## Tue Nov 12 02:05:03 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CSH2_bin.3.fa -m mmseqs --itype genome -o CSH2_bin.3 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CSH2_bin.3 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CSH2_k127_1004823_0	431947.PGN_0989	1.335e-68	242.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,2FN8Z@200643|Bacteroidia,22WBB@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CSH2_k127_1004823_1	761193.Runsl_4993	8.736e-29	120.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,47RES@768503|Cytophagia	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CSH2_k127_1004823_2	1122621.ATZA01000014_gene3239	4.053e-13	75.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IP00@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
CSH2_k127_1008516_4	1121930.AQXG01000001_gene1528	5.303e-05	47.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,1IQ6P@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
CSH2_k127_1008516_0	525373.HMPREF0766_10327	2.99e-82	287.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1IPJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CSH2_k127_1008516_1	755732.Fluta_3942	1.193e-54	199.0	COG2197@1|root,COG2197@2|Bacteria,4NNVV@976|Bacteroidetes,1ICPE@117743|Flavobacteriia,2PBHR@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CSH2_k127_1008516_3	1203611.KB894542_gene631	4.481e-33	139.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,2FNFM@200643|Bacteroidia	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CSH2_k127_1008516_2	1408433.JHXV01000010_gene640	9.457e-39	152.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,1IMPM@117743|Flavobacteriia,2PAJF@246874|Cryomorphaceae	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CSH2_k127_1010483_0	1123400.KB904752_gene858	1.59e-31	141.0	COG0823@1|root,COG2834@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2834@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
CSH2_k127_1010483_1	1192034.CAP_0870	1.076e-10	74.0	COG4935@1|root,COG5492@1|root,COG4935@2|Bacteria,COG5492@2|Bacteria,1R2U6@1224|Proteobacteria	2|Bacteria	O	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF4215,LRR_5,P_proprotein
CSH2_k127_1018258_0	1313301.AUGC01000004_gene2435	9.032e-87	299.0	COG2356@1|root,COG2373@1|root,COG2356@2|Bacteria,COG2373@2|Bacteria,4NEGS@976|Bacteroidetes	976|Bacteroidetes	L	Nuclease, EndA NucM family	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
CSH2_k127_1018258_1	1166018.FAES_0185	1.239e-23	106.0	COG0607@1|root,COG3118@1|root,COG0607@2|Bacteria,COG3118@2|Bacteria,4NUPH@976|Bacteroidetes,47PJB@768503|Cytophagia	976|Bacteroidetes	OP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
CSH2_k127_1031099_0	762903.Pedsa_2021	4.594e-210	666.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CSH2_k127_1031099_2	869213.JCM21142_41822	3.346e-52	188.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,47P99@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CSH2_k127_1031099_3	984262.SGRA_0696	6.149e-12	73.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CSH2_k127_1031099_1	1122179.KB890491_gene4456	2.084e-74	258.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1IQYP@117747|Sphingobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CSH2_k127_103749_2	1123234.AUKI01000014_gene2421	5.093e-44	166.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
CSH2_k127_103749_3	1267211.KI669560_gene1570	7.713e-35	141.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CSH2_k127_103749_1	929556.Solca_3194	2.366e-74	254.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_103749_0	755732.Fluta_3269	4.945e-110	366.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia,2PA99@246874|Cryomorphaceae	976|Bacteroidetes	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
CSH2_k127_103749_4	926569.ANT_06550	3.641e-05	51.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CSH2_k127_1041691_0	1550091.JROE01000013_gene40	5.384e-167	536.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CSH2_k127_1041691_1	1356852.N008_12215	1.573e-90	314.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
CSH2_k127_1047275_1	1123508.JH636439_gene1132	3.719e-07	61.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
CSH2_k127_1047275_0	1150600.ADIARSV_2900	3.296e-49	193.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_104761_0	1286631.X805_24910	3.512e-193	621.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,1KIWS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CSH2_k127_104761_1	153721.MYP_1667	9.174e-52	191.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CSH2_k127_1058451_0	929556.Solca_2039	1.635e-233	727.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CSH2_k127_1058451_1	926549.KI421517_gene3471	1.283e-65	229.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,47PC6@768503|Cytophagia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CSH2_k127_1058451_4	1120951.AUBG01000007_gene294	1.933e-19	90.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1I52P@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CSH2_k127_1058451_3	865938.Weevi_1268	8.018e-45	165.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CSH2_k127_1058451_2	391587.KAOT1_11121	3.624e-57	207.0	COG3698@1|root,COG3698@2|Bacteria,4NMNC@976|Bacteroidetes,1I2JV@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
CSH2_k127_1058451_5	319224.Sputcn32_0405	3.992e-15	76.0	COG3942@1|root,COG3942@2|Bacteria,1RDN2@1224|Proteobacteria,1S3SU@1236|Gammaproteobacteria,2QBCP@267890|Shewanellaceae	1236|Gammaproteobacteria	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
CSH2_k127_106779_1	755732.Fluta_2018	2.948e-82	276.0	COG1917@1|root,COG1917@2|Bacteria,4PKJ0@976|Bacteroidetes,1IJAI@117743|Flavobacteriia,2PAU2@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
CSH2_k127_106779_0	1227739.Hsw_0111	3.496e-158	505.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
CSH2_k127_106779_2	755732.Fluta_2012	4.887e-27	113.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IG7B@117743|Flavobacteriia,2PBE8@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_1070598_1	1408433.JHXV01000008_gene221	6.105e-05	54.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1070598_0	929556.Solca_2020	5.216e-78	265.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CSH2_k127_1072842_1	1408433.JHXV01000033_gene1155	4.802e-52	195.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1072842_2	391598.FBBAL38_12625	8.426e-26	109.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the ClpS family	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CSH2_k127_1072842_0	385682.AFSL01000064_gene1700	3.88e-83	281.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,2FQJ1@200643|Bacteroidia,3XJXP@558415|Marinilabiliaceae	976|Bacteroidetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CSH2_k127_1082216_1	755732.Fluta_0602	4.207e-05	51.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_3
CSH2_k127_1082216_0	1131812.JQMS01000001_gene40	8.051e-101	340.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
CSH2_k127_1083219_1	700598.Niako_3260	1.679e-39	157.0	COG0628@1|root,COG0628@2|Bacteria,4NPIX@976|Bacteroidetes,1IVAD@117747|Sphingobacteriia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CSH2_k127_1083219_0	1121904.ARBP01000002_gene7294	0.0	1087.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47NQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CSH2_k127_1083250_1	1250232.JQNJ01000001_gene1924	1.227e-11	70.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
CSH2_k127_1083250_0	1123248.KB893386_gene1898	1.848e-306	947.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
CSH2_k127_1100305_1	929556.Solca_1949	1.045e-40	164.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1IRD3@117747|Sphingobacteriia	976|Bacteroidetes	S	ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
CSH2_k127_1100305_2	929556.Solca_4261	2.09e-34	139.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,1IT01@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
CSH2_k127_1100305_0	1168289.AJKI01000031_gene1088	2.621e-62	227.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,2G3HG@200643|Bacteroidia,3XJX6@558415|Marinilabiliaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
CSH2_k127_1104303_1	1408473.JHXO01000010_gene3577	2.946e-09	59.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CSH2_k127_1104303_0	153721.MYP_2228	3.102e-212	681.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CSH2_k127_1111558_0	391603.FBALC1_12922	1.939e-49	193.0	COG1361@1|root,COG4886@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,4PMHH@976|Bacteroidetes,1IJT5@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_1111558_1	313606.M23134_01806	2.967e-12	75.0	2D6WA@1|root,32TMZ@2|Bacteria,4NU16@976|Bacteroidetes,47VUX@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CSH2_k127_1117417_3	1118060.CAGZ01000005_gene1638	3.671e-21	94.0	COG1051@1|root,COG3727@1|root,COG1051@2|Bacteria,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4CV6Q@84998|Coriobacteriia	84998|Coriobacteriia	L	DNA mismatch endonuclease vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,Vsr
CSH2_k127_1117417_2	1237149.C900_03250	2.635e-25	109.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,47RYW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1117417_0	1120965.AUBV01000014_gene1159	1.633e-142	462.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
CSH2_k127_1117417_1	153721.MYP_3673	1.64e-84	287.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,47M4W@768503|Cytophagia	976|Bacteroidetes	L	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CSH2_k127_1119763_0	1279009.ADICEAN_02027	3.013e-217	681.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CSH2_k127_1119763_1	1236514.BAKL01000057_gene3952	1.133e-48	183.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,2FMCA@200643|Bacteroidia,4AMA8@815|Bacteroidaceae	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CSH2_k127_1119763_2	1227739.Hsw_1007	4.352e-26	119.0	COG2911@1|root,COG2931@1|root,COG3391@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,4PMEU@976|Bacteroidetes,47RH2@768503|Cytophagia	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Laminin_G_3
CSH2_k127_1122233_0	1454007.JAUG01000026_gene901	2.788e-79	268.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
CSH2_k127_1145978_2	755732.Fluta_2055	3.321e-09	59.0	COG0438@1|root,COG0438@2|Bacteria,4PI5K@976|Bacteroidetes,1IGDT@117743|Flavobacteriia,2PB9M@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_1145978_1	113395.AXAI01000011_gene6419	1.309e-43	169.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CSH2_k127_1145978_0	755732.Fluta_2749	4.116e-240	749.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWVS@117743|Flavobacteriia,2PAHG@246874|Cryomorphaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CSH2_k127_1150346_3	1189612.A33Q_3166	8.951e-14	78.0	COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,47JX5@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	ykuF	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
CSH2_k127_1150346_2	1173024.KI912149_gene5730	6.875e-19	98.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
CSH2_k127_1150346_1	1408433.JHXV01000005_gene2331	5.326e-39	149.0	2A94Y@1|root,30Y99@2|Bacteria,4PC0Q@976|Bacteroidetes,1ICRR@117743|Flavobacteriia,2PBX3@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1150346_0	1121957.ATVL01000007_gene1691	3.563e-194	620.0	COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia	976|Bacteroidetes	H	magnesium chelatase	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Sigma54_activat
CSH2_k127_1150346_4	313590.MED134_05004	1.79e-10	61.0	COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,1HWJG@117743|Flavobacteriia,37DJR@326319|Dokdonia	976|Bacteroidetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CSH2_k127_1151847_2	1229276.DI53_0579	2.155e-26	110.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1IQTX@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CSH2_k127_1151847_0	1408433.JHXV01000015_gene1753	8.465e-102	342.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1HX9P@117743|Flavobacteriia,2PAQ3@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CSH2_k127_1151847_1	1408433.JHXV01000015_gene1754	2.584e-32	128.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1HXCB@117743|Flavobacteriia,2PAS5@246874|Cryomorphaceae	976|Bacteroidetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
CSH2_k127_1161775_2	746697.Aeqsu_2259	2.501e-41	161.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CSH2_k127_1161775_3	1408433.JHXV01000029_gene3070	2.658e-26	109.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1IB4Z@117743|Flavobacteriia,2PBZ3@246874|Cryomorphaceae	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine (FGAM) synthase	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
CSH2_k127_1161775_0	1094466.KQS_03540	3.04e-113	374.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia,2NU9K@237|Flavobacterium	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CSH2_k127_1161775_1	153721.MYP_191	1.445e-78	270.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MWA@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_1163395_1	886293.Sinac_3632	6.154e-33	129.0	COG4804@1|root,COG4804@2|Bacteria,2IY91@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
CSH2_k127_1163395_2	1279009.ADICEAN_01494	2.343e-07	60.0	28ZRK@1|root,2ZMGF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1163395_0	506534.Rhein_2111	1.161e-127	413.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1WWMA@135613|Chromatiales	135613|Chromatiales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	peroxidase
CSH2_k127_1167142_1	1406840.Q763_05245	5.194e-59	210.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia,2NSQF@237|Flavobacterium	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CSH2_k127_1167142_3	1197477.IA57_02120	7.76e-26	118.0	2DM8U@1|root,3273Z@2|Bacteria,4NQC2@976|Bacteroidetes,1I2Y5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1167142_0	452637.Oter_3918	5.75e-179	573.0	COG0477@1|root,COG0477@2|Bacteria,46XDR@74201|Verrucomicrobia,3K91S@414999|Opitutae	414999|Opitutae	U	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_1167142_2	1122179.KB890436_gene1406	1.631e-48	188.0	COG1836@1|root,COG1836@2|Bacteria,4NPN7@976|Bacteroidetes,1IUFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
CSH2_k127_1180484_0	468059.AUHA01000002_gene32	1.546e-116	395.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CSH2_k127_1180484_1	869213.JCM21142_72561	3.064e-10	61.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,47KPQ@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CSH2_k127_1185751_0	313606.M23134_07914	5.478e-86	289.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47KDC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_1196854_0	755732.Fluta_1488	3.03e-109	372.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_119866_0	1124780.ANNU01000049_gene2204	4.533e-59	225.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4NIXZ@976|Bacteroidetes,47MCW@768503|Cytophagia	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,PAS,PAS_4,PAS_9,SpoIIE
CSH2_k127_1204167_0	153721.MYP_2617	6.267e-104	350.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
CSH2_k127_1204167_1	755732.Fluta_1951	6.512e-16	84.0	COG3291@1|root,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,1I16K@117743|Flavobacteriia,2PC6D@246874|Cryomorphaceae	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43
CSH2_k127_1206528_1	1408433.JHXV01000033_gene1144	5.418e-104	346.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia,2PABT@246874|Cryomorphaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CSH2_k127_1206528_0	504472.Slin_4957	3.377e-119	401.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KGA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CSH2_k127_1206528_2	1107311.Q767_13560	2.438e-34	136.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes,1I2UM@117743|Flavobacteriia,2NWMD@237|Flavobacterium	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CSH2_k127_1208662_1	755732.Fluta_0929	7.812e-122	404.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia,2PAIM@246874|Cryomorphaceae	976|Bacteroidetes	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CSH2_k127_1208662_2	743722.Sph21_4673	5.226e-50	183.0	COG1247@1|root,COG1247@2|Bacteria,4PM4N@976|Bacteroidetes,1ISGA@117747|Sphingobacteriia	976|Bacteroidetes	M	Gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CSH2_k127_1208662_0	675813.VIB_000587	4.91e-138	449.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,1RNFF@1236|Gammaproteobacteria,1XT96@135623|Vibrionales	135623|Vibrionales	G	Belongs to the FBPase class 1 family	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
CSH2_k127_1208662_3	1408433.JHXV01000008_gene155	1.395e-20	100.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia,2PA9W@246874|Cryomorphaceae	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CSH2_k127_1210273_0	929556.Solca_0021	7.114e-307	953.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CSH2_k127_121357_0	929556.Solca_2077	8.724e-301	942.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CSH2_k127_1218439_1	1313421.JHBV01000014_gene4039	3.428e-09	70.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1IXWG@117747|Sphingobacteriia	976|Bacteroidetes	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
CSH2_k127_1218439_0	1227739.Hsw_4070	7.737e-28	132.0	COG1361@1|root,COG2353@1|root,COG5184@1|root,COG5644@1|root,COG1361@2|Bacteria,COG2353@2|Bacteria,COG5184@2|Bacteria,COG5644@2|Bacteria,4PP3D@976|Bacteroidetes	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1220627_1	411901.BACCAC_00941	2.066e-16	87.0	COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,2FNR1@200643|Bacteroidia,4AKK3@815|Bacteroidaceae	976|Bacteroidetes	M	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
CSH2_k127_1220627_0	269798.CHU_0934	2.476e-239	750.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CSH2_k127_122255_0	1313301.AUGC01000001_gene1456	1.501e-77	270.0	COG0747@1|root,COG4288@1|root,COG0747@2|Bacteria,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes	976|Bacteroidetes	E	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
CSH2_k127_122255_1	649747.HMPREF0083_04442	1.65e-41	166.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	gabD	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CSH2_k127_1230312_0	1089547.KB913013_gene1913	3.621e-12	71.0	28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,47K71@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1249591_0	1121904.ARBP01000006_gene3681	1.686e-16	94.0	COG3419@1|root,COG4447@1|root,COG4932@1|root,COG5184@1|root,COG3419@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NNEI@976|Bacteroidetes	976|Bacteroidetes	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF1566
CSH2_k127_1251756_0	926562.Oweho_2228	4.008e-147	470.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,2PAFP@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_1251756_2	1089550.ATTH01000001_gene1602	3.658e-50	186.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,1FJF1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
CSH2_k127_1251756_1	1279009.ADICEAN_00512	1.204e-72	251.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
CSH2_k127_1251780_2	926562.Oweho_3551	3.417e-20	98.0	COG0239@1|root,COG0239@2|Bacteria,4P9SD@976|Bacteroidetes,1IEE9@117743|Flavobacteriia,2PBA2@246874|Cryomorphaceae	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CSH2_k127_1251780_1	886379.AEWI01000024_gene367	9.655e-37	146.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,2FRKS@200643|Bacteroidia,3XK0T@558415|Marinilabiliaceae	976|Bacteroidetes	I	Acid phosphatase homologues	ybjG	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CSH2_k127_1251780_0	1453500.AT05_10710	4.921e-150	480.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1HXN1@117743|Flavobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CSH2_k127_1251780_3	1121011.AUCB01000005_gene2445	2.579e-12	67.0	COG0563@1|root,COG0634@1|root,COG0563@2|Bacteria,COG0634@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia,23FWR@178469|Arenibacter	976|Bacteroidetes	F	AAA domain	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
CSH2_k127_1272254_2	1122179.KB890416_gene2721	0.000135	51.0	COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,1J1A0@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Reprolysin_4,fn3
CSH2_k127_1272254_0	313596.RB2501_05110	5.42e-46	174.0	COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,1I1BT@117743|Flavobacteriia	976|Bacteroidetes	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CSH2_k127_1272254_1	1408813.AYMG01000008_gene3848	1.184e-35	139.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ITGS@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CSH2_k127_1276003_1	1202532.FF52_21849	3.09e-29	134.0	COG2373@1|root,COG2911@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4677@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4677@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2P0KB@237|Flavobacterium	976|Bacteroidetes	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
CSH2_k127_1276003_0	1122225.AULQ01000002_gene492	2.266e-34	151.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes	976|Bacteroidetes	MU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PKD
CSH2_k127_1277094_0	1089547.KB913013_gene4561	2.39e-48	192.0	COG1404@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NPFV@976|Bacteroidetes	976|Bacteroidetes	MO	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1292058_0	1122605.KB893631_gene3942	1.058e-100	351.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
CSH2_k127_1292947_1	1227739.Hsw_2384	4.583e-73	260.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,47K4G@768503|Cytophagia	976|Bacteroidetes	M	COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_1292947_0	755732.Fluta_0750	8.481e-145	463.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1HWRR@117743|Flavobacteriia,2PAAC@246874|Cryomorphaceae	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CSH2_k127_1294215_0	755732.Fluta_1996	3.476e-151	486.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia,2PAA2@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CSH2_k127_1294215_1	1239962.C943_01163	3.265e-62	219.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
CSH2_k127_1294870_4	330214.NIDE0880	1.893e-05	50.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
CSH2_k127_1294870_1	663278.Ethha_0675	3.327e-79	280.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,3WJDG@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CSH2_k127_1294870_0	1211817.CCAT010000083_gene1670	3.349e-100	341.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,24BT3@186801|Clostridia,36F7W@31979|Clostridiaceae	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_1294870_3	755732.Fluta_2179	7.414e-18	96.0	COG3307@1|root,COG3307@2|Bacteria,4NXNX@976|Bacteroidetes,1ICS9@117743|Flavobacteriia,2PBZ8@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CSH2_k127_1294870_2	755732.Fluta_2193	6.926e-55	197.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,1HZBY@117743|Flavobacteriia,2PBDW@246874|Cryomorphaceae	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
CSH2_k127_1295821_1	1123256.KB907942_gene56	1.482e-74	261.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,1X3Q6@135614|Xanthomonadales	135614|Xanthomonadales	E	Dipeptidyl carboxypeptidase	dcp2	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CSH2_k127_1295821_0	1131451.O1K_10032	1.904e-141	456.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,1X3Q6@135614|Xanthomonadales	135614|Xanthomonadales	E	Dipeptidyl carboxypeptidase	dcp2	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CSH2_k127_1309769_1	1408433.JHXV01000014_gene3656	5.836e-81	286.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia,2PATF@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, transmembrane domain	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CSH2_k127_1309769_0	1408433.JHXV01000014_gene3657	3.275e-186	588.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia,2PAMC@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CSH2_k127_1315156_0	706436.HMPREF9074_07922	5.529e-108	355.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1HWNB@117743|Flavobacteriia,1ER8M@1016|Capnocytophaga	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CSH2_k127_1315156_1	1453500.AT05_00135	1.71e-46	181.0	2DNF9@1|root,32X73@2|Bacteria,4P48N@976|Bacteroidetes,1I9I8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1315747_2	313596.RB2501_04560	1.018e-25	107.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CSH2_k127_1315747_1	1166018.FAES_5300	8.667e-131	422.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,47KHD@768503|Cytophagia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CSH2_k127_1315747_0	760192.Halhy_3819	8.907e-192	628.0	COG0308@1|root,COG0842@1|root,COG1277@1|root,COG0308@2|Bacteria,COG0842@2|Bacteria,COG1277@2|Bacteria,4NF3R@976|Bacteroidetes,1IPQP@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_1318366_0	1218103.CIN01S_04_01210	5.938e-12	73.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1IEFN@117743|Flavobacteriia,3ZR82@59732|Chryseobacterium	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CSH2_k127_1318366_1	1192034.CAP_4229	3.744e-06	58.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CSH2_k127_1324668_0	755732.Fluta_3562	7.551e-61	216.0	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,1ICMZ@117743|Flavobacteriia,2PB21@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1324668_1	1121904.ARBP01000019_gene2759	1.297e-50	194.0	COG1596@1|root,COG1596@2|Bacteria,4NFXJ@976|Bacteroidetes,47Q2A@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CSH2_k127_1324668_2	575589.HMPREF0018_02653	4.962e-05	55.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,3NJIK@468|Moraxellaceae	1236|Gammaproteobacteria	D	G-rich domain on putative tyrosine kinase	wzc	GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
CSH2_k127_1325866_0	1123278.KB893607_gene4618	2.53e-86	288.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CSH2_k127_1325866_2	497964.CfE428DRAFT_5192	2.042e-25	110.0	COG2827@1|root,COG2827@2|Bacteria,46WUU@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CSH2_k127_1325866_1	886379.AEWI01000012_gene1053	1.963e-58	208.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,2FPZE@200643|Bacteroidia,3XJMJ@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosome recycling factor	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CSH2_k127_1337515_1	616991.JPOO01000001_gene3356	3.768e-25	109.0	COG0477@1|root,COG0607@1|root,COG0607@2|Bacteria,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,1HZ4T@117743|Flavobacteriia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_1337515_0	1123037.AUDE01000019_gene3324	9.002e-123	411.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1337545_0	755732.Fluta_2100	2.781e-146	468.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia,2PAHD@246874|Cryomorphaceae	976|Bacteroidetes	F	PFAM AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CSH2_k127_1337545_1	869213.JCM21142_104424	7.293e-67	244.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,47M9W@768503|Cytophagia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CSH2_k127_1354575_1	1313421.JHBV01000038_gene2841	3.045e-08	62.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF1983,DUF3672,Glyco_hydro_28,HYR,PA14,Pectate_lyase_3
CSH2_k127_1354575_0	1121912.AUHD01000004_gene1999	3.642e-57	220.0	COG4386@1|root,COG4886@1|root,COG4386@2|Bacteria,COG4886@2|Bacteria,4PPDK@976|Bacteroidetes,1IKIZ@117743|Flavobacteriia	976|Bacteroidetes	E	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_13628_0	760192.Halhy_5043	1.112e-178	580.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1IPGC@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CSH2_k127_13628_2	700598.Niako_5416	8.774e-06	50.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CSH2_k127_13628_1	1317122.ATO12_12045	3.366e-10	65.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1HZ3G@117743|Flavobacteriia,2YINV@290174|Aquimarina	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CSH2_k127_136702_2	268407.PWYN_08285	2.09e-07	54.0	COG0110@1|root,COG0110@2|Bacteria,1VUSR@1239|Firmicutes,4HVQE@91061|Bacilli,27526@186822|Paenibacillaceae	91061|Bacilli	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CSH2_k127_136702_0	497964.CfE428DRAFT_3091	7.371e-82	278.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CSH2_k127_136702_1	1121459.AQXE01000004_gene1766	1.479e-81	285.0	COG0438@1|root,COG0438@2|Bacteria,1PGDM@1224|Proteobacteria,4363T@68525|delta/epsilon subdivisions,2X9FF@28221|Deltaproteobacteria,2MCV1@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_136702_3	877424.ATWC01000006_gene312	0.0001075	47.0	COG0438@1|root,COG0438@2|Bacteria,1TRRW@1239|Firmicutes,24PRJ@186801|Clostridia,27NT7@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_1380927_1	1279009.ADICEAN_00761	2.829e-07	57.0	COG2919@1|root,COG2919@2|Bacteria,4P9WW@976|Bacteroidetes,47S83@768503|Cytophagia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CSH2_k127_1380927_0	649349.Lbys_3137	6.209e-197	619.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
CSH2_k127_1384354_0	1282362.AEAC466_11310	1.205e-300	936.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2KFZ6@204458|Caulobacterales	204458|Caulobacterales	EU	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CSH2_k127_1393781_0	13735.ENSPSIP00000006330	2.497e-11	75.0	KOG1130@1|root,KOG1130@2759|Eukaryota,39NJP@33154|Opisthokonta,3CQ3W@33208|Metazoa,3E69B@33213|Bilateria,48RPK@7711|Chordata,49N97@7742|Vertebrata,4CD68@8459|Testudines	33208|Metazoa	T	CHAT domain	TTC28	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
CSH2_k127_1402806_0	1392488.JHZY01000002_gene1485	1.847e-120	404.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia,2XJ39@283735|Leeuwenhoekiella	976|Bacteroidetes	L	helicase superfamily c-terminal domain	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CSH2_k127_1422101_0	1227739.Hsw_3730	4.304e-111	364.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CSH2_k127_1422101_2	1515615.HQ41_07955	7.111e-53	201.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,2FR7A@200643|Bacteroidia,22XVH@171551|Porphyromonadaceae	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CSH2_k127_1422101_1	243233.MCA1772	6.18e-68	239.0	COG2244@1|root,COG2244@2|Bacteria,1R512@1224|Proteobacteria,1RZ0F@1236|Gammaproteobacteria,1XE8D@135618|Methylococcales	135618|Methylococcales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CSH2_k127_1427844_0	269798.CHU_2225	1.625e-12	80.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
CSH2_k127_143263_0	1121898.Q766_17270	3.096e-147	475.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia,2NTFV@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
CSH2_k127_143263_1	203275.BFO_1452	1.677e-71	257.0	COG0803@1|root,COG4591@1|root,COG0803@2|Bacteria,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia,22X1B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
CSH2_k127_143263_2	926549.KI421517_gene1135	1.559e-16	79.0	COG0500@1|root,COG0500@2|Bacteria,4PP98@976|Bacteroidetes,47PJZ@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
CSH2_k127_1436810_0	1408473.JHXO01000011_gene3146	5.824e-131	432.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia	976|Bacteroidetes	O	peptidase Do	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
CSH2_k127_1436810_1	281090.Lxx15970	2.429e-08	57.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4FKHM@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CSH2_k127_144998_0	755732.Fluta_0944	3.001e-121	410.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2PAM4@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
CSH2_k127_144998_2	1408473.JHXO01000005_gene1648	5.77e-34	145.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,2FMWD@200643|Bacteroidia	976|Bacteroidetes	O	COG NOG23400 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
CSH2_k127_144998_1	1121957.ATVL01000006_gene2972	1.409e-39	155.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,47JPW@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
CSH2_k127_145290_2	1408433.JHXV01000015_gene1774	3.411e-12	72.0	2A5H4@1|root,30U7A@2|Bacteria,4PFFN@976|Bacteroidetes,1IMTB@117743|Flavobacteriia,2PC40@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_145290_1	761193.Runsl_0836	7.312e-34	138.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CSH2_k127_145290_0	1408433.JHXV01000015_gene1775	5.316e-131	427.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1HWWV@117743|Flavobacteriia,2PAHY@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CSH2_k127_1454348_1	755732.Fluta_1077	4.968e-61	220.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBB7@246874|Cryomorphaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
CSH2_k127_1454348_2	1408433.JHXV01000019_gene1917	1.656e-56	216.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1454348_3	1492738.FEM21_01540	4.898e-45	166.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1I4DW@117743|Flavobacteriia,2NW8H@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CSH2_k127_1454348_0	1121899.Q764_02345	9.549e-89	296.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia,2NSHX@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CSH2_k127_1457586_1	1501391.LG35_00125	3.145e-52	192.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,2FX4A@200643|Bacteroidia,22UPM@171550|Rikenellaceae	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CSH2_k127_1457586_0	1237149.C900_00367	6.413e-100	337.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,47JH0@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CSH2_k127_1465476_0	929556.Solca_3990	1.059e-223	702.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CSH2_k127_1465476_1	1408433.JHXV01000008_gene84	6.393e-11	71.0	COG0810@1|root,COG2849@1|root,COG0810@2|Bacteria,COG2849@2|Bacteria,4NW2U@976|Bacteroidetes,1IIR8@117743|Flavobacteriia	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
CSH2_k127_1466844_0	1223410.KN050846_gene2065	2.702e-127	413.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1HY1I@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CSH2_k127_1466844_1	1127692.HMPREF9075_01574	3.475e-93	311.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia,1EQAA@1016|Capnocytophaga	976|Bacteroidetes	IQ	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
CSH2_k127_147373_1	1453500.AT05_01165	9.691e-09	56.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1HWWI@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CSH2_k127_147373_0	926562.Oweho_1341	3.195e-121	404.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CSH2_k127_1481021_2	1122621.ATZA01000010_gene197	2.834e-12	76.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CSH2_k127_1481021_1	1341155.FSS13T_05640	9.107e-30	128.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia,2NWNU@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CSH2_k127_1481021_0	398720.MED217_00790	2.065e-107	359.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia,2XIU9@283735|Leeuwenhoekiella	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CSH2_k127_1483978_0	1236689.MMALV_14030	1.472e-162	520.0	COG5253@1|root,arCOG04169@2157|Archaea,2XT9A@28890|Euryarchaeota,3F2F6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
CSH2_k127_1483978_1	1236689.MMALV_14020	7.696e-19	93.0	COG1422@1|root,arCOG02673@2157|Archaea,2XZDK@28890|Euryarchaeota,3F2U5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Integral membrane protein DUF106	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
CSH2_k127_1497554_1	1122176.KB903579_gene4845	3.328e-26	114.0	COG1361@1|root,COG3209@1|root,COG4886@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG4886@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
CSH2_k127_1497554_0	485918.Cpin_3624	8.349e-70	248.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1IP9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_1497554_2	319236.JCM19294_2600	4.803e-11	73.0	COG1729@1|root,COG2885@1|root,COG1729@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,3HJVM@363408|Nonlabens	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
CSH2_k127_1499274_0	925409.KI911562_gene465	2.389e-92	309.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes	976|Bacteroidetes	P	Transport of potassium into the cell	-	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
CSH2_k127_1499274_1	1408433.JHXV01000003_gene229	6.032e-24	112.0	COG3209@1|root,COG5384@1|root,COG3209@2|Bacteria,COG5384@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
CSH2_k127_1517640_1	234267.Acid_4233	6.292e-15	80.0	COG3088@1|root,COG3088@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
CSH2_k127_1517640_0	1340493.JNIF01000003_gene4699	2.101e-193	611.0	COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CSH2_k127_1523490_1	589865.DaAHT2_1406	8.916e-31	126.0	COG1373@1|root,COG1373@2|Bacteria,1R8U5@1224|Proteobacteria,42M24@68525|delta/epsilon subdivisions,2WIJW@28221|Deltaproteobacteria,2MI22@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
CSH2_k127_1523490_0	1313421.JHBV01000043_gene3072	8.241e-204	638.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
CSH2_k127_1523490_2	1004149.AFOE01000012_gene1535	4.579e-10	59.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CSH2_k127_1523957_0	1121889.AUDM01000017_gene2162	6.743e-15	80.0	COG5295@1|root,COG5295@2|Bacteria,4NN21@976|Bacteroidetes,1I1UJ@117743|Flavobacteriia,2NUBX@237|Flavobacterium	976|Bacteroidetes	UW	arginyl-trna synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1525298_1	742726.HMPREF9448_02516	5.277e-109	361.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FN98@200643|Bacteroidia,22WA5@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CSH2_k127_1525298_3	984262.SGRA_0169	3.027e-25	114.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1ITIS@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CSH2_k127_1525298_2	1279009.ADICEAN_01109	2.607e-26	109.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,47RW0@768503|Cytophagia	976|Bacteroidetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CSH2_k127_1525298_0	1121904.ARBP01000002_gene7100	1.974e-174	566.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,47YHC@768503|Cytophagia	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CSH2_k127_1537251_1	1408433.JHXV01000005_gene2465	5.527e-142	455.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,2PBB2@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CSH2_k127_1537251_0	865938.Weevi_1166	4.291e-166	535.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CSH2_k127_1545888_0	411477.PARMER_03556	3.551e-43	174.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,2FMHC@200643|Bacteroidia,22WJ1@171551|Porphyromonadaceae	976|Bacteroidetes	M	ABC transporter permease	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CSH2_k127_1545888_1	504487.JCM19302_3289	3.452e-41	162.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CSH2_k127_1547757_0	1122165.AUHS01000047_gene3184	5.88e-106	366.0	COG1520@1|root,COG1520@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CSH2_k127_156040_2	1189619.pgond44_02498	4.466e-60	210.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia,4C3IN@83612|Psychroflexus	976|Bacteroidetes	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CSH2_k127_156040_1	1313421.JHBV01000030_gene2200	3.029e-95	327.0	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1INVF@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CSH2_k127_156040_0	700598.Niako_1516	3.51e-235	736.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1INP0@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CSH2_k127_1561333_1	1358423.N180_09365	1.681e-80	274.0	COG2850@1|root,COG2850@2|Bacteria,4NEJI@976|Bacteroidetes	976|Bacteroidetes	S	SMART transcription factor jumonji	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
CSH2_k127_1561333_3	1515613.HQ37_00060	8.333e-28	119.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,2FS5C@200643|Bacteroidia,22YEK@171551|Porphyromonadaceae	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
CSH2_k127_1561333_2	1279009.ADICEAN_01763	4.796e-39	150.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CSH2_k127_1561333_0	1122176.KB903550_gene4281	9.281e-108	370.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
CSH2_k127_1573090_5	1089550.ATTH01000001_gene2193	7.962e-15	79.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_11,AAA_12,AAA_13,AAA_15,AAA_23,DUF3732,SMC_N
