH2_k127_2002814_1	1121481.AUAS01000008_gene3124	5.942e-104	339.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,47M1C@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
CSH2_k127_2002814_0	485917.Phep_3637	1.75e-150	490.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IQRK@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
CSH2_k127_2010506_1	1123248.KB893317_gene4321	3.04e-78	265.0	COG1595@1|root,COG1595@2|Bacteria,4NM40@976|Bacteroidetes,1IRKZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CSH2_k127_2010506_0	1123248.KB893317_gene4320	2.074e-102	344.0	COG0265@1|root,COG0265@2|Bacteria,4NGA4@976|Bacteroidetes,1IPPQ@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CSH2_k127_2010720_1	880073.Calab_3356	1.57e-30	124.0	COG0737@1|root,COG1506@1|root,COG2356@1|root,COG4935@1|root,COG0737@2|Bacteria,COG1506@2|Bacteria,COG2356@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.17.18	ko:K05996,ko:K06889,ko:K07214	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CotH,Peptidase_S9,SBP_bac_8,SLH
CSH2_k127_2010720_0	929556.Solca_2566	7.452e-86	289.0	COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,1IPPA@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
CSH2_k127_2015372_1	925409.KI911562_gene2307	5.235e-20	92.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1IT0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2015372_0	700598.Niako_0991	2.437e-186	585.0	COG1884@1|root,COG1884@2|Bacteria,4PN0H@976|Bacteroidetes,1IPCT@117747|Sphingobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CSH2_k127_2025147_0	1267211.KI669560_gene2082	6.805e-173	549.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
CSH2_k127_2025147_1	1123248.KB893314_gene3699	0.0001682	46.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2026808_0	929556.Solca_1050	3.878e-154	498.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1IRDG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_2032092_1	1122176.KB903539_gene1427	5.338e-38	145.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,1IP8Z@117747|Sphingobacteriia	976|Bacteroidetes	S	double-strand break repair	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2032092_0	1296416.JACB01000029_gene4197	2.44e-140	458.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1HYP7@117743|Flavobacteriia,2YIDG@290174|Aquimarina	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CSH2_k127_2034083_0	485918.Cpin_5494	3.961e-232	722.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1IPXI@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CSH2_k127_2034083_2	925409.KI911562_gene1819	5.691e-71	243.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1ITJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CSH2_k127_2034083_1	700598.Niako_0937	5.72e-195	623.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1INQX@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CSH2_k127_2048593_1	1123248.KB893348_gene286	2.214e-58	214.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2048593_0	700598.Niako_6548	7.627e-91	304.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1ISYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CSH2_k127_2048593_2	1122605.KB893646_gene29	8.753e-28	119.0	2DBWT@1|root,2ZBJ6@2|Bacteria,4NRX3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2067538_0	984262.SGRA_3821	6.578e-79	267.0	COG0281@1|root,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,PTA_PTB,malic
CSH2_k127_2067538_1	1341155.FSS13T_23940	7.155e-36	147.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
CSH2_k127_2072433_2	1033743.CAES01000093_gene2744	3.851e-44	162.0	COG3832@1|root,COG3832@2|Bacteria,1V799@1239|Firmicutes,4HHAD@91061|Bacilli,26WTI@186822|Paenibacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CSH2_k127_2072433_1	700598.Niako_6495	8.902e-52	190.0	COG1846@1|root,COG1846@2|Bacteria,4NSNN@976|Bacteroidetes,1ITUW@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CSH2_k127_2072433_0	925409.KI911562_gene1045	1.506e-81	275.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_2080946_0	1123248.KB893314_gene3285	7.123e-78	265.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IQAC@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CSH2_k127_2080946_1	468059.AUHA01000003_gene1730	6.561e-62	217.0	COG3685@1|root,COG3685@2|Bacteria,4P08F@976|Bacteroidetes,1IV02@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
CSH2_k127_2084550_1	485918.Cpin_3663	3.139e-21	93.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1ISGQ@117747|Sphingobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CSH2_k127_2084550_0	1267211.KI669560_gene747	1.601e-79	273.0	2DBS0@1|root,2ZANT@2|Bacteria,4NQP3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2094650_0	929713.NIASO_17110	6.715e-62	223.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
CSH2_k127_2094650_1	925409.KI911562_gene732	7.259e-20	89.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1IQZ5@117747|Sphingobacteriia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CSH2_k127_2094820_0	1235813.JCM10003_2930	3.224e-240	755.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,2FMEC@200643|Bacteroidia,4AKN8@815|Bacteroidaceae	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CSH2_k127_2099228_1	1267211.KI669560_gene731	1.038e-128	420.0	COG1647@1|root,COG1647@2|Bacteria,4NHPY@976|Bacteroidetes,1IQS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,BAAT_C,Hydrolase_4
CSH2_k127_2099228_5	1123073.KB899241_gene2400	7.452e-18	84.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2099228_3	925409.KI911562_gene585	1.068e-78	264.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CSH2_k127_2099228_4	1123248.KB893319_gene4039	1.02e-62	218.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1ISJG@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CSH2_k127_2099228_0	1123248.KB893319_gene4038	6.901e-138	445.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1IQSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CSH2_k127_2099228_2	1267211.KI669560_gene302	1.729e-84	282.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CSH2_k127_2101723_0	926550.CLDAP_28490	5.195e-151	483.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	hoxF	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CSH2_k127_2101723_1	324602.Caur_1186	1.864e-84	286.0	COG3383@1|root,COG3383@2|Bacteria,2G65A@200795|Chloroflexi,3769N@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,NADH-G_4Fe-4S_3
CSH2_k127_2101723_2	926569.ANT_09670	4.83e-44	165.0	COG1941@1|root,COG1941@2|Bacteria,2G6MH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.12.1.2,1.8.98.5	ko:K14128,ko:K18007	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
CSH2_k127_2111941_0	1123248.KB893314_gene3481	4.368e-75	265.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,1IT7E@117747|Sphingobacteriia	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
CSH2_k127_2113632_0	266748.HY04_12590	5.05e-54	194.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,1HYYV@117743|Flavobacteriia,3ZPT8@59732|Chryseobacterium	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CSH2_k127_2113632_1	925409.KI911562_gene912	5.955e-40	150.0	COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,1IPPA@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
CSH2_k127_2114205_2	1122621.ATZA01000002_gene1568	1.05e-25	108.0	COG5642@1|root,COG5642@2|Bacteria,4NT6I@976|Bacteroidetes,1IZ43@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
CSH2_k127_2114205_1	1122621.ATZA01000002_gene1567	2.459e-43	164.0	COG5654@1|root,COG5654@2|Bacteria,4NTUP@976|Bacteroidetes,1IZ2I@117747|Sphingobacteriia	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
CSH2_k127_2114205_0	1239962.C943_04547	8.282e-132	430.0	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,47NA8@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CSH2_k127_2114205_3	700598.Niako_6582	1.973e-16	80.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1IRC3@117747|Sphingobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CSH2_k127_2117433_1	925409.KI911562_gene647	2.211e-217	679.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1IQJC@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CSH2_k127_2117433_0	929713.NIASO_17815	6.4e-323	1010.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1IQ0V@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
CSH2_k127_2118747_0	1267211.KI669560_gene2545	8.793e-182	572.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
CSH2_k127_2119454_0	700598.Niako_0710	1.611e-34	136.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1IPH9@117747|Sphingobacteriia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CSH2_k127_2119454_1	1121015.N789_09870	2.25e-13	79.0	2AQ4A@1|root,31F9J@2|Bacteria,1QCQH@1224|Proteobacteria,1T8GE@1236|Gammaproteobacteria,1XAMR@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2119454_2	1267211.KI669560_gene1931	2.353e-10	61.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1IQMR@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
CSH2_k127_212332_1	929713.NIASO_10735	3.577e-30	124.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1IQC4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
CSH2_k127_212332_0	925409.KI911562_gene22	5.454e-143	456.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CSH2_k127_2124570_1	761193.Runsl_5009	3.966e-26	111.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,47Q0U@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CSH2_k127_2124570_0	925409.KI911562_gene361	1.364e-93	316.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CSH2_k127_213052_0	700598.Niako_6781	6.061e-218	706.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,1IWJ0@117747|Sphingobacteriia	976|Bacteroidetes	H	COGs COG2192 carbamoyl transferase NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CSH2_k127_213052_1	760192.Halhy_2888	3.259e-46	192.0	COG0438@1|root,COG0438@2|Bacteria,4NI3I@976|Bacteroidetes,1IRMM@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_2130902_0	1122605.KB893636_gene3465	5.779e-252	783.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CSH2_k127_2134154_1	649349.Lbys_1229	5.769e-06	48.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47KNA@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CSH2_k127_2134154_0	700598.Niako_2568	3.352e-162	519.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IP63@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CSH2_k127_2144523_2	925409.KI911562_gene2899	2.535e-80	273.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1IW2E@117747|Sphingobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CSH2_k127_2144523_3	1313301.AUGC01000014_gene2454	1.924e-77	263.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CSH2_k127_2144523_0	700598.Niako_4497	1.446e-190	600.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1IP4B@117747|Sphingobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
CSH2_k127_2144523_1	925409.KI911562_gene2910	1.123e-99	328.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_2148384_1	1123248.KB893315_gene3133	1.836e-59	209.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CSH2_k127_2148384_0	925409.KI911562_gene254	1.322e-96	321.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1IYWB@117747|Sphingobacteriia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
CSH2_k127_2167720_0	509635.N824_00275	4.659e-77	268.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,1IVUW@117747|Sphingobacteriia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
CSH2_k127_2167720_1	1123248.KB893343_gene5	8.301e-60	209.0	COG4206@1|root,COG4206@2|Bacteria,4PKCR@976|Bacteroidetes,1J0WU@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_217508_0	1408473.JHXO01000006_gene1097	3.666e-86	297.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia	976|Bacteroidetes	CO	AhpC Tsa family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
CSH2_k127_217508_1	1453500.AT05_07905	2.644e-48	178.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,1I3D1@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CSH2_k127_217508_2	1347342.BN863_17060	2.339e-07	57.0	COG4461@1|root,COG4461@2|Bacteria,4NIBZ@976|Bacteroidetes,1I0CW@117743|Flavobacteriia	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PliI
CSH2_k127_2177105_1	1123248.KB893326_gene1279	4.886e-43	161.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
CSH2_k127_2177105_0	1267211.KI669560_gene2332	2.431e-118	384.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1IPWD@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CSH2_k127_218579_1	742767.HMPREF9456_02322	2.846e-27	117.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,2FPT2@200643|Bacteroidia,22YQF@171551|Porphyromonadaceae	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CSH2_k127_218579_0	1267211.KI669560_gene44	1.173e-156	500.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
CSH2_k127_2189570_0	1121875.KB907546_gene2689	7.813e-112	371.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PD40,Peptidase_S9
CSH2_k127_2189811_0	1189619.pgond44_14063	5.742e-08	65.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Reg_prop,Y_Y_Y
CSH2_k127_2194560_0	925409.KI911562_gene2996	3.207e-119	388.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1IP3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CSH2_k127_2194560_1	925409.KI911562_gene2995	1.334e-97	323.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,4NDUW@976|Bacteroidetes,1IQ7T@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
CSH2_k127_2194819_0	1239962.C943_01533	1.881e-115	379.0	28HUE@1|root,2Z815@2|Bacteria,4NHK5@976|Bacteroidetes,47P5G@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CSH2_k127_2196146_2	1123276.KB893250_gene349	9.597e-27	110.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_2196146_1	1123242.JH636434_gene5275	3.82e-144	471.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
CSH2_k127_2196146_0	929556.Solca_0540	9.201e-147	479.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,1IPD9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CSH2_k127_2199773_0	1267211.KI669560_gene2853	3.512e-107	352.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CSH2_k127_2207072_0	700598.Niako_5685	1.016e-181	573.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IRF8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC
CSH2_k127_2208752_2	925409.KI911562_gene892	4.888e-41	154.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1ISTG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated protein, GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2208752_1	925409.KI911562_gene893	6.614e-53	190.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1IT3W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CSH2_k127_2208752_3	700598.Niako_6587	8.664e-39	151.0	COG1286@1|root,COG1286@2|Bacteria,4P9DM@976|Bacteroidetes,1IZI5@117747|Sphingobacteriia	976|Bacteroidetes	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CSH2_k127_2208752_0	925409.KI911562_gene895	3.102e-82	274.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1INU7@117747|Sphingobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CSH2_k127_2215201_1	1121889.AUDM01000004_gene2634	9.348e-158	504.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia,2NTN7@237|Flavobacterium	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
CSH2_k127_2215201_2	1267211.KI669560_gene1635	3.487e-118	389.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CSH2_k127_2215201_0	1267211.KI669560_gene1636	6.774e-210	655.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1IQ1B@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome C oxidase subunit II, periplasmic domain	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CSH2_k127_2217737_0	1123248.KB893386_gene1986	2.886e-134	432.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CSH2_k127_2217737_1	1122225.AULQ01000010_gene152	7.431e-26	108.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CSH2_k127_2218499_1	1122605.KB893637_gene3288	3.357e-77	264.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CSH2_k127_2218499_2	1178825.ALIH01000005_gene241	1.563e-26	109.0	COG1476@1|root,COG1476@2|Bacteria,4NV53@976|Bacteroidetes,1I527@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
CSH2_k127_2218499_0	398720.MED217_17470	3.691e-91	306.0	COG0520@1|root,COG0520@2|Bacteria,4NM0W@976|Bacteroidetes,1I00M@117743|Flavobacteriia,2XJWU@283735|Leeuwenhoekiella	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CSH2_k127_2222585_0	929556.Solca_1039	8.956e-38	143.0	COG0521@1|root,COG0521@2|Bacteria,4NHNF@976|Bacteroidetes,1IP72@117747|Sphingobacteriia	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
CSH2_k127_2222585_1	1270196.JCKI01000001_gene3899	4.902e-06	57.0	2A2ZH@1|root,30RE0@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
CSH2_k127_2224452_0	700598.Niako_6992	9.226e-169	540.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_2224452_1	700598.Niako_3484	3.766e-46	170.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1ITU7@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CSH2_k127_2228491_1	1089547.KB913013_gene2444	1.3e-19	94.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,47MKM@768503|Cytophagia	976|Bacteroidetes	O	PFAM Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
CSH2_k127_2228491_0	1123248.KB893331_gene3763	2.502e-91	305.0	COG3531@1|root,COG3531@2|Bacteria,4NQKI@976|Bacteroidetes,1IXJ5@117747|Sphingobacteriia	976|Bacteroidetes	O	Protein-disulfide isomerase	dsbC	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	DSBA,Thioredoxin_5
CSH2_k127_2228491_2	700598.Niako_1866	1.796e-17	84.0	COG1105@1|root,COG1105@2|Bacteria,4NFZI@976|Bacteroidetes,1IR0I@117747|Sphingobacteriia	976|Bacteroidetes	G	belongs to the carbohydrate kinase PfkB family	pfkB	-	2.7.1.11,2.7.1.144	ko:K00917,ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CSH2_k127_2229649_0	762903.Pedsa_2028	5.876e-32	139.0	COG2207@1|root,COG2207@2|Bacteria,4NTZ2@976|Bacteroidetes,1IXMS@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CSH2_k127_2238901_1	929713.NIASO_19625	1.589e-47	171.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1INM0@117747|Sphingobacteriia	976|Bacteroidetes	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CSH2_k127_2238901_0	1123277.KB893173_gene1781	1.069e-55	203.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,47NYB@768503|Cytophagia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
CSH2_k127_2242930_0	925409.KI911562_gene202	1.714e-200	632.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CSH2_k127_2246942_0	925409.KI911562_gene2046	1.412e-71	244.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CSH2_k127_2246942_1	1123248.KB893316_gene4531	2.051e-57	205.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1IQ5D@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CSH2_k127_2247009_0	1121889.AUDM01000016_gene2080	3.936e-139	447.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1HY05@117743|Flavobacteriia,2NSRK@237|Flavobacterium	976|Bacteroidetes	G	Alpha-glucosidase	-	-	3.2.1.20,3.2.1.3	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01790,R01791,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31,GH97	-	GH97_C,GH97_N,Glyco_hydro_97
CSH2_k127_2247009_1	700598.Niako_6029	3.566e-122	395.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CSH2_k127_2249528_0	1121481.AUAS01000009_gene3	1.864e-113	377.0	COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,47NQE@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294,ko:K03758	-	-	-	-	ko00000,ko02000	2.A.3.2	-	-	AA_permease_2
CSH2_k127_2250752_1	1434325.AZQN01000001_gene665	1.618e-41	154.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CSH2_k127_2250752_0	388413.ALPR1_08308	9.7e-250	776.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CSH2_k127_2250752_3	1123248.KB893324_gene1683	8.436e-25	106.0	COG0607@1|root,COG0607@2|Bacteria,4NUN5@976|Bacteroidetes,1J07C@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CSH2_k127_2250752_2	755732.Fluta_3524	1.87e-31	125.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia,2PC1E@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CSH2_k127_2271293_0	1434325.AZQN01000004_gene1834	3.954e-74	261.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47NEB@768503|Cytophagia	976|Bacteroidetes	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
CSH2_k127_2274443_1	700598.Niako_5481	9.947e-77	264.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CSH2_k127_2274443_0	1123248.KB893348_gene356	0.0	1536.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CSH2_k127_2275550_1	1235813.JCM10003_2930	4.045e-31	124.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,2FMEC@200643|Bacteroidia,4AKN8@815|Bacteroidaceae	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CSH2_k127_2275550_0	925409.KI911562_gene2539	7.014e-54	200.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CSH2_k127_2279810_1	1248917.ANFX01000013_gene1508	3.141e-10	66.0	2EQH5@1|root,33I35@2|Bacteria,1N2B2@1224|Proteobacteria,2UDX4@28211|Alphaproteobacteria,2K4K4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2279810_0	700598.Niako_4625	1.901e-55	203.0	COG2114@1|root,COG2207@1|root,COG2114@2|Bacteria,COG2207@2|Bacteria,4NFVC@976|Bacteroidetes,1IXZX@117747|Sphingobacteriia	976|Bacteroidetes	K	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242,HTH_18
CSH2_k127_2280902_0	1122176.KB903598_gene4758	7.56e-120	394.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1IPDM@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CSH2_k127_2290485_1	700598.Niako_1610	4.036e-95	315.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CSH2_k127_2290485_0	1279009.ADICEAN_02472	3.789e-182	575.0	COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,47K95@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CSH2_k127_229888_0	1122605.KB893648_gene3589	3.862e-234	732.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1IQV0@117747|Sphingobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CSH2_k127_229888_1	925409.KI911562_gene2138	5.051e-56	198.0	COG1179@1|root,COG1179@2|Bacteria,4NEKB@976|Bacteroidetes,1IPIM@117747|Sphingobacteriia	976|Bacteroidetes	H	ThiF family	tcdA	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
CSH2_k127_2304302_0	1128912.GMES_1004	1.037e-71	255.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,465BK@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CSH2_k127_2311476_0	714943.Mucpa_5141	2.341e-97	324.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1IQXC@117747|Sphingobacteriia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
CSH2_k127_2311476_1	1121373.KB903643_gene3421	1.057e-77	262.0	COG2334@1|root,COG2334@2|Bacteria,4NITA@976|Bacteroidetes,47M89@768503|Cytophagia	976|Bacteroidetes	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2316109_1	376686.Fjoh_3297	7.64e-20	93.0	COG5295@1|root,COG5295@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia,2NUIA@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2316109_0	471854.Dfer_3344	1.804e-34	145.0	COG2911@1|root,COG2911@2|Bacteria,4PKFD@976|Bacteroidetes,47S1V@768503|Cytophagia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CSH2_k127_2316109_2	1185876.BN8_00055	2.33e-19	96.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_231927_0	1121288.AULL01000011_gene1078	4.514e-187	589.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,1I067@117743|Flavobacteriia,3ZNS9@59732|Chryseobacterium	976|Bacteroidetes	E	Beta-eliminating lyase	tpl	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
CSH2_k127_2324701_0	714943.Mucpa_5102	2.356e-58	212.0	COG0156@1|root,COG0156@2|Bacteria,4NKC1@976|Bacteroidetes,1IS9B@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CSH2_k127_2334905_0	1267211.KI669560_gene2069	1.782e-70	254.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPAB@117747|Sphingobacteriia	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
CSH2_k127_2341727_0	1123037.AUDE01000005_gene3088	1.92e-92	317.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
CSH2_k127_2345849_1	700598.Niako_6623	3.779e-70	240.0	COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_2345849_0	700598.Niako_5743	4.324e-96	327.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes,1IPAQ@117747|Sphingobacteriia	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CSH2_k127_2359373_0	760192.Halhy_4972	7.275e-63	222.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1IPI2@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_2362610_1	700598.Niako_2798	1.205e-31	132.0	COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,4NKED@976|Bacteroidetes,1ITWK@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
CSH2_k127_2362610_0	700598.Niako_4749	8.121e-41	160.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CSH2_k127_2363008_0	761193.Runsl_2526	2.391e-67	233.0	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,47PW5@768503|Cytophagia	976|Bacteroidetes	G	MGS-like domain	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
CSH2_k127_2365941_1	411154.GFO_2002	2.408e-65	229.0	COG0438@1|root,COG0438@2|Bacteria,4NGYT@976|Bacteroidetes,1HYZ0@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CSH2_k127_2365941_0	700598.Niako_5344	1.723e-69	249.0	COG0438@1|root,COG0438@2|Bacteria,4NJR3@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_2370791_0	1123278.KB893600_gene2774	4.334e-82	279.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CSH2_k127_2370791_1	760192.Halhy_0634	7.407e-65	231.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IW1C@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_2376471_1	1121875.KB907556_gene612	9.913e-30	122.0	2E5SP@1|root,330H2@2|Bacteria,4P4B3@976|Bacteroidetes	976|Bacteroidetes	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
CSH2_k127_2376471_2	1123037.AUDE01000023_gene2809	4.14e-09	64.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2
CSH2_k127_2376471_0	1239962.C943_03699	1.732e-124	406.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CSH2_k127_2379781_0	1296416.JACB01000029_gene4195	2.374e-73	273.0	COG3291@1|root,COG3291@2|Bacteria,4NI5F@976|Bacteroidetes,1I8AC@117743|Flavobacteriia,2YK1N@290174|Aquimarina	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,PKD
CSH2_k127_2381140_1	1453500.AT05_02475	8.339e-06	49.0	COG0640@1|root,COG0640@2|Bacteria,4NS23@976|Bacteroidetes,1I40U@117743|Flavobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
CSH2_k127_2381140_0	649349.Lbys_2718	2.164e-132	426.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47JS2@768503|Cytophagia	976|Bacteroidetes	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CSH2_k127_2383780_1	925409.KI911562_gene182	8.79e-61	212.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1INMV@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CSH2_k127_2383780_0	1267211.KI669560_gene464	3.101e-132	433.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes	976|Bacteroidetes	P	Transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CSH2_k127_2384093_0	1239962.C943_02423	4.035e-209	656.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47MT5@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CSH2_k127_238766_0	1121887.AUDK01000023_gene3473	1.566e-112	374.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia,2NW6Q@237|Flavobacterium	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CSH2_k127_238766_1	1120966.AUBU01000005_gene3626	1.829e-59	210.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
CSH2_k127_238766_2	1239962.C943_03759	1.374e-39	152.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CSH2_k127_2387695_0	925409.KI911562_gene2304	1.868e-94	314.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_2387695_1	1305737.JAFX01000001_gene2187	5.108e-43	160.0	COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes,47U9R@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2390297_0	925409.KI911562_gene868	2.641e-111	363.0	COG4947@1|root,COG4947@2|Bacteria,4NJWM@976|Bacteroidetes,1IVCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CSH2_k127_2390297_1	1122605.KB893643_gene532	2.112e-23	108.0	2C85M@1|root,31482@2|Bacteria,4NSY2@976|Bacteroidetes,1IUAG@117747|Sphingobacteriia	976|Bacteroidetes	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CSH2_k127_2395018_0	593750.Metfor_1047	5.053e-64	229.0	arCOG09580@1|root,arCOG09580@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2402085_1	991.IW20_23070	4.516e-05	53.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWKW@117743|Flavobacteriia,2NTRY@237|Flavobacterium	976|Bacteroidetes	P	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region, TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_2402085_0	485918.Cpin_1233	9.896e-55	193.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CSH2_k127_240703_0	1500281.JQKZ01000005_gene4012	1.917e-39	151.0	COG3409@1|root,COG3409@2|Bacteria,4P2ER@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl hydrolase family 46	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_46
CSH2_k127_2415946_3	1123248.KB893318_gene4148	6.937e-24	115.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
CSH2_k127_2415946_4	1121011.AUCB01000016_gene3974	8.183e-07	57.0	2DTH4@1|root,33KAP@2|Bacteria,4NYZ8@976|Bacteroidetes,1IBJQ@117743|Flavobacteriia,23IDD@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2415946_0	700598.Niako_3671	1.306e-147	479.0	COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,1IPQN@117747|Sphingobacteriia	976|Bacteroidetes	EG	COGs COG2610 H gluconate symporter and related permease	gntT	-	-	ko:K06155	-	-	-	-	ko00000,ko02000	2.A.8.1.4	-	-	GntP_permease
CSH2_k127_2415946_1	1250278.JQNQ01000001_gene31	1.321e-121	402.0	COG0362@1|root,COG3265@1|root,COG0362@2|Bacteria,COG3265@2|Bacteria,4NG05@976|Bacteroidetes,1HXYX@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2,SKI
CSH2_k127_2417764_0	1123248.KB893337_gene2579	6.693e-170	535.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CSH2_k127_2417764_1	925409.KI911562_gene2348	4.62e-76	257.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CSH2_k127_2424103_1	700598.Niako_1570	1.8e-22	104.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,1IS3N@117747|Sphingobacteriia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
CSH2_k127_2424103_0	1121912.AUHD01000001_gene2743	1.252e-35	142.0	COG4538@1|root,COG4538@2|Bacteria,4PKKQ@976|Bacteroidetes,1HYE5@117743|Flavobacteriia	976|Bacteroidetes	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SnoaL_2
CSH2_k127_2424510_0	1267211.KI669560_gene1251	1.604e-150	484.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1IPDB@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
CSH2_k127_2424510_1	1121895.Q765_02010	6.464e-06	51.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia,2NSZ6@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
CSH2_k127_2427195_0	879212.DespoDRAFT_02289	1.892e-102	337.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,42MR4@68525|delta/epsilon subdivisions,2WM3M@28221|Deltaproteobacteria,2MMW9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
CSH2_k127_2427195_1	946483.Cenrod_0235	4.854e-09	69.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2VVW1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7
CSH2_k127_2429155_0	925409.KI911562_gene274	2.541e-86	289.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,1IPWE@117747|Sphingobacteriia	976|Bacteroidetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ,PQQ_2,PQQ_3
CSH2_k127_2429155_1	1122605.KB893626_gene2627	2.263e-74	254.0	COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,1J0RH@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CSH2_k127_2443138_0	1267211.KI669560_gene1248	3.83e-135	443.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1IPKS@117747|Sphingobacteriia	976|Bacteroidetes	S	Ragb susd	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_2443138_1	525373.HMPREF0766_12936	2.013e-22	98.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IP84@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_2444492_1	1123248.KB893326_gene1441	5.231e-37	140.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
CSH2_k127_2444492_0	1123248.KB893326_gene1441	1.126e-66	233.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
CSH2_k127_2444492_2	468059.AUHA01000005_gene2445	7.978e-33	130.0	COG2149@1|root,COG2149@2|Bacteria,4NW0X@976|Bacteroidetes,1IZG7@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
CSH2_k127_2444492_3	1267211.KI669560_gene2213	1.303e-15	77.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,1INMM@117747|Sphingobacteriia	976|Bacteroidetes	S	iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
CSH2_k127_2444985_0	925409.KI911562_gene1618	1.051e-164	524.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1INYI@117747|Sphingobacteriia	976|Bacteroidetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CSH2_k127_2444985_1	700598.Niako_5473	4.757e-81	271.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1INU0@117747|Sphingobacteriia	976|Bacteroidetes	F	deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
CSH2_k127_2447015_0	700598.Niako_6695	3.452e-100	336.0	28K2C@1|root,2Z9RQ@2|Bacteria,4NJP3@976|Bacteroidetes,1ITQ3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2448140_2	580340.Tlie_0365	4.968e-05	51.0	COG0457@1|root,COG0457@2|Bacteria	580340.Tlie_0365|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2448140_0	688270.Celal_2946	6.439e-78	266.0	COG3647@1|root,COG3647@2|Bacteria,4NMNV@976|Bacteroidetes,1I1B4@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
CSH2_k127_2448140_1	1123248.KB893322_gene595	5.975e-37	141.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1INS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CSH2_k127_2448509_0	929713.NIASO_13035	2.074e-180	570.0	COG1297@1|root,COG1297@2|Bacteria,4NEIY@976|Bacteroidetes,1IP8J@117747|Sphingobacteriia	976|Bacteroidetes	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
CSH2_k127_2451520_0	1121451.DESAM_21610	5.429e-150	486.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
CSH2_k127_2453557_1	1267211.KI669560_gene2542	1.937e-135	435.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_2453557_0	1123248.KB893323_gene1623	1.301e-147	473.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CSH2_k127_2480261_1	1270196.JCKI01000005_gene3144	2.79e-09	61.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IS8Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	LAB_N,PMT,PMT_2
CSH2_k127_2480261_0	247490.KSU1_C0449	3.671e-37	157.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
CSH2_k127_2488736_0	700598.Niako_4468	3.748e-142	458.0	COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CSH2_k127_2496467_0	1229172.JQFA01000004_gene1481	1.257e-114	378.0	COG5361@1|root,COG5361@2|Bacteria,1G49Q@1117|Cyanobacteria,1H9SH@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
CSH2_k127_2496467_1	1189620.AJXL01000065_gene3630	1.247e-48	181.0	COG2335@1|root,COG2335@2|Bacteria,4NVI8@976|Bacteroidetes,1I598@117743|Flavobacteriia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CSH2_k127_2496784_0	1267211.KI669560_gene2684	2.29e-37	149.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1IQXN@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CSH2_k127_2496784_1	485918.Cpin_7030	6.451e-37	144.0	COG4232@1|root,COG4232@2|Bacteria,4NQID@976|Bacteroidetes,1ISZ1@117747|Sphingobacteriia	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CSH2_k127_2498690_1	1296415.JACC01000042_gene112	5.337e-22	96.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1HXMD@117743|Flavobacteriia,2YIIH@290174|Aquimarina	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2498690_0	1123248.KB893348_gene193	2.849e-50	184.0	COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CSH2_k127_2499629_0	880070.Cycma_4553	2.15e-125	411.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,4NM18@976|Bacteroidetes,47XKA@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
CSH2_k127_2500765_1	1121889.AUDM01000019_gene84	2.547e-73	252.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1HZ60@117743|Flavobacteriia,2NUHU@237|Flavobacterium	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CSH2_k127_2500765_0	700598.Niako_2149	2.156e-219	686.0	COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1IP6Q@117747|Sphingobacteriia	976|Bacteroidetes	G	glucose-1-phosphate adenylyltransferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CSH2_k127_2500765_2	1453500.AT05_10770	5.219e-36	138.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
CSH2_k127_2501390_0	1122605.KB893644_gene1517	4.59e-236	741.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CSH2_k127_2501797_0	886377.Murru_2930	6.881e-12	74.0	2AVE1@1|root,31M5W@2|Bacteria,4NS2G@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2501797_1	700598.Niako_3552	1.79e-05	53.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IVSZ@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0553 Superfamily II DNA RNA helicase SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
CSH2_k127_2505015_2	471854.Dfer_3644	3.05e-15	76.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,47KF3@768503|Cytophagia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CSH2_k127_2505015_1	760192.Halhy_2813	5.165e-59	207.0	COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,1IS1P@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CSH2_k127_2505015_0	1123277.KB893195_gene5705	2.215e-61	216.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,47M1G@768503|Cytophagia	976|Bacteroidetes	E	alanine racemase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
CSH2_k127_2509902_1	714943.Mucpa_5909	1.019e-63	220.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1IQCT@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CSH2_k127_2509902_0	925409.KI911562_gene1077	1.247e-98	324.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1IQCT@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CSH2_k127_2516773_1	485918.Cpin_0949	1.043e-25	111.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CSH2_k127_2516773_0	1123248.KB893386_gene1829	9.247e-273	846.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CSH2_k127_2517930_1	1267211.KI669560_gene2012	1.998e-66	232.0	COG1629@1|root,COG1629@2|Bacteria,4NMUQ@976|Bacteroidetes,1IS0V@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
CSH2_k127_2517930_0	1267211.KI669560_gene2447	3.583e-144	462.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1IQTZ@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CSH2_k127_2530804_0	1338011.BD94_1974	1.02e-59	208.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,1HXFV@117743|Flavobacteriia,34PM3@308865|Elizabethkingia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
CSH2_k127_2533725_0	925409.KI911562_gene211	1.799e-141	451.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR4T@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CSH2_k127_2533725_2	1123248.KB893314_gene3401	4.492e-77	261.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1ISEW@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CSH2_k127_2533725_1	925409.KI911562_gene213	9.464e-95	310.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CSH2_k127_2536178_0	1267211.KI669560_gene1259	4.638e-195	619.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1INYW@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CSH2_k127_2536537_1	1122605.KB893626_gene2587	8.855e-66	237.0	COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1INPT@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
CSH2_k127_2536537_0	1123248.KB893359_gene2066	4.359e-146	468.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1IP9F@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CSH2_k127_2536537_2	1267211.KI669560_gene2092	1.017e-42	158.0	COG0189@1|root,COG0189@2|Bacteria,4NFK1@976|Bacteroidetes,1IR39@117747|Sphingobacteriia	976|Bacteroidetes	HJ	Glutathione synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2542320_3	992406.RIA_1798	1.099e-37	145.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,1I2YA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CSH2_k127_2542320_2	925409.KI911562_gene1607	3.392e-61	233.0	COG0810@1|root,COG0860@1|root,COG4219@1|root,COG0810@2|Bacteria,COG0860@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1IXPP@117747|Sphingobacteriia	976|Bacteroidetes	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Peptidase_M56,TonB_C
CSH2_k127_2542320_4	1121904.ARBP01000013_gene354	1.086e-19	104.0	COG3292@1|root,COG4219@1|root,COG3292@2|Bacteria,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CSH2_k127_2542320_0	700598.Niako_6638	7.472e-101	344.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1INKX@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CSH2_k127_2542320_1	1434325.AZQN01000004_gene1778	2.116e-72	249.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,47JBH@768503|Cytophagia	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CSH2_k127_2547127_2	485918.Cpin_2021	2.036e-18	85.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1IQ61@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	tdh	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CSH2_k127_2547127_0	1267211.KI669560_gene2469	1.212e-115	377.0	COG0204@1|root,COG0204@2|Bacteria,4NG70@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CSH2_k127_2547127_1	1123248.KB893381_gene1038	2.024e-66	232.0	COG0637@1|root,COG0637@2|Bacteria,4NID6@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
CSH2_k127_2548566_0	925409.KI911562_gene2380	2.613e-48	181.0	COG3409@1|root,COG3409@2|Bacteria,4P38H@976|Bacteroidetes	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CSH2_k127_2548566_1	1296416.JACB01000029_gene4190	3.534e-23	103.0	COG0464@1|root,COG0464@2|Bacteria,4NFWG@976|Bacteroidetes,1HZA4@117743|Flavobacteriia,2YI1T@290174|Aquimarina	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CSH2_k127_2550154_1	1550091.JROE01000002_gene715	9.938e-105	342.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,1IPGE@117747|Sphingobacteriia	976|Bacteroidetes	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
CSH2_k127_2550154_0	1239962.C943_00987	3.071e-108	353.0	COG0252@1|root,COG0252@2|Bacteria,4NFKG@976|Bacteroidetes,47MY9@768503|Cytophagia	976|Bacteroidetes	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CSH2_k127_2553260_0	1166018.FAES_5278	2.285e-61	220.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,47NSK@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
CSH2_k127_2559761_0	32057.KB217478_gene615	4.336e-93	319.0	COG0154@1|root,COG0154@2|Bacteria,1G1H1@1117|Cyanobacteria,1HSHH@1161|Nostocales	1117|Cyanobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426,ko:K21801	ko00330,ko00360,ko00380,ko00627,ko00643,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map01100,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CSH2_k127_2564096_0	1500281.JQKZ01000005_gene4117	8.187e-52	188.0	COG2318@1|root,COG2318@2|Bacteria,4NNRD@976|Bacteroidetes,1I4R2@117743|Flavobacteriia,3ZRAI@59732|Chryseobacterium	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CSH2_k127_2564096_1	1203611.KB894547_gene2716	3.124e-33	134.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,2FNHK@200643|Bacteroidia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CSH2_k127_2565521_0	1267211.KI669560_gene1276	1.465e-153	492.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CSH2_k127_2565562_1	485918.Cpin_0239	6.271e-37	143.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1INKY@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CSH2_k127_2565562_0	485918.Cpin_0678	5.594e-86	290.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CSH2_k127_2566816_0	700598.Niako_4718	1.499e-153	489.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1INRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
CSH2_k127_2576917_0	504472.Slin_4417	1.082e-13	80.0	COG0810@1|root,COG2849@1|root,COG0810@2|Bacteria,COG2849@2|Bacteria,4NU09@976|Bacteroidetes,47NSU@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
CSH2_k127_2580890_1	925409.KI911562_gene805	2.993e-20	91.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1IQ1H@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
CSH2_k127_2580890_0	1123248.KB893385_gene4794	1.422e-84	288.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1IRKW@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the precorrin methyltransferase family	cysG	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,NAD_binding_7,Porphobil_deam,TP_methylase
CSH2_k127_2584710_1	929713.NIASO_10060	7.906e-113	368.0	COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1IP90@117747|Sphingobacteriia	976|Bacteroidetes	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CSH2_k127_2584710_0	485918.Cpin_0917	1.414e-223	697.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IPSM@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CSH2_k127_2588111_1	925409.KI911562_gene1895	1.544e-70	253.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPAB@117747|Sphingobacteriia	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
CSH2_k127_2588111_2	457424.BFAG_02285	3.541e-32	128.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,2FTD1@200643|Bacteroidia,4ARAM@815|Bacteroidaceae	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CSH2_k127_2588111_0	1267211.KI669560_gene1169	5.945e-295	908.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CSH2_k127_2588111_3	700598.Niako_5514	1.126e-28	117.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1ITVV@117747|Sphingobacteriia	976|Bacteroidetes	C	ATP synthase	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CSH2_k127_2588111_4	700598.Niako_7308	4.346e-07	54.0	28N4A@1|root,2ZB9T@2|Bacteria,4NKZG@976|Bacteroidetes	976|Bacteroidetes	S	COG NOG26965 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CSH2_k127_2588426_0	1123248.KB893337_gene2591	1.382e-102	346.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,1IRMB@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_2588426_1	925409.KI911562_gene1896	5.445e-57	204.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1IRU4@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CSH2_k127_2592434_1	1123248.KB893385_gene4872	4.738e-241	767.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
CSH2_k127_2592434_0	925409.KI911562_gene1619	2.681e-248	775.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CSH2_k127_2602815_0	1267211.KI669560_gene348	3.313e-269	835.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVNR@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_2607525_0	1123248.KB893315_gene3158	1.379e-167	529.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CSH2_k127_2612719_0	1123248.KB893386_gene1980	1.257e-103	346.0	COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,1IQB7@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CSH2_k127_2612719_1	700598.Niako_7327	1.542e-23	106.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1IR5B@117747|Sphingobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CSH2_k127_2622630_0	391596.PBAL39_00677	1.004e-110	368.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,1IPKI@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	bfce	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CSH2_k127_2622630_1	1434325.AZQN01000008_gene2893	3.56e-76	262.0	COG2755@1|root,COG2755@2|Bacteria,4NHWJ@976|Bacteroidetes,47NGU@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CSH2_k127_2625700_1	1122605.KB893625_gene1736	1.455e-15	76.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1IQ61@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	tdh	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CSH2_k127_2625700_0	925409.KI911562_gene2955	6.813e-129	416.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1IQ2W@117747|Sphingobacteriia	976|Bacteroidetes	M	2-dehydro-3-deoxyphosphooctonate aldolase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CSH2_k127_2625700_2	1121859.KB890738_gene3385	7e-12	65.0	28KYY@1|root,2ZAEA@2|Bacteria,4NQHX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2631690_0	391596.PBAL39_22872	3.158e-127	415.0	COG3934@1|root,COG3934@2|Bacteria,4NGQC@976|Bacteroidetes,1IWH2@117747|Sphingobacteriia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
CSH2_k127_2632696_1	1122605.KB893645_gene1209	1.362e-40	151.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1IV0I@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CSH2_k127_2632696_0	925409.KI911562_gene2106	4.005e-49	177.0	COG0731@1|root,COG0731@2|Bacteria,4PNUE@976|Bacteroidetes,1J0SJ@117747|Sphingobacteriia	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CSH2_k127_2645933_2	1239962.C943_01576	3.091e-103	344.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,47NFE@768503|Cytophagia	976|Bacteroidetes	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CSH2_k127_2645933_0	1123248.KB893314_gene3370	6.885e-141	477.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
CSH2_k127_2645933_3	1454007.JAUG01000036_gene4361	2.829e-34	144.0	COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,1IS30@117747|Sphingobacteriia	976|Bacteroidetes	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CSH2_k127_2645933_1	742766.HMPREF9455_01055	1.838e-105	358.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,2FNVI@200643|Bacteroidia,22WSY@171551|Porphyromonadaceae	976|Bacteroidetes	G	Alpha amylase, catalytic domain protein	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,DUF3459,Malt_amylase_C
CSH2_k127_2656492_2	946077.W5A_06426	5.678e-22	98.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,1II9B@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CSH2_k127_2656492_1	700598.Niako_4053	6.253e-48	178.0	COG5263@1|root,COG5263@2|Bacteria,4PN8Y@976|Bacteroidetes,1J0PQ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
CSH2_k127_2656492_0	1408813.AYMG01000004_gene4588	4.862e-56	202.0	COG2017@1|root,COG2017@2|Bacteria,4NMWB@976|Bacteroidetes,1IPFY@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
