## Mon Feb 16 10:27:31 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/DEZH2_bin.1.fa -m mmseqs --output DEZH2_bin.1 --output_dir /data/result/bins/wyx/eggqs50+/DEZH2_bin.1 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DEZH2_k127_10111517_0	926561.KB900620_gene3201	1.721e-32	129.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WAJF@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DEZH2_k127_10111517_1	1128427.KB904821_gene4457	8.688e-31	129.0	COG0088@1|root,COG0088@2|Bacteria,1G2H1@1117|Cyanobacteria,1H8AW@1150|Oscillatoriales	1117|Cyanobacteria	J	Forms part of the polypeptide exit tunnel	rpl4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DEZH2_k127_10111517_3	1463820.JOGW01000014_gene504	1.255e-09	63.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DEZH2_k127_10111517_2	1042156.CXIVA_17920	3.506e-29	120.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,36E17@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DEZH2_k127_10247174_0	1278308.KB907081_gene2580	2.438e-102	344.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4FK9T@85023|Microbacteriaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
DEZH2_k127_1028561_1	1278073.MYSTI_01516	1.196e-29	129.0	COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,43CJZ@68525|delta/epsilon subdivisions,2X7UE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	IS66 C-terminal element	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C
DEZH2_k127_1028561_0	215803.DB30_4843	4.865e-31	125.0	COG3436@1|root,COG3436@2|Bacteria,1RHDW@1224|Proteobacteria,4360E@68525|delta/epsilon subdivisions,2X0HX@28221|Deltaproteobacteria,2Z0TS@29|Myxococcales	28221|Deltaproteobacteria	L	High confidence in function and specificity	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
DEZH2_k127_10417540_2	1279038.KB907344_gene3684	4.705e-14	73.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2UBRF@28211|Alphaproteobacteria,2JTYK@204441|Rhodospirillales	204441|Rhodospirillales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DEZH2_k127_10417540_0	1379270.AUXF01000004_gene3023	2.58e-35	138.0	COG0093@1|root,COG0093@2|Bacteria,1ZTPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DEZH2_k127_10417540_1	202752.JL53_14040	9.674e-25	106.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,26KRX@186820|Listeriaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DEZH2_k127_10462216_1	35760.BCHO_1152	1.764e-08	61.0	2DSXT@1|root,32UTZ@2|Bacteria,2GKR7@201174|Actinobacteria,4CZBW@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
DEZH2_k127_10462216_0	1247649.D560_1416	3.179e-61	214.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,3T1H6@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DEZH2_k127_10469370_0	243090.RB818	4.809e-113	368.0	COG3344@1|root,COG3344@2|Bacteria,2IZGP@203682|Planctomycetes	203682|Planctomycetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
DEZH2_k127_10653873_0	126957.SMAR000738-PA	1.469e-19	101.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39TZY@33154|Opisthokonta,3BI15@33208|Metazoa,3CYKV@33213|Bilateria,420TT@6656|Arthropoda	33208|Metazoa	C	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.4.2.29	ko:K15407	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	Exo_endo_phos_2,RVT_1
DEZH2_k127_1079259_0	1185876.BN8_01058	1.807e-31	136.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DEZH2_k127_1387386_0	1395513.P343_17555	1.559e-18	88.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,26P5G@186821|Sporolactobacillaceae	91061|Bacilli	L	GIY-YIG catalytic domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DEZH2_k127_1387386_1	378806.STAUR_5021	1.412e-09	61.0	COG0267@1|root,COG0267@2|Bacteria,1NJ67@1224|Proteobacteria,42V5X@68525|delta/epsilon subdivisions,2WSIR@28221|Deltaproteobacteria,2YW1P@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DEZH2_k127_1387386_2	411901.BACCAC_02675	1.363e-08	59.0	COG4430@1|root,COG4430@2|Bacteria,4NWI7@976|Bacteroidetes,2FN25@200643|Bacteroidia,4AN4M@815|Bacteroidaceae	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
DEZH2_k127_1427507_0	159749.K0RL31	5.078e-36	143.0	COG2801@1|root,KOG0017@2759|Eukaryota,2XF4I@2836|Bacillariophyta	159749.K0RL31|-	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_1493804_0	1392491.JIAE01000001_gene2276	1.657e-11	72.0	COG1595@1|root,COG1595@2|Bacteria,1VCIR@1239|Firmicutes,24NX6@186801|Clostridia,3WK75@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DEZH2_k127_1852978_13	945713.IALB_0773	5.085e-21	96.0	COG0224@1|root,COG0224@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