CSH2_k127_1573090_6	887898.HMPREF0551_2483	2.671e-06	59.0	28KK4@1|root,2ZA50@2|Bacteria,1PNBZ@1224|Proteobacteria,2VMD7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1573090_0	1528106.JRJE01000027_gene452	7.298e-103	346.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2JPZ6@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	2.4.1.83,2.4.2.53	ko:K00721,ko:K10012	ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503	M00721,M00761	R01009,R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
CSH2_k127_1573090_1	882.DVU_3015	2.946e-48	184.0	COG4627@1|root,COG4627@2|Bacteria,1RKW8@1224|Proteobacteria,42V7S@68525|delta/epsilon subdivisions,2WRVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CSH2_k127_1573090_4	1499967.BAYZ01000014_gene6405	1.853e-23	114.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,PP-binding,ketoacyl-synt
CSH2_k127_1573090_2	1380394.JADL01000001_gene2725	2.091e-42	169.0	COG0500@1|root,COG2226@2|Bacteria,1R16F@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CSH2_k127_1573090_3	1192868.CAIU01000033_gene4226	1.151e-27	115.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,43IMQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CSH2_k127_1584969_0	714943.Mucpa_2198	7.138e-106	351.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_1584969_1	357276.EL88_22155	4.107e-33	133.0	COG1672@1|root,COG1672@2|Bacteria,4NJHR@976|Bacteroidetes,2G2GK@200643|Bacteroidia,4AVYQ@815|Bacteroidaceae	976|Bacteroidetes	S	ATPase domain predominantly from Archaea	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2
CSH2_k127_1595588_0	1124780.ANNU01000013_gene3830	2.048e-68	238.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,47M7C@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
CSH2_k127_1595588_1	1313421.JHBV01000014_gene3842	3.623e-48	178.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1ITHC@117747|Sphingobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
CSH2_k127_1595588_4	1123234.AUKI01000019_gene543	2.232e-12	69.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CSH2_k127_1595588_2	292459.STH494	1.87e-29	128.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CSH2_k127_1595588_3	471854.Dfer_3069	1.069e-21	97.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,47M8R@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CSH2_k127_1602505_0	755732.Fluta_1888	3.914e-170	552.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1HX5G@117743|Flavobacteriia,2PA5A@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CSH2_k127_1602505_2	714943.Mucpa_4284	2.806e-23	108.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1602505_1	880074.BARVI_05055	7.253e-42	163.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia,22WND@171551|Porphyromonadaceae	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CSH2_k127_1625862_0	1408433.JHXV01000008_gene224	3.743e-59	217.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1I0RF@117743|Flavobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CSH2_k127_1625862_1	929556.Solca_0390	1.677e-45	175.0	COG1028@1|root,COG1028@2|Bacteria,4PKBF@976|Bacteroidetes,1J0YN@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_1625862_2	591158.SSMG_05501	2.637e-14	75.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1625862_3	1131812.JQMS01000001_gene1095	3.637e-11	63.0	2EH3B@1|root,33AVB@2|Bacteria,4NXP5@976|Bacteroidetes,1I6KT@117743|Flavobacteriia,2NWVF@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_163716_2	1237149.C900_02867	3.347e-16	91.0	COG2242@1|root,COG2242@2|Bacteria,4PPRI@976|Bacteroidetes,47SAN@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CSH2_k127_163716_1	1120965.AUBV01000007_gene2564	2.469e-136	445.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CSH2_k127_163716_0	1168034.FH5T_12365	2.923e-149	485.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,2FMUQ@200643|Bacteroidia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CSH2_k127_1637640_1	755732.Fluta_2460	9.44e-124	405.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1HZ3R@117743|Flavobacteriia,2PA70@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1637640_0	755732.Fluta_2459	4.116e-133	466.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
CSH2_k127_1640844_2	313606.M23134_00414	7.383e-13	74.0	COG5395@1|root,COG5395@2|Bacteria,4NMDY@976|Bacteroidetes,47RKE@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
CSH2_k127_1640844_0	483219.LILAB_29395	1.539e-105	353.0	COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria,42ZA2@68525|delta/epsilon subdivisions,2X2MN@28221|Deltaproteobacteria,2YUIW@29|Myxococcales	28221|Deltaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CSH2_k127_1640844_1	1242864.D187_006631	1.334e-28	127.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	2.3.1.43	ko:K00650	ko00564,ko04979,map00564,map04979	-	R02114	RC00037,RC00055	ko00000,ko00001,ko01000	-	-	-	DUF900,LCAT,Peptidase_C14
CSH2_k127_1645703_0	485913.Krac_6669	7.176e-37	148.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CSH2_k127_165571_1	886379.AEWI01000030_gene300	2.391e-83	281.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,2FRYA@200643|Bacteroidia,3XJ8R@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_165571_2	1279009.ADICEAN_01691	2.038e-62	220.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,47KEA@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CSH2_k127_165571_0	700598.Niako_2069	2.415e-92	308.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1IQ3V@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CSH2_k127_1659199_1	883096.HMPREF9699_02028	6.823e-61	213.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1HYJ9@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CSH2_k127_1659199_0	246195.DNO_0078	3.478e-105	359.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0562,iYL1228.KPN_00477	ATP-grasp
CSH2_k127_1659199_2	1168289.AJKI01000063_gene3528	9.194e-07	55.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,2G1FZ@200643|Bacteroidia,3XKWZ@558415|Marinilabiliaceae	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
CSH2_k127_1669352_0	1408433.JHXV01000005_gene2228	1.936e-66	241.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,1HWZP@117743|Flavobacteriia,2PBJS@246874|Cryomorphaceae	976|Bacteroidetes	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
CSH2_k127_1669352_1	926562.Oweho_1468	1.817e-42	158.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia,2PB1G@246874|Cryomorphaceae	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
CSH2_k127_1683340_0	760192.Halhy_2468	1.27e-55	215.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
CSH2_k127_1683340_1	1121957.ATVL01000006_gene3301	1.316e-45	179.0	2DX8D@1|root,343UE@2|Bacteria,4P6Q1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1687160_0	1166018.FAES_0223	1.84e-05	48.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,47RCF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_170883_0	203124.Tery_4303	2.601e-08	67.0	COG3391@1|root,COG4932@1|root,COG5276@1|root,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Gram_pos_anchor,MucBP,SLH
CSH2_k127_1722384_0	1121895.Q765_08490	3.895e-22	111.0	COG4733@1|root,COG4733@2|Bacteria,4PPM5@976|Bacteroidetes,1IKQV@117743|Flavobacteriia,2P0UC@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CSH2_k127_1728622_0	880526.KE386488_gene998	3.84e-310	961.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,22U7M@171550|Rikenellaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CSH2_k127_1738472_0	391587.KAOT1_11967	5.827e-25	121.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I02G@117743|Flavobacteriia	976|Bacteroidetes	O	endonuclease I	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
CSH2_k127_1738472_1	313603.FB2170_15831	7.31e-17	94.0	COG2885@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,4NT1H@976|Bacteroidetes	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1738472_2	1296415.JACC01000043_gene84	5.437e-05	56.0	2DBQ3@1|root,2ZABU@2|Bacteria,4PNNE@976|Bacteroidetes	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
CSH2_k127_174429_0	468059.AUHA01000002_gene248	1.168e-204	647.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CSH2_k127_174429_1	1313421.JHBV01000027_gene1790	4.814e-16	87.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1746346_0	1356852.N008_11210	5.645e-57	207.0	COG0859@1|root,COG0859@2|Bacteria,4NMIH@976|Bacteroidetes,47MIW@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CSH2_k127_1746346_1	1408473.JHXO01000006_gene1132	3.245e-38	159.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
CSH2_k127_1758902_4	1127696.HMPREF9134_00003	1.764e-31	125.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,2FMFA@200643|Bacteroidia,22WUH@171551|Porphyromonadaceae	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CSH2_k127_1758902_3	925409.KI911562_gene1863	6.778e-51	188.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1IS2Z@117747|Sphingobacteriia	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CSH2_k127_1758902_1	1408433.JHXV01000009_gene1285	9.092e-66	237.0	COG3637@1|root,COG3637@2|Bacteria,4PJ16@976|Bacteroidetes,1ICQ3@117743|Flavobacteriia,2PBMQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1758902_0	1408433.JHXV01000001_gene732	3.163e-130	437.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,1IMQQ@117743|Flavobacteriia,2PBFK@246874|Cryomorphaceae	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CSH2_k127_1758902_2	1341155.FSS13T_04240	2.017e-53	195.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia,2NTCX@237|Flavobacterium	976|Bacteroidetes	FH	7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
CSH2_k127_1758902_5	929713.NIASO_20985	1.922e-25	109.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,1ISW1@117747|Sphingobacteriia	976|Bacteroidetes	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
CSH2_k127_1763140_1	706587.Desti_2715	7.102e-12	69.0	COG3829@1|root,COG3920@1|root,COG3829@2|Bacteria,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HWE_HK,HisKA_2,PAS_3,PAS_4,PAS_8,PAS_9
CSH2_k127_1763140_2	1185876.BN8_00854	7.775e-11	74.0	COG2885@1|root,COG2885@2|Bacteria,4NMTI@976|Bacteroidetes,47PC5@768503|Cytophagia	976|Bacteroidetes	M	GLEYA domain	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PA14
CSH2_k127_1763140_0	391587.KAOT1_21112	4.927e-44	168.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CSH2_k127_1768245_0	1408473.JHXO01000006_gene1161	1.598e-68	244.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,2FMTF@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
CSH2_k127_1768245_1	1484460.JSWG01000009_gene275	6.076e-40	162.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
CSH2_k127_1768245_2	290397.Adeh_4031	0.0001006	46.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,431ED@68525|delta/epsilon subdivisions,2WWZ0@28221|Deltaproteobacteria,2YVD5@29|Myxococcales	28221|Deltaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CSH2_k127_1778038_1	925409.KI911562_gene2646	2.488e-94	319.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CSH2_k127_1778038_0	880073.Calab_2100	1.997e-118	402.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CSH2_k127_178671_0	1300143.CCAV010000006_gene3996	5.294e-154	497.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia,3ZNY4@59732|Chryseobacterium	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
CSH2_k127_178671_1	1550091.JROE01000010_gene3248	2.11e-14	77.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CSH2_k127_1793144_1	1122179.KB890436_gene1412	0.000867	52.0	COG1361@1|root,COG3055@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,1IWYC@117747|Sphingobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Collagen_bind_2,DUF5060
CSH2_k127_1793144_0	1499967.BAYZ01000134_gene4	0.00026	50.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHAP,GBS_Bsp-like,Glyco_hydro_25,RicinB_lectin_2
CSH2_k127_1794361_0	946077.W5A_00735	1.205e-115	381.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IJAQ@117743|Flavobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CSH2_k127_1794361_3	313606.M23134_07467	4.305e-35	138.0	2AGNU@1|root,316WB@2|Bacteria,4NSNZ@976|Bacteroidetes,47RK1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1794361_1	755732.Fluta_1979	4.019e-89	309.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HY9H@117743|Flavobacteriia,2PASK@246874|Cryomorphaceae	976|Bacteroidetes	V	Beta-lactamase	nylB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CSH2_k127_1794361_2	929556.Solca_4113	4.063e-89	297.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1INNH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CSH2_k127_1802172_0	331678.Cphamn1_1563	6.045e-37	152.0	COG1680@1|root,COG1680@2|Bacteria,1FEZD@1090|Chlorobi	1090|Chlorobi	V	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
CSH2_k127_1802172_1	1120966.AUBU01000026_gene524	7.732e-22	102.0	COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes,47PRM@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_1805014_1	1341155.FSS13T_14950	4.687e-16	80.0	COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,1I24N@117743|Flavobacteriia,2NVXD@237|Flavobacterium	976|Bacteroidetes	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CSH2_k127_1805014_0	1408433.JHXV01000009_gene1331	0.0	1049.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1HY3C@117743|Flavobacteriia,2PA69@246874|Cryomorphaceae	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CSH2_k127_1807768_1	1168289.AJKI01000002_gene2324	7.33e-35	140.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,2FM3H@200643|Bacteroidia,3XIW8@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase (PrmA)	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
CSH2_k127_1807768_0	1227739.Hsw_0075	3.525e-90	310.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,47KBG@768503|Cytophagia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CSH2_k127_1807768_2	391598.FBBAL38_08724	3.825e-05	55.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,1HWX9@117743|Flavobacteriia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_1807983_0	1121896.JMLU01000002_gene526	9.906e-32	141.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4PPGH@976|Bacteroidetes,1IKM5@117743|Flavobacteriia,2NW1I@237|Flavobacterium	976|Bacteroidetes	O	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1834838_1	1239962.C943_03473	5.627e-55	199.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,47MHF@768503|Cytophagia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CSH2_k127_1834838_2	1078020.KEK_20598	2.672e-40	154.0	COG2077@1|root,COG2077@2|Bacteria,2II20@201174|Actinobacteria,233ZP@1762|Mycobacteriaceae	201174|Actinobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
CSH2_k127_1834838_0	1408433.JHXV01000001_gene1087	1.121e-150	484.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia,2PB53@246874|Cryomorphaceae	976|Bacteroidetes	F	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
CSH2_k127_1838534_0	1169144.KB910966_gene3437	2.11e-61	220.0	COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,1ZGCX@1386|Bacillus	91061|Bacilli	L	DNA alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CSH2_k127_1838534_1	1227739.Hsw_PA0072	3.357e-45	176.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CSH2_k127_1850398_2	1408433.JHXV01000034_gene46	2.267e-60	211.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1I1GI@117743|Flavobacteriia,2PAR0@246874|Cryomorphaceae	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CSH2_k127_1850398_1	1121899.Q764_08205	1.349e-85	287.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1HWWF@117743|Flavobacteriia,2NSMI@237|Flavobacterium	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CSH2_k127_1850398_0	1408433.JHXV01000034_gene48	2.082e-165	526.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia,2PA8U@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CSH2_k127_1850398_3	1121904.ARBP01000006_gene3819	1.782e-29	118.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,47PPE@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CSH2_k127_1857225_0	1313301.AUGC01000006_gene44	2.378e-225	714.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
CSH2_k127_1861233_1	485918.Cpin_2394	1.886e-50	191.0	COG3266@1|root,COG3266@2|Bacteria,4NKYH@976|Bacteroidetes	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1861233_0	929556.Solca_4330	3.313e-63	236.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1INUN@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_1865775_0	111780.Sta7437_2631	1.367e-176	568.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1GQBE@1117|Cyanobacteria,3VIKN@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Sulfotransfer_3
CSH2_k127_1865775_2	1144343.PMI41_02790	8.587e-12	68.0	COG0457@1|root,COG0457@2|Bacteria,1NA2B@1224|Proteobacteria,2UGJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
CSH2_k127_1865775_1	1185876.BN8_06081	1.453e-37	154.0	COG0457@1|root,COG0457@2|Bacteria,4NMCQ@976|Bacteroidetes,47KHK@768503|Cytophagia	976|Bacteroidetes	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
CSH2_k127_18680_1	1279009.ADICEAN_00755	8.662e-73	252.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CSH2_k127_18680_2	1408433.JHXV01000031_gene3210	3.34e-17	93.0	COG0457@1|root,COG0457@2|Bacteria,4PIM4@976|Bacteroidetes,1IMKJ@117743|Flavobacteriia,2PC1A@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CSH2_k127_18680_0	984262.SGRA_3562	3.332e-147	492.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CSH2_k127_1878266_0	1392490.JHZX01000001_gene869	1.409e-55	219.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_1879299_0	1408433.JHXV01000028_gene2153	3.358e-98	327.0	COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia	976|Bacteroidetes	P	Na H antiporter NhaD and related arsenite	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CSH2_k127_1879299_1	992406.RIA_1531	3.165e-72	249.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CSH2_k127_1879299_2	1121373.KB903623_gene2358	2.606e-68	235.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47K9J@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CSH2_k127_1885966_0	592029.DDD_0893	3.686e-189	596.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia,3HJZC@363408|Nonlabens	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, N-terminal domain	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_1885966_1	1396418.BATQ01000175_gene2794	4.871e-09	61.0	2DSKE@1|root,33GH9@2|Bacteria,46XPR@74201|Verrucomicrobia,2IWC4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_1893587_1	755732.Fluta_2846	6.94e-119	391.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1I8AX@117743|Flavobacteriia,2PAB3@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CSH2_k127_1893587_2	926549.KI421517_gene3596	5.008e-60	227.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
CSH2_k127_1893587_0	1121957.ATVL01000006_gene3150	2.276e-150	493.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CSH2_k127_1908725_0	889378.Spiaf_1292	1.523e-66	233.0	COG0566@1|root,COG0566@2|Bacteria,2JAFP@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CSH2_k127_1908725_1	153721.MYP_4845	1.196e-32	130.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,47V8W@768503|Cytophagia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CSH2_k127_1908725_2	1415778.JQMM01000001_gene1032	2.605e-17	90.0	COG0662@1|root,COG0662@2|Bacteria,1NEC3@1224|Proteobacteria,1SFFP@1236|Gammaproteobacteria,1JB7D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CSH2_k127_1908725_3	1227272.HMPREF1556_00065	1.419e-12	70.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,2FN5I@200643|Bacteroidia,22VZZ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CSH2_k127_1942470_1	1408433.JHXV01000028_gene2162	1.299e-62	218.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia,2PAI3@246874|Cryomorphaceae	976|Bacteroidetes	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CSH2_k127_1942470_0	1121373.KB903626_gene3282	4.566e-90	306.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CSH2_k127_1942470_2	485917.Phep_4102	2.704e-41	156.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,1IWJR@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_1978247_1	1123057.P872_15810	8.542e-43	169.0	COG0438@1|root,COG0438@2|Bacteria,4NNVW@976|Bacteroidetes,47TYE@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CSH2_k127_1978247_0	1279009.ADICEAN_01106	1.174e-119	399.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CSH2_k127_1978247_2	1123277.KB893217_gene4685	2.974e-24	113.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,47MXC@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CSH2_k127_1998672_0	1392490.JHZX01000001_gene869	1.343e-153	519.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_2012667_4	1286632.P278_19260	3.944e-15	76.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1I1A9@117743|Flavobacteriia	976|Bacteroidetes	I	hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
CSH2_k127_2012667_2	1121285.AUFK01000001_gene1965	1.307e-43	174.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia,3ZRSD@59732|Chryseobacterium	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CSH2_k127_2012667_0	700598.Niako_5074	7.722e-163	525.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CSH2_k127_2012667_1	755732.Fluta_0936	4.744e-60	215.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia,2PAX6@246874|Cryomorphaceae	976|Bacteroidetes	I	NUDIX domain	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
CSH2_k127_2012667_3	926562.Oweho_3542	5.216e-16	78.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1HXBH@117743|Flavobacteriia,2PAPZ@246874|Cryomorphaceae	976|Bacteroidetes	I	Squalene/phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
CSH2_k127_2052260_4	929556.Solca_4286	9.8e-15	83.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1IPS4@117747|Sphingobacteriia	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CSH2_k127_2052260_5	1408433.JHXV01000001_gene922	1.763e-09	64.0	2EVWW@1|root,33PAJ@2|Bacteria,4NZKD@976|Bacteroidetes,1ICSC@117743|Flavobacteriia,2PBZN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2052260_0	755732.Fluta_2237	7.977e-82	277.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1HX32@117743|Flavobacteriia,2PBNQ@246874|Cryomorphaceae	976|Bacteroidetes	F	Uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
CSH2_k127_2052260_2	1168034.FH5T_04905	1.805e-40	162.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,2FT4P@200643|Bacteroidia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CSH2_k127_2052260_1	313598.MED152_12384	1.442e-60	226.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia,3VV44@52959|Polaribacter	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2052260_3	1408324.JNJK01000002_gene3380	5.572e-33	138.0	COG2746@1|root,COG2746@2|Bacteria,1VD7S@1239|Firmicutes,24RTX@186801|Clostridia,27K26@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Aminoglycoside 3-N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Antibiotic_NAT
CSH2_k127_2073238_0	926562.Oweho_1845	1.219e-50	194.0	COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1I785@117743|Flavobacteriia,2PAYX@246874|Cryomorphaceae	976|Bacteroidetes	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
CSH2_k127_2073238_1	926562.Oweho_1846	8.548e-18	90.0	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,1ICMI@117743|Flavobacteriia,2PAUF@246874|Cryomorphaceae	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CSH2_k127_2082020_1	1408433.JHXV01000036_gene268	4.947e-17	89.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes,1IAKI@117743|Flavobacteriia,2PB7R@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2082020_0	641143.HMPREF9331_01171	5.05e-111	368.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,1EQSH@1016|Capnocytophaga	976|Bacteroidetes	S	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CSH2_k127_2085217_2	886379.AEWI01000030_gene298	1.748e-36	151.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,2FPS4@200643|Bacteroidia,3XJ68@558415|Marinilabiliaceae	976|Bacteroidetes	S	PASTA	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
CSH2_k127_2085217_0	1515615.HQ41_05635	1.144e-74	266.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,2FNMC@200643|Bacteroidia,22WV1@171551|Porphyromonadaceae	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CSH2_k127_2085217_1	926562.Oweho_1381	7.366e-57	205.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1I1CS@117743|Flavobacteriia,2PAUA@246874|Cryomorphaceae	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CSH2_k127_2090794_2	1120966.AUBU01000001_gene742	1.267e-08	61.0	28IFK@1|root,2Z8HB@2|Bacteria,4NH1P@976|Bacteroidetes,47NVI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2090794_0	153721.MYP_299	9.079e-152	504.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47NFW@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	pgtB	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA
CSH2_k127_2090794_1	1121904.ARBP01000024_gene6621	3.119e-32	140.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,4P2B2@976|Bacteroidetes,47QWM@768503|Cytophagia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CSH2_k127_2094318_0	1121904.ARBP01000005_gene4494	5.091e-101	351.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_210241_1	755732.Fluta_2937	5.524e-18	93.0	2BPRN@1|root,32IIX@2|Bacteria,4PEDZ@976|Bacteroidetes,1ICSQ@117743|Flavobacteriia,2PC0H@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_210241_0	1120968.AUBX01000009_gene452	3.442e-47	185.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,47KFS@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
CSH2_k127_2112577_2	195253.Syn6312_2760	3.495e-11	65.0	COG4634@1|root,COG4634@2|Bacteria,1GJHB@1117|Cyanobacteria,1H1T3@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2112577_1	671143.DAMO_0711	7.504e-29	116.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
CSH2_k127_2112577_0	509635.N824_18545	1.16e-257	806.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CSH2_k127_2137790_1	1227266.HMPREF1551_01525	1.467e-44	169.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia,1EQ40@1016|Capnocytophaga	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CSH2_k127_2137790_0	1166018.FAES_1251	7.057e-66	234.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CSH2_k127_2137790_3	1121904.ARBP01000009_gene4385	1.662e-21	104.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2137790_2	485918.Cpin_5464	4.722e-34	136.0	COG1225@1|root,COG2259@1|root,COG1225@2|Bacteria,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
CSH2_k127_214574_1	1469557.JSWF01000045_gene486	2.374e-13	84.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	htaA	-	3.4.21.72	ko:K01347	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3	-	-	CHU_C,HtaA
CSH2_k127_214574_0	1121396.KB892946_gene2917	3.367e-41	174.0	COG0823@1|root,COG3291@1|root,COG3591@1|root,COG4676@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3591@2|Bacteria,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	Germane,Gmad1
CSH2_k127_214574_2	1122176.KB903537_gene1646	1.54e-05	58.0	COG1404@1|root,COG3209@1|root,COG3227@1|root,COG3292@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3227@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	B_lectin,CHB_HEX_C_1,DUF5011,LRR_5,PPC,Peptidase_S8,Reg_prop,Reprolysin_5
CSH2_k127_2150010_3	1122176.KB903542_gene353	4.625e-06	57.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes	976|Bacteroidetes	M	sodium ion export across plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CSH2_k127_2150010_0	714943.Mucpa_3034	3.664e-100	331.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CSH2_k127_2150010_2	1346330.M472_07780	2.22e-07	62.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2150010_1	1121129.KB903359_gene2246	7.698e-50	182.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,2FN59@200643|Bacteroidia,22WGM@171551|Porphyromonadaceae	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CSH2_k127_2151553_1	701176.VIBRN418_14228	1.354e-27	124.0	COG0665@1|root,COG0665@2|Bacteria,1Q6SU@1224|Proteobacteria,1TJ32@1236|Gammaproteobacteria,1Y0EC@135623|Vibrionales	135623|Vibrionales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CSH2_k127_2151553_0	62928.azo3592	6.357e-51	193.0	COG1091@1|root,COG1091@2|Bacteria,1N237@1224|Proteobacteria,2VPV6@28216|Betaproteobacteria	28216|Betaproteobacteria	M	dTDP-4-dehydrorhamnose reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2151553_2	452652.KSE_39670	2.216e-24	116.0	COG1215@1|root,COG1215@2|Bacteria,2GKKV@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyltransferases involved in cell wall biogenesis	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CSH2_k127_2151553_3	469382.Hbor_17060	7.597e-18	86.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y7KB@28890|Euryarchaeota,23UIG@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_2172948_1	1408433.JHXV01000020_gene3501	1.131e-24	114.0	COG4372@1|root,COG4372@2|Bacteria,4PKE4@976|Bacteroidetes,1IKDW@117743|Flavobacteriia,2PBQB@246874|Cryomorphaceae	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2172948_0	1408473.JHXO01000001_gene2185	4.676e-60	216.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,2FP14@200643|Bacteroidia	976|Bacteroidetes	S	ComF family	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
CSH2_k127_2183623_0	761193.Runsl_5365	1.131e-86	297.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia	976|Bacteroidetes	S	CinA-like protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CSH2_k127_2183623_1	402612.FP0742	1.735e-73	254.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia,2NTPY@237|Flavobacterium	976|Bacteroidetes	FJ	tRNA hydroxylase	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CSH2_k127_2183623_2	1122176.KB903576_gene5010	1.896e-49	189.0	COG2133@1|root,COG4886@1|root,COG2133@2|Bacteria,COG4886@2|Bacteria,4NF0B@976|Bacteroidetes,1IVY8@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
CSH2_k127_2185962_0	755732.Fluta_1892	4.428e-167	542.0	COG1520@1|root,COG2312@1|root,COG4386@1|root,COG1520@2|Bacteria,COG2312@2|Bacteria,COG4386@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
CSH2_k127_2207572_0	1122225.AULQ01000002_gene658	1.097e-10	71.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CSH2_k127_2223563_1	385682.AFSL01000088_gene890	6.188e-66	231.0	COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,2FQYA@200643|Bacteroidia,3XIMD@558415|Marinilabiliaceae	976|Bacteroidetes	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
CSH2_k127_2223563_0	927658.AJUM01000047_gene2840	4.863e-78	268.0	COG3271@1|root,COG3271@2|Bacteria,4NN8E@976|Bacteroidetes,2G23E@200643|Bacteroidia,3XJE1@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
CSH2_k127_2223563_2	641143.HMPREF9331_00580	3.539e-27	113.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia,1ER9N@1016|Capnocytophaga	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CSH2_k127_2226097_0	880074.BARVI_02180	5.139e-142	473.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FP0Y@200643|Bacteroidia,22W6I@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CSH2_k127_2226097_1	555500.I215_00525	8.136e-59	207.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,1I1AE@117743|Flavobacteriia	976|Bacteroidetes	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
CSH2_k127_2237038_0	929713.NIASO_03165	1.791e-219	685.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,1INSE@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CSH2_k127_2237038_3	1254432.SCE1572_16810	3.441e-20	96.0	292FR@1|root,2ZPZX@2|Bacteria,1PBNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2237038_2	504472.Slin_0182	1.907e-28	128.0	2DN5F@1|root,32VNB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2237038_1	1123234.AUKI01000002_gene1793	2.554e-107	364.0	COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,1HYBI@117743|Flavobacteriia	976|Bacteroidetes	V	Na -driven multidrug efflux pump	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CSH2_k127_2259976_0	1122176.KB903598_gene4712	4.355e-87	311.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
CSH2_k127_2294054_2	1286632.P278_20360	5.21e-32	129.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1I3ZI@117743|Flavobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CSH2_k127_2294054_1	1408433.JHXV01000017_gene1566	8.376e-121	393.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1HXQR@117743|Flavobacteriia,2PAKP@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CSH2_k127_2294054_0	873513.HMPREF6485_0710	3.091e-145	463.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes,2FKZ7@200643|Bacteroidia	976|Bacteroidetes	G	COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
CSH2_k127_2305340_1	641526.ADIWIN_1528	4.277e-31	134.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CSH2_k127_2305340_0	709991.Odosp_0309	6.353e-103	353.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia,22XC3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CSH2_k127_2305340_2	1408433.JHXV01000038_gene2219	1.731e-24	108.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IEBF@117743|Flavobacteriia,2PB0Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CSH2_k127_234627_0	929562.Emtol_3709	5.424e-60	217.0	COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,47JNV@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
CSH2_k127_234627_1	1123278.KB893614_gene5283	5.162e-56	207.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,47K3H@768503|Cytophagia	976|Bacteroidetes	FP	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CSH2_k127_234627_2	1408473.JHXO01000006_gene1215	4.083e-22	96.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,2FMUF@200643|Bacteroidia	976|Bacteroidetes	CP	ABC transporter permease	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CSH2_k127_2346452_0	1121904.ARBP01000001_gene5529	5.691e-114	392.0	COG3203@1|root,COG3203@2|Bacteria,4PKUC@976|Bacteroidetes,47YNV@768503|Cytophagia	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_2346452_1	1123248.KB893331_gene3781	6.15e-36	142.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CSH2_k127_2349878_1	926569.ANT_27700	1.293e-59	208.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CSH2_k127_2349878_0	1191523.MROS_0957	1.236e-165	530.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CSH2_k127_2350936_1	487796.Flav2ADRAFT_1047	5.936e-69	238.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CSH2_k127_2350936_0	926569.ANT_04560	1.965e-80	276.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CSH2_k127_2350936_3	742817.HMPREF9449_01986	1.453e-22	107.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FU10@200643|Bacteroidia,231DT@171551|Porphyromonadaceae	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CSH2_k127_2350936_2	929556.Solca_0563	1.172e-40	158.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CSH2_k127_2355505_0	765420.OSCT_0991	4.508e-52	197.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi,377CS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CSH2_k127_2360542_0	1239962.C943_00665	7.208e-72	253.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,47KI4@768503|Cytophagia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CSH2_k127_2360542_1	1237149.C900_01627	1.263e-59	222.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CSH2_k127_2361374_1	1408433.JHXV01000001_gene865	6.04e-18	91.0	299NP@1|root,30URQ@2|Bacteria,4P9EY@976|Bacteroidetes,1IGC2@117743|Flavobacteriia,2PC5C@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2361374_0	1239962.C943_00361	2.503e-134	437.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47JT9@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_2364910_1	649349.Lbys_1458	2.666e-10	70.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,47KA3@768503|Cytophagia	976|Bacteroidetes	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CSH2_k127_2364910_0	1313421.JHBV01000043_gene2974	9.386e-41	161.0	COG1555@1|root,COG1555@2|Bacteria,4NUGB@976|Bacteroidetes,1J0F4@117747|Sphingobacteriia	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2364910_2	1121931.AUHG01000011_gene1655	1.759e-09	66.0	COG0563@1|root,COG0634@1|root,COG0563@2|Bacteria,COG0634@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
CSH2_k127_2376114_0	1124780.ANNU01000002_gene1575	5.879e-192	612.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
CSH2_k127_2376114_1	755732.Fluta_2284	3.87e-158	511.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia,2PAFK@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CSH2_k127_2381648_0	1270196.JCKI01000008_gene1534	3.798e-40	153.0	2DN31@1|root,32V8P@2|Bacteria,4NT9U@976|Bacteroidetes,1ITIG@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2381648_1	1122176.KB903553_gene3647	6.306e-16	82.0	2DN6W@1|root,32Z3V@2|Bacteria,4NV6A@976|Bacteroidetes,1IUQM@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2381648_2	1122179.KB890422_gene2194	5.452e-10	62.0	COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1ISGU@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2,TrmB
CSH2_k127_2384404_1	56780.SYN_02140	9.91e-96	316.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42PMA@68525|delta/epsilon subdivisions,2X5AR@28221|Deltaproteobacteria,2MRG6@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
CSH2_k127_2384404_0	177437.HRM2_16890	1.802e-209	663.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MIGI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM molybdopterin oxidoreductase	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CSH2_k127_2384404_2	1131462.DCF50_p1622	4.781e-87	293.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,260KC@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM formate dehydrogenase, alpha subunit	nuoG	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CSH2_k127_2398654_0	1042376.AFPK01000029_gene1604	3.371e-116	402.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia,40614@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2398654_1	926562.Oweho_0210	1.723e-06	55.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia,2PAR3@246874|Cryomorphaceae	976|Bacteroidetes	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CSH2_k127_2400733_2	1185876.BN8_06695	1.509e-44	164.0	COG3239@1|root,COG3239@2|Bacteria,4NHPQ@976|Bacteroidetes,47KXE@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CSH2_k127_2400733_0	1237149.C900_04390	7.572e-193	610.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CSH2_k127_2400733_4	643867.Ftrac_1189	1.858e-19	91.0	2DXSD@1|root,346A9@2|Bacteria,4P5K0@976|Bacteroidetes,47VQR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2400733_3	1270196.JCKI01000003_gene1889	7.946e-34	136.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
CSH2_k127_2400733_1	313606.M23134_01449	5.27e-90	302.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CSH2_k127_241991_5	743722.Sph21_1574	1.519e-18	98.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CSH2_k127_241991_2	641524.ADICYQ_5941	6.6e-58	217.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CSH2_k127_241991_4	880526.KE386488_gene1884	2.233e-47	177.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia,22UGW@171550|Rikenellaceae	976|Bacteroidetes	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CSH2_k127_241991_3	1380384.JADN01000003_gene361	1.705e-57	205.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CSH2_k127_241991_0	1408433.JHXV01000020_gene3546	1.288e-98	332.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1I8GR@117743|Flavobacteriia,2PAP2@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_241991_1	1408433.JHXV01000022_gene3142	2.056e-77	267.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2430164_0	1408433.JHXV01000038_gene2216	2.896e-124	410.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2PBI8@246874|Cryomorphaceae	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2430164_1	1270196.JCKI01000006_gene2530	4.843e-43	162.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPAI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
CSH2_k127_2432674_1	1353537.TP2_07860	2.152e-22	96.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2XNKW@285107|Thioclava	28211|Alphaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CSH2_k127_2432674_0	1168034.FH5T_09155	7.795e-160	522.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,2FM0W@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CSH2_k127_2432798_0	1122226.AUHX01000001_gene529	1.787e-121	396.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CSH2_k127_2432798_1	1120965.AUBV01000001_gene3273	2.256e-47	177.0	COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,47K0B@768503|Cytophagia	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CSH2_k127_2444609_1	1121904.ARBP01000001_gene5938	2.624e-63	229.0	COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47NKH@768503|Cytophagia	976|Bacteroidetes	T	PFAM histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CSH2_k127_2444609_0	1237149.C900_00873	2.77e-267	844.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,47YPN@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_2451425_0	1185876.BN8_05365	1.217e-118	400.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47NBF@768503|Cytophagia	976|Bacteroidetes	S	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CSH2_k127_2451425_2	755732.Fluta_1554	1.399e-64	226.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1HY16@117743|Flavobacteriia,2PAVC@246874|Cryomorphaceae	976|Bacteroidetes	C	Ferritin-like domain	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CSH2_k127_2451425_3	391598.FBBAL38_03525	1.472e-21	102.0	2CJ96@1|root,32S9H@2|Bacteria,4NTVR@976|Bacteroidetes,1I9EP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2451425_1	1267211.KI669560_gene2147	1.291e-72	253.0	COG1506@1|root,COG1506@2|Bacteria,4NGW1@976|Bacteroidetes,1J11I@117747|Sphingobacteriia	976|Bacteroidetes	E	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