CSH2_k127_2662468_0	1296415.JACC01000014_gene984	9.5e-99	336.0	COG0739@1|root,COG2273@1|root,COG3401@1|root,COG0739@2|Bacteria,COG2273@2|Bacteria,COG3401@2|Bacteria,4P1G2@976|Bacteroidetes,1I78P@117743|Flavobacteriia,2YKT3@290174|Aquimarina	976|Bacteroidetes	G	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2666001_1	1267211.KI669560_gene1040	3.198e-57	201.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1IT1Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CSH2_k127_2666001_0	1123248.KB893316_gene4645	7.166e-61	213.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IVSZ@117747|Sphingobacteriia	976|Bacteroidetes	L	COGs COG0553 Superfamily II DNA RNA helicase SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
CSH2_k127_2675759_2	909663.KI867151_gene3085	1.253e-05	53.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WMCV@28221|Deltaproteobacteria,2MQYF@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CSH2_k127_2675759_0	1123248.KB893386_gene1944	2.773e-121	398.0	COG3266@1|root,COG3266@2|Bacteria,4NFRK@976|Bacteroidetes,1IUYF@117747|Sphingobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2675759_1	925409.KI911562_gene442	9.609e-43	159.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_2676175_1	1122605.KB893627_gene3022	4.589e-62	217.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1IRXQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CSH2_k127_2676175_0	1123248.KB893331_gene3749	7.37e-183	582.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1IPI0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_2677870_0	925409.KI911562_gene1677	2.347e-77	265.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1J0TI@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_2677870_1	1124780.ANNU01000025_gene3410	5.498e-66	230.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CSH2_k127_2682822_1	925409.KI911562_gene1196	1.158e-63	225.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CSH2_k127_2682822_2	700598.Niako_6898	1.311e-54	194.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CSH2_k127_2684562_1	485918.Cpin_6300	5.135e-20	105.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1INZH@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CSH2_k127_2684562_0	700598.Niako_0569	1.083e-112	368.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1IR2F@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
CSH2_k127_2686190_2	1236514.BAKL01000069_gene4404	3.166e-33	135.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,2FM9N@200643|Bacteroidia,4AKDF@815|Bacteroidaceae	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	bfce	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CSH2_k127_2686190_1	1124780.ANNU01000006_gene2796	5.39e-187	591.0	COG2152@1|root,COG2152@2|Bacteria,4NGA2@976|Bacteroidetes,47M2J@768503|Cytophagia	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
CSH2_k127_2686190_0	1121887.AUDK01000003_gene2776	8.109e-211	666.0	COG2211@1|root,COG2211@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia,2NUNM@237|Flavobacterium	976|Bacteroidetes	G	MFS/sugar transport protein	yicJ_1	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CSH2_k127_2686371_0	925409.KI911562_gene2792	3.053e-125	410.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1IQ18@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CSH2_k127_2686371_1	1089547.KB913013_gene1247	7.36e-22	108.0	COG3502@1|root,COG3502@2|Bacteria,4NV0K@976|Bacteroidetes,47SFX@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
CSH2_k127_2690895_0	1123248.KB893321_gene540	4.936e-166	538.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
CSH2_k127_2693713_1	313606.M23134_01965	6.748e-22	106.0	2F6UW@1|root,33ZB0@2|Bacteria,4P44P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2693713_0	1122605.KB893625_gene1792	1.827e-40	154.0	COG1280@1|root,COG1280@2|Bacteria,4NUV7@976|Bacteroidetes,1IUGQ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CSH2_k127_2696736_1	1120965.AUBV01000004_gene734	1.882e-31	126.0	COG0366@1|root,COG0366@2|Bacteria,4NI8U@976|Bacteroidetes,47XJK@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
CSH2_k127_2696736_0	1279009.ADICEAN_03560	2.862e-132	432.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,47JIF@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase 97	-	-	3.2.1.20,3.2.1.3	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01790,R01791,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31,GH97	-	GH97_C,GH97_N,Glyco_hydro_97
CSH2_k127_2697833_1	761193.Runsl_0267	3.035e-42	163.0	COG3548@1|root,COG3548@2|Bacteria,4NPIF@976|Bacteroidetes,47R96@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
CSH2_k127_2697833_0	929562.Emtol_3443	1.405e-123	400.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,47KN8@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
CSH2_k127_2706352_0	1267211.KI669560_gene2360	1.17e-196	615.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1IPW2@117747|Sphingobacteriia	976|Bacteroidetes	GM	NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CSH2_k127_2709749_1	1046627.BZARG_1432	7.635e-12	68.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,1I0ZQ@117743|Flavobacteriia	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
CSH2_k127_2709749_0	1123248.KB893314_gene3584	4.84e-322	1001.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1IPB3@117747|Sphingobacteriia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CSH2_k127_2711055_0	1123248.KB893315_gene2995	2.629e-166	528.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1IP14@117747|Sphingobacteriia	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
CSH2_k127_2712339_0	1454007.JAUG01000047_gene524	1.597e-191	607.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1IQ6C@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM coagulation factor 5 8 type	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C
CSH2_k127_2712339_1	700598.Niako_5804	1.276e-139	449.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1IW51@117747|Sphingobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
CSH2_k127_2714730_2	760192.Halhy_3252	4.866e-20	90.0	COG2337@1|root,COG2337@2|Bacteria,4P9NI@976|Bacteroidetes,1IZYP@117747|Sphingobacteriia	976|Bacteroidetes	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CSH2_k127_2714730_3	1189612.A33Q_1755	1.221e-18	87.0	2EA6H@1|root,334B9@2|Bacteria,4NUWX@976|Bacteroidetes,47X36@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2714730_1	1123248.KB893385_gene4769	1.101e-27	120.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1IUC4@117747|Sphingobacteriia	976|Bacteroidetes	J	Class I peptide chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CSH2_k127_2714730_0	700598.Niako_2957	4.132e-53	198.0	2DNNM@1|root,32YAS@2|Bacteria,4NVE7@976|Bacteroidetes,1IZ48@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2717314_0	1122605.KB893644_gene1375	4.499e-69	241.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CSH2_k127_2717314_1	1249975.JQLP01000005_gene1599	2.599e-21	100.0	2EFCX@1|root,3395T@2|Bacteria,4NXAJ@976|Bacteroidetes,1ICMG@117743|Flavobacteriia,2P61F@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2717873_0	700598.Niako_6570	1.032e-149	476.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1INVN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CSH2_k127_2717873_1	1189612.A33Q_2629	1.972e-48	192.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CSH2_k127_2722216_0	1123248.KB893332_gene2266	1.262e-140	467.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
CSH2_k127_2723414_0	700598.Niako_6407	6.832e-303	938.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1IQ8E@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CSH2_k127_2723414_2	925409.KI911562_gene925	3.415e-96	321.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1INUR@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CSH2_k127_2723414_4	925409.KI911562_gene925	7.873e-30	120.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1INUR@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CSH2_k127_2723414_1	700598.Niako_6410	4.115e-162	517.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CSH2_k127_2723414_3	700598.Niako_6413	8.556e-56	197.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1IP0R@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_2728549_0	1120966.AUBU01000008_gene2384	2.363e-45	174.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
CSH2_k127_2733378_0	1123248.KB893359_gene2117	3.515e-114	371.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_2733378_2	925409.KI911562_gene96	2.104e-77	262.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1IRY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CSH2_k127_2733378_1	1123248.KB893314_gene3586	1.077e-92	308.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CSH2_k127_2734298_0	925409.KI911562_gene1095	6.834e-148	479.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1INPG@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2812 DNA polymerase III, gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
CSH2_k127_2734298_1	925409.KI911562_gene1096	1.595e-76	259.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1ISUU@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CSH2_k127_2734731_1	1123248.KB893319_gene4021	9.932e-32	126.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1IRFR@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CSH2_k127_2734731_0	485918.Cpin_1305	3.087e-88	295.0	COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CSH2_k127_2736725_0	1267211.KI669560_gene1024	1.702e-204	647.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IWKA@117747|Sphingobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
CSH2_k127_2736754_0	700598.Niako_0329	1.694e-102	336.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1IR18@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CSH2_k127_2736754_1	929713.NIASO_02175	2.901e-70	242.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1INM6@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CSH2_k127_2739851_1	929556.Solca_1050	9.428e-139	448.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1IRDG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_2739851_0	700598.Niako_4356	5.037e-151	492.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CSH2_k127_2743751_2	468059.AUHA01000002_gene107	2.927e-29	119.0	COG0457@1|root,COG4191@1|root,COG0457@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1IQBI@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12
CSH2_k127_2743751_0	1202532.FF52_22529	4.528e-175	573.0	COG1649@1|root,COG3291@1|root,COG4632@1|root,COG1649@2|Bacteria,COG3291@2|Bacteria,COG4632@2|Bacteria,4NK43@976|Bacteroidetes,1ICDG@117743|Flavobacteriia,2NY76@237|Flavobacterium	2|Bacteria	GV	PKD domain	tagL	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,DUF11,DUF4988,GHL10,NAGPA,SLH
CSH2_k127_2743751_1	1341155.FSS13T_18760	5.461e-52	186.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1I2X2@117743|Flavobacteriia,2NWT5@237|Flavobacterium	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
CSH2_k127_2743751_3	886377.Murru_2889	1.624e-26	109.0	COG4898@1|root,COG4898@2|Bacteria,4NQGY@976|Bacteroidetes,1I2X8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CSH2_k127_2745242_1	1453500.AT05_10770	1.507e-150	483.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1HWRM@117743|Flavobacteriia	976|Bacteroidetes	G	major facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
CSH2_k127_2745242_0	1267211.KI669560_gene1442	6.988e-194	615.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	amyA2	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
CSH2_k127_2754146_0	700598.Niako_6434	4.6e-109	359.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CSH2_k127_2754146_2	700598.Niako_6433	4.507e-33	134.0	2DRKN@1|root,33C6H@2|Bacteria,4NZAT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2754146_1	700598.Niako_6432	5.636e-36	136.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1ITUM@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CSH2_k127_2760972_0	929556.Solca_1072	6.496e-197	619.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1INPD@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
CSH2_k127_2760972_1	925409.KI911562_gene327	3.17e-115	381.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IPV2@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria (DUF2329)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3131,Glycoamylase
CSH2_k127_2772917_0	925409.KI911562_gene1080	1.202e-205	647.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CSH2_k127_2772917_1	1122605.KB893646_gene80	6.784e-72	249.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1ISUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
CSH2_k127_2778679_3	926562.Oweho_1087	7.25e-07	55.0	2DKFZ@1|root,309D6@2|Bacteria,4PK7J@976|Bacteroidetes,1IFCY@117743|Flavobacteriia,2PB0S@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
CSH2_k127_2778679_1	700598.Niako_2153	6.552e-98	332.0	COG4632@1|root,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes,1ITPU@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,fn3
CSH2_k127_2778679_0	1123248.KB893323_gene1621	2.886e-167	529.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CSH2_k127_2778679_2	485918.Cpin_1965	9.729e-09	57.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2778951_0	1189620.AJXL01000001_gene1769	1.604e-127	415.0	COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia,2NT81@237|Flavobacterium	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
CSH2_k127_2779953_0	1121875.KB907549_gene2024	1.5e-91	307.0	COG2303@1|root,COG2303@2|Bacteria,4NMEP@976|Bacteroidetes,1IA7R@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
CSH2_k127_2780104_2	1131812.JQMS01000001_gene927	5.82e-11	64.0	COG2308@1|root,COG2308@2|Bacteria,4NFMN@976|Bacteroidetes,1HXQ6@117743|Flavobacteriia,2NU8C@237|Flavobacterium	976|Bacteroidetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
CSH2_k127_2780104_0	1123248.KB893318_gene4229	5.321e-54	190.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CSH2_k127_2780460_1	1120951.AUBG01000002_gene1443	8.594e-37	141.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CSH2_k127_2780460_0	1123248.KB893337_gene2460	1.994e-145	467.0	COG4206@1|root,COG4206@2|Bacteria,4PKY5@976|Bacteroidetes,1IQUU@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CSH2_k127_2796836_1	929556.Solca_2696	8.889e-14	72.0	COG2755@1|root,COG2755@2|Bacteria,4NPB3@976|Bacteroidetes,1J195@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CSH2_k127_2796836_0	700598.Niako_5229	2.951e-169	536.0	2DB9J@1|root,2Z7X1@2|Bacteria,4NGUY@976|Bacteroidetes,1IQJ4@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109
CSH2_k127_2811113_0	1122605.KB893634_gene4205	3.3e-227	711.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CSH2_k127_2811113_1	700598.Niako_6519	3.862e-76	261.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1IV4X@117747|Sphingobacteriia	976|Bacteroidetes	K	CRP FNR family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CSH2_k127_2815007_2	313606.M23134_04518	8.558e-42	173.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes,47UFX@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14,TPR_16
CSH2_k127_2815007_1	468059.AUHA01000007_gene2657	4.442e-50	186.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1IS5X@117747|Sphingobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
CSH2_k127_2815007_0	700598.Niako_6026	2.194e-78	267.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1IW6H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CSH2_k127_2822664_0	1123248.KB893319_gene3994	2.729e-127	415.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,1INUU@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydroxypyruvate isomerase	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CSH2_k127_2822664_1	925409.KI911562_gene917	2.798e-39	148.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,1IQZG@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_2827360_1	1123248.KB893318_gene4149	2.649e-51	184.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1IPT2@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CSH2_k127_2827360_0	925409.KI911562_gene88	3.958e-142	463.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
CSH2_k127_2829699_0	925409.KI911562_gene289	1.158e-67	236.0	COG0491@1|root,COG0491@2|Bacteria,4NINV@976|Bacteroidetes,1IS2X@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CSH2_k127_2829699_1	517417.Cpar_0887	1.493e-07	54.0	COG0464@1|root,COG0464@2|Bacteria,1FFD6@1090|Chlorobi	1090|Chlorobi	O	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CSH2_k127_2831436_0	468059.AUHA01000005_gene2614	2.352e-22	100.0	COG2085@1|root,COG2085@2|Bacteria,4NPSZ@976|Bacteroidetes,1IYAV@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
CSH2_k127_2840813_1	700598.Niako_0289	1.738e-28	119.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1ITEJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CSH2_k127_2840813_0	925409.KI911562_gene63	3.88e-210	666.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_2850794_0	1123248.KB893386_gene1833	2.023e-167	531.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CSH2_k127_2850794_1	485918.Cpin_0879	2.828e-54	194.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1IRD0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CSH2_k127_2853790_0	1267211.KI669560_gene1815	4.618e-174	550.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1IP8R@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
CSH2_k127_2855258_1	1120965.AUBV01000010_gene2777	9.141e-16	79.0	2CJWE@1|root,30Y1E@2|Bacteria,4NNQQ@976|Bacteroidetes,47N1F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2855258_0	1034807.FBFL15_2227	2.619e-108	357.0	COG2207@1|root,COG2207@2|Bacteria,4NEHD@976|Bacteroidetes,1HZSB@117743|Flavobacteriia,2NTVX@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CSH2_k127_2857357_0	1123248.KB893314_gene3588	4.043e-149	475.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CSH2_k127_2859878_0	391587.KAOT1_17403	5.742e-102	339.0	COG5360@1|root,COG5360@2|Bacteria,4NH16@976|Bacteroidetes,1I0J6@117743|Flavobacteriia	976|Bacteroidetes	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
CSH2_k127_2859878_1	1506583.JQJY01000005_gene2327	1.989e-18	85.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,2NUTA@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CSH2_k127_2865557_0	452637.Oter_1671	1.442e-198	631.0	COG0591@1|root,COG0591@2|Bacteria,46S93@74201|Verrucomicrobia,3K7R7@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CSH2_k127_2866538_0	1122605.KB893625_gene2098	8.671e-95	316.0	28I6D@1|root,2Z89E@2|Bacteria,4NIIX@976|Bacteroidetes,1IPPJ@117747|Sphingobacteriia	976|Bacteroidetes	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
CSH2_k127_2866538_1	29306.JOBE01000022_gene513	2.138e-21	99.0	COG3506@1|root,COG3506@2|Bacteria,2GJ86@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
CSH2_k127_287212_0	1089547.KB913013_gene2324	1.36e-84	286.0	COG1858@1|root,COG1858@2|Bacteria,4NJGU@976|Bacteroidetes,47NXP@768503|Cytophagia	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CSH2_k127_2872335_0	700598.Niako_6077	1.164e-249	777.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1IV6E@117747|Sphingobacteriia	976|Bacteroidetes	CI	MaoC like domain	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
CSH2_k127_2872335_2	700598.Niako_4444	1.492e-08	64.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_2872335_1	1267211.KI669560_gene363	3.599e-85	287.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISB0@117747|Sphingobacteriia	976|Bacteroidetes	O	methionine sulfoxide reductase	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
CSH2_k127_2876815_0	700598.Niako_5048	1.704e-173	550.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IURB@117747|Sphingobacteriia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CSH2_k127_2879767_1	700598.Niako_6678	2.389e-53	196.0	COG1560@1|root,COG1560@2|Bacteria,4NPAI@976|Bacteroidetes,1J0BY@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CSH2_k127_2879767_0	925409.KI911562_gene414	2.199e-77	263.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CSH2_k127_2883201_1	925409.KI911562_gene1133	7.674e-08	53.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CSH2_k127_2883201_0	1239962.C943_02231	1.031e-129	419.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2889125_0	925409.KI911562_gene1379	3.951e-312	970.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IUT7@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_2889425_1	714943.Mucpa_0146	1.284e-08	63.0	COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,SprB
CSH2_k127_2889425_0	1122179.KB890491_gene4477	2.252e-19	95.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,Glug
CSH2_k127_2893384_0	929562.Emtol_3375	1.324e-304	940.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CSH2_k127_289368_1	1123248.KB893315_gene3077	6.918e-18	89.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQCN@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_289368_0	402777.KB235903_gene1756	4.413e-40	168.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
CSH2_k127_2905601_0	929562.Emtol_4149	2.197e-117	383.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,47KIP@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
CSH2_k127_2910889_1	1123248.KB893314_gene3618	6.018e-43	169.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	OMP_b-brl
CSH2_k127_2910889_0	925409.KI911562_gene312	7.456e-105	344.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1IPXY@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CSH2_k127_2911647_1	762903.Pedsa_1215	1.203e-16	82.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1ITV6@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_2911647_0	880070.Cycma_0657	6.712e-92	312.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CSH2_k127_2917938_1	1123248.KB893314_gene3626	6.976e-38	147.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1IP9Q@117747|Sphingobacteriia	976|Bacteroidetes	H	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CSH2_k127_2917938_0	485918.Cpin_3090	6.689e-117	379.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1IPD8@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CSH2_k127_2920023_1	485918.Cpin_2055	1.489e-29	130.0	COG5571@1|root,COG5571@2|Bacteria,4NMTM@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
CSH2_k127_2920023_0	1267211.KI669560_gene739	3.528e-55	198.0	COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes	976|Bacteroidetes	L	Phenylacetate-CoA oxygenase	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
CSH2_k127_2920400_2	1392490.JHZX01000001_gene781	9.324e-19	87.0	2AR54@1|root,31GER@2|Bacteria,4NSCR@976|Bacteroidetes,1I3DE@117743|Flavobacteriia	976|Bacteroidetes	J	30S ribosomal protein S23	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CSH2_k127_2920400_0	925409.KI911562_gene1624	9.219e-221	692.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPMC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CSH2_k127_2920400_1	867902.Ornrh_0091	4.241e-114	372.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CSH2_k127_2922596_1	1122605.KB893644_gene1351	9.638e-41	154.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1IQME@117747|Sphingobacteriia	976|Bacteroidetes	K	response regulator, receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CSH2_k127_2922596_0	926549.KI421517_gene2103	1.252e-92	312.0	COG2972@1|root,COG2972@2|Bacteria,4NHG3@976|Bacteroidetes,47NHD@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
CSH2_k127_2922657_0	925409.KI911562_gene2072	1.061e-103	341.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1IQMR@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
CSH2_k127_2922657_3	1121859.KB890738_gene3022	1.774e-50	194.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,47RWM@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
CSH2_k127_2922657_2	929713.NIASO_03880	9.88e-63	227.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1ITW4@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
CSH2_k127_2922657_4	700598.Niako_0428	1.076e-23	102.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CSH2_k127_2922657_1	700598.Niako_0428	3.25e-69	235.0	COG0717@1|root,COG0717@2|Bacteria,4NFRS@976|Bacteroidetes	976|Bacteroidetes	F	Deoxycytidine triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CSH2_k127_292500_0	1121904.ARBP01000018_gene2707	4.536e-176	560.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,47YNU@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CSH2_k127_292500_1	1121875.KB907556_gene612	9.304e-32	132.0	2E5SP@1|root,330H2@2|Bacteria,4P4B3@976|Bacteroidetes	976|Bacteroidetes	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
CSH2_k127_2955797_1	700598.Niako_5758	1.751e-20	92.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1ISX9@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CSH2_k127_2955797_0	1122605.KB893646_gene145	9.139e-28	119.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_9
CSH2_k127_2955797_2	925409.KI911562_gene887	4.762e-18	87.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1INNS@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CSH2_k127_295773_1	1166018.FAES_5053	6.887e-64	224.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CSH2_k127_295773_0	700598.Niako_2567	3.147e-82	284.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CSH2_k127_2970182_2	526227.Mesil_3477	0.0002378	45.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CSH2_k127_2970182_1	1267211.KI669560_gene747	1.858e-20	96.0	2DBS0@1|root,2ZANT@2|Bacteria,4NQP3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2970182_0	1122605.KB893637_gene3108	9.253e-238	738.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CSH2_k127_2980719_3	700598.Niako_6365	1.181e-32	136.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,1IPER@117747|Sphingobacteriia	976|Bacteroidetes	S	FUSC-like inner membrane protein yccS	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
CSH2_k127_2980719_2	1341181.FLJC2902T_22250	4.279e-100	332.0	COG3662@1|root,COG3662@2|Bacteria,4NEYP@976|Bacteroidetes,1HWJP@117743|Flavobacteriia,2NUUE@237|Flavobacterium	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
CSH2_k127_2980719_1	761193.Runsl_1134	3.835e-106	355.0	COG5434@1|root,COG5434@2|Bacteria,4NFZJ@976|Bacteroidetes,47K9P@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,fn3
CSH2_k127_2980719_0	761193.Runsl_2021	3.115e-157	505.0	COG5434@1|root,COG5434@2|Bacteria,4NE9Y@976|Bacteroidetes,47KM6@768503|Cytophagia	976|Bacteroidetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CSH2_k127_2980719_4	485918.Cpin_1881	4.083e-15	76.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1IUPB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
CSH2_k127_2980719_5	1463936.JOJI01000007_gene3666	2.292e-14	72.0	COG0330@1|root,COG0330@2|Bacteria,2GM0Z@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Band 7 protein	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
CSH2_k127_2991804_1	1050202.KB913024_gene2503	3.655e-13	72.0	2DNZR@1|root,32ZYK@2|Bacteria,2GQYS@201174|Actinobacteria,409C6@622450|Actinopolysporales	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
CSH2_k127_2991804_0	1124780.ANNU01000008_gene2729	7.728e-30	126.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,47KF2@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CSH2_k127_3000859_1	1336803.PHEL49_2655	9.391e-08	60.0	2EZ38@1|root,33S9G@2|Bacteria,4P0FQ@976|Bacteroidetes,1I8CU@117743|Flavobacteriia,3VWYX@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3000859_0	1123248.KB893319_gene4004	1.067e-29	119.0	2BZQY@1|root,2ZVH4@2|Bacteria,4P73I@976|Bacteroidetes,1IZGJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3005067_0	485918.Cpin_0825	1.683e-64	226.0	COG1136@1|root,COG1136@2|Bacteria,4NN5Z@976|Bacteroidetes,1IXVG@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_3012515_3	693979.Bache_2189	1.543e-06	59.0	COG2885@1|root,COG2885@2|Bacteria,4NKE3@976|Bacteroidetes,2FNTG@200643|Bacteroidia,4APE3@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
CSH2_k127_3012515_0	1121904.ARBP01000009_gene4366	2.552e-52	189.0	2CKSR@1|root,30RNP@2|Bacteria,4PB67@976|Bacteroidetes,47VAI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3012515_2	930169.B5T_01687	1.324e-15	87.0	COG3126@1|root,COG3650@1|root,COG3126@2|Bacteria,COG3650@2|Bacteria,1N8AF@1224|Proteobacteria,1SCM7@1236|Gammaproteobacteria,1XS8E@135619|Oceanospirillales	135619|Oceanospirillales	S	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	YscW
CSH2_k127_3012515_1	485918.Cpin_7085	3.204e-17	81.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CSH2_k127_3014749_0	1122605.KB893630_gene4061	2.071e-149	479.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CSH2_k127_3019471_0	926556.Echvi_3096	5.899e-09	65.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,47X8T@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CSH2_k127_3022734_1	925409.KI911562_gene1015	1.015e-182	579.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1J0U0@117747|Sphingobacteriia	976|Bacteroidetes	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
CSH2_k127_3022734_0	1267211.KI669560_gene130	7.971e-237	745.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1IPWZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
CSH2_k127_3032232_0	700598.Niako_0108	3.216e-213	664.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1IP8F@117747|Sphingobacteriia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CSH2_k127_303565_0	861299.J421_4478	1.433e-155	500.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CSH2_k127_3038577_1	1239962.C943_01413	1.643e-16	81.0	2ANDI@1|root,31DC5@2|Bacteria,4NSSW@976|Bacteroidetes,47PXY@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
CSH2_k127_3038577_0	1123248.KB893348_gene241	5.387e-194	608.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1INSY@117747|Sphingobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CSH2_k127_3054072_0	1267211.KI669560_gene520	9e-213	666.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CSH2_k127_305759_2	938709.AUSH02000031_gene1304	8.275e-25	103.0	COG5285@1|root,COG5285@2|Bacteria,4NGMY@976|Bacteroidetes	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CSH2_k127_305759_0	938709.AUSH02000031_gene1305	9.613e-91	306.0	COG1082@1|root,COG1082@2|Bacteria,4NFEA@976|Bacteroidetes	976|Bacteroidetes	G	Pfam Xylose	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_305759_1	1166018.FAES_5278	7.665e-39	148.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,47NSK@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
CSH2_k127_3058856_0	1123248.KB893386_gene1983	2.28e-136	441.0	COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,1IV8M@117747|Sphingobacteriia	976|Bacteroidetes	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CSH2_k127_3059182_2	1121287.AUMU01000003_gene2909	5.956e-36	141.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia,3ZP9M@59732|Chryseobacterium	976|Bacteroidetes	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CSH2_k127_3059182_0	700598.Niako_0551	2.249e-148	475.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1IPUJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CSH2_k127_3059182_1	700598.Niako_0550	1.959e-48	180.0	COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes,1ISZY@117747|Sphingobacteriia	976|Bacteroidetes	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CSH2_k127_3059683_3	700598.Niako_4518	3.288e-69	239.0	COG1595@1|root,COG1595@2|Bacteria,4NP02@976|Bacteroidetes,1J06I@117747|Sphingobacteriia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_3059683_4	700598.Niako_4519	3.75e-27	117.0	2EDN0@1|root,337HT@2|Bacteria,4NVQJ@976|Bacteroidetes,1ITXS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3059683_2	992406.RIA_1900	2.147e-82	283.0	28HDX@1|root,2Z7QG@2|Bacteria,4NFID@976|Bacteroidetes,1HZD2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3059683_1	1122605.KB893626_gene2383	1.106e-98	329.0	COG3000@1|root,COG3000@2|Bacteria,4NI62@976|Bacteroidetes	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_3059683_0	700598.Niako_6359	7.782e-159	503.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CSH2_k127_3061880_0	1123248.KB893325_gene1159	1.168e-112	376.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CSH2_k127_3061880_1	1123248.KB893321_gene471	8.633e-24	101.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CSH2_k127_306402_0	700598.Niako_1202	6.24e-89	304.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CSH2_k127_307295_0	1267211.KI669560_gene525	4.803e-131	426.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CSH2_k127_308167_0	925409.KI911562_gene2716	8.693e-181	569.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1IP50@117747|Sphingobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CSH2_k127_3082819_1	929713.NIASO_05455	3.336e-30	123.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IPQ2@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CSH2_k127_3082819_0	1267211.KI669560_gene1616	1.821e-117	384.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CSH2_k127_3087255_0	1223410.KN050846_gene1076	1.122e-59	214.0	COG0457@1|root,COG0457@2|Bacteria,4NJ7M@976|Bacteroidetes,1I0QV@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_6,TPR_8
CSH2_k127_3087255_1	700598.Niako_5782	1.923e-09	65.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1IQH4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
CSH2_k127_3087381_0	1121887.AUDK01000022_gene2853	1.306e-60	220.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IG7Z@117743|Flavobacteriia,2NXGA@237|Flavobacterium	976|Bacteroidetes	M	Male sterility protein	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CSH2_k127_3087381_1	762903.Pedsa_3694	1.864e-18	92.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,1ITBG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_3095424_0	929703.KE386491_gene3023	2.532e-45	173.0	COG1030@1|root,COG1030@2|Bacteria,4PN0T@976|Bacteroidetes,47YFF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
CSH2_k127_3095424_1	700598.Niako_6315	1.044e-27	113.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,1IVSR@117747|Sphingobacteriia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CSH2_k127_3095437_0	649349.Lbys_0274	2.207e-63	222.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47UBJ@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III-like domain	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_3095437_1	398720.MED217_09095	1.082e-40	157.0	COG0664@1|root,COG0664@2|Bacteria,4NSMK@976|Bacteroidetes,1IIWC@117743|Flavobacteriia,2XK96@283735|Leeuwenhoekiella	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CSH2_k127_3095437_2	926559.JoomaDRAFT_1442	1.084e-18	88.0	COG2318@1|root,COG2318@2|Bacteria,4NRSP@976|Bacteroidetes,1I34C@117743|Flavobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CSH2_k127_3095974_0	1123248.KB893331_gene3758	5.56e-159	507.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,1J0QZ@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CSH2_k127_3099849_0	761193.Runsl_5260	6.426e-75	255.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CSH2_k127_3099849_2	504487.JCM19302_3076	4.672e-29	124.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1I1ZF@117743|Flavobacteriia	976|Bacteroidetes	H	synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CSH2_k127_3099849_1	929713.NIASO_19245	7.011e-30	123.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1ISCG@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydrobiopterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CSH2_k127_3103016_0	700598.Niako_6625	5.399e-98	325.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CSH2_k127_3103016_1	929713.NIASO_17990	1.581e-37	146.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CSH2_k127_3113107_0	1123248.KB893318_gene4199	3.929e-98	332.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1IP68@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
CSH2_k127_3113107_1	1122605.KB893625_gene2005	8.276e-46	167.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1IRVT@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CSH2_k127_3115331_1	1118057.CAGX01000042_gene560	1.016e-10	72.0	COG0484@1|root,COG0484@2|Bacteria,1V5G5@1239|Firmicutes,24JFC@186801|Clostridia,22GQJ@1570339|Peptoniphilaceae	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3115331_0	1122605.KB893644_gene1371	7.042e-147	467.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1INX4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CSH2_k127_3121277_1	700598.Niako_1262	4.171e-112	367.0	COG1969@1|root,COG1969@2|Bacteria,4NIDY@976|Bacteroidetes,1IP16@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1969 Ni Fe-hydrogenase I cytochrome b subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
CSH2_k127_3121277_0	714943.Mucpa_5245	2.109e-237	738.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1IPFW@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0374 Ni Fe-hydrogenase I large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
CSH2_k127_3127118_0	1123248.KB893345_gene31	5.548e-243	757.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,1IQSQ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
CSH2_k127_313705_0	1267211.KI669560_gene2785	5.22e-125	403.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
CSH2_k127_3137614_2	1123248.KB893314_gene3648	4.786e-30	119.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CSH2_k127_3137614_1	1454007.JAUG01000002_gene2973	7.646e-37	142.0	COG2076@1|root,COG2076@2|Bacteria,4NQ4U@976|Bacteroidetes	976|Bacteroidetes	P	Multidrug resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
CSH2_k127_3137614_0	925409.KI911562_gene2438	2.489e-295	912.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IWY5@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
CSH2_k127_3137614_3	1229276.DI53_1035	1.147e-22	101.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
CSH2_k127_3150140_2	929713.NIASO_13590	3.15e-14	72.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,1INVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CSH2_k127_3150140_1	700598.Niako_6303	2.015e-47	173.0	COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,1ITGU@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CSH2_k127_3150140_0	925409.KI911562_gene619	5.009e-75	258.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1IY4A@117747|Sphingobacteriia	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CSH2_k127_315050_0	925409.KI911562_gene1201	1.761e-224	698.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CSH2_k127_3150838_0	1267211.KI669560_gene1988	4.06e-232	721.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_3150838_1	643867.Ftrac_0192	5.456e-20	101.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
CSH2_k127_3154528_0	925409.KI911562_gene1484	2.813e-95	323.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_3154528_1	1267211.KI669560_gene2676	3.872e-56	207.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_3169867_1	925409.KI911562_gene434	2.504e-51	184.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IPNP@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ComB family	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
CSH2_k127_3169867_0	925409.KI911562_gene782	3.959e-104	345.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,1IRWP@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
CSH2_k127_3169975_0	1237149.C900_05889	4.285e-125	410.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,47KB6@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CSH2_k127_3173404_0	313595.P700755_001243	3.966e-67	243.0	COG4249@1|root,COG4249@2|Bacteria,4NIFD@976|Bacteroidetes,1IAT1@117743|Flavobacteriia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CSH2_k127_3179940_0	1233950.IW22_10730	1.309e-107	367.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1HXCP@117743|Flavobacteriia,3ZP88@59732|Chryseobacterium	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CSH2_k127_3179940_1	1123248.KB893340_gene2662	1.282e-77	271.0	COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,1IQ1K@117747|Sphingobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CSH2_k127_3180279_0	700598.Niako_5241	1.626e-109	361.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IQ0I@117747|Sphingobacteriia	976|Bacteroidetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
CSH2_k127_3183936_1	925409.KI911562_gene2824	1.298e-103	339.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,1INR8@117747|Sphingobacteriia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CSH2_k127_3183936_2	925409.KI911562_gene2825	7.436e-24	101.0	COG0690@1|root,COG0690@2|Bacteria,4PGJJ@976|Bacteroidetes,1ITUV@117747|Sphingobacteriia	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CSH2_k127_3183936_0	1123248.KB893381_gene1066	2.007e-173	545.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1IPDP@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CSH2_k127_318519_1	1249997.JHZW01000003_gene3845	6.337e-32	128.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I4A2@117743|Flavobacteriia,2PISF@252356|Maribacter	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CSH2_k127_318519_0	1123248.KB893348_gene312	1.685e-92	308.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CSH2_k127_3186479_1	485918.Cpin_0240	6.795e-31	128.0	2DICZ@1|root,32UAY@2|Bacteria,4NU7D@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3186479_0	700598.Niako_5634	3.45e-82	279.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1IRI4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CSH2_k127_3186479_2	649349.Lbys_2296	1.757e-09	61.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia	976|Bacteroidetes	N	ABC transporter substrate-binding component GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CSH2_k127_3192045_2	485918.Cpin_6226	8.925e-25	108.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA,Plug,TonB_dep_Rec
CSH2_k127_3192045_0	700598.Niako_1171	4.869e-102	336.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1IPI8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
CSH2_k127_3192045_1	700598.Niako_1170	5.461e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1ITRK@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CSH2_k127_319620_1	1267211.KI669560_gene1718	2.324e-32	128.0	29UQ5@1|root,30G1W@2|Bacteria,4NKX5@976|Bacteroidetes,1IS42@117747|Sphingobacteriia	976|Bacteroidetes	Q	spheroidene monooxygenase	crtA	-	-	-	-	-	-	-	-	-	-	-	DUF3291
CSH2_k127_319620_0	700598.Niako_0984	1.926e-129	419.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,1IP21@117747|Sphingobacteriia	976|Bacteroidetes	E	Arginine deiminase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
CSH2_k127_3206317_0	1267211.KI669560_gene998	1.609e-146	476.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1IV3Y@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
CSH2_k127_3208540_0	929556.Solca_2104	1.034e-162	517.0	28JHC@1|root,2Z9AX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
CSH2_k127_3210635_2	1122605.KB893637_gene3078	1.237e-16	81.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1IR77@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CSH2_k127_3210635_0	700598.Niako_5463	7.562e-78	267.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CSH2_k127_3210635_1	1123248.KB893316_gene4658	7.366e-25	105.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_3260962_1	421531.IX38_09975	0.0003295	51.0	28MB1@1|root,2ZAPK@2|Bacteria,4NHMB@976|Bacteroidetes,1I377@117743|Flavobacteriia,3ZQMJ@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3260962_0	1122605.KB893637_gene3056	5.041e-119	387.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CSH2_k127_3262855_0	925409.KI911562_gene2360	2.76e-123	400.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,1IQ2K@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CSH2_k127_3262855_3	1123248.KB893314_gene3652	1.977e-30	128.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1IU5B@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CSH2_k127_3262855_4	1137281.D778_01433	4.876e-26	117.0	COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,1I1IJ@117743|Flavobacteriia	976|Bacteroidetes	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
CSH2_k127_3262855_1	700598.Niako_1004	8.523e-69	242.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS97@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CSH2_k127_3262855_2	925409.KI911562_gene2490	3.281e-49	183.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IQZY@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CSH2_k127_3265280_0	925409.KI911562_gene299	1.332e-140	453.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CSH2_k127_3272285_1	700598.Niako_0947	2.04e-49	181.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,1ISW1@117747|Sphingobacteriia	976|Bacteroidetes	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
CSH2_k127_3272285_0	925409.KI911562_gene1822	1.077e-99	329.0	COG1428@1|root,COG1428@2|Bacteria,4PM5R@976|Bacteroidetes,1IXF2@117747|Sphingobacteriia	976|Bacteroidetes	F	Thymidylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
CSH2_k127_3287049_1	1267211.KI669560_gene344	4.098e-25	109.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
CSH2_k127_3287049_0	925409.KI911562_gene745	8.968e-80	275.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1IXDH@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_3289628_0	1123248.KB893337_gene2406	1.182e-260	810.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CSH2_k127_3295067_0	925409.KI911562_gene479	4.48e-204	646.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CSH2_k127_3295067_1	925409.KI911562_gene1046	1.186e-07	53.0	COG0860@1|root,COG0860@2|Bacteria,4NH6Q@976|Bacteroidetes	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
CSH2_k127_3298622_0	925409.KI911562_gene1789	2.91e-178	565.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CSH2_k127_3302934_1	1123058.KB894229_gene1133	1.709e-10	68.0	COG0628@1|root,COG0628@2|Bacteria,4NIB3@976|Bacteroidetes,1HYV6@117743|Flavobacteriia	976|Bacteroidetes	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CSH2_k127_3302934_0	1434325.AZQN01000008_gene2924	1.982e-60	214.0	COG0662@1|root,COG0662@2|Bacteria,4NNWT@976|Bacteroidetes,47Q0Y@768503|Cytophagia	976|Bacteroidetes	G	PFAM Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
CSH2_k127_3303384_0	643867.Ftrac_3795	2.293e-59	217.0	COG1216@1|root,COG1216@2|Bacteria,4NKAZ@976|Bacteroidetes,47SJI@768503|Cytophagia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_3304979_0	929556.Solca_2192	3.164e-168	559.0	COG4913@1|root,COG4913@2|Bacteria,4NFA3@976|Bacteroidetes,1IX2E@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SbcCD_C
CSH2_k127_3309097_0	1123248.KB893386_gene1831	1.165e-67	237.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1ISIT@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CSH2_k127_3309097_1	700598.Niako_5798	5.18e-38	147.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
CSH2_k127_3314746_0	1123248.KB893315_gene3210	0.0	1097.0	COG3408@1|root,COG3408@2|Bacteria,4PKJG@976|Bacteroidetes,1IQX7@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
CSH2_k127_3329003_2	439235.Dalk_2772	5.095e-17	81.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,2MJS3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
CSH2_k127_3329003_0	382464.ABSI01000011_gene3046	1.429e-37	148.0	COG1409@1|root,COG1409@2|Bacteria,46XGN@74201|Verrucomicrobia,2IVV6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CSH2_k127_3329003_1	1267211.KI669560_gene2452	2.065e-29	120.0	COG0526@1|root,COG0607@1|root,COG0526@2|Bacteria,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1IUCC@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CSH2_k127_3337413_1	700598.Niako_0357	2.194e-52	186.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1IQIF@117747|Sphingobacteriia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CSH2_k127_3337413_0	1123248.KB893316_gene4542	5.63e-166	528.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1IQIH@117747|Sphingobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CSH2_k127_3340066_0	700598.Niako_6019	5.913e-87	289.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1J0KU@117747|Sphingobacteriia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
CSH2_k127_3340066_1	1305737.JAFX01000001_gene1585	3.467e-22	103.0	COG3637@1|root,COG3637@2|Bacteria,4NUVV@976|Bacteroidetes,47WY7@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3357670_0	929713.NIASO_18295	1.214e-99	333.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes,1IQQH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CSH2_k127_3367805_0	700598.Niako_1542	1.933e-82	286.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1IPAV@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_3376512_1	1267211.KI669560_gene2690	1.946e-30	120.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1IVZZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CSH2_k127_3376512_0	700598.Niako_7344	3.065e-63	227.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes	976|Bacteroidetes	S	Hydrolase with alpha beta fold protein	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CSH2_k127_3385261_0	929562.Emtol_4148	9.714e-182	575.0	COG4447@1|root,COG4447@2|Bacteria,4NK01@976|Bacteroidetes,47NT3@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_3385261_1	1267211.KI669560_gene525	1.819e-42	159.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CSH2_k127_3386685_2	925409.KI911562_gene1020	2.833e-67	231.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1IPBN@117747|Sphingobacteriia	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3386685_0	485918.Cpin_0523	1.137e-145	469.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1IPEE@117747|Sphingobacteriia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CSH2_k127_3386685_1	700598.Niako_6475	3.099e-76	258.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1IPZE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CSH2_k127_3394748_0	485918.Cpin_7094	5.526e-85	287.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1IQ48@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CSH2_k127_339884_0	1267211.KI669560_gene1020	4.916e-128	417.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IWT6@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_3404232_1	1123248.KB893330_gene416	2.369e-14	74.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CSH2_k127_3404232_0	1123248.KB893320_gene3844	1.93e-170	557.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1IQ3X@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