DEZH2_k127_1852978_0	1131269.AQVV01000011_gene2502	2.193e-174	560.0	COG0056@1|root,COG0056@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DEZH2_k127_1852978_22	1341151.ASZU01000008_gene1449	5.274e-07	57.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,27BZS@186824|Thermoactinomycetaceae	91061|Bacilli	C	ATP synthase delta (OSCP) subunit	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DEZH2_k127_1852978_20	345219.Bcoa_1457	4.136e-07	58.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
DEZH2_k127_1852978_21	552811.Dehly_0546	4.965e-07	54.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi,34DHU@301297|Dehalococcoidia	301297|Dehalococcoidia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DEZH2_k127_1852978_8	525904.Tter_0069	9.674e-31	132.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DEZH2_k127_1852978_17	536232.CLM_1410	3.386e-14	77.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia	186801|Clostridia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DEZH2_k127_1852978_5	1410632.JHWW01000004_gene1654	4.432e-64	240.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,27JZ5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DEZH2_k127_1852978_16	1286170.RORB6_14660	2.441e-14	86.0	COG3344@1|root,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,1S05V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1,Trypsin_2
DEZH2_k127_1852978_10	999423.HMPREF9161_00334	3.706e-28	121.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,4H48E@909932|Negativicutes	909932|Negativicutes	H	cob(I)yrinic acid a,c-diamide adenosyltransferase	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
DEZH2_k127_1852978_3	1111729.ATYV01000004_gene1000	6.112e-89	309.0	COG0438@1|root,COG0438@2|Bacteria,2I9Z9@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DEZH2_k127_1852978_24	634994.GCWU000323_02220	0.0001122	54.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_transf_17,Glyco_transf_4,Stealth_CR1,Stealth_CR2,Stealth_CR3,Sulfotransfer_1
DEZH2_k127_1852978_4	1043205.AFYF01000017_gene1057	1.121e-83	289.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	cpoA	GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576	-	ko:K13678	-	-	R10865	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DEZH2_k127_1852978_14	1122247.C731_3597	2.959e-16	92.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,233U9@1762|Mycobacteriaceae	201174|Actinobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
DEZH2_k127_1852978_18	413404.Rmag_0267	1.345e-12	75.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DEZH2_k127_1852978_12	1229520.ADIAL_1910	4.361e-25	110.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,27G4H@186828|Carnobacteriaceae	91061|Bacilli	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DEZH2_k127_1852978_6	457405.FSDG_01902	3.439e-63	224.0	COG0528@1|root,COG0528@2|Bacteria,3786C@32066|Fusobacteria	32066|Fusobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DEZH2_k127_1852978_1	661478.OP10G_1484	4.825e-105	347.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	xth	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DEZH2_k127_1852978_11	1121342.AUCO01000011_gene2941	2.977e-26	117.0	COG0560@1|root,COG0560@2|Bacteria,1V4PY@1239|Firmicutes,25CGU@186801|Clostridia,36WVR@31979|Clostridiaceae	186801|Clostridia	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
DEZH2_k127_1852978_19	762051.LKI_08035	3.096e-11	75.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,4HG4C@91061|Bacilli,4AYXA@81850|Leuconostocaceae	91061|Bacilli	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
DEZH2_k127_1852978_23	237368.SCABRO_03991	7.419e-05	55.0	COG0515@1|root,COG1470@1|root,COG1572@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM9_1,DUF4114,PEGA,PPC,SASA
DEZH2_k127_1852978_15	69014.TK0843	1.764e-14	78.0	COG0394@1|root,arCOG04425@2157|Archaea,2XXZP@28890|Euryarchaeota,243RE@183968|Thermococci	183968|Thermococci	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