CSH2_k127_2461469_1	1313421.JHBV01000031_gene1344	1.743e-58	214.0	COG0265@1|root,COG3209@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4PKT1@976|Bacteroidetes	976|Bacteroidetes	O	COG3209 Rhs family protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
CSH2_k127_2461469_0	1237149.C900_01880	3.648e-197	636.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,47KYC@768503|Cytophagia	976|Bacteroidetes	M	penicillin-binding protein 1C	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CSH2_k127_2473624_1	504472.Slin_6631	1.153e-57	211.0	COG3239@1|root,COG3239@2|Bacteria,4NHPQ@976|Bacteroidetes,47KXE@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CSH2_k127_2473624_2	865937.Gilli_1010	1.976e-53	198.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,1HX82@117743|Flavobacteriia,2P7AY@244698|Gillisia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_2473624_0	1121957.ATVL01000010_gene234	2.898e-82	284.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,47MIJ@768503|Cytophagia	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CSH2_k127_2473624_3	1237500.ANBA01000009_gene904	1.169e-05	57.0	arCOG06613@1|root,2Z7VT@2|Bacteria,2I8ZN@201174|Actinobacteria	201174|Actinobacteria	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
CSH2_k127_2480120_0	869213.JCM21142_183	5.665e-144	468.0	COG2361@1|root,COG2361@2|Bacteria,4PKES@976|Bacteroidetes	976|Bacteroidetes	S	Glycoside hydrolase 97	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
CSH2_k127_2490696_0	439235.Dalk_2161	0.0002703	51.0	COG1032@1|root,COG1032@2|Bacteria,1R52J@1224|Proteobacteria,42P9G@68525|delta/epsilon subdivisions,2WKFU@28221|Deltaproteobacteria,2MIVS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CSH2_k127_2521062_1	1121007.AUML01000026_gene1816	3.662e-23	115.0	COG2866@1|root,COG3227@1|root,COG3342@1|root,COG2866@2|Bacteria,COG3227@2|Bacteria,COG3342@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia,2YIPC@290174|Aquimarina	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,MAM,Peptidase_M14,Reprolysin_4,fn3
CSH2_k127_2521062_0	1122176.KB903551_gene4274	1.036e-99	349.0	COG3227@1|root,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.2.1.14	ko:K01183,ko:K20274	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000,ko01002	-	GH18	-	Big_3,ChW,DUF5011,Flg_new,PCMD,Peptidase_M43
CSH2_k127_2524884_1	714943.Mucpa_6111	5.406e-20	100.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1ISXE@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CSH2_k127_2524884_0	435591.BDI_0949	3.988e-80	284.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia,22WPY@171551|Porphyromonadaceae	976|Bacteroidetes	S	Von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CSH2_k127_2524884_2	1121129.KB903359_gene1255	1.375e-16	81.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,22XC0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CSH2_k127_2536672_0	755732.Fluta_2301	3.098e-159	507.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1HXIP@117743|Flavobacteriia,2PAG8@246874|Cryomorphaceae	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CSH2_k127_2536672_1	1089547.KB913013_gene1430	1.465e-49	189.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
CSH2_k127_2538338_0	1121889.AUDM01000012_gene1451	2.74e-59	217.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF1080,PKD,fn3
CSH2_k127_2538338_1	1227739.Hsw_PA0001	4.459e-21	107.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CSH2_k127_2551534_2	313606.M23134_03828	4.05e-57	206.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,47P8Z@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CSH2_k127_2551534_3	1408473.JHXO01000004_gene249	4.253e-47	177.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,2FTAA@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CSH2_k127_2551534_1	709991.Odosp_2556	1.896e-62	220.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,2FNWA@200643|Bacteroidia,22XMY@171551|Porphyromonadaceae	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CSH2_k127_2551534_0	445970.ALIPUT_00381	1.662e-70	248.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,2FPBF@200643|Bacteroidia,22V1R@171550|Rikenellaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CSH2_k127_2568535_0	1121904.ARBP01000018_gene2636	6.338e-168	539.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CSH2_k127_2568535_1	471854.Dfer_3969	1.163e-12	69.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
CSH2_k127_2571552_0	760192.Halhy_5329	2.197e-275	859.0	COG3383@1|root,COG3383@2|Bacteria,4PKV4@976|Bacteroidetes,1IX2V@117747|Sphingobacteriia	976|Bacteroidetes	C	TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type	hndD	-	1.12.1.3,1.17.1.9	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CSH2_k127_2574955_2	929556.Solca_4457	7.092e-12	71.0	2EM8X@1|root,33EY2@2|Bacteria,4NYIN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
CSH2_k127_2574955_0	1121012.AUKX01000012_gene2280	6.709e-83	284.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia,23H09@178469|Arenibacter	976|Bacteroidetes	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
CSH2_k127_2574955_1	1408433.JHXV01000011_gene2096	6.168e-61	233.0	COG2706@1|root,COG3291@1|root,COG3292@1|root,COG4733@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,COG3292@2|Bacteria,COG4733@2|Bacteria,4PMMT@976|Bacteroidetes,1IJV8@117743|Flavobacteriia,2PBPE@246874|Cryomorphaceae	976|Bacteroidetes	GT	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CSH2_k127_257593_1	452637.Oter_4162	1.681e-05	48.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia	74201|Verrucomicrobia	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CSH2_k127_257593_2	1408433.JHXV01000002_gene320	0.0004335	46.0	2ACM1@1|root,3127F@2|Bacteria,4PH2W@976|Bacteroidetes,1ICTY@117743|Flavobacteriia,2PC5T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_257593_3	1356852.N008_03430	0.0008887	51.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF1080,PKD,fn3
CSH2_k127_2587751_1	1121438.JNJA01000011_gene1799	2.219e-58	204.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,42PR0@68525|delta/epsilon subdivisions,2WMBK@28221|Deltaproteobacteria,2M8E3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
CSH2_k127_2587751_0	56780.SYN_02675	8.187e-270	838.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria,2MQAP@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CSH2_k127_2604945_1	926562.Oweho_1124	3.301e-28	113.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,2PA6I@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_2604945_0	1279009.ADICEAN_03871	1.137e-177	567.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_2604945_2	755732.Fluta_1194	3.64e-22	101.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,1HY17@117743|Flavobacteriia,2PBGU@246874|Cryomorphaceae	976|Bacteroidetes	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CSH2_k127_2609275_0	880071.Fleli_2310	1.773e-66	244.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,47Y1S@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2609275_1	1122179.KB890436_gene1412	7.368e-10	71.0	COG1361@1|root,COG3055@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,1IWYC@117747|Sphingobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Collagen_bind_2,DUF5060
CSH2_k127_2615354_1	880073.Calab_1226	4.015e-31	140.0	COG3391@1|root,COG4412@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	lppL	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2615354_0	485918.Cpin_6992	2.948e-39	165.0	COG2374@1|root,COG2374@2|Bacteria,4NHFV@976|Bacteroidetes	976|Bacteroidetes	O	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Exo_endo_phos
CSH2_k127_2618108_3	1313421.JHBV01000016_gene5460	5.086e-45	171.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1INZ0@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
CSH2_k127_2618108_2	926549.KI421517_gene3983	1.625e-64	230.0	COG0715@1|root,COG0715@2|Bacteria,4NETN@976|Bacteroidetes,47JG1@768503|Cytophagia	976|Bacteroidetes	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
CSH2_k127_2618108_0	1453500.AT05_10680	3.109e-180	569.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CSH2_k127_2618108_1	929703.KE386491_gene694	7.293e-175	554.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CSH2_k127_2632281_1	926549.KI421517_gene2207	8.871e-68	237.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,47MBP@768503|Cytophagia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
CSH2_k127_2632281_2	1047013.AQSP01000144_gene885	1.002e-10	72.0	2B2YN@1|root,31VJM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2632281_0	411479.BACUNI_02408	1.945e-119	391.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,4AK6B@815|Bacteroidaceae	976|Bacteroidetes	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CSH2_k127_2639344_0	1408433.JHXV01000018_gene3848	5.453e-165	554.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I7ZV@117743|Flavobacteriia,2PAMN@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
CSH2_k127_2639740_1	870187.Thini_0125	6.489e-40	162.0	COG0823@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG4932@1|root,COG0823@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,HemolysinCabind,LRR_5,SdrD_B
CSH2_k127_2639740_0	1550091.JROE01000005_gene2130	2.233e-52	190.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CSH2_k127_2643716_0	929703.KE386491_gene2769	2.963e-216	681.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CSH2_k127_2663252_0	1220534.B655_0979	2.181e-43	175.0	COG2203@1|root,arCOG02361@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg
CSH2_k127_2665213_1	643867.Ftrac_1588	3.164e-27	123.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
CSH2_k127_2665213_0	755732.Fluta_0377	2.372e-64	233.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia,2PAKB@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CSH2_k127_2669531_1	714943.Mucpa_3213	7.841e-57	213.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,1INPG@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2812 DNA polymerase III, gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
CSH2_k127_2669531_0	873517.HMPREF1977_2197	1.43e-110	369.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1HX73@117743|Flavobacteriia,1EQQJ@1016|Capnocytophaga	976|Bacteroidetes	F	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CSH2_k127_2673413_4	1123277.KB893187_gene2733	1.006e-05	55.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47JJK@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CSH2_k127_2673413_1	1356852.N008_04025	1.003e-71	268.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia	976|Bacteroidetes	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT,HEAT_2,Pro_isomerase
CSH2_k127_2673413_0	926562.Oweho_2220	5.226e-217	685.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1HXY4@117743|Flavobacteriia,2PABR@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
CSH2_k127_2673413_2	468059.AUHA01000002_gene377	1.674e-53	193.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CSH2_k127_2690706_0	880073.Calab_2100	1.897e-145	479.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CSH2_k127_2690706_1	1313421.JHBV01000031_gene1344	1.468e-43	167.0	COG0265@1|root,COG3209@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4PKT1@976|Bacteroidetes	976|Bacteroidetes	O	COG3209 Rhs family protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
CSH2_k127_2692055_1	1121373.KB903663_gene1207	2.596e-68	237.0	COG5285@1|root,COG5285@2|Bacteria,4NMHK@976|Bacteroidetes,47RPD@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CSH2_k127_2692055_0	929556.Solca_2919	3.234e-147	479.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CSH2_k127_2697817_1	1227739.Hsw_1171	6.224e-28	112.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,47KEP@768503|Cytophagia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CSH2_k127_2697817_0	762903.Pedsa_0132	3.382e-161	521.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CSH2_k127_2697817_2	760192.Halhy_1155	8.097e-13	73.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CSH2_k127_2701094_3	1166018.FAES_4213	7.088e-05	48.0	COG3503@1|root,COG3503@2|Bacteria,4NFAF@976|Bacteroidetes,47KPK@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CSH2_k127_2701094_0	1046627.BZARG_2387	3.155e-117	390.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1HX12@117743|Flavobacteriia	976|Bacteroidetes	EGP	major facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CSH2_k127_2701094_2	498848.TaqDRAFT_3126	4.514e-21	97.0	COG4634@1|root,COG4634@2|Bacteria,1WKGU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
CSH2_k127_2701094_1	1140.Synpcc7942_0533	7.789e-22	98.0	COG2442@1|root,COG2442@2|Bacteria,1G8BN@1117|Cyanobacteria,1H21P@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CSH2_k127_2701966_1	1121100.JCM6294_3346	7.599e-34	138.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae	976|Bacteroidetes	GK	Psort location Cytoplasmic, score 9.26	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CSH2_k127_2701966_0	1150600.ADIARSV_1842	1.304e-114	382.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IQCR@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
CSH2_k127_270251_2	926556.Echvi_2122	3.037e-36	145.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
CSH2_k127_270251_1	1121912.AUHD01000007_gene413	8.457e-73	254.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CSH2_k127_270251_0	1122605.KB893634_gene4241	1.02e-104	351.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CSH2_k127_2722502_2	1236976.JCM16418_3627	7.44e-34	136.0	COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,26UXR@186822|Paenibacillaceae	91061|Bacilli	GM	nucleoside-diphosphate sugar epimerase	M1-688	-	-	-	-	-	-	-	-	-	-	-	Epimerase,HIM1,NAD_binding_10
CSH2_k127_2722502_0	1124780.ANNU01000016_gene1825	3.162e-102	347.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,47MV0@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CSH2_k127_2722502_1	1408433.JHXV01000006_gene2725	1.517e-57	203.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia,2PAQC@246874|Cryomorphaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CSH2_k127_2729977_0	1121904.ARBP01000016_gene5289	8.207e-109	375.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CSH2_k127_2734806_0	1122176.KB903572_gene4836	3.549e-18	99.0	COG1361@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SprB
CSH2_k127_2751395_0	1453498.LG45_04760	2.231e-162	522.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1HY3T@117743|Flavobacteriia,2NT19@237|Flavobacterium	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CSH2_k127_2760712_0	926549.KI421517_gene3052	0.0	1024.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CSH2_k127_2772849_6	1322246.BN4_11207	5.448e-18	98.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CSH2_k127_2772849_5	1107311.Q767_02430	9.338e-19	100.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4PPGH@976|Bacteroidetes,1IKM5@117743|Flavobacteriia,2NW1I@237|Flavobacterium	976|Bacteroidetes	O	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2772849_0	743722.Sph21_0670	1.521e-178	580.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CSH2_k127_2772849_8	1172185.KB911516_gene2548	1.942e-05	54.0	COG2849@1|root,COG2849@2|Bacteria,2GV9D@201174|Actinobacteria,4G7IS@85025|Nocardiaceae	201174|Actinobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CSH2_k127_2772849_3	1089547.KB913013_gene4379	3.069e-118	389.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,47KFN@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CSH2_k127_2772849_2	1313301.AUGC01000001_gene1640	1.249e-128	419.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
CSH2_k127_2772849_4	667015.Bacsa_2794	1.304e-70	246.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,2FM5H@200643|Bacteroidia,4AM6P@815|Bacteroidaceae	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CSH2_k127_2772849_1	755732.Fluta_0923	6.412e-161	510.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia,2PA7J@246874|Cryomorphaceae	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CSH2_k127_2776726_2	926569.ANT_08380	5.443e-15	78.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CSH2_k127_2776726_1	926569.ANT_08390	1.717e-31	126.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CSH2_k127_2776726_0	379066.GAU_1651	1.469e-108	363.0	COG1009@1|root,COG1009@2|Bacteria,1ZSZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CSH2_k127_2784978_3	509635.N824_13980	9.036e-11	62.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IZWK@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CSH2_k127_2784978_0	755732.Fluta_1464	4.477e-165	531.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia,2PA8A@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CSH2_k127_2784978_2	926562.Oweho_2456	1.079e-106	364.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2PACQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CSH2_k127_2784978_1	929556.Solca_3240	6.473e-134	432.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CSH2_k127_2804402_0	1121957.ATVL01000014_gene1424	4.971e-15	89.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CSH2_k127_2808226_2	1296416.JACB01000001_gene3563	2.549e-12	72.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1I17F@117743|Flavobacteriia,2YIU1@290174|Aquimarina	976|Bacteroidetes	J	RimM N-terminal domain	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CSH2_k127_2808226_1	657309.BXY_05390	9.981e-57	205.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,4AN81@815|Bacteroidaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
CSH2_k127_2808226_0	1237149.C900_03765	2.623e-57	205.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47MT4@768503|Cytophagia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CSH2_k127_2813252_2	373994.Riv7116_2798	2.177e-12	68.0	COG3864@1|root,COG3864@2|Bacteria,1G20V@1117|Cyanobacteria,1HQNY@1161|Nostocales	1117|Cyanobacteria	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
CSH2_k127_2813252_1	1501268.EW14_1765	1.502e-21	99.0	2AH0G@1|root,3179B@2|Bacteria,1GIPU@1117|Cyanobacteria,1MNER@1212|Prochloraceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2813252_0	290318.Cvib_0122	2.539e-39	154.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_CoxE
CSH2_k127_2839873_2	1408433.JHXV01000005_gene2427	6.794e-25	115.0	2BUW8@1|root,32Q8B@2|Bacteria,4PBQS@976|Bacteroidetes,1ICQT@117743|Flavobacteriia,2PBTB@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2839873_1	1453500.AT05_06645	8.112e-26	114.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,1I1ZP@117743|Flavobacteriia	976|Bacteroidetes	L	DNA mismatch repair protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
CSH2_k127_2839873_4	1288963.ADIS_1392	1.186e-19	103.0	COG0810@1|root,COG1629@1|root,COG4219@1|root,COG0810@2|Bacteria,COG1629@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,47M7Q@768503|Cytophagia	976|Bacteroidetes	KMT	PFAM BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
CSH2_k127_2839873_0	1408813.AYMG01000037_gene53	1.607e-65	230.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,1ISBJ@117747|Sphingobacteriia	976|Bacteroidetes	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CSH2_k127_2839873_3	1048983.EL17_19015	4.941e-22	98.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
CSH2_k127_284694_1	1041826.FCOL_10810	1.146e-39	150.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1HX46@117743|Flavobacteriia,2NUYV@237|Flavobacterium	976|Bacteroidetes	M	peptidase	mepM_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CSH2_k127_284694_2	643867.Ftrac_2908	2.833e-21	102.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,47QJY@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CSH2_k127_284694_0	1089547.KB913013_gene3562	8.684e-133	426.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,47KEK@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
CSH2_k127_2866804_0	1313421.JHBV01000049_gene57	2.296e-48	193.0	COG2133@1|root,COG3209@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,CHU_C,Copper-bind,DUF1080,GSDH,PKD,SprB
CSH2_k127_2874149_0	1279009.ADICEAN_01177	6.616e-18	97.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
CSH2_k127_2884882_1	1313301.AUGC01000006_gene160	2.955e-26	112.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes	976|Bacteroidetes	I	Acyl-transferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CSH2_k127_2884882_2	1150600.ADIARSV_1156	1.696e-22	103.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1ITUB@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CSH2_k127_2884882_0	1122176.KB903534_gene2082	7.861e-160	519.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes	976|Bacteroidetes	O	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
CSH2_k127_2892316_2	1500259.JQLD01000014_gene1644	4.837e-17	83.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,4BD0J@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
CSH2_k127_2892316_0	1173029.JH980292_gene2224	8.014e-63	228.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria,1H8PU@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM UbiA prenyltransferase	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
CSH2_k127_2892316_1	1227739.Hsw_3254	1.069e-31	133.0	298PG@1|root,2ZVTY@2|Bacteria,4NP4F@976|Bacteroidetes,47PR6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2892316_3	1122179.KB890436_gene1406	1.861e-10	66.0	COG1836@1|root,COG1836@2|Bacteria,4NPN7@976|Bacteroidetes,1IUFQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
CSH2_k127_2896193_0	886379.AEWI01000032_gene2715	1.275e-72	265.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia,3XJGZ@558415|Marinilabiliaceae	976|Bacteroidetes	M	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
CSH2_k127_2896193_1	1197477.IA57_00015	2.326e-36	139.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_2905684_0	1453500.AT05_08315	1.127e-163	543.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2916365_0	700598.Niako_5173	2.212e-110	364.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1IZDH@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CSH2_k127_2916365_1	1408433.JHXV01000037_gene2550	1.981e-107	357.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,1HXY0@117743|Flavobacteriia,2PAMV@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CSH2_k127_2916365_2	929556.Solca_0902	1.409e-42	167.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1IR1T@117747|Sphingobacteriia	976|Bacteroidetes	CP	ABC-type Na efflux pump, permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CSH2_k127_2916365_3	1121957.ATVL01000008_gene4250	5.894e-08	54.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia	976|Bacteroidetes	CP	COGs COG1668 ABC-type Na efflux pump permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CSH2_k127_2917530_1	755732.Fluta_1664	1.899e-23	114.0	COG2246@1|root,COG2246@2|Bacteria,4P0AU@976|Bacteroidetes,1I7XA@117743|Flavobacteriia,2PBPM@246874|Cryomorphaceae	976|Bacteroidetes	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2917530_0	760192.Halhy_6389	5.567e-107	358.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1IQ87@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1131 ABC-type multidrug transport system ATPase component	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_2917530_2	1121898.Q766_04470	1.332e-08	57.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia,2NSI6@237|Flavobacterium	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CSH2_k127_2923601_1	1121904.ARBP01000015_gene149	2.89e-69	239.0	COG3000@1|root,COG3000@2|Bacteria,4NI60@976|Bacteroidetes,47N8J@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_2923601_0	391596.PBAL39_23562	6.215e-131	429.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1INY6@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CSH2_k127_2927067_1	926549.KI421517_gene3311	2.469e-42	174.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CSH2_k127_2927067_0	1237149.C900_05190	9.332e-45	171.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
CSH2_k127_2928817_0	63737.Npun_R6588	4.349e-169	552.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HQV2@1161|Nostocales	1117|Cyanobacteria	Q	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CSH2_k127_2929664_1	926562.Oweho_1092	4.237e-32	139.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2929664_0	926549.KI421517_gene1370	4.287e-93	313.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,47JF0@768503|Cytophagia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CSH2_k127_2929664_2	246197.MXAN_2876	5.004e-14	85.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WMM2@28221|Deltaproteobacteria,2Z1Q8@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2934466_0	1122176.KB903545_gene863	1.858e-80	281.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1IRS5@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
CSH2_k127_2934466_1	604331.AUHY01000043_gene2776	3.924e-12	76.0	2DQAI@1|root,335NH@2|Bacteria,1WMK5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2934466_2	880071.Fleli_1785	8.599e-10	68.0	2DBUB@1|root,2ZB53@2|Bacteria,4NMWS@976|Bacteroidetes,47R1T@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2936074_2	795666.MW7_0721	6.247e-07	53.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2VHT7@28216|Betaproteobacteria,1K0NU@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Transport permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CSH2_k127_2936074_0	1163407.UU7_09145	3.56e-56	204.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1X35Q@135614|Xanthomonadales	135614|Xanthomonadales	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CSH2_k127_2936074_1	56110.Oscil6304_5164	1e-51	203.0	COG1216@1|root,COG1216@2|Bacteria,1G705@1117|Cyanobacteria,1HC0T@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,RgpF
CSH2_k127_2936249_0	1042376.AFPK01000036_gene1846	1.383e-185	586.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1HWUS@117743|Flavobacteriia,4063E@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CSH2_k127_2936249_1	926562.Oweho_2664	2.115e-88	294.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1HYVV@117743|Flavobacteriia,2PAAP@246874|Cryomorphaceae	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CSH2_k127_2938660_1	1313421.JHBV01000049_gene58	2.959e-35	138.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1IPU4@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CSH2_k127_2938660_0	929556.Solca_1154	1.468e-212	667.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
CSH2_k127_2938660_2	290512.Paes_1453	6.255e-14	74.0	COG1943@1|root,COG1943@2|Bacteria,1FF47@1090|Chlorobi	1090|Chlorobi	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CSH2_k127_2957873_0	1408813.AYMG01000014_gene1686	2.575e-232	732.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CSH2_k127_2958589_1	1150600.ADIARSV_1490	7.204e-17	94.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_2958589_0	1434325.AZQN01000002_gene1177	1.209e-36	146.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K36@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CSH2_k127_2963623_1	1270196.JCKI01000001_gene3881	1.856e-100	331.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CSH2_k127_2963623_0	1121895.Q765_02680	7.448e-129	419.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia,2NTQ5@237|Flavobacterium	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CSH2_k127_2978845_1	1279009.ADICEAN_02065	1.317e-64	234.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47MFI@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CSH2_k127_2978845_0	1453500.AT05_05730	0.0	1076.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CSH2_k127_2985065_3	1408473.JHXO01000011_gene3155	6.561e-30	119.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,2FN91@200643|Bacteroidia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CSH2_k127_2985065_1	391603.FBALC1_16372	2.663e-93	318.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CSH2_k127_2985065_0	746697.Aeqsu_0599	6.629e-199	643.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1HXW2@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CSH2_k127_2985065_2	945713.IALB_0147	3.561e-79	280.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
CSH2_k127_2985065_4	272569.rrnB0071	2.212e-13	80.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CSH2_k127_2985497_0	755732.Fluta_0895	3.993e-295	915.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1HX0U@117743|Flavobacteriia,2PAC8@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CSH2_k127_2985497_2	1380370.JIBA01000012_gene3471	0.0004677	50.0	COG2314@1|root,COG2314@2|Bacteria,2GU27@201174|Actinobacteria,4FHWZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,TM2
CSH2_k127_2985497_1	1121896.JMLU01000005_gene2426	6.817e-105	345.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia,2NTCR@237|Flavobacterium	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CSH2_k127_299148_0	1408433.JHXV01000014_gene3680	9.643e-261	845.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IG7B@117743|Flavobacteriia,2PBE8@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_2992196_1	1279009.ADICEAN_03833	2.189e-148	488.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,47JAK@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CSH2_k127_2992196_2	411154.GFO_2762	5.113e-39	154.0	COG0221@1|root,COG0221@2|Bacteria,4NPTA@976|Bacteroidetes,1I2GY@117743|Flavobacteriia	976|Bacteroidetes	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CSH2_k127_2992196_0	445970.ALIPUT_01904	9.756e-151	481.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,2FNQK@200643|Bacteroidia,22V6X@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CSH2_k127_2995000_1	865937.Gilli_3169	2.522e-27	115.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,1HWR2@117743|Flavobacteriia,2P6EW@244698|Gillisia	976|Bacteroidetes	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CSH2_k127_2995000_0	1121129.KB903360_gene3346	2.766e-99	341.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,2FMXR@200643|Bacteroidia,22X1A@171551|Porphyromonadaceae	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CSH2_k127_3027897_2	755732.Fluta_1045	2.246e-10	68.0	2EQMK@1|root,30R0R@2|Bacteria,4PD8V@976|Bacteroidetes,1IFUG@117743|Flavobacteriia,2PC2A@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3027897_3	1189612.A33Q_1592	9.947e-05	54.0	2EV9H@1|root,33NQ6@2|Bacteria,4NZF1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3027897_1	1453500.AT05_11465	6.34e-65	225.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1I569@117743|Flavobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
CSH2_k127_3027897_0	1189612.A33Q_1594	1.01e-102	347.0	28N01@1|root,2ZB6M@2|Bacteria,4NFN1@976|Bacteroidetes,47NEE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3040342_2	558152.IQ37_08070	8.811e-16	79.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1I2XJ@117743|Flavobacteriia,3ZRSS@59732|Chryseobacterium	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CSH2_k127_3040342_1	1347342.BN863_7610	2.911e-71	245.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CSH2_k127_3040342_3	1123517.JOMR01000001_gene1241	0.0004736	50.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,460GM@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CSH2_k127_3040342_0	1250006.JHZZ01000001_gene2601	7.504e-108	364.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1HZ2V@117743|Flavobacteriia,3VWBD@52959|Polaribacter	976|Bacteroidetes	F	Amidohydrolase family	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CSH2_k127_3040342_4	760192.Halhy_0935	0.0008668	42.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1IQP4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM N-terminal double-transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
CSH2_k127_304655_0	1168289.AJKI01000063_gene3526	5.254e-74	256.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,2FN1C@200643|Bacteroidia,3XJHQ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_304655_1	1120951.AUBG01000007_gene37	5.637e-57	226.0	COG4935@1|root,COG4935@2|Bacteria,4NF3C@976|Bacteroidetes,1HWT9@117743|Flavobacteriia	976|Bacteroidetes	O	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Omp28
CSH2_k127_305082_0	313596.RB2501_01830	1.77e-65	241.0	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,1HWQE@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CSH2_k127_305082_1	1089547.KB913013_gene4561	1.656e-43	175.0	COG1404@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NPFV@976|Bacteroidetes	976|Bacteroidetes	MO	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_305082_2	1392489.JPOL01000002_gene3247	2.187e-06	55.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
CSH2_k127_3054935_1	880074.BARVI_06710	1.432e-64	225.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,2FMND@200643|Bacteroidia,22X87@171551|Porphyromonadaceae	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CSH2_k127_3054935_0	926562.Oweho_2825	1.812e-95	326.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1HWQM@117743|Flavobacteriia,2PAVJ@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CSH2_k127_3059243_3	886379.AEWI01000049_gene3206	1.051e-13	76.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,2G223@200643|Bacteroidia,3XJ24@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3059243_2	869213.JCM21142_3965	4e-15	81.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3059243_1	1267211.KI669560_gene410	6.838e-63	229.0	COG0524@1|root,COG0524@2|Bacteria,4PIYB@976|Bacteroidetes,1IYXP@117747|Sphingobacteriia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CSH2_k127_3059243_0	1123277.KB893174_gene6054	3.289e-91	303.0	COG2313@1|root,COG2313@2|Bacteria,4NKE0@976|Bacteroidetes,47UFW@768503|Cytophagia	976|Bacteroidetes	Q	Indigoidine synthase A like protein	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
CSH2_k127_3060566_2	755732.Fluta_2602	6.597e-18	91.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia,2PB38@246874|Cryomorphaceae	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
CSH2_k127_3060566_1	1239962.C943_00888	1.849e-24	109.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,47RAK@768503|Cytophagia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CSH2_k127_3060566_0	908612.HMPREF9720_1311	4.025e-107	352.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,2FMCF@200643|Bacteroidia,22UX6@171550|Rikenellaceae	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CSH2_k127_3063922_1	1317122.ATO12_18105	1.207e-26	112.0	COG3153@1|root,COG3153@2|Bacteria,4PMM1@976|Bacteroidetes,1IKUZ@117743|Flavobacteriia,2YI7Y@290174|Aquimarina	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CSH2_k127_3063922_2	1158292.JPOE01000005_gene997	1.526e-05	54.0	2CP7W@1|root,32MRP@2|Bacteria,1Q5NY@1224|Proteobacteria,2VYCY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3063922_0	1408433.JHXV01000006_gene2768	3.148e-66	240.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
CSH2_k127_3064388_1	925409.KI911562_gene1163	6.238e-33	132.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1IPWT@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CSH2_k127_3064388_2	1499967.BAYZ01000013_gene6453	2.879e-23	111.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3064388_0	595460.RRSWK_05050	8.084e-63	228.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CSH2_k127_3071646_0	926562.Oweho_0933	7.109e-232	725.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HXQY@117743|Flavobacteriia,2PAKK@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM ATP-binding cassette protein, ChvD family	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
CSH2_k127_3098226_0	696281.Desru_1792	9.688e-124	406.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,261AH@186807|Peptococcaceae	186801|Clostridia	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
CSH2_k127_3098226_1	546414.Deide_03860	0.0005168	51.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1WJ6M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B,Lactamase_B_2
CSH2_k127_3098690_2	237368.SCABRO_00336	3.463e-07	54.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CSH2_k127_3098690_1	706587.Desti_4215	4.523e-48	182.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CSH2_k127_3098690_0	546271.Selsp_0987	3.48e-61	219.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4H1YS@909932|Negativicutes	909932|Negativicutes	P	Phosphate transporter family protein	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CSH2_k127_3099489_2	1197477.IA57_01090	0.0002232	53.0	COG0308@1|root,COG2374@1|root,COG3291@1|root,COG4412@1|root,COG0308@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,F5_F8_type_C,Peptidase_M1
CSH2_k127_3099489_0	1123037.AUDE01000012_gene106	1.072e-18	98.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3099489_1	945713.IALB_2577	8.07e-10	70.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
CSH2_k127_3099832_1	755732.Fluta_1911	2.52e-120	419.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1I8HX@117743|Flavobacteriia,2PAB4@246874|Cryomorphaceae	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
CSH2_k127_3099832_0	755732.Fluta_1913	6.254e-152	486.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia,2PAC1@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CSH2_k127_3099832_2	869213.JCM21142_1647	2.421e-59	214.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CSH2_k127_3099832_3	867902.Ornrh_1990	2.137e-41	165.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CSH2_k127_3099832_4	385682.AFSL01000054_gene452	5.383e-27	114.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia,3XIIJ@558415|Marinilabiliaceae	976|Bacteroidetes	J	Anticodon-binding domain of tRNA	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CSH2_k127_3103008_0	1313421.JHBV01000003_gene641	1.847e-79	277.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CSH2_k127_3103008_2	880071.Fleli_2837	4.347e-13	78.0	2AFVR@1|root,315YE@2|Bacteria,4PK8B@976|Bacteroidetes,47SSJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3103008_1	880071.Fleli_2836	1.574e-16	87.0	COG0584@1|root,COG0584@2|Bacteria,4NUR0@976|Bacteroidetes,47S2Q@768503|Cytophagia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CSH2_k127_3109666_0	1123248.KB893321_gene465	3.1e-144	473.0	COG2133@1|root,COG3291@1|root,COG3391@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NF7B@976|Bacteroidetes,1IWJV@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
CSH2_k127_3113180_0	1123277.KB893184_gene4186	1.136e-208	658.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CSH2_k127_3113180_1	1120966.AUBU01000010_gene2822	2.034e-53	192.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CSH2_k127_3120038_0	755732.Fluta_2594	1.647e-102	338.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia,2PAIE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CSH2_k127_3120038_2	1046627.BZARG_131	0.0003354	48.0	2CT98@1|root,32SSW@2|Bacteria,4NSGA@976|Bacteroidetes,1I40N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
CSH2_k127_3120038_1	1233950.IW22_14370	6.819e-20	96.0	2E4AP@1|root,32Z6C@2|Bacteria,4NWDP@976|Bacteroidetes,1I55P@117743|Flavobacteriia,3ZRMH@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_312713_0	1408433.JHXV01000022_gene3142	9.994e-183	587.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3132910_1	1313304.CALK_2337	1.922e-11	65.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	vioA	GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771	2.6.1.33	ko:K13308,ko:K20429	ko00523,ko01130,map00523,map01130	M00797	R02773	RC00006,RC00781	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
CSH2_k127_3132910_0	1178482.BJB45_10395	3.95e-84	296.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1S3F2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Orn DAP Arg decarboxylase	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CSH2_k127_3160498_2	700598.Niako_1953	1.46e-07	65.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_3160498_0	1121920.AUAU01000009_gene1881	1.106e-73	279.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
CSH2_k127_3160498_1	1356852.N008_05785	3.719e-11	77.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
CSH2_k127_3177070_1	1305737.JAFX01000001_gene1441	1.654e-22	109.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes	976|Bacteroidetes	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,SprB