CSH2_k127_3405845_1	1123248.KB893321_gene522	9.652e-35	139.0	COG4270@1|root,COG4270@2|Bacteria,4NVXH@976|Bacteroidetes,1IZMV@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CSH2_k127_3405845_0	398720.MED217_13109	4.868e-48	178.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NIFD@976|Bacteroidetes,1I1QH@117743|Flavobacteriia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CSH2_k127_3410786_0	925409.KI911562_gene1560	3.532e-133	435.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CSH2_k127_3410786_1	1267211.KI669560_gene2472	9.561e-102	336.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CSH2_k127_3417634_1	700598.Niako_2487	4.596e-46	171.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
CSH2_k127_3417634_0	616991.JPOO01000001_gene3960	1.472e-124	407.0	COG0385@1|root,COG0385@2|Bacteria,4NEDA@976|Bacteroidetes,1HXX2@117743|Flavobacteriia,23G18@178469|Arenibacter	976|Bacteroidetes	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
CSH2_k127_3418707_4	485918.Cpin_3113	4.528e-32	132.0	COG1208@1|root,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,1ITPM@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
CSH2_k127_3418707_3	925409.KI911562_gene2207	2.84e-71	246.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IRJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CSH2_k127_3418707_2	1123248.KB893317_gene4285	1.641e-139	450.0	COG2605@1|root,COG2605@2|Bacteria,4NHEN@976|Bacteroidetes,1IU21@117747|Sphingobacteriia	976|Bacteroidetes	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
CSH2_k127_3418707_1	700598.Niako_2546	6.184e-143	462.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_3418707_0	1267211.KI669560_gene1743	2.155e-148	474.0	COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,1J0R0@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_3421666_1	700598.Niako_5810	2.406e-34	136.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,1IRUG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CSH2_k127_3421666_0	1267211.KI669560_gene292	1.474e-55	201.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CSH2_k127_3421666_2	929713.NIASO_18820	1.607e-06	55.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CSH2_k127_3432125_1	90814.KL370891_gene30	1.607e-51	187.0	COG0406@1|root,COG0406@2|Bacteria,1N8GN@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CSH2_k127_3432125_0	925409.KI911562_gene616	6.325e-80	270.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1IVKB@117747|Sphingobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CSH2_k127_3444629_0	485918.Cpin_7295	4.084e-139	448.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1IRN3@117747|Sphingobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CSH2_k127_3444629_1	1223410.KN050846_gene2471	0.0005231	44.0	2E61B@1|root,32DNU@2|Bacteria,4NQ9X@976|Bacteroidetes,1I39V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3451259_1	1034807.FBFL15_1579	5.813e-176	559.0	COG0438@1|root,COG0438@2|Bacteria,4NGU7@976|Bacteroidetes,1I01U@117743|Flavobacteriia,2NV5G@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_3451259_0	483216.BACEGG_02125	1.247e-193	617.0	COG5360@1|root,COG5360@2|Bacteria,4NH16@976|Bacteroidetes,2FRE8@200643|Bacteroidia,4APXY@815|Bacteroidaceae	976|Bacteroidetes	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
CSH2_k127_3453077_0	925409.KI911562_gene1461	5.569e-127	412.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
CSH2_k127_3453077_1	700598.Niako_6492	2.198e-111	372.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CSH2_k127_3470981_2	504472.Slin_2330	4.236e-28	115.0	2E3VP@1|root,32YSV@2|Bacteria,4NV28@976|Bacteroidetes,47S3V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3470981_0	700598.Niako_6872	9.036e-210	653.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1IPMZ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CSH2_k127_3470981_1	925409.KI911562_gene359	1.456e-59	214.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,1IPE1@117747|Sphingobacteriia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CSH2_k127_3472320_0	1123248.KB893318_gene4168	9.945e-90	312.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_3489439_1	1123248.KB893324_gene1755	2.464e-31	123.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CSH2_k127_3489439_0	1123248.KB893324_gene1756	1.765e-130	422.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1IQ3E@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CSH2_k127_3489724_1	1042376.AFPK01000014_gene250	9.016e-05	44.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,1I173@117743|Flavobacteriia,406B0@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CSH2_k127_3489724_0	714943.Mucpa_2158	2.527e-92	317.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IR03@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CSH2_k127_3494258_2	1123248.KB893348_gene314	2.256e-08	58.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,1IT8X@117747|Sphingobacteriia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
CSH2_k127_3494258_0	1123248.KB893348_gene315	4.562e-187	597.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CSH2_k127_3494258_1	700598.Niako_6788	1.728e-66	231.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1ISDP@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
CSH2_k127_350207_0	1267211.KI669560_gene1862	3.329e-136	437.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,1IQC9@117747|Sphingobacteriia	976|Bacteroidetes	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CSH2_k127_350207_2	698769.JFBD01000042_gene814	4.913e-05	47.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_350207_1	866536.Belba_0068	3.003e-134	431.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,47NUB@768503|Cytophagia	976|Bacteroidetes	P	PFAM ZIP Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
CSH2_k127_3502422_0	700598.Niako_2016	9.04e-102	337.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CSH2_k127_3502422_1	1123248.KB893337_gene2513	1.107e-45	174.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IQ1U@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
CSH2_k127_3512950_0	700598.Niako_0455	4.082e-200	625.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1IP6V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140,ko:K22187	ko00040,ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00040,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935,R11768	RC00004,RC00080,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CSH2_k127_3512950_1	1123278.KB893488_gene6140	6.188e-47	170.0	COG0161@1|root,COG0161@2|Bacteria,4PMIJ@976|Bacteroidetes,47Q50@768503|Cytophagia	976|Bacteroidetes	H	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
CSH2_k127_3518733_0	243365.CV_2218	1.861e-120	396.0	COG2303@1|root,COG4757@1|root,COG2303@2|Bacteria,COG4757@2|Bacteria,1QQ8F@1224|Proteobacteria,2VH9Z@28216|Betaproteobacteria,2KU00@206351|Neisseriales	206351|Neisseriales	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CSH2_k127_3520709_1	925409.KI911562_gene2042	2.464e-118	387.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1IPJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CSH2_k127_3520709_2	1123248.KB893329_gene4470	1.337e-34	137.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CSH2_k127_3520709_0	925409.KI911562_gene2056	6.987e-170	538.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CSH2_k127_3530698_1	744872.Spica_0833	9.152e-56	199.0	COG0545@1|root,COG0545@2|Bacteria,2J77J@203691|Spirochaetes	203691|Spirochaetes	M	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CSH2_k127_3530698_0	700598.Niako_2089	3.673e-65	228.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1ISRY@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CSH2_k127_3530698_2	1168034.FH5T_05550	7.717e-11	63.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FWBD@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
CSH2_k127_3532946_3	1267211.KI669560_gene1566	2.726e-19	87.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IPEF@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CSH2_k127_3532946_2	1267211.KI669560_gene1991	2.408e-65	229.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,1ISBC@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CSH2_k127_3532946_0	925409.KI911562_gene2033	1.284e-198	626.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1IQ2Y@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CSH2_k127_3532946_1	700598.Niako_1031	2.114e-86	291.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1IS23@117747|Sphingobacteriia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CSH2_k127_3533014_1	760192.Halhy_3361	1.206e-41	157.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,1IRRN@117747|Sphingobacteriia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CSH2_k127_3533014_0	1123248.KB893315_gene3155	2.106e-160	520.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1ISDW@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
CSH2_k127_3538225_0	925409.KI911562_gene776	2.15e-175	557.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CSH2_k127_3540027_0	925409.KI911562_gene1180	8.805e-222	698.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CSH2_k127_3540027_1	700598.Niako_5589	3.568e-66	234.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1INQF@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CSH2_k127_3552854_0	925409.KI911562_gene1367	9.817e-215	670.0	COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1IP02@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
CSH2_k127_3552854_1	1089547.KB913013_gene4602	3.675e-108	356.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,47K0T@768503|Cytophagia	976|Bacteroidetes	S	alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CSH2_k127_3557290_0	1122605.KB893648_gene3661	3.472e-164	519.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
CSH2_k127_3559328_0	1123248.KB893348_gene333	1.182e-130	426.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQD7@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_3561202_0	1463855.JOHV01000007_gene5184	2.753e-73	252.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria	201174|Actinobacteria	M	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	DUF1080,ThuA
CSH2_k127_3561202_1	926549.KI421517_gene290	5.242e-50	181.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,47MC3@768503|Cytophagia	976|Bacteroidetes	G	fructose-bisphosphate aldolase, class II, yeast E. coli subtype	fbaA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CSH2_k127_3561371_1	1123248.KB893326_gene1309	3.85e-64	229.0	298K1@1|root,3122S@2|Bacteria,4PGXN@976|Bacteroidetes,1IUN3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3561371_0	1267211.KI669560_gene2384	6.796e-116	375.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CSH2_k127_3571905_0	1267211.KI669560_gene2060	7.299e-111	364.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IV0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
CSH2_k127_3571905_1	700598.Niako_1166	8.961e-67	233.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CSH2_k127_3571905_2	525373.HMPREF0766_10348	3.555e-58	212.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
CSH2_k127_3580426_1	153721.MYP_2121	4.683e-21	93.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3580426_0	925409.KI911562_gene1178	4.215e-92	309.0	COG2989@1|root,COG2989@2|Bacteria,4NKTZ@976|Bacteroidetes,1IRHA@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
CSH2_k127_3584662_2	1229276.DI53_2744	4.76e-38	149.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1ITSI@117747|Sphingobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
CSH2_k127_3584662_0	925409.KI911562_gene2482	7.059e-83	287.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,1IQV7@117747|Sphingobacteriia	976|Bacteroidetes	E	ABC transporter	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CSH2_k127_3584662_1	1296416.JACB01000017_gene5141	6.532e-62	222.0	COG0500@1|root,COG2226@2|Bacteria,4PH0U@976|Bacteroidetes,1IHRF@117743|Flavobacteriia,2YIT4@290174|Aquimarina	976|Bacteroidetes	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CSH2_k127_3584662_3	485918.Cpin_2016	8.45e-26	106.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CSH2_k127_3585067_1	1239962.C943_03759	9.686e-31	121.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CSH2_k127_3585067_0	485917.Phep_0833	9.277e-103	346.0	COG1305@1|root,COG1305@2|Bacteria,4NI22@976|Bacteroidetes,1INVZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3589263_0	398720.MED217_12314	6.979e-205	644.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia,2XI0X@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_3596454_0	1123248.KB893348_gene361	6.263e-136	441.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
CSH2_k127_3598842_3	1506583.JQJY01000001_gene497	4.324e-48	179.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes,1IAW1@117743|Flavobacteriia,2NWKD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3598842_2	700598.Niako_6467	1.02e-72	255.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CSH2_k127_3598842_0	700598.Niako_6465	3.143e-152	492.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1ISPB@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CSH2_k127_3598842_4	700598.Niako_1283	2.414e-07	61.0	2E82X@1|root,34BW2@2|Bacteria,4P6AY@976|Bacteroidetes,1IZ0Y@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3598842_1	1267211.KI669560_gene2044	4.266e-86	295.0	COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,1IS7G@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 domain	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
CSH2_k127_3601502_1	1189612.A33Q_1181	9.923e-09	59.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
CSH2_k127_3601502_0	1279009.ADICEAN_01401	3.94e-54	198.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CSH2_k127_3603012_1	468059.AUHA01000002_gene49	2.694e-51	188.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1IT61@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CSH2_k127_3603012_0	929562.Emtol_0805	8.581e-122	398.0	COG0513@1|root,COG0513@2|Bacteria,4NHCA@976|Bacteroidetes,47MGW@768503|Cytophagia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CSH2_k127_3603247_0	929562.Emtol_1162	8.194e-141	456.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CSH2_k127_3603742_1	1189620.AJXL01000130_gene1663	1.374e-27	115.0	COG0824@1|root,COG0824@2|Bacteria,4NR2W@976|Bacteroidetes,1I43T@117743|Flavobacteriia,2NUI9@237|Flavobacterium	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CSH2_k127_3603742_0	925409.KI911562_gene2937	2.379e-215	674.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CSH2_k127_3608230_0	1484157.PSNIH2_13370	4.942e-08	60.0	29B91@1|root,2ZY7D@2|Bacteria,1RGQ7@1224|Proteobacteria,1S4AT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Packaged DNA stabilization protein gp4	-	-	-	-	-	-	-	-	-	-	-	-	P22_Tail-4
CSH2_k127_3608230_1	640510.BC1001_5397	0.0003365	45.0	2AGR6@1|root,316YY@2|Bacteria,1PY6W@1224|Proteobacteria,2WDFP@28216|Betaproteobacteria,1KA7P@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3610550_3	1450525.JATV01000012_gene3055	7.917e-10	63.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,1HXPQ@117743|Flavobacteriia,2NSNB@237|Flavobacterium	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
CSH2_k127_3610550_1	1122605.KB893625_gene1992	1.437e-95	317.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1INNH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CSH2_k127_3610550_0	1123248.KB893370_gene4965	2.349e-142	456.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1IP51@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CSH2_k127_3615914_0	485918.Cpin_0500	2.343e-72	247.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1IQ9R@117747|Sphingobacteriia	976|Bacteroidetes	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CSH2_k127_3616508_0	313603.FB2170_05360	2.108e-182	580.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PGZ8@252356|Maribacter	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_3618867_1	517418.Ctha_1150	3.073e-95	320.0	COG0378@1|root,COG0378@2|Bacteria,1FDPQ@1090|Chlorobi	1090|Chlorobi	KO	TIGRFAM hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
CSH2_k127_3618867_0	929562.Emtol_2822	1.337e-211	683.0	COG0068@1|root,COG0068@2|Bacteria,4NIZ1@976|Bacteroidetes,47TB5@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM NiFe hydrogenase maturation protein HypF	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
CSH2_k127_3618867_3	700598.Niako_1269	1.169e-33	131.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes,1IUA2@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Hydrogenase expression formation protein, HupF HypC	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
CSH2_k127_3618867_2	1250232.JQNJ01000001_gene1811	1.309e-84	282.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes,1I089@117743|Flavobacteriia	976|Bacteroidetes	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
CSH2_k127_3621231_1	1321779.HMPREF1984_01811	7.671e-31	126.0	COG1894@1|root,COG1894@2|Bacteria,378S3@32066|Fusobacteria	32066|Fusobacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hymB	-	1.12.1.3	ko:K18331	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CSH2_k127_3621231_0	240292.Ava_4653	5.285e-47	174.0	COG1905@1|root,COG1905@2|Bacteria,1G54V@1117|Cyanobacteria,1HRBV@1161|Nostocales	1117|Cyanobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
CSH2_k127_3621231_2	938709.AUSH02000073_gene1679	1.653e-15	77.0	COG1914@1|root,COG1914@2|Bacteria,4NDZ1@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CSH2_k127_3624958_0	1123248.KB893322_gene581	5.879e-42	157.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CSH2_k127_3624958_1	700598.Niako_5595	4.142e-21	96.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1ITBU@117747|Sphingobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CSH2_k127_3627926_0	1123277.KB893172_gene538	2.9e-215	680.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CSH2_k127_3628559_0	886377.Murru_3297	2.84e-160	509.0	COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes,1I13H@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3628559_2	1237149.C900_05565	2.106e-99	331.0	COG3279@1|root,COG3279@2|Bacteria,4NP0E@976|Bacteroidetes,47Q29@768503|Cytophagia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
CSH2_k127_3628559_3	1239962.C943_04585	1.145e-60	216.0	2D9XB@1|root,32TU6@2|Bacteria,4NSXG@976|Bacteroidetes,47R3J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3628559_1	1237149.C900_05563	2.436e-103	344.0	COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes,47M8G@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CSH2_k127_3628956_0	1123248.KB893332_gene2278	1.484e-141	461.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,1J0M5@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_3633342_1	700598.Niako_4951	5.103e-37	156.0	COG0457@1|root,COG0457@2|Bacteria	700598.Niako_4951|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3633342_0	1123248.KB893386_gene1876	4.496e-58	206.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IP3S@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CSH2_k127_3650278_1	925409.KI911562_gene2109	1.834e-46	170.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CSH2_k127_3650278_0	1173024.KI912151_gene1625	5.413e-198	630.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
CSH2_k127_3650983_2	925409.KI911562_gene1031	1.16e-09	61.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1ISBF@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CSH2_k127_3650983_1	700598.Niako_6485	1.638e-21	95.0	2E5CT@1|root,3304V@2|Bacteria,4NUT8@976|Bacteroidetes,1IUKX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3650983_0	700598.Niako_0547	1.484e-194	614.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IR1H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CSH2_k127_3651348_0	925409.KI911562_gene1674	1.916e-77	264.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1IQV2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
CSH2_k127_3651348_1	485918.Cpin_2324	4.067e-35	141.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose reductase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CSH2_k127_3659062_0	925409.KI911562_gene1082	9.57e-77	273.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1IQ6P@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
CSH2_k127_3659062_1	762903.Pedsa_3159	8.398e-39	153.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1INQB@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_3660455_0	925409.KI911562_gene2645	1.747e-98	329.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CSH2_k127_3660455_1	700598.Niako_1602	4.79e-56	201.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1ITF8@117747|Sphingobacteriia	976|Bacteroidetes	F	cytidine and deoxycytidylate deaminase	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CSH2_k127_3660455_2	1270196.JCKI01000007_gene2478	1.119e-13	76.0	COG1943@1|root,COG1943@2|Bacteria,4NPU8@976|Bacteroidetes	976|Bacteroidetes	L	Pfam Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CSH2_k127_3660864_0	925409.KI911562_gene1054	5.289e-158	514.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,1IWMA@117747|Sphingobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CSH2_k127_3661939_0	925409.KI911562_gene1612	5.553e-108	353.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1IQ8J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CSH2_k127_3661939_1	925409.KI911562_gene1613	3.024e-63	222.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1IS44@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CSH2_k127_3661939_2	700598.Niako_5511	9.594e-46	171.0	2EB10@1|root,3351W@2|Bacteria,4NV9Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3661939_3	925409.KI911562_gene1623	3.01e-10	69.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3675266_0	316274.Haur_1525	2.566e-133	432.0	COG2213@1|root,COG2213@2|Bacteria	2|Bacteria	G	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
CSH2_k127_3686160_1	761193.Runsl_0263	3.449e-20	90.0	COG0614@1|root,COG0614@2|Bacteria,4NQYJ@976|Bacteroidetes,47RQY@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CSH2_k127_3686160_0	1202532.FF52_13461	1.229e-26	117.0	2CJ7C@1|root,32ZYU@2|Bacteria,4NUT6@976|Bacteroidetes,1I538@117743|Flavobacteriia,2NV0V@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3686160_2	1122179.KB890454_gene2975	7.331e-14	82.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CSH2_k127_3698073_0	1123248.KB893318_gene4185	9.91e-96	316.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,1IPQJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CSH2_k127_3698073_1	1123248.KB893318_gene4186	8.286e-64	222.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IP9C@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CSH2_k127_3709053_0	1500281.JQKZ01000005_gene4012	3.421e-48	175.0	COG3409@1|root,COG3409@2|Bacteria,4P2ER@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl hydrolase family 46	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_46
CSH2_k127_3709053_1	1239962.C943_02198	7.383e-13	74.0	2C25Y@1|root,3399H@2|Bacteria,4NXDI@976|Bacteroidetes,47SDB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_371308_1	1123248.KB893381_gene1014	2.549e-40	160.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IPR2@117747|Sphingobacteriia	976|Bacteroidetes	NU	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CSH2_k127_371308_0	1267211.KI669560_gene951	1.122e-54	194.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1ISVI@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CSH2_k127_371676_2	925409.KI911562_gene1008	4.305e-25	106.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_16,TPR_8
CSH2_k127_371676_1	1267211.KI669560_gene707	3.411e-79	266.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1ISKP@117747|Sphingobacteriia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CSH2_k127_371676_0	700598.Niako_6016	4.09e-81	282.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1IQZP@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
CSH2_k127_371795_0	1347369.CCAD010000043_gene971	1.335e-144	469.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,1ZBBG@1386|Bacillus	91061|Bacilli	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CSH2_k127_371795_1	1001585.MDS_3357	7.625e-13	72.0	2CWE5@1|root,32SZI@2|Bacteria,1NFS7@1224|Proteobacteria,1SP7U@1236|Gammaproteobacteria,1YJP5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3718352_1	1408473.JHXO01000013_gene563	4.348e-17	85.0	COG2966@1|root,COG2966@2|Bacteria,4NIU3@976|Bacteroidetes,2G2IZ@200643|Bacteroidia	976|Bacteroidetes	S	COGs COG2966 conserved	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
CSH2_k127_3718352_0	1123248.KB893370_gene5146	4.401e-26	112.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes	976|Bacteroidetes	I	Biotin carboxyl carrier protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
CSH2_k127_3718645_2	714943.Mucpa_5247	1.153e-16	81.0	COG0375@1|root,COG0375@2|Bacteria,4NWR5@976|Bacteroidetes,1ITXG@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0375 Zn finger protein HypA HybF (possibly regulating hydrogenase expression)	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
CSH2_k127_3718645_0	700598.Niako_1264	2.207e-197	620.0	COG1740@1|root,COG1740@2|Bacteria,4NK1F@976|Bacteroidetes,1IRKT@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1740 Ni Fe-hydrogenase I small subunit	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
CSH2_k127_3718645_1	700598.Niako_1263	4.284e-18	83.0	COG0374@1|root,COG0374@2|Bacteria,4NJIP@976|Bacteroidetes,1IPFW@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG0374 Ni Fe-hydrogenase I large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
CSH2_k127_3719276_1	700598.Niako_6977	1.684e-173	551.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1IQ1H@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
CSH2_k127_3719276_2	925409.KI911562_gene806	6.049e-166	524.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1INWY@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CSH2_k127_3719276_4	714943.Mucpa_0046	2.886e-100	332.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1IQ9Q@117747|Sphingobacteriia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CSH2_k127_3719276_0	504472.Slin_0217	1.162e-225	705.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,47M8Z@768503|Cytophagia	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CSH2_k127_3719276_3	929713.NIASO_07860	1.246e-105	351.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CSH2_k127_3731091_0	1150600.ADIARSV_2280	4.844e-80	274.0	COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,1IQHM@117747|Sphingobacteriia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CSH2_k127_3731091_1	1305737.JAFX01000001_gene1993	6.069e-70	243.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia	976|Bacteroidetes	O	membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CSH2_k127_3735487_1	1267211.KI669560_gene314	1.908e-15	78.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3735487_0	1123037.AUDE01000041_gene1243	5.655e-44	169.0	COG0582@1|root,COG0582@2|Bacteria,4NS70@976|Bacteroidetes,1I4DE@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CSH2_k127_3735963_1	316274.Haur_1457	1.608e-56	205.0	COG2135@1|root,COG2135@2|Bacteria,2G74X@200795|Chloroflexi,377BN@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CSH2_k127_3735963_0	929713.NIASO_03250	2.937e-87	292.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CSH2_k127_3738555_1	1317122.ATO12_07365	3.405e-12	71.0	COG3595@1|root,COG3595@2|Bacteria,4NW0T@976|Bacteroidetes,1IJ53@117743|Flavobacteriia,2YHRI@290174|Aquimarina	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CSH2_k127_3738555_0	1123248.KB893337_gene2490	1.98e-90	304.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1ISM8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Sulfite exporter TauE SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CSH2_k127_3750440_3	1123248.KB893316_gene4544	3.015e-09	58.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1INY5@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CSH2_k127_3750440_1	929713.NIASO_19065	1.758e-75	261.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1IPVG@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CSH2_k127_3750440_0	700598.Niako_0360	1.262e-85	289.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1IS9C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CSH2_k127_3750440_2	700598.Niako_0362	1.71e-47	171.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1IP5T@117747|Sphingobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CSH2_k127_3758831_0	385682.AFSL01000089_gene937	3.049e-198	623.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,3XJJ7@558415|Marinilabiliaceae	976|Bacteroidetes	J	DALR_2	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
CSH2_k127_3758831_1	861299.J421_4065	8.287e-09	57.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	choD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
CSH2_k127_3760837_1	929713.NIASO_10600	4.685e-70	244.0	COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,1IS83@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CSH2_k127_3760837_0	929713.NIASO_10595	1.552e-171	546.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CSH2_k127_3767965_0	1267211.KI669560_gene2581	5.435e-71	243.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,1IS68@117747|Sphingobacteriia	976|Bacteroidetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
CSH2_k127_3767965_1	1267211.KI669560_gene2394	1.286e-70	242.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1INS9@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CSH2_k127_3770948_0	1267211.KI669560_gene2528	0.0	1174.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CSH2_k127_3770948_2	1123248.KB893326_gene1400	1.277e-98	327.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1IQDU@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CSH2_k127_3770948_1	700598.Niako_0139	4.356e-119	389.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CSH2_k127_3770948_3	1121481.AUAS01000002_gene3556	3.352e-22	103.0	COG5266@1|root,COG5266@2|Bacteria,4NQ8X@976|Bacteroidetes,47QXS@768503|Cytophagia	976|Bacteroidetes	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
CSH2_k127_3774717_0	867902.Ornrh_0091	3.87e-164	521.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CSH2_k127_3778273_0	700598.Niako_6863	4.813e-199	627.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1INQA@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CSH2_k127_3778273_2	1185876.BN8_03018	1.206e-58	209.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,47PZ0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CSH2_k127_3778273_1	925409.KI911562_gene1174	2.502e-133	430.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CSH2_k127_3778273_3	929713.NIASO_19370	5.879e-42	157.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1IZAC@117747|Sphingobacteriia	976|Bacteroidetes	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
CSH2_k127_3781229_0	866536.Belba_1629	1.171e-91	312.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M3Z@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CSH2_k127_3783670_1	1267211.KI669560_gene72	5.162e-23	101.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_3783670_0	391596.PBAL39_12232	1.384e-114	392.0	COG2887@1|root,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1J0H9@117747|Sphingobacteriia	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CSH2_k127_3785024_1	679937.Bcop_0823	3.576e-42	158.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,2FT2Q@200643|Bacteroidia,4AQK2@815|Bacteroidaceae	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CSH2_k127_3785024_0	925409.KI911562_gene1864	8.715e-114	371.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CSH2_k127_3788591_0	398720.MED217_12314	2.667e-260	816.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia,2XI0X@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_3791285_0	1267211.KI669560_gene398	3.995e-205	648.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVD8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_3795744_2	1123248.KB893381_gene1096	4.432e-44	162.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1IS1J@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CSH2_k127_3795744_0	1267211.KI669560_gene2339	1.055e-116	381.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1IPE4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CSH2_k127_3795744_1	700598.Niako_4939	5.769e-87	287.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1IRUT@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CSH2_k127_379663_1	1048983.EL17_01615	6.331e-22	99.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CSH2_k127_379663_0	760192.Halhy_0006	6.754e-25	109.0	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,1J13K@117747|Sphingobacteriia	976|Bacteroidetes	P	FixH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
CSH2_k127_379663_2	1121899.Q764_10230	1.1e-19	92.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia,2NSG1@237|Flavobacterium	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CSH2_k127_3799373_0	926562.Oweho_2942	3.809e-92	310.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia,2PAHE@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
CSH2_k127_3800924_2	883096.HMPREF9699_00133	1.455e-09	62.0	2DQVY@1|root,338ZT@2|Bacteria,4NVHS@976|Bacteroidetes,1I6PR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3800924_0	700598.Niako_6569	1.911e-111	366.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1IPPM@117747|Sphingobacteriia	976|Bacteroidetes	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
CSH2_k127_3800924_3	1492737.FEM08_11330	0.0001815	51.0	COG2353@1|root,COG2353@2|Bacteria,4NWWE@976|Bacteroidetes,1IFHC@117743|Flavobacteriia,2NW8B@237|Flavobacterium	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3800924_1	398720.MED217_13169	5.317e-13	70.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,1HXK7@117743|Flavobacteriia,2XJZD@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3801371_3	929556.Solca_3212	1.502e-14	73.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,1IR9X@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	ykoT	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CSH2_k127_3801371_0	700598.Niako_5603	1.993e-225	704.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1IQYP@117747|Sphingobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CSH2_k127_3801371_1	700598.Niako_5601	6.199e-23	104.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1IPYM@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM chorismate binding	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
CSH2_k127_3809069_0	700598.Niako_7075	5.143e-109	360.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CSH2_k127_3809069_1	925409.KI911562_gene199	6.842e-47	175.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CSH2_k127_3816468_0	1267211.KI669560_gene1963	1.492e-136	439.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1IQUN@117747|Sphingobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CSH2_k127_3816468_1	925409.KI911562_gene2091	1.878e-56	198.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1ISA4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CSH2_k127_3817768_1	1123057.P872_07695	5.652e-36	144.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3817768_0	1267211.KI669560_gene1618	2.143e-243	760.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1ISNT@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S10	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CSH2_k127_3818697_2	700598.Niako_2199	1.003e-32	127.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1IR41@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CSH2_k127_3818697_1	700598.Niako_2699	1.106e-95	326.0	COG0639@1|root,COG1225@1|root,COG0639@2|Bacteria,COG1225@2|Bacteria,4NME8@976|Bacteroidetes,1IUY5@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CSH2_k127_3818697_0	925409.KI911562_gene2120	2.385e-127	411.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1INMG@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CSH2_k127_3820906_0	925409.KI911562_gene815	7.772e-14	71.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,1ISA7@117747|Sphingobacteriia	976|Bacteroidetes	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
CSH2_k127_3821582_1	1157490.EL26_02225	5.668e-08	62.0	COG4430@1|root,COG4430@2|Bacteria,1VJJF@1239|Firmicutes,4IRZ2@91061|Bacilli	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
CSH2_k127_3821582_0	742766.HMPREF9455_01730	1.331e-106	354.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CSH2_k127_3823579_0	1122176.KB903542_gene399	6.373e-31	132.0	COG3391@1|root,COG3391@2|Bacteria,4NZAU@976|Bacteroidetes	976|Bacteroidetes	DZ	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3823579_1	1089549.AZUQ01000001_gene1944	6.605e-08	54.0	COG3502@1|root,COG3502@2|Bacteria,2GQK6@201174|Actinobacteria,4EZ3H@85014|Glycomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
CSH2_k127_382723_1	485918.Cpin_3087	1.071e-32	128.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1IUBT@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CSH2_k127_382723_0	1267211.KI669560_gene1593	2.845e-96	319.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,1INU3@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CSH2_k127_3829730_0	700598.Niako_1029	1.887e-117	386.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IWD6@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_3834075_1	1484460.JSWG01000011_gene1711	1.021e-113	377.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CSH2_k127_3834075_0	925409.KI911562_gene282	8.294e-290	898.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NEXG@976|Bacteroidetes,1IPN6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CSH2_k127_3841894_2	595460.RRSWK_05050	7.963e-17	83.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CSH2_k127_3841894_0	595460.RRSWK_05050	1.201e-93	325.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CSH2_k127_3841894_1	525257.HMPREF0204_15211	3.768e-31	126.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,1I4DC@117743|Flavobacteriia,3ZSDU@59732|Chryseobacterium	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CSH2_k127_3844715_1	1123248.KB893316_gene4589	3.806e-19	91.0	COG1640@1|root,COG1640@2|Bacteria,4NF7Z@976|Bacteroidetes,1IPKN@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	CBM_20,Glyco_hydro_77
CSH2_k127_3844715_0	1267211.KI669560_gene2176	1.415e-99	329.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CSH2_k127_384851_0	1123248.KB893314_gene3632	8.523e-126	419.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CSH2_k127_3851178_0	1122605.KB893643_gene602	3.852e-316	970.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CSH2_k127_3865943_2	1408813.AYMG01000011_gene760	2.758e-41	157.0	COG0739@1|root,COG0739@2|Bacteria,4NN4Q@976|Bacteroidetes,1ISDJ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CSH2_k127_3865943_0	1166018.FAES_2905	2.315e-193	610.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,47JBV@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CSH2_k127_3865943_1	485918.Cpin_2750	1.088e-52	190.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IRKC@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_3872771_1	1267211.KI669560_gene2598	6.597e-36	138.0	2EGEP@1|root,33A6N@2|Bacteria,4NXT1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000	-	-	-	MIase
CSH2_k127_3872771_0	1121957.ATVL01000007_gene2141	2.899e-58	209.0	COG3393@1|root,COG3393@2|Bacteria,4PKIF@976|Bacteroidetes,47UQZ@768503|Cytophagia	976|Bacteroidetes	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
CSH2_k127_3872771_2	1227739.Hsw_1733	7.538e-15	76.0	COG0500@1|root,COG0500@2|Bacteria,4PM8S@976|Bacteroidetes,47TA3@768503|Cytophagia	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31,NodS
CSH2_k127_3880835_0	28072.Nos7524_1682	2.039e-131	431.0	COG2303@1|root,COG2303@2|Bacteria,1G5DG@1117|Cyanobacteria,1HRGW@1161|Nostocales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CSH2_k127_388427_0	929713.NIASO_05550	1.854e-204	640.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1IPB3@117747|Sphingobacteriia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CSH2_k127_3885108_0	1267211.KI669560_gene1907	7.836e-307	945.0	COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,1IPKK@117747|Sphingobacteriia	976|Bacteroidetes	G	COGs COG0058 Glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
CSH2_k127_3885108_1	929556.Solca_3804	2.182e-44	164.0	COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,1IYB6@117747|Sphingobacteriia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
CSH2_k127_3892426_0	1123248.KB893314_gene3545	5.117e-156	499.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,1IQWW@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase domain protein	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
CSH2_k127_3893385_1	1216967.L100_13295	3.665e-13	72.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1HXDX@117743|Flavobacteriia,34PVF@308865|Elizabethkingia	976|Bacteroidetes	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CSH2_k127_3893385_0	700598.Niako_5621	1.012e-50	192.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,1IU2K@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3895023_2	1267211.KI669560_gene1231	2.654e-22	96.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CSH2_k127_3895023_1	525373.HMPREF0766_10801	2.877e-29	122.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1ISS3@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
CSH2_k127_3895023_0	860228.Ccan_10730	1.947e-79	269.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia,1EREB@1016|Capnocytophaga	976|Bacteroidetes	H	Formyltetrahydrofolate synthetase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CSH2_k127_3897227_2	1267211.KI669560_gene724	2.847e-56	199.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1IQWM@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
CSH2_k127_3897227_0	700598.Niako_6515	9.545e-159	505.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes,1IRY2@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
CSH2_k127_3897227_3	243231.GSU1840	2.701e-16	89.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
CSH2_k127_3897227_1	1380600.AUYN01000009_gene1441	1.908e-58	207.0	2DURI@1|root,33RWQ@2|Bacteria,4P0RV@976|Bacteroidetes,1I8FK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3900072_0	700598.Niako_7221	4.526e-53	189.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CSH2_k127_3900072_1	700598.Niako_7222	6.096e-42	158.0	2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3900504_0	1122605.KB893629_gene4169	8.913e-58	210.0	COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1IP90@117747|Sphingobacteriia	976|Bacteroidetes	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CSH2_k127_3900504_1	471854.Dfer_2431	1.047e-24	105.0	2DQR8@1|root,33877@2|Bacteria,4NWHC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3901521_1	485918.Cpin_0408	1.046e-10	63.0	COG3291@1|root,COG3291@2|Bacteria,4NQ3X@976|Bacteroidetes,1IXCU@117747|Sphingobacteriia	976|Bacteroidetes	M	Legume lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Lectin_legB,PKD
CSH2_k127_3901521_0	700598.Niako_0824	1.112e-104	357.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
CSH2_k127_3913229_0	700598.Niako_7325	5.95e-51	193.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IRV2@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
CSH2_k127_3915197_0	1121440.AUMA01000011_gene2351	3.846e-42	161.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CSH2_k127_3915197_1	1121011.AUCB01000002_gene377	0.0001065	50.0	COG0438@1|root,COG0438@2|Bacteria,4NPYF@976|Bacteroidetes,1I4W8@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CSH2_k127_3919898_1	760192.Halhy_5362	1.686e-06	51.0	COG2911@1|root,COG2911@2|Bacteria,4PJD2@976|Bacteroidetes,1J024@117747|Sphingobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CSH2_k127_3919898_0	378806.STAUR_2857	2.444e-20	99.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CSH2_k127_3922934_3	1123248.KB893316_gene4691	6.686e-32	133.0	COG1345@1|root,COG2374@1|root,COG3342@1|root,COG5492@1|root,COG1345@2|Bacteria,COG2374@2|Bacteria,COG3342@2|Bacteria,COG5492@2|Bacteria,4PKUW@976|Bacteroidetes,1J11X@117747|Sphingobacteriia	976|Bacteroidetes	N	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3922934_0	925409.KI911562_gene2297	6.485e-182	575.0	COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1IP6F@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CSH2_k127_3922934_2	1250232.JQNJ01000001_gene2112	2.946e-46	168.0	2C82G@1|root,32RK9@2|Bacteria,4NSXV@976|Bacteroidetes,1I466@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CSH2_k127_3922934_1	504472.Slin_3565	1.377e-99	333.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,47P3T@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CSH2_k127_3932016_0	700598.Niako_4055	8.325e-138	444.0	COG2267@1|root,COG2267@2|Bacteria,4NFIJ@976|Bacteroidetes,1IQBD@117747|Sphingobacteriia	976|Bacteroidetes	I	Serine aminopeptidase, S33	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CSH2_k127_3940915_0	1267211.KI669560_gene1365	7.002e-196	617.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CSH2_k127_3950232_1	1123248.KB893329_gene4488	1.364e-79	272.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CSH2_k127_3950232_0	925409.KI911562_gene108	5.632e-171	542.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CSH2_k127_3953681_0	1267211.KI669560_gene1001	2.347e-165	527.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1IQPQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CSH2_k127_3954339_0	700598.Niako_6489	1.215e-75	258.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,1IRYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, asnc family	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CSH2_k127_3954339_1	700598.Niako_5758	3.437e-11	74.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1ISX9@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CSH2_k127_3957672_0	1150600.ADIARSV_3651	0.0	1030.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1INUX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_3957672_1	1123248.KB893326_gene1298	1.676e-65	230.0	COG2755@1|root,COG2755@2|Bacteria,4NMGQ@976|Bacteroidetes,1IXI7@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CSH2_k127_3957672_2	1270196.JCKI01000006_gene2741	2.254e-46	168.0	COG3507@1|root,COG3507@2|Bacteria,4NEMG@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43,fn3
CSH2_k127_3958059_0	700598.Niako_2168	5.293e-92	308.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1IPGF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CSH2_k127_3966238_0	203275.BFO_2003	1.8e-138	451.0	COG0507@1|root,COG0514@1|root,COG0507@2|Bacteria,COG0514@2|Bacteria,4NF6J@976|Bacteroidetes,2FM19@200643|Bacteroidia,22X68@171551|Porphyromonadaceae	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	uvrD2	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
CSH2_k127_3966238_1	1123248.KB893322_gene588	8.646e-73	248.0	COG1028@1|root,COG1028@2|Bacteria,4NIAZ@976|Bacteroidetes,1IUVU@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
CSH2_k127_396728_1	700598.Niako_4706	5.289e-26	111.0	2DS3S@1|root,33EDT@2|Bacteria,4NY8U@976|Bacteroidetes,1IUQ6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_396728_0	925409.KI911562_gene13	4.471e-26	110.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CSH2_k127_397110_1	1120966.AUBU01000022_gene3007	6.679e-35	141.0	COG1247@1|root,COG1247@2|Bacteria,4PKCF@976|Bacteroidetes,47SA0@768503|Cytophagia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
CSH2_k127_397110_0	1123248.KB893318_gene4193	1.295e-120	390.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1IT0S@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
CSH2_k127_3975442_1	445961.IW15_17805	5.82e-11	64.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HZJX@117743|Flavobacteriia,3ZUJA@59732|Chryseobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
CSH2_k127_3975442_0	1267211.KI669560_gene1981	6.998e-57	205.0	COG2197@1|root,COG2197@2|Bacteria,4NQVA@976|Bacteroidetes	976|Bacteroidetes	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CSH2_k127_3993481_2	1123277.KB893206_gene3485	1.04e-43	166.0	COG0454@1|root,COG0456@2|Bacteria,4NQSN@976|Bacteroidetes,47Q25@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CSH2_k127_3993481_0	1123248.KB893319_gene4035	1.158e-115	377.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1INZJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CSH2_k127_3993481_1	1267211.KI669560_gene390	6.488e-111	366.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes	976|Bacteroidetes	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CSH2_k127_4002261_0	925409.KI911562_gene1808	6.425e-106	357.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1IPU4@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CSH2_k127_4002261_2	925409.KI911562_gene1797	1.203e-62	224.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1IQKS@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CSH2_k127_4002261_1	1123248.KB893385_gene4842	9.417e-69	249.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1IPP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CSH2_k127_4011439_0	1189612.A33Q_0628	8.903e-128	418.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipoxygenase
CSH2_k127_4011439_1	1189612.A33Q_0627	6.834e-77	265.0	COG0753@1|root,COG0753@2|Bacteria	2|Bacteria	C	catalase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4015079_1	1122605.KB893626_gene2647	7.524e-81	272.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CSH2_k127_4015079_0	700598.Niako_5695	5.507e-114	373.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
CSH2_k127_4015210_0	1123248.KB893385_gene4862	5.242e-97	319.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1INQH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CSH2_k127_4015210_1	700598.Niako_5721	4.625e-50	186.0	COG1587@1|root,COG1587@2|Bacteria,4NNSC@976|Bacteroidetes	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CSH2_k127_401536_1	1121285.AUFK01000009_gene1539	4.23e-13	75.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,1I2T9@117743|Flavobacteriia,3ZRYZ@59732|Chryseobacterium	976|Bacteroidetes	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
CSH2_k127_401536_0	1267211.KI669560_gene1963	5.969e-146	462.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,1IQUN@117747|Sphingobacteriia	976|Bacteroidetes	E	decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CSH2_k127_4015577_0	1123248.KB893331_gene3774	4.005e-140	454.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1IQPD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CSH2_k127_4024536_0	1123248.KB893339_gene2703	1.639e-123	405.0	COG1629@1|root,COG4771@2|Bacteria,4PKRZ@976|Bacteroidetes,1J0Q2@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_4029776_0	700598.Niako_6795	0.0	1121.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1IPPB@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17
CSH2_k127_4038865_0	880070.Cycma_2022	6.606e-101	345.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,47NWS@768503|Cytophagia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
CSH2_k127_4038865_1	1120951.AUBG01000013_gene2660	3.345e-24	106.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1I2YQ@117743|Flavobacteriia	976|Bacteroidetes	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CSH2_k127_4038865_2	761193.Runsl_1556	1.53e-15	83.0	COG0349@1|root,COG0349@2|Bacteria,4NP62@976|Bacteroidetes,47QTK@768503|Cytophagia	976|Bacteroidetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CSH2_k127_4050873_0	760192.Halhy_1959	8.983e-152	485.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IP4Z@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CSH2_k127_4054971_1	925409.KI911562_gene1507	7.078e-46	169.0	COG0629@1|root,COG0629@2|Bacteria,4PGRJ@976|Bacteroidetes,1IU5E@117747|Sphingobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
CSH2_k127_4054971_0	925409.KI911562_gene1506	7.716e-146	469.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1IQIE@117747|Sphingobacteriia	976|Bacteroidetes	S	FAD-dependent dehydrogenase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
CSH2_k127_4056846_0	1267211.KI669560_gene2301	9.171e-126	410.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1IP3J@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	amyB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
CSH2_k127_4056846_1	700598.Niako_0945	2.839e-19	91.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1IQHN@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CSH2_k127_4059640_0	1239962.C943_01039	1.658e-267	824.0	COG2015@1|root,COG2015@2|Bacteria,4NJE2@976|Bacteroidetes	976|Bacteroidetes	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
CSH2_k127_4064956_0	929713.NIASO_09040	1.17e-87	300.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,1IPMP@117747|Sphingobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
CSH2_k127_4064956_1	700598.Niako_2551	3.131e-37	147.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4067561_1	404380.Gbem_1790	1.658e-07	62.0	COG0438@1|root,COG0438@2|Bacteria,1RHQ2@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CSH2_k127_4067561_0	203124.Tery_2853	1.814e-09	62.0	COG0457@1|root,COG4421@1|root,COG0457@2|Bacteria,COG4421@2|Bacteria,1G2V7@1117|Cyanobacteria,1H9R5@1150|Oscillatoriales	1117|Cyanobacteria	G	TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
CSH2_k127_4070066_0	925409.KI911562_gene2960	8.328e-145	466.0	COG0761@1|root,COG0761@2|Bacteria	2|Bacteria	IM	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
CSH2_k127_4070066_1	700598.Niako_4724	8.265e-63	219.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1IRY5@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CSH2_k127_4083240_0	925409.KI911562_gene2669	1.565e-68	243.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CSH2_k127_4083240_1	925409.KI911562_gene2668	2.017e-44	163.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,1IT2H@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CSH2_k127_4088187_1	1123248.KB893332_gene2270	2.284e-106	351.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1IQGU@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CSH2_k127_4088187_0	929713.NIASO_04810	8.09e-180	571.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CSH2_k127_4088187_2	485918.Cpin_6519	2.968e-31	124.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CSH2_k127_4090479_3	323848.Nmul_A0851	1.858e-09	61.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,372DM@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
CSH2_k127_4090479_0	468059.AUHA01000005_gene2450	1.429e-161	516.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IRNA@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CSH2_k127_4090479_1	1107311.Q767_03230	5.523e-65	225.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2NWCA@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CSH2_k127_4090479_2	1123248.KB893337_gene2516	1.619e-60	217.0	COG3291@1|root,COG3291@2|Bacteria,4NV8C@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CSH2_k127_4093929_0	1229276.DI53_2165	4.016e-43	171.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1IR6V@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	recB	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CSH2_k127_4095193_1	1123248.KB893329_gene4481	2.022e-37	145.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IS84@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CSH2_k127_4095193_0	1123248.KB893329_gene4482	1.38e-120	394.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1INNA@117747|Sphingobacteriia	976|Bacteroidetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CSH2_k127_4095193_2	700598.Niako_7317	5.972e-07	53.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,1ITPF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4096108_0	746697.Aeqsu_1820	7.696e-42	168.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes,1I1N3@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CSH2_k127_4097173_0	929562.Emtol_1426	5.282e-161	520.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_4097173_1	761193.Runsl_4234	5.728e-67	235.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_4100113_0	1267211.KI669560_gene83	2.836e-95	324.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IPUE@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
CSH2_k127_410158_0	1267211.KI669560_gene165	1.716e-174	552.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IQD6@117747|Sphingobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CSH2_k127_4103514_2	925409.KI911562_gene523	7.864e-49	186.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes	976|Bacteroidetes	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CSH2_k127_4103514_1	925409.KI911562_gene521	1.588e-88	301.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes,1J13D@117747|Sphingobacteriia	976|Bacteroidetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CSH2_k127_4103514_0	925409.KI911562_gene520	7.757e-91	303.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1INZC@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CSH2_k127_4103514_3	761193.Runsl_4391	2.582e-41	154.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,4NE19@976|Bacteroidetes,47TTE@768503|Cytophagia	976|Bacteroidetes	V	Peptidase C39 family	-	-	-	ko:K20344	ko02010,ko02024,map02010,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CSH2_k127_4109412_1	485918.Cpin_6194	6.098e-17	83.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1INUT@117747|Sphingobacteriia	976|Bacteroidetes	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CSH2_k127_4109412_0	1123248.KB893326_gene1423	3.09e-156	509.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1IP5G@117747|Sphingobacteriia	976|Bacteroidetes	M	OstA-like protein	lptD	-	-	-	-	-	-	-	-	-	-	-	OstA_2
CSH2_k127_411640_0	925409.KI911562_gene2282	1.104e-96	323.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
CSH2_k127_411640_1	1123248.KB893359_gene2056	5.612e-64	221.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1ISFT@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
CSH2_k127_411640_2	925409.KI911562_gene2280	3.687e-21	97.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CSH2_k127_4139016_0	700598.Niako_5720	9.941e-107	355.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1ISWJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
CSH2_k127_4143930_1	1123248.KB893314_gene3579	1.308e-77	261.0	COG0249@1|root,COG0249@2|Bacteria,4NEXA@976|Bacteroidetes,1IPHP@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
CSH2_k127_4143930_0	1492737.FEM08_24380	2.101e-202	640.0	COG4580@1|root,COG4580@2|Bacteria,4NHB0@976|Bacteroidetes,1ICN1@117743|Flavobacteriia,2NTIX@237|Flavobacterium	976|Bacteroidetes	G	LamB porin	-	-	-	ko:K02024	-	-	-	-	ko00000,ko02000	1.B.3.1.1	-	-	LamB
CSH2_k127_4143930_2	700598.Niako_0411	4.931e-58	205.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,1IPA5@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CSH2_k127_4145322_0	1189612.A33Q_1129	5.886e-222	692.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,47N56@768503|Cytophagia	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CSH2_k127_4145322_1	1408813.AYMG01000008_gene4040	1.186e-51	190.0	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,1IX9A@117747|Sphingobacteriia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CSH2_k127_4146956_1	925409.KI911562_gene1075	3.495e-55	199.0	COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,1IYNI@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_C_5,TetR_N
CSH2_k127_4146956_0	1267211.KI669560_gene743	4.379e-103	343.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1IWHK@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CSH2_k127_4151961_0	1499967.BAYZ01000062_gene6036	2.647e-14	87.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_7,TPR_8
CSH2_k127_4153704_0	1089547.KB913013_gene1169	1.099e-111	361.0	COG1482@1|root,COG1482@2|Bacteria,4NGGP@976|Bacteroidetes,47NZ6@768503|Cytophagia	976|Bacteroidetes	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4153704_1	504472.Slin_0967	1.632e-80	271.0	COG2017@1|root,COG2017@2|Bacteria,4NHQH@976|Bacteroidetes,47JMF@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
CSH2_k127_415411_1	468059.AUHA01000003_gene1564	1.45e-43	165.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1IT2V@117747|Sphingobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CSH2_k127_415411_0	700598.Niako_6863	1.344e-57	202.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1INQA@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CSH2_k127_4165779_1	153721.MYP_4368	1.07e-96	318.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CSH2_k127_4165779_0	1267211.KI669560_gene1590	4.209e-133	439.0	COG3203@1|root,COG3203@2|Bacteria,4PMSP@976|Bacteroidetes	976|Bacteroidetes	M	outer membrane porin, OprD family	-	-	-	-	-	-	-	-	-	-	-	-	OprD
CSH2_k127_4165779_2	1120968.AUBX01000014_gene2415	1.675e-26	113.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes	976|Bacteroidetes	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CSH2_k127_4166288_1	1123248.KB893314_gene3650	1.398e-95	315.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CSH2_k127_4166288_4	1089547.KB913013_gene3712	6.67e-25	112.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,47RXN@768503|Cytophagia	976|Bacteroidetes	J	2'-5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CSH2_k127_4166288_0	485918.Cpin_1945	5.766e-237	749.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CSH2_k127_4166288_2	700598.Niako_2630	1.698e-50	183.0	COG4430@1|root,COG4430@2|Bacteria,4NQAJ@976|Bacteroidetes,1IUMF@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
CSH2_k127_4166288_3	1123248.KB893316_gene4532	7.99e-33	130.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,1J0JU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CSH2_k127_4170762_1	929713.NIASO_18205	9.322e-70	241.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1IPMS@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
CSH2_k127_4170762_0	700598.Niako_2007	2.72e-122	406.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1IQ33@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CSH2_k127_4185343_1	1267211.KI669560_gene127	1.958e-82	279.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CSH2_k127_4185343_0	1267211.KI669560_gene128	1.523e-90	302.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1ITKW@117747|Sphingobacteriia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CSH2_k127_4186243_2	929713.NIASO_03990	1.367e-10	70.0	2DPQE@1|root,332Z6@2|Bacteria,4NXFJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4186243_0	1123248.KB893370_gene5005	3.458e-55	198.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1ISX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
CSH2_k127_4186243_1	1123248.KB893370_gene5006	3.071e-20	91.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CSH2_k127_4188917_1	1107311.Q767_08415	0.0009782	49.0	2EA9V@1|root,334E9@2|Bacteria,4NWNM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
CSH2_k127_4188917_0	929713.NIASO_14720	0.0	1364.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CSH2_k127_4190319_0	925409.KI911562_gene2880	1.978e-146	474.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IX43@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CSH2_k127_4194244_0	700598.Niako_2193	2.045e-91	319.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,4NDXY@976|Bacteroidetes,1IPVY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
CSH2_k127_4194421_0	641526.ADIWIN_3653	3.625e-97	332.0	COG1881@1|root,COG1881@2|Bacteria,4NKRU@976|Bacteroidetes,1HZIW@117743|Flavobacteriia	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
CSH2_k127_419547_1	1123248.KB893323_gene1617	2.723e-23	100.0	2DKFZ@1|root,309D6@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
CSH2_k127_419547_0	1123248.KB893314_gene3638	4.577e-102	338.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1IQEQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CSH2_k127_4198075_0	925409.KI911562_gene761	9.76e-137	437.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1INW2@117747|Sphingobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CSH2_k127_4198075_1	761193.Runsl_1795	1.114e-31	128.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
CSH2_k127_4201666_1	592029.DDD_2367	4.72e-50	180.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,3HKV0@363408|Nonlabens	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_4201666_0	1236514.BAKL01000001_gene85	1.712e-108	363.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia,4APPA@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_4204786_0	1267211.KI669560_gene1665	6.379e-102	336.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
CSH2_k127_4204786_1	1499967.BAYZ01000062_gene6036	1.779e-27	117.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_7,TPR_8
CSH2_k127_4209727_1	1123248.KB893323_gene1562	5.269e-84	291.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,1IRY1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CSH2_k127_4209727_2	1189612.A33Q_3426	4.564e-61	214.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CSH2_k127_4209727_0	1270196.JCKI01000008_gene1632	4.625e-131	431.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1INWC@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CSH2_k127_4209727_3	1267211.KI669560_gene1228	1.154e-25	109.0	COG2730@1|root,COG2730@2|Bacteria,4NJFV@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	celC	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CSH2_k127_4216791_0	700598.Niako_4140	2.115e-146	469.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CSH2_k127_4216791_1	1267211.KI669560_gene2219	3.004e-116	379.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1IQTX@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CSH2_k127_4216791_2	485918.Cpin_3761	3.556e-33	133.0	COG3063@1|root,COG3063@2|Bacteria,4PKQM@976|Bacteroidetes,1J0N6@117747|Sphingobacteriia	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CSH2_k127_4216791_3	485918.Cpin_3762	4.329e-14	74.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1IQ7X@117747|Sphingobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
CSH2_k127_4222108_1	319003.Bra1253DRAFT_03074	2.438e-09	69.0	COG4421@1|root,COG4421@2|Bacteria,1N9U5@1224|Proteobacteria,2UG2Z@28211|Alphaproteobacteria,3K1NH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
CSH2_k127_4222108_0	1219084.AP014508_gene863	4.179e-25	108.0	COG0367@1|root,COG0367@2|Bacteria,2GDF1@200918|Thermotogae	200918|Thermotogae	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CSH2_k127_4222385_0	925409.KI911562_gene2165	1.153e-154	494.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CSH2_k127_4230596_1	1267211.KI669560_gene521	1.956e-28	116.0	COG3000@1|root,COG3000@2|Bacteria,4NMKR@976|Bacteroidetes,1ISPG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_4230596_0	925409.KI911562_gene2790	9.369e-29	123.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
CSH2_k127_4231133_0	1123248.KB893326_gene1293	1.8e-199	631.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_4231133_1	1121286.AUMT01000012_gene2847	5.328e-28	117.0	28MFR@1|root,30IJE@2|Bacteria,4PHUF@976|Bacteroidetes,1ICRP@117743|Flavobacteriia,3ZSRQ@59732|Chryseobacterium	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CSH2_k127_4237664_0	929556.Solca_4206	1.951e-100	338.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,1INTJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CSH2_k127_4237664_1	929556.Solca_4205	8.081e-93	310.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPE6@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CSH2_k127_4243200_0	700598.Niako_5676	3.496e-93	314.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1IRJS@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CSH2_k127_4243200_1	1123248.KB893348_gene309	3.423e-81	280.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1IP6P@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CSH2_k127_4246004_0	1123393.KB891316_gene1613	1.415e-36	150.0	2C1AX@1|root,33GUX@2|Bacteria,1MZSH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4264749_0	421072.IO89_01405	1.682e-88	298.0	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia,3HH9K@358033|Chryseobacterium	976|Bacteroidetes	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CSH2_k127_4264749_1	700598.Niako_2487	3.231e-43	163.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
CSH2_k127_427443_1	1267211.KI669560_gene2683	1.744e-55	196.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1INYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CSH2_k127_427443_0	929713.NIASO_07775	2.717e-152	492.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1IQXN@117747|Sphingobacteriia	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CSH2_k127_427830_2	700598.Niako_4591	3.121e-42	158.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISG3@117747|Sphingobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
CSH2_k127_427830_0	925409.KI911562_gene1573	1.029e-143	458.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1IRAS@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CSH2_k127_427830_3	1121481.AUAS01000004_gene1390	3.996e-34	139.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,47QK5@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
CSH2_k127_427830_1	929713.NIASO_02595	5.005e-79	267.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
CSH2_k127_428852_1	1239962.C943_00093	9.311e-46	169.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,47KT5@768503|Cytophagia	976|Bacteroidetes	U	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CSH2_k127_428852_0	1121373.KB903637_gene946	3.267e-122	400.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,47JG3@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CSH2_k127_428852_2	1121904.ARBP01000005_gene4474	1.529e-12	73.0	28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4292391_1	925409.KI911562_gene2299	1.651e-77	261.0	COG2316@1|root,COG2316@2|Bacteria,4NIAC@976|Bacteroidetes	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CSH2_k127_4292391_0	700598.Niako_0985	9.473e-214	668.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_4294320_0	1267211.KI669560_gene96	1.426e-190	598.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_4301456_0	1123248.KB893330_gene395	1.962e-92	315.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1IXKD@117747|Sphingobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
CSH2_k127_4301456_1	925409.KI911562_gene2888	3.536e-54	193.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1IQYY@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CSH2_k127_4303425_1	485918.Cpin_2372	9.416e-14	76.0	COG0438@1|root,COG0438@2|Bacteria,4NI3I@976|Bacteroidetes,1IRMM@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_4303425_0	929713.NIASO_17855	2.043e-205	640.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CSH2_k127_4303425_2	929556.Solca_3548	5.766e-13	71.0	COG0457@1|root,COG0457@2|Bacteria,4PPB4@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4308090_0	1123057.P872_06590	1.085e-77	266.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,47NB9@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CSH2_k127_4308090_1	1123277.KB893194_gene5879	9.652e-44	163.0	COG0607@1|root,COG0607@2|Bacteria,4NR99@976|Bacteroidetes,47SFJ@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4317926_0	1123248.KB893337_gene2461	3.046e-104	350.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1IQ7X@117747|Sphingobacteriia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
CSH2_k127_4317926_1	1298608.JCM18900_1443	1.542e-63	223.0	COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,1S2UY@1236|Gammaproteobacteria,3NKSF@468|Moraxellaceae	1236|Gammaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CSH2_k127_431819_1	1034807.FBFL15_1759	1.247e-59	215.0	COG2304@1|root,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,1HZ8Q@117743|Flavobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_431819_0	1434325.AZQN01000003_gene2368	1.332e-150	491.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_4326758_0	153721.MYP_4380	5.435e-123	398.0	COG2141@1|root,COG2141@2|Bacteria,4NHGI@976|Bacteroidetes,47MJ4@768503|Cytophagia	976|Bacteroidetes	C	Luciferase-like monooxygenase	yhbW	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CSH2_k127_4326758_1	468059.AUHA01000002_gene928	6.958e-14	71.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1IPE8@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
CSH2_k127_4330608_0	1296416.JACB01000029_gene4197	1.229e-126	423.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1HYP7@117743|Flavobacteriia,2YIDG@290174|Aquimarina	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CSH2_k127_4334172_0	925409.KI911562_gene230	1.744e-230	719.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1INMC@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CSH2_k127_4334172_1	925409.KI911562_gene231	1.151e-143	460.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1INNM@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CSH2_k127_4334172_2	700598.Niako_7032	2.582e-59	207.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1ISF1@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CSH2_k127_4339399_1	929562.Emtol_1426	2.036e-79	269.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_4339399_2	485918.Cpin_1614	1.597e-53	190.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1ISQN@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CSH2_k127_4339399_0	925409.KI911562_gene3034	8.49e-109	354.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CSH2_k127_4345597_0	700598.Niako_1050	1.41e-10	71.0	COG1520@1|root,COG4935@1|root,COG1520@2|Bacteria,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes,1IYMI@117747|Sphingobacteriia	976|Bacteroidetes	O	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4345597_1	926562.Oweho_0550	0.0005763	44.0	COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,1HYBV@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	alkB	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
CSH2_k127_4346611_0	1267211.KI669560_gene2702	0.0	1026.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IRF8@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC
CSH2_k127_4375240_0	925409.KI911562_gene1899	1.792e-107	353.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CSH2_k127_4375240_1	929713.NIASO_09635	0.0006879	45.0	2E676@1|root,330VQ@2|Bacteria,4NWHJ@976|Bacteroidetes,1ITZQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4376220_1	1123248.KB893319_gene4019	1.513e-48	178.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1IP2Z@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane protein involved in aromatic hydrocarbon degradation	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
CSH2_k127_4376220_0	700598.Niako_1990	2.175e-57	204.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1IPJH@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CSH2_k127_4377248_0	1131812.JQMS01000001_gene410	1.235e-293	913.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NSID@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_4377248_1	1122605.KB893626_gene2450	1.115e-31	125.0	COG0584@1|root,COG2273@1|root,COG0584@2|Bacteria,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1J1A1@117747|Sphingobacteriia	976|Bacteroidetes	CG	Beta-glucan synthesis-associated protein (SKN1)	-	-	-	-	-	-	-	-	-	-	-	-	GDPD,Glyco_hydro_16
CSH2_k127_4383195_0	1267211.KI669560_gene693	1.524e-128	420.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,1INUS@117747|Sphingobacteriia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CSH2_k127_4383195_1	1166018.FAES_5144	7.834e-42	164.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_4396199_2	463191.SSEG_01215	7.855e-07	53.0	COG3669@1|root,COG3669@2|Bacteria,2HUEI@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C,NPCBM_assoc
CSH2_k127_4396199_0	880071.Fleli_3464	1.175e-121	397.0	COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,47JGK@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory helix-turn-helix protein, lysR family	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CSH2_k127_4396199_1	1131812.JQMS01000001_gene1221	4.276e-12	71.0	COG2010@1|root,COG2010@2|Bacteria,4PCRX@976|Bacteroidetes,1IDAA@117743|Flavobacteriia,2NXVD@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_439709_0	1121481.AUAS01000007_gene1156	2.098e-07	62.0	COG5295@1|root,COG5295@2|Bacteria,4PPK6@976|Bacteroidetes	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4397518_2	1120965.AUBV01000004_gene977	1.043e-74	252.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,47XGE@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CSH2_k127_4397518_0	1189612.A33Q_2410	6.031e-138	447.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47NWH@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	pbpE	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CSH2_k127_4397518_1	700598.Niako_4488	2.26e-108	355.0	COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,1IS5S@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CSH2_k127_4404217_0	700598.Niako_6331	1.479e-119	393.0	COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,1INNP@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CSH2_k127_4405640_0	925409.KI911562_gene1862	2.878e-261	814.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1IR7Y@117747|Sphingobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CSH2_k127_4408475_0	1267211.KI669560_gene2677	4.948e-93	311.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_4408475_1	700598.Niako_2721	1.294e-75	265.0	COG0392@1|root,COG0392@2|Bacteria,4NMZ1@976|Bacteroidetes,1IRX8@117747|Sphingobacteriia	976|Bacteroidetes	O	Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CSH2_k127_4408551_7	485918.Cpin_1055	1.318e-20	91.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CSH2_k127_4408551_0	761193.Runsl_4070	4.123e-155	502.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,47K31@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
CSH2_k127_4408551_5	925409.KI911562_gene905	9.478e-28	117.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1IT9C@117747|Sphingobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CSH2_k127_4408551_2	1122605.KB893626_gene2806	4.659e-41	153.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CSH2_k127_4408551_1	925409.KI911562_gene485	5.786e-117	383.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1IQ92@117747|Sphingobacteriia	976|Bacteroidetes	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CSH2_k127_4408551_6	985867.AEWF01000001_gene1830	3.628e-21	95.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,2UGR1@28211|Alphaproteobacteria,47GPN@766|Rickettsiales	766|Rickettsiales	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CSH2_k127_4408551_3	1270196.JCKI01000005_gene2840	7.307e-36	145.0	COG0251@1|root,COG0251@2|Bacteria,4NMXE@976|Bacteroidetes,1IZFP@117747|Sphingobacteriia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CSH2_k127_4408551_4	1218103.CIN01S_20_00140	2.384e-31	137.0	COG0018@1|root,COG4675@1|root,COG0018@2|Bacteria,COG4675@2|Bacteria,4PPDP@976|Bacteroidetes,1IKJ5@117743|Flavobacteriia,3ZURU@59732|Chryseobacterium	976|Bacteroidetes	J	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4411023_1	1236959.BAMT01000006_gene422	2.958e-11	64.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,2VJK9@28216|Betaproteobacteria,2KKXD@206350|Nitrosomonadales	206350|Nitrosomonadales	O	ResB-like family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CSH2_k127_4411023_0	1123392.AQWL01000002_gene1939	2.831e-132	427.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,1KRWH@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CSH2_k127_4411413_0	929713.NIASO_13385	7.569e-174	550.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CSH2_k127_4413667_0	7719.XP_009858154.1	0.0008025	51.0	KOG0266@1|root,KOG3213@1|root,KOG0266@2759|Eukaryota,KOG3213@2759|Eukaryota,38BCA@33154|Opisthokonta,3BDVV@33208|Metazoa,3CRRI@33213|Bilateria,486I0@7711|Chordata	33208|Metazoa	K	WD repeat domain 90	WDR90	-	-	-	-	-	-	-	-	-	-	-	DUF667,Nup160,WD40
CSH2_k127_4419043_0	700598.Niako_0983	1.122e-124	407.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1IQ05@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CSH2_k127_4419043_1	925409.KI911562_gene2240	1.884e-27	115.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose reductase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CSH2_k127_4419398_0	925409.KI911562_gene732	1.492e-165	528.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1IQZ5@117747|Sphingobacteriia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CSH2_k127_4419398_1	925409.KI911562_gene731	3.805e-135	434.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CSH2_k127_4419398_2	761193.Runsl_3454	2.914e-16	80.0	2CH44@1|root,33JG7@2|Bacteria,4PC1R@976|Bacteroidetes,47WPG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4420295_0	700598.Niako_5153	6.626e-174	551.0	COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CSH2_k127_4422010_0	765912.Thimo_3227	4.901e-34	145.0	COG0507@1|root,COG0507@2|Bacteria,1QCFP@1224|Proteobacteria,1S1GX@1236|Gammaproteobacteria,1WXXU@135613|Chromatiales	135613|Chromatiales	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	HRDC,HTH_40,Herpes_Helicase,PIF1
CSH2_k127_4422759_0	925409.KI911562_gene1393	9.634e-230	717.0	COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IPYF@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65 central catalytic domain	kojP	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65N,Glyco_hydro_65m
CSH2_k127_442386_1	153721.MYP_3633	2.077e-07	52.0	COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,47QUD@768503|Cytophagia	976|Bacteroidetes	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CSH2_k127_442386_0	929703.KE386491_gene4114	1.097e-174	558.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47JE7@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
CSH2_k127_4425704_1	700598.Niako_6877	5.078e-33	129.0	COG0491@1|root,COG0491@2|Bacteria,4NHW8@976|Bacteroidetes,1IQ1J@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CSH2_k127_4425704_0	925409.KI911562_gene362	2.449e-76	261.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1INPB@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CSH2_k127_4428710_1	1123248.KB893385_gene4801	4.302e-60	210.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1ISPN@117747|Sphingobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CSH2_k127_4428710_0	1122605.KB893643_gene836	2.509e-116	379.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CSH2_k127_4432041_1	1189620.AJXL01000013_gene2449	2.415e-30	121.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia,2NUVN@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CSH2_k127_4432041_0	1150600.ADIARSV_1360	2.349e-88	298.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1IPEW@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CSH2_k127_4432101_0	700598.Niako_6439	4.742e-103	353.0	COG1629@1|root,COG4771@2|Bacteria,4PN3U@976|Bacteroidetes,1J0TZ@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3
CSH2_k127_4432101_1	925409.KI911562_gene440	2.246e-66	229.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
CSH2_k127_4436551_0	1270193.JARP01000007_gene276	1.212e-140	453.0	COG1052@1|root,COG1052@2|Bacteria,4NF1R@976|Bacteroidetes,1HZJN@117743|Flavobacteriia,2NSY7@237|Flavobacterium	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CSH2_k127_4440332_1	700598.Niako_3506	2.815e-17	83.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,4NEK3@976|Bacteroidetes,1INMR@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
CSH2_k127_4440332_2	95619.PM1_0225965	0.0002094	51.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria,1SZYB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
CSH2_k127_4440332_0	485918.Cpin_6602	1.859e-23	100.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CSH2_k127_4441574_0	1144313.PMI10_02610	1.647e-104	349.0	COG2307@1|root,COG2307@2|Bacteria,4NHIB@976|Bacteroidetes,1I040@117743|Flavobacteriia,2NUS5@237|Flavobacterium	976|Bacteroidetes	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CSH2_k127_4441574_1	485918.Cpin_5583	2.377e-24	104.0	COG1305@1|root,COG1305@2|Bacteria,4NF4N@976|Bacteroidetes,1IPWA@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG1305 Transglutaminase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
CSH2_k127_4441633_1	1340493.JNIF01000004_gene273	2.443e-06	50.0	COG0531@1|root,COG0531@2|Bacteria,3Y3SZ@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CSH2_k127_4441633_0	929713.NIASO_04310	5.954e-125	403.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1IQCX@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CSH2_k127_4443370_0	700598.Niako_6470	5.768e-278	857.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1INKZ@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CSH2_k127_4448995_0	700598.Niako_1939	1.476e-151	487.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CSH2_k127_4448995_1	1250006.JHZZ01000001_gene2567	0.000154	49.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia,3VWH6@52959|Polaribacter	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
CSH2_k127_4449871_2	929562.Emtol_3888	3.251e-39	149.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,47JSY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CSH2_k127_4449871_1	925409.KI911562_gene2912	1.415e-135	437.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1IQIJ@117747|Sphingobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CSH2_k127_4449871_0	925409.KI911562_gene1120	1.065e-218	687.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,1IV8P@117747|Sphingobacteriia	976|Bacteroidetes	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
CSH2_k127_4449871_3	925409.KI911562_gene1121	1.786e-35	136.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,1IXAV@117747|Sphingobacteriia	976|Bacteroidetes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
CSH2_k127_4451785_0	1123248.KB893319_gene4007	1.073e-60	213.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CSH2_k127_4451785_1	1267211.KI669560_gene2053	5.814e-50	185.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CSH2_k127_4452424_0	1267211.KI669560_gene2068	1.701e-62	218.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1IPIU@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
CSH2_k127_4452424_1	1121859.KB890756_gene1403	4.647e-46	187.0	28QY8@1|root,2ZDDB@2|Bacteria,4NN2K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4454517_0	929562.Emtol_0813	2.16e-57	212.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,47P2M@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PKD
CSH2_k127_4454517_1	925409.KI911562_gene2317	2.946e-18	84.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1ITF1@117747|Sphingobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CSH2_k127_4457167_1	925409.KI911562_gene2253	5.546e-35	136.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CSH2_k127_4457167_0	700598.Niako_4415	5.846e-68	243.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1IP77@117747|Sphingobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CSH2_k127_4462194_0	925409.KI911562_gene1982	3.59e-306	943.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,1IP8F@117747|Sphingobacteriia	976|Bacteroidetes	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CSH2_k127_4462323_2	700598.Niako_0894	8.886e-85	282.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CSH2_k127_4462323_0	1267211.KI669560_gene1526	0.0	1219.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1IQ4F@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CSH2_k127_4462323_1	1267211.KI669560_gene1527	7.2e-89	299.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1ISIA@117747|Sphingobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
CSH2_k127_4463199_0	1122605.KB893646_gene69	3.002e-139	452.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1IREB@117747|Sphingobacteriia	976|Bacteroidetes	M	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_4463199_1	1166018.FAES_3561	1.229e-95	319.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y7H@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	-	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_4463280_0	925409.KI911562_gene85	5.102e-225	704.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1IPBW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CSH2_k127_4463280_1	1123248.KB893320_gene3871	7.5e-121	394.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
CSH2_k127_4464460_2	1089547.KB913013_gene3855	3.152e-23	100.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,47KMZ@768503|Cytophagia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CSH2_k127_4464460_0	925409.KI911562_gene1521	7.618e-206	648.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
CSH2_k127_4464460_1	929556.Solca_3575	2.57e-58	209.0	COG1216@1|root,COG1216@2|Bacteria,4NGEQ@976|Bacteroidetes,1IPXG@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_4467548_0	700598.Niako_2199	1.801e-248	772.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1IR41@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CSH2_k127_4467548_1	468059.AUHA01000002_gene911	3.58e-111	372.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4PHWS@976|Bacteroidetes,1IYDI@117747|Sphingobacteriia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_4468449_0	1267211.KI669560_gene848	3.836e-101	341.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1IQJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Outer membrane cobalamin receptor protein	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
CSH2_k127_4482389_0	1123248.KB893316_gene4624	1.572e-63	229.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,1IS5U@117747|Sphingobacteriia	976|Bacteroidetes	K	MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
CSH2_k127_4482389_1	1123248.KB893316_gene4625	5.721e-63	217.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CSH2_k127_4485271_1	1120965.AUBV01000014_gene1243	5.726e-193	607.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CSH2_k127_4485271_0	1358423.N180_16420	3.301e-198	625.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1IRNQ@117747|Sphingobacteriia	976|Bacteroidetes	F	Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CSH2_k127_4485821_0	700598.Niako_6421	1.14e-158	504.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,1IR2B@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CSH2_k127_4485821_1	1313421.JHBV01000010_gene4163	3.819e-24	109.0	COG2267@1|root,COG2267@2|Bacteria,4NK38@976|Bacteroidetes	976|Bacteroidetes	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
CSH2_k127_4494091_2	29495.EA26_02055	4.165e-35	134.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1XU3P@135623|Vibrionales	135623|Vibrionales	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CSH2_k127_4494091_1	266748.HY04_10215	5.373e-67	232.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia,3ZNQ9@59732|Chryseobacterium	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CSH2_k127_4494091_0	925409.KI911562_gene1123	1.855e-189	595.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CSH2_k127_4494091_3	760192.Halhy_0262	5.641e-26	113.0	COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,1IPCS@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
CSH2_k127_4494782_1	1122621.ATZA01000011_gene416	1.286e-21	95.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CSH2_k127_4494782_0	925409.KI911562_gene2192	4.386e-79	268.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1IPSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CSH2_k127_4497658_0	1123234.AUKI01000020_gene664	1.112e-66	236.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes,1I391@117743|Flavobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CSH2_k127_449938_0	1279009.ADICEAN_00451	5.818e-160	511.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
CSH2_k127_449938_2	485918.Cpin_0682	6.121e-11	64.0	COG2010@1|root,COG2010@2|Bacteria,4PJ6S@976|Bacteroidetes,1IZP1@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_449938_1	700598.Niako_1943	1.244e-49	189.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CSH2_k127_4499790_0	1123248.KB893332_gene2256	1.765e-79	272.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1IP8R@117747|Sphingobacteriia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
CSH2_k127_4499790_1	240016.ABIZ01000001_gene1912	5.029e-58	208.0	COG2764@1|root,COG2764@2|Bacteria,46W8S@74201|Verrucomicrobia,2IWEY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
CSH2_k127_4508922_1	1123248.KB893314_gene3423	2.032e-39	153.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CSH2_k127_4508922_0	1123248.KB893314_gene3422	1.246e-95	325.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CSH2_k127_4509088_0	925409.KI911562_gene2941	2.951e-257	799.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CSH2_k127_4517550_0	700598.Niako_5138	2.151e-120	394.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
CSH2_k127_4523082_0	700598.Niako_6288	1.025e-269	835.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1INSY@117747|Sphingobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CSH2_k127_4523082_1	1237149.C900_03499	8.661e-05	49.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes,47NP5@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CSH2_k127_4523695_1	1288963.ADIS_1886	3.334e-69	241.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CSH2_k127_4523695_0	1450525.JATV01000019_gene2405	7.573e-142	455.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,1I0HW@117743|Flavobacteriia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CSH2_k127_4524056_2	925409.KI911562_gene1104	1.061e-72	247.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1IVGY@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CSH2_k127_4524056_0	1123248.KB893348_gene82	3.914e-90	301.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4524056_1	1123248.KB893348_gene81	1.846e-85	286.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1IQ2V@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
CSH2_k127_453136_0	700598.Niako_6995	2.604e-153	494.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,1J0KY@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_453136_1	700598.Niako_6996	1.122e-07	54.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,1IS13@117747|Sphingobacteriia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CSH2_k127_4542812_0	925409.KI911562_gene2835	2.893e-213	666.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1IR48@117747|Sphingobacteriia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CSH2_k127_4550096_0	760192.Halhy_2333	4.135e-93	314.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1IPF0@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08156	-	-	-	-	ko00000,ko02000	2.A.1.2.14	-	-	MFS_1,Sugar_tr
CSH2_k127_4550096_1	700598.Niako_2006	3.676e-81	273.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CSH2_k127_4555617_1	56780.SYN_02682	1.032e-72	248.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1PDZZ@1224|Proteobacteria,42M63@68525|delta/epsilon subdivisions,2WJDW@28221|Deltaproteobacteria,2MQXM@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
CSH2_k127_4555617_2	572547.Amico_1736	3.452e-56	201.0	COG0640@1|root,COG0640@2|Bacteria,3TAVK@508458|Synergistetes	508458|Synergistetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4555617_0	743722.Sph21_1828	1.193e-160	513.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1IR9A@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CSH2_k127_4555617_3	391598.FBBAL38_02585	3.726e-25	109.0	COG5360@1|root,COG5360@2|Bacteria,4NH16@976|Bacteroidetes,1I0J6@117743|Flavobacteriia	976|Bacteroidetes	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
CSH2_k127_4555659_0	700598.Niako_6291	3.182e-67	244.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4555659_1	700598.Niako_2578	6.766e-49	179.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1IU44@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4556297_1	1122605.KB893629_gene4139	3.202e-37	140.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1INYF@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CSH2_k127_4556297_0	1123277.KB893172_gene843	2.301e-105	351.0	28K2T@1|root,2Z9S3@2|Bacteria,4NJHU@976|Bacteroidetes,47JZI@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
CSH2_k127_4557440_0	1122605.KB893646_gene175	1.077e-34	133.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CSH2_k127_4557440_1	485918.Cpin_4506	8.512e-24	113.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,4NHWG@976|Bacteroidetes,1IRF4@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_4559569_2	1089547.KB913013_gene2308	0.0005938	46.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,47XQX@768503|Cytophagia	976|Bacteroidetes	N	OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CSH2_k127_4559569_1	700598.Niako_2485	1.123e-70	247.0	2DWQN@1|root,341FB@2|Bacteria,4P4AQ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF3575)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3575
CSH2_k127_4559569_0	700598.Niako_6795	9.023e-174	549.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1IPPB@117747|Sphingobacteriia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17
CSH2_k127_4560388_0	925409.KI911562_gene2502	1.819e-251	779.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1IP6T@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CSH2_k127_4563742_1	1267211.KI669560_gene2811	7.33e-22	96.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
CSH2_k127_4563742_0	485918.Cpin_1235	3.509e-34	139.0	COG3063@1|root,COG3063@2|Bacteria,4PKEN@976|Bacteroidetes	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4563742_2	1267211.KI669560_gene2809	1.501e-08	58.0	295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,1IZ1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4570814_1	1492737.FEM08_10300	1.821e-05	46.0	COG2985@1|root,COG2985@2|Bacteria,4NEBW@976|Bacteroidetes,1HZIV@117743|Flavobacteriia,2P0F7@237|Flavobacterium	976|Bacteroidetes	U	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
CSH2_k127_4570814_0	700598.Niako_5814	1.172e-83	288.0	COG0457@1|root,COG0457@2|Bacteria,4NME3@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
CSH2_k127_4579683_0	925409.KI911562_gene2981	4.95e-74	255.0	28KFX@1|root,2ZA1W@2|Bacteria,4P3W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4579683_1	1267211.KI669560_gene1847	1.199e-40	154.0	COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,1ISU6@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CSH2_k127_4580090_0	929703.KE386491_gene639	1.418e-119	400.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y3K@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_4584538_2	1086011.HJ01_02515	2.484e-26	114.0	2A2MK@1|root,30QZX@2|Bacteria,4P5NJ@976|Bacteroidetes,1IDRG@117743|Flavobacteriia,2NZ12@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4584538_1	1048983.EL17_07940	1.028e-55	203.0	COG0386@1|root,COG0386@2|Bacteria,4NP8C@976|Bacteroidetes,47Q5J@768503|Cytophagia	976|Bacteroidetes	O	Glutathione peroxidase	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CSH2_k127_4584538_0	1048983.EL17_01155	2.191e-88	303.0	COG2220@1|root,COG2220@2|Bacteria,4NI69@976|Bacteroidetes,47K8S@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CSH2_k127_4584538_3	866536.Belba_0618	3.898e-13	74.0	294EW@1|root,2ZRUR@2|Bacteria,4NPA3@976|Bacteroidetes,47PT9@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