DEZH2_k127_1852978_2	552811.Dehly_0104	1.733e-102	350.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi,34D8Y@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DEZH2_k127_1852978_9	1229517.AMFD01000027_gene540	1.601e-28	119.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
DEZH2_k127_2536067_0	1111728.ATYS01000002_gene2195	6.082e-06	55.0	2DBWK@1|root,2ZBH2@2|Bacteria,1R3JW@1224|Proteobacteria,1S0NQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2612)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2612
DEZH2_k127_2784452_0	657309.BXY_40680	1.078e-06	52.0	2DU31@1|root,33NR4@2|Bacteria,4P27Q@976|Bacteroidetes,2FV73@200643|Bacteroidia,4ASNC@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
DEZH2_k127_2876139_103	1121936.AUHI01000002_gene2544	1.079e-29	124.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSB619.SA_RS10970,iYO844.BSU36820	ATP-synt
DEZH2_k127_2876139_8	1321778.HMPREF1982_04479	7.945e-201	635.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,268HM@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DEZH2_k127_2876139_148	765420.OSCT_1155	1.282e-11	70.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,375QG@32061|Chloroflexia	32061|Chloroflexia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
DEZH2_k127_2876139_169	585502.HMPREF0645_0634	0.0003606	51.0	COG5523@1|root,COG5523@2|Bacteria,4NTWR@976|Bacteroidetes,2FRNK@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
DEZH2_k127_2876139_25	1232430.CAVG010000049_gene470	2.403e-117	385.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,4GX35@90964|Staphylococcaceae	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
DEZH2_k127_2876139_29	929556.Solca_3424	3.692e-100	365.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DEZH2_k127_2876139_106	263358.VAB18032_24070	1.154e-28	124.0	2FDMT@1|root,345P0@2|Bacteria,2HVVS@201174|Actinobacteria,4DHY8@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_91	263358.VAB18032_24070	1.24e-37	153.0	2FDMT@1|root,345P0@2|Bacteria,2HVVS@201174|Actinobacteria,4DHY8@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_157	246200.SPO0294	4.996e-07	60.0	COG1051@1|root,COG1051@2|Bacteria,1MZHT@1224|Proteobacteria,2VEZJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DEZH2_k127_2876139_95	313596.RB2501_16164	4.459e-34	147.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1HX1G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
DEZH2_k127_2876139_131	388413.ALPR1_17968	1.3e-18	91.0	COG3059@1|root,COG3059@2|Bacteria,4P9H9@976|Bacteroidetes,47RAZ@768503|Cytophagia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_81	471852.Tcur_0361	1.053e-41	162.0	COG3568@1|root,COG3568@2|Bacteria,2IK74@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DEZH2_k127_2876139_144	1238182.C882_2911	3.524e-12	75.0	COG1051@1|root,COG1051@2|Bacteria,1N1KH@1224|Proteobacteria,2UA1K@28211|Alphaproteobacteria,2JUF9@204441|Rhodospirillales	204441|Rhodospirillales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DEZH2_k127_2876139_160	1224746.B932_3456	6.787e-06	56.0	COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,2U0WW@28211|Alphaproteobacteria,2JTRW@204441|Rhodospirillales	204441|Rhodospirillales	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
DEZH2_k127_2876139_77	67352.JODS01000005_gene6382	7.194e-44	176.0	COG1554@1|root,COG3266@1|root,COG1554@2|Bacteria,COG3266@2|Bacteria,2I4S5@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_149	485913.Krac_7076	2.317e-11	69.0	COG2204@1|root,COG2204@2|Bacteria,2G9P5@200795|Chloroflexi	200795|Chloroflexi	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
DEZH2_k127_2876139_124	883126.HMPREF9710_02851	5.095e-20	103.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VPAI@28216|Betaproteobacteria,473N9@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PFAM HAMP domain, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, His Kinase A (phosphoacceptor) domain, Two-component sensor kinase N-terminal	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
DEZH2_k127_2876139_74	298654.FraEuI1c_2592	1.795e-47	181.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DEZH2_k127_2876139_51	357808.RoseRS_3858	3.027e-70	258.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