CSH2_k127_3177070_2	1218108.KB908294_gene2130	0.0005285	46.0	2E6UP@1|root,331EC@2|Bacteria,4NUYV@976|Bacteroidetes,1I59A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3177070_0	926562.Oweho_2057	3.578e-104	347.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,1HXNZ@117743|Flavobacteriia,2PAJP@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CSH2_k127_3184560_0	1120966.AUBU01000026_gene524	1.076e-101	349.0	COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes,47PRM@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_3184681_0	1408433.JHXV01000018_gene3795	1.341e-196	647.0	COG0265@1|root,COG3673@1|root,COG4412@1|root,COG0265@2|Bacteria,COG3673@2|Bacteria,COG4412@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2PA7S@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
CSH2_k127_3191140_0	1279009.ADICEAN_00750	1.752e-32	131.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
CSH2_k127_3191140_1	1123008.KB905693_gene1374	5.053e-23	109.0	2CZWI@1|root,32T79@2|Bacteria,4NSNW@976|Bacteroidetes,2FTY4@200643|Bacteroidia,22YDH@171551|Porphyromonadaceae	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3191140_2	1384056.N787_12480	1.331e-10	68.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1X5VS@135614|Xanthomonadales	135614|Xanthomonadales	T	two-component system sensor-response regulator hybrid protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
CSH2_k127_3192298_1	1122176.KB903565_gene3200	1.241e-29	130.0	COG0308@1|root,COG0308@2|Bacteria,4P1D6@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_3192298_0	1270196.JCKI01000007_gene2372	2.725e-102	344.0	COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,1IR7C@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
CSH2_k127_322014_4	1122176.KB903551_gene4218	9.809e-15	74.0	COG2114@1|root,COG3292@1|root,COG2114@2|Bacteria,COG3292@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HNOBA,Reg_prop,Response_reg,Y_Y_Y
CSH2_k127_322014_2	313606.M23134_06670	1.413e-37	145.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
CSH2_k127_322014_3	1121875.KB907546_gene2464	7.467e-22	95.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia	976|Bacteroidetes	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CSH2_k127_322014_0	1408433.JHXV01000005_gene2329	7.848e-258	806.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,1HXR5@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CSH2_k127_322014_1	1229487.AMYW01000001_gene4048	2.841e-39	149.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,1I4E1@117743|Flavobacteriia,2NWPM@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CSH2_k127_322014_5	1089550.ATTH01000001_gene1148	1.051e-07	57.0	COG1523@1|root,COG4733@1|root,COG1523@2|Bacteria,COG4733@2|Bacteria,4NHA4@976|Bacteroidetes,1FIRB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48,FlgD_ig
CSH2_k127_3227118_1	1123508.JH636450_gene7226	7.231e-63	219.0	COG1607@1|root,COG1607@2|Bacteria,2J16W@203682|Planctomycetes	203682|Planctomycetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CSH2_k127_3227118_2	1121957.ATVL01000006_gene2691	8.942e-50	181.0	COG1666@1|root,COG1666@2|Bacteria,4NMBZ@976|Bacteroidetes,47Q82@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
CSH2_k127_3227118_0	485918.Cpin_6049	1.445e-71	248.0	COG0229@1|root,COG0229@2|Bacteria,4NP9M@976|Bacteroidetes,1J0CH@117747|Sphingobacteriia	976|Bacteroidetes	O	SelR domain	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CSH2_k127_3227118_3	1122179.KB890436_gene1412	5.569e-24	108.0	COG1361@1|root,COG3055@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,1IWYC@117747|Sphingobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Collagen_bind_2,DUF5060
CSH2_k127_3234282_0	926562.Oweho_1851	3.657e-09	70.0	COG3420@1|root,COG3420@2|Bacteria,4PPAE@976|Bacteroidetes,1IKH4@117743|Flavobacteriia,2PBVP@246874|Cryomorphaceae	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CSH2_k127_3234282_1	1284352.AOIG01000026_gene489	1.353e-07	64.0	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
CSH2_k127_3255935_0	1089547.KB913013_gene2676	1.896e-94	319.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,47Y82@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_3255935_1	1406840.Q763_06005	1.525e-11	76.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I02G@117743|Flavobacteriia,2NV5H@237|Flavobacterium	976|Bacteroidetes	O	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
CSH2_k127_3258485_0	153721.MYP_4140	1.475e-165	545.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,47JSW@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
CSH2_k127_3264475_1	1118235.CAJH01000009_gene592	9.157e-43	167.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,1RMC1@1236|Gammaproteobacteria,1XCQ4@135614|Xanthomonadales	135614|Xanthomonadales	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
CSH2_k127_3264475_0	1233950.IW22_11260	6.62e-116	394.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,1HX95@117743|Flavobacteriia,3ZPG6@59732|Chryseobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CSH2_k127_3269426_0	755732.Fluta_2021	1.074e-64	245.0	COG3291@1|root,COG3291@2|Bacteria,4PFQY@976|Bacteroidetes,1ICPB@117743|Flavobacteriia,2PBH6@246874|Cryomorphaceae	976|Bacteroidetes	S	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta
CSH2_k127_3274899_1	240292.Ava_1100	1.311e-23	110.0	COG1503@1|root,COG1503@2|Bacteria,1G2ER@1117|Cyanobacteria,1HS19@1161|Nostocales	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3274899_2	688270.Celal_3310	5.063e-15	81.0	COG1512@1|root,COG1512@2|Bacteria,4NS9C@976|Bacteroidetes,1I3XE@117743|Flavobacteriia,1F9JM@104264|Cellulophaga	976|Bacteroidetes	S	COGs COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CSH2_k127_3274899_0	1123248.KB893331_gene3789	1.633e-54	196.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1IREV@117747|Sphingobacteriia	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
CSH2_k127_3284779_2	1434325.AZQN01000007_gene3167	7.006e-43	159.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,47QNZ@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CSH2_k127_3284779_1	1501391.LG35_06510	6.563e-67	241.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,2FP2H@200643|Bacteroidia,22UDC@171550|Rikenellaceae	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CSH2_k127_3284779_0	1122621.ATZA01000004_gene1203	1.855e-155	512.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CSH2_k127_3285067_0	1123277.KB893244_gene5131	4.153e-129	421.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,47U25@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
CSH2_k127_3285067_1	1453500.AT05_02205	4.078e-60	218.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	pelE	-	3.4.11.10,3.4.11.6,4.2.2.2	ko:K01728,ko:K19701	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_2,CBM_6,Pec_lyase,Prenyltrans
CSH2_k127_329753_3	468059.AUHA01000005_gene2435	2.604e-54	196.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CSH2_k127_329753_0	1123277.KB893184_gene4194	3.705e-125	410.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,47PB1@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
CSH2_k127_329753_2	883096.HMPREF9699_00621	1.524e-69	244.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia	976|Bacteroidetes	S	transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CSH2_k127_329753_1	1288963.ADIS_3392	1.534e-84	284.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CSH2_k127_329753_4	1492737.FEM08_36390	1.038e-32	132.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I3YN@117743|Flavobacteriia,2NWJ9@237|Flavobacterium	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CSH2_k127_3300166_0	694427.Palpr_1114	1.627e-22	112.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,2FV1K@200643|Bacteroidia,22Z9F@171551|Porphyromonadaceae	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,YceI
CSH2_k127_3300166_1	1123277.KB893191_gene2895	6.455e-15	79.0	2DBH5@1|root,2Z97Q@2|Bacteria,4NK7F@976|Bacteroidetes,47YKW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3320091_1	509635.N824_06575	9.272e-73	252.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CSH2_k127_3320091_0	468059.AUHA01000003_gene1874	8.779e-127	411.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IPCD@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_3326348_0	1408433.JHXV01000014_gene3668	0.0	1663.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CSH2_k127_3327771_1	697282.Mettu_4065	1.618e-27	115.0	2E373@1|root,32ZYW@2|Bacteria,1P98F@1224|Proteobacteria,1SW8T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3327771_2	1035197.HMPREF9999_01951	0.0006154	51.0	COG1615@1|root,COG4206@1|root,COG1615@2|Bacteria,COG4206@2|Bacteria,4P008@976|Bacteroidetes,2FR6W@200643|Bacteroidia	976|Bacteroidetes	H	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3
CSH2_k127_3327771_0	925409.KI911562_gene2270	1.828e-81	281.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1IPC6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CSH2_k127_3328873_1	575615.HMPREF0670_00907	2.034e-17	85.0	COG3942@1|root,COG3942@2|Bacteria,4NKM5@976|Bacteroidetes,2FY10@200643|Bacteroidia	976|Bacteroidetes	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
CSH2_k127_3328873_0	929556.Solca_1919	6.256e-193	608.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1IRNQ@117747|Sphingobacteriia	976|Bacteroidetes	F	Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CSH2_k127_3352806_0	926549.KI421517_gene2705	1.834e-42	163.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,47QH7@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
CSH2_k127_3352806_1	1121373.KB903621_gene1893	2.013e-30	133.0	COG1807@1|root,COG1807@2|Bacteria,4P3UD@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3352830_0	439235.Dalk_2983	2.27e-73	256.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria,2MHQX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
CSH2_k127_3352830_1	644282.Deba_0774	1.572e-64	228.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CSH2_k127_3368506_0	1124780.ANNU01000045_gene2322	5.208e-65	228.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47JHZ@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CSH2_k127_3368506_1	118168.MC7420_3750	4.376e-58	213.0	COG1572@1|root,COG2931@1|root,COG3291@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1GBUS@1117|Cyanobacteria,1HEVI@1150|Oscillatoriales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,HemolysinCabind
CSH2_k127_3376252_1	1453498.LG45_06340	3.437e-59	208.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia,2NUAF@237|Flavobacterium	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CSH2_k127_3376252_0	391598.FBBAL38_03835	2.74e-208	658.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CSH2_k127_3376252_2	1453500.AT05_01715	7.215e-36	144.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
CSH2_k127_3391221_1	266748.HY04_06725	8.381e-82	273.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia,3ZPFP@59732|Chryseobacterium	976|Bacteroidetes	C	CoB--CoM heterodisulfide reductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CSH2_k127_3391221_0	1313421.JHBV01000003_gene659	0.0	1249.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IRKC@117747|Sphingobacteriia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CSH2_k127_3391221_2	1123037.AUDE01000032_gene2255	4.694e-05	49.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3392742_2	991.IW20_20425	8.973e-16	82.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,1HYYV@117743|Flavobacteriia,2NSPI@237|Flavobacterium	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CSH2_k127_3392742_0	1163408.UU9_00969	7.509e-53	192.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1X69P@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CSH2_k127_3392742_1	1107311.Q767_01615	2.63e-39	164.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
CSH2_k127_3398361_5	1121897.AUGO01000001_gene1257	1.263e-06	58.0	COG2608@1|root,COG2608@2|Bacteria,4NS2K@976|Bacteroidetes,1I3FW@117743|Flavobacteriia,2NWRM@237|Flavobacterium	976|Bacteroidetes	P	heavy metal	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
CSH2_k127_3398361_4	1356852.N008_07605	2.943e-60	219.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_3398361_2	761193.Runsl_1666	1.596e-116	379.0	COG1216@1|root,COG1216@2|Bacteria,4PNB1@976|Bacteroidetes,47KU6@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_3398361_0	760192.Halhy_6511	4.106e-156	510.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IUX1@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CSH2_k127_3398361_1	1185876.BN8_04640	1.007e-129	428.0	COG0626@1|root,COG0626@2|Bacteria,4NH38@976|Bacteroidetes,47K5I@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
CSH2_k127_3398361_3	1408433.JHXV01000028_gene2156	1.146e-104	361.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
CSH2_k127_3403391_1	1123276.KB893263_gene4630	1.039e-12	68.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,47JQE@768503|Cytophagia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CSH2_k127_3403391_0	1408433.JHXV01000012_gene3988	4.493e-118	397.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,1IMQS@117743|Flavobacteriia,2PBFS@246874|Cryomorphaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF5106)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
CSH2_k127_3411904_0	926562.Oweho_1753	1.952e-148	476.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia,2PAAG@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CSH2_k127_3411904_1	641524.ADICYQ_5674	1.115e-62	225.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CSH2_k127_3411904_2	1434325.AZQN01000002_gene1278	8.239e-20	104.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
CSH2_k127_3412012_1	1121007.AUML01000045_gene3629	6.852e-21	99.0	COG2356@1|root,COG2374@1|root,COG3227@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,COG3227@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia,2YHNZ@290174|Aquimarina	976|Bacteroidetes	EL	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Endonuclease_1,LTD,MAM,SprB,fn3
CSH2_k127_3412012_0	1121904.ARBP01000005_gene4622	9e-85	287.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
CSH2_k127_3412012_2	1356852.N008_11210	2.371e-07	57.0	COG0859@1|root,COG0859@2|Bacteria,4NMIH@976|Bacteroidetes,47MIW@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CSH2_k127_3431621_0	215803.DB30_4163	1.47e-09	69.0	COG2367@1|root,COG2367@2|Bacteria,1Q2UC@1224|Proteobacteria,438GK@68525|delta/epsilon subdivisions,2X3RE@28221|Deltaproteobacteria,2YWXF@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
CSH2_k127_3431621_1	509191.AEDB02000067_gene886	1.565e-09	68.0	COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,24B7W@186801|Clostridia,3WINT@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,DUF4214
CSH2_k127_3450476_0	927658.AJUM01000040_gene843	3.324e-99	328.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,2FN89@200643|Bacteroidia,3XJ6G@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal Proteins L2, C-terminal domain	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CSH2_k127_3450476_4	1501391.LG35_06725	1.08e-29	120.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,22VE2@171550|Rikenellaceae	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CSH2_k127_3450476_2	929703.KE386491_gene2511	2.329e-70	244.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,47J8V@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CSH2_k127_3450476_1	1168289.AJKI01000011_gene473	7.905e-87	291.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,2FMS5@200643|Bacteroidia,3XJXV@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CSH2_k127_3450476_3	755732.Fluta_0780	1.338e-53	189.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1I2VK@117743|Flavobacteriia,2PAXU@246874|Cryomorphaceae	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CSH2_k127_3450476_5	929713.NIASO_01390	2.128e-23	100.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_3450741_2	1173027.Mic7113_4249	2.335e-05	56.0	COG1434@1|root,COG1434@2|Bacteria,1G5MW@1117|Cyanobacteria,1HA5K@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CSH2_k127_3450741_1	1313301.AUGC01000016_gene860	2.012e-11	70.0	COG0457@1|root,COG0457@2|Bacteria,4PM5D@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_8
CSH2_k127_3450741_0	1123228.AUIH01000012_gene30	5.922e-51	185.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XI7S@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
CSH2_k127_3462350_1	1408433.JHXV01000030_gene1415	5.57e-56	208.0	COG3391@1|root,COG3391@2|Bacteria,4P12F@976|Bacteroidetes	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3462350_0	880073.Calab_1342	2.511e-72	259.0	COG2091@1|root,COG2091@2|Bacteria,2NQ9X@2323|unclassified Bacteria	2|Bacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CSH2_k127_3466143_1	908937.Prede_1080	1.271e-34	139.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia	976|Bacteroidetes	O	Trigger factor	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
CSH2_k127_3466143_0	1408433.JHXV01000015_gene1787	1.153e-99	342.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia,2PA79@246874|Cryomorphaceae	976|Bacteroidetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CSH2_k127_3466143_2	926562.Oweho_2902	1.763e-27	115.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
CSH2_k127_3482651_2	1408433.JHXV01000011_gene2093	1.466e-52	195.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
CSH2_k127_3482651_0	755732.Fluta_2300	3.05e-106	348.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia,2PA6J@246874|Cryomorphaceae	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CSH2_k127_3482651_1	926562.Oweho_2960	3.401e-79	270.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1HXIP@117743|Flavobacteriia,2PAG8@246874|Cryomorphaceae	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CSH2_k127_3520350_1	755732.Fluta_1778	4.427e-39	155.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI0B@976|Bacteroidetes,1IG7A@117743|Flavobacteriia,2PBJ3@246874|Cryomorphaceae	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_3520350_0	755732.Fluta_2899	1.377e-43	166.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CSH2_k127_3547030_0	1121007.AUML01000055_gene2942	4.233e-176	576.0	COG2931@1|root,COG4733@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,4PP90@976|Bacteroidetes,1IKGM@117743|Flavobacteriia,2YHK4@290174|Aquimarina	976|Bacteroidetes	Q	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,MAM,Peptidase_M36
CSH2_k127_356194_2	1121957.ATVL01000006_gene2617	0.0001312	47.0	COG2244@1|root,COG2244@2|Bacteria,4NRKF@976|Bacteroidetes,47XRY@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CSH2_k127_356194_1	1151117.AJLF01000001_gene1492	6.257e-22	108.0	arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
CSH2_k127_356194_0	1089547.KB913013_gene765	3.925e-81	276.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47K51@768503|Cytophagia	976|Bacteroidetes	S	PFAM GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CSH2_k127_3570830_0	755732.Fluta_2738	6.683e-215	674.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1HWVX@117743|Flavobacteriia,2PB6G@246874|Cryomorphaceae	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CSH2_k127_3570830_1	1122176.KB903561_gene3593	1.45e-97	326.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IXJN@117747|Sphingobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3572100_1	1121129.KB903360_gene3210	1.254e-81	276.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,2FM24@200643|Bacteroidia,22X5Z@171551|Porphyromonadaceae	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CSH2_k127_3572100_0	1168289.AJKI01000011_gene453	1.102e-165	533.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia,3XISD@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecY translocase	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CSH2_k127_3572100_2	1408433.JHXV01000034_gene42	7.174e-51	184.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1I17M@117743|Flavobacteriia,2PAU9@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CSH2_k127_3572100_3	1121904.ARBP01000006_gene3828	1.476e-13	73.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CSH2_k127_3576983_2	1150600.ADIARSV_2699	1.661e-09	67.0	COG1045@1|root,COG1045@2|Bacteria,4NVDC@976|Bacteroidetes,1ITAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640,ko:K03819	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
CSH2_k127_3576983_1	1484460.JSWG01000009_gene190	1.473e-47	187.0	COG1215@1|root,COG1215@2|Bacteria,4PNX4@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_35839_0	1166018.FAES_1638	1.417e-118	385.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,47KZ9@768503|Cytophagia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CSH2_k127_35839_1	643867.Ftrac_0204	0.0006186	51.0	COG0457@1|root,COG0457@2|Bacteria,4P3W9@976|Bacteroidetes,47VD9@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CSH2_k127_3591082_4	755732.Fluta_2548	2.523e-74	259.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia,2PA9N@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_3591082_2	111105.HR09_08950	1.129e-127	421.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,2FN92@200643|Bacteroidia,22WG2@171551|Porphyromonadaceae	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_3591082_0	929556.Solca_3491	3.22e-203	643.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IPN4@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_3591082_3	1168034.FH5T_20310	1.588e-89	307.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,2FQSQ@200643|Bacteroidia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CSH2_k127_3591082_1	1151061.CAJY01000017_gene250	8.486e-183	581.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA2	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CSH2_k127_3591082_5	111105.HR09_02395	1.304e-14	79.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,2FNG0@200643|Bacteroidia,22WUN@171551|Porphyromonadaceae	976|Bacteroidetes	U	Transporter, MotA TolQ ExbB proton channel family protein	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CSH2_k127_359113_0	1122176.KB903554_gene4021	1.229e-29	135.0	COG3210@1|root,COG3291@1|root,COG4935@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,DUF11,PKD,SprB
CSH2_k127_359113_2	760192.Halhy_4327	4.596e-07	63.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_359113_3	307480.IW16_16805	2.44e-06	60.0	COG2373@1|root,COG3291@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,3ZQD4@59732|Chryseobacterium	976|Bacteroidetes	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,SprB
CSH2_k127_359113_1	1157490.EL26_20165	1.806e-11	72.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CSH2_k127_3592257_1	1408433.JHXV01000002_gene458	1.782e-89	320.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2PBDK@246874|Cryomorphaceae	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3592257_0	929556.Solca_2750	2.575e-140	453.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IQAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CSH2_k127_3608385_1	755732.Fluta_3660	1.184e-25	112.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IMQP@117743|Flavobacteriia,2PBFH@246874|Cryomorphaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
CSH2_k127_3608385_0	714943.Mucpa_3996	3.08e-77	276.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CSH2_k127_3610320_3	1120951.AUBG01000020_gene1803	3.022e-31	124.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia	976|Bacteroidetes	E	asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
CSH2_k127_3610320_0	1121094.KB894644_gene2120	8.59e-58	206.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia,4AMZ9@815|Bacteroidaceae	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CSH2_k127_3610320_1	1408473.JHXO01000011_gene3035	6.378e-36	141.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
CSH2_k127_3610320_2	1211813.CAPH01000006_gene1548	4.634e-35	141.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,2FN0H@200643|Bacteroidia,22UF2@171550|Rikenellaceae	976|Bacteroidetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CSH2_k127_3612084_0	926562.Oweho_0559	4.222e-103	351.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1HXAN@117743|Flavobacteriia,2PBH1@246874|Cryomorphaceae	976|Bacteroidetes	L	DNA polymerase III subunits gamma and tau domain III	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CSH2_k127_3612084_1	28583.AMAG_04515T0	2.118e-49	180.0	COG0538@1|root,KOG1526@2759|Eukaryota,38CG3@33154|Opisthokonta,3NVZ4@4751|Fungi	4751|Fungi	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	IDP1	GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006102,GO:0006139,GO:0006520,GO:0006536,GO:0006537,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009060,GO:0009062,GO:0009064,GO:0009084,GO:0009117,GO:0009295,GO:0009987,GO:0015980,GO:0016042,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019395,GO:0019637,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0034440,GO:0034641,GO:0042579,GO:0042645,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0072350,GO:0072524,GO:1901360,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YLR174W,iND750.YLR174W	Iso_dh
CSH2_k127_3631143_0	760192.Halhy_0214	1.61e-97	339.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4PN79@976|Bacteroidetes	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_3631143_1	332101.JIBU02000084_gene4192	2.399e-50	204.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,36FCZ@31979|Clostridiaceae	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
CSH2_k127_3631143_2	641524.ADICYQ_1748	4.938e-23	112.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CSH2_k127_3631572_2	269798.CHU_1379	8.218e-113	367.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,47KBK@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CSH2_k127_3631572_3	485918.Cpin_7015	1.526e-61	217.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1IS1Q@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CSH2_k127_3631572_0	1408813.AYMG01000036_gene3284	5.897e-223	703.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CSH2_k127_3631572_1	755732.Fluta_1637	9.374e-136	447.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia,2PA4Y@246874|Cryomorphaceae	976|Bacteroidetes	S	PSP1 C-terminal conserved region	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
CSH2_k127_3631572_5	1168034.FH5T_08795	5.255e-28	120.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,2FUJF@200643|Bacteroidia	976|Bacteroidetes	S	Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
CSH2_k127_3631572_4	1453500.AT05_05780	3.108e-52	190.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia	976|Bacteroidetes	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CSH2_k127_3632194_3	338966.Ppro_1421	2.376e-14	77.0	COG0438@1|root,COG0438@2|Bacteria,1PFC7@1224|Proteobacteria,439Z9@68525|delta/epsilon subdivisions,2WWVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_3632194_1	1038859.AXAU01000036_gene4903	1.532e-72	260.0	COG0438@1|root,COG0438@2|Bacteria,1RJ6C@1224|Proteobacteria,2U50C@28211|Alphaproteobacteria,3K612@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_3632194_0	509635.N824_09100	2.319e-81	281.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
CSH2_k127_3632194_2	1408433.JHXV01000023_gene3302	1.237e-64	240.0	COG3291@1|root,COG3291@2|Bacteria,4PBW3@976|Bacteroidetes,1ICPP@117743|Flavobacteriia,2PBJ2@246874|Cryomorphaceae	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
CSH2_k127_364295_0	1313301.AUGC01000012_gene1352	1.118e-107	371.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes	976|Bacteroidetes	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CSH2_k127_364295_1	929562.Emtol_3822	2.747e-14	78.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3646893_1	1121129.KB903360_gene3560	7.723e-17	85.0	COG0399@1|root,COG0399@2|Bacteria,4NVFZ@976|Bacteroidetes,2FV56@200643|Bacteroidia,22YVB@171551|Porphyromonadaceae	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CSH2_k127_3646893_0	1237149.C900_03606	3.793e-88	297.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,47JS7@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CSH2_k127_3661568_0	1237149.C900_00739	5.939e-66	236.0	COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,47QPA@768503|Cytophagia	976|Bacteroidetes	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CSH2_k127_3664428_0	1168034.FH5T_18580	5.375e-64	248.0	COG1572@1|root,COG3210@1|root,COG4625@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria,4PN5X@976|Bacteroidetes	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CSH2_k127_3675130_2	1250232.JQNJ01000001_gene3085	6.976e-16	79.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1HX64@117743|Flavobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CSH2_k127_3675130_1	1218103.CIN01S_10_02310	2.964e-58	210.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1I1TP@117743|Flavobacteriia,3ZQNN@59732|Chryseobacterium	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
CSH2_k127_3675130_0	1288963.ADIS_3452	7.562e-61	221.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,47M73@768503|Cytophagia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CSH2_k127_3680234_1	1121896.JMLU01000031_gene2270	4.577e-141	453.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia,2NTTJ@237|Flavobacterium	976|Bacteroidetes	L	DNA Topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CSH2_k127_3680234_0	1317122.ATO12_01065	1.254e-209	667.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2YGYJ@290174|Aquimarina	976|Bacteroidetes	L	DNA Topoisomerase IV	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
CSH2_k127_368436_1	755732.Fluta_0667	5.766e-22	109.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_368436_0	1434325.AZQN01000006_gene3279	2.607e-54	213.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47KZC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CSH2_k127_3689980_0	1453500.AT05_09780	1.866e-197	626.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,1HWWY@117743|Flavobacteriia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3689980_2	760192.Halhy_4290	1.372e-23	114.0	2EBH5@1|root,335HP@2|Bacteria,4NW0F@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3689980_1	471857.Svir_06310	2.249e-55	202.0	COG1611@1|root,COG1611@2|Bacteria,2GMM1@201174|Actinobacteria,4E2JN@85010|Pseudonocardiales	201174|Actinobacteria	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Lysine_decarbox,NUDIX
CSH2_k127_3703556_1	595536.ADVE02000001_gene994	4.174e-29	126.0	COG4627@1|root,COG4627@2|Bacteria,1NKXY@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CSH2_k127_3703556_0	1121129.KB903360_gene3158	6.88e-107	359.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,2FPNI@200643|Bacteroidia,22XA0@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CSH2_k127_3704859_0	1501230.ET33_36095	5.871e-08	65.0	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
CSH2_k127_3707865_0	391587.KAOT1_11967	5.422e-09	68.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I02G@117743|Flavobacteriia	976|Bacteroidetes	O	endonuclease I	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
CSH2_k127_3707865_1	1121889.AUDM01000025_gene2	4.772e-07	62.0	COG2374@1|root,COG3209@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	TNT
CSH2_k127_3711182_1	755732.Fluta_0268	1.882e-88	296.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1HXC5@117743|Flavobacteriia,2PAKV@246874|Cryomorphaceae	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CSH2_k127_3711182_0	743722.Sph21_1542	1.435e-106	352.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CSH2_k127_3711182_2	1227739.Hsw_1886	8.708e-49	181.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,47PDC@768503|Cytophagia	976|Bacteroidetes	V	PFAM ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CSH2_k127_3730465_0	1408433.JHXV01000014_gene3668	9.486e-83	287.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
CSH2_k127_3730465_1	880526.KE386488_gene1161	1.619e-51	186.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia,22UFP@171550|Rikenellaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CSH2_k127_3730465_2	742817.HMPREF9449_02788	9.437e-08	57.0	COG5652@1|root,COG5652@2|Bacteria,4PA3X@976|Bacteroidetes,2FVHF@200643|Bacteroidia	976|Bacteroidetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CSH2_k127_3733870_0	1307759.JOMJ01000003_gene1527	8.448e-21	107.0	COG3920@1|root,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HWE_HK,HisKA_2,PAS_3,PAS_4,PAS_8,PAS_9
CSH2_k127_3740755_1	1166018.FAES_5169	2.477e-09	67.0	COG3291@1|root,COG3291@2|Bacteria,4NMA6@976|Bacteroidetes	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
CSH2_k127_3740755_0	471854.Dfer_5804	1.018e-79	286.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,47JW5@768503|Cytophagia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CSH2_k127_3747695_1	742725.HMPREF9450_00788	7.303e-31	124.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,2FMCI@200643|Bacteroidia,22V87@171550|Rikenellaceae	976|Bacteroidetes	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CSH2_k127_3747695_0	1107311.Q767_13120	4.552e-45	169.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia,2NWE0@237|Flavobacterium	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CSH2_k127_3747695_3	1450525.JATV01000002_gene2061	3.729e-13	76.0	COG2350@1|root,COG2350@2|Bacteria,4NR5W@976|Bacteroidetes,1I5PD@117743|Flavobacteriia,2NU9F@237|Flavobacterium	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3747695_2	502025.Hoch_5175	4.696e-28	117.0	COG0824@1|root,COG0824@2|Bacteria,1MZTU@1224|Proteobacteria,42WZM@68525|delta/epsilon subdivisions,2WT0J@28221|Deltaproteobacteria,2Z1TJ@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CSH2_k127_3764487_3	1279009.ADICEAN_00311	4.187e-11	68.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
CSH2_k127_3764487_2	1121033.AUCF01000042_gene2682	3.687e-21	97.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VEWH@28211|Alphaproteobacteria,2JZK5@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483,ko:K07774	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CSH2_k127_3764487_0	927658.AJUM01000034_gene263	3.334e-121	403.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,2FM5E@200643|Bacteroidia,3XIR2@558415|Marinilabiliaceae	976|Bacteroidetes	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CSH2_k127_3764487_1	1356852.N008_13100	3.602e-91	303.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CSH2_k127_3765170_0	414684.RC1_2704	4.781e-83	286.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2JQ6K@204441|Rhodospirillales	204441|Rhodospirillales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CSH2_k127_3765170_2	926559.JoomaDRAFT_1654	6.914e-30	127.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1I1EE@117743|Flavobacteriia	976|Bacteroidetes	S	gliding motility protein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3765170_1	313603.FB2170_07479	1.205e-40	153.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PGSB@252356|Maribacter	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CSH2_k127_3776645_1	755732.Fluta_1314	1.964e-29	129.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
CSH2_k127_3776645_0	1434325.AZQN01000011_gene3744	5.932e-81	281.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,47MRX@768503|Cytophagia	976|Bacteroidetes	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CSH2_k127_377746_0	1408433.JHXV01000002_gene467	2.065e-158	509.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1HWS1@117743|Flavobacteriia,2PAKC@246874|Cryomorphaceae	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CSH2_k127_377746_1	762903.Pedsa_1330	1.416e-105	349.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1IPF3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3781900_1	1122176.KB903587_gene4484	1.35e-92	321.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1IPRF@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CSH2_k127_3781900_2	742725.HMPREF9450_01793	4.306e-35	143.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,2FPFD@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
CSH2_k127_3781900_0	1227739.Hsw_2138	9.812e-93	309.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CSH2_k127_3792157_1	1356852.N008_19025	6.968e-31	123.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CSH2_k127_3792157_0	1168289.AJKI01000006_gene236	1.493e-111	390.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia,3XJ8E@558415|Marinilabiliaceae	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
CSH2_k127_3803315_0	1122176.KB903565_gene3321	1.602e-145	480.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_3804061_0	290397.Adeh_0206	4.713e-97	339.0	COG0477@1|root,COG0477@2|Bacteria,1NS3F@1224|Proteobacteria,42X52@68525|delta/epsilon subdivisions,2WUPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_3804061_1	760192.Halhy_1208	2.118e-62	227.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1INM7@117747|Sphingobacteriia	976|Bacteroidetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CSH2_k127_3804061_2	518766.Rmar_1416	6.266e-22	101.0	COG2410@1|root,COG2410@2|Bacteria,4NT6P@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
CSH2_k127_381010_1	861299.J421_3711	1.967e-47	175.0	COG1024@1|root,COG1024@2|Bacteria,1ZSTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CSH2_k127_381010_0	153721.MYP_2624	1.165e-72	258.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_381010_2	1124780.ANNU01000064_gene450	2.624e-13	70.0	COG3291@1|root,COG3291@2|Bacteria,4PHTU@976|Bacteroidetes,47P4N@768503|Cytophagia	976|Bacteroidetes	E	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_3819537_0	487796.Flav2ADRAFT_0642	8.332e-108	353.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CSH2_k127_3819537_2	926559.JoomaDRAFT_3568	8.109e-76	261.0	COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1HWKN@117743|Flavobacteriia	976|Bacteroidetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CSH2_k127_3819537_6	1158050.KB895470_gene2638	5.24e-18	90.0	COG3832@1|root,COG3832@2|Bacteria,2IKRU@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CSH2_k127_3819537_3	880071.Fleli_1917	9.32e-48	196.0	COG4421@1|root,COG4421@2|Bacteria,4NVD4@976|Bacteroidetes,47R51@768503|Cytophagia	976|Bacteroidetes	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
CSH2_k127_3819537_1	1121957.ATVL01000010_gene506	1.246e-86	294.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,47MMA@768503|Cytophagia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CSH2_k127_3819537_4	926549.KI421517_gene377	7.154e-43	164.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,47NTX@768503|Cytophagia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
CSH2_k127_3819537_5	1227739.Hsw_0356	7.335e-20	93.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,47Q1Y@768503|Cytophagia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
CSH2_k127_3827256_0	1380384.JADN01000009_gene146	1.737e-31	140.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RHS_repeat
CSH2_k127_3827256_1	313606.M23134_02987	1.772e-17	96.0	COG1044@1|root,COG1044@2|Bacteria,4NSYI@976|Bacteroidetes,47RJE@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3855737_0	313590.MED134_00570	5.599e-84	295.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,37DHI@326319|Dokdonia	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
CSH2_k127_3855737_2	236814.IX39_17060	8.227e-05	55.0	COG1523@1|root,COG3391@1|root,COG1523@2|Bacteria,COG3391@2|Bacteria,4NESV@976|Bacteroidetes,1HYX0@117743|Flavobacteriia	976|Bacteroidetes	G	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3855737_1	1122176.KB903540_gene98	2.172e-12	79.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,PKD,SprB
CSH2_k127_3859049_3	1434325.AZQN01000001_gene284	3.994e-38	145.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,47PV8@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
CSH2_k127_3859049_1	762903.Pedsa_2641	8.288e-68	243.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IRXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CSH2_k127_3859049_2	927658.AJUM01000022_gene995	1.578e-58	208.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,2FQJ0@200643|Bacteroidia,3XK0P@558415|Marinilabiliaceae	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CSH2_k127_3859049_4	1408433.JHXV01000042_gene1424	1.194e-36	139.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,1I42P@117743|Flavobacteriia,2PB54@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
CSH2_k127_3859049_0	743722.Sph21_0674	7.83e-179	572.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CSH2_k127_3863531_0	93059.P9211_07671	3.19e-71	268.0	28JA7@1|root,2Z951@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CSH2_k127_3877647_2	1313301.AUGC01000006_gene126	3.499e-76	282.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