CSH2_k127_4597649_0	1123248.KB893314_gene3285	1.342e-107	356.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1IQAC@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CSH2_k127_4599892_1	700598.Niako_1259	0.0001315	44.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CSH2_k127_4599892_0	243233.MCA0768	6.098e-110	364.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,1XDK5@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CSH2_k127_4606169_1	929713.NIASO_00880	1.071e-16	85.0	COG4870@1|root,COG4870@2|Bacteria,4NGK1@976|Bacteroidetes,1INPA@117747|Sphingobacteriia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C1
CSH2_k127_4606169_0	1123248.KB893326_gene1410	6.768e-95	338.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K02014,ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000,ko02042	1.B.14	-	-	Alginate_lyase2,CBM_6,CarbopepD_reg_2,F5_F8_type_C,Plug,Thiol_cytolys_C,Thiol_cytolysin,TonB_dep_Rec
CSH2_k127_460638_0	700598.Niako_6538	9.724e-166	523.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_460638_2	485918.Cpin_0677	4.299e-68	236.0	COG1187@1|root,COG1187@2|Bacteria,4NM4U@976|Bacteroidetes,1IY6P@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CSH2_k127_460638_1	485918.Cpin_0890	6.679e-109	356.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1INQC@117747|Sphingobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CSH2_k127_4613419_1	1033810.HLPCO_001684	3.237e-32	128.0	arCOG10456@1|root,2ZA6T@2|Bacteria,2NRFY@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4613419_0	1123248.KB893330_gene423	4.92e-97	321.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CSH2_k127_4613419_2	1453505.JASY01000012_gene4146	0.0003898	47.0	28N3K@1|root,32XIJ@2|Bacteria,4PKCA@976|Bacteroidetes,1IJ7A@117743|Flavobacteriia,2NV8H@237|Flavobacterium	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
CSH2_k127_461887_1	1218108.KB908297_gene2966	0.0004021	47.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
CSH2_k127_461887_0	1122605.KB893629_gene4089	5.162e-58	217.0	2DB7X@1|root,2Z7P2@2|Bacteria,4NH95@976|Bacteroidetes,1J0CX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4625209_0	925409.KI911562_gene1625	4.642e-80	275.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1ISNC@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CSH2_k127_4625209_1	929713.NIASO_03100	4.841e-25	109.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1ITNI@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
CSH2_k127_4625209_2	1123035.ARLA01000028_gene2259	8.448e-13	68.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1HX5Y@117743|Flavobacteriia,4C399@83612|Psychroflexus	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CSH2_k127_4632250_0	1239962.C943_02231	1.2e-32	130.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4632250_1	1267211.KI669560_gene394	2.315e-17	85.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1IR8K@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CSH2_k127_4634194_0	925409.KI911562_gene1580	1.347e-12	78.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	xlyB	-	3.5.1.28	ko:K01447,ko:K01449,ko:K19224	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	CHAP,LysM,YkuD
CSH2_k127_4637740_1	700598.Niako_6637	1.85e-129	423.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CSH2_k127_4637740_0	925409.KI911562_gene1820	2.443e-285	896.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,4NGF6@976|Bacteroidetes,1IQ4D@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	nhaA	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
CSH2_k127_4637740_2	1434325.AZQN01000004_gene1778	2.13e-07	53.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,47JBH@768503|Cytophagia	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CSH2_k127_463879_0	1123248.KB893348_gene194	3.345e-99	336.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,1IWR7@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_463879_1	1123248.KB893348_gene195	6.481e-86	291.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1ISF2@117747|Sphingobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CSH2_k127_463879_2	1223410.KN050846_gene1253	1.111e-12	74.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes,1I4AH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4645521_0	929562.Emtol_1162	3.674e-227	721.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CSH2_k127_46517_0	925409.KI911562_gene1430	1.148e-210	659.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CSH2_k127_46517_1	700598.Niako_5724	1.828e-132	424.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CSH2_k127_465657_0	313596.RB2501_01061	2.595e-220	688.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1HZ06@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CSH2_k127_465657_1	1168034.FH5T_18130	1.023e-89	302.0	COG0599@1|root,COG0599@2|Bacteria,4NFEI@976|Bacteroidetes,2FSAB@200643|Bacteroidia	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
CSH2_k127_4657420_0	1267211.KI669560_gene722	8.613e-141	449.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CSH2_k127_4677953_1	761193.Runsl_5610	9.174e-18	87.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,4NK01@976|Bacteroidetes,47NT3@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_4677953_0	1047013.AQSP01000142_gene192	3.145e-187	602.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CSH2_k127_4679292_1	700598.Niako_6198	1.326e-77	266.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CSH2_k127_4679292_2	929703.KE386491_gene2306	5.589e-15	76.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes,47SE5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CSH2_k127_4679292_0	1349785.BAUG01000034_gene1915	3.18e-93	311.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,1HX0F@117743|Flavobacteriia	976|Bacteroidetes	O	collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CSH2_k127_4685424_0	700598.Niako_0884	2.816e-116	385.0	COG1119@1|root,COG1119@2|Bacteria,4NEWY@976|Bacteroidetes,1INTA@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type molybdenum transport system ATPase component photorepair protein PhrA	modF	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
CSH2_k127_4687846_1	1267211.KI669560_gene61	1.55e-75	265.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CSH2_k127_4687846_2	700598.Niako_6672	9.383e-49	178.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1ISZW@117747|Sphingobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CSH2_k127_4687846_5	700598.Niako_6673	3.336e-21	101.0	COG1250@1|root,COG1250@2|Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.108,1.1.1.157	ko:K00074,ko:K17735	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N,4HBT_2
CSH2_k127_4687846_3	1123248.KB893319_gene3976	5.215e-42	162.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1IRWM@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CSH2_k127_4687846_4	485918.Cpin_0945	3.241e-30	123.0	COG0640@1|root,COG0640@2|Bacteria,4P4RQ@976|Bacteroidetes,1IYKV@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CSH2_k127_4687846_0	700598.Niako_6676	3.36e-119	388.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CSH2_k127_4710479_0	700598.Niako_7078	1.682e-134	433.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CSH2_k127_4718446_0	1122605.KB893644_gene1481	1.539e-209	654.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1IP1Y@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CSH2_k127_4718446_1	1347342.BN863_23090	2.897e-07	61.0	28KUV@1|root,2ZABI@2|Bacteria,4NKCX@976|Bacteroidetes,1HYVT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CSH2_k127_4721130_0	700598.Niako_1886	2.896e-101	336.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1IQ62@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CSH2_k127_4721130_1	700598.Niako_1885	1.504e-88	296.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1IPKD@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CSH2_k127_4727081_3	1123248.KB893318_gene4156	4.925e-22	102.0	COG4775@1|root,COG4775@2|Bacteria,4NHNW@976|Bacteroidetes,1IWSZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CSH2_k127_4727081_0	1267211.KI669560_gene2483	5.796e-64	222.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1IRUM@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CSH2_k127_4727081_2	1122605.KB893644_gene1520	4.849e-42	155.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1ISSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CSH2_k127_4727081_1	929713.NIASO_18860	9.866e-51	183.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,1ISJI@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CSH2_k127_4728002_0	1357272.AVEO02000111_gene3585	1.231e-11	74.0	COG4260@1|root,COG4260@2|Bacteria,1N14U@1224|Proteobacteria	1224|Proteobacteria	S	virion core protein, lumpy skin disease virus	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4728537_2	700598.Niako_6443	7.011e-91	308.0	COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,1IWXD@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CSH2_k127_4728537_1	925409.KI911562_gene420	4.736e-98	324.0	COG0745@1|root,COG0745@2|Bacteria,4NMAD@976|Bacteroidetes,1J08B@117747|Sphingobacteriia	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CSH2_k127_4728537_3	313606.M23134_02285	1.772e-25	111.0	2DNUQ@1|root,32Z94@2|Bacteria,4NVH0@976|Bacteroidetes,47QAG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
CSH2_k127_4728537_0	700598.Niako_6597	3.135e-122	397.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1IPZH@117747|Sphingobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CSH2_k127_4728537_4	313595.P700755_001238	9.389e-07	61.0	COG4249@1|root,COG4249@2|Bacteria,4NH9I@976|Bacteroidetes,1I151@117743|Flavobacteriia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
CSH2_k127_4729074_1	485918.Cpin_1987	6.651e-54	193.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1IS0X@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
CSH2_k127_4729074_0	1123248.KB893321_gene546	3.132e-111	367.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CSH2_k127_47372_0	445961.IW15_18175	1.459e-63	227.0	COG4413@1|root,COG4413@2|Bacteria,4NHK4@976|Bacteroidetes,1I1WG@117743|Flavobacteriia,3ZQ1B@59732|Chryseobacterium	976|Bacteroidetes	E	Urea transporter	-	-	-	ko:K08717	-	-	-	-	ko00000,ko02000	1.A.28.2	-	-	UT
CSH2_k127_47372_1	1123248.KB893322_gene627	5.707e-24	102.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1IX4W@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CSH2_k127_473967_0	1267211.KI669560_gene2276	7.278e-73	249.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CSH2_k127_473967_1	700598.Niako_3687	5.254e-53	192.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1IU9P@117747|Sphingobacteriia	976|Bacteroidetes	S	SMART PUR-alpha beta gamma DNA RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
CSH2_k127_473967_3	700598.Niako_4414	2.701e-36	143.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IYEG@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CSH2_k127_473967_2	925409.KI911562_gene2869	2.389e-46	169.0	COG2227@1|root,COG2227@2|Bacteria,4PKUR@976|Bacteroidetes,1J0TH@117747|Sphingobacteriia	976|Bacteroidetes	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
CSH2_k127_4740992_1	700598.Niako_5742	4.022e-12	68.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CSH2_k127_4740992_0	925409.KI911562_gene379	5.7e-67	237.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1IQCU@117747|Sphingobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CSH2_k127_4744042_0	1237149.C900_05169	4.038e-29	126.0	COG3548@1|root,COG3548@2|Bacteria,4NW8Z@976|Bacteroidetes,47V92@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
CSH2_k127_4751378_1	700598.Niako_6963	1.763e-100	330.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
CSH2_k127_4751378_2	1121887.AUDK01000004_gene292	3.195e-54	202.0	COG1917@1|root,COG1917@2|Bacteria,4NRZM@976|Bacteroidetes,1I5G8@117743|Flavobacteriia,2NV52@237|Flavobacterium	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4751378_0	700598.Niako_6974	2.77e-112	366.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1IPWN@117747|Sphingobacteriia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CSH2_k127_4751534_0	1313421.JHBV01000049_gene88	2.957e-46	169.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
CSH2_k127_4751534_1	313612.L8106_30745	1.986e-26	118.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
CSH2_k127_4753938_3	1123248.KB893326_gene1278	4.717e-07	55.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,1IU3T@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane chaperone Skp	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CSH2_k127_4753938_0	925409.KI911562_gene2126	3.554e-56	200.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1ISE3@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CSH2_k127_4753938_2	925409.KI911562_gene2171	1.307e-25	109.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1ITWJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CSH2_k127_4753938_1	1267211.KI669560_gene1564	5.112e-40	156.0	2FEUI@1|root,346TG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4755498_1	929556.Solca_4204	3.949e-34	139.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1IRJE@117747|Sphingobacteriia	976|Bacteroidetes	MU	TIGRFAM efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
CSH2_k127_4755498_0	1239962.C943_01002	1.976e-99	331.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CSH2_k127_4760117_0	1239962.C943_02333	7.932e-228	707.0	COG1274@1|root,COG1274@2|Bacteria,4NIPX@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CSH2_k127_4763583_1	643867.Ftrac_0116	1.136e-32	130.0	COG3654@1|root,COG3654@2|Bacteria,4P630@976|Bacteroidetes,47W8U@768503|Cytophagia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
CSH2_k127_4763583_0	1123248.KB893386_gene1824	2.652e-138	442.0	COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,1IPUE@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Helicase conserved C-terminal domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
CSH2_k127_4775600_0	1122605.KB893628_gene4485	1.429e-140	457.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1IP4Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CSH2_k127_4789807_0	929713.NIASO_00840	6.715e-155	499.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2373 Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
CSH2_k127_4790806_1	1347342.BN863_35150	6.205e-22	98.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CSH2_k127_4790806_0	1279009.ADICEAN_03693	6.1e-175	554.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,47JKM@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CSH2_k127_4791191_0	1267211.KI669560_gene1455	3.415e-275	849.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1IQIR@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CSH2_k127_4793949_3	700598.Niako_0469	2.167e-39	150.0	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1IQM7@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
CSH2_k127_4793949_2	1288963.ADIS_1418	2.589e-44	162.0	COG4104@1|root,COG4104@2|Bacteria,4NSCZ@976|Bacteroidetes,47RUU@768503|Cytophagia	976|Bacteroidetes	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
CSH2_k127_4793949_1	1296416.JACB01000029_gene4198	5.476e-65	224.0	COG3628@1|root,COG3628@2|Bacteria,4NSKN@976|Bacteroidetes,1I48Y@117743|Flavobacteriia,2YJZ4@290174|Aquimarina	976|Bacteroidetes	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
CSH2_k127_4793949_0	1296416.JACB01000029_gene4197	8.975e-66	237.0	COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1HYP7@117743|Flavobacteriia,2YIDG@290174|Aquimarina	976|Bacteroidetes	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CSH2_k127_4805783_1	925409.KI911562_gene2016	2.777e-13	70.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1IP6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CSH2_k127_4805783_0	700598.Niako_4325	5.046e-126	411.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1INVP@117747|Sphingobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CSH2_k127_4806841_1	485918.Cpin_1665	3.45e-192	612.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1IQXH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CSH2_k127_4806841_0	925409.KI911562_gene2578	1.131e-246	768.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1IQY7@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_4806841_2	700598.Niako_4537	8.046e-25	107.0	COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,1ITRS@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
CSH2_k127_4809460_1	1250006.JHZZ01000001_gene1660	4.419e-33	145.0	2EZ38@1|root,33S9G@2|Bacteria,4P0FQ@976|Bacteroidetes,1I8CU@117743|Flavobacteriia,3VWYX@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4809460_0	1250006.JHZZ01000001_gene1659	4.532e-196	630.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,1HYXG@117743|Flavobacteriia,3VX2H@52959|Polaribacter	976|Bacteroidetes	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_hydro_26,Glyco_hydro_2_C,Glyco_transf_21
CSH2_k127_4812491_0	1267211.KI669560_gene1029	2.774e-173	547.0	COG0366@1|root,COG0366@2|Bacteria,4NI8U@976|Bacteroidetes,1IUZK@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
CSH2_k127_4818292_1	1123277.KB893195_gene5705	3.05e-128	417.0	COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,47M1G@768503|Cytophagia	976|Bacteroidetes	E	alanine racemase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
CSH2_k127_4818292_0	471854.Dfer_0448	6.151e-208	649.0	COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,47JHR@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CSH2_k127_4821722_0	485913.Krac_2474	1.884e-130	424.0	COG3328@1|root,COG3328@2|Bacteria,2G6SX@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
CSH2_k127_483601_0	866536.Belba_3163	6.953e-56	213.0	COG2374@1|root,COG2374@2|Bacteria,4NHFV@976|Bacteroidetes,47M74@768503|Cytophagia	976|Bacteroidetes	M	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Exo_endo_phos
CSH2_k127_4836073_0	1123248.KB893381_gene1020	3.582e-138	451.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,1IQAZ@117747|Sphingobacteriia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CSH2_k127_4837159_1	1267211.KI669560_gene699	2.047e-53	192.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1IRJ2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
CSH2_k127_4837159_2	929713.NIASO_14580	4.201e-38	150.0	COG2105@1|root,COG2105@2|Bacteria,4NUSS@976|Bacteroidetes,1IZG0@117747|Sphingobacteriia	976|Bacteroidetes	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CSH2_k127_4837159_0	929713.NIASO_02330	1.253e-91	315.0	COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1IQZ9@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4837401_0	443144.GM21_1687	3.214e-152	492.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42NJI@68525|delta/epsilon subdivisions,2WJI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
CSH2_k127_4837401_1	1296416.JACB01000029_gene4206	1.882e-12	76.0	2DSUR@1|root,33HH4@2|Bacteria,4P5D2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4846595_0	700598.Niako_5048	1.695e-95	322.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IURB@117747|Sphingobacteriia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CSH2_k127_4846595_1	575615.HMPREF0670_01873	3.55e-05	46.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMQ9@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
CSH2_k127_4852545_0	1123248.KB893323_gene1605	8.108e-143	464.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1IV2A@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CSH2_k127_4852545_1	700598.Niako_4582	2.641e-105	347.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1IPT6@117747|Sphingobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CSH2_k127_4861311_0	700598.Niako_2221	1.475e-140	451.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IRC7@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CSH2_k127_4862976_0	925409.KI911562_gene2039	6.681e-290	908.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CSH2_k127_4862976_1	925409.KI911562_gene2345	5.424e-79	266.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CSH2_k127_4862976_2	1123248.KB893314_gene3477	5.054e-39	151.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,1IPQM@117747|Sphingobacteriia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CSH2_k127_4869411_0	1120966.AUBU01000005_gene3625	4.847e-181	570.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CSH2_k127_4894057_0	1121904.ARBP01000001_gene5632	3.106e-14	85.0	28MEF@1|root,2ZAS2@2|Bacteria,4NINI@976|Bacteroidetes,47S3F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4895278_1	925409.KI911562_gene2280	5.808e-32	130.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CSH2_k127_4897772_1	1267211.KI669560_gene2162	1.132e-81	273.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CSH2_k127_4897772_0	1123248.KB893386_gene1867	4.848e-220	694.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1IQK8@117747|Sphingobacteriia	976|Bacteroidetes	S	gliding motility-associated lipoprotein GldJ	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_4898405_6	1235802.C823_04178	4.131e-05	49.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
CSH2_k127_4898405_0	388413.ALPR1_16883	5.25e-75	261.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	PKD,Pro_isomerase
CSH2_k127_4898405_2	1267211.KI669560_gene716	6.332e-58	207.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IT1E@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CSH2_k127_4898405_4	1267211.KI669560_gene715	1.169e-41	159.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,1IS9P@117747|Sphingobacteriia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CSH2_k127_4898405_3	700598.Niako_5746	2.556e-46	179.0	COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,1IS07@117747|Sphingobacteriia	976|Bacteroidetes	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
CSH2_k127_4898405_5	925409.KI911562_gene452	2.846e-16	84.0	COG5652@1|root,COG5652@2|Bacteria,4NXUQ@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
CSH2_k127_4898405_1	1123248.KB893348_gene284	1.36e-71	246.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,1IY3D@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
CSH2_k127_4907720_1	1218108.KB908296_gene3126	9.526e-88	294.0	COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,1HWQ3@117743|Flavobacteriia	976|Bacteroidetes	M	Transferase	wcgN	-	2.7.8.36	ko:K15915	-	-	R10184	RC00002	ko00000,ko01000	-	-	-	Bac_transf
CSH2_k127_4907720_2	483216.BACEGG_02128	1.759e-54	197.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,2FNDD@200643|Bacteroidia,4ANIF@815|Bacteroidaceae	976|Bacteroidetes	S	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	neuD	-	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
CSH2_k127_4907720_0	883096.HMPREF9699_01727	3.354e-94	314.0	COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pglE	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CSH2_k127_4909532_2	1267211.KI669560_gene391	2.083e-15	79.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1ITJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4909532_1	700598.Niako_2074	2.381e-34	138.0	2DVQJ@1|root,32UZZ@2|Bacteria,4PGTB@976|Bacteroidetes,1IUA6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4909532_0	1267211.KI669560_gene32	4.314e-68	233.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1IRSG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CSH2_k127_491389_0	742767.HMPREF9456_02247	4.626e-175	558.0	COG0521@1|root,COG0521@2|Bacteria,4NG3I@976|Bacteroidetes,2FPRM@200643|Bacteroidia,22XYN@171551|Porphyromonadaceae	976|Bacteroidetes	H	Susd and RagB outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
CSH2_k127_491933_3	746697.Aeqsu_0222	8.59e-07	55.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1I18T@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_491933_1	925409.KI911562_gene2948	1.724e-132	428.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1IPCV@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CSH2_k127_491933_0	925409.KI911562_gene2947	2.038e-143	458.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1IQ5V@117747|Sphingobacteriia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CSH2_k127_491933_2	485918.Cpin_2032	6.311e-87	291.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CSH2_k127_491989_1	1237149.C900_01451	9.972e-18	85.0	COG1943@1|root,COG1943@2|Bacteria,4NJZI@976|Bacteroidetes,47PW0@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CSH2_k127_491989_0	925409.KI911562_gene994	2.226e-160	514.0	COG1835@1|root,COG1835@2|Bacteria,4NEW1@976|Bacteroidetes,1IPYD@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CSH2_k127_4923767_0	1267211.KI669560_gene659	3.124e-37	141.0	COG0431@1|root,COG0431@2|Bacteria,4NNY7@976|Bacteroidetes	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CSH2_k127_4923767_2	743722.Sph21_3442	1.694e-30	126.0	COG1765@1|root,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1IW22@117747|Sphingobacteriia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
CSH2_k127_4923767_1	504472.Slin_1870	1.085e-34	135.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47P9R@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CSH2_k127_4927625_1	1122605.KB893649_gene3840	1.243e-79	266.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1IRUT@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CSH2_k127_4927625_0	1123248.KB893381_gene1097	1.436e-123	398.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1IPE4@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CSH2_k127_4927625_2	1122605.KB893649_gene3838	1.76e-78	267.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1IS1J@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CSH2_k127_4927625_4	929713.NIASO_11230	4.139e-51	183.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1ISEQ@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CSH2_k127_4927625_3	926549.KI421517_gene1784	5.31e-63	222.0	COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,47R7F@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CSH2_k127_4929323_0	700598.Niako_6904	3.44e-58	206.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1ISAN@117747|Sphingobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CSH2_k127_4929323_1	700598.Niako_6905	2.182e-23	102.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1ITDM@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CSH2_k127_4954758_0	925409.KI911562_gene2965	1.149e-109	366.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1IQ6E@117747|Sphingobacteriia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CSH2_k127_4954758_1	925409.KI911562_gene2709	2.541e-34	132.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IWFS@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_4957771_0	1123248.KB893348_gene214	5.701e-99	324.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CSH2_k127_4957771_1	1123248.KB893348_gene215	3.325e-70	241.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CSH2_k127_4957771_4	700598.Niako_6596	8.687e-17	88.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CSH2_k127_4957771_3	700598.Niako_6664	6.925e-52	189.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes,1J0EF@117747|Sphingobacteriia	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CSH2_k127_4957771_2	929562.Emtol_0758	1.303e-60	216.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CSH2_k127_4964634_0	1185876.BN8_01431	1.869e-112	370.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MF5@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,HTH_18,MacB_PCD
CSH2_k127_4964634_1	1123277.KB893172_gene535	9.283e-110	376.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CSH2_k127_4965020_1	1123248.KB893316_gene4553	4.907e-19	90.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1INTS@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
CSH2_k127_4965020_0	1089547.KB913013_gene2684	5.712e-93	310.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,47K9T@768503|Cytophagia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CSH2_k127_4967556_0	1239962.C943_03737	1.034e-113	372.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_4975720_0	925409.KI911562_gene2974	9.746e-117	388.0	COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,1IQNH@117747|Sphingobacteriia	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CSH2_k127_4975720_1	925409.KI911562_gene867	7.361e-87	294.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CSH2_k127_4978976_0	925409.KI911562_gene640	3.144e-245	762.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
CSH2_k127_4979629_0	1296416.JACB01000029_gene4196	7.221e-179	574.0	COG3422@1|root,COG3422@2|Bacteria,4NHE4@976|Bacteroidetes,1I0UZ@117743|Flavobacteriia,2YHEU@290174|Aquimarina	976|Bacteroidetes	S	double-strand break repair	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4979629_1	1122176.KB903539_gene1428	3.223e-20	91.0	COG3291@1|root,COG3291@2|Bacteria,4NI5F@976|Bacteroidetes,1IRIG@117747|Sphingobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,PKD
CSH2_k127_4979902_0	1123248.KB893348_gene258	1.318e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_4979902_1	700598.Niako_6665	4.474e-33	136.0	28NPZ@1|root,2ZBPQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CSH2_k127_4987508_0	1089547.KB913013_gene4261	1.837e-72	246.0	COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,47JWC@768503|Cytophagia	976|Bacteroidetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CSH2_k127_4987508_1	1150600.ADIARSV_3081	2.083e-63	224.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,1IPEM@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0826 Collagenase and related	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CSH2_k127_498782_1	1123248.KB893337_gene2550	5.291e-55	195.0	COG0633@1|root,COG0633@2|Bacteria,4NTVJ@976|Bacteroidetes,1ITJK@117747|Sphingobacteriia	976|Bacteroidetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CSH2_k127_498782_2	1267211.KI669560_gene1429	1.978e-39	148.0	COG2975@1|root,COG2975@2|Bacteria,4NSUG@976|Bacteroidetes,1ITCB@117747|Sphingobacteriia	976|Bacteroidetes	S	FeS assembly protein IscX	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
CSH2_k127_498782_0	485918.Cpin_1957	2.938e-63	221.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1ISY0@117747|Sphingobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
CSH2_k127_498782_3	925409.KI911562_gene2631	2.856e-05	46.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1IYC2@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CSH2_k127_4988101_1	1267211.KI669560_gene998	9.212e-05	50.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1IV3Y@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
CSH2_k127_4988101_0	1123248.KB893315_gene3012	4.941e-133	432.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CSH2_k127_499782_0	886379.AEWI01000040_gene2774	2.651e-05	53.0	COG2353@1|root,COG3210@1|root,COG5492@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,4PNR0@976|Bacteroidetes,2FNS2@200643|Bacteroidia,3XJMD@558415|Marinilabiliaceae	976|Bacteroidetes	NU	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Laminin_G_3
CSH2_k127_4999303_0	925409.KI911562_gene878	1.93e-322	998.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
CSH2_k127_5008525_1	1123278.KB893576_gene1352	4.199e-25	105.0	COG4221@1|root,COG4221@2|Bacteria,4NHEQ@976|Bacteroidetes,47M62@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_5008525_2	925409.KI911562_gene1314	3.639e-23	106.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
CSH2_k127_5008525_0	1267211.KI669560_gene666	2.823e-32	129.0	COG2267@1|root,COG2267@2|Bacteria,4NK38@976|Bacteroidetes,1IT00@117747|Sphingobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
CSH2_k127_5017549_0	700598.Niako_6693	6.426e-117	385.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1IP8I@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
CSH2_k127_5017549_1	700598.Niako_1336	6.427e-107	353.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,1IVK3@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CSH2_k127_5018791_0	1267211.KI669560_gene1186	9.388e-210	660.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_5018791_1	1267211.KI669560_gene1187	1.282e-26	110.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CSH2_k127_5019068_1	1121875.KB907549_gene1756	1.77e-35	139.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CSH2_k127_5019068_0	573413.Spirs_1272	4.982e-42	164.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CSH2_k127_5020273_0	1123248.KB893332_gene2263	1.464e-219	696.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_5020273_1	1121859.KB890738_gene2929	2.048e-45	173.0	COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,47KAD@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_5021650_1	485918.Cpin_2010	2.979e-62	223.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1IUSP@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CSH2_k127_5021650_0	1358423.N180_03265	1.487e-116	382.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1IV9H@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CSH2_k127_5022225_2	362418.IW19_00120	1.112e-73	267.0	COG2374@1|root,COG2374@2|Bacteria,4PKDU@976|Bacteroidetes,1IJ8H@117743|Flavobacteriia,2NV5C@237|Flavobacterium	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,LTD
CSH2_k127_5022225_4	926549.KI421517_gene29	2.462e-22	111.0	COG3391@1|root,COG3391@2|Bacteria,4NSPG@976|Bacteroidetes,47V9V@768503|Cytophagia	976|Bacteroidetes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5022225_0	1123248.KB893385_gene4884	4.112e-281	876.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1IP5W@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock protein Hsp90	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
CSH2_k127_5022225_3	485918.Cpin_1724	4.971e-53	194.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_4
CSH2_k127_5022225_1	700598.Niako_5115	2.76e-98	325.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CSH2_k127_5035604_2	1123248.KB893381_gene1074	3.163e-16	84.0	COG1555@1|root,COG1555@2|Bacteria,4NUGB@976|Bacteroidetes,1J0F4@117747|Sphingobacteriia	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5035604_0	700598.Niako_0168	4.594e-129	421.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CSH2_k127_5035604_1	700598.Niako_0167	7.142e-47	170.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CSH2_k127_5041658_1	1122605.KB893637_gene3103	6.08e-20	91.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,1IRY7@117747|Sphingobacteriia	976|Bacteroidetes	M	Nlp p60 protein	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
CSH2_k127_5041658_0	700598.Niako_1029	2.938e-186	590.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IWD6@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_5042522_1	1270196.JCKI01000001_gene4137	6.205e-67	241.0	COG3228@1|root,COG3228@2|Bacteria,4NGM9@976|Bacteroidetes,1IRGU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
CSH2_k127_5042522_3	929562.Emtol_1414	4.74e-16	87.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_3,Response_reg
CSH2_k127_5042522_0	925409.KI911562_gene249	5.878e-299	934.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IUW9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CSH2_k127_5042522_2	485918.Cpin_1330	7.297e-48	172.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1IQ54@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CSH2_k127_5052879_1	1123248.KB893317_gene4406	9.484e-58	206.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CSH2_k127_5052879_0	485918.Cpin_6574	1.507e-99	331.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CSH2_k127_505722_4	1123277.KB893203_gene6259	1.865e-12	70.0	COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,47N41@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M20/M25/M40	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CSH2_k127_505722_0	1123277.KB893176_gene3732	1.518e-139	458.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CSH2_k127_505722_2	1123277.KB893176_gene3731	3.006e-26	124.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CSH2_k127_505722_3	504472.Slin_3815	8.629e-17	85.0	COG4319@1|root,COG4319@2|Bacteria,4NT0G@976|Bacteroidetes,47T3M@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
CSH2_k127_505722_1	1123057.P872_07650	2.411e-57	201.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,47JFN@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_5057550_2	929556.Solca_0459	8.309e-39	147.0	COG0662@1|root,COG0662@2|Bacteria,4NTZN@976|Bacteroidetes,1IYU4@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CSH2_k127_5057550_0	760192.Halhy_1263	7.594e-204	649.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CSH2_k127_5057550_1	1123278.KB893576_gene1350	1.186e-49	183.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,47PZ9@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
CSH2_k127_5061827_0	925409.KI911562_gene1048	3.207e-162	512.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CSH2_k127_5061827_1	1267211.KI669560_gene624	4.198e-55	195.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1IR44@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CSH2_k127_5064729_0	700598.Niako_4480	9.263e-19	99.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_5071252_0	929556.Solca_2779	6.189e-50	179.0	COG1274@1|root,COG1274@2|Bacteria,4NIPX@976|Bacteroidetes,1IUUX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CSH2_k127_5071252_2	1267211.KI669560_gene853	8.079e-19	87.0	COG1476@1|root,COG1476@2|Bacteria,4NWX1@976|Bacteroidetes,1IZC8@117747|Sphingobacteriia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CSH2_k127_5071252_1	1123248.KB893331_gene3769	1.214e-43	162.0	2DNMN@1|root,32Y54@2|Bacteria,4NW3V@976|Bacteroidetes,1IYIN@117747|Sphingobacteriia	976|Bacteroidetes	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
CSH2_k127_5072345_1	925409.KI911562_gene914	8.976e-20	92.0	COG4654@1|root,COG4654@2|Bacteria,4NSJC@976|Bacteroidetes,1ITX4@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
CSH2_k127_5072345_0	1123248.KB893319_gene3990	9.331e-165	520.0	COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1IQDJ@117747|Sphingobacteriia	976|Bacteroidetes	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CSH2_k127_507423_0	1123248.KB893318_gene4172	5.712e-227	709.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CSH2_k127_507423_1	925409.KI911562_gene2716	2.461e-15	76.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1IP50@117747|Sphingobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CSH2_k127_507737_0	485918.Cpin_7185	3.851e-73	249.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1ITKI@117747|Sphingobacteriia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CSH2_k127_507737_1	761193.Runsl_4827	2.141e-25	113.0	28HUE@1|root,2Z815@2|Bacteria,4NHK5@976|Bacteroidetes,47P5G@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CSH2_k127_508281_1	1123248.KB893314_gene3600	2.664e-37	142.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CSH2_k127_508281_0	1120968.AUBX01000015_gene3687	5.824e-79	272.0	COG0605@1|root,COG0605@2|Bacteria,4NK61@976|Bacteroidetes,47N71@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CSH2_k127_5083446_1	700598.Niako_5724	1.484e-97	321.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CSH2_k127_5083446_0	1123248.KB893385_gene4861	2.583e-148	475.0	COG0408@1|root,COG0408@2|Bacteria,4NFZS@976|Bacteroidetes,1IQE1@117747|Sphingobacteriia	976|Bacteroidetes	H	coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CSH2_k127_5083446_2	1123248.KB893385_gene4862	8.053e-31	122.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1INQH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CSH2_k127_5089740_0	1149133.ppKF707_1554	1.209e-155	501.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1YES8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CSH2_k127_5096095_0	700598.Niako_0113	3.9e-170	540.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1IR3G@117747|Sphingobacteriia	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CSH2_k127_5103762_1	925409.KI911562_gene2159	2.59e-52	197.0	2F5NW@1|root,33Y7T@2|Bacteria,4P34Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5103762_0	1034807.FBFL15_3059	1.418e-63	226.0	COG0697@1|root,COG0697@2|Bacteria,4NK8U@976|Bacteroidetes,1I01E@117743|Flavobacteriia,2NV5M@237|Flavobacterium	976|Bacteroidetes	EG	drug metabolite-transporting permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_5118949_0	700598.Niako_4487	2.965e-110	370.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,1J0IU@117747|Sphingobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CSH2_k127_5118949_1	1122176.KB903551_gene4227	1.261e-19	89.0	COG1225@1|root,COG1225@2|Bacteria,4NNHI@976|Bacteroidetes,1ISKK@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CSH2_k127_5123806_0	1123248.KB893348_gene232	5.858e-103	340.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_5123806_1	929713.NIASO_05035	1.059e-38	146.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1IVY0@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CSH2_k127_5124092_1	991.IW20_04785	5.719e-170	549.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,1HZX1@117743|Flavobacteriia,2NTKA@237|Flavobacterium	976|Bacteroidetes	E	peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CSH2_k127_5124092_0	1086011.HJ01_03293	4.359e-273	852.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia,2NTDC@237|Flavobacterium	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
CSH2_k127_5124092_2	1239962.C943_00111	1.095e-100	342.0	COG3356@1|root,COG3356@2|Bacteria,4NHGJ@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5124092_3	1233950.IW22_22215	3.831e-73	253.0	arCOG07533@1|root,2ZF5I@2|Bacteria,4NMWZ@976|Bacteroidetes,1I1RR@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
CSH2_k127_5124092_4	1233950.IW22_22210	1.208e-31	129.0	arCOG06733@1|root,313GU@2|Bacteria,4NQIM@976|Bacteroidetes,1I3KE@117743|Flavobacteriia,3ZTM4@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5127889_0	700598.Niako_4730	2.889e-119	400.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IPHQ@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CSH2_k127_5127889_1	700598.Niako_4730	4.343e-17	87.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1IPHQ@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CSH2_k127_5134119_1	1123248.KB893314_gene3699	1.645e-36	141.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5134119_0	1086011.HJ01_02925	1.542e-83	288.0	COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia,2NSRP@237|Flavobacterium	976|Bacteroidetes	E	aminotransferase, class I	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_5135407_3	929556.Solca_0885	1.922e-11	65.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1ITRK@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CSH2_k127_5135407_1	1267211.KI669560_gene1759	3.573e-58	205.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1IT04@117747|Sphingobacteriia	976|Bacteroidetes	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
CSH2_k127_5135407_0	1123248.KB893321_gene528	5.425e-70	240.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1ISUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CSH2_k127_5135407_2	485918.Cpin_5487	1.232e-21	94.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CSH2_k127_5136391_2	504472.Slin_2317	3.005e-45	167.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,47MUJ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CSH2_k127_5136391_0	925409.KI911562_gene2271	2.566e-72	247.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1IRWB@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
CSH2_k127_5136391_1	1267211.KI669560_gene1752	7.94e-66	229.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
CSH2_k127_5137685_0	700598.Niako_7219	3.798e-126	410.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQWT@117747|Sphingobacteriia	976|Bacteroidetes	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CSH2_k127_5137685_1	700598.Niako_7218	1.451e-42	159.0	COG0713@1|root,COG0713@2|Bacteria,4NSR8@976|Bacteroidetes,1ITB0@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CSH2_k127_5140949_1	1267211.KI669560_gene2650	3.543e-104	344.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IV4C@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_5140949_6	1121931.AUHG01000010_gene554	1.591e-32	137.0	28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes,1I0C7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5140949_3	700598.Niako_0183	6.12e-82	276.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CSH2_k127_5140949_5	485918.Cpin_1535	4.992e-78	265.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1IP9T@117747|Sphingobacteriia	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CSH2_k127_5140949_2	925409.KI911562_gene73	8.016e-87	293.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IST6@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CSH2_k127_5140949_4	925409.KI911562_gene2993	6.639e-79	278.0	COG0683@1|root,COG0683@2|Bacteria,4PMPE@976|Bacteroidetes,1ISIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
CSH2_k127_5140949_0	1123248.KB893319_gene4078	1.288e-315	972.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CSH2_k127_5142695_0	1239962.C943_04519	1.169e-131	428.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,47KU0@768503|Cytophagia	976|Bacteroidetes	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CSH2_k127_514600_1	1122621.ATZA01000007_gene787	4.771e-40	150.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_514600_0	1122621.ATZA01000007_gene786	2.182e-110	365.0	COG3193@1|root,COG3193@2|Bacteria,4PPN1@976|Bacteroidetes	976|Bacteroidetes	S	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
CSH2_k127_5147254_0	700598.Niako_0318	7.175e-143	460.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1INQY@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CSH2_k127_5147254_1	925409.KI911562_gene1921	1.773e-40	150.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1J0P2@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
CSH2_k127_5149311_1	1122222.AXWR01000052_gene66	1.273e-05	54.0	2ENQZ@1|root,33GC6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5149311_0	1121957.ATVL01000011_gene3664	6.869e-42	162.0	COG2935@1|root,COG2935@2|Bacteria,4NGKN@976|Bacteroidetes,47PCC@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the R-transferase family	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CSH2_k127_5149549_1	1150600.ADIARSV_1493	3.236e-07	58.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5149549_0	925409.KI911562_gene1471	9.968e-80	277.0	2BV6Z@1|root,32QKE@2|Bacteria,4PCAH@976|Bacteroidetes,1IZE7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5150131_0	925409.KI911562_gene2410	1.298e-230	723.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1IPGD@117747|Sphingobacteriia	976|Bacteroidetes	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
CSH2_k127_5154742_1	700598.Niako_4507	5.639e-82	274.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
CSH2_k127_5154742_0	925409.KI911562_gene2794	4.235e-118	390.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1IQ2Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CSH2_k127_5154742_2	700598.Niako_4504	4.327e-62	218.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1IQJK@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CSH2_k127_5156477_1	760192.Halhy_2531	2.541e-158	510.0	COG0531@1|root,COG0531@2|Bacteria,4NICM@976|Bacteroidetes,1IQNC@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CSH2_k127_5156477_2	714943.Mucpa_6418	3.579e-70	240.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,1ISSF@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CSH2_k127_5156477_0	925409.KI911562_gene1145	3.65e-174	553.0	COG0626@1|root,COG0626@2|Bacteria,4NH38@976|Bacteroidetes,1IUQW@117747|Sphingobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
CSH2_k127_5156477_3	1122605.KB893637_gene3292	8.655e-29	119.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IP2E@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CSH2_k127_5157305_0	760192.Halhy_4420	4.848e-170	541.0	COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CSH2_k127_5157305_1	1123057.P872_07650	1.105e-15	79.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,47JFN@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_5172884_0	1123248.KB893348_gene174	2.064e-93	317.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1INT0@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
CSH2_k127_5174192_0	925409.KI911562_gene1107	3.047e-224	703.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
CSH2_k127_5175081_0	1123248.KB893348_gene361	3.957e-198	636.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
CSH2_k127_5175209_2	1358423.N180_16895	3.737e-05	50.0	COG3528@1|root,COG3528@2|Bacteria,4NN7J@976|Bacteroidetes,1IS3K@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
CSH2_k127_5175209_0	925409.KI911562_gene827	3.621e-41	156.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1ITI6@117747|Sphingobacteriia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CSH2_k127_5175209_1	700598.Niako_6359	1.724e-36	141.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CSH2_k127_5175583_3	925409.KI911562_gene2065	2.288e-15	78.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CSH2_k127_5175583_1	1123248.KB893326_gene1478	2.547e-27	111.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1IU0H@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CSH2_k127_5175583_0	700598.Niako_4343	5.314e-81	274.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1ISWG@117747|Sphingobacteriia	976|Bacteroidetes	S	acr, cog1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