DEZH2_k127_2876139_87	469383.Cwoe_2868	4.599e-39	160.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CR97@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DEZH2_k127_2876139_21	59374.Fisuc_0761	2.196e-125	417.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DEZH2_k127_2876139_114	1069080.KB913028_gene1100	3.608e-26	120.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H1UX@909932|Negativicutes	909932|Negativicutes	S	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DEZH2_k127_2876139_63	882086.SacxiDRAFT_2428	2.899e-54	197.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4DZAV@85010|Pseudonocardiales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
DEZH2_k127_2876139_140	43354.JOIJ01000007_gene1468	2.278e-14	76.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4E4G9@85010|Pseudonocardiales	201174|Actinobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
DEZH2_k127_2876139_12	1120985.AUMI01000011_gene609	3.924e-146	476.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes	909932|Negativicutes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DEZH2_k127_2876139_42	1262915.BN574_00947	2.801e-79	282.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4H359@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DEZH2_k127_2876139_104	313606.M23134_03740	1.179e-29	122.0	COG1694@1|root,COG1694@2|Bacteria,4NX1K@976|Bacteroidetes,47SM1@768503|Cytophagia	976|Bacteroidetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
DEZH2_k127_2876139_83	1406840.Q763_14625	1.446e-41	156.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia,2NWAA@237|Flavobacterium	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DEZH2_k127_2876139_154	388467.A19Y_4507	1.776e-09	65.0	COG0244@1|root,COG0244@2|Bacteria,1G51U@1117|Cyanobacteria,1HATB@1150|Oscillatoriales	1117|Cyanobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DEZH2_k127_2876139_73	468059.AUHA01000003_gene1412	9.077e-48	176.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISYU@117747|Sphingobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
DEZH2_k127_2876139_17	996637.SGM_4119	3.48e-135	436.0	COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DEZH2_k127_2876139_98	996637.SGM_4117	4.329e-33	134.0	2F6XD@1|root,33ZDE@2|Bacteria,2IMMF@201174|Actinobacteria	201174|Actinobacteria	S	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
DEZH2_k127_2876139_152	1283299.AUKG01000002_gene4783	1.023e-09	67.0	COG0537@1|root,COG0537@2|Bacteria,2HQY9@201174|Actinobacteria,4CSQS@84995|Rubrobacteria	84995|Rubrobacteria	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_62	1283299.AUKG01000002_gene4779	6.536e-56	209.0	COG2131@1|root,COG2131@2|Bacteria,2IEBI@201174|Actinobacteria,4CR5J@84995|Rubrobacteria	84995|Rubrobacteria	F	MafB19-like deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
DEZH2_k127_2876139_59	909613.UO65_0497	1.535e-60	215.0	COG0615@1|root,COG0615@2|Bacteria,2IADS@201174|Actinobacteria	201174|Actinobacteria	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
DEZH2_k127_2876139_52	1121926.AXWO01000002_gene1536	1.221e-68	246.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4EXRG@85014|Glycomycetales	201174|Actinobacteria	J	Ribosomal protein L1p/L10e family	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DEZH2_k127_2876139_86	1045009.AFXQ01000003_gene2838	2.957e-40	153.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,1W8YY@1268|Micrococcaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DEZH2_k127_2876139_54	1121423.JONT01000033_gene2660	1.055e-66	231.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,260QW@186807|Peptococcaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
DEZH2_k127_2876139_158	1137271.AZUM01000004_gene4066	5.665e-07	55.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4E5GS@85010|Pseudonocardiales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
DEZH2_k127_2876139_92	194439.CT0658	3.164e-35	153.0	COG5002@1|root,COG5002@2|Bacteria,1FETT@1090|Chlorobi	1090|Chlorobi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS
DEZH2_k127_2876139_94	1122931.AUAE01000012_gene2221	1.146e-34	143.0	COG1451@1|root,COG1451@2|Bacteria,4NNY6@976|Bacteroidetes,2FPFA@200643|Bacteroidia,22Y3J@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
DEZH2_k127_2876139_159	533240.CRC_03145	1.108e-06	58.0	COG4639@1|root,COG4639@2|Bacteria,1G0Y5@1117|Cyanobacteria,1HJS9@1161|Nostocales	1117|Cyanobacteria	K	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,WYL
DEZH2_k127_2876139_50	1101195.Meth11DRAFT_0963	3.354e-71	258.0	COG4938@1|root,COG4938@2|Bacteria,1NEEG@1224|Proteobacteria,2VVZ1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,DUF3696