CSH2_k127_3877647_3	755732.Fluta_1076	2.27e-50	188.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1ICNV@117743|Flavobacteriia,2PBDQ@246874|Cryomorphaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CSH2_k127_3877647_1	755732.Fluta_1076	2.852e-77	267.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1ICNV@117743|Flavobacteriia,2PBDQ@246874|Cryomorphaceae	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CSH2_k127_3877647_0	755732.Fluta_1910	2.171e-85	288.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia,2PAH6@246874|Cryomorphaceae	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CSH2_k127_3921799_0	1408433.JHXV01000001_gene996	2.42e-61	232.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia,2PA9P@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD/REP helicase N-terminal domain	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
CSH2_k127_3929980_0	760192.Halhy_3247	4.187e-58	209.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CSH2_k127_3929980_1	1270196.JCKI01000002_gene393	5.59e-40	152.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,1ITHM@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_3929980_2	1408473.JHXO01000010_gene3699	1.248e-38	148.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FPA0@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
CSH2_k127_3930915_1	926549.KI421517_gene2112	1.279e-49	190.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
CSH2_k127_3930915_0	760192.Halhy_6846	9.153e-134	442.0	COG3329@1|root,COG3329@2|Bacteria,4NIR4@976|Bacteroidetes,1IW46@117747|Sphingobacteriia	976|Bacteroidetes	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
CSH2_k127_3930915_3	755732.Fluta_3780	1.073e-43	168.0	COG0668@1|root,COG0668@2|Bacteria,4NMMB@976|Bacteroidetes,1I2BV@117743|Flavobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CSH2_k127_3930915_2	1122179.KB890421_gene2528	3.292e-45	172.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,1IT7A@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CSH2_k127_3930915_4	1239962.C943_02343	3.757e-26	109.0	COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,47KD2@768503|Cytophagia	976|Bacteroidetes	CE	Isocitrate dehydrogenase	-	-	1.1.1.42,1.1.1.85	ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CSH2_k127_3937641_0	938709.AUSH02000051_gene200	2.652e-56	219.0	COG1404@1|root,COG3291@1|root,COG3405@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SLH,SdrD_B
CSH2_k127_3942147_0	1279009.ADICEAN_00457	5.866e-123	403.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,47K3T@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CSH2_k127_3942147_2	794903.OPIT5_11735	1.397e-63	228.0	COG0500@1|root,COG0500@2|Bacteria,46V7N@74201|Verrucomicrobia,3K8BC@414999|Opitutae	414999|Opitutae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CSH2_k127_3942147_3	1123276.KB893267_gene5044	6.38e-28	118.0	COG1765@1|root,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,47QVZ@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Fer4_19,Hydrolase_4,OsmC
CSH2_k127_3942147_1	1267211.KI669560_gene2488	2.84e-74	253.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CSH2_k127_3966850_0	1166018.FAES_2889	3.323e-23	115.0	COG1361@1|root,COG2133@1|root,COG3291@1|root,COG1361@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,47QVQ@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
CSH2_k127_397664_0	927658.AJUM01000047_gene2778	6.496e-71	261.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,2G1ZT@200643|Bacteroidia,3XIMW@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_397664_1	616991.JPOO01000001_gene3994	4.298e-18	87.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia,23G9W@178469|Arenibacter	976|Bacteroidetes	J	Lysine methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CSH2_k127_3989606_4	1122179.KB890458_gene646	8.685e-10	72.0	COG3210@1|root,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	2|Bacteria	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Haemagg_act,He_PIG,RHS_repeat
CSH2_k127_3989606_1	1408433.JHXV01000020_gene3500	3.439e-100	332.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1HXNN@117743|Flavobacteriia,2PAAD@246874|Cryomorphaceae	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CSH2_k127_3989606_2	1453500.AT05_11130	9.265e-86	291.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CSH2_k127_3989606_3	1229276.DI53_0468	2.786e-46	174.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1IS5M@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
CSH2_k127_3989606_0	509635.N824_22530	6.762e-104	348.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1IV11@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CSH2_k127_3999660_0	700598.Niako_2785	4.22e-11	76.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CSH2_k127_4001720_0	1279009.ADICEAN_04209	7.121e-48	175.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CSH2_k127_4001720_1	1121352.JHZP01000006_gene1193	3.57e-35	145.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,2VKTT@28216|Betaproteobacteria,2KPW9@206351|Neisseriales	206351|Neisseriales	S	YigZ family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
CSH2_k127_4001720_2	1408433.JHXV01000010_gene590	4.346e-07	54.0	COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,1HWX9@117743|Flavobacteriia,2PBQY@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CSH2_k127_4009341_0	269798.CHU_0094	0.0	1083.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
CSH2_k127_4016144_0	941449.dsx2_0368	8.506e-143	467.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WJ85@28221|Deltaproteobacteria,2M8UI@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM membrane bound O-acyl transferase MBOAT	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
CSH2_k127_4028348_1	869213.JCM21142_282	5.739e-29	123.0	COG0823@1|root,COG3291@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,4P0F7@976|Bacteroidetes	976|Bacteroidetes	U	Cell envelope biogenesis protein OmpA	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
CSH2_k127_4028348_0	485918.Cpin_3624	2.832e-61	223.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1IP9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_4028348_2	1121957.ATVL01000009_gene1003	4.908e-20	104.0	COG3210@1|root,COG3291@1|root,COG3405@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria,4NIQS@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 8	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Glyco_hydro_8
CSH2_k127_4053416_2	313596.RB2501_08425	9.194e-40	151.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1I2Y7@117743|Flavobacteriia	976|Bacteroidetes	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CSH2_k127_4053416_1	1408433.JHXV01000001_gene671	3.117e-136	442.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1HWR0@117743|Flavobacteriia,2PA6F@246874|Cryomorphaceae	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CSH2_k127_4053416_3	743722.Sph21_1364	1.993e-17	95.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1ITFF@117747|Sphingobacteriia	976|Bacteroidetes	O	NifU-like domain	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
CSH2_k127_4053416_0	1121904.ARBP01000001_gene5646	4.053e-267	835.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,47KM5@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CSH2_k127_4055350_0	926562.Oweho_2803	2.994e-118	391.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1HWNN@117743|Flavobacteriia,2PAD0@246874|Cryomorphaceae	976|Bacteroidetes	E	Arginase family	fjo29	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CSH2_k127_4055350_1	1121015.N789_06550	5.113e-27	113.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1X3EQ@135614|Xanthomonadales	135614|Xanthomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
CSH2_k127_4056347_0	153721.MYP_4062	3.63e-56	209.0	COG4733@1|root,COG4733@2|Bacteria,4NF53@976|Bacteroidetes,47MWJ@768503|Cytophagia	976|Bacteroidetes	S	SPTR Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4056347_1	1123277.KB893191_gene2898	1.351e-43	183.0	COG0823@1|root,COG5492@1|root,COG0823@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,PD40,Pkinase
CSH2_k127_4059951_1	391596.PBAL39_25395	2.882e-46	170.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1INPY@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
CSH2_k127_4059951_0	595460.RRSWK_02087	2.618e-63	224.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CSH2_k127_4059951_3	715226.ABI_44790	0.0009687	42.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,2KGA9@204458|Caulobacterales	204458|Caulobacterales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CSH2_k127_4059951_2	1356852.N008_13930	0.0006682	51.0	2C85E@1|root,335NV@2|Bacteria,4NVTV@976|Bacteroidetes,47S04@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PCMD
CSH2_k127_4074297_0	927658.AJUM01000037_gene2023	5.798e-43	176.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia,3XJUS@558415|Marinilabiliaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
CSH2_k127_4074297_1	1408473.JHXO01000006_gene1138	2.187e-15	81.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,2FM02@200643|Bacteroidia	976|Bacteroidetes	MNU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
CSH2_k127_4077575_2	755732.Fluta_2422	4.44e-17	88.0	29BEQ@1|root,2ZYD2@2|Bacteria,4PD0R@976|Bacteroidetes,1ICRX@117743|Flavobacteriia,2PBXT@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4077575_0	760192.Halhy_5816	9.595e-104	349.0	COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,1IQ7F@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CSH2_k127_4077575_1	1227739.Hsw_0595	1.799e-37	147.0	COG1680@1|root,COG1680@2|Bacteria,4NGND@976|Bacteroidetes,47NA8@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CSH2_k127_4078036_0	1123276.KB893268_gene4922	4.024e-135	439.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia	976|Bacteroidetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CSH2_k127_4078036_1	1121957.ATVL01000011_gene3724	4.681e-123	409.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CSH2_k127_4078036_2	1197477.IA57_05305	5.829e-12	68.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,1HXAV@117743|Flavobacteriia	976|Bacteroidetes	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CSH2_k127_4092177_0	984262.SGRA_1724	1.096e-56	203.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
CSH2_k127_4092177_3	1089547.KB913013_gene124	3.223e-06	51.0	2EGC0@1|root,331VR@2|Bacteria,4NWM2@976|Bacteroidetes,47S8W@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4092177_1	682795.AciX8_0041	4.489e-20	96.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CSH2_k127_4092177_2	1227272.HMPREF1556_01176	1.389e-08	62.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,2FNBD@200643|Bacteroidia,22W4K@171551|Porphyromonadaceae	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CSH2_k127_4106288_1	1237149.C900_04530	1.964e-53	192.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CSH2_k127_4106288_0	926562.Oweho_3003	7.029e-104	351.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CSH2_k127_4107288_0	926560.KE387025_gene4070	4.123e-46	169.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CSH2_k127_4107288_1	1396141.BATP01000027_gene1078	1.699e-45	170.0	arCOG05203@1|root,31A0K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4107288_2	416591.Tlet_1391	1.115e-06	56.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4107288_3	1408433.JHXV01000015_gene1780	8.963e-05	47.0	COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,1HYX1@117743|Flavobacteriia,2PBCQ@246874|Cryomorphaceae	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,MaoC_dehydratas
CSH2_k127_4112068_1	1227739.Hsw_0324	1.119e-61	220.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,47JKP@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
CSH2_k127_4112068_0	445970.ALIPUT_02247	1.076e-80	274.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
CSH2_k127_4112068_3	1033732.CAHI01000009_gene1615	3.993e-05	54.0	COG3064@1|root,COG3827@1|root,COG3064@2|Bacteria,COG3827@2|Bacteria,4PKT6@976|Bacteroidetes,2G0XA@200643|Bacteroidia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4112068_2	755732.Fluta_1146	1.048e-43	171.0	COG2234@1|root,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia,2PBDE@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
CSH2_k127_4120743_1	926549.KI421517_gene4136	3.27e-41	157.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,47K9F@768503|Cytophagia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CSH2_k127_4120743_0	700598.Niako_6871	1.539e-111	381.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1IVXW@117747|Sphingobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CSH2_k127_4120743_2	997884.HMPREF1068_04388	4.644e-25	111.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,2FM72@200643|Bacteroidia,4AKT0@815|Bacteroidaceae	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CSH2_k127_4120743_3	56110.Oscil6304_5163	2.019e-08	59.0	COG3551@1|root,COG3551@2|Bacteria,1GKUR@1117|Cyanobacteria,1HEYB@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CSH2_k127_4123772_0	926562.Oweho_2316	2.556e-62	233.0	COG5305@1|root,COG5305@2|Bacteria,4PAK3@976|Bacteroidetes,1IMPV@117743|Flavobacteriia,2PAU3@246874|Cryomorphaceae	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CSH2_k127_4123772_1	883096.HMPREF9699_00147	3.54e-38	145.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1I191@117743|Flavobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CSH2_k127_4132751_1	1218103.CIN01S_09_04030	1.427e-10	74.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,3ZNH1@59732|Chryseobacterium	976|Bacteroidetes	S	Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,MAM,PKD,fn3
CSH2_k127_4132751_0	1122179.KB890433_gene4020	2.216e-26	125.0	COG0265@1|root,COG1572@1|root,COG3209@1|root,COG0265@2|Bacteria,COG1572@2|Bacteria,COG3209@2|Bacteria,4PKT1@976|Bacteroidetes	976|Bacteroidetes	O	COG3209 Rhs family protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
CSH2_k127_4134775_1	867902.Ornrh_0746	1.314e-161	525.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia	976|Bacteroidetes	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CSH2_k127_4134775_0	992406.RIA_0437	2.55e-164	526.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CSH2_k127_4136130_1	1123276.KB893252_gene3726	9.198e-27	112.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CSH2_k127_4136130_0	1267211.KI669560_gene865	3.227e-117	400.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IQIN@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CSH2_k127_414317_1	1408433.JHXV01000037_gene2580	3.868e-33	133.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia,2PB51@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
CSH2_k127_414317_0	1279009.ADICEAN_00976	6.949e-123	403.0	COG1236@1|root,COG1236@2|Bacteria,4NFN7@976|Bacteroidetes,47JDM@768503|Cytophagia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
CSH2_k127_414317_2	1123360.thalar_00740	4.251e-30	122.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,2TRQ9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
CSH2_k127_4154283_1	313596.RB2501_15554	4.474e-73	258.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia	976|Bacteroidetes	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CSH2_k127_4154283_2	1356852.N008_05425	1.523e-21	104.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CSH2_k127_4154283_0	926562.Oweho_2451	5.424e-92	316.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia,2PABC@246874|Cryomorphaceae	976|Bacteroidetes	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CSH2_k127_4162413_1	1408433.JHXV01000026_gene3021	2.378e-78	278.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,1HZPN@117743|Flavobacteriia,2PBIP@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CSH2_k127_4162413_0	1236518.BAKP01000045_gene2232	1.382e-85	290.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulatory protein	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CSH2_k127_4162413_2	1121957.ATVL01000006_gene2766	2.185e-21	109.0	COG3291@1|root,COG3291@2|Bacteria,4NJHV@976|Bacteroidetes,47R0V@768503|Cytophagia	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CSH2_k127_4163983_0	1168034.FH5T_01600	1.425e-290	901.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,2FMNU@200643|Bacteroidia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_4163983_1	1341181.FLJC2902T_10630	1.07e-12	75.0	COG1657@1|root,COG1657@2|Bacteria,4P2T0@976|Bacteroidetes,1I7RX@117743|Flavobacteriia,2NTHE@237|Flavobacterium	976|Bacteroidetes	I	Squalene-hopene cyclase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
CSH2_k127_416726_1	1239962.C943_01555	3.99e-22	105.0	2DD3M@1|root,2ZGBQ@2|Bacteria,4P80Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_416726_0	755732.Fluta_1253	1.588e-196	617.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,2PADR@246874|Cryomorphaceae	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CSH2_k127_4173430_3	762903.Pedsa_1081	3.386e-23	108.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,1IPC8@117747|Sphingobacteriia	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CSH2_k127_4173430_0	649349.Lbys_2650	2.881e-98	328.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,47JJ8@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CSH2_k127_4173430_4	1408473.JHXO01000010_gene3578	3.937e-18	89.0	2E4AG@1|root,32Z66@2|Bacteria,4NUXA@976|Bacteroidetes,2FSMC@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG32209 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
CSH2_k127_4173430_2	1144343.PMI41_00748	3.78e-27	123.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2U95Q@28211|Alphaproteobacteria,43JWM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CSH2_k127_4173430_1	643867.Ftrac_2414	6.696e-49	193.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4173430_5	1356852.N008_03925	1.539e-16	90.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47RHW@768503|Cytophagia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_4181042_0	1168034.FH5T_12455	5.816e-45	173.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,2FMM9@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Cytoplasmic, score 8.96	gldB	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4181042_2	1041826.FCOL_03905	2.057e-32	128.0	2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,1I2XZ@117743|Flavobacteriia,2NWTR@237|Flavobacterium	976|Bacteroidetes	S	Gliding motility protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4181042_1	1279009.ADICEAN_01273	4.874e-39	148.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,47P6H@768503|Cytophagia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CSH2_k127_4182282_1	1408433.JHXV01000022_gene3148	8.636e-11	72.0	2FC5N@1|root,3449G@2|Bacteria,4P59J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4182282_0	374847.Kcr_0638	1.13e-19	104.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
CSH2_k127_4210134_0	1453500.AT05_06550	1.494e-266	828.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CSH2_k127_4212143_2	945713.IALB_2216	2.786e-08	55.0	2EIUI@1|root,33CJV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4212143_0	755732.Fluta_0180	2.39e-190	608.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia,2PAHS@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribonuclease E/G family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CSH2_k127_4212143_1	1286632.P278_10940	8.127e-152	488.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1HXZY@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CSH2_k127_4214946_2	1434325.AZQN01000001_gene528	1.626e-28	124.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,47PZ0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CSH2_k127_4214946_1	1296415.JACC01000059_gene1021	2.12e-52	199.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,1I3VW@117743|Flavobacteriia	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase,Esterase_phd
CSH2_k127_4214946_0	906888.JCM19314_3041	3.395e-131	426.0	COG1793@1|root,COG1793@2|Bacteria,4NEKP@976|Bacteroidetes,1HXWE@117743|Flavobacteriia,3HJMW@363408|Nonlabens	976|Bacteroidetes	L	DNA ligase N terminus	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
CSH2_k127_4228876_0	1279009.ADICEAN_01785	1.702e-222	709.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,47MF3@768503|Cytophagia	976|Bacteroidetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CSH2_k127_4248997_1	177437.HRM2_45380	2.216e-14	82.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MJKG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
CSH2_k127_4248997_0	641524.ADICYQ_5304	1.202e-126	417.0	2DB7P@1|root,2Z7MR@2|Bacteria,4NKTK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4251230_2	309807.SRU_1711	9.043e-17	86.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1FIZS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
CSH2_k127_4251230_1	509635.N824_11265	3.624e-21	100.0	COG4232@1|root,COG4232@2|Bacteria,4NQID@976|Bacteroidetes,1ISZ1@117747|Sphingobacteriia	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CSH2_k127_4251230_0	216432.CA2559_09878	2.969e-92	316.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CSH2_k127_4253289_1	932677.PAJ_2521	5.378e-18	96.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,1RZWJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
CSH2_k127_4253289_0	1123400.KB904765_gene1396	4.403e-49	186.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
CSH2_k127_4255163_0	929703.KE386491_gene2827	1.156e-103	342.0	COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47MUM@768503|Cytophagia	976|Bacteroidetes	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
CSH2_k127_4255163_2	1122176.KB903532_gene2630	6.019e-35	139.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1IYMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CSH2_k127_4255163_1	946077.W5A_06446	1.269e-40	157.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1I95J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4269213_4	1279017.AQYJ01000028_gene2050	8.954e-06	52.0	COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria,1SCQK@1236|Gammaproteobacteria,468R4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
CSH2_k127_4269213_0	1406840.Q763_03325	2.663e-271	851.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia,2NT3Q@237|Flavobacterium	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CSH2_k127_4269213_2	153721.MYP_2649	8.901e-22	98.0	COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,47VKT@768503|Cytophagia	976|Bacteroidetes	S	ATPase (AAA superfamily)	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
CSH2_k127_4269213_3	316274.Haur_3765	1.124e-15	82.0	COG2020@1|root,COG2020@2|Bacteria,2G9T5@200795|Chloroflexi,3761T@32061|Chloroflexia	32061|Chloroflexia	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CSH2_k127_4269213_1	743722.Sph21_1150	4.086e-109	357.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CSH2_k127_4280260_0	700598.Niako_3302	9.007e-70	256.0	COG1520@1|root,COG1520@2|Bacteria	700598.Niako_3302|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4287833_0	755732.Fluta_3835	5.138e-269	837.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia,2PAI4@246874|Cryomorphaceae	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CSH2_k127_4295055_1	1408433.JHXV01000038_gene2216	4.057e-31	125.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2PBI8@246874|Cryomorphaceae	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4295055_0	926562.Oweho_1031	1.879e-140	475.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
CSH2_k127_4295055_2	1279009.ADICEAN_02397	4.822e-21	102.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,47K4G@768503|Cytophagia	976|Bacteroidetes	M	COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CSH2_k127_4295848_0	1333507.AUTQ01000270_gene2969	1.114e-08	67.0	COG2356@1|root,COG2356@2|Bacteria,1R4W1@1224|Proteobacteria,1RPZG@1236|Gammaproteobacteria,2PZZG@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG2356 Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Endonuclease_1
CSH2_k127_4298204_2	929556.Solca_2299	2.826e-28	124.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CSH2_k127_4298204_0	485918.Cpin_7230	3.765e-112	372.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1IPRM@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CSH2_k127_4298204_1	762903.Pedsa_1986	2.065e-63	223.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQZ4@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_4308404_2	1453500.AT05_00835	2.811e-57	201.0	COG1145@1|root,COG1145@2|Bacteria,4NNF9@976|Bacteroidetes,1I1ZJ@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
CSH2_k127_4308404_0	865937.Gilli_0578	3.727e-89	306.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia,2P662@244698|Gillisia	976|Bacteroidetes	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
CSH2_k127_4308404_1	755732.Fluta_3159	6.748e-76	275.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia,2PAX7@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CSH2_k127_432708_1	588581.Cpap_3898	2.58e-49	183.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WN8Y@541000|Ruminococcaceae	186801|Clostridia	M	MBOAT family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CSH2_k127_432708_2	641524.ADICYQ_5832	5.065e-25	116.0	COG2755@1|root,COG2755@2|Bacteria,4NNAQ@976|Bacteroidetes,47TTV@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_432708_0	1185876.BN8_05499	3.556e-75	257.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CSH2_k127_432842_1	1453500.AT05_02795	7.377e-106	353.0	COG1629@1|root,COG4771@2|Bacteria,4PPAD@976|Bacteroidetes	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CSH2_k127_432842_0	755732.Fluta_3508	4.804e-163	519.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,2PAB9@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CSH2_k127_4330986_0	1346330.M472_13410	9.362e-157	500.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1IR3Y@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CSH2_k127_4330986_2	426117.M446_3014	5.777e-35	141.0	2E1E7@1|root,32WT9@2|Bacteria,1N6HI@1224|Proteobacteria,2UI2Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4330986_1	1454007.JAUG01000058_gene3505	1.638e-38	146.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1IP9F@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CSH2_k127_4360091_0	762903.Pedsa_0221	8.251e-88	302.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CSH2_k127_4360091_1	984262.SGRA_2354	7.075e-44	169.0	COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1IQUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
CSH2_k127_4364014_2	1408433.JHXV01000017_gene1628	5.094e-28	115.0	290ZX@1|root,2ZNMM@2|Bacteria,4P891@976|Bacteroidetes,1ICSI@117743|Flavobacteriia,2PC01@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4364014_0	1408433.JHXV01000017_gene1629	6.958e-311	984.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
CSH2_k127_4364014_1	385682.AFSL01000003_gene1912	2.814e-38	144.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
CSH2_k127_4375749_3	1408433.JHXV01000014_gene3628	1.437e-106	357.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_4375749_4	886379.AEWI01000026_gene451	7.212e-66	230.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,2FNEF@200643|Bacteroidia,3XJPC@558415|Marinilabiliaceae	976|Bacteroidetes	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CSH2_k127_4375749_1	216432.CA2559_00200	3.592e-207	667.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,1IJEU@117743|Flavobacteriia	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,MAM,UnbV_ASPIC,VCBS,fn3
CSH2_k127_4375749_2	755732.Fluta_1371	2.272e-120	400.0	COG2010@1|root,COG2010@2|Bacteria,4PMQB@976|Bacteroidetes,1IJZB@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4375749_0	755732.Fluta_1208	1.264e-307	972.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1HXMT@117743|Flavobacteriia,2PA9I@246874|Cryomorphaceae	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CSH2_k127_4378954_0	1185876.BN8_00768	1.127e-138	453.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,47MPX@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CSH2_k127_4378954_1	925409.KI911562_gene2282	3.825e-102	345.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
CSH2_k127_4378954_2	926549.KI421517_gene1121	4.297e-86	293.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CSH2_k127_4380992_1	338966.Ppro_2470	5.344e-54	197.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,42P7W@68525|delta/epsilon subdivisions,2WMHU@28221|Deltaproteobacteria,43SFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
CSH2_k127_4380992_0	385682.AFSL01000001_gene1997	5.922e-91	311.0	COG0438@1|root,COG0438@2|Bacteria,4NJ1W@976|Bacteroidetes,2FTR3@200643|Bacteroidia,3XK2C@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_4380992_2	435591.BDI_2206	4.176e-09	60.0	COG0438@1|root,COG0438@2|Bacteria,4NMHA@976|Bacteroidetes,2FTK8@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CSH2_k127_4386272_0	1237149.C900_04939	5.187e-160	516.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_4386272_1	1237149.C900_04940	1.707e-145	487.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47M2G@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_4388567_0	1279009.ADICEAN_03178	1.303e-46	174.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,47QB1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CSH2_k127_4399790_3	1168034.FH5T_04200	4.669e-52	184.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,2FNJ6@200643|Bacteroidia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CSH2_k127_4399790_1	1227276.HMPREF9148_01720	1.569e-74	253.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,2FRYX@200643|Bacteroidia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CSH2_k127_4399790_0	1380384.JADN01000006_gene2501	2.305e-98	325.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1HZJ6@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CSH2_k127_4399790_2	867902.Ornrh_1550	1.02e-57	206.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1HXJG@117743|Flavobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CSH2_k127_4399790_4	926549.KI421517_gene271	1.074e-49	181.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,47PSQ@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CSH2_k127_4416427_0	1034807.FBFL15_1190	4.552e-90	327.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NU73@237|Flavobacterium	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,Cleaved_Adhesin,MAM,P_proprotein,SBBP,fn3
CSH2_k127_4417892_0	1048983.EL17_13160	6.182e-105	348.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CSH2_k127_4417892_1	509635.N824_04010	2.068e-83	295.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IRAR@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
CSH2_k127_4426592_2	1121373.KB903638_gene925	2.092e-06	49.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,47JE4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CSH2_k127_4426592_3	1185876.BN8_06560	0.0002306	49.0	2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes,47SN3@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
CSH2_k127_4426592_0	926562.Oweho_1972	2.232e-70	250.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia,2PAN2@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
CSH2_k127_4426592_1	1454007.JAUG01000061_gene484	2.455e-50	186.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CSH2_k127_4447821_1	1408433.JHXV01000010_gene620	4.531e-14	80.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PA4T@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
CSH2_k127_4447821_0	547042.BACCOPRO_01879	3.077e-73	268.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,2FN9V@200643|Bacteroidia,4AM46@815|Bacteroidaceae	976|Bacteroidetes	M	protein involved in outer membrane biogenesis	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CSH2_k127_4455107_1	1250278.JQNQ01000001_gene1599	7.612e-24	105.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia	976|Bacteroidetes	S	amidohydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CSH2_k127_4455107_0	196367.JNFG01000058_gene567	4.284e-146	473.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VJD8@28216|Betaproteobacteria,1K2R6@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Aminotransferase	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_4458721_0	929556.Solca_2664	2.546e-168	569.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
CSH2_k127_4460140_4	1123037.AUDE01000012_gene106	2.339e-31	142.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4460140_3	1122176.KB903587_gene4512	2.258e-44	183.0	COG3209@1|root,COG3291@1|root,COG4935@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
CSH2_k127_4460140_5	1408433.JHXV01000009_gene1250	1.786e-16	94.0	COG4935@1|root,COG4935@2|Bacteria,4PP7N@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4460140_2	880526.KE386488_gene667	3.99e-51	185.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,2FNMW@200643|Bacteroidia,22UH7@171550|Rikenellaceae	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CSH2_k127_4460140_1	1492922.GY26_01150	1.169e-51	193.0	COG2503@1|root,COG2503@2|Bacteria,1RB4N@1224|Proteobacteria,1RY2I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acid phosphatase	hel	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
CSH2_k127_4460140_0	946077.W5A_02760	1.92e-88	299.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CSH2_k127_4469406_2	755732.Fluta_2846	3.233e-47	177.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1I8AX@117743|Flavobacteriia,2PAB3@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CSH2_k127_4469406_0	1122176.KB903535_gene1970	2.388e-81	292.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
CSH2_k127_4469406_1	694427.Palpr_2188	1.008e-56	201.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,22X9V@171551|Porphyromonadaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CSH2_k127_4474138_1	700598.Niako_3946	2e-46	170.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CSH2_k127_4474138_0	216432.CA2559_08386	1.658e-119	397.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1HWM5@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CSH2_k127_4474138_2	1469557.JSWF01000024_gene1785	2.698e-45	172.0	COG0500@1|root,COG2226@2|Bacteria,4PPSE@976|Bacteroidetes,1I5IJ@117743|Flavobacteriia	976|Bacteroidetes	Q	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CSH2_k127_4478335_0	1121896.JMLU01000003_gene2211	8.454e-116	377.0	COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1IFBS@117743|Flavobacteriia,2NVEG@237|Flavobacterium	976|Bacteroidetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
CSH2_k127_4478335_1	1123400.KB904765_gene1396	3.678e-47	179.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
CSH2_k127_4486841_0	760192.Halhy_6848	4.537e-119	407.0	COG4932@1|root,COG4932@2|Bacteria,4NKIK@976|Bacteroidetes	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4504597_3	1220534.B655_2107	5.091e-74	273.0	COG0642@1|root,arCOG02348@1|root,arCOG02348@2157|Archaea,arCOG06192@2157|Archaea	2157|Archaea	T	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CSH2_k127_4504597_2	1408433.JHXV01000015_gene1712	2.004e-116	379.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia,2PAUQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CSH2_k127_4504597_0	1211813.CAPH01000013_gene486	2.255e-207	670.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,2FMM6@200643|Bacteroidia,22U46@171550|Rikenellaceae	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
CSH2_k127_4504597_1	1408433.JHXV01000006_gene2780	1.263e-127	416.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia,2PA7D@246874|Cryomorphaceae	976|Bacteroidetes	EF	Phosphoribosyl synthetase-associated domain	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CSH2_k127_4504597_5	869213.JCM21142_52189	5.54e-42	163.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,47NVP@768503|Cytophagia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CSH2_k127_4504597_4	742725.HMPREF9450_01042	7.623e-69	239.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,2FN36@200643|Bacteroidia,22UDM@171550|Rikenellaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CSH2_k127_4504597_6	1267211.KI669560_gene2147	3.256e-18	91.0	COG1506@1|root,COG1506@2|Bacteria,4NGW1@976|Bacteroidetes,1J11I@117747|Sphingobacteriia	976|Bacteroidetes	E	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
CSH2_k127_4508074_0	762903.Pedsa_2638	3.741e-31	139.0	COG2730@1|root,COG2730@2|Bacteria,4NH83@976|Bacteroidetes,1IRWN@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
CSH2_k127_4510099_0	1121904.ARBP01000001_gene5769	0.0	1233.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CSH2_k127_4529437_3	1408473.JHXO01000011_gene3147	5.588e-28	116.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,2FNI4@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CSH2_k127_4529437_2	649349.Lbys_0602	2.875e-88	302.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,47J93@768503|Cytophagia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CSH2_k127_4529437_0	755732.Fluta_4067	5.043e-209	659.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2PBCM@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CSH2_k127_4529437_1	1121481.AUAS01000006_gene877	1.131e-166	556.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
CSH2_k127_4529446_4	666685.R2APBS1_0128	0.0001203	51.0	COG0526@1|root,COG0526@2|Bacteria,1RAW3@1224|Proteobacteria,1S43V@1236|Gammaproteobacteria,1XCBM@135614|Xanthomonadales	135614|Xanthomonadales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	LGT,Redoxin
CSH2_k127_4529446_2	1122605.KB893638_gene3434	3.91e-30	128.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1ITRK@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CSH2_k127_4529446_0	755732.Fluta_2667	3.107e-85	288.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia,2PANI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
CSH2_k127_4529446_3	1408433.JHXV01000002_gene316	1.465e-27	117.0	COG3427@1|root,COG3427@2|Bacteria,4PHJK@976|Bacteroidetes,1IGIK@117743|Flavobacteriia,2PB7C@246874|Cryomorphaceae	976|Bacteroidetes	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4529446_1	1123035.ARLA01000028_gene2071	2.822e-33	135.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,4C2WF@83612|Psychroflexus	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CSH2_k127_4535058_0	265072.Mfla_2280	1.015e-150	487.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,2KKH8@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CSH2_k127_4535058_1	1121104.AQXH01000001_gene1193	1.716e-66	229.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CSH2_k127_4544032_0	938709.AUSH02000051_gene200	3.653e-39	167.0	COG1404@1|root,COG3291@1|root,COG3405@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SLH,SdrD_B
CSH2_k127_4547805_0	755732.Fluta_0535	2.2e-132	440.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1I7MT@117743|Flavobacteriia,2PAFS@246874|Cryomorphaceae	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CSH2_k127_4562864_0	755732.Fluta_1807	4.032e-236	739.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1HXHB@117743|Flavobacteriia,2PA5B@246874|Cryomorphaceae	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
CSH2_k127_4565011_0	272559.BF9343_3401	3.825e-20	90.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,2FMIQ@200643|Bacteroidia,4ANA6@815|Bacteroidaceae	976|Bacteroidetes	M	Peptidase, M23 family	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CSH2_k127_4565239_0	1392490.JHZX01000001_gene869	6.305e-148	489.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_4577283_0	743722.Sph21_3880	9.226e-90	300.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CSH2_k127_4577283_1	760192.Halhy_4170	8.942e-37	155.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1IQZP@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,fn3_3
CSH2_k127_4586869_1	649349.Lbys_2286	1.188e-67	237.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,47MWN@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CSH2_k127_4586869_2	1229276.DI53_1559	2.299e-42	166.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes,1J13D@117747|Sphingobacteriia	976|Bacteroidetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CSH2_k127_4586869_0	1286632.P278_02820	1.236e-255	804.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CSH2_k127_4586869_4	869213.JCM21142_275	5.48e-34	136.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CSH2_k127_4586869_3	755732.Fluta_2665	9.58e-35	144.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,1HZU1@117743|Flavobacteriia,2PB6X@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
CSH2_k127_4586869_5	452471.Aasi_1719	3.651e-16	78.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,47RUZ@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CSH2_k127_4591461_1	1408433.JHXV01000010_gene505	9.177e-19	96.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,1IC47@117743|Flavobacteriia,2PB8G@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