CSH2_k127_5175583_2	1453500.AT05_07595	7.91e-19	89.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CSH2_k127_5175664_2	1041139.KB902624_gene5808	1.377e-46	172.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,4BC1H@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CSH2_k127_5175664_0	1341181.FLJC2902T_04270	1.264e-128	420.0	COG0387@1|root,COG0387@2|Bacteria,4P224@976|Bacteroidetes	976|Bacteroidetes	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
CSH2_k127_5175664_1	1239962.C943_01293	1.033e-59	214.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CSH2_k127_5175664_4	1239962.C943_01292	8.31e-40	155.0	2E3FB@1|root,32YE4@2|Bacteria,4P77I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5175664_3	506534.Rhein_1504	4.314e-45	167.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria,1WYVA@135613|Chromatiales	135613|Chromatiales	M	Asp/Glu/Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
CSH2_k127_5184003_0	1121957.ATVL01000010_gene133	3.236e-240	751.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,47KUW@768503|Cytophagia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
CSH2_k127_5188939_0	1122605.KB893646_gene100	1.507e-65	228.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1INKY@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CSH2_k127_5189111_1	929713.NIASO_02330	2.702e-23	107.0	COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1IQZ9@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5189111_0	929713.NIASO_14800	2.435e-112	367.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1IQ9A@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
CSH2_k127_5189111_2	1123248.KB893319_gene4068	0.0001879	47.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5211423_0	925409.KI911562_gene2149	3.769e-72	249.0	COG2910@1|root,COG2910@2|Bacteria,4PP94@976|Bacteroidetes,1IYBJ@117747|Sphingobacteriia	976|Bacteroidetes	S	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CSH2_k127_5211423_1	925409.KI911562_gene2150	2.824e-36	140.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1ITHB@117747|Sphingobacteriia	976|Bacteroidetes	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
CSH2_k127_5211423_2	700598.Niako_4423	3.757e-26	109.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_5215640_0	926556.Echvi_1860	4.12e-192	623.0	COG2197@1|root,COG3292@1|root,COG2197@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,47M6U@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HTH_18,HisKA_2,Reg_prop,Response_reg,SpoIIE,Y_Y_Y
CSH2_k127_5215640_1	925409.KI911562_gene2486	1.987e-109	358.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1IQ5P@117747|Sphingobacteriia	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CSH2_k127_5216389_0	925409.KI911562_gene1176	1.225e-92	318.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CSH2_k127_5216389_1	700598.Niako_5523	4.907e-43	160.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CSH2_k127_5217466_0	700598.Niako_6349	1.887e-200	629.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes	976|Bacteroidetes	C	alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
CSH2_k127_5220821_0	1239962.C943_01002	1.246e-206	655.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CSH2_k127_5225358_0	1123278.KB893397_gene5346	4.991e-84	294.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47KW1@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
CSH2_k127_522672_0	1267211.KI669560_gene236	4.269e-146	470.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
CSH2_k127_522783_0	1122605.KB893630_gene4049	4.952e-222	698.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1IQVW@117747|Sphingobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_522783_1	485918.Cpin_1555	9.87e-06	48.0	2CVJ7@1|root,32SXQ@2|Bacteria,4NTD0@976|Bacteroidetes,1IZC0@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4265)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4265
CSH2_k127_5230881_1	1123248.KB893314_gene3602	3.477e-12	74.0	2CFIN@1|root,302AR@2|Bacteria,4PJAS@976|Bacteroidetes,1IZWV@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5230881_0	1122605.KB893646_gene14	8.173e-41	151.0	COG3408@1|root,COG3408@2|Bacteria,4PKJG@976|Bacteroidetes,1IQX7@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
CSH2_k127_5241117_1	700598.Niako_6698	1.148e-19	92.0	2EHHG@1|root,33B9E@2|Bacteria,4NXY9@976|Bacteroidetes,1IUFY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5241117_0	1131812.JQMS01000001_gene941	4.432e-54	198.0	2CJWE@1|root,30Y1E@2|Bacteria,4NNQQ@976|Bacteroidetes,1I40A@117743|Flavobacteriia,2NYX7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5255085_1	1121895.Q765_08825	1.311e-16	93.0	COG1404@1|root,COG1572@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1I0G4@117743|Flavobacteriia,2NT7Y@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,He_PIG,fn3
CSH2_k127_5255085_0	313606.M23134_06773	1.994e-60	228.0	COG2911@1|root,COG3291@1|root,COG4447@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4NI13@976|Bacteroidetes,47NV6@768503|Cytophagia	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_5261938_0	1267211.KI669560_gene510	3.274e-266	833.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1IPE8@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
CSH2_k127_5265545_3	1267211.KI669560_gene78	1.579e-91	303.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1IQUC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CSH2_k127_5265545_1	925409.KI911562_gene428	6.227e-138	446.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1IPHE@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CSH2_k127_5265545_5	1123248.KB893386_gene1821	7.187e-31	125.0	COG0662@1|root,COG0662@2|Bacteria,4NVRF@976|Bacteroidetes,1ITU1@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CSH2_k127_5265545_0	700598.Niako_5689	9.961e-215	671.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CSH2_k127_5265545_2	700598.Niako_5688	3.849e-107	352.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IR6P@117747|Sphingobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_5265545_4	313603.FB2170_11691	3.386e-38	147.0	2C82G@1|root,32RK9@2|Bacteria,4NSXV@976|Bacteroidetes,1I466@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CSH2_k127_5265545_6	700598.Niako_4625	1.088e-27	117.0	COG2114@1|root,COG2207@1|root,COG2114@2|Bacteria,COG2207@2|Bacteria,4NFVC@976|Bacteroidetes,1IXZX@117747|Sphingobacteriia	976|Bacteroidetes	K	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242,HTH_18
CSH2_k127_5266840_1	925409.KI911562_gene3000	8.084e-159	503.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,1INTU@117747|Sphingobacteriia	976|Bacteroidetes	J	PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CSH2_k127_5266840_2	1123277.KB893178_gene2675	1.796e-44	166.0	293T3@1|root,2ZR8H@2|Bacteria,4NMK3@976|Bacteroidetes,47PZ7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
CSH2_k127_5266840_3	1122621.ATZA01000015_gene3678	4.329e-21	96.0	2EGWS@1|root,33ANX@2|Bacteria,4NZCT@976|Bacteroidetes,1IUQG@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5266840_4	1296415.JACC01000006_gene1446	3.84e-07	58.0	2DN1K@1|root,32UYW@2|Bacteria,4NSZV@976|Bacteroidetes,1I4R9@117743|Flavobacteriia,2YKXB@290174|Aquimarina	976|Bacteroidetes	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
CSH2_k127_5266840_0	1434325.AZQN01000002_gene1161	1.068e-216	678.0	COG0523@1|root,COG0523@2|Bacteria,4NENH@976|Bacteroidetes,47MHA@768503|Cytophagia	976|Bacteroidetes	S	Cobalamin synthesis protein cobW C-terminal domain	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
CSH2_k127_5267956_0	700598.Niako_5481	2.844e-89	303.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CSH2_k127_5269379_0	395493.BegalDRAFT_1353	2.505e-35	151.0	COG1680@1|root,COG1680@2|Bacteria,1PF8A@1224|Proteobacteria,1SWQW@1236|Gammaproteobacteria,462UZ@72273|Thiotrichales	72273|Thiotrichales	V	PFAM beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CSH2_k127_5269379_1	760192.Halhy_2410	4.993e-16	85.0	2E8IG@1|root,332WH@2|Bacteria,4NWJT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5274521_1	485918.Cpin_0826	4.724e-85	293.0	COG0577@1|root,COG0577@2|Bacteria,4NGDV@976|Bacteroidetes,1IXUG@117747|Sphingobacteriia	976|Bacteroidetes	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5274521_0	1122605.KB893646_gene22	2.464e-160	508.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1IR5V@117747|Sphingobacteriia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CSH2_k127_5275173_2	1267211.KI669560_gene2401	1.143e-16	79.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1IP3M@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CSH2_k127_5275173_0	929713.NIASO_18530	7.497e-159	508.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1IPZM@117747|Sphingobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CSH2_k127_5279745_1	925409.KI911562_gene2054	1.582e-20	93.0	COG1349@1|root,COG1349@2|Bacteria,4NE7U@976|Bacteroidetes,1IPYC@117747|Sphingobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, deoR family	glcR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
CSH2_k127_5279745_0	929556.Solca_1038	2.816e-112	374.0	COG4206@1|root,COG4774@1|root,COG4206@2|Bacteria,COG4774@2|Bacteria,4NZWU@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_5288803_1	925409.KI911562_gene1099	7.976e-37	141.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CSH2_k127_5288803_2	984262.SGRA_2566	1.536e-07	53.0	2DTGS@1|root,33K9M@2|Bacteria,4NYMF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5288803_0	1123248.KB893386_gene1838	4.023e-60	218.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CSH2_k127_5294857_1	1123248.KB893326_gene1426	1.117e-32	133.0	COG0860@1|root,COG0860@2|Bacteria,4P1J0@976|Bacteroidetes,1IVQV@117747|Sphingobacteriia	976|Bacteroidetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CSH2_k127_5294857_0	1123248.KB893326_gene1427	3.37e-100	337.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_531170_0	1122179.KB890431_gene4240	1.447e-31	140.0	COG0666@1|root,COG0666@2|Bacteria,4NM6P@976|Bacteroidetes	976|Bacteroidetes	E	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
CSH2_k127_5313468_2	925409.KI911562_gene1200	1.14e-25	108.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1ITDM@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CSH2_k127_5313468_0	700598.Niako_1035	8.951e-48	175.0	COG2905@1|root,COG2905@2|Bacteria,4NTKX@976|Bacteroidetes,1J0SE@117747|Sphingobacteriia	976|Bacteroidetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CSH2_k127_5313468_1	700598.Niako_6909	2.518e-39	151.0	COG1629@1|root,COG4771@2|Bacteria,4PKRZ@976|Bacteroidetes,1J0Q2@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_5316352_0	1267211.KI669560_gene1027	1.667e-130	423.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CSH2_k127_5316352_1	700598.Niako_6698	1.083e-05	51.0	2EHHG@1|root,33B9E@2|Bacteria,4NXY9@976|Bacteroidetes,1IUFY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5317716_0	1267211.KI669560_gene2035	2.052e-72	252.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1ISRU@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_5317716_2	359.CN09_28410	1.194e-05	57.0	COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,2U84N@28211|Alphaproteobacteria,4BENY@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	pecS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CSH2_k127_5317716_1	1107311.Q767_05060	2.812e-64	224.0	COG1670@1|root,COG1670@2|Bacteria,4NMB7@976|Bacteroidetes,1I271@117743|Flavobacteriia,2P04V@237|Flavobacterium	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CSH2_k127_5322647_0	761193.Runsl_3068	5.388e-204	645.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_5322647_1	1433126.BN938_1211	1.333e-08	56.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,2FS50@200643|Bacteroidia,22V9H@171550|Rikenellaceae	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CSH2_k127_5325576_1	700598.Niako_2152	1.516e-41	156.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IWBC@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CSH2_k127_5325576_0	1267211.KI669560_gene1438	3.919e-144	462.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
CSH2_k127_5325713_1	929556.Solca_3217	5.493e-17	85.0	28JKB@1|root,2Z9D6@2|Bacteria,4NJC1@976|Bacteroidetes,1IRBG@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5325713_0	925409.KI911562_gene417	7.757e-202	635.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CSH2_k127_5325763_0	700598.Niako_7335	1.471e-168	537.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1IPA1@117747|Sphingobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CSH2_k127_5326341_3	1341181.FLJC2902T_28550	1.497e-32	138.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5326341_4	1341181.FLJC2902T_28550	2.171e-11	68.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5326341_0	886377.Murru_1501	7.156e-127	413.0	COG1506@1|root,COG1506@2|Bacteria,4NKM9@976|Bacteroidetes,1I0MY@117743|Flavobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CSH2_k127_5326341_1	1089547.KB913013_gene252	2.86e-118	388.0	COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,47JGG@768503|Cytophagia	976|Bacteroidetes	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CSH2_k127_5326341_2	649349.Lbys_3108	4.952e-77	262.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_5326680_1	1123277.KB893172_gene535	3.929e-32	131.0	COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CSH2_k127_5326680_0	761193.Runsl_1884	1.195e-33	138.0	COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes,47MIA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CSH2_k127_5337600_0	1121373.KB903632_gene586	3.115e-27	119.0	COG1835@1|root,COG1835@2|Bacteria,4NPI2@976|Bacteroidetes,47NBE@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CSH2_k127_5342994_0	925409.KI911562_gene2779	1.201e-73	252.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1INX0@117747|Sphingobacteriia	976|Bacteroidetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
CSH2_k127_5342994_1	1122605.KB893645_gene987	3.849e-58	204.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1ISQ1@117747|Sphingobacteriia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CSH2_k127_5343553_1	1150600.ADIARSV_1361	2.251e-88	302.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1IUMA@117747|Sphingobacteriia	976|Bacteroidetes	G	hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5343553_0	906888.JCM19314_1533	2.928e-168	551.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia,3HKV5@363408|Nonlabens	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
CSH2_k127_5343553_2	1150600.ADIARSV_1363	2.062e-45	165.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,1IQB0@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_5353464_0	391596.PBAL39_07655	1.07e-143	463.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IRKC@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_5353787_0	929713.NIASO_00855	2.359e-89	297.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
CSH2_k127_5353787_1	983544.Lacal_2823	2.071e-19	94.0	2C6Z5@1|root,32RI1@2|Bacteria,4NRFR@976|Bacteroidetes,1I3D7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5354707_1	929556.Solca_1743	6.659e-102	336.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1IPKV@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CSH2_k127_5354707_0	1267211.KI669560_gene2086	2.238e-196	620.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,1INQM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CSH2_k127_5354707_2	585543.HMPREF0969_00632	2.121e-22	100.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia,4AN2X@815|Bacteroidaceae	976|Bacteroidetes	P	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
CSH2_k127_5360483_0	700598.Niako_7059	9.173e-73	251.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes	976|Bacteroidetes	P	Phosphate ABC transporter substrate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CSH2_k127_5362205_1	883096.HMPREF9699_00432	1.534e-09	67.0	COG2244@1|root,COG2244@2|Bacteria,4NRKF@976|Bacteroidetes,1I3V4@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CSH2_k127_5362205_0	1123248.KB893337_gene2512	2.442e-25	107.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CSH2_k127_5371379_0	1168034.FH5T_13870	8.588e-142	453.0	COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes,2FN6V@200643|Bacteroidia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase	ce	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
CSH2_k127_5371379_1	760192.Halhy_5309	1.779e-58	208.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CSH2_k127_537221_0	1267211.KI669560_gene2552	1.837e-142	454.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_537576_3	1035193.HMPREF9073_02674	0.0001228	47.0	COG1629@1|root,COG4771@2|Bacteria,4NEI4@976|Bacteroidetes,1IFZ4@117743|Flavobacteriia,1ERIW@1016|Capnocytophaga	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
CSH2_k127_537576_0	1267211.KI669560_gene2733	1.078e-105	351.0	COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CSH2_k127_537576_1	760192.Halhy_0613	1.018e-68	241.0	2E0SZ@1|root,32WAT@2|Bacteria,4NIDB@976|Bacteroidetes,1IXSM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CSH2_k127_537576_2	592029.DDD_3108	1.97e-24	106.0	COG0500@1|root,COG0500@2|Bacteria,4PM90@976|Bacteroidetes,1IJN7@117743|Flavobacteriia	976|Bacteroidetes	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CSH2_k127_5377455_1	1267211.KI669560_gene2294	4.867e-71	249.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1IPAV@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_5377455_0	485918.Cpin_1847	2.14e-119	387.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CSH2_k127_5379217_0	619693.HMPREF6745_1917	2.031e-59	228.0	COG0438@1|root,COG0438@2|Bacteria,4PIFN@976|Bacteroidetes,2FT6Y@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_5388175_1	688270.Celal_4232	7.825e-88	300.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes,1I2DH@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CSH2_k127_5388175_0	1492737.FEM08_01140	5.393e-162	521.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,1HWT3@117743|Flavobacteriia,2NSBP@237|Flavobacterium	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
CSH2_k127_5388175_2	1239962.C943_00987	1.702e-62	216.0	COG0252@1|root,COG0252@2|Bacteria,4NFKG@976|Bacteroidetes,47MY9@768503|Cytophagia	976|Bacteroidetes	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CSH2_k127_5392903_2	700598.Niako_2452	8.186e-146	467.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1INWN@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_5392903_0	700598.Niako_2097	0.0	1069.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CSH2_k127_5392903_1	485918.Cpin_1916	3.856e-153	489.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IP9D@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CSH2_k127_540109_0	925409.KI911562_gene2283	8.594e-98	332.0	COG1629@1|root,COG1629@2|Bacteria,4P4MW@976|Bacteroidetes,1IP27@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
CSH2_k127_540109_1	700598.Niako_2175	3.494e-50	182.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CSH2_k127_5401177_0	925409.KI911562_gene362	4.482e-60	214.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1INPB@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CSH2_k127_5401177_1	925409.KI911562_gene361	1.633e-12	72.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CSH2_k127_5403552_2	1123248.KB893332_gene2254	4.913e-05	47.0	COG1131@1|root,COG1131@2|Bacteria,4NPDD@976|Bacteroidetes,1J1AC@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_5403552_0	700598.Niako_6916	6.548e-94	316.0	COG1277@1|root,COG1277@2|Bacteria,4NICG@976|Bacteroidetes	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CSH2_k127_5403552_1	700598.Niako_1936	1.949e-34	134.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1IPSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CSH2_k127_540662_0	1121481.AUAS01000005_gene1804	1.059e-146	482.0	COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,47MN6@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CSH2_k127_540662_1	929703.KE386491_gene1952	1.477e-65	229.0	COG4221@1|root,COG4221@2|Bacteria,4NHEQ@976|Bacteroidetes,47M62@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_5410094_1	700598.Niako_4703	3.701e-29	117.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IPYS@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM (2R)-phospho-3-sulfolactate synthase ComA	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
CSH2_k127_5410094_0	925409.KI911562_gene13	3.15e-182	579.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CSH2_k127_5412009_2	760192.Halhy_2361	4.277e-41	155.0	29EC5@1|root,301A4@2|Bacteria,4NP7Z@976|Bacteroidetes,1ISJ2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5412009_1	926549.KI421517_gene3362	2.201e-61	223.0	COG0115@1|root,COG0115@2|Bacteria,4PJ29@976|Bacteroidetes,47M6P@768503|Cytophagia	976|Bacteroidetes	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CSH2_k127_5412009_0	1089547.KB913013_gene1403	1.54e-71	249.0	COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,47NYV@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CSH2_k127_5412009_3	1121286.AUMT01000019_gene1805	2.874e-24	107.0	COG2350@1|root,COG2350@2|Bacteria,4NRC1@976|Bacteroidetes,1I447@117743|Flavobacteriia,3ZPYB@59732|Chryseobacterium	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CSH2_k127_5413600_1	1267211.KI669560_gene1447	2.637e-77	263.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
CSH2_k127_5413600_2	1121373.KB903625_gene3175	6.939e-09	58.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,47SPA@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
CSH2_k127_5413600_0	485918.Cpin_0679	3.397e-117	390.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CSH2_k127_5420790_0	1122605.KB893627_gene2928	9e-147	473.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
CSH2_k127_5420790_1	1123248.KB893337_gene2484	2.865e-18	89.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1IPTV@117747|Sphingobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CSH2_k127_5421071_1	700598.Niako_4508	3.569e-115	376.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CSH2_k127_5421071_0	700598.Niako_4507	2.193e-119	386.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
CSH2_k127_5422041_1	700598.Niako_1210	2.632e-70	241.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1ITP3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5422041_0	925409.KI911562_gene1584	5.54e-180	570.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1INZR@117747|Sphingobacteriia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_54389_0	246200.SPO3036	1.305e-223	699.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,4ND2Q@97050|Ruegeria	28211|Alphaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
CSH2_k127_5442042_0	1121904.ARBP01000003_gene6255	2.147e-52	193.0	COG4206@1|root,COG4206@2|Bacteria,4PKFW@976|Bacteroidetes,47Y2Y@768503|Cytophagia	976|Bacteroidetes	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
CSH2_k127_5442042_1	485918.Cpin_3938	1.46e-35	137.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IPIY@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	pabB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CSH2_k127_544404_0	1122223.KB890697_gene1029	1.944e-51	186.0	COG3542@1|root,COG3542@2|Bacteria,1WN4E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
CSH2_k127_544404_1	925409.KI911562_gene579	5.283e-16	78.0	COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1IP0R@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_5447616_0	485918.Cpin_1538	1.214e-128	414.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IV4C@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_5447616_1	1267211.KI669560_gene2552	3.516e-80	271.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_5452527_1	929713.NIASO_19250	2.472e-36	145.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes,1IT1C@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CSH2_k127_5452527_0	925409.KI911562_gene1489	1.763e-49	179.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CSH2_k127_5459501_2	700598.Niako_0343	3.866e-14	79.0	COG0457@1|root,COG0457@2|Bacteria	700598.Niako_0343|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5459501_0	925409.KI911562_gene1879	1.091e-94	314.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1IPVS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CSH2_k127_5459501_1	525373.HMPREF0766_11224	1.774e-30	124.0	COG0010@1|root,COG0010@2|Bacteria,4NEFA@976|Bacteroidetes,1IPC3@117747|Sphingobacteriia	976|Bacteroidetes	E	Arginase family	hutG	-	3.5.3.7,3.5.3.8	ko:K01479,ko:K12255	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045	R01990,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CSH2_k127_5461205_0	468059.AUHA01000003_gene1836	5.569e-98	349.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1IPY8@117747|Sphingobacteriia	976|Bacteroidetes	C	lyase activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
CSH2_k127_5461205_2	1123248.KB893326_gene1525	6.967e-41	155.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes,1IT2A@117747|Sphingobacteriia	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CSH2_k127_5461205_1	1123248.KB893326_gene1524	4.362e-47	176.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1ISTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
CSH2_k127_5461594_0	1047013.AQSP01000142_gene185	2.16e-56	201.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CSH2_k127_5461594_1	925409.KI911562_gene299	2.852e-46	171.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CSH2_k127_5465209_0	1279009.ADICEAN_02492	1.706e-113	370.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,47NZB@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CSH2_k127_5465209_1	1121011.AUCB01000003_gene2521	1.606e-40	150.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1HYGN@117743|Flavobacteriia,23G9J@178469|Arenibacter	976|Bacteroidetes	C	DRTGG domain	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
CSH2_k127_5472425_0	700598.Niako_6443	8.852e-48	184.0	COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,1IWXD@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CSH2_k127_5512215_1	925409.KI911562_gene255	1.452e-92	310.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CSH2_k127_5512215_2	485918.Cpin_1191	1.314e-38	148.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,1ITHM@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5512215_0	925409.KI911562_gene258	9.851e-120	387.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_5520421_0	1267211.KI669560_gene1790	1.297e-203	638.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1IP2N@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein required for spore maturation in B.subtilis	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
CSH2_k127_5522236_2	1267211.KI669560_gene17	1.012e-75	258.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CSH2_k127_5522236_3	1296416.JACB01000003_gene879	3.23e-73	251.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HYK4@117743|Flavobacteriia,2YKDR@290174|Aquimarina	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_5522236_1	468059.AUHA01000002_gene745	7.11e-183	576.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1IUY6@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_5522236_0	929562.Emtol_0667	1.189e-188	598.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47K8N@768503|Cytophagia	976|Bacteroidetes	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CSH2_k127_5533625_0	1123248.KB893359_gene2112	2.272e-157	499.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1IP8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_5533625_1	1267211.KI669560_gene858	4.403e-86	291.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1ISRG@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5533625_2	1123248.KB893359_gene2110	4.769e-20	92.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
CSH2_k127_5547965_1	700598.Niako_5629	7.978e-273	841.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1IPCY@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CSH2_k127_5547965_2	1122605.KB893625_gene2118	3.426e-249	790.0	COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
CSH2_k127_5547965_5	1305737.JAFX01000001_gene1357	5.586e-20	97.0	2CWBN@1|root,32SZD@2|Bacteria,4NU6S@976|Bacteroidetes,47VSE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5547965_4	1123248.KB893322_gene682	2.057e-28	120.0	COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1IU44@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5547965_0	1168034.FH5T_01920	0.0	1164.0	COG3408@1|root,COG3408@2|Bacteria,4NFHH@976|Bacteroidetes,2FQTQ@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
CSH2_k127_5547965_3	1121912.AUHD01000005_gene1843	3.298e-91	308.0	COG0729@1|root,COG0729@2|Bacteria,4PPA8@976|Bacteroidetes	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CSH2_k127_5551152_1	925409.KI911562_gene674	1.958e-12	72.0	2AFQJ@1|root,315SF@2|Bacteria,4NZE3@976|Bacteroidetes,1J018@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5551152_0	1121033.AUCF01000013_gene1686	3.097e-35	137.0	COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,2TXDS@28211|Alphaproteobacteria,2JTYI@204441|Rhodospirillales	204441|Rhodospirillales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_5558558_0	1267211.KI669560_gene1404	1.224e-167	530.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CSH2_k127_556493_1	700598.Niako_6529	5.523e-26	111.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1IQ8Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CSH2_k127_556493_0	700598.Niako_6021	1.48e-112	367.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CSH2_k127_556493_2	485918.Cpin_4539	1.168e-20	93.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IPPS@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CSH2_k127_5565622_0	700598.Niako_6955	4.658e-185	584.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CSH2_k127_5569441_1	1239962.C943_04601	6.029e-28	115.0	COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,47PBG@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CSH2_k127_5569441_0	925409.KI911562_gene613	1.212e-206	647.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
CSH2_k127_5570048_1	700598.Niako_5705	5.434e-69	244.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1ITHJ@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_5570048_3	1267211.KI669560_gene2722	3.516e-37	145.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1IY9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Large-conductance mechanosensitive channel, MscL	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CSH2_k127_5570048_2	1122605.KB893628_gene4451	2.183e-52	197.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1IPAT@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
CSH2_k127_5570048_0	925409.KI911562_gene1450	3.26e-115	376.0	COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,1IPTD@117747|Sphingobacteriia	976|Bacteroidetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CSH2_k127_5579493_0	925409.KI911562_gene1484	1.638e-87	299.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_5579493_1	1408433.JHXV01000002_gene455	3.664e-19	89.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia,2PAN0@246874|Cryomorphaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_5584951_0	929556.Solca_3167	1.189e-63	221.0	COG0110@1|root,COG0110@2|Bacteria,4NNPH@976|Bacteroidetes,1IXS6@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CSH2_k127_5584951_1	1123248.KB893316_gene4526	4e-21	97.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,1IP25@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CSH2_k127_5586090_0	925409.KI911562_gene2529	1.326e-90	301.0	COG0671@1|root,COG0671@2|Bacteria,4NGYP@976|Bacteroidetes,1IR1B@117747|Sphingobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CSH2_k127_5586090_1	760192.Halhy_5194	2.479e-27	113.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,1IVK3@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CSH2_k127_5586576_0	925409.KI911562_gene2250	5.003e-128	421.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,1IR4H@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CSH2_k127_5590746_2	714943.Mucpa_2150	4.876e-82	276.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1IPZS@117747|Sphingobacteriia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
CSH2_k127_5590746_0	1123248.KB893321_gene484	6.67e-204	644.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPDG@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CSH2_k127_5590746_1	1123248.KB893321_gene485	2.143e-164	528.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1IPUP@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
CSH2_k127_5590746_4	925409.KI911562_gene840	1.769e-45	172.0	COG3897@1|root,COG3897@2|Bacteria,4P696@976|Bacteroidetes,1IZ1E@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
CSH2_k127_5590746_3	485917.Phep_2046	9.719e-54	194.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1IR0G@117747|Sphingobacteriia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
CSH2_k127_5591809_0	1267211.KI669560_gene2394	8.743e-124	406.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1INS9@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CSH2_k127_5595342_0	1267211.KI669560_gene865	6.287e-162	518.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IQIN@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CSH2_k127_5597777_2	1122605.KB893628_gene4454	3.954e-07	53.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1IQVW@117747|Sphingobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5597777_0	925409.KI911562_gene559	6.79e-197	619.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,1INXS@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CSH2_k127_5597777_1	925409.KI911562_gene558	1.184e-154	491.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,1INV1@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CSH2_k127_5607105_0	1267211.KI669560_gene1215	1.162e-89	303.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CSH2_k127_5607105_1	929556.Solca_2020	1.974e-87	290.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CSH2_k127_5613199_1	925409.KI911562_gene565	4.335e-122	399.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1IRVU@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CSH2_k127_5613199_0	1123248.KB893348_gene138	8.478e-162	516.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1IP7N@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CSH2_k127_5613199_2	1121889.AUDM01000002_gene423	7.65e-08	62.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1I2RK@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
CSH2_k127_5616282_0	925409.KI911562_gene1110	9.485e-162	511.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1INWJ@117747|Sphingobacteriia	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CSH2_k127_5616282_1	1123248.KB893314_gene3428	3.46e-85	287.0	COG0491@1|root,COG0491@2|Bacteria,4NHW8@976|Bacteroidetes,1IQ1J@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CSH2_k127_5620639_0	1122605.KB893648_gene3597	7.213e-87	288.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1IRJ7@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CSH2_k127_5620639_1	1267211.KI669560_gene1313	1.083e-71	245.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1ISHA@117747|Sphingobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CSH2_k127_5620639_2	867845.KI911784_gene1631	1.208e-08	60.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi,375N7@32061|Chloroflexia	32061|Chloroflexia	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
CSH2_k127_5622393_1	925409.KI911562_gene1530	3.381e-39	150.0	COG0738@1|root,COG0738@2|Bacteria,4NFHM@976|Bacteroidetes,1IRGQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_5622393_0	945713.IALB_2990	7.419e-60	215.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4397
CSH2_k127_5622916_2	700598.Niako_7332	7.535e-13	68.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CSH2_k127_5622916_0	760192.Halhy_0703	1.137e-65	229.0	COG3182@1|root,COG3182@2|Bacteria,4NP61@976|Bacteroidetes,1IXNR@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
CSH2_k127_5622916_1	491205.JARQ01000004_gene2585	1.226e-17	83.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,1HYW6@117743|Flavobacteriia,3ZRB9@59732|Chryseobacterium	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CSH2_k127_5630753_1	1267211.KI669560_gene1749	8.03e-07	51.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,1IQ1U@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
CSH2_k127_5630753_0	468059.AUHA01000002_gene1152	2.727e-62	227.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1IPH4@117747|Sphingobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	cap5D	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CSH2_k127_5638027_0	1270196.JCKI01000004_gene1117	1.414e-136	452.0	COG3637@1|root,COG3637@2|Bacteria,4PM31@976|Bacteroidetes	976|Bacteroidetes	M	SusD family	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
CSH2_k127_5638027_1	925409.KI911562_gene376	1.091e-83	291.0	COG0526@1|root,COG0526@2|Bacteria,4NQ06@976|Bacteroidetes,1ISI1@117747|Sphingobacteriia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
CSH2_k127_5638027_2	1267211.KI669560_gene34	7.249e-24	102.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1INQU@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CSH2_k127_5640123_1	760192.Halhy_0874	3.107e-89	299.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IR88@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CSH2_k127_5640123_0	700598.Niako_1689	4.179e-95	317.0	COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,1IPRU@117747|Sphingobacteriia	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CSH2_k127_5642459_1	700598.Niako_5645	2.328e-81	276.0	COG1018@1|root,COG1018@2|Bacteria,4PN6Y@976|Bacteroidetes	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523,ko:K05784	ko00362,ko00364,ko00520,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00520,map00622,map01100,map01120,map01220	M00551	R03391,R03392,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110	RC00230,RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CSH2_k127_5642459_0	1123248.KB893386_gene1984	1.374e-88	296.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CSH2_k127_5654077_5	1267535.KB906767_gene1458	3.324e-14	72.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CSH2_k127_5654077_3	471854.Dfer_2354	1.781e-78	269.0	COG3279@1|root,COG3279@2|Bacteria,4NH5N@976|Bacteroidetes,47N4M@768503|Cytophagia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CSH2_k127_5654077_0	1123278.KB893412_gene2910	2.664e-133	462.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_5654077_4	471854.Dfer_3346	2.135e-52	203.0	COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,47Y7S@768503|Cytophagia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CSH2_k127_5654077_2	471854.Dfer_2354	2.094e-85	289.0	COG3279@1|root,COG3279@2|Bacteria,4NH5N@976|Bacteroidetes,47N4M@768503|Cytophagia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CSH2_k127_5654077_1	471854.Dfer_2353	6.263e-88	311.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_5654077_6	1185876.BN8_00055	1.4e-07	60.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,47MVY@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_5654717_1	1267211.KI669560_gene2164	1.272e-36	146.0	COG3637@1|root,COG3637@2|Bacteria,4NWNN@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
CSH2_k127_5654717_0	925409.KI911562_gene2784	1.709e-209	658.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1IQDQ@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CSH2_k127_5656249_0	700598.Niako_5599	1.492e-183	586.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IQR9@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CSH2_k127_5656249_2	1123248.KB893322_gene574	1.417e-26	109.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IUFV@117747|Sphingobacteriia	976|Bacteroidetes	U	Sec-independent protein translocase protein TatA	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CSH2_k127_5656249_1	1123248.KB893322_gene575	1.964e-53	192.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1ITCV@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CSH2_k127_5681604_2	1123073.KB899241_gene2695	2.205e-06	50.0	COG0454@1|root,COG0456@2|Bacteria,1QB34@1224|Proteobacteria,1T6KQ@1236|Gammaproteobacteria,1X7QI@135614|Xanthomonadales	135614|Xanthomonadales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_5681604_1	1121373.KB903636_gene805	7.847e-09	58.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CSH2_k127_5681604_0	1121373.KB903636_gene804	6.989e-52	196.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,47NEW@768503|Cytophagia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CSH2_k127_56840_3	700598.Niako_6544	2.507e-43	163.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,1IWWU@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
CSH2_k127_56840_0	1123248.KB893348_gene342	6.394e-146	465.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1INN5@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CSH2_k127_56840_4	485918.Cpin_2572	1.079e-10	63.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CSH2_k127_56840_2	700598.Niako_6631	3.46e-69	243.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CSH2_k127_56840_1	700598.Niako_6632	8.424e-114	383.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_5687799_1	106582.XP_004556910.1	9.226e-08	61.0	28K69@1|root,2SPI9@2759|Eukaryota,3AMQ9@33154|Opisthokonta,3C85Z@33208|Metazoa,3DH73@33213|Bilateria,48K5F@7711|Chordata,49H9C@7742|Vertebrata,4A7X1@7898|Actinopterygii	33208|Metazoa	S	Complement component C1q domain.	-	-	-	-	-	-	-	-	-	-	-	-	C1q
CSH2_k127_5687799_0	1123057.P872_07640	4.366e-145	467.0	COG0252@1|root,COG0252@2|Bacteria,4NFKG@976|Bacteroidetes,47MY9@768503|Cytophagia	976|Bacteroidetes	EJ	Asparaginase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CSH2_k127_5692025_0	929713.NIASO_15895	7.725e-129	415.0	COG2303@1|root,COG2303@2|Bacteria,4NHJT@976|Bacteroidetes,1IRDW@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CSH2_k127_5692025_1	1123277.KB893217_gene4574	4.817e-37	145.0	COG2259@1|root,COG2259@2|Bacteria,4P48I@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CSH2_k127_5706502_1	1123248.KB893324_gene1764	4.239e-37	152.0	28ICP@1|root,314Q6@2|Bacteria,4PIZD@976|Bacteroidetes,1IZ0B@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5706502_0	925409.KI911562_gene60	2.386e-65	225.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
CSH2_k127_5706775_0	1267211.KI669560_gene1216	3.42e-139	448.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CSH2_k127_5706775_1	1267211.KI669560_gene1215	1.049e-36	142.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CSH2_k127_5719071_1	929562.Emtol_0696	1.992e-108	353.0	COG0031@1|root,COG0031@2|Bacteria,4NF7E@976|Bacteroidetes,47J9D@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CSH2_k127_5719071_0	468059.AUHA01000002_gene113	1.626e-113	374.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1IPAM@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CSH2_k127_5719071_2	700598.Niako_4328	3.83e-62	218.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CSH2_k127_5725326_0	1239962.C943_01001	3.884e-115	376.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,47M9U@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CSH2_k127_5725326_1	929556.Solca_4205	7.037e-79	265.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPE6@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CSH2_k127_5733709_1	484018.BACPLE_03414	7.255e-12	73.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,2FMHG@200643|Bacteroidia,4AKHV@815|Bacteroidaceae	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
CSH2_k127_5733709_0	762903.Pedsa_2838	7.784e-60	218.0	COG2887@1|root,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1IWFK@117747|Sphingobacteriia	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CSH2_k127_5735216_0	396588.Tgr7_1955	1.69e-78	271.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1RMDN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	N-acetylmuramoyl-L-alanine amidase	amiD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.16.4,3.5.1.28	ko:K01447,ko:K11066,ko:K21469	ko00550,map00550	-	R04112	RC00064,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Amidase_2,PG_binding_1
CSH2_k127_5735216_1	925409.KI911562_gene2381	4.234e-11	68.0	COG5412@1|root,COG5412@2|Bacteria,4NJXH@976|Bacteroidetes,1IX5R@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Endonuclea_NS_2
CSH2_k127_5737335_0	335543.Sfum_1027	1.468e-14	86.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	COP23,N-glycanase_C,Trypsin_2
CSH2_k127_57605_0	1123248.KB893326_gene1486	2.25e-96	321.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,1ISEP@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_5782879_0	1123248.KB893315_gene3152	8.587e-201	628.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CSH2_k127_5785388_0	1346330.M472_00600	1.34e-99	334.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IPM0@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
CSH2_k127_5785388_2	1123248.KB893317_gene4320	5.724e-05	46.0	COG0265@1|root,COG0265@2|Bacteria,4NGA4@976|Bacteroidetes,1IPPQ@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CSH2_k127_579258_0	700598.Niako_7330	1.452e-92	310.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1IVCP@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_579258_1	700598.Niako_7329	2.421e-48	180.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,1IZB2@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
CSH2_k127_5795617_2	485918.Cpin_6979	1.078e-26	111.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_5795617_0	1122605.KB893630_gene4065	1.428e-114	378.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_5795617_1	700598.Niako_7323	4.368e-114	376.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CSH2_k127_5796179_2	1382358.JHVN01000006_gene106	8.812e-10	59.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,21WKH@150247|Anoxybacillus	91061|Bacilli	I	Beta-ketoacyl synthase, N-terminal domain	pcaF	-	2.3.1.174,2.3.1.223	ko:K02615	ko00360,ko01120,map00360,map01120	-	R00829,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko01000	-	-	-	Thiolase_C,Thiolase_N
CSH2_k127_5796179_0	1267211.KI669560_gene2235	2.212e-59	217.0	COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,1IXG8@117747|Sphingobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_5797272_0	929556.Solca_2062	2.6e-105	353.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,1IPNA@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	aefA	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
CSH2_k127_5800478_0	925409.KI911562_gene1591	5.47e-166	533.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CSH2_k127_5803374_0	700598.Niako_5604	6.368e-159	506.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CSH2_k127_5811554_1	485917.Phep_1372	8.073e-47	175.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1ITIM@117747|Sphingobacteriia	976|Bacteroidetes	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CSH2_k127_5811554_0	1408433.JHXV01000007_gene2837	4.617e-49	177.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1HXPE@117743|Flavobacteriia,2PA8D@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.11	ko:K01758,ko:K01761	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00654,R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00196,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CSH2_k127_58135_1	1123248.KB893315_gene3102	2.079e-55	203.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IT0W@117747|Sphingobacteriia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CSH2_k127_58135_0	700598.Niako_6969	3.698e-166	525.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_58135_2	925409.KI911562_gene1270	4.377e-35	134.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_58135_4	880071.Fleli_2504	1.934e-17	87.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia	976|Bacteroidetes	C	PFAM Class III cytochrome C family	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
CSH2_k127_58135_3	1150600.ADIARSV_0770	2.053e-31	128.0	COG1393@1|root,COG1393@2|Bacteria,4NSJ5@976|Bacteroidetes,1ITCN@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
CSH2_k127_5814062_1	1122605.KB893631_gene3948	2.526e-11	64.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CSH2_k127_5814062_0	700598.Niako_5288	1.257e-70	244.0	COG0664@1|root,COG0664@2|Bacteria,4NM5E@976|Bacteroidetes,1IS1K@117747|Sphingobacteriia	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CSH2_k127_5815200_1	925409.KI911562_gene1438	2.21e-06	49.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1IS6G@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CSH2_k127_5815200_0	1123248.KB893386_gene1902	1.336e-148	478.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1IPSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CSH2_k127_5821911_0	945713.IALB_0272	2.488e-123	402.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CSH2_k127_5821911_1	945713.IALB_0271	1.45e-22	101.0	COG1036@1|root,COG1036@2|Bacteria	2|Bacteria	C	dihydromethanopterin reductase activity	rnfB	-	1.2.7.3	ko:K00176,ko:K03616	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	FeS,Fer4,Fer4_7
CSH2_k127_5821911_2	65393.PCC7424_2217	3.772e-05	55.0	2FF99@1|root,34773@2|Bacteria	2|Bacteria	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CSH2_k127_5829369_0	1267211.KI669560_gene2871	1.72e-219	687.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_5831331_0	1123248.KB893385_gene4879	1.681e-225	710.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1IQ58@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CSH2_k127_5831331_1	1267211.KI669560_gene2729	5.67e-70	244.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1IS92@117747|Sphingobacteriia	976|Bacteroidetes	T	Molecular chaperone DnaK	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CSH2_k127_5833712_1	1270196.JCKI01000009_gene3386	7.426e-68	241.0	COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1IY37@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CSH2_k127_5833712_0	1267211.KI669560_gene1021	9.797e-192	609.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_5836199_1	1242864.D187_008417	5.303e-09	68.0	COG0793@1|root,COG0793@2|Bacteria,1RCVK@1224|Proteobacteria	1224|Proteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CSH2_k127_5836199_0	485918.Cpin_0844	8.304e-202	631.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_5840783_0	1123248.KB893316_gene4628	1.127e-175	569.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes,1IRMG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5841631_0	485918.Cpin_2323	1.79e-300	931.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,1IPCR@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CSH2_k127_5843777_1	153721.MYP_3912	1.119e-49	179.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,47Q8F@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
CSH2_k127_5843777_0	925409.KI911562_gene437	6.027e-84	289.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1IPE9@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
CSH2_k127_58476_8	742726.HMPREF9448_02469	0.0005948	42.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,2FTXY@200643|Bacteroidia,22YB5@171551|Porphyromonadaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CSH2_k127_58476_7	700598.Niako_4675	1.899e-23	102.0	COG0255@1|root,COG0255@2|Bacteria,4P9VV@976|Bacteroidetes,1IU24@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CSH2_k127_58476_3	925409.KI911562_gene3027	6.29e-75	252.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1IRSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CSH2_k127_58476_1	700598.Niako_4677	5.044e-132	424.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1IPKE@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CSH2_k127_58476_4	929713.NIASO_08520	4.178e-50	179.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,1ISMN@117747|Sphingobacteriia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CSH2_k127_58476_5	925409.KI911562_gene3030	5.461e-44	162.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1ISXF@117747|Sphingobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CSH2_k127_58476_0	1267211.KI669560_gene1320	1.3e-149	476.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1INT6@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CSH2_k127_58476_6	485918.Cpin_1617	7.46e-37	141.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,1ITE2@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CSH2_k127_58476_2	1123248.KB893314_gene3324	1.538e-80	271.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,1IRTU@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CSH2_k127_5849086_0	700598.Niako_5718	4.962e-108	356.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1IQ8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CSH2_k127_5849086_1	1122605.KB893626_gene2535	4.118e-96	325.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CSH2_k127_5854232_0	925409.KI911562_gene625	3.146e-111	362.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1IQPD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CSH2_k127_5854232_2	925409.KI911562_gene624	1.087e-90	307.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1IS1R@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
CSH2_k127_5854232_1	1267211.KI669560_gene385	1.698e-99	333.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1IS2B@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CSH2_k127_5854232_4	927658.AJUM01000037_gene2121	1.862e-21	107.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,2FNIX@200643|Bacteroidia,3XJRZ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_5854232_3	1267211.KI669560_gene387	1.346e-75	267.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IPS5@117747|Sphingobacteriia	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_5857674_2	700598.Niako_1561	8.956e-43	166.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,1IYEN@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CSH2_k127_5857674_5	1168289.AJKI01000004_gene2926	1.208e-14	78.0	COG2827@1|root,COG2827@2|Bacteria,4P9EH@976|Bacteroidetes,2FZ8T@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CSH2_k127_5857674_6	1174504.AJTN02000120_gene4835	8.977e-07	53.0	2BR4S@1|root,32K2S@2|Bacteria,1U1SU@1239|Firmicutes,4IB95@91061|Bacilli,1ZKR2@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5857674_4	760192.Halhy_5034	2.297e-26	112.0	2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CSH2_k127_5857674_0	1267211.KI669560_gene266	1.75e-134	447.0	COG1807@1|root,COG1807@2|Bacteria,4NKI5@976|Bacteroidetes,1J09F@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CSH2_k127_5857674_1	700598.Niako_5494	9.575e-118	388.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_5857674_3	700598.Niako_5493	1.053e-39	151.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_5858501_0	1123276.KB893250_gene349	1.13e-164	527.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_5858771_0	1166018.FAES_4074	3.411e-42	158.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,47NMH@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CSH2_k127_5858771_1	857293.CAAU_1831	4.053e-18	92.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,25CN4@186801|Clostridia,36WY7@31979|Clostridiaceae	186801|Clostridia	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CSH2_k127_5860474_0	1267211.KI669560_gene1423	2.699e-42	159.0	COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes,1IYKP@117747|Sphingobacteriia	976|Bacteroidetes	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
CSH2_k127_5860474_1	1227360.C176_00945	3.251e-42	160.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HKC0@91061|Bacilli,26FIX@186818|Planococcaceae	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt3	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CSH2_k127_5860474_2	391603.FBALC1_06433	1.503e-31	126.0	COG0346@1|root,COG0346@2|Bacteria,4NQRN@976|Bacteroidetes,1I2S1@117743|Flavobacteriia	976|Bacteroidetes	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
CSH2_k127_5862700_0	555088.DealDRAFT_2880	2.816e-106	353.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes	1239|Firmicutes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CSH2_k127_5863696_1	1506583.JQJY01000008_gene4073	4.713e-35	142.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CSH2_k127_5863696_0	700598.Niako_1953	2.492e-87	317.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_5872407_1	1123248.KB893359_gene2053	1.44e-104	342.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CSH2_k127_5873071_0	1120965.AUBV01000004_gene977	1.246e-115	383.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,47XGE@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CSH2_k127_5873071_1	1120965.AUBV01000014_gene1243	2.912e-112	364.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CSH2_k127_5876961_1	700598.Niako_2206	4.397e-44	166.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CSH2_k127_5876961_0	929713.NIASO_00855	8.529e-99	327.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
CSH2_k127_5882250_1	471854.Dfer_4322	6.985e-36	139.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
CSH2_k127_5882250_0	471854.Dfer_4322	9.63e-104	349.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
CSH2_k127_5890583_0	1121904.ARBP01000013_gene309	4.37e-21	102.0	COG1226@1|root,32Y28@2|Bacteria	2|Bacteria	P	Ion transport 2 domain protein	RB9536	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
CSH2_k127_5890583_1	1123070.KB899252_gene857	9.652e-14	81.0	COG0628@1|root,COG0628@2|Bacteria,46WM9@74201|Verrucomicrobia	2|Bacteria	S	Pfam:UPF0118	MA20_41055	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CSH2_k127_5891824_0	700598.Niako_2627	6.082e-165	522.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1IPW9@117747|Sphingobacteriia	976|Bacteroidetes	J	elongation factor G domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_5894443_0	746697.Aeqsu_1825	0.0004856	52.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI1V@976|Bacteroidetes,1HWSH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
CSH2_k127_590741_1	700598.Niako_6852	4.514e-54	192.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1IPP4@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CSH2_k127_590741_2	700598.Niako_6851	3.494e-38	156.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,1IUMD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
CSH2_k127_590741_0	1123248.KB893325_gene1158	5.448e-91	307.0	COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,1J0U3@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA,ShlB
CSH2_k127_5911660_0	1250232.JQNJ01000001_gene1503	3.045e-200	632.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,1HZF1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	malL	-	3.2.1.1,3.2.1.10,5.4.99.16	ko:K01182,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
CSH2_k127_5912587_1	742767.HMPREF9456_01660	4.513e-49	177.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia,22XSZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CSH2_k127_5912587_0	1123248.KB893322_gene627	3.142e-124	406.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1IX4W@117747|Sphingobacteriia	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CSH2_k127_591991_1	1123248.KB893385_gene4853	2.802e-106	355.0	28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,1IRCZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CSH2_k127_591991_0	700598.Niako_0114	2.541e-303	945.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQWY@117747|Sphingobacteriia	976|Bacteroidetes	E	ACT domain	thrA	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
CSH2_k127_5934993_0	1121382.JQKG01000016_gene1589	1.32e-51	194.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CSH2_k127_594337_0	1123248.KB893348_gene304	1.851e-98	332.0	COG3206@1|root,COG3206@2|Bacteria,4P3QF@976|Bacteroidetes	976|Bacteroidetes	M	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
CSH2_k127_594337_2	1124780.ANNU01000044_gene503	1.621e-11	74.0	2AFQQ@1|root,315SK@2|Bacteria,4NJD4@976|Bacteroidetes,47PFM@768503|Cytophagia	976|Bacteroidetes	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
CSH2_k127_594337_1	1461577.CCMH01000008_gene2235	1.967e-17	91.0	2AFQQ@1|root,315SK@2|Bacteria,4NS2X@976|Bacteroidetes,1I3KK@117743|Flavobacteriia	976|Bacteroidetes	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
CSH2_k127_594939_2	925409.KI911562_gene1496	1.652e-31	124.0	COG0626@1|root,COG0626@2|Bacteria,4NJRK@976|Bacteroidetes,1IP3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CSH2_k127_594939_1	1239962.C943_03721	1.32e-175	569.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,47NUP@768503|Cytophagia	976|Bacteroidetes	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CSH2_k127_594939_0	700598.Niako_5085	6.084e-236	741.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IVVS@117747|Sphingobacteriia	976|Bacteroidetes	Q	COGs COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CSH2_k127_594939_3	929713.NIASO_19645	5.026e-14	72.0	COG1247@1|root,COG1247@2|Bacteria,4PM4N@976|Bacteroidetes,1ISGA@117747|Sphingobacteriia	976|Bacteroidetes	M	Gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_5951294_0	1123248.KB893348_gene233	8.27e-158	502.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_5956406_0	925409.KI911562_gene1876	6.614e-198	632.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,1IP8M@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
CSH2_k127_5957755_0	1123248.KB893385_gene4819	5.363e-86	300.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1IP8T@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CSH2_k127_5958633_0	700598.Niako_6291	7.629e-34	140.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5958633_1	1121859.KB890750_gene381	2.405e-17	87.0	2C7HJ@1|root,309CJ@2|Bacteria,4NPTZ@976|Bacteroidetes,47X8T@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CSH2_k127_5963346_1	1123277.KB893239_gene1208	3.466e-48	176.0	COG5285@1|root,COG5285@2|Bacteria,4NGMY@976|Bacteroidetes,47MFK@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CSH2_k127_5963346_0	1122605.KB893646_gene66	7.197e-80	274.0	COG2207@1|root,COG2207@2|Bacteria,4NEVG@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CSH2_k127_5968756_2	925409.KI911562_gene302	1.641e-26	109.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_5968756_1	946077.W5A_04014	1.066e-27	116.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,1I40T@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CSH2_k127_5968756_0	925409.KI911562_gene929	4.982e-201	636.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1IR2H@117747|Sphingobacteriia	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	betC_2	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CSH2_k127_5974344_0	1267211.KI669560_gene1636	1.826e-126	406.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1IQ1B@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome C oxidase subunit II, periplasmic domain	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CSH2_k127_5974344_1	929713.NIASO_09250	2.733e-68	237.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1ISPY@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CSH2_k127_5976075_1	1120951.AUBG01000006_gene517	1.936e-32	130.0	COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1HZPZ@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CSH2_k127_5976075_0	925409.KI911562_gene752	3.309e-77	262.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CSH2_k127_5978507_0	925409.KI911562_gene2902	2.398e-195	611.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1IP5T@117747|Sphingobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CSH2_k127_5983322_0	1123248.KB893317_gene4313	3.452e-262	827.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_5983322_2	1185876.BN8_01684	1.128e-27	125.0	COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,47P9G@768503|Cytophagia	976|Bacteroidetes	M	PFAM Fasciclin domain	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	Fasciclin
CSH2_k127_5983322_1	700598.Niako_1591	4.239e-84	280.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CSH2_k127_5988206_1	886379.AEWI01000211_gene2501	5.777e-70	244.0	COG1051@1|root,COG1051@2|Bacteria,4NIBP@976|Bacteroidetes,2FNT4@200643|Bacteroidia,3XJ7M@558415|Marinilabiliaceae	976|Bacteroidetes	F	Hydrolase, NUDIX family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CSH2_k127_5988206_0	927658.AJUM01000022_gene1113	5.673e-119	389.0	COG2211@1|root,COG2211@2|Bacteria,4NE3B@976|Bacteroidetes,2FPMF@200643|Bacteroidia,3XIK2@558415|Marinilabiliaceae	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CSH2_k127_5998690_0	1122605.KB893643_gene604	1.255e-87	304.0	28M10@1|root,2ZAFW@2|Bacteria,4NIF8@976|Bacteroidetes,1ISGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
CSH2_k127_5998690_1	445961.IW15_15220	2.671e-14	77.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1HYN3@117743|Flavobacteriia,3ZSE7@59732|Chryseobacterium	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CSH2_k127_600314_0	1223410.KN050846_gene2267	7.789e-46	186.0	COG0729@1|root,COG5295@1|root,COG0729@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CSH2_k127_6004217_1	700598.Niako_5740	7.52e-06	52.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1IQCU@117747|Sphingobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CSH2_k127_6004217_0	700598.Niako_5741	1.91e-75	265.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1IVTD@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component regulator propeller domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CSH2_k127_6008712_0	1122605.KB893625_gene2000	1.59e-108	358.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1IQJK@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CSH2_k127_6008712_1	925409.KI911562_gene2792	2.949e-68	233.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1IQ18@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CSH2_k127_6020840_0	925409.KI911562_gene1585	3.884e-268	829.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IV39@117747|Sphingobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CSH2_k127_6020840_1	1122621.ATZA01000047_gene3388	2.576e-79	266.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IPA2@117747|Sphingobacteriia	976|Bacteroidetes	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CSH2_k127_602918_0	1267211.KI669560_gene708	8.151e-140	449.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CSH2_k127_603049_0	926549.KI421517_gene4076	6.943e-13	78.0	28JU1@1|root,2Z9J4@2|Bacteria,4NV4K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
CSH2_k127_6030985_0	1267211.KI669560_gene2080	3.617e-187	586.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1IPEN@117747|Sphingobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CSH2_k127_6037444_0	760192.Halhy_0886	8.917e-223	702.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IWHI@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease PDZ domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_6037674_2	1123248.KB893330_gene411	3.47e-60	211.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IPWF@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CSH2_k127_6037674_1	1123248.KB893330_gene410	6.306e-73	248.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CSH2_k127_6037674_0	945713.IALB_0194	1.993e-92	312.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,YdjC
CSH2_k127_6041727_0	1123248.KB893314_gene3546	0.0	2355.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1IP5J@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CSH2_k127_6045059_1	925409.KI911562_gene1827	1.038e-104	349.0	COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,1IQSZ@117747|Sphingobacteriia	976|Bacteroidetes	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CSH2_k127_6045059_0	1123248.KB893359_gene2069	7.694e-168	545.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CSH2_k127_6045198_1	485918.Cpin_1904	4.361e-74	251.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1IRF3@117747|Sphingobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CSH2_k127_6045198_0	925409.KI911562_gene2807	9.899e-90	298.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1IP51@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CSH2_k127_6051523_0	925409.KI911562_gene2381	0.0	1092.0	COG5412@1|root,COG5412@2|Bacteria,4NJXH@976|Bacteroidetes,1IX5R@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Endonuclea_NS_2
CSH2_k127_6054534_0	700598.Niako_0044	2.035e-36	143.0	COG2928@1|root,COG2928@2|Bacteria,4NT13@976|Bacteroidetes	976|Bacteroidetes	S	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6054534_1	761193.Runsl_0080	1.256e-15	83.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
CSH2_k127_6061256_0	929713.NIASO_00720	1.23e-208	652.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1INYW@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CSH2_k127_607037_0	925409.KI911562_gene2430	2.467e-244	763.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CSH2_k127_6074866_3	1123248.KB893370_gene5078	9.651e-07	52.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,1IP8V@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CSH2_k127_6074866_1	925409.KI911562_gene2778	3.169e-109	361.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,1ISQ1@117747|Sphingobacteriia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CSH2_k127_6074866_0	925409.KI911562_gene2779	7.547e-137	439.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1INX0@117747|Sphingobacteriia	976|Bacteroidetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
CSH2_k127_6074866_2	700598.Niako_4513	7.636e-18	90.0	2F5WP@1|root,33YFF@2|Bacteria,4P47E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6076618_2	925409.KI911562_gene2430	9.041e-33	131.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CSH2_k127_6076618_1	925409.KI911562_gene1998	3.511e-40	154.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1IT35@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CSH2_k127_6076618_0	313606.M23134_05584	6.971e-50	183.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47MAI@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_6086710_0	929713.NIASO_19710	4.942e-100	329.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CSH2_k127_6086710_1	1297742.A176_02167	1.124e-66	239.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CSH2_k127_6094149_0	317936.Nos7107_4209	9.414e-32	132.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CSH2_k127_6094149_1	313606.M23134_04250	2.384e-20	98.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,47KEU@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CSH2_k127_6096442_1	700598.Niako_4718	7.055e-166	527.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1INRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
CSH2_k127_6096442_4	1267211.KI669560_gene24	2.247e-20	96.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1ITXJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6096442_6	485918.Cpin_0185	7.456e-12	74.0	2DQR9@1|root,3387K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6096442_3	700598.Niako_6880	1.37e-88	295.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,1IQKN@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_6096442_5	1267211.KI669560_gene853	1.743e-15	79.0	COG1476@1|root,COG1476@2|Bacteria,4NWX1@976|Bacteroidetes,1IZC8@117747|Sphingobacteriia	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CSH2_k127_6096442_0	1267211.KI669560_gene685	5.52e-182	572.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1IR3A@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CSH2_k127_6096442_2	925409.KI911562_gene295	3.406e-138	443.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CSH2_k127_6101269_1	925409.KI911562_gene2586	2.784e-52	192.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_6101269_0	925409.KI911562_gene2583	1.092e-64	230.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1IRW3@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NlpC P60 family	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
CSH2_k127_6101269_2	925409.KI911562_gene2581	3.601e-10	61.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,1IQEI@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CSH2_k127_6102675_1	485918.Cpin_3134	6.415e-56	199.0	COG0500@1|root,COG2226@2|Bacteria,4NURU@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CSH2_k127_6102675_0	1121904.ARBP01000001_gene5755	2.449e-76	261.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes,47SZD@768503|Cytophagia	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
CSH2_k127_6102675_2	1268622.AVS7_03518	3.469e-08	55.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2VHNI@28216|Betaproteobacteria,4A9W4@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CSH2_k127_6114634_1	925409.KI911562_gene248	1.212e-93	309.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1IQ54@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CSH2_k127_6114634_2	700598.Niako_7027	6.612e-52	187.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,1ISBI@117747|Sphingobacteriia	976|Bacteroidetes	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CSH2_k127_6114634_0	700598.Niako_2543	3.664e-159	512.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CSH2_k127_6114634_3	925409.KI911562_gene2210	4.236e-49	180.0	2ADZU@1|root,313SD@2|Bacteria,4PK7E@976|Bacteroidetes,1IUKW@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
CSH2_k127_6116506_0	1123248.KB893319_gene4042	1.045e-197	625.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1IQGD@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
CSH2_k127_6125193_0	700598.Niako_7327	5.792e-145	470.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1IR5B@117747|Sphingobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CSH2_k127_6125891_0	925409.KI911562_gene379	1.952e-219	694.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,1IQCU@117747|Sphingobacteriia	976|Bacteroidetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CSH2_k127_6125891_1	1434325.AZQN01000006_gene3269	5.165e-17	84.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KF4@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CSH2_k127_6133489_2	1168034.FH5T_08540	0.0001907	45.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,2FMHS@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	amyA2	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
CSH2_k127_6133489_0	1267211.KI669560_gene1453	4.742e-54	199.0	28NAE@1|root,2ZBE7@2|Bacteria,4NJNX@976|Bacteroidetes,1IS37@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
CSH2_k127_6133489_1	1123248.KB893381_gene1092	6.534e-54	198.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1IQ3X@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
CSH2_k127_6136155_2	700598.Niako_0416	4.701e-48	173.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CSH2_k127_6136155_1	929713.NIASO_09790	1.05e-82	280.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1IRSP@117747|Sphingobacteriia	976|Bacteroidetes	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
CSH2_k127_6136155_0	468059.AUHA01000003_gene1685	1.844e-142	459.0	COG2271@1|root,COG2271@2|Bacteria,4NG3R@976|Bacteroidetes,1IW8Q@117747|Sphingobacteriia	976|Bacteroidetes	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
CSH2_k127_6143366_0	925409.KI911562_gene1022	1.499e-126	406.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1IPZE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CSH2_k127_6143366_1	1123248.KB893319_gene3967	6.603e-122	398.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1IRUR@117747|Sphingobacteriia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CSH2_k127_6143366_2	1123248.KB893319_gene3968	7.068e-68	235.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1IST1@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CSH2_k127_6143366_3	1122605.KB893626_gene2525	8.792e-68	233.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1INPX@117747|Sphingobacteriia	976|Bacteroidetes	C	oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CSH2_k127_61458_1	714943.Mucpa_5102	1.276e-53	197.0	COG0156@1|root,COG0156@2|Bacteria,4NKC1@976|Bacteroidetes,1IS9B@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CSH2_k127_61458_0	1121373.KB903628_gene1393	2.249e-88	296.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47KBZ@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
CSH2_k127_6149362_1	693979.Bache_0687	4.498e-26	115.0	COG4249@1|root,COG4249@2|Bacteria,4NS33@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
CSH2_k127_6149362_0	1267211.KI669560_gene309	2.369e-85	288.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1IQZH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
CSH2_k127_6149365_0	700598.Niako_0959	9.809e-56	200.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_615194_0	1267211.KI669560_gene2736	1.288e-194	610.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CSH2_k127_6153173_0	929556.Solca_0260	1.103e-193	617.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRAB@117747|Sphingobacteriia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,HTH_18,MacB_PCD
CSH2_k127_6153173_1	929556.Solca_0258	4.484e-31	123.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CSH2_k127_6160896_1	925409.KI911562_gene201	1.834e-22	99.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CSH2_k127_6160896_0	700598.Niako_7075	1.305e-137	447.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CSH2_k127_6164477_0	1122176.KB903554_gene3961	7.705e-167	537.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IR7S@117747|Sphingobacteriia	976|Bacteroidetes	G	Fibronectin type III-like domain	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_6171281_2	398767.Glov_2665	1.267e-22	100.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42T96@68525|delta/epsilon subdivisions,2X5B8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HhH-GPD superfamily base excision DNA repair protein	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CSH2_k127_6171281_1	925409.KI911562_gene444	8.949e-143	465.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1IPFH@117747|Sphingobacteriia	976|Bacteroidetes	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
CSH2_k127_6171281_0	1122605.KB893646_gene110	9.059e-209	654.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
CSH2_k127_6171281_3	1392488.JHZY01000004_gene2420	0.0004362	43.0	2A3FH@1|root,30RY7@2|Bacteria,4PE4E@976|Bacteroidetes,1IEJT@117743|Flavobacteriia,2XKDS@283735|Leeuwenhoekiella	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6172740_0	1123248.KB893386_gene1983	3.341e-194	619.0	COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,1IV8M@117747|Sphingobacteriia	976|Bacteroidetes	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CSH2_k127_6175122_0	700598.Niako_5754	4.25e-152	494.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IR4K@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CSH2_k127_6175122_1	700598.Niako_5755	1.919e-129	421.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1IQCH@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CSH2_k127_617737_0	925409.KI911562_gene2671	2.653e-244	766.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CSH2_k127_617737_1	925409.KI911562_gene2672	1.601e-52	187.0	COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,1IQKP@117747|Sphingobacteriia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CSH2_k127_6179379_5	925409.KI911562_gene1446	3.963e-42	156.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CSH2_k127_6179379_2	700598.Niako_5707	9.318e-93	317.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1INPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
CSH2_k127_6179379_0	925409.KI911562_gene1444	7.293e-143	458.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1IPAD@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CSH2_k127_6179379_1	1123248.KB893385_gene4877	2.141e-116	387.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,1IPJE@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_2	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
CSH2_k127_6179379_4	700598.Niako_5711	3.126e-42	158.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1ISV5@117747|Sphingobacteriia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CSH2_k127_6179379_3	1123248.KB893385_gene4879	8.665e-50	185.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1IQ58@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CSH2_k127_6183840_4	1267211.KI669560_gene1431	1.765e-13	71.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1IYC2@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CSH2_k127_6183840_1	925409.KI911562_gene2630	2.296e-69	240.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,1ISD6@117747|Sphingobacteriia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CSH2_k127_6183840_0	1123248.KB893359_gene2142	7.895e-135	441.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
CSH2_k127_6183840_2	925409.KI911562_gene2628	1.507e-39	151.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1ISTX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
CSH2_k127_6183840_3	925409.KI911562_gene2627	1.709e-24	107.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6187254_0	485918.Cpin_4703	7.486e-75	263.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1IV9F@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CSH2_k127_6187254_4	545693.BMQ_1125	4.496e-05	55.0	COG2244@1|root,COG2244@2|Bacteria,1V929@1239|Firmicutes,4HKDX@91061|Bacilli,1ZF2G@1386|Bacillus	91061|Bacilli	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CSH2_k127_6187254_1	877455.Metbo_0725	4.996e-48	183.0	COG0463@1|root,arCOG01381@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
CSH2_k127_6187254_2	309799.DICTH_0152	7.133e-42	162.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPR_16,TPR_2,TPR_8
CSH2_k127_6187254_3	1306174.JODP01000001_gene5252	3.416e-07	62.0	COG0438@1|root,COG0438@2|Bacteria,2IRB6@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4
CSH2_k127_6190044_0	700598.Niako_7358	1.284e-192	606.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1IPUW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CSH2_k127_6190044_2	700598.Niako_5643	9.065e-53	189.0	COG0454@1|root,COG0456@2|Bacteria,4NWTW@976|Bacteroidetes,1IZJT@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CSH2_k127_6190044_1	945713.IALB_2233	2.366e-74	261.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
CSH2_k127_6194797_1	700598.Niako_6852	2.143e-69	237.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1IPP4@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CSH2_k127_6194797_0	1123248.KB893359_gene2113	6.373e-243	769.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CSH2_k127_6194797_2	700598.Niako_6854	4.079e-56	200.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1IP8A@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_6195419_0	700598.Niako_4423	2.593e-155	497.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_6199835_0	1267211.KI669560_gene1380	6.118e-133	427.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CSH2_k127_6199835_1	929713.NIASO_06515	3.92e-32	126.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,1IP0F@117747|Sphingobacteriia	976|Bacteroidetes	S	HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CSH2_k127_6205906_0	445961.IW15_19590	1.19e-95	324.0	COG4313@1|root,COG4313@2|Bacteria,4NW4N@976|Bacteroidetes,1I60R@117743|Flavobacteriia	976|Bacteroidetes	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CSH2_k127_6207405_0	1123248.KB893319_gene4058	1.389e-106	354.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CSH2_k127_6211782_2	1123248.KB893323_gene1617	2.411e-21	100.0	2DKFZ@1|root,309D6@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
CSH2_k127_6211782_0	1239962.C943_04260	8.401e-48	177.0	COG3610@1|root,COG3610@2|Bacteria,4NP5R@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
CSH2_k127_6211782_1	1239962.C943_04259	1.674e-46	170.0	COG2966@1|root,COG2966@2|Bacteria,4NIU3@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG2966 conserved	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
CSH2_k127_6213507_1	1191523.MROS_2264	4.152e-60	211.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porG	-	1.2.7.3,1.2.7.7	ko:K00177,ko:K00187	ko00020,ko00280,ko00720,ko01100,ko01120,ko01200,map00020,map00280,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197,R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CSH2_k127_6213507_0	945713.IALB_0273	1.782e-108	357.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CSH2_k127_6213507_2	945713.IALB_0272	1.79e-15	76.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CSH2_k127_6217910_1	1123248.KB893314_gene3437	1.932e-60	212.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CSH2_k127_6217910_0	700598.Niako_5147	5.699e-190	596.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IUYE@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CSH2_k127_6217910_2	1033734.CAET01000079_gene3677	6.946e-05	49.0	2DIA4@1|root,302HW@2|Bacteria,1U5Y3@1239|Firmicutes,4IM9X@91061|Bacilli,1ZJJZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6220020_1	1123248.KB893316_gene4543	2.469e-89	297.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1IQIF@117747|Sphingobacteriia	976|Bacteroidetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CSH2_k127_6220020_0	700598.Niako_0358	6.729e-101	331.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1INY5@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CSH2_k127_6226402_0	714943.Mucpa_5139	9.734e-175	556.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,1IPJ3@117747|Sphingobacteriia	976|Bacteroidetes	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CSH2_k127_6226402_1	1123248.KB893324_gene1764	2.187e-06	55.0	28ICP@1|root,314Q6@2|Bacteria,4PIZD@976|Bacteroidetes,1IZ0B@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6232012_0	929562.Emtol_2608	2.125e-178	563.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,47KXT@768503|Cytophagia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CSH2_k127_6232012_1	714943.Mucpa_1617	6.737e-62	221.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1IS2C@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
CSH2_k127_6240504_1	929562.Emtol_1980	9.152e-56	199.0	COG0457@1|root,COG0457@2|Bacteria,4PN8J@976|Bacteroidetes,47YES@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CSH2_k127_6240504_0	1492738.FEM21_26580	1.064e-142	462.0	COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1HZT9@117743|Flavobacteriia,2NVAZ@237|Flavobacterium	976|Bacteroidetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CSH2_k127_6241623_0	485918.Cpin_2717	4.668e-149	476.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1IQEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CSH2_k127_6241743_0	1123248.KB893329_gene4492	3.541e-202	638.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1IQJQ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CSH2_k127_6241743_1	485918.Cpin_6982	4.462e-20	90.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1IR5B@117747|Sphingobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CSH2_k127_6253112_0	1123248.KB893331_gene3797	2.082e-275	864.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPEH@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CSH2_k127_6253112_1	1122605.KB893626_gene2785	7.521e-120	391.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CSH2_k127_6254460_0	925409.KI911562_gene1256	1.773e-191	606.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1IP91@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_6255838_0	925409.KI911562_gene2961	5.834e-137	451.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1ISVQ@117747|Sphingobacteriia	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
CSH2_k127_6265326_0	929556.Solca_1036	4.708e-54	208.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1IPSE@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
CSH2_k127_6273088_0	485918.Cpin_1273	6.981e-185	584.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1IPH5@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
CSH2_k127_6273088_1	925409.KI911562_gene1231	2.763e-40	157.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CSH2_k127_627469_0	1123248.KB893317_gene4296	8.343e-65	225.0	COG1629@1|root,COG4771@2|Bacteria,4PMEH@976|Bacteroidetes,1J0ZJ@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
CSH2_k127_627469_1	1166018.FAES_4816	1.599e-21	100.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47JGM@768503|Cytophagia	976|Bacteroidetes	G	COGs COG2133 Glucose sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CSH2_k127_6286839_1	700598.Niako_0937	1.592e-57	204.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1INQX@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CSH2_k127_6286839_0	1239962.C943_01040	1.145e-133	438.0	COG2207@1|root,COG2207@2|Bacteria,4NWRQ@976|Bacteroidetes,47XEP@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CSH2_k127_6286839_2	1239962.C943_01039	2.555e-36	139.0	COG2015@1|root,COG2015@2|Bacteria,4NJE2@976|Bacteroidetes	976|Bacteroidetes	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
CSH2_k127_6293689_0	1267211.KI669560_gene1788	9.584e-47	174.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1IPIG@117747|Sphingobacteriia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CSH2_k127_6293689_1	1380600.AUYN01000009_gene1971	1.247e-05	53.0	COG5649@1|root,COG5649@2|Bacteria,4NSZR@976|Bacteroidetes,1I4H5@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CSH2_k127_6300867_2	700598.Niako_6461	3.598e-77	263.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6300867_1	700598.Niako_5811	1.716e-135	439.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
CSH2_k127_6300867_3	573061.Clocel_1966	2.776e-39	169.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CSH2_k127_6300867_0	153721.MYP_3853	7.047e-223	720.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CSH2_k127_6301029_0	1189612.A33Q_0629	3.356e-86	291.0	COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
CSH2_k127_6304202_5	1123248.KB893318_gene4149	5.706e-54	192.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1IPT2@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CSH2_k127_6304202_0	700598.Niako_5482	3.912e-148	484.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
CSH2_k127_6304202_3	700598.Niako_5507	2.117e-82	286.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,1IP5H@117747|Sphingobacteriia	976|Bacteroidetes	NU	COG1705 Muramidase (flagellum-specific)	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
CSH2_k127_6304202_4	1267211.KI669560_gene1358	6.343e-73	250.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1ISTD@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CSH2_k127_6304202_2	1267211.KI669560_gene1357	2.947e-120	408.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
CSH2_k127_6304202_1	700598.Niako_5504	1.145e-122	396.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CSH2_k127_6313382_0	925409.KI911562_gene2510	2.269e-110	358.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CSH2_k127_6313382_1	1270196.JCKI01000003_gene1889	7.471e-40	153.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
CSH2_k127_6313382_2	762903.Pedsa_0928	1.353e-19	91.0	2DXSD@1|root,346A9@2|Bacteria,4P5K0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6313382_3	1267211.KI669560_gene1599	6.773e-15	74.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CSH2_k127_631877_0	1122179.KB890421_gene2565	5.328e-24	106.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4PM4Q@976|Bacteroidetes	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CSH2_k127_631877_1	1216932.CM240_0473	1.436e-10	72.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
CSH2_k127_6321980_0	1123248.KB893314_gene3644	9.06e-141	456.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQZ4@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_6326640_1	1358423.N180_18910	8.825e-08	55.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IW0A@117747|Sphingobacteriia	976|Bacteroidetes	I	transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CSH2_k127_6326640_0	714943.Mucpa_1920	9.887e-125	403.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CSH2_k127_6333840_0	485918.Cpin_1955	3.464e-123	399.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
CSH2_k127_6333840_1	1123248.KB893323_gene1654	2.219e-70	242.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
CSH2_k127_6334549_3	1122605.KB893632_gene4390	1.315e-36	141.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CSH2_k127_6334549_1	714943.Mucpa_1493	6.193e-90	304.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1IP44@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CSH2_k127_6334549_2	1122605.KB893632_gene4338	6.958e-64	225.0	COG2860@1|root,COG2860@2|Bacteria,4NEXS@976|Bacteroidetes,1ISGW@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
CSH2_k127_6334549_0	1267211.KI669560_gene2549	1.359e-154	491.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_6338102_1	880070.Cycma_4553	8.361e-74	252.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,4NM18@976|Bacteroidetes,47XKA@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
CSH2_k127_6338102_0	760192.Halhy_6513	0.0	1692.0	COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CSH2_k127_6341633_1	925409.KI911562_gene17	5.499e-19	91.0	COG3206@1|root,COG3206@2|Bacteria,4P3QF@976|Bacteroidetes	976|Bacteroidetes	M	Domain of unknown function (DUF4407)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4407
CSH2_k127_6341633_0	1123248.KB893322_gene578	2.484e-249	780.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1IQZ1@117747|Sphingobacteriia	976|Bacteroidetes	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CSH2_k127_634277_2	700598.Niako_6480	1.09e-48	179.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CSH2_k127_634277_0	1267211.KI669560_gene118	2.447e-88	294.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ITGM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
CSH2_k127_634277_3	880070.Cycma_0365	4.069e-41	154.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CSH2_k127_634277_1	1123277.KB893195_gene5660	1.205e-67	233.0	COG2080@1|root,COG2080@2|Bacteria,4NMVV@976|Bacteroidetes,47Q3P@768503|Cytophagia	976|Bacteroidetes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CSH2_k127_634277_4	509635.N824_00495	0.0001025	46.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IR1H@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CSH2_k127_6343637_0	749222.Nitsa_1999	1.504e-161	516.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CSH2_k127_6343637_1	1123248.KB893348_gene85	2.454e-61	226.0	COG0438@1|root,COG0438@2|Bacteria,4NF7J@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_6343637_2	1267211.KI669560_gene804	2.241e-34	132.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,1IS5U@117747|Sphingobacteriia	976|Bacteroidetes	K	MerR family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
CSH2_k127_6345203_0	1239962.C943_02243	6.885e-188	589.0	COG4775@1|root,COG4775@2|Bacteria,4NHNW@976|Bacteroidetes,47QHX@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CSH2_k127_6345203_1	1239962.C943_01045	7.444e-117	380.0	COG2207@1|root,COG2207@2|Bacteria,4NWRQ@976|Bacteroidetes,47XEP@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CSH2_k127_6345207_0	1121899.Q764_07535	8.023e-91	312.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia,2NUFJ@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6346013_1	700598.Niako_6869	4.259e-67	231.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IP88@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CSH2_k127_6346013_0	485918.Cpin_0195	1.233e-113	372.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CSH2_k127_6349923_0	700598.Niako_5549	7.737e-145	465.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1IQSD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CSH2_k127_6350856_0	1123248.KB893326_gene1316	1.13e-137	451.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1IQWN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
CSH2_k127_6350856_1	700598.Niako_0407	3.655e-50	182.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1IPTV@117747|Sphingobacteriia	976|Bacteroidetes	G	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CSH2_k127_635663_0	1123248.KB893315_gene3124	4.269e-102	356.0	COG0457@1|root,COG1729@1|root,COG3147@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3147@2|Bacteria,4NDV9@976|Bacteroidetes,1IQQP@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
CSH2_k127_6357899_1	760192.Halhy_2537	2.142e-16	79.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
CSH2_k127_6357899_0	700598.Niako_4610	4.662e-313	966.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CSH2_k127_6362887_0	1121957.ATVL01000006_gene2654	2.929e-37	144.0	2BQG9@1|root,32JBP@2|Bacteria,4NREU@976|Bacteroidetes,47URQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6368721_1	1239962.C943_01704	4.419e-19	91.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
CSH2_k127_6368721_0	1189612.A33Q_1181	2.05e-50	192.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
CSH2_k127_6371947_3	1121904.ARBP01000007_gene3061	4.003e-16	79.0	COG0664@1|root,COG0664@2|Bacteria,4NM5E@976|Bacteroidetes,47R9U@768503|Cytophagia	976|Bacteroidetes	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CSH2_k127_6371947_0	526227.Mesil_2803	7.041e-132	430.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
CSH2_k127_6371947_2	1123248.KB893326_gene1488	9.851e-49	179.0	COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional repressor, CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CSH2_k127_6371947_1	925409.KI911562_gene2432	6.264e-70	257.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,1IPFV@117747|Sphingobacteriia	976|Bacteroidetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CSH2_k127_6374530_3	1267211.KI669560_gene1629	5.98e-05	46.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1IRVC@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6374530_0	1121896.JMLU01000024_gene2527	1.187e-71	246.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia,2NV62@237|Flavobacterium	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CSH2_k127_6374530_2	1267211.KI669560_gene1631	3.415e-44	163.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes,1J0FW@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CSH2_k127_6374530_1	929713.NIASO_09225	3.888e-65	226.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1IPGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
CSH2_k127_6376031_0	1123248.KB893316_gene4610	1.605e-123	399.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1IYQQ@117747|Sphingobacteriia	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
CSH2_k127_6376031_1	700598.Niako_3669	7.696e-96	321.0	COG1502@1|root,COG1502@2|Bacteria,4P0CZ@976|Bacteroidetes,1J0D9@117747|Sphingobacteriia	976|Bacteroidetes	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CSH2_k127_6386441_0	929713.NIASO_01615	9.989e-75	262.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,1ISX6@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CSH2_k127_6386441_1	1123248.KB893321_gene559	1.077e-66	237.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,1IYJZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CSH2_k127_638919_1	1267211.KI669560_gene1438	1.671e-104	343.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