CSH2_k127_4591461_0	1166018.FAES_1219	2.504e-86	297.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,47JVC@768503|Cytophagia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CSH2_k127_460166_0	1356852.N008_08405	3.043e-71	245.0	COG0500@1|root,COG0500@2|Bacteria,4PP98@976|Bacteroidetes,47PJZ@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
CSH2_k127_460166_1	1168289.AJKI01000002_gene2725	1.387e-28	120.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,2FT27@200643|Bacteroidia,3XK75@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosome-binding factor A	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CSH2_k127_460166_2	926559.JoomaDRAFT_0158	8.817e-10	66.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia	976|Bacteroidetes	V	abc transporter (atp-binding protein)	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CSH2_k127_4610790_1	984262.SGRA_2624	2.017e-20	96.0	COG1572@1|root,COG3209@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CSH2_k127_4610790_0	1408473.JHXO01000013_gene523	9.407e-186	589.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,2FNXA@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_4610790_2	1121896.JMLU01000011_gene1504	7.99e-18	91.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1HYEQ@117743|Flavobacteriia,2NTIN@237|Flavobacterium	976|Bacteroidetes	S	(Lipo)protein	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CSH2_k127_4615861_1	1313301.AUGC01000003_gene2137	1.762e-09	58.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes	976|Bacteroidetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CSH2_k127_4615861_0	1358423.N180_12245	9.382e-144	467.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CSH2_k127_4615861_2	1223410.KN050846_gene812	0.0001569	48.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4620664_1	1408433.JHXV01000015_gene1745	7.166e-67	239.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C,DUF4150,PorP_SprF
CSH2_k127_4620664_0	1408433.JHXV01000015_gene1746	2.005e-110	385.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
CSH2_k127_4626414_3	880071.Fleli_3085	1.107e-63	227.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47RHW@768503|Cytophagia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_4626414_2	1122605.KB893625_gene2310	2.457e-67	237.0	COG2755@1|root,COG2755@2|Bacteria,4NHWJ@976|Bacteroidetes,1IS35@117747|Sphingobacteriia	976|Bacteroidetes	E	Lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CSH2_k127_4626414_1	1166018.FAES_3690	3.478e-104	352.0	COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,47M83@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CSH2_k127_4626414_4	1168034.FH5T_13015	1.705e-50	186.0	COG0778@1|root,COG0778@2|Bacteria,4NKRC@976|Bacteroidetes,2FZX8@200643|Bacteroidia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CSH2_k127_4626414_0	1131812.JQMS01000001_gene1692	3.07e-113	370.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,2NSN5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CSH2_k127_4644143_1	755732.Fluta_0691	2.043e-26	114.0	2A21C@1|root,30QBC@2|Bacteria,4PGY1@976|Bacteroidetes,1IFSM@117743|Flavobacteriia,2PBPD@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4644143_2	1123248.KB893322_gene598	5.016e-21	100.0	COG2318@1|root,COG2318@2|Bacteria,4NPSF@976|Bacteroidetes	976|Bacteroidetes	S	Pfam DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CSH2_k127_4644143_0	1122605.KB893627_gene3013	1.043e-113	371.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1IPIU@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
CSH2_k127_4649254_1	1237149.C900_02938	2.253e-25	120.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_4,Big_5,DUF3494,LTD,SLH
CSH2_k127_4649254_0	1121288.AULL01000016_gene661	3.7e-94	330.0	COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes,1I8IS@117743|Flavobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_4668862_0	1279009.ADICEAN_00977	0.0	1017.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CSH2_k127_467128_0	1122605.KB893628_gene4483	9.728e-125	414.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,1IPR3@117747|Sphingobacteriia	976|Bacteroidetes	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CSH2_k127_467128_1	485918.Cpin_0179	4.341e-09	57.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CSH2_k127_4692521_3	760192.Halhy_2897	1.2e-34	136.0	COG1216@1|root,COG1216@2|Bacteria,4NGHQ@976|Bacteroidetes,1IS78@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
CSH2_k127_4692521_0	867903.ThesuDRAFT_01782	1.491e-139	451.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,24KZ9@186801|Clostridia,3WDN6@538999|Clostridiales incertae sedis	186801|Clostridia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CSH2_k127_4692521_2	1237149.C900_03830	8.931e-63	231.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47T9B@768503|Cytophagia	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CSH2_k127_4692521_1	700598.Niako_1886	4.769e-78	265.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1IQ62@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CSH2_k127_4695714_1	468059.AUHA01000008_gene2750	1.151e-38	147.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CSH2_k127_4695714_0	1279009.ADICEAN_03476	1.044e-156	512.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47JW1@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CSH2_k127_4704923_0	760192.Halhy_3824	4.634e-167	542.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CSH2_k127_4711339_0	1237149.C900_00336	4.709e-104	352.0	COG2244@1|root,COG2244@2|Bacteria,4NI21@976|Bacteroidetes,47QZ9@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CSH2_k127_4711339_1	1237149.C900_00337	2.471e-35	149.0	28MJC@1|root,2ZAVX@2|Bacteria,4NP81@976|Bacteroidetes,47Q3J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4719627_2	1089547.KB913013_gene4561	1.097e-23	117.0	COG1404@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NPFV@976|Bacteroidetes	976|Bacteroidetes	MO	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4719627_0	1341181.FLJC2902T_15110	5.767e-39	165.0	COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CSH2_k127_4719627_1	1313421.JHBV01000039_gene2675	2.869e-24	108.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes	976|Bacteroidetes	E	peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CSH2_k127_4720755_0	1107311.Q767_12420	1.245e-240	766.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
CSH2_k127_4730669_0	1121094.KB894659_gene2639	2.685e-124	413.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,2FM6G@200643|Bacteroidia,4AKWN@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_4730669_1	1227739.Hsw_1175	3.763e-52	191.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CSH2_k127_4731178_1	1223410.KN050846_gene1382	2.96e-30	131.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria,4NN21@976|Bacteroidetes,1I1UJ@117743|Flavobacteriia	976|Bacteroidetes	UW	arginyl-trna synthetase	-	-	-	-	-	-	-	-	-	-	-	-	PA14
CSH2_k127_4731178_0	391598.FBBAL38_01450	1.642e-190	608.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia	976|Bacteroidetes	C	FAD linked	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CSH2_k127_4731178_2	1242864.D187_001350	9.759e-09	62.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN,MORN_2
CSH2_k127_4735564_0	945713.IALB_3159	7.621e-50	197.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	AAA_15
CSH2_k127_4747571_2	926559.JoomaDRAFT_2264	1.751e-21	97.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CSH2_k127_4747571_0	1408433.JHXV01000010_gene542	1.28e-71	256.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia,2PAXM@246874|Cryomorphaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_4747571_1	1121373.KB903643_gene3550	2.467e-35	146.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,47PD6@768503|Cytophagia	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CSH2_k127_4752151_0	641524.ADICYQ_4904	3.81e-146	474.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KQS@768503|Cytophagia	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CSH2_k127_4752151_2	1279009.ADICEAN_04037	3.324e-116	388.0	COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
CSH2_k127_4752151_1	1122176.KB903546_gene1027	1.723e-124	433.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,MAM,UnbV_ASPIC,VCBS,fn3
CSH2_k127_4752151_3	1122621.ATZA01000024_gene2153	2.475e-27	118.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1IPBH@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CSH2_k127_475402_3	1461577.CCMH01000003_gene1036	1.368e-08	58.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CSH2_k127_475402_0	762903.Pedsa_1960	1.169e-92	324.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,1INU7@117747|Sphingobacteriia	976|Bacteroidetes	I	Alpha beta hydrolase	pcbD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CSH2_k127_475402_2	1121895.Q765_10910	7.295e-35	138.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia,2NTX5@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CSH2_k127_475402_1	742725.HMPREF9450_01336	1.681e-64	227.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,22U6D@171550|Rikenellaceae	976|Bacteroidetes	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CSH2_k127_4763636_2	869213.JCM21142_104191	5.932e-28	118.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,47KDM@768503|Cytophagia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_4763636_1	1004149.AFOE01000050_gene2647	1.012e-68	244.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CSH2_k127_4763636_0	984262.SGRA_1047	2.022e-108	363.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CSH2_k127_4763636_3	1207058.L53_06755	0.0004082	44.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,43WRX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Glycine cleavage system T protein	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CSH2_k127_479897_0	1195246.AGRI_05407	5.661e-185	588.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,1S1TG@1236|Gammaproteobacteria,4657D@72275|Alteromonadaceae	1236|Gammaproteobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CSH2_k127_479897_1	1305737.JAFX01000001_gene1582	1.054e-59	216.0	2DBB9@1|root,2Z86U@2|Bacteria,4NI91@976|Bacteroidetes,47JBX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4802318_0	1223410.KN050846_gene331	3.864e-42	162.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
CSH2_k127_4802318_1	700598.Niako_5698	5.646e-30	127.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,1ITSA@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CSH2_k127_4830672_1	714943.Mucpa_4339	8.566e-11	67.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IT0W@117747|Sphingobacteriia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
CSH2_k127_4830672_0	468059.AUHA01000004_gene2080	5.205e-101	339.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose reductase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CSH2_k127_483621_1	378806.STAUR_6902	7.168e-54	195.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,43C34@68525|delta/epsilon subdivisions,2WQEN@28221|Deltaproteobacteria,2YVEG@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CSH2_k127_483621_3	1517682.HW49_07425	2.132e-08	58.0	29982@1|root,2ZWBD@2|Bacteria,4P96H@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_483621_0	992406.RIA_1920	7.848e-146	479.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,1HY2R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CSH2_k127_483621_2	1122222.AXWR01000052_gene66	2.536e-13	78.0	2ENQZ@1|root,33GC6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4855433_1	926562.Oweho_1440	7.696e-19	93.0	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,1HZ14@117743|Flavobacteriia,2PAXQ@246874|Cryomorphaceae	976|Bacteroidetes	L	COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
CSH2_k127_4855433_0	177437.HRM2_45380	5.026e-28	125.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MJKG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
CSH2_k127_4864993_1	1121890.AUDO01000003_gene1814	3.063e-60	215.0	2AEQA@1|root,314KU@2|Bacteria,4PJ85@976|Bacteroidetes,1ICT3@117743|Flavobacteriia,2NUK1@237|Flavobacterium	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
CSH2_k127_4864993_2	755732.Fluta_2145	4.459e-16	80.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CSH2_k127_4864993_0	1122179.KB890436_gene1370	8.124e-68	243.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
CSH2_k127_4866760_1	1123277.KB893244_gene5107	3.347e-07	63.0	COG3179@1|root,COG3179@2|Bacteria,4NF8K@976|Bacteroidetes,47QM0@768503|Cytophagia	976|Bacteroidetes	S	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CSH2_k127_4866760_0	1237149.C900_05263	6.646e-19	98.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4867276_0	1227739.Hsw_4111	1.429e-37	160.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
CSH2_k127_4874956_1	754027.HMPREF9554_02639	4.025e-09	60.0	COG4953@1|root,COG4953@2|Bacteria,2J606@203691|Spirochaetes	203691|Spirochaetes	M	Penicillin-binding Protein	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CSH2_k127_48759_1	1408433.JHXV01000026_gene3066	1.679e-46	175.0	COG5587@1|root,COG5587@2|Bacteria,4NRNM@976|Bacteroidetes,1I8TV@117743|Flavobacteriia,2PATJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
CSH2_k127_48759_3	1122226.AUHX01000006_gene2070	3.242e-35	144.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CSH2_k127_48759_2	742766.HMPREF9455_02684	1.396e-45	168.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,2FT44@200643|Bacteroidia,22Y4C@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
CSH2_k127_48759_0	1279009.ADICEAN_00402	2.828e-153	504.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,47NEG@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CSH2_k127_488047_2	945713.IALB_0720	1.482e-56	205.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CSH2_k127_488047_0	1121889.AUDM01000011_gene2735	4.089e-130	426.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia,2NTIR@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CSH2_k127_488047_1	1122621.ATZA01000051_gene2836	2.129e-60	217.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,1IR1P@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	nhaS3	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CSH2_k127_4902662_0	1122176.KB903565_gene3200	7.132e-110	375.0	COG0308@1|root,COG0308@2|Bacteria,4P1D6@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_4904712_0	313596.RB2501_04560	3.211e-175	560.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CSH2_k127_4916843_4	56107.Cylst_3960	9.583e-09	61.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HR5M@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CSH2_k127_4916843_3	497964.CfE428DRAFT_0862	4.904e-28	123.0	COG2091@1|root,COG2091@2|Bacteria,46T3D@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CSH2_k127_4916843_0	585543.HMPREF0969_01030	7.749e-119	398.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,2FNT1@200643|Bacteroidia,4AKAI@815|Bacteroidaceae	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
CSH2_k127_4916843_5	1121129.KB903374_gene553	8.007e-05	55.0	2DNC5@1|root,32WQD@2|Bacteria,4PFGM@976|Bacteroidetes,2G1FW@200643|Bacteroidia,22Z16@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
CSH2_k127_4916843_1	1127696.HMPREF9134_00769	1.308e-46	185.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,2FSR0@200643|Bacteroidia,22XZ4@171551|Porphyromonadaceae	976|Bacteroidetes	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CSH2_k127_4916843_2	1122179.KB890497_gene2856	5.836e-45	173.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1ISUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CSH2_k127_4917420_1	1250006.JHZZ01000001_gene238	1.034e-53	207.0	COG2133@1|root,COG3568@1|root,COG5492@1|root,COG2133@2|Bacteria,COG3568@2|Bacteria,COG5492@2|Bacteria,4NPDY@976|Bacteroidetes,1I1DH@117743|Flavobacteriia,3VXGV@52959|Polaribacter	976|Bacteroidetes	GN	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4917420_0	1408433.JHXV01000002_gene476	4.869e-94	316.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1IJGW@117743|Flavobacteriia,2PAZ2@246874|Cryomorphaceae	976|Bacteroidetes	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
CSH2_k127_4930772_1	1408433.JHXV01000001_gene703	1.54e-47	176.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PC5X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
CSH2_k127_4930772_0	153721.MYP_1295	1.222e-69	256.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47NKW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_4941317_1	1122223.KB890697_gene1121	3.11e-96	330.0	COG0438@1|root,COG0438@2|Bacteria,1WIJ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_4941317_2	616991.JPOO01000003_gene2529	7.788e-11	74.0	COG3307@1|root,COG3307@2|Bacteria,4PIFQ@976|Bacteroidetes,1IF9H@117743|Flavobacteriia,23HQE@178469|Arenibacter	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CSH2_k127_4941317_0	1122621.ATZA01000002_gene1617	3.201e-127	413.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1IPAD@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CSH2_k127_4953156_0	1121127.JAFA01000031_gene4654	2.973e-153	497.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2VJ40@28216|Betaproteobacteria,1K4VW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CSH2_k127_4953156_1	335543.Sfum_1774	1.352e-32	130.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria,2MR5U@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
CSH2_k127_497232_0	385682.AFSL01000047_gene524	1.336e-56	215.0	COG0438@1|root,COG0438@2|Bacteria,4NPDT@976|Bacteroidetes,2FSPY@200643|Bacteroidia	976|Bacteroidetes	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CSH2_k127_497232_1	1033802.SSPSH_000285	3.215e-46	186.0	COG1216@1|root,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,1S5S5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_497232_2	1121373.KB903632_gene537	1.387e-17	92.0	COG1215@1|root,COG1215@2|Bacteria,4PME9@976|Bacteroidetes,47Y2R@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_497301_3	1268237.G114_18481	0.0002405	44.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,1RRBX@1236|Gammaproteobacteria,1Y4R2@135624|Aeromonadales	135624|Aeromonadales	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
CSH2_k127_497301_1	1349822.NSB1T_13055	1.768e-132	442.0	COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,2FMSK@200643|Bacteroidia,22W02@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
CSH2_k127_497301_0	1121129.KB903360_gene3345	1.137e-150	479.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,2FMME@200643|Bacteroidia,22VYD@171551|Porphyromonadaceae	976|Bacteroidetes	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CSH2_k127_497301_2	1288963.ADIS_0868	2.488e-55	199.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,47JDA@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CSH2_k127_498132_0	984262.SGRA_2430	1.224e-226	726.0	COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,1IQ0D@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CSH2_k127_5007435_1	1408433.JHXV01000032_gene1131	9.18e-17	85.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CSH2_k127_5007435_0	1166018.FAES_5174	1.079e-32	134.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,47QJ2@768503|Cytophagia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CSH2_k127_5016841_2	865937.Gilli_3074	1.911e-23	102.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1I1XH@117743|Flavobacteriia,2P6N8@244698|Gillisia	976|Bacteroidetes	H	Dephospho-CoA kinase	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CSH2_k127_5016841_1	1270196.JCKI01000008_gene1677	9.893e-25	107.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1IZTG@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CSH2_k127_5016841_3	1469557.JSWF01000014_gene2638	4.658e-23	104.0	2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,1IJMJ@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CSH2_k127_5016841_0	1408433.JHXV01000021_gene1679	3.713e-48	179.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia,2PAR4@246874|Cryomorphaceae	976|Bacteroidetes	K	NusB family	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CSH2_k127_5023646_0	760192.Halhy_2129	1.766e-145	470.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
CSH2_k127_5023646_1	929556.Solca_0931	1.521e-68	244.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
CSH2_k127_5047176_0	755732.Fluta_2447	1.264e-195	615.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWRC@117743|Flavobacteriia,2PAEC@246874|Cryomorphaceae	976|Bacteroidetes	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CSH2_k127_5047176_2	485918.Cpin_6208	2.345e-06	56.0	COG1514@1|root,COG1514@2|Bacteria,4NZN5@976|Bacteroidetes,1IZG4@117747|Sphingobacteriia	976|Bacteroidetes	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CSH2_k127_5047176_1	391596.PBAL39_04234	3.155e-162	517.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CSH2_k127_5054485_1	1408473.JHXO01000016_gene1933	3.124e-29	126.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,2FT12@200643|Bacteroidia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CSH2_k127_5054485_0	869213.JCM21142_403	4.048e-110	364.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47TXK@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CSH2_k127_5054485_2	861299.J421_1316	1.306e-11	68.0	COG4430@1|root,COG4430@2|Bacteria,1ZUYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
CSH2_k127_507507_0	1082931.KKY_3001	1.293e-36	148.0	COG1413@1|root,COG1413@2|Bacteria,1MZV0@1224|Proteobacteria,2UERM@28211|Alphaproteobacteria,3N8R0@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_507507_2	631454.N177_3358	2.253e-15	89.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2TTEI@28211|Alphaproteobacteria,1JNXZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CSH2_k127_507507_1	880071.Fleli_3085	7.302e-29	123.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47RHW@768503|Cytophagia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CSH2_k127_5075558_1	1408433.JHXV01000002_gene334	1.429e-57	218.0	COG2374@1|root,COG4935@1|root,COG2374@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,LTD,SLH
CSH2_k127_5075558_0	926549.KI421517_gene2869	3.951e-172	546.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47JMW@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CSH2_k127_5095208_2	1121373.KB903620_gene2025	4.841e-36	140.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CSH2_k127_5095208_0	929556.Solca_4341	5.148e-101	351.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IR0N@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CSH2_k127_5095208_1	929556.Solca_4343	2.485e-73	265.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CSH2_k127_5107384_0	1453500.AT05_07745	3.506e-261	810.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CSH2_k127_5107384_2	1122621.ATZA01000025_gene2415	5.392e-15	77.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1ITVV@117747|Sphingobacteriia	976|Bacteroidetes	C	ATP synthase	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CSH2_k127_5107384_1	1408433.JHXV01000001_gene721	4.894e-25	111.0	COG0457@1|root,COG0457@2|Bacteria,4PJHB@976|Bacteroidetes,1IMQ8@117743|Flavobacteriia,2PB7I@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CSH2_k127_5111493_2	1122176.KB903609_gene5257	2.57e-14	79.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1IQ05@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CSH2_k127_5111493_0	45351.EDO26796	1.383e-83	290.0	COG0010@1|root,KOG2965@2759|Eukaryota,38CCH@33154|Opisthokonta,3BCCT@33208|Metazoa	33208|Metazoa	E	arginase activity	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CSH2_k127_5111493_1	755732.Fluta_1778	3.919e-52	201.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI0B@976|Bacteroidetes,1IG7A@117743|Flavobacteriia,2PBJ3@246874|Cryomorphaceae	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_5122146_0	926562.Oweho_1440	2.096e-121	398.0	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,1HZ14@117743|Flavobacteriia,2PAXQ@246874|Cryomorphaceae	976|Bacteroidetes	L	COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
CSH2_k127_5122146_2	761193.Runsl_5624	6.782e-27	114.0	2CCSR@1|root,32RSC@2|Bacteria,4NT8X@976|Bacteroidetes,47W4Z@768503|Cytophagia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CSH2_k127_5122146_1	929703.KE386491_gene510	2.26e-27	117.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,47R3Q@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM bacillithiol system protein YtxJ	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
CSH2_k127_5122146_3	1120951.AUBG01000002_gene1204	4.717e-15	78.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,1HWW1@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CSH2_k127_5143157_0	926562.Oweho_2422	8.738e-110	367.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
CSH2_k127_5143157_1	755732.Fluta_0380	5.306e-36	154.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CSH2_k127_5148955_0	755732.Fluta_2261	4.433e-48	181.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1HYRJ@117743|Flavobacteriia,2PB10@246874|Cryomorphaceae	976|Bacteroidetes	P	ZIP Zinc transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
CSH2_k127_5148955_1	1227739.Hsw_0027	1.601e-44	173.0	COG2227@1|root,COG2227@2|Bacteria,4PKUR@976|Bacteroidetes,47XZB@768503|Cytophagia	976|Bacteroidetes	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
CSH2_k127_5148955_2	385682.AFSL01000003_gene1912	2.592e-43	160.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
CSH2_k127_5154429_1	1168289.AJKI01000012_gene316	1.323e-13	76.0	COG0297@1|root,COG0297@2|Bacteria,4PP8M@976|Bacteroidetes,2G144@200643|Bacteroidia,3XJT9@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_5154429_0	329726.AM1_3609	7.307e-101	338.0	COG1087@1|root,COG1087@2|Bacteria,1GDSP@1117|Cyanobacteria	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CSH2_k127_5154429_2	886379.AEWI01000052_gene2670	1.249e-08	59.0	COG0438@1|root,COG0438@2|Bacteria,4NZMT@976|Bacteroidetes,2G1JS@200643|Bacteroidia,3XKI2@558415|Marinilabiliaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
CSH2_k127_5167677_0	1166018.FAES_4244	1.582e-105	358.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,47NWS@768503|Cytophagia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
CSH2_k127_5171091_0	743722.Sph21_5193	2.271e-73	259.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CSH2_k127_5171091_1	1121898.Q766_12595	7.456e-25	112.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1I2BT@117743|Flavobacteriia,2NVWV@237|Flavobacterium	976|Bacteroidetes	Q	thioesterase	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
CSH2_k127_5179730_1	1122176.KB903531_gene2905	4.435e-32	136.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CSH2_k127_5179730_0	1168034.FH5T_21120	7.97e-54	197.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,2FKZG@200643|Bacteroidia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CSH2_k127_5179730_2	760192.Halhy_0269	5.947e-19	91.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1IQFD@117747|Sphingobacteriia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CSH2_k127_5179735_0	1227739.Hsw_0324	1.906e-104	357.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,47JKP@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
CSH2_k127_518694_1	1317118.ATO8_15553	6.775e-06	59.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2V8XR@28211|Alphaproteobacteria,4KNPG@93682|Roseivivax	28211|Alphaproteobacteria	Q	von Willebrand factor (vWF) type D domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,NIDO,VWD
CSH2_k127_518694_0	1392490.JHZX01000001_gene869	1.327e-55	214.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_5205370_2	1454004.AW11_00278	1.733e-15	89.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VZID@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
CSH2_k127_5205370_0	1123248.KB893348_gene193	2.594e-35	146.0	COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CSH2_k127_5205370_1	755732.Fluta_3599	2.006e-26	117.0	COG4188@1|root,COG4188@2|Bacteria,4P2MC@976|Bacteroidetes,1I8M4@117743|Flavobacteriia	976|Bacteroidetes	S	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase
CSH2_k127_5207703_1	1408433.JHXV01000014_gene3691	9.282e-38	154.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CSH2_k127_5207703_0	1380384.JADN01000004_gene2038	6.768e-202	635.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CSH2_k127_5211668_0	1121899.Q764_02600	2.677e-92	314.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia,2NSMP@237|Flavobacterium	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CSH2_k127_5211668_1	1346330.M472_02235	2.093e-73	255.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1INZ4@117747|Sphingobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CSH2_k127_5211668_2	1408473.JHXO01000006_gene1149	1.372e-41	155.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
CSH2_k127_5215841_0	742725.HMPREF9450_00490	0.0	1084.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,2FMCP@200643|Bacteroidia,22U0Q@171550|Rikenellaceae	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CSH2_k127_5219145_1	582515.KR51_00000010	2.211e-21	110.0	COG1572@1|root,COG2304@1|root,COG2931@1|root,COG3210@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
CSH2_k127_5219145_0	1166018.FAES_2889	1.94e-46	190.0	COG1361@1|root,COG2133@1|root,COG3291@1|root,COG1361@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,47QVQ@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
CSH2_k127_5226626_0	1049564.TevJSym_ac01880	1.205e-27	131.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	nucH	-	3.1.3.5	ko:K01081,ko:K07004	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Exo_endo_phos,LTD,Metallophos
CSH2_k127_5226626_1	1122179.KB890413_gene4703	2.878e-09	71.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
CSH2_k127_5226872_0	313596.RB2501_16164	7.885e-83	285.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1HX1G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CSH2_k127_5226872_1	1267211.KI669560_gene521	1.817e-76	261.0	COG3000@1|root,COG3000@2|Bacteria,4NMKR@976|Bacteroidetes,1ISPG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_5227729_1	1121287.AUMU01000003_gene2927	0.0006758	51.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NJHV@976|Bacteroidetes,1IKPD@117743|Flavobacteriia,3ZUS4@59732|Chryseobacterium	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CSH2_k127_5232394_1	1408433.JHXV01000024_gene1479	3.186e-48	181.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,1HZ71@117743|Flavobacteriia,2PBGE@246874|Cryomorphaceae	976|Bacteroidetes	T	GHKL domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CSH2_k127_5232394_2	1122176.KB903554_gene3957	1.324e-23	117.0	COG1404@1|root,COG3209@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,4PM4C@976|Bacteroidetes	976|Bacteroidetes	O	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_5232394_0	760192.Halhy_6848	1.334e-79	288.0	COG4932@1|root,COG4932@2|Bacteria,4NKIK@976|Bacteroidetes	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5233333_0	1408433.JHXV01000017_gene1592	1.49e-247	769.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia,2PAI4@246874|Cryomorphaceae	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CSH2_k127_5233333_1	755732.Fluta_3835	9.201e-16	78.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,1HWPA@117743|Flavobacteriia,2PAI4@246874|Cryomorphaceae	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CSH2_k127_523380_0	1453498.LG45_13070	1.045e-55	199.0	28IZ7@1|root,2Z8WQ@2|Bacteria,4NIAK@976|Bacteroidetes,1I09F@117743|Flavobacteriia,2NTW2@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_523380_1	700598.Niako_2785	1.051e-18	95.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CSH2_k127_523380_2	1313421.JHBV01000034_gene1686	0.0004689	51.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,SprB
CSH2_k127_5252367_1	1269813.ATUL01000040_gene1380	6.036e-06	55.0	COG2244@1|root,COG2244@2|Bacteria,1RC2S@1224|Proteobacteria,1S5QR@1236|Gammaproteobacteria,1X0JY@135613|Chromatiales	135613|Chromatiales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
CSH2_k127_5252367_0	1313301.AUGC01000013_gene1273	3.298e-50	195.0	COG0438@1|root,COG0438@2|Bacteria,4NK6N@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CSH2_k127_5263132_1	1122605.KB893631_gene3909	1.358e-75	264.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1IQF5@117747|Sphingobacteriia	976|Bacteroidetes	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CSH2_k127_5263132_0	1123276.KB893246_gene541	8.252e-146	474.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,47JNS@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CSH2_k127_5263132_2	706436.HMPREF9074_08780	2.436e-50	182.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia,1ES0J@1016|Capnocytophaga	976|Bacteroidetes	S	Fe-S metabolism associated domain protein	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
CSH2_k127_5263132_3	997352.HMPREF9419_1304	9.28e-10	64.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,2FT2N@200643|Bacteroidia	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CSH2_k127_5267221_0	1408473.JHXO01000004_gene83	2.874e-219	704.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,2G3GJ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
CSH2_k127_5267221_2	706436.HMPREF9074_08804	1.802e-05	53.0	COG2849@1|root,COG2849@2|Bacteria,4NQZT@976|Bacteroidetes,1I3HG@117743|Flavobacteriia,1EQ2Z@1016|Capnocytophaga	976|Bacteroidetes	S	MORN repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CSH2_k127_5267221_1	643867.Ftrac_2019	1.172e-48	177.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CSH2_k127_5271636_2	926569.ANT_27550	3.916e-56	203.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
CSH2_k127_5271636_1	926569.ANT_04570	1.205e-65	228.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
CSH2_k127_5271636_0	926569.ANT_01840	1.143e-103	343.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CSH2_k127_5273953_1	1121957.ATVL01000010_gene266	6.585e-72	246.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CSH2_k127_5273953_0	1408433.JHXV01000034_gene8	8.09e-88	304.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
CSH2_k127_5282013_2	1123400.KB904776_gene2011	2.786e-20	91.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1RCN9@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,Ferritin-like,zf-CDGSH
CSH2_k127_5282013_0	714943.Mucpa_1515	4.345e-100	334.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CSH2_k127_5282013_3	1279009.ADICEAN_02083	4.706e-11	71.0	2ENX1@1|root,33GHZ@2|Bacteria,4NXFU@976|Bacteroidetes,47WQI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5282013_1	521097.Coch_1559	2.467e-35	138.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia,1EQ8Y@1016|Capnocytophaga	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CSH2_k127_5288746_1	869213.JCM21142_93909	3.942e-06	55.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,47KV8@768503|Cytophagia	976|Bacteroidetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CSH2_k127_5288746_0	926562.Oweho_2197	5.964e-89	317.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_5296020_0	1120966.AUBU01000026_gene524	7.713e-104	356.0	COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes,47PRM@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_5302974_2	797302.Halru_0905	2.679e-18	87.0	COG1926@1|root,arCOG06847@2157|Archaea,2XWRW@28890|Euryarchaeota,23V9R@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CSH2_k127_5302974_1	1341181.FLJC2902T_02510	3.296e-55	203.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,1I19C@117743|Flavobacteriia,2NW0F@237|Flavobacterium	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
CSH2_k127_5302974_0	1453500.AT05_07455	2.277e-151	488.0	COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,1HWJT@117743|Flavobacteriia	976|Bacteroidetes	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CSH2_k127_5303078_0	755732.Fluta_0839	5.087e-159	506.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1HWQC@117743|Flavobacteriia,2PADS@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CSH2_k127_5316173_3	313606.M23134_03831	2.357e-09	68.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47KIJ@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
CSH2_k127_5316173_1	1515613.HQ37_05580	3.86e-58	209.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,2FN1A@200643|Bacteroidia,22WFR@171551|Porphyromonadaceae	976|Bacteroidetes	H	Methyltransferase	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CSH2_k127_5316173_2	1122185.N792_06810	1.238e-39	153.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1X6FT@135614|Xanthomonadales	135614|Xanthomonadales	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CSH2_k127_5316173_0	755732.Fluta_0001	7.588e-248	770.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1HX45@117743|Flavobacteriia,2PAFX@246874|Cryomorphaceae	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CSH2_k127_5323837_1	509635.N824_03085	1.859e-151	499.0	COG0476@1|root,COG0778@1|root,COG0476@2|Bacteria,COG0778@2|Bacteria,4NHWN@976|Bacteroidetes,1IPCC@117747|Sphingobacteriia	976|Bacteroidetes	H	UBA THIF-type NAD FAD binding	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
CSH2_k127_5323837_2	485917.Phep_1529	5.604e-36	142.0	COG3437@1|root,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,1IS8S@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
CSH2_k127_5323837_0	1313301.AUGC01000004_gene2340	5.381e-197	632.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CSH2_k127_5330150_0	760192.Halhy_1230	7.194e-122	410.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5330150_2	756272.Plabr_4196	6.106e-11	71.0	COG1434@1|root,COG1434@2|Bacteria	2|Bacteria	S	Gram-negative-bacterium-type cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CSH2_k127_5330150_1	391587.KAOT1_11967	3.734e-23	105.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I02G@117743|Flavobacteriia	976|Bacteroidetes	O	endonuclease I	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
CSH2_k127_5355267_2	714943.Mucpa_1011	5.238e-30	129.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
CSH2_k127_5355267_1	760192.Halhy_6502	6.551e-84	296.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1IQ9S@117747|Sphingobacteriia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CSH2_k127_5355267_0	1122605.KB893647_gene276	4.716e-84	282.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CSH2_k127_5355377_1	679937.Bcop_1648	3.292e-43	163.0	2A972@1|root,30YBR@2|Bacteria,4PC3Z@976|Bacteroidetes,2FZY2@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5355377_0	1166018.FAES_2815	2.342e-114	379.0	COG3187@1|root,COG3187@2|Bacteria,4NEY0@976|Bacteroidetes,47K7R@768503|Cytophagia	976|Bacteroidetes	O	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3,META
CSH2_k127_5355377_2	575540.Isop_1210	9.355e-05	52.0	COG4447@1|root,COG4447@2|Bacteria,2J1J5@203682|Planctomycetes	203682|Planctomycetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_5363272_2	929556.Solca_0767	4.656e-31	128.0	COG2318@1|root,COG2318@2|Bacteria,4NUTN@976|Bacteroidetes,1IUDR@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CSH2_k127_5363272_0	1278073.MYSTI_00938	9.219e-69	236.0	COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria,438KW@68525|delta/epsilon subdivisions,2X3V9@28221|Deltaproteobacteria,2YX7P@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
CSH2_k127_5363272_1	153721.MYP_592	6.095e-32	137.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,4NES4@976|Bacteroidetes,47XDE@768503|Cytophagia	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CSH2_k127_5383967_1	362418.IW19_00120	4.098e-25	109.0	COG2374@1|root,COG2374@2|Bacteria,4PKDU@976|Bacteroidetes,1IJ8H@117743|Flavobacteriia,2NV5C@237|Flavobacterium	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,LTD
CSH2_k127_5383967_2	504472.Slin_6007	6.157e-21	109.0	COG2374@1|root,COG2374@2|Bacteria,4NURG@976|Bacteroidetes,47P25@768503|Cytophagia	976|Bacteroidetes	G	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_5383967_0	1094466.KQS_13360	7.602e-64	247.0	COG1345@1|root,COG2374@1|root,COG1345@2|Bacteria,COG2374@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,He_PIG,LTD,fn3
CSH2_k127_5397982_0	1408473.JHXO01000010_gene3689	5.928e-177	572.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CSH2_k127_5402264_1	1406840.Q763_09260	2.278e-08	66.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NU73@237|Flavobacterium	976|Bacteroidetes	O	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,MAM,P_proprotein,SBBP,fn3