CSH2_k127_638919_0	929713.NIASO_08770	3.189e-118	384.0	COG0297@1|root,COG0297@2|Bacteria,4NET6@976|Bacteroidetes,1IQCB@117747|Sphingobacteriia	976|Bacteroidetes	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CSH2_k127_6401301_1	1296415.JACC01000010_gene2149	1.605e-61	220.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CSH2_k127_6401301_0	313606.M23134_01967	1.642e-63	224.0	COG2124@1|root,COG2124@2|Bacteria,4NTT4@976|Bacteroidetes,47R85@768503|Cytophagia	976|Bacteroidetes	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CSH2_k127_6404893_1	700598.Niako_5241	5.025e-97	329.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,1IQ0I@117747|Sphingobacteriia	976|Bacteroidetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,ROK
CSH2_k127_6404893_0	700598.Niako_3960	0.0	1070.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,1IPSI@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
CSH2_k127_6404893_2	929703.KE386491_gene113	2.598e-38	148.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CSH2_k127_6411903_1	925409.KI911562_gene2304	1.625e-43	160.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IPDN@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_6411903_0	1123277.KB893228_gene2159	5.241e-93	309.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47KSM@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_6413829_2	760192.Halhy_1216	1.118e-15	76.0	COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,1INXZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.8	ko:K12658	ko00330,map00330	-	R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
CSH2_k127_6413829_1	929562.Emtol_2436	1.297e-28	117.0	COG2350@1|root,COG2350@2|Bacteria,4NT2N@976|Bacteroidetes,47RBM@768503|Cytophagia	976|Bacteroidetes	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
CSH2_k127_6413829_0	1267211.KI669560_gene2284	4.45e-105	349.0	COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,1IPI3@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
CSH2_k127_641563_0	1123277.KB893203_gene6259	9.468e-189	595.0	COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,47N41@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M20/M25/M40	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CSH2_k127_641563_2	1341181.FLJC2902T_28550	2.054e-22	108.0	2FD2D@1|root,3454V@2|Bacteria,4P66V@976|Bacteroidetes,1IDWK@117743|Flavobacteriia,2NZD3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_642466_0	485918.Cpin_0676	8.809e-102	341.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1IQ8K@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YicC-like family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CSH2_k127_642466_2	509635.N824_07530	1.134e-25	123.0	28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,1IS7W@117747|Sphingobacteriia	976|Bacteroidetes	S	SusE outer membrane protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
CSH2_k127_6427056_0	925409.KI911562_gene1590	3.001e-204	651.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_6427556_0	485918.Cpin_0411	1.047e-179	568.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1IPE0@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CSH2_k127_643198_1	700598.Niako_1511	2.262e-24	103.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1IQ1X@117747|Sphingobacteriia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CSH2_k127_643198_0	1267211.KI669560_gene2005	4.779e-58	210.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
CSH2_k127_6459760_0	1267211.KI669560_gene2228	2.691e-98	330.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CSH2_k127_6459760_1	700598.Niako_2927	1.26e-38	147.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1ISRE@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CSH2_k127_6478675_2	929713.NIASO_11630	7.886e-102	334.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
CSH2_k127_6478675_0	700598.Niako_7069	1.527e-156	500.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1IR49@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CSH2_k127_6478675_3	1218108.KB908293_gene1340	1.74e-20	93.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CSH2_k127_6478675_1	1123248.KB893381_gene1033	5.1e-110	359.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
CSH2_k127_6492043_0	1123248.KB893329_gene4484	3.753e-220	695.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
CSH2_k127_6492043_1	1123248.KB893329_gene4483	1.771e-05	48.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,1ITPF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6498370_0	1267211.KI669560_gene407	3.63e-135	438.0	COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1IV0D@117747|Sphingobacteriia	976|Bacteroidetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CSH2_k127_650720_1	1237149.C900_03832	1.181e-07	54.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CSH2_k127_650720_0	700598.Niako_2615	1.576e-105	352.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1IPT7@117747|Sphingobacteriia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
CSH2_k127_6508549_0	1122605.KB893625_gene1800	9.787e-141	457.0	COG4870@1|root,COG4870@2|Bacteria,4NS9R@976|Bacteroidetes,1IWTU@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_C1
CSH2_k127_6516460_0	1279009.ADICEAN_03081	4.72e-62	226.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
CSH2_k127_65216_1	925409.KI911562_gene2343	1.806e-66	231.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CSH2_k127_65216_0	1267211.KI669560_gene1940	2.955e-127	408.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
CSH2_k127_6536633_0	1123248.KB893370_gene5002	1.412e-72	252.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1IP2P@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CSH2_k127_6536633_1	1267211.KI669560_gene1655	1.018e-68	245.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1IPC8@117747|Sphingobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CSH2_k127_6536633_2	700598.Niako_1185	1.621e-53	195.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CSH2_k127_6542857_0	929562.Emtol_0758	2.516e-100	339.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CSH2_k127_6550481_2	1267211.KI669560_gene46	3.367e-53	191.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1ISSQ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6550481_3	1121904.ARBP01000001_gene5889	1.287e-07	57.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
CSH2_k127_6550481_1	700598.Niako_6593	4.751e-123	399.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CSH2_k127_6550481_0	700598.Niako_6594	1.243e-261	822.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1IR22@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CSH2_k127_6553556_0	925409.KI911562_gene315	6.356e-136	434.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1IP9V@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CSH2_k127_6553556_1	1267211.KI669560_gene2860	2.181e-20	95.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU2I@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CSH2_k127_6553556_2	700598.Niako_6652	1.996e-05	51.0	2DQSK@1|root,338E4@2|Bacteria,4NX60@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6560956_0	714943.Mucpa_4399	5.258e-125	409.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IQRG@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CSH2_k127_656100_0	509635.N824_23255	6.597e-112	363.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,1IPU8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CSH2_k127_656100_1	485918.Cpin_7005	3.691e-58	215.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1INVB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Aminoglycoside phosphotransferase	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
CSH2_k127_656100_2	1305737.JAFX01000001_gene3351	4.66e-24	105.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47MGE@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
CSH2_k127_6563319_1	929556.Solca_2027	6.674e-53	187.0	COG1247@1|root,COG1247@2|Bacteria,4PM4N@976|Bacteroidetes,1ISGA@117747|Sphingobacteriia	976|Bacteroidetes	M	Gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_6563319_0	1123248.KB893322_gene600	9.602e-133	429.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1IQ02@117747|Sphingobacteriia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CSH2_k127_6563319_2	762903.Pedsa_2884	1.026e-06	50.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CSH2_k127_6570519_0	1123248.KB893317_gene4296	5.802e-153	497.0	COG1629@1|root,COG4771@2|Bacteria,4PMEH@976|Bacteroidetes,1J0ZJ@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
CSH2_k127_6570519_1	929713.NIASO_01760	4.717e-91	303.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CSH2_k127_6577393_1	1249975.JQLP01000005_gene1354	4.27e-42	160.0	299YT@1|root,2ZX0H@2|Bacteria,4NP1B@976|Bacteroidetes,1I3KF@117743|Flavobacteriia,2P6R3@244698|Gillisia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
CSH2_k127_6577393_0	1267211.KI669560_gene563	5.956e-108	352.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1IQ4T@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
CSH2_k127_6583769_0	743722.Sph21_3373	1.265e-144	467.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IRCM@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
CSH2_k127_6593706_1	1123248.KB893316_gene4628	1.099e-45	169.0	COG3536@1|root,COG3536@2|Bacteria,4PKQ9@976|Bacteroidetes,1IRMG@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6593706_0	1123248.KB893316_gene4629	3.667e-75	260.0	COG4372@1|root,COG4372@2|Bacteria,4NTCH@976|Bacteroidetes,1J0SD@117747|Sphingobacteriia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6594279_3	1123278.KB893387_gene4311	8.165e-36	140.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_6594279_2	1124780.ANNU01000006_gene2817	1.208e-48	176.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
CSH2_k127_6594279_1	1123248.KB893348_gene200	4.113e-58	206.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1ISDN@117747|Sphingobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
CSH2_k127_6594279_4	1267211.KI669560_gene347	1.546e-05	57.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,Cadherin-like,Calx-beta,Flg_new
CSH2_k127_6594279_0	761193.Runsl_1994	7.91e-94	312.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JJV@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CSH2_k127_6594459_1	1123248.KB893319_gene4064	1.104e-43	169.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CSH2_k127_6594459_0	29581.BW37_01372	8.156e-124	413.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,4725W@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CSH2_k127_6596577_0	29875.EHK19202	4.726e-15	87.0	KOG0272@1|root,KOG0272@2759|Eukaryota,3AFR9@33154|Opisthokonta,3Q43U@4751|Fungi,3RM91@4890|Ascomycota,21RI5@147550|Sordariomycetes,3TUU9@5125|Hypocreales	4751|Fungi	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,NACHT_N,WD40
CSH2_k127_6601957_1	1122605.KB893626_gene2543	3.241e-43	160.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CSH2_k127_6601957_0	1122605.KB893646_gene227	1.109e-103	344.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CSH2_k127_6601957_2	700598.Niako_6937	7.406e-23	101.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1IUJM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
CSH2_k127_6602201_0	700598.Niako_4416	1.207e-98	328.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CSH2_k127_6602201_1	485918.Cpin_2331	9.097e-64	228.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CSH2_k127_6604051_1	925409.KI911562_gene617	3.874e-73	250.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1IQ5S@117747|Sphingobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
CSH2_k127_6604051_0	925409.KI911562_gene889	2.27e-112	369.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes	976|Bacteroidetes	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CSH2_k127_66054_1	700598.Niako_4351	3.557e-19	92.0	COG0484@1|root,COG0484@2|Bacteria,4P77W@976|Bacteroidetes	976|Bacteroidetes	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CSH2_k127_66054_0	700598.Niako_2452	1.991e-76	266.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1INWN@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_6609963_0	1121875.KB907549_gene2024	9.901e-42	155.0	COG2303@1|root,COG2303@2|Bacteria,4NMEP@976|Bacteroidetes,1IA7R@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
CSH2_k127_6609963_1	313606.M23134_01176	2.347e-36	145.0	COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CSH2_k127_6610561_1	709991.Odosp_1604	1.971e-09	67.0	COG3187@1|root,COG3187@2|Bacteria,4NRFE@976|Bacteroidetes,2FQEM@200643|Bacteroidia	976|Bacteroidetes	O	COG3187 Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	META
CSH2_k127_6610561_0	1189612.A33Q_2739	5.243e-94	315.0	COG0622@1|root,COG0622@2|Bacteria,4NGFH@976|Bacteroidetes	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CSH2_k127_66180_0	925409.KI911562_gene1532	5.908e-55	199.0	2E373@1|root,32Y6V@2|Bacteria,4NWZF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6618991_0	700598.Niako_5083	1.01e-134	441.0	COG0793@1|root,COG0793@2|Bacteria,4NFKJ@976|Bacteroidetes,1IS75@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41
CSH2_k127_6618991_1	172045.KS04_07890	5.986e-09	59.0	COG4413@1|root,COG4413@2|Bacteria,4NHK4@976|Bacteroidetes,1I1WG@117743|Flavobacteriia	976|Bacteroidetes	E	urea transporter	-	-	-	ko:K08717	-	-	-	-	ko00000,ko02000	1.A.28.2	-	-	UT
CSH2_k127_6630402_0	1123508.JH636444_gene5358	2.059e-123	406.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CSH2_k127_6649387_0	760192.Halhy_4219	1.987e-242	766.0	COG1680@1|root,COG3653@1|root,COG1680@2|Bacteria,COG3653@2|Bacteria,4NI1Z@976|Bacteroidetes,1J19H@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Beta-lactamase
CSH2_k127_6654067_2	925409.KI911562_gene2937	1.267e-15	79.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CSH2_k127_6654067_1	485917.Phep_1934	6.907e-25	114.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1IU8K@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CSH2_k127_6654067_0	925409.KI911562_gene2698	9.115e-95	314.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CSH2_k127_6658035_0	1123248.KB893315_gene3191	2.498e-247	766.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1INUN@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_6661968_0	1189612.A33Q_0629	0.0	1099.0	COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia	976|Bacteroidetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
CSH2_k127_6664591_1	700598.Niako_5253	3.085e-13	70.0	COG1723@1|root,COG1723@2|Bacteria,4NFED@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
CSH2_k127_6664591_0	929703.KE386491_gene3058	4.232e-105	352.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47K0G@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_6666392_1	641526.ADIWIN_3133	1.197e-57	211.0	COG0657@1|root,COG0657@2|Bacteria,4NFTX@976|Bacteroidetes,1I0SN@117743|Flavobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CSH2_k127_6666392_0	1123248.KB893330_gene398	5.262e-96	320.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CSH2_k127_6670871_2	925409.KI911562_gene2391	3.885e-15	76.0	2DMQT@1|root,32T2H@2|Bacteria,4NN19@976|Bacteroidetes,1ISWP@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
CSH2_k127_6670871_1	1296416.JACB01000029_gene4201	2.825e-102	336.0	COG1652@1|root,COG1652@2|Bacteria,4NJV3@976|Bacteroidetes,1I1VG@117743|Flavobacteriia,2YJMH@290174|Aquimarina	976|Bacteroidetes	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6670871_0	1296416.JACB01000029_gene4200	1.181e-186	595.0	COG3501@1|root,COG3501@2|Bacteria,4NFPB@976|Bacteroidetes,1HZN7@117743|Flavobacteriia,2YM49@290174|Aquimarina	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
CSH2_k127_6673645_2	1279009.ADICEAN_02543	4.16e-49	183.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CSH2_k127_6673645_0	1453500.AT05_01305	1.087e-55	208.0	28ICX@1|root,2Z9XD@2|Bacteria,4NIE3@976|Bacteroidetes,1IJ2N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6673645_1	925409.KI911562_gene450	1.428e-53	191.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1ISQF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6681302_2	1353529.M899_2375	4.015e-08	64.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CSH2_k127_6681302_1	926550.CLDAP_07810	1.244e-11	76.0	29YB7@1|root,30K5H@2|Bacteria,2G83K@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6681302_0	925409.KI911562_gene306	1.999e-22	102.0	COG1289@1|root,COG1289@2|Bacteria,4NG4J@976|Bacteroidetes,1IPER@117747|Sphingobacteriia	976|Bacteroidetes	S	FUSC-like inner membrane protein yccS	yccS	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
CSH2_k127_6684450_1	1450525.JATV01000005_gene455	4.805e-34	133.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia,2NSWR@237|Flavobacterium	976|Bacteroidetes	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
CSH2_k127_6684450_0	1123248.KB893323_gene1558	3.99e-61	214.0	2B1RZ@1|root,31U7Q@2|Bacteria,4NR0B@976|Bacteroidetes,1IYX1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6698791_1	760192.Halhy_4972	3.103e-29	119.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1IPI2@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_6698791_2	1121904.ARBP01000005_gene4823	1.059e-15	79.0	28MAS@1|root,2ZAPE@2|Bacteria,4NJ31@976|Bacteroidetes,47TP8@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CSH2_k127_670337_0	1267533.KB906736_gene1284	9.078e-41	161.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CSH2_k127_6706012_0	1267211.KI669560_gene348	1.714e-122	403.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVNR@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_670684_1	531844.FIC_00210	3.288e-56	204.0	COG2985@1|root,COG2985@2|Bacteria,4NEBW@976|Bacteroidetes,1HZIV@117743|Flavobacteriia	976|Bacteroidetes	U	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
CSH2_k127_670684_0	760192.Halhy_1807	1.931e-112	366.0	COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1IPQ0@117747|Sphingobacteriia	976|Bacteroidetes	O	AhpC TSA family	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CSH2_k127_670684_2	1233950.IW22_11110	3.952e-46	169.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1I1Z9@117743|Flavobacteriia,3ZRMD@59732|Chryseobacterium	976|Bacteroidetes	K	Rrf2 family transcriptional regulator	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CSH2_k127_670684_3	1267211.KI669560_gene620	3.646e-34	135.0	COG2146@1|root,COG2146@2|Bacteria,4NV9E@976|Bacteroidetes,1ITVU@117747|Sphingobacteriia	976|Bacteroidetes	P	Rieske (2Fe-2S) domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske,Rieske_2
CSH2_k127_670684_4	1123277.KB893173_gene1609	1.457e-09	65.0	COG1820@1|root,COG1820@2|Bacteria,4NJ35@976|Bacteroidetes,47KJ5@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CSH2_k127_6715911_0	929556.Solca_2194	1.8e-76	271.0	COG4942@1|root,COG4942@2|Bacteria,4P0BC@976|Bacteroidetes,1IXE6@117747|Sphingobacteriia	976|Bacteroidetes	D	Protein of unknown function (DUF3375)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3375
CSH2_k127_6716505_4	1122176.KB903540_gene54	0.0008195	42.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1INW8@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
CSH2_k127_6716505_0	925409.KI911562_gene1811	8.707e-118	381.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1IP8P@117747|Sphingobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CSH2_k127_6716505_1	404589.Anae109_0378	2.217e-50	189.0	COG3306@1|root,COG3306@2|Bacteria,1NGNU@1224|Proteobacteria	1224|Proteobacteria	M	PFAM glycosyl transferase family 25	-	-	-	ko:K07270	-	-	-	-	ko00000	-	GT25	-	Glyco_transf_25
CSH2_k127_6716505_2	700598.Niako_6540	6.005e-36	144.0	COG4123@1|root,COG4123@2|Bacteria,4NQKD@976|Bacteroidetes	976|Bacteroidetes	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CSH2_k127_6717837_0	203119.Cthe_0640	1.149e-43	177.0	COG5434@1|root,COG5434@2|Bacteria,1UQXS@1239|Firmicutes,258QV@186801|Clostridia,3WNDQ@541000|Ruminococcaceae	186801|Clostridia	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Pectate_lyase_3
CSH2_k127_6723799_0	925409.KI911562_gene2056	1.114e-247	767.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CSH2_k127_6731961_0	1123248.KB893322_gene595	1.504e-136	443.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1INS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CSH2_k127_673382_0	1121904.ARBP01000017_gene5136	1.738e-183	576.0	COG5285@1|root,COG5285@2|Bacteria,4NG3B@976|Bacteroidetes,47N28@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CSH2_k127_673382_1	700598.Niako_4399	2.611e-75	256.0	COG4977@1|root,COG4977@2|Bacteria,4PKR2@976|Bacteroidetes,1J0NT@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CSH2_k127_6737579_1	929713.NIASO_11650	9.405e-72	243.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1IS1Q@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CSH2_k127_6737579_2	1331660.L313_0106	5.821e-23	104.0	COG3015@1|root,COG3015@2|Bacteria,1N97X@1224|Proteobacteria,1SEMN@1236|Gammaproteobacteria,3NNDC@468|Moraxellaceae	1236|Gammaproteobacteria	MP	NlpE N-terminal domain	nlpE	-	-	-	-	-	-	-	-	-	-	-	NlpE
CSH2_k127_6737579_0	700598.Niako_7067	7.836e-179	563.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CSH2_k127_6744356_0	1267211.KI669560_gene1023	1.745e-249	776.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_6744356_1	1267211.KI669560_gene1022	5.338e-109	358.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes	976|Bacteroidetes	M	RagB, SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_6744613_2	700598.Niako_3733	1.992e-61	219.0	COG0300@1|root,COG0300@2|Bacteria,4NK81@976|Bacteroidetes,1ISB6@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_6744613_0	313606.M23134_01996	7.249e-110	368.0	COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_6744613_1	1267211.KI669560_gene1544	1.975e-96	323.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	MA20_03510	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_674761_1	1122605.KB893626_gene2546	2.501e-33	134.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CSH2_k127_674761_0	1267211.KI669560_gene2793	1.576e-70	246.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1ISJU@117747|Sphingobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CSH2_k127_6756074_1	700598.Niako_6542	1.112e-67	238.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1ISZE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
CSH2_k127_6756074_0	1123248.KB893348_gene340	1.118e-98	331.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1IQP5@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_675642_0	1121875.KB907552_gene306	2.516e-90	305.0	COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,1HZEI@117743|Flavobacteriia	976|Bacteroidetes	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CSH2_k127_675642_1	471854.Dfer_5686	3.455e-05	55.0	COG2143@1|root,COG2143@2|Bacteria,4PJZE@976|Bacteroidetes,47Q3S@768503|Cytophagia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_676069_0	1122621.ATZA01000008_gene921	4.495e-173	559.0	2BVKK@1|root,2Z8PC@2|Bacteria,4NF9X@976|Bacteroidetes,1ISAS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6765204_0	700598.Niako_6983	2.816e-116	385.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,1IQMJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
CSH2_k127_6765217_0	929556.Solca_2701	8.51e-81	277.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CSH2_k127_6765217_1	1166018.FAES_5034	4.846e-32	127.0	COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,47P0A@768503|Cytophagia	976|Bacteroidetes	F	PFAM RagB SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_678686_1	1267211.KI669560_gene925	1.806e-55	198.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1IQ95@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase, family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_678686_0	1408813.AYMG01000014_gene1509	1.223e-99	332.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,1IQD0@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
CSH2_k127_678693_0	1120965.AUBV01000003_gene494	2.026e-78	266.0	COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,47NB9@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CSH2_k127_678693_2	700598.Niako_5780	4.038e-05	53.0	2ECA3@1|root,3368F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_678693_1	925409.KI911562_gene1504	5.404e-33	138.0	COG4585@1|root,COG4585@2|Bacteria,4NM9X@976|Bacteroidetes,1ISCC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CSH2_k127_678782_0	880071.Fleli_2790	4.226e-118	396.0	COG1409@1|root,COG1409@2|Bacteria,4P3GR@976|Bacteroidetes	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CSH2_k127_678782_2	313606.M23134_08300	1.366e-79	291.0	COG2114@1|root,COG2208@1|root,COG2114@2|Bacteria,COG2208@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,Reg_prop,Response_reg,Y_Y_Y
CSH2_k127_678782_4	1094466.KQS_10955	4.094e-24	119.0	COG5295@1|root,COG5295@2|Bacteria,4NN21@976|Bacteroidetes,1I1UJ@117743|Flavobacteriia,2NUBX@237|Flavobacterium	976|Bacteroidetes	UW	arginyl-trna synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_678782_1	391603.FBALC1_12542	1.071e-83	304.0	COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CSH2_k127_678782_3	925409.KI911562_gene1532	3.779e-55	195.0	2E373@1|root,32Y6V@2|Bacteria,4NWZF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_680981_0	929703.KE386491_gene113	1.621e-134	436.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CSH2_k127_684893_0	504472.Slin_3009	1.409e-43	169.0	COG0584@1|root,COG0584@2|Bacteria,4NE2E@976|Bacteroidetes,47VK9@768503|Cytophagia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD
CSH2_k127_686777_2	1123248.KB893337_gene2466	1.456e-54	198.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,1IYXS@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
CSH2_k127_686777_0	925409.KI911562_gene2439	1.308e-169	537.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CSH2_k127_686777_1	700598.Niako_2024	8.183e-123	405.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1IP1J@117747|Sphingobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
CSH2_k127_686777_3	1123248.KB893325_gene1160	1.254e-29	120.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CSH2_k127_696161_2	1267211.KI669560_gene364	1.132e-50	183.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
CSH2_k127_696161_1	929556.Solca_1229	2.726e-105	355.0	COG3187@1|root,COG3187@2|Bacteria,4NEY0@976|Bacteroidetes,1IQ5Y@117747|Sphingobacteriia	976|Bacteroidetes	O	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3,META
CSH2_k127_696161_3	360911.EAT1b_1947	7.059e-24	103.0	COG0477@1|root,COG2814@2|Bacteria,1W0BF@1239|Firmicutes,4HY4K@91061|Bacilli	91061|Bacilli	EGP	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
CSH2_k127_696161_0	700598.Niako_5795	1.746e-211	664.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CSH2_k127_696750_1	1267211.KI669560_gene2801	1.136e-27	114.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1IR07@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CSH2_k127_696750_0	700598.Niako_6927	6.982e-123	400.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1IQNE@117747|Sphingobacteriia	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CSH2_k127_706844_1	1033732.CAHI01000020_gene4	0.0001152	54.0	2F73I@1|root,33ZJ4@2|Bacteria,4NSYN@976|Bacteroidetes,2FQTH@200643|Bacteroidia	976|Bacteroidetes	S	Putative binding domain, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BACON
CSH2_k127_706844_0	1034807.FBFL15_1314	1.422e-36	154.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia,2NT4M@237|Flavobacterium	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
CSH2_k127_712285_0	925409.KI911562_gene1980	6.082e-215	672.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1IPB8@117747|Sphingobacteriia	976|Bacteroidetes	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CSH2_k127_713751_1	1123248.KB893370_gene4961	5.15e-24	102.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1IPUW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CSH2_k127_713751_0	1123278.KB893572_gene2245	2.978e-38	153.0	28HQQ@1|root,2ZY2I@2|Bacteria,4P72F@976|Bacteroidetes,47WCY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_713751_2	929703.KE386491_gene1249	9.491e-09	58.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CSH2_k127_715523_0	485918.Cpin_1672	2.445e-84	286.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5I@976|Bacteroidetes,1IW68@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CSH2_k127_715523_1	1267211.KI669560_gene2047	1.374e-33	132.0	2BH0I@1|root,32B0P@2|Bacteria,4P6EF@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835,DUF3658
CSH2_k127_719224_2	688270.Celal_4232	4.671e-40	151.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes,1I2DH@117743|Flavobacteriia	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CSH2_k127_719224_0	1202532.FF52_18215	5.922e-83	283.0	COG2067@1|root,COG2067@2|Bacteria,4NQHN@976|Bacteroidetes,1I6SN@117743|Flavobacteriia,2NVGV@237|Flavobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CSH2_k127_719224_1	159450.NH14_09675	3.507e-54	197.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1K18V@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CSH2_k127_722296_0	1123248.KB893315_gene3125	3.435e-255	806.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CSH2_k127_722296_2	700598.Niako_4374	1.306e-45	176.0	COG0589@1|root,COG0589@2|Bacteria,4NPYE@976|Bacteroidetes,1ISGK@117747|Sphingobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CSH2_k127_722296_1	700598.Niako_0396	1.055e-56	201.0	COG2382@1|root,COG2382@2|Bacteria,4NI86@976|Bacteroidetes,1IQ5J@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CSH2_k127_726640_0	1004149.AFOE01000017_gene784	1.013e-82	284.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_729299_1	1267211.KI669560_gene1022	3.995e-106	348.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes	976|Bacteroidetes	M	RagB, SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
CSH2_k127_729299_0	1267211.KI669560_gene1021	2.212e-265	825.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_729508_0	1123248.KB893321_gene543	1.28e-215	680.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
CSH2_k127_729508_1	1123248.KB893321_gene543	9.891e-87	291.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
CSH2_k127_730306_0	929703.KE386491_gene1945	5.372e-104	353.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
CSH2_k127_73834_0	1189612.A33Q_2380	4.129e-205	676.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
CSH2_k127_740316_1	1267211.KI669560_gene1901	6.669e-89	298.0	2AUDP@1|root,31K1P@2|Bacteria,4NRCQ@976|Bacteroidetes,1IYFT@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2452)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2452
CSH2_k127_740316_2	929713.NIASO_04055	1.449e-72	250.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1IS2U@117747|Sphingobacteriia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
CSH2_k127_740316_0	1267211.KI669560_gene1465	1.217e-98	323.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1IPD0@117747|Sphingobacteriia	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CSH2_k127_752190_2	1273538.G159_05470	1.773e-06	55.0	COG1028@1|root,COG1028@2|Bacteria,1TVGW@1239|Firmicutes,4HAP9@91061|Bacilli,26GQE@186818|Planococcaceae	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_752190_1	646529.Desaci_1750	5.743e-10	66.0	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V3CX@1239|Firmicutes,24IC2@186801|Clostridia,261SK@186807|Peptococcaceae	186801|Clostridia	C	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CSH2_k127_752190_0	468059.AUHA01000004_gene2343	5.1e-58	206.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1IP4Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CSH2_k127_752340_1	1267211.KI669560_gene1971	4.515e-147	473.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1IPB4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CSH2_k127_752340_2	1123248.KB893321_gene545	5.856e-30	127.0	COG0845@1|root,COG0845@2|Bacteria,4NTDH@976|Bacteroidetes,1ITXB@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
CSH2_k127_752340_0	1123248.KB893321_gene544	6e-205	649.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_757833_0	1123248.KB893386_gene1863	2.957e-148	474.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1INWU@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CSH2_k127_760875_0	929713.NIASO_01610	7.619e-179	562.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CSH2_k127_764497_0	1267211.KI669560_gene347	6.822e-42	169.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,Cadherin-like,Calx-beta,Flg_new
CSH2_k127_770437_2	1379270.AUXF01000007_gene997	2.299e-19	94.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CSH2_k127_770437_0	700598.Niako_7085	2.665e-150	483.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1IPFD@117747|Sphingobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CSH2_k127_770437_1	925409.KI911562_gene1317	9.484e-27	114.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1IPFD@117747|Sphingobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CSH2_k127_770437_3	925409.KI911562_gene1315	3.473e-11	63.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CSH2_k127_776312_0	925409.KI911562_gene1789	1.814e-85	285.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CSH2_k127_776312_1	925409.KI911562_gene1790	1.449e-82	278.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CSH2_k127_776312_2	1408433.JHXV01000021_gene1638	3.305e-28	115.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia,2PANG@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CSH2_k127_792236_2	700598.Niako_1270	3.556e-90	300.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes,1IRKA@117747|Sphingobacteriia	976|Bacteroidetes	O	SPTR Hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
CSH2_k127_792236_0	700598.Niako_1271	1.162e-155	497.0	COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes,1IPJ1@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM AIR synthase related protein, N-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
CSH2_k127_792236_3	986075.CathTA2_0423	3.419e-39	153.0	COG0398@1|root,COG0398@2|Bacteria,1V19V@1239|Firmicutes,4HEIJ@91061|Bacilli	91061|Bacilli	S	PFAM SNARE associated Golgi protein	yqeD	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CSH2_k127_792236_1	700598.Niako_5695	2.109e-105	346.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
CSH2_k127_817996_0	860228.Ccan_10730	1.561e-240	752.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia,1EREB@1016|Capnocytophaga	976|Bacteroidetes	H	Formyltetrahydrofolate synthetase	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CSH2_k127_817996_1	1123248.KB893322_gene598	2.692e-39	151.0	COG2318@1|root,COG2318@2|Bacteria,4NPSF@976|Bacteroidetes	976|Bacteroidetes	S	Pfam DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CSH2_k127_817996_2	925409.KI911562_gene1496	3.881e-34	134.0	COG0626@1|root,COG0626@2|Bacteria,4NJRK@976|Bacteroidetes,1IP3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CSH2_k127_822205_0	926562.Oweho_2108	2.893e-62	226.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2PBG6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PKD
CSH2_k127_827257_0	925409.KI911562_gene419	7.875e-204	636.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_827257_1	1267211.KI669560_gene2783	1.833e-50	185.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1IQ4I@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CSH2_k127_835078_1	926556.Echvi_3204	1.66e-42	167.0	COG4319@1|root,COG4319@2|Bacteria,4PKP4@976|Bacteroidetes,47YGA@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CSH2_k127_835078_0	700598.Niako_6067	1.248e-243	760.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1INZ2@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
CSH2_k127_843508_0	1123248.KB893348_gene360	4.048e-73	250.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1IR38@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_843508_1	1123248.KB893348_gene361	4.224e-36	146.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IUXA@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
CSH2_k127_843572_2	742766.HMPREF9455_03648	2.412e-07	62.0	2CMCG@1|root,32SEA@2|Bacteria,4NTTZ@976|Bacteroidetes,2FX5X@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_843572_1	925409.KI911562_gene1428	1.029e-92	309.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1IQPW@117747|Sphingobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CSH2_k127_843572_0	1123248.KB893314_gene3634	1.18e-223	713.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
CSH2_k127_86673_2	929713.NIASO_09270	3.224e-44	168.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes	976|Bacteroidetes	S	cytochrome c biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CSH2_k127_86673_0	1150600.ADIARSV_1112	2.731e-75	256.0	2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,1ISA1@117747|Sphingobacteriia	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
CSH2_k127_86673_1	1358423.N180_10080	4.625e-47	169.0	COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IV39@117747|Sphingobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CSH2_k127_86806_0	1267211.KI669560_gene2835	4.887e-272	843.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes	976|Bacteroidetes	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CSH2_k127_86806_1	1270196.JCKI01000003_gene2266	0.0009923	43.0	COG2374@1|root,COG3210@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG2374@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,4NTNN@976|Bacteroidetes,1J0H7@117747|Sphingobacteriia	976|Bacteroidetes	MU	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
CSH2_k127_868369_1	700598.Niako_3423	1.525e-23	102.0	COG3897@1|root,COG3897@2|Bacteria,4P696@976|Bacteroidetes,1IZ1E@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
CSH2_k127_868369_0	485917.Phep_2046	1.869e-109	360.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1IR0G@117747|Sphingobacteriia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
CSH2_k127_88210_0	391603.FBALC1_04557	2.197e-161	521.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1HX0V@117743|Flavobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CSH2_k127_88210_1	1123277.KB893201_gene6421	5.709e-12	66.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	2|Bacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CSH2_k127_88511_2	929556.Solca_0259	8.426e-57	209.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CSH2_k127_88511_0	1279009.ADICEAN_02119	1.984e-126	406.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_88511_1	1150600.ADIARSV_1285	8.406e-103	338.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1IPZS@117747|Sphingobacteriia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
CSH2_k127_893901_1	700598.Niako_4473	1.25e-63	239.0	COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,1IR65@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CSH2_k127_893901_0	1123248.KB893315_gene3093	1.614e-107	369.0	COG0845@1|root,COG0845@2|Bacteria,4NGVX@976|Bacteroidetes,1IQ7U@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG1566 Multidrug resistance efflux pump	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CSH2_k127_897252_0	700598.Niako_5461	1.335e-140	458.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1IQGQ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CSH2_k127_911743_3	1122604.JONR01000007_gene2855	1.286e-27	116.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,1X8HZ@135614|Xanthomonadales	135614|Xanthomonadales	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
CSH2_k127_911743_2	485918.Cpin_6268	7.023e-35	139.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1ITC4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CSH2_k127_911743_1	929556.Solca_1796	4.025e-42	164.0	2ATWF@1|root,31JFP@2|Bacteria,4NT3Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_911743_0	1123248.KB893314_gene3687	5.771e-99	325.0	COG0448@1|root,COG0448@2|Bacteria,4PKFG@976|Bacteroidetes,1IPMM@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
CSH2_k127_917260_0	1123248.KB893337_gene2460	2.021e-189	602.0	COG4206@1|root,COG4206@2|Bacteria,4PKY5@976|Bacteroidetes,1IQUU@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CSH2_k127_923015_0	929556.Solca_2958	2.398e-239	756.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQPI@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
CSH2_k127_923015_1	1123248.KB893323_gene1602	2.117e-35	146.0	COG1266@1|root,COG1266@2|Bacteria,4NHRW@976|Bacteroidetes,1IYXV@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CSH2_k127_923015_2	666684.AfiDRAFT_3357	1.518e-23	102.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,3JSXW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_928409_2	925409.KI911562_gene1571	1.618e-27	112.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,1IP4Y@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CSH2_k127_928409_0	760192.Halhy_6235	1.671e-109	363.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes	976|Bacteroidetes	S	COGs COG3752 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
CSH2_k127_928409_1	1267211.KI669560_gene2468	3.272e-65	224.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CSH2_k127_930716_0	700598.Niako_4449	3.504e-63	223.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IWX4@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_930716_1	525897.Dbac_1402	1.15e-22	103.0	COG3187@1|root,COG3187@2|Bacteria,1NABM@1224|Proteobacteria,42XQV@68525|delta/epsilon subdivisions,2WSV2@28221|Deltaproteobacteria,2MDUQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META,YscW
CSH2_k127_930716_2	194867.ALBQ01000011_gene384	1.79e-08	59.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CSH2_k127_931820_1	1122605.KB893628_gene4403	1.845e-54	196.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1IZCY@117747|Sphingobacteriia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
CSH2_k127_931820_3	760192.Halhy_0595	7.45e-32	134.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	5.3.1.16	ko:K01814,ko:K03825	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CSH2_k127_931820_0	926550.CLDAP_00380	4.814e-166	533.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CSH2_k127_931820_2	925409.KI911562_gene502	1.395e-51	192.0	COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1IT6C@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CSH2_k127_934083_0	485918.Cpin_3436	3.83e-114	392.0	COG4249@1|root,COG4249@2|Bacteria,4NH9I@976|Bacteroidetes	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
CSH2_k127_934083_1	1121887.AUDK01000002_gene2123	5.443e-15	78.0	COG2217@1|root,COG2217@2|Bacteria,4NYQS@976|Bacteroidetes,1IKQ0@117743|Flavobacteriia,2NXMJ@237|Flavobacterium	976|Bacteroidetes	P	Heavy metal translocating P-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_944160_0	1123248.KB893316_gene4542	1.277e-93	313.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1IQIH@117747|Sphingobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CSH2_k127_944558_2	886379.AEWI01000139_gene2247	1.329e-17	87.0	2BK9M@1|root,32EPT@2|Bacteria,4PQ17@976|Bacteroidetes,2G1BH@200643|Bacteroidia,3XM11@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_944558_3	1392498.JQLH01000001_gene1743	2.073e-14	79.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia,2PHRY@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_944558_0	925409.KI911562_gene762	4.958e-172	544.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CSH2_k127_945996_1	714943.Mucpa_4846	1.548e-65	233.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1INSH@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CSH2_k127_945996_2	1150600.ADIARSV_1291	1.138e-49	185.0	COG2867@1|root,COG2867@2|Bacteria,4NNHS@976|Bacteroidetes,1ISH1@117747|Sphingobacteriia	976|Bacteroidetes	I	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
CSH2_k127_945996_0	1237149.C900_03063	6.129e-69	239.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,47PVI@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
CSH2_k127_951489_1	1123248.KB893348_gene249	3.815e-74	255.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,1IPUY@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
CSH2_k127_951489_0	700598.Niako_5110	4.698e-135	439.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1IPJR@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CSH2_k127_95197_1	1123248.KB893386_gene1852	5.411e-99	330.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CSH2_k127_95197_0	925409.KI911562_gene1081	8.496e-117	379.0	COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1IP93@117747|Sphingobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CSH2_k127_95197_2	925409.KI911562_gene1082	5.544e-99	333.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1IQ6P@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
CSH2_k127_961825_1	700598.Niako_6693	4.309e-58	209.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1IP8I@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
CSH2_k127_961825_2	700598.Niako_6693	1.639e-36	138.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1IP8I@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 37	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
CSH2_k127_961825_0	929562.Emtol_0669	3.407e-75	264.0	COG0596@1|root,COG0596@2|Bacteria,4PMBK@976|Bacteroidetes,47PBT@768503|Cytophagia	976|Bacteroidetes	S	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
CSH2_k127_966566_1	525257.HMPREF0204_12135	1.134e-25	118.0	2A7BD@1|root,30W82@2|Bacteria,4PGK4@976|Bacteroidetes,1IM33@117743|Flavobacteriia,3ZSKS@59732|Chryseobacterium	976|Bacteroidetes	S	Hyaluronidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_56
CSH2_k127_966566_0	28229.ND2E_2313	4.393e-27	115.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,2Q6GG@267889|Colwelliaceae	1236|Gammaproteobacteria	E	PFAM asparagine synthase, glutamine amidotransferase class-II	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CSH2_k127_969441_1	395019.Bmul_2153	7.559e-54	194.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,1K4AM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_1	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CSH2_k127_969441_0	504472.Slin_1870	1.304e-64	226.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47P9R@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CSH2_k127_974599_0	929556.Solca_3634	6.976e-59	206.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
CSH2_k127_974599_1	1267211.KI669560_gene110	1.304e-49	178.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1ITK5@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CSH2_k127_974599_2	1121875.KB907548_gene1503	2.026e-15	87.0	COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes,1I1N3@117743|Flavobacteriia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CSH2_k127_975076_0	700598.Niako_0505	2.712e-05	57.0	COG4447@1|root,COG5492@1|root,COG4447@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,PIG-L,VCBS,WxL
CSH2_k127_976961_2	925409.KI911562_gene2659	1.608e-79	268.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1ISGF@117747|Sphingobacteriia	976|Bacteroidetes	FJ	COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CSH2_k127_976961_1	1267211.KI669560_gene1992	5.789e-122	398.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1IQ9S@117747|Sphingobacteriia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CSH2_k127_976961_0	1267211.KI669560_gene2439	1.041e-144	461.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CSH2_k127_979281_1	1123248.KB893316_gene4649	4.296e-44	163.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1IQ9E@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
CSH2_k127_979281_0	1122605.KB893645_gene1102	2.554e-83	284.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes	976|Bacteroidetes	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
CSH2_k127_979281_2	700598.Niako_0891	2.124e-17	83.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CSH2_k127_980974_1	485918.Cpin_3065	2.444e-28	116.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
CSH2_k127_980974_0	1267211.KI669560_gene1534	1.588e-144	466.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CSH2_k127_986852_0	1279009.ADICEAN_02492	9.222e-133	428.0	COG0282@1|root,COG0282@2|Bacteria,4NFI0@976|Bacteroidetes,47NZB@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CSH2_k127_986852_1	402612.FP2508	4.616e-15	76.0	COG1595@1|root,COG1595@2|Bacteria,4NQ2R@976|Bacteroidetes,1I3N7@117743|Flavobacteriia,2NUFF@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_990561_5	485918.Cpin_1630	1.001e-39	148.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CSH2_k127_990561_4	485918.Cpin_1631	1.112e-48	176.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1ITI7@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CSH2_k127_990561_2	485918.Cpin_1632	4.056e-90	299.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1IQ9B@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CSH2_k127_990561_6	1267211.KI669560_gene1335	1.857e-18	86.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1IUA3@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CSH2_k127_990561_3	1123248.KB893314_gene3306	5.793e-67	230.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1IRSX@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CSH2_k127_990561_0	1267211.KI669560_gene1337	1.682e-231	722.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1IPEC@117747|Sphingobacteriia	976|Bacteroidetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CSH2_k127_990561_1	1123248.KB893314_gene3304	7.456e-105	344.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1IP59@117747|Sphingobacteriia	976|Bacteroidetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
## 2850 queries scanned
## Total time (seconds): 26.3477840423584
## Rate: 108.17 q/s