CSH2_k127_5402264_0	1234364.AMSF01000056_gene1142	9.541e-15	80.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1S2WT@1236|Gammaproteobacteria,1X562@135614|Xanthomonadales	135614|Xanthomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CSH2_k127_5402490_0	502025.Hoch_0876	3.553e-31	142.0	COG3591@1|root,COG3591@2|Bacteria,1NP6U@1224|Proteobacteria,437JH@68525|delta/epsilon subdivisions,2X2TH@28221|Deltaproteobacteria,2YXUB@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CSH2_k127_5402490_1	946362.XP_004992548.1	3.994e-18	100.0	28N08@1|root,2QUJ0@2759|Eukaryota	2759|Eukaryota	-	-	MUC4	GO:0001894,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005102,GO:0005176,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007586,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010669,GO:0012505,GO:0016020,GO:0016021,GO:0016266,GO:0019538,GO:0022600,GO:0023052,GO:0030197,GO:0030277,GO:0031012,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0034645,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048871,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0071704,GO:0071944,GO:0080134,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K22017	-	-	-	-	ko00000,ko04131	-	-	-	NIDO,VWD
CSH2_k127_5403285_1	926549.KI421517_gene3487	5.224e-27	120.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CSH2_k127_5403285_0	1121896.JMLU01000002_gene508	2.056e-37	159.0	COG1629@1|root,COG4771@2|Bacteria,4PKB3@976|Bacteroidetes,1IJ66@117743|Flavobacteriia,2NT2Y@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
CSH2_k127_5412184_1	1237149.C900_04222	1.269e-85	290.0	COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,47NEH@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0471 Di- and tricarboxylate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CSH2_k127_5412184_0	391165.GbCGDNIH1_0532	4.015e-88	308.0	COG4529@1|root,COG4529@2|Bacteria,1MU3U@1224|Proteobacteria,2TUBM@28211|Alphaproteobacteria,2JQK6@204441|Rhodospirillales	204441|Rhodospirillales	S	FAD-NAD(P)-binding	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	NAD_binding_9
CSH2_k127_5412184_2	1307761.L21SP2_1547	9.536e-11	62.0	COG0450@1|root,COG0450@2|Bacteria,2J6HG@203691|Spirochaetes	2|Bacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	lsfA	-	1.11.1.15	ko:K03386,ko:K03665	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko03009,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CSH2_k127_5415784_1	1492738.FEM21_16850	1.345e-11	66.0	COG4775@1|root,COG4775@2|Bacteria,4NFFZ@976|Bacteroidetes,1HXUZ@117743|Flavobacteriia,2NU26@237|Flavobacterium	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_5415784_0	1168289.AJKI01000002_gene2457	5.462e-180	587.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,2G2YH@200643|Bacteroidia,3XISI@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CSH2_k127_5431185_0	1120953.AUBH01000001_gene920	0.0	1193.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria,46979@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CSH2_k127_5431185_1	1189612.A33Q_0026	6.244e-29	125.0	2CE7Q@1|root,32RZA@2|Bacteria,4NSYK@976|Bacteroidetes,47R4R@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5439147_0	926562.Oweho_1478	1.171e-221	693.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,1HWMU@117743|Flavobacteriia,2PA6H@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CSH2_k127_5439147_1	1408433.JHXV01000007_gene2900	3.747e-15	77.0	COG0690@1|root,COG0690@2|Bacteria,4PFHS@976|Bacteroidetes,1IC4N@117743|Flavobacteriia,2PB91@246874|Cryomorphaceae	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CSH2_k127_5439979_0	278957.ABEA03000117_gene1083	6.417e-97	322.0	COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,3K7EJ@414999|Opitutae	414999|Opitutae	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CSH2_k127_5439979_1	755732.Fluta_1420	5.112e-78	282.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2PAGW@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CSH2_k127_5439979_2	518766.Rmar_2191	4.332e-67	240.0	COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,1FJ5D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Phytase-like
CSH2_k127_5443938_0	1121898.Q766_16205	3.402e-132	460.0	COG3291@1|root,COG3291@2|Bacteria,4NEMU@976|Bacteroidetes,1I14C@117743|Flavobacteriia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,F5_F8_type_C,Laminin_G_3,Peptidase_M43
CSH2_k127_5443938_2	755732.Fluta_1682	2.292e-16	94.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_5443938_1	504472.Slin_0182	8.373e-33	149.0	2DN5F@1|root,32VNB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5451752_1	351160.RCIX1753	2.15e-42	168.0	COG3920@1|root,arCOG02335@2157|Archaea	351160.RCIX1753|-	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5451752_0	525257.HMPREF0204_10801	4.718e-46	171.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,1HY9V@117743|Flavobacteriia,3ZPU9@59732|Chryseobacterium	976|Bacteroidetes	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CSH2_k127_5458944_0	1408433.JHXV01000017_gene1589	1.193e-105	367.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,1HX3C@117743|Flavobacteriia,2PA54@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CSH2_k127_5461486_0	485918.Cpin_2595	5.554e-93	314.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CSH2_k127_5474907_1	1191523.MROS_1515	1.484e-61	222.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CSH2_k127_5474907_0	755732.Fluta_3125	9.813e-72	254.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1HXAK@117743|Flavobacteriia,2PAH8@246874|Cryomorphaceae	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein FixG	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CSH2_k127_5482711_0	468059.AUHA01000005_gene2435	1.251e-205	647.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CSH2_k127_5482711_1	1453500.AT05_06865	6.783e-36	141.0	COG1416@1|root,COG1416@2|Bacteria,4NUNC@976|Bacteroidetes,1I4Q6@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
CSH2_k127_5482711_2	1237149.C900_04307	2.477e-11	70.0	28JFD@1|root,2Z99B@2|Bacteria,4NFQJ@976|Bacteroidetes,47NU1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OprD
CSH2_k127_5494651_0	1120966.AUBU01000006_gene3304	1.876e-108	364.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,47N0I@768503|Cytophagia	976|Bacteroidetes	M	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
CSH2_k127_5494651_1	655815.ZPR_0332	9.081e-32	128.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1HXMS@117743|Flavobacteriia	976|Bacteroidetes	C	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CSH2_k127_5511193_2	1121957.ATVL01000007_gene2014	2.27e-19	89.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,47K45@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
CSH2_k127_5511193_0	1035197.HMPREF9999_01241	2.503e-70	245.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,2FMI3@200643|Bacteroidia,1WCQ4@1283313|Alloprevotella	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CSH2_k127_5511193_1	755732.Fluta_2365	2.056e-27	118.0	2C52N@1|root,315JU@2|Bacteria,4PJRQ@976|Bacteroidetes,1IE9T@117743|Flavobacteriia,2PB34@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CSH2_k127_555107_0	1122176.KB903546_gene1003	1.963e-135	442.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1ISZC@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CSH2_k127_555107_1	1131812.JQMS01000001_gene1478	1.15e-30	125.0	COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,1HZEU@117743|Flavobacteriia,2NTUZ@237|Flavobacterium	976|Bacteroidetes	K	TetR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CSH2_k127_5560359_1	717605.Theco_1171	3.465e-08	61.0	COG1846@1|root,COG1846@2|Bacteria,1VA2C@1239|Firmicutes,4HMFU@91061|Bacilli,26YKM@186822|Paenibacillaceae	91061|Bacilli	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,MarR_2
CSH2_k127_5560359_0	1122605.KB893626_gene2492	9.292e-15	86.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,1IUIH@117747|Sphingobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
CSH2_k127_556097_2	755732.Fluta_1182	3.392e-27	114.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,2PABZ@246874|Cryomorphaceae	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CSH2_k127_556097_0	1408433.JHXV01000014_gene3651	0.0	1028.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1HWY0@117743|Flavobacteriia,2PA5H@246874|Cryomorphaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
CSH2_k127_556097_1	1408433.JHXV01000014_gene3650	3.264e-117	392.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1I8RP@117743|Flavobacteriia,2PAPE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
CSH2_k127_556097_3	1408473.JHXO01000001_gene2450	1.221e-13	78.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CSH2_k127_5561839_1	714943.Mucpa_1519	1.734e-116	381.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1IQJQ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CSH2_k127_5561839_0	1408433.JHXV01000032_gene1131	5.332e-141	459.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CSH2_k127_5568743_4	1121957.ATVL01000012_gene815	1.01e-49	179.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,47KB6@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CSH2_k127_5568743_3	1189612.A33Q_0785	4.975e-59	212.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,47Q1Z@768503|Cytophagia	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
CSH2_k127_5568743_2	925409.KI911562_gene1769	4.234e-72	264.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1ISHH@117747|Sphingobacteriia	976|Bacteroidetes	M	SPTR Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
CSH2_k127_5568743_0	929703.KE386491_gene2811	1.229e-156	504.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CSH2_k127_5568743_1	468059.AUHA01000006_gene2993	1.9e-87	306.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,1IQMZ@117747|Sphingobacteriia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CSH2_k127_5572752_3	153721.MYP_3528	1.293e-63	223.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,47MZS@768503|Cytophagia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CSH2_k127_5572752_0	926562.Oweho_1841	3.768e-104	351.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia,2PA7U@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase, LpxD	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CSH2_k127_5572752_2	1408433.JHXV01000009_gene1349	2.231e-85	297.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IMQG@117743|Flavobacteriia,2PBAV@246874|Cryomorphaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
CSH2_k127_5572752_1	1408433.JHXV01000009_gene1254	5.775e-104	350.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes,1I79G@117743|Flavobacteriia,2PAI6@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CSH2_k127_5577771_1	1121895.Q765_19640	2.39e-09	62.0	COG4929@1|root,COG4929@2|Bacteria,4NQB4@976|Bacteroidetes,1I3Q6@117743|Flavobacteriia,2NZ2B@237|Flavobacterium	976|Bacteroidetes	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
CSH2_k127_5577771_0	886379.AEWI01000009_gene707	1.317e-103	349.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia,3XJ5F@558415|Marinilabiliaceae	976|Bacteroidetes	U	YidC periplasmic domain	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CSH2_k127_5589505_3	860228.Ccan_21870	2.788e-22	106.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1HWNA@117743|Flavobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
CSH2_k127_5589505_1	1122176.KB903551_gene4219	8.252e-45	175.0	COG3832@1|root,COG4978@1|root,COG3832@2|Bacteria,COG4978@2|Bacteria	2|Bacteria	J	glyoxalase III activity	glsA	-	3.5.1.2	ko:K01425,ko:K13652	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000,ko03000	-	-	-	GyrI-like,Polyketide_cyc2
CSH2_k127_5589505_2	1453500.AT05_08105	4.27e-25	113.0	2CC29@1|root,32RUM@2|Bacteria,4NS83@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5589505_0	391598.FBBAL38_06505	9.484e-72	246.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia	976|Bacteroidetes	S	zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CSH2_k127_5594320_2	1408433.JHXV01000014_gene3654	8.137e-22	101.0	COG2010@1|root,COG2885@1|root,COG2010@2|Bacteria,COG2885@2|Bacteria,4NKQI@976|Bacteroidetes,1IG0F@117743|Flavobacteriia,2PB3U@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CSH2_k127_5594320_1	755732.Fluta_1181	1.327e-75	258.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia,2PAX8@246874|Cryomorphaceae	976|Bacteroidetes	C	Protein of unknown function (DUF3341)	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CSH2_k127_5594320_0	755732.Fluta_1182	4.102e-212	662.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,2PABZ@246874|Cryomorphaceae	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CSH2_k127_559666_3	485917.Phep_3448	4.236e-72	252.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CSH2_k127_559666_0	755732.Fluta_1605	8.664e-167	538.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,2PAF8@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CSH2_k127_559666_1	926562.Oweho_1808	1.361e-151	491.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2PA4J@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CSH2_k127_559666_2	1408473.JHXO01000008_gene2657	1.573e-85	304.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5599655_2	1270196.JCKI01000002_gene186	1.104e-25	109.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1IUBT@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CSH2_k127_5599655_1	313598.MED152_03975	1.821e-26	108.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia,3VWQU@52959|Polaribacter	976|Bacteroidetes	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CSH2_k127_5599655_4	153721.MYP_1261	2.563e-07	53.0	2E359@1|root,32P2Z@2|Bacteria,4NWAD@976|Bacteroidetes,47SNB@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
CSH2_k127_5599655_0	883096.HMPREF9699_00043	5.084e-129	419.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CSH2_k127_5599655_3	643867.Ftrac_0198	5.198e-22	100.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,47RHF@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
CSH2_k127_5623748_1	1124780.ANNU01000049_gene2213	2.151e-16	91.0	2AAU0@1|root,33Z6J@2|Bacteria,4P4NV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5623748_0	1124780.ANNU01000072_gene1062	1.035e-23	109.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,47XX2@768503|Cytophagia	976|Bacteroidetes	S	Phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
CSH2_k127_5623748_2	644283.Micau_1334	0.0002909	51.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4DAX1@85008|Micromonosporales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CSH2_k127_5630237_2	984262.SGRA_2624	5.563e-07	62.0	COG1572@1|root,COG3209@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CSH2_k127_5630237_1	886377.Murru_2036	7.665e-128	417.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CSH2_k127_5630237_0	929556.Solca_1808	2.796e-139	451.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1INMK@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CSH2_k127_5631548_0	1408433.JHXV01000001_gene715	4.729e-59	214.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1HXYD@117743|Flavobacteriia,2PB24@246874|Cryomorphaceae	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CSH2_k127_5631548_1	1121129.KB903360_gene3405	1.426e-50	196.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,2FU16@200643|Bacteroidia	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
CSH2_k127_5631548_2	643867.Ftrac_2123	1.14e-17	85.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,47K0I@768503|Cytophagia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CSH2_k127_5633479_0	592029.DDD_0457	4.567e-69	240.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1HWSC@117743|Flavobacteriia,3HJFE@363408|Nonlabens	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
CSH2_k127_5633479_1	329726.AM1_1406	2.268e-21	100.0	COG0457@1|root,COG0457@2|Bacteria	329726.AM1_1406|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5644987_3	1395571.TMS3_0114075	1.109e-18	90.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CSH2_k127_5644987_0	525373.HMPREF0766_13751	4.058e-74	258.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CSH2_k127_5644987_4	926562.Oweho_1915	3.84e-11	72.0	COG3291@1|root,COG3291@2|Bacteria,4P5U5@976|Bacteroidetes,1IAAB@117743|Flavobacteriia,2PB83@246874|Cryomorphaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5644987_1	755732.Fluta_1833	8.502e-57	216.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	AhpC-TSA,Omp28
CSH2_k127_5644987_2	926562.Oweho_1917	4.663e-52	190.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,1I33N@117743|Flavobacteriia,2PAUY@246874|Cryomorphaceae	976|Bacteroidetes	CO	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CSH2_k127_5649763_1	1279009.ADICEAN_01645	3.176e-17	85.0	COG1317@1|root,COG1317@2|Bacteria,4PPFZ@976|Bacteroidetes,47YMJ@768503|Cytophagia	976|Bacteroidetes	NU	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
CSH2_k127_5649763_0	755732.Fluta_3616	1.368e-124	411.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,1HWVY@117743|Flavobacteriia,2PAAA@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CSH2_k127_5649763_2	1408433.JHXV01000010_gene535	1.432e-07	56.0	2AAU0@1|root,30Y70@2|Bacteria,4PBYC@976|Bacteroidetes,1ICQX@117743|Flavobacteriia,2PBTU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5663690_2	1313421.JHBV01000021_gene4813	3.008e-59	228.0	COG0604@1|root,COG0604@2|Bacteria,4NPBM@976|Bacteroidetes,1ITI8@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CSH2_k127_5663690_1	518766.Rmar_0832	8.167e-69	258.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,4NK8R@976|Bacteroidetes,1FIRK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
CSH2_k127_5663690_0	1267211.KI669560_gene2048	3.378e-148	475.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1IQV0@117747|Sphingobacteriia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CSH2_k127_5665958_1	1123400.KB904765_gene1396	5.519e-06	60.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
CSH2_k127_5665958_0	867900.Celly_3113	5.649e-39	168.0	COG4625@1|root,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,1I8TP@117743|Flavobacteriia,1F9W2@104264|Cellulophaga	976|Bacteroidetes	S	Ricin-type beta-trefoil lectin domain-like	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
CSH2_k127_5679010_0	1380600.AUYN01000009_gene990	8.178e-55	200.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
CSH2_k127_5686087_2	762903.Pedsa_0781	2.899e-07	57.0	298K1@1|root,3122S@2|Bacteria,4PGXN@976|Bacteroidetes,1IUN3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5686087_0	1408473.JHXO01000006_gene1170	1.333e-106	368.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,2FNT5@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_5686087_1	1121948.AUAC01000002_gene1046	3.518e-37	147.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,43XES@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CSH2_k127_5689265_1	880526.KE386488_gene1511	6.033e-88	302.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia,22UR3@171550|Rikenellaceae	976|Bacteroidetes	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CSH2_k127_5689265_0	398720.MED217_05037	3.839e-136	437.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1HXAZ@117743|Flavobacteriia,2XIWI@283735|Leeuwenhoekiella	976|Bacteroidetes	J	Queuine tRNA-ribosyltransferase	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CSH2_k127_5696778_1	1089547.KB913013_gene3986	4.407e-78	267.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,47KX0@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
CSH2_k127_5696778_2	671143.DAMO_2638	7.131e-49	190.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
CSH2_k127_5696778_0	1034807.FBFL15_0216	7.809e-92	312.0	COG4714@1|root,COG4714@2|Bacteria,4NEVY@976|Bacteroidetes,1I1US@117743|Flavobacteriia,2NV7U@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
CSH2_k127_5696778_3	589865.DaAHT2_1995	8.574e-48	181.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42NQ8@68525|delta/epsilon subdivisions,2WV4B@28221|Deltaproteobacteria,2MNAB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CSH2_k127_5697848_0	1408433.JHXV01000010_gene526	1.418e-50	183.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,2PAX5@246874|Cryomorphaceae	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
CSH2_k127_5697848_1	1121918.ARWE01000001_gene57	3.634e-41	157.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT,DUF4442
CSH2_k127_5697848_2	390989.JOEG01000027_gene2159	3.229e-05	52.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4DE5G@85008|Micromonosporales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CSH2_k127_5704481_1	1234679.BN424_187	2.384e-25	118.0	COG1503@1|root,COG1503@2|Bacteria,1U2HK@1239|Firmicutes,4HWEZ@91061|Bacilli	91061|Bacilli	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5704481_0	1123057.P872_20470	4.642e-104	346.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47TSB@768503|Cytophagia	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CSH2_k127_5760968_0	1150600.ADIARSV_2261	2.386e-65	225.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1IPF3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5760968_2	1121957.ATVL01000011_gene3612	2.751e-13	83.0	28YGT@1|root,2ZKB0@2|Bacteria,4P2Q1@976|Bacteroidetes,47UKX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5760968_1	555793.WSK_2561	9.142e-35	138.0	COG0665@1|root,COG0665@2|Bacteria,1Q6SU@1224|Proteobacteria,2TT4N@28211|Alphaproteobacteria,2K39P@204457|Sphingomonadales	204457|Sphingomonadales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CSH2_k127_5764626_0	927658.AJUM01000022_gene1288	1.565e-56	213.0	2BVGH@1|root,32QVC@2|Bacteria,4NQ4G@976|Bacteroidetes,2G24D@200643|Bacteroidia,3XKJD@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5764626_1	755732.Fluta_0866	1.328e-35	140.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1I2RK@117743|Flavobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
CSH2_k127_5772512_0	1408433.JHXV01000010_gene567	3.433e-206	647.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia,2PA7A@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CSH2_k127_5774492_2	755732.Fluta_2841	4.549e-21	95.0	COG0824@1|root,COG0824@2|Bacteria,4PKAH@976|Bacteroidetes,1I6XR@117743|Flavobacteriia,2PBX6@246874|Cryomorphaceae	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CSH2_k127_5774492_1	1453500.AT05_06190	3.603e-48	177.0	2BJ0K@1|root,32D95@2|Bacteria,4NQN9@976|Bacteroidetes,1I94U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5774492_0	1408473.JHXO01000009_gene3247	6.197e-89	299.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,2FMAA@200643|Bacteroidia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	cap5D	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CSH2_k127_5788069_2	269798.CHU_1890	2.199e-12	67.0	COG0501@1|root,COG0501@2|Bacteria,4NE0J@976|Bacteroidetes,47JGC@768503|Cytophagia	976|Bacteroidetes	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CSH2_k127_5788069_0	1349822.NSB1T_00835	2.632e-126	411.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,2FMWX@200643|Bacteroidia,22W5D@171551|Porphyromonadaceae	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CSH2_k127_5808400_1	1207075.PputUW4_04018	7.533e-73	250.0	COG2519@1|root,COG2519@2|Bacteria,1QU0A@1224|Proteobacteria,1S03F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CSH2_k127_5808400_2	1463821.JOGR01000006_gene2664	3.016e-09	68.0	COG1193@1|root,COG1193@2|Bacteria,2I4QA@201174|Actinobacteria,4EYUQ@85014|Glycomycetales	201174|Actinobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CSH2_k127_5808400_3	1121926.AXWO01000001_gene3728	3.778e-08	56.0	COG1193@1|root,COG1193@2|Bacteria,2I4QA@201174|Actinobacteria,4EYUQ@85014|Glycomycetales	201174|Actinobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CSH2_k127_5808400_0	269798.CHU_3781	3.718e-100	333.0	COG3550@1|root,COG3550@2|Bacteria,4NFYY@976|Bacteroidetes,47MNZ@768503|Cytophagia	976|Bacteroidetes	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
CSH2_k127_5809634_1	1123234.AUKI01000002_gene1801	5.449e-33	143.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
CSH2_k127_5809634_0	1122214.AQWH01000002_gene4244	9.045e-37	144.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,2V9TY@28211|Alphaproteobacteria,2PM3M@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
CSH2_k127_5809634_2	1049564.TevJSym_bm00200	4.128e-16	88.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,1SHID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5821100_0	653733.Selin_1812	7.284e-59	213.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
CSH2_k127_5821100_1	755732.Fluta_0087	5.39e-13	82.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB,TIG
CSH2_k127_5825442_0	491205.JARQ01000003_gene2230	7.099e-63	236.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
CSH2_k127_5828833_0	1185876.BN8_02880	5.046e-102	342.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,47MHR@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CSH2_k127_5828833_1	869213.JCM21142_3856	1.264e-70	255.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,47N7V@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
CSH2_k127_5828833_2	1211813.CAPH01000003_gene1354	1.36e-44	169.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,2FMIG@200643|Bacteroidia,22U97@171550|Rikenellaceae	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CSH2_k127_5862236_0	1121406.JAEX01000016_gene1885	6.027e-131	434.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CSH2_k127_5870639_0	1121373.KB903621_gene1742	1.709e-28	131.0	COG3866@1|root,COG5492@1|root,COG3866@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Alginate_lyase,CBM_6,Cellulase,F5_F8_type_C,Lipase_GDSL_2,Lyase_8,Lyase_8_C,Lyase_8_N,Pec_lyase_C
CSH2_k127_587549_0	929556.Solca_2043	4.027e-122	407.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1INX9@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2270 Permease of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CSH2_k127_587549_1	1408433.JHXV01000036_gene251	2.912e-53	192.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
CSH2_k127_5882183_1	1453500.AT05_05495	5.962e-27	121.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
CSH2_k127_5882183_2	643867.Ftrac_2967	9.332e-07	54.0	2A7GX@1|root,30WEH@2|Bacteria,4P9UT@976|Bacteroidetes,47S3Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5882183_3	1122176.KB903546_gene1027	0.0001022	49.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,MAM,UnbV_ASPIC,VCBS,fn3
CSH2_k127_5882183_0	143224.JQMD01000002_gene3758	7.505e-33	128.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CSH2_k127_5884905_1	1408433.JHXV01000014_gene3647	1.493e-60	220.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia,2PAGI@246874|Cryomorphaceae	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CSH2_k127_5884905_2	1121097.JCM15093_259	1.696e-23	107.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,2FSM9@200643|Bacteroidia,4AK8V@815|Bacteroidaceae	976|Bacteroidetes	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CSH2_k127_5884905_3	929704.Myrod_3068	8.359e-21	99.0	2DD3M@1|root,2ZGBQ@2|Bacteria,4P80Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5884905_0	502025.Hoch_4745	1.481e-102	355.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2YUK3@29|Myxococcales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CSH2_k127_5884905_4	66429.JOFL01000006_gene1895	9.275e-06	52.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	2.3.1.165	ko:K15320	ko01059,ko01130,map01059,map01130	M00829	R07253	RC00004	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ADH_N,ADH_zinc_N,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
CSH2_k127_5888415_0	946077.W5A_12046	6.14e-135	445.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
CSH2_k127_5888941_0	1313301.AUGC01000005_gene273	2.84e-149	481.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes	976|Bacteroidetes	C	alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
CSH2_k127_5902488_0	1313421.JHBV01000003_gene641	1.458e-113	391.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CSH2_k127_5912354_0	313606.M23134_02873	5.525e-183	601.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,47N4Z@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,MAM,TIG,fn3
CSH2_k127_591678_0	1122176.KB903550_gene4281	5.611e-74	259.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
CSH2_k127_591678_2	1121373.KB903622_gene2744	0.0007883	52.0	COG4124@1|root,COG4124@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.1.1.53,3.2.1.78	ko:K01218,ko:K05970,ko:K19355	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_35,Cellulase,Dockerin_1,Glyco_hydro_26,Gram_pos_anchor
CSH2_k127_591678_1	485918.Cpin_4394	5.271e-06	59.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_5918850_0	153721.MYP_4122	7.912e-31	131.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4P04C@976|Bacteroidetes,47TZ7@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
CSH2_k127_5918850_1	742817.HMPREF9449_02758	1.094e-24	110.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,2FPCJ@200643|Bacteroidia,22XVX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
CSH2_k127_5954401_0	1166018.FAES_5474	4.76e-131	435.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,47Y82@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_5960831_1	236814.IX39_00005	1.742e-11	70.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,3ZSPI@59732|Chryseobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
CSH2_k127_5960831_0	1392490.JHZX01000001_gene3178	1.082e-46	184.0	COG2706@1|root,COG4886@1|root,COG2706@2|Bacteria,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CSH2_k127_5975366_6	529818.AMSG_01764T0	1.539e-15	81.0	COG4886@1|root,KOG0619@2759|Eukaryota	2759|Eukaryota	U	regulation of response to stimulus	-	-	-	ko:K19613	ko04014,map04014	-	-	-	ko00000,ko00001	-	-	-	EF-hand_6,LRR_8
CSH2_k127_5975366_5	745411.B3C1_03445	1.792e-32	135.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,1J66U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG3201 Nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
CSH2_k127_5975366_1	1288963.ADIS_2670	9.848e-77	271.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5975366_3	1089547.KB913013_gene1798	1.659e-39	160.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,47QH8@768503|Cytophagia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
CSH2_k127_5975366_0	1356852.N008_08365	1.548e-162	527.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,47MT8@768503|Cytophagia	976|Bacteroidetes	Q	phytoene	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CSH2_k127_5975366_2	760192.Halhy_3092	8.22e-46	174.0	29UQ5@1|root,30G1W@2|Bacteria,4NKX5@976|Bacteroidetes,1IS42@117747|Sphingobacteriia	976|Bacteroidetes	Q	spheroidene monooxygenase	crtA	-	-	-	-	-	-	-	-	-	-	-	DUF3291
CSH2_k127_5975366_4	1279009.ADICEAN_02215	1.526e-35	141.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,47QMU@768503|Cytophagia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CSH2_k127_5975366_7	316067.Geob_0415	3.686e-06	51.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,43TCP@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CSH2_k127_5979566_1	929562.Emtol_1769	1.591e-65	229.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_5979566_0	927658.AJUM01000040_gene922	2.889e-170	565.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,2FM0U@200643|Bacteroidia,3XIWA@558415|Marinilabiliaceae	976|Bacteroidetes	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
CSH2_k127_5979566_3	313598.MED152_06475	1.692e-06	56.0	2C8IP@1|root,32RM9@2|Bacteria,4NSFN@976|Bacteroidetes,1I40E@117743|Flavobacteriia,3VWMF@52959|Polaribacter	976|Bacteroidetes	-	-	mraW	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_5979566_2	1501391.LG35_01525	1.634e-27	113.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia,22U6D@171550|Rikenellaceae	976|Bacteroidetes	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CSH2_k127_5989091_2	985255.APHJ01000019_gene559	1.756e-12	81.0	COG1572@1|root,COG1572@2|Bacteria,4NHWZ@976|Bacteroidetes,1HZTV@117743|Flavobacteriia,2P665@244698|Gillisia	976|Bacteroidetes	E	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,MAM,fn3
CSH2_k127_5989091_1	1111730.ATTM01000007_gene2438	2.253e-19	103.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2NU0I@237|Flavobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
CSH2_k127_5989091_0	1123400.KB904765_gene1396	3.676e-48	195.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
CSH2_k127_5990968_0	1235788.C802_01462	4.68e-115	381.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia,4AN0A@815|Bacteroidaceae	976|Bacteroidetes	C	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CSH2_k127_5990968_1	1089547.KB913013_gene2913	1.956e-61	217.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,47MBS@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
CSH2_k127_5990968_2	1121870.AUAA01000007_gene254	1.884e-37	143.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,3HI9C@358033|Chryseobacterium	976|Bacteroidetes	S	Pfam:DUF59	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CSH2_k127_6067886_1	1197477.IA57_02180	5.922e-12	70.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CSH2_k127_6067886_2	634497.HAH_5051	0.0008826	50.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CSH2_k127_6067886_0	1123278.KB893546_gene5014	2.931e-76	269.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CSH2_k127_6143904_2	760192.Halhy_5162	3.559e-92	310.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1IS63@117747|Sphingobacteriia	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CSH2_k127_6143904_0	1120968.AUBX01000011_gene2988	6.287e-176	561.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,47JAB@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CSH2_k127_6143904_1	1122176.KB903565_gene3311	7.233e-116	402.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1INS7@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
CSH2_k127_6143904_3	1239962.C943_03498	2.085e-11	69.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,47RVQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
CSH2_k127_6148031_1	1408433.JHXV01000016_gene1862	2.241e-26	116.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia,2PB5B@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CSH2_k127_6148031_0	1250232.JQNJ01000001_gene1326	7.733e-141	456.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CSH2_k127_6156147_0	946077.W5A_01135	5.625e-187	599.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_6156147_1	1089547.KB913013_gene1242	4.646e-45	180.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	ALF,LRR_5,PT-HINT,RHS_repeat,Ricin_B_lectin,fn3
CSH2_k127_6156147_2	906888.JCM19314_1933	2.331e-27	126.0	COG1404@1|root,COG1404@2|Bacteria,4NM0U@976|Bacteroidetes,1I0NM@117743|Flavobacteriia,3HKCK@363408|Nonlabens	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_618334_0	1288963.ADIS_2898	2.778e-198	642.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CSH2_k127_618961_2	485918.Cpin_0711	1.323e-34	139.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1IT7Y@117747|Sphingobacteriia	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CSH2_k127_618961_0	251221.35212490	4.052e-62	219.0	COG2173@1|root,COG2173@2|Bacteria,1G56H@1117|Cyanobacteria	1117|Cyanobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
CSH2_k127_618961_1	983544.Lacal_2138	1.52e-44	174.0	COG2378@1|root,COG2378@2|Bacteria,4NI15@976|Bacteroidetes,1HZYZ@117743|Flavobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	WYL
CSH2_k127_6193466_1	246194.CHY_1696	1.204e-08	62.0	COG1476@1|root,COG1476@2|Bacteria,1U4DK@1239|Firmicutes,25JJC@186801|Clostridia,42HF7@68295|Thermoanaerobacterales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CSH2_k127_6193466_0	1121896.JMLU01000005_gene2469	6.073e-40	156.0	COG1525@1|root,COG1525@2|Bacteria,4NT0S@976|Bacteroidetes,1I47N@117743|Flavobacteriia,2NXP5@237|Flavobacterium	976|Bacteroidetes	L	Staphylococcal nuclease homologue	lpxP	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CSH2_k127_6199173_0	1144275.COCOR_04767	8.992e-54	210.0	2DBYS@1|root,2ZBWY@2|Bacteria	2|Bacteria	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc
CSH2_k127_6199173_1	385682.AFSL01000001_gene1998	3.835e-39	159.0	2CAAQ@1|root,331TU@2|Bacteria,4NTCJ@976|Bacteroidetes,2G24Y@200643|Bacteroidia,3XJU8@558415|Marinilabiliaceae	976|Bacteroidetes	S	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CSH2_k127_6201232_0	755732.Fluta_1600	9.171e-66	229.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia,2PAI3@246874|Cryomorphaceae	976|Bacteroidetes	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CSH2_k127_6201232_2	1270196.JCKI01000009_gene3356	1.741e-19	102.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF4347,HemolysinCabind,Peptidase_M43,SdrD_B,fn3
CSH2_k127_6201232_1	1250278.JQNQ01000001_gene1687	1.609e-29	134.0	COG2911@1|root,COG3209@1|root,COG3391@1|root,COG4935@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,SprB
CSH2_k127_6206900_1	1408433.JHXV01000018_gene3850	4.603e-46	178.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4P0PU@976|Bacteroidetes,1IMQT@117743|Flavobacteriia,2PBGH@246874|Cryomorphaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6206900_0	1211813.CAPH01000018_gene1083	3.26e-72	251.0	COG0299@1|root,COG3340@1|root,COG0299@2|Bacteria,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,2FQTC@200643|Bacteroidia,22U8N@171550|Rikenellaceae	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
CSH2_k127_6206900_2	880071.Fleli_1585	7.27e-23	103.0	COG0668@1|root,COG0668@2|Bacteria,4NF28@976|Bacteroidetes,47P8R@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CSH2_k127_6216582_1	1122605.KB893645_gene1022	3.753e-69	239.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CSH2_k127_6216582_0	929556.Solca_3252	1.007e-107	357.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CSH2_k127_6216582_2	700598.Niako_4344	0.0008195	42.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1IU0H@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CSH2_k127_621673_0	755732.Fluta_3944	2.07e-41	164.0	COG1595@1|root,COG1595@2|Bacteria,4NT79@976|Bacteroidetes,1IIVT@117743|Flavobacteriia,2PBR9@246874|Cryomorphaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CSH2_k127_621673_1	1122176.KB903598_gene4699	8.23e-19	99.0	COG1262@1|root,COG1262@2|Bacteria,4NRGU@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_621673_2	926562.Oweho_0417	1.4e-14	82.0	COG2921@1|root,COG2921@2|Bacteria,4PA5G@976|Bacteroidetes,1IGIZ@117743|Flavobacteriia,2PB80@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
CSH2_k127_6218171_0	1453500.AT05_08620	6.014e-93	316.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CSH2_k127_6218171_1	755732.Fluta_3279	5.787e-53	190.0	COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,1IGB0@117743|Flavobacteriia,2PBK6@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CSH2_k127_6219584_0	1111730.ATTM01000008_gene798	3.84e-112	375.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1HXJV@117743|Flavobacteriia,2NT6Z@237|Flavobacterium	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	rfbB	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CSH2_k127_6219584_1	65393.PCC7424_4735	7.687e-34	137.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
CSH2_k127_6220903_1	635013.TherJR_1014	4.64e-40	167.0	COG2949@1|root,COG2949@2|Bacteria,1V1FP@1239|Firmicutes,24HBG@186801|Clostridia,261DH@186807|Peptococcaceae	186801|Clostridia	S	PFAM DUF218 domain	-	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
CSH2_k127_6220903_0	755732.Fluta_0942	5.813e-42	171.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1IKDA@117743|Flavobacteriia,2PB42@246874|Cryomorphaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_6220903_2	984262.SGRA_2219	7.754e-39	151.0	COG2968@1|root,COG2968@2|Bacteria,4NKAQ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
CSH2_k127_6264021_1	1121957.ATVL01000008_gene4149	6.26e-28	129.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,47M73@768503|Cytophagia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CSH2_k127_6264021_0	643867.Ftrac_0939	1.029e-129	424.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CSH2_k127_6264021_2	509635.N824_18465	9.778e-21	94.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,1IST0@117747|Sphingobacteriia	976|Bacteroidetes	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CSH2_k127_6266142_0	529818.AMSG_10339T0	1.812e-07	63.0	KOG4446@1|root,KOG4446@2759|Eukaryota	2759|Eukaryota	S	smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation	MKS1	GO:0000226,GO:0001501,GO:0001578,GO:0001763,GO:0001838,GO:0001841,GO:0001843,GO:0001894,GO:0002009,GO:0003007,GO:0003156,GO:0003205,GO:0003206,GO:0003264,GO:0003266,GO:0003271,GO:0003279,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005829,GO:0005856,GO:0005929,GO:0006996,GO:0007010,GO:0007017,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007275,GO:0007368,GO:0007389,GO:0007399,GO:0007423,GO:0007507,GO:0007568,GO:0007610,GO:0008150,GO:0008340,GO:0008589,GO:0009653,GO:0009790,GO:0009792,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009966,GO:0009987,GO:0010259,GO:0010646,GO:0010669,GO:0014020,GO:0015630,GO:0016020,GO:0016043,GO:0016331,GO:0021915,GO:0022008,GO:0022406,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030030,GO:0030031,GO:0030111,GO:0030154,GO:0030182,GO:0030326,GO:0030537,GO:0031175,GO:0032501,GO:0032502,GO:0032991,GO:0035082,GO:0035107,GO:0035108,GO:0035113,GO:0035148,GO:0035177,GO:0035239,GO:0035295,GO:0035869,GO:0036038,GO:0036064,GO:0042127,GO:0042490,GO:0042592,GO:0042733,GO:0042995,GO:0043009,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043583,GO:0044085,GO:0044422,GO:0044424,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044450,GO:0044458,GO:0044463,GO:0044464,GO:0044782,GO:0045995,GO:0048468,GO:0048513,GO:0048568,GO:0048583,GO:0048598,GO:0048646,GO:0048666,GO:0048699,GO:0048706,GO:0048729,GO:0048731,GO:0048736,GO:0048754,GO:0048839,GO:0048856,GO:0048869,GO:0048871,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051179,GO:0051239,GO:0051640,GO:0051641,GO:0051716,GO:0051960,GO:0060113,GO:0060119,GO:0060122,GO:0060173,GO:0060249,GO:0060271,GO:0060322,GO:0060411,GO:0060429,GO:0060562,GO:0060606,GO:0060756,GO:0060828,GO:0061008,GO:0061009,GO:0061138,GO:0061311,GO:0061822,GO:0065007,GO:0065008,GO:0070925,GO:0071840,GO:0072175,GO:0072359,GO:0090175,GO:0097711,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0140056,GO:1901620,GO:1905330,GO:1905349,GO:1905515,GO:1990403,GO:2000026,GO:2000027,GO:2000050,GO:2000095,GO:2000136,GO:2000826	-	ko:K03030,ko:K19332	ko03050,ko05169,map03050,map05169	M00341	-	-	ko00000,ko00001,ko00002,ko01002,ko03036,ko03051,ko04121	-	-	-	B9-C2
CSH2_k127_6302133_0	1123230.ARQJ01000031_gene2249	6.276e-87	307.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli,4GXA8@90964|Staphylococcaceae	91061|Bacilli	P	symporter activity	sdcS	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CSH2_k127_6304288_0	755732.Fluta_2160	0.0	1172.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia,2PAEA@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CSH2_k127_6304892_1	1408473.JHXO01000001_gene2257	7.288e-79	273.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CSH2_k127_6304892_2	1237149.C900_02028	1.422e-62	219.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
CSH2_k127_6304892_0	1122176.KB903554_gene3837	1.24e-103	357.0	COG1404@1|root,COG1404@2|Bacteria,4NJHT@976|Bacteroidetes,1IUZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CSH2_k127_6304892_4	755732.Fluta_0919	6.033e-32	138.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_15,CHU_C,DUF11,Glyco_hydro_8
CSH2_k127_6304892_3	1121373.KB903620_gene2240	2.994e-54	204.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,47P6I@768503|Cytophagia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_6312232_2	411154.GFO_1838	1.434e-46	181.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
CSH2_k127_6312232_1	927658.AJUM01000022_gene1004	4.086e-82	286.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,2FTFG@200643|Bacteroidia,3XJ5W@558415|Marinilabiliaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_6312232_0	1392490.JHZX01000001_gene869	2.316e-146	501.0	COG1361@1|root,COG4886@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,4NG93@976|Bacteroidetes,1HXFW@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CSH2_k127_6323887_1	1111730.ATTM01000008_gene807	7.454e-73	256.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia,2NSHI@237|Flavobacterium	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CSH2_k127_6323887_0	755732.Fluta_0849	4.527e-75	263.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IKD7@117743|Flavobacteriia,2PBJI@246874|Cryomorphaceae	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
CSH2_k127_6327027_1	1453500.AT05_06735	1.079e-08	65.0	COG2244@1|root,COG2244@2|Bacteria,4NRKF@976|Bacteroidetes	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CSH2_k127_6327027_0	1090319.KE386571_gene2976	6.562e-51	196.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2TTHZ@28211|Alphaproteobacteria,2K41C@204457|Sphingomonadales	204457|Sphingomonadales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6328677_0	1279009.ADICEAN_04219	3.125e-110	362.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CSH2_k127_6328677_1	1123248.KB893337_gene2377	1.303e-13	85.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CSH2_k127_6328677_2	755732.Fluta_1673	8.954e-07	63.0	COG2911@1|root,COG3266@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,4PKFD@976|Bacteroidetes,1IKC5@117743|Flavobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CSH2_k127_6358103_1	700598.Niako_6418	4.307e-75	254.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CSH2_k127_6358103_0	449447.MAE_61060	4.153e-76	269.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
CSH2_k127_6373310_0	1237149.C900_02167	2.27e-79	276.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CSH2_k127_6373310_2	425104.Ssed_2458	0.000268	53.0	2CEKG@1|root,33IBN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6373310_1	485917.Phep_0752	5.21e-64	228.0	28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1ISKT@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4918
CSH2_k127_6376747_0	1122226.AUHX01000007_gene2770	4.519e-184	592.0	COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,1HWQ9@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CSH2_k127_638162_0	1121129.KB903367_gene2764	1.529e-131	434.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,2FMV7@200643|Bacteroidia,22WFA@171551|Porphyromonadaceae	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_638813_0	641524.ADICYQ_0748	8.64e-23	112.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CSH2_k127_6408996_2	926562.Oweho_2802	3.579e-60	220.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_6408996_0	755732.Fluta_2288	1.028e-167	538.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia,2PAKH@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CSH2_k127_6408996_1	755732.Fluta_2289	1.673e-77	267.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia,2PAW7@246874|Cryomorphaceae	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6408996_3	1408433.JHXV01000024_gene1510	1.72e-12	68.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,1HWV7@117743|Flavobacteriia,2PB05@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
CSH2_k127_6411729_0	760192.Halhy_5161	1.743e-87	302.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1IQ77@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
CSH2_k127_6411729_1	997829.HMPREF1121_00317	4.325e-22	98.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,2FM3A@200643|Bacteroidia,22WKN@171551|Porphyromonadaceae	976|Bacteroidetes	S	Dolichyl-phosphate beta-D-mannosyltransferase	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CSH2_k127_642_0	391596.PBAL39_01702	1.948e-297	927.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CSH2_k127_642_1	1165841.SULAR_03063	2.123e-54	197.0	COG2128@1|root,COG2128@2|Bacteria,1PSNE@1224|Proteobacteria,42XCT@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CSH2_k127_6429066_0	1122176.KB903598_gene4712	7.179e-108	380.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
CSH2_k127_6429066_1	1122179.KB890454_gene2959	9.433e-14	85.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cu-binding_MopE,DUF4215,EF-hand_5,P_proprotein,Reprolysin_3,Reprolysin_4
CSH2_k127_6432518_0	468059.AUHA01000004_gene2173	5.758e-119	390.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CSH2_k127_6432518_1	1123277.KB893181_gene2326	7.745e-116	381.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CSH2_k127_6432636_4	1237149.C900_05263	6.607e-38	151.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6432636_0	1121287.AUMU01000003_gene2911	1.184e-99	334.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1HWK6@117743|Flavobacteriia,3ZRAY@59732|Chryseobacterium	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CSH2_k127_6432636_2	1122604.JONR01000020_gene513	1.806e-66	231.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1X6KR@135614|Xanthomonadales	135614|Xanthomonadales	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CSH2_k127_6432636_1	1356852.N008_09225	2.056e-87	296.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia	976|Bacteroidetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CSH2_k127_6432636_3	85643.Tmz1t_1655	5.506e-47	175.0	COG2320@1|root,COG2320@2|Bacteria,1RH46@1224|Proteobacteria,2VWUR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
CSH2_k127_6432636_5	269798.CHU_1238	2.388e-05	49.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Dockerin_1,Malectin
CSH2_k127_6434980_0	1227739.Hsw_0110	2.412e-75	272.0	COG1807@1|root,COG1807@2|Bacteria,4NP7Y@976|Bacteroidetes,47UYH@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6453574_0	1406840.Q763_13335	5.477e-123	403.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia,2NSGC@237|Flavobacterium	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CSH2_k127_6453574_1	1124780.ANNU01000042_gene623	1.351e-71	248.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,47K45@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
CSH2_k127_6464840_0	1347342.BN863_27390	1.087e-116	385.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia	976|Bacteroidetes	H	cytosine-specific methyltransferase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
CSH2_k127_6464840_1	1267211.KI669560_gene1817	9.486e-72	253.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CSH2_k127_6464840_2	755732.Fluta_0530	2.478e-09	64.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia,2PBE6@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CSH2_k127_6471041_1	1123277.KB893177_gene3551	2.367e-67	235.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
CSH2_k127_6471041_0	755732.Fluta_2226	1.302e-218	683.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1HWQ7@117743|Flavobacteriia,2PAEN@246874|Cryomorphaceae	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CSH2_k127_6472966_1	1408473.JHXO01000004_gene163	9.57e-11	67.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,2FM9A@200643|Bacteroidia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CSH2_k127_6472966_0	746697.Aeqsu_1710	4.315e-123	406.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1HXZ2@117743|Flavobacteriia	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
CSH2_k127_650077_1	1408433.JHXV01000002_gene460	4.988e-32	136.0	28MPU@1|root,2ZAYW@2|Bacteria,4PJIE@976|Bacteroidetes,1I9N3@117743|Flavobacteriia,2PC5G@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_650077_0	929556.Solca_4375	3.538e-138	445.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CSH2_k127_6512523_1	1396418.BATQ01000136_gene3662	2.454e-08	66.0	COG3420@1|root,COG3420@2|Bacteria,46T2V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CSH2_k127_6512523_0	1121896.JMLU01000003_gene2211	2.954e-34	134.0	COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1IFBS@117743|Flavobacteriia,2NVEG@237|Flavobacterium	976|Bacteroidetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
CSH2_k127_6522429_0	1121413.JMKT01000014_gene2557	9.519e-16	82.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,2M8CT@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
CSH2_k127_654903_2	1408433.JHXV01000011_gene1999	9.656e-18	93.0	2BV66@1|root,32QJI@2|Bacteria,4PC9C@976|Bacteroidetes,1ICSX@117743|Flavobacteriia,2PC1F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_654903_1	1121481.AUAS01000007_gene1026	2.093e-58	211.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CSH2_k127_654903_0	1408433.JHXV01000010_gene496	1.017e-141	480.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CSH2_k127_6550520_2	1313421.JHBV01000022_gene4705	4.244e-14	83.0	COG1196@1|root,COG2885@1|root,COG1196@2|Bacteria,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CSH2_k127_6550520_0	742726.HMPREF9448_00640	1.083e-57	209.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,2FM94@200643|Bacteroidia,22XNT@171551|Porphyromonadaceae	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CSH2_k127_6550520_1	886377.Murru_3446	1.794e-52	196.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,1HX17@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CSH2_k127_6552290_2	153721.MYP_2461	2.726e-41	158.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,47NH9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6552290_3	1122179.KB890491_gene4529	3.782e-07	60.0	2EN2B@1|root,33FQI@2|Bacteria,4NY51@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6552290_1	234267.Acid_3830	1.575e-60	220.0	COG0395@1|root,COG0395@2|Bacteria,3Y7HR@57723|Acidobacteria	57723|Acidobacteria	G	Inward rectifier potassium channel	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
CSH2_k127_6552290_0	1227739.Hsw_1973	1.892e-151	501.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,47M7Z@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CSH2_k127_6561957_0	194439.CT1622	6.8e-207	649.0	COG0210@1|root,COG1112@1|root,COG0210@2|Bacteria,COG1112@2|Bacteria,1FEFN@1090|Chlorobi	1090|Chlorobi	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
CSH2_k127_6561957_1	616991.JPOO01000001_gene4614	1.277e-48	176.0	2AY99@1|root,31QBJ@2|Bacteria,4NNSA@976|Bacteroidetes,1I2AG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
CSH2_k127_6563951_0	700598.Niako_2068	5.367e-115	396.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	2|Bacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
CSH2_k127_6575726_1	1288963.ADIS_3371	2.745e-14	76.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,47KVF@768503|Cytophagia	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
CSH2_k127_6575726_0	468059.AUHA01000002_gene691	3.488e-141	462.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
CSH2_k127_6588467_0	468059.AUHA01000003_gene1428	1.427e-154	507.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CSH2_k127_6594487_1	411477.PARMER_01030	1.19e-86	298.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
CSH2_k127_6594487_0	1122225.AULQ01000009_gene367	2.811e-88	299.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CSH2_k127_6594487_2	1408433.JHXV01000007_gene2878	1.161e-35	146.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,2PAE6@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CSH2_k127_660159_0	755732.Fluta_2435	1.741e-168	541.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia,2PBAS@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fumarylacetoacetate (FAA) hydrolase family	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
CSH2_k127_660159_1	929556.Solca_2448	4.005e-62	218.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CSH2_k127_6604693_0	391596.PBAL39_06796	5.028e-115	380.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IQ6R@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CSH2_k127_6618944_1	1121373.KB903665_gene3110	1.756e-99	347.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CSH2_k127_6618944_0	1168034.FH5T_01095	7.24e-107	353.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
CSH2_k127_6622828_0	643867.Ftrac_0021	1.285e-188	599.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CSH2_k127_6622828_1	1239962.C943_01492	3.984e-46	174.0	2CCNY@1|root,2Z877@2|Bacteria,4NR3D@976|Bacteroidetes	976|Bacteroidetes	E	CpeT/CpcT family (DUF1001)	-	-	-	-	-	-	-	-	-	-	-	-	CpeT
CSH2_k127_6624813_1	762982.HMPREF9442_02458	1.707e-25	111.0	COG0451@1|root,COG0451@2|Bacteria,4PHT4@976|Bacteroidetes,2FNQG@200643|Bacteroidia	976|Bacteroidetes	M	COG0451 Nucleoside-diphosphate-sugar	-	-	5.1.3.26	ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CSH2_k127_6624813_0	1279009.ADICEAN_00911	4.165e-67	237.0	COG1922@1|root,COG1922@2|Bacteria,4NJGT@976|Bacteroidetes,47NEK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
CSH2_k127_6634984_0	984262.SGRA_1027	8.607e-89	307.0	COG1864@1|root,COG4085@1|root,COG1864@2|Bacteria,COG4085@2|Bacteria,4NFYJ@976|Bacteroidetes,1IY0Z@117747|Sphingobacteriia	976|Bacteroidetes	F	DNA/RNA non-specific endonuclease	nucA_1	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
CSH2_k127_6634984_1	1408433.JHXV01000014_gene3676	2.41e-56	205.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CSH2_k127_6638939_2	529507.PMI1899	7.166e-28	113.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,1RPDH@1236|Gammaproteobacteria,3Z1TI@583|Proteus	1236|Gammaproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CSH2_k127_6638939_0	1122176.KB903549_gene1251	6.234e-92	325.0	COG0729@1|root,COG0729@2|Bacteria,4PKYQ@976|Bacteroidetes,1IS7K@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
CSH2_k127_6638939_1	760192.Halhy_5050	3.597e-71	258.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1INWB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CSH2_k127_6640502_0	391587.KAOT1_19597	1.164e-254	796.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1HXFG@117743|Flavobacteriia	976|Bacteroidetes	HJM	cyanophycin synthetase	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
CSH2_k127_6647425_0	313606.M23134_07479	0.0	1090.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
CSH2_k127_6647425_1	866536.Belba_2617	8.097e-13	73.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
CSH2_k127_66505_0	1408433.JHXV01000016_gene1824	6.841e-150	499.0	COG3291@1|root,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,1I16K@117743|Flavobacteriia,2PC6D@246874|Cryomorphaceae	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43
CSH2_k127_66505_1	755732.Fluta_0810	1.166e-22	102.0	2CKRR@1|root,32SCX@2|Bacteria,4NSV3@976|Bacteroidetes,1I5TY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6651295_0	1121904.ARBP01000002_gene6983	2.542e-143	481.0	COG4206@1|root,COG4206@2|Bacteria,4PKF2@976|Bacteroidetes,47JDS@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_665378_2	1144275.COCOR_06663	3.267e-21	104.0	COG1807@1|root,COG1807@2|Bacteria,1NW9V@1224|Proteobacteria,42ZYW@68525|delta/epsilon subdivisions,2WV64@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_665378_0	485918.Cpin_1916	6.523e-178	571.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IP9D@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CSH2_k127_665378_3	999419.HMPREF1077_01705	7.9e-20	97.0	COG0671@1|root,COG0671@2|Bacteria,4NPUG@976|Bacteroidetes,2FSUS@200643|Bacteroidia,22YR5@171551|Porphyromonadaceae	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CSH2_k127_665378_1	755732.Fluta_1775	2.668e-151	488.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia,2PAMH@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CSH2_k127_6656059_1	561175.KB894093_gene2870	0.0001701	52.0	COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria,4EPB5@85012|Streptosporangiales	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CSH2_k127_6656059_0	1506583.JQJY01000004_gene2921	4.086e-252	807.0	COG1506@1|root,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,1HY8A@117743|Flavobacteriia,2NTHN@237|Flavobacterium	976|Bacteroidetes	E	Peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CSH2_k127_6670693_0	888059.HMPREF9071_0500	1.706e-54	194.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia,1EQGA@1016|Capnocytophaga	976|Bacteroidetes	T	gtp-binding protein typa	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CSH2_k127_6705222_3	1191523.MROS_0708	2.944e-16	86.0	2D6MI@1|root,32TMJ@2|Bacteria	2|Bacteria	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
CSH2_k127_6705222_1	755732.Fluta_2232	2.355e-83	297.0	COG1807@1|root,COG1807@2|Bacteria,4NM44@976|Bacteroidetes,1IF0R@117743|Flavobacteriia,2PBBM@246874|Cryomorphaceae	976|Bacteroidetes	M	Alg9-like mannosyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22
CSH2_k127_6705222_2	1122611.KB903943_gene1488	5.007e-57	208.0	COG0861@1|root,COG0861@2|Bacteria,2GRV3@201174|Actinobacteria,4EIXE@85012|Streptosporangiales	201174|Actinobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CSH2_k127_6705222_0	1408433.JHXV01000010_gene620	2.041e-124	414.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PA4T@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
CSH2_k127_6705682_0	706436.HMPREF9074_07078	3.767e-64	228.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,1EQMY@1016|Capnocytophaga	976|Bacteroidetes	M	peptidylprolyl isomerase	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
CSH2_k127_6705682_2	1121373.KB903621_gene1920	5.78e-18	90.0	2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_10
CSH2_k127_6705682_1	1349785.BAUG01000012_gene921	4.443e-36	139.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1I28N@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CSH2_k127_6716025_0	326427.Cagg_0332	8.264e-64	230.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CSH2_k127_6716025_2	1408433.JHXV01000009_gene1299	1.563e-45	171.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1HXJN@117743|Flavobacteriia,2PAZ7@246874|Cryomorphaceae	976|Bacteroidetes	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CSH2_k127_6716025_1	755732.Fluta_3488	6.827e-60	214.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1HYPS@117743|Flavobacteriia,2PAUN@246874|Cryomorphaceae	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CSH2_k127_6727428_1	1313421.JHBV01000039_gene2629	2.519e-16	93.0	2F1WD@1|root,33UW2@2|Bacteria,4P2AY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_6727428_0	926562.Oweho_2634	2.101e-91	305.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia,2PAAI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CSH2_k127_6749867_0	1356852.N008_06150	8.77e-42	171.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
CSH2_k127_6749867_1	742726.HMPREF9448_02151	3.629e-34	145.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,2FNG9@200643|Bacteroidia,22WTI@171551|Porphyromonadaceae	976|Bacteroidetes	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CSH2_k127_6749867_2	1410613.JNKF01000012_gene1707	8.194e-10	63.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FY5T@200643|Bacteroidia	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CSH2_k127_6749991_0	1408473.JHXO01000001_gene2471	2.92e-58	221.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
CSH2_k127_682255_0	1227739.Hsw_3674	3.611e-97	325.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia	976|Bacteroidetes	DM	TIGRFAM capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
CSH2_k127_682255_1	755732.Fluta_2052	1.756e-59	214.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia,2PATQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CSH2_k127_682255_2	755732.Fluta_2051	2.086e-41	159.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
CSH2_k127_691137_7	1408433.JHXV01000015_gene1734	9e-51	184.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4P03T@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CSH2_k127_691137_3	1408433.JHXV01000015_gene1766	2.181e-73	256.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,1IMR1@117743|Flavobacteriia,2PBIA@246874|Cryomorphaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CSH2_k127_691137_12	1189620.AJXL01000007_gene2354	2.819e-26	115.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2NWNB@237|Flavobacterium	976|Bacteroidetes	L	single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CSH2_k127_691137_9	926562.Oweho_0234	5.639e-33	139.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,2PB27@246874|Cryomorphaceae	976|Bacteroidetes	L	TIGRFAM single stranded DNA-binding protein (ssb)	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CSH2_k127_691137_1	700598.Niako_6051	5.244e-128	416.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
CSH2_k127_691137_11	1089547.KB913013_gene215	4.305e-31	128.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia	976|Bacteroidetes	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
CSH2_k127_691137_4	1406840.Q763_08820	5.325e-65	226.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,1I1AV@117743|Flavobacteriia,2NSXK@237|Flavobacterium	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CSH2_k127_691137_6	1408433.JHXV01000006_gene2708	4.414e-59	211.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia,2PASH@246874|Cryomorphaceae	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CSH2_k127_691137_5	1124780.ANNU01000005_gene2409	3.158e-62	219.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,47KTP@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CSH2_k127_691137_10	755732.Fluta_1898	2.257e-32	129.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1I3VI@117743|Flavobacteriia,2PB4S@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CSH2_k127_691137_0	1550091.JROE01000004_gene1372	4.661e-205	644.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CSH2_k127_691137_8	929562.Emtol_1948	4.907e-45	174.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,47K17@768503|Cytophagia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CSH2_k127_691137_13	755732.Fluta_1909	3.479e-11	70.0	2DNED@1|root,30W9S@2|Bacteria,4P9NX@976|Bacteroidetes,1IE9S@117743|Flavobacteriia,2PBY6@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_691137_2	755732.Fluta_1910	5.707e-76	261.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia,2PAH6@246874|Cryomorphaceae	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CSH2_k127_695522_0	760192.Halhy_5803	3.334e-83	286.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1IPS9@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CSH2_k127_695522_1	1122176.KB903531_gene2945	9.036e-72	272.0	COG1073@1|root,COG1073@2|Bacteria,4NMVZ@976|Bacteroidetes	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_700724_1	1121889.AUDM01000008_gene766	2.481e-19	95.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
CSH2_k127_700724_0	1484460.JSWG01000009_gene314	1.426e-44	179.0	COG3291@1|root,COG4412@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,Cleaved_Adhesin,MAM,fn3
CSH2_k127_707189_2	1408433.JHXV01000006_gene2698	5.155e-38	153.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,1HXJZ@117743|Flavobacteriia,2PAE7@246874|Cryomorphaceae	976|Bacteroidetes	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
CSH2_k127_707189_0	1356852.N008_08000	2.146e-72	254.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CSH2_k127_707189_1	742725.HMPREF9450_00632	8.367e-39	147.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia,22UGY@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CSH2_k127_741839_1	1205753.A989_00025	4.37e-27	117.0	COG0500@1|root,COG2226@2|Bacteria,1NNRW@1224|Proteobacteria,1T8Z5@1236|Gammaproteobacteria,1XBFC@135614|Xanthomonadales	135614|Xanthomonadales	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CSH2_k127_741839_0	1408433.JHXV01000028_gene2119	7.258e-61	224.0	COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
CSH2_k127_745427_0	1313301.AUGC01000017_gene822	2.096e-146	472.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
CSH2_k127_745427_1	929703.KE386491_gene248	1.076e-104	353.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_746038_2	926549.KI421517_gene2586	3.254e-61	220.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,47PN6@768503|Cytophagia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CSH2_k127_746038_1	1122951.ATUE01000007_gene744	1.874e-65	232.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,3NITR@468|Moraxellaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0246 family	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
CSH2_k127_746038_3	1358423.N180_09200	5.48e-29	126.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CSH2_k127_746038_4	1122621.ATZA01000032_gene3029	1.139e-24	113.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1ITC4@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CSH2_k127_746038_0	926549.KI421517_gene3524	2.34e-122	404.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_75392_1	1408433.JHXV01000001_gene651	2.041e-27	123.0	COG2885@1|root,COG2885@2|Bacteria,4PISD@976|Bacteroidetes,1ICSE@117743|Flavobacteriia,2PBZT@246874|Cryomorphaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_75392_0	760192.Halhy_1268	2.888e-35	149.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1IP2E@117747|Sphingobacteriia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CSH2_k127_771218_0	926562.Oweho_2554	8.943e-207	656.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia,2PAIQ@246874|Cryomorphaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CSH2_k127_771218_1	1049564.TevJSym_ad01150	2.009e-18	88.0	COG1215@1|root,COG1215@2|Bacteria,1QVAX@1224|Proteobacteria,1T3H7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.122	ko:K21366	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
CSH2_k127_771908_5	235909.GK3366	0.0002817	44.0	COG5336@1|root,COG5336@2|Bacteria,1VF5M@1239|Firmicutes,4HNYV@91061|Bacilli,1WGVJ@129337|Geobacillus	91061|Bacilli	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
CSH2_k127_771908_0	391596.PBAL39_09461	1.026e-108	367.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CSH2_k127_771908_4	1267211.KI669560_gene2816	7.895e-19	88.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1ITY0@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CSH2_k127_771908_1	445961.IW15_12040	1.487e-34	149.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia,3ZQT0@59732|Chryseobacterium	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CSH2_k127_771908_2	755732.Fluta_1159	1.999e-34	142.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1I28E@117743|Flavobacteriia,2PB3Q@246874|Cryomorphaceae	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CSH2_k127_771908_3	929556.Solca_3293	1.795e-26	109.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CSH2_k127_779287_1	393305.YE1619	1.237e-23	104.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,41FEU@629|Yersinia	1236|Gammaproteobacteria	S	Rhodanase C-terminal	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
CSH2_k127_779287_0	1286632.P278_24780	2.692e-204	641.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CSH2_k127_786729_1	1221522.B723_08425	0.000541	51.0	COG1216@1|root,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,1S5S5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CSH2_k127_786729_0	443143.GM18_0967	1.809e-31	128.0	COG1216@1|root,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,42U4I@68525|delta/epsilon subdivisions,2WPIS@28221|Deltaproteobacteria,43V77@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
CSH2_k127_822210_1	1358423.N180_13145	2.422e-92	307.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1IP9V@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CSH2_k127_822210_0	755732.Fluta_0751	2.13e-137	447.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1HXZ3@117743|Flavobacteriia,2PAK9@246874|Cryomorphaceae	976|Bacteroidetes	F	PFAM Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CSH2_k127_82331_2	755732.Fluta_2914	2.682e-13	82.0	2A94Q@1|root,30Y8X@2|Bacteria,4PC05@976|Bacteroidetes,1ICS0@117743|Flavobacteriia,2PBYD@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_82331_1	755732.Fluta_2913	2.955e-39	166.0	2BJHF@1|root,32DUB@2|Bacteria,4P9RZ@976|Bacteroidetes,1ICNC@117743|Flavobacteriia,2PB7V@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_82331_0	1122621.ATZA01000010_gene131	1.035e-120	394.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CSH2_k127_835116_0	755732.Fluta_0946	9.481e-120	390.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia,2PA5W@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CSH2_k127_835116_1	1453500.AT05_10790	1.553e-49	184.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
CSH2_k127_84869_0	755732.Fluta_3404	6.659e-37	139.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia,2PAGG@246874|Cryomorphaceae	976|Bacteroidetes	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CSH2_k127_84869_1	1227739.Hsw_0565	2.925e-06	57.0	COG3291@1|root,COG4625@1|root,COG3291@2|Bacteria,COG4625@2|Bacteria,4NDZC@976|Bacteroidetes,47YR2@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
CSH2_k127_851529_1	1356852.N008_09830	3.1e-08	57.0	COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,47PA0@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CSH2_k127_851529_0	1279009.ADICEAN_02656	3.498e-41	172.0	COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,47M2B@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CSH2_k127_853793_2	1122226.AUHX01000013_gene1288	3.321e-38	158.0	COG4421@1|root,COG4421@2|Bacteria	2|Bacteria	G	Protein of unknown function (DUF563)	-	-	-	-	-	-	-	-	-	-	-	-	DUF563
CSH2_k127_853793_1	1408433.JHXV01000024_gene1451	5.921e-76	262.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1I2CE@117743|Flavobacteriia,2PBPQ@246874|Cryomorphaceae	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
CSH2_k127_853793_0	1123277.KB893243_gene344	1.919e-188	592.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,47K3S@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CSH2_k127_855296_3	1123400.KB904765_gene1396	6.312e-38	165.0	COG0823@1|root,COG1361@1|root,COG2706@1|root,COG2834@1|root,COG3291@1|root,COG5384@1|root,COG0823@2|Bacteria,COG1361@2|Bacteria,COG2706@2|Bacteria,COG2834@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
CSH2_k127_855296_2	1121889.AUDM01000003_gene2303	3.096e-61	241.0	COG4188@1|root,COG4188@2|Bacteria,4P2MC@976|Bacteroidetes,1I8M4@117743|Flavobacteriia	976|Bacteroidetes	S	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase
CSH2_k127_855296_4	398720.MED217_11469	1.74e-31	131.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1I189@117743|Flavobacteriia,2XJAC@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CSH2_k127_855296_1	1279009.ADICEAN_01682	9.02e-90	304.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,47KKI@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CSH2_k127_855296_0	1279009.ADICEAN_02457	3.409e-108	361.0	COG1840@1|root,COG1840@2|Bacteria,4NJ1Z@976|Bacteroidetes,47MBQ@768503|Cytophagia	976|Bacteroidetes	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6,SBP_bac_8
CSH2_k127_855525_0	1267211.KI669560_gene56	3.197e-40	164.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1IVTD@117747|Sphingobacteriia	976|Bacteroidetes	T	Two component regulator propeller domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CSH2_k127_855525_1	755732.Fluta_1540	6.253e-26	116.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia,2PB44@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CSH2_k127_855525_2	755732.Fluta_1539	1.53e-18	90.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia,2PAM6@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CSH2_k127_87491_1	1408473.JHXO01000010_gene3580	9.562e-103	352.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia	976|Bacteroidetes	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CSH2_k127_87491_0	1121897.AUGO01000001_gene1337	2.876e-107	354.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia,2NSJX@237|Flavobacterium	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CSH2_k127_87491_2	857087.Metme_0507	3.281e-49	183.0	COG2244@1|root,COG2244@2|Bacteria,1R512@1224|Proteobacteria,1RZ0F@1236|Gammaproteobacteria,1XE8D@135618|Methylococcales	135618|Methylococcales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CSH2_k127_880471_1	1279009.ADICEAN_03352	4.947e-27	114.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
CSH2_k127_880471_2	1123037.AUDE01000019_gene3226	4.672e-20	108.0	COG1361@1|root,COG1361@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG
CSH2_k127_880471_0	313606.M23134_02237	5.915e-228	764.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CSH2_k127_882692_0	755732.Fluta_2160	1.23e-197	621.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia,2PAEA@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CSH2_k127_882692_1	1408473.JHXO01000006_gene1416	3.974e-48	176.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CSH2_k127_886913_1	688246.Premu_2832	2.556e-51	185.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CSH2_k127_886913_2	755732.Fluta_0717	3.811e-26	120.0	COG2520@1|root,COG2520@2|Bacteria,4NVH3@976|Bacteroidetes,1IKD5@117743|Flavobacteriia	976|Bacteroidetes	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CSH2_k127_886913_0	1122931.AUAE01000023_gene1521	3.813e-86	289.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,2FMUK@200643|Bacteroidia,22VY0@171551|Porphyromonadaceae	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CSH2_k127_918469_0	1237149.C900_01991	7.084e-83	286.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
CSH2_k127_918469_1	1121904.ARBP01000002_gene6745	1.226e-68	239.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
CSH2_k127_931964_1	755732.Fluta_0767	2.452e-80	272.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1HX1E@117743|Flavobacteriia,2PAN9@246874|Cryomorphaceae	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CSH2_k127_931964_7	1168034.FH5T_12870	7.265e-33	130.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,2FT5V@200643|Bacteroidia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CSH2_k127_931964_4	1408813.AYMG01000023_gene2122	4.34e-56	198.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CSH2_k127_931964_8	643867.Ftrac_3041	3.04e-31	126.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,47VAN@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein S17	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CSH2_k127_931964_9	1121129.KB903360_gene3223	2.488e-14	74.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,2FUJB@200643|Bacteroidia,22Z2N@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CSH2_k127_931964_3	485918.Cpin_1622	6.721e-60	209.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1IRSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CSH2_k127_931964_0	1408473.JHXO01000006_gene1288	4.701e-111	364.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,2FMYX@200643|Bacteroidia	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CSH2_k127_931964_5	1433126.BN938_0976	4.279e-42	158.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,2FS3J@200643|Bacteroidia,22UGT@171550|Rikenellaceae	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CSH2_k127_931964_6	755732.Fluta_0775	1.539e-40	151.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia,2PAXZ@246874|Cryomorphaceae	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CSH2_k127_931964_2	927658.AJUM01000040_gene843	4.96e-72	245.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,2FN89@200643|Bacteroidia,3XJ6G@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal Proteins L2, C-terminal domain	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CSH2_k127_955053_0	313596.RB2501_13549	2.958e-133	439.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1HWWM@117743|Flavobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CSH2_k127_964060_1	1121481.AUAS01000002_gene3219	1.04e-50	188.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,47NZK@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	nhaS3	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CSH2_k127_964060_0	1408473.JHXO01000001_gene2009	2.594e-51	202.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,2FPZX@200643|Bacteroidia	976|Bacteroidetes	KT	PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
CSH2_k127_965237_1	926562.Oweho_2780	5.478e-61	222.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia,2PBC1@246874|Cryomorphaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CSH2_k127_965237_0	926562.Oweho_2781	1.581e-117	387.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia,2PBC9@246874|Cryomorphaceae	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
CSH2_k127_976819_0	1408433.JHXV01000005_gene2524	9.593e-133	444.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_976819_1	709991.Odosp_1285	6.696e-06	52.0	COG1694@1|root,COG1694@2|Bacteria,4NSSM@976|Bacteroidetes,2FTIC@200643|Bacteroidia,230W0@171551|Porphyromonadaceae	976|Bacteroidetes	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CSH2_k127_98296_3	1408473.JHXO01000001_gene2242	3.336e-64	236.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,2G096@200643|Bacteroidia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
CSH2_k127_98296_2	1408433.JHXV01000024_gene1509	1.096e-64	231.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1HX8Y@117743|Flavobacteriia,2PAWJ@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility associated protien GldN	gldN	-	-	-	-	-	-	-	-	-	-	-	-
CSH2_k127_98296_0	1168289.AJKI01000008_gene757	1.461e-169	553.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,2FMY5@200643|Bacteroidia,3XJA4@558415|Marinilabiliaceae	976|Bacteroidetes	S	ABC transporter	yheS_3	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CSH2_k127_98296_1	1443665.JACA01000056_gene3245	2.019e-100	334.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia,2YGVT@290174|Aquimarina	976|Bacteroidetes	S	Ethanolamine utilisation - propanediol utilisation	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CSH2_k127_98296_4	1353276.JADR01000009_gene1940	9.344e-62	217.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
## 1850 queries scanned
## Total time (seconds): 193.35895991325378
## Rate: 9.57 q/s