DEZH2_k127_2876139_65	547163.BN979_04430	1.235e-52	193.0	COG4322@1|root,COG4322@2|Bacteria,2IKYT@201174|Actinobacteria,238E6@1762|Mycobacteriaceae	201174|Actinobacteria	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
DEZH2_k127_2876139_147	926556.Echvi_3660	1.03e-11	71.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	nudI	-	3.6.1.55	ko:K03574,ko:K12944	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DEZH2_k127_2876139_13	1116232.AHBF01000162_gene4173	4.193e-142	460.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
DEZH2_k127_2876139_134	479434.Sthe_2414	4.587e-17	93.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CUB,Calx-beta,DUF11,PA14,SdrD_B,VWA_2
DEZH2_k127_2876139_19	1008457.BAEX01000018_gene1835	2.046e-130	429.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia,47IT0@76831|Myroides	976|Bacteroidetes	E	Histidinol dehydrogenase	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DEZH2_k127_2876139_166	1196323.ALKF01000163_gene4908	0.000124	52.0	COG0454@1|root,COG0454@2|Bacteria,1UJEF@1239|Firmicutes,4IT6Z@91061|Bacilli,2778J@186822|Paenibacillaceae	91061|Bacilli	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DEZH2_k127_2876139_96	204669.Acid345_3681	2.257e-33	132.0	COG0139@1|root,COG0139@2|Bacteria,3Y4SN@57723|Acidobacteria,2JJIB@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	-	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
DEZH2_k127_2876139_168	1217718.ALOU01000037_gene2106	0.0003323	51.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,1K1IG@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM PfkB domain protein	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DEZH2_k127_2876139_165	67281.JNZZ01000043_gene3576	2.879e-05	53.0	COG0454@1|root,COG0456@2|Bacteria,2IG1Q@201174|Actinobacteria,41AYW@629295|Streptomyces griseus group	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DEZH2_k127_2876139_151	634497.HAH_1652	4.813e-10	70.0	arCOG02888@1|root,arCOG02888@2157|Archaea,2XTJG@28890|Euryarchaeota,23SIG@183963|Halobacteria	183963|Halobacteria	E	Succinylglutamate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
DEZH2_k127_2876139_121	292459.STH2696	2.508e-22	104.0	COG1611@1|root,COG1611@2|Bacteria,1V2D7@1239|Firmicutes,24KYJ@186801|Clostridia	186801|Clostridia	S	TIGRFAM TIGR00725 family protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DEZH2_k127_2876139_117	1089553.Tph_c08880	6.131e-25	107.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,42F6A@68295|Thermoanaerobacterales	186801|Clostridia	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
DEZH2_k127_2876139_36	525904.Tter_0658	2.182e-87	297.0	COG0040@1|root,COG0040@2|Bacteria,2NPA9@2323|unclassified Bacteria	2|Bacteria	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_1909	HisG,HisG_C
DEZH2_k127_2876139_16	1540257.JQMW01000009_gene2799	3.269e-138	452.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,36FA9@31979|Clostridiaceae	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DEZH2_k127_2876139_39	765952.PUV_00570	4.76e-81	279.0	COG0109@1|root,COG0109@2|Bacteria,2JFWP@204428|Chlamydiae	204428|Chlamydiae	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DEZH2_k127_2876139_122	1444711.CCJF01000005_gene1099	1.62e-20	95.0	COG3125@1|root,COG3125@2|Bacteria,2JGFM@204428|Chlamydiae	204428|Chlamydiae	C	Prokaryotic Cytochrome C oxidase subunit IV	cyoD	-	-	ko:K02300	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX4_pro
DEZH2_k127_2876139_53	1444711.CCJF01000005_gene1100	2.596e-68	237.0	COG1845@1|root,COG1845@2|Bacteria,2JFY3@204428|Chlamydiae	204428|Chlamydiae	C	Cytochrome c oxidase subunit III	cyoC	-	-	ko:K02299	ko00190,ko01100,map00190,map01100	M00417	-	-	ko00000,ko00001,ko00002	3.D.4.5	-	-	COX3
DEZH2_k127_2876139_3	1444712.BN1013_00113	1.412e-289	901.0	COG0843@1|root,COG0843@2|Bacteria,2JFT7@204428|Chlamydiae	204428|Chlamydiae	C	Cytochrome C and Quinol oxidase polypeptide I	cyoB	-	1.10.3.10	ko:K02298	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX1
DEZH2_k127_2876139_30	1437425.CSEC_2435	3.501e-93	314.0	COG1622@1|root,COG1622@2|Bacteria,2JFR4@204428|Chlamydiae	204428|Chlamydiae	C	COX Aromatic Rich Motif	cyoA	-	1.10.3.10	ko:K02297	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX2,COX_ARM
DEZH2_k127_2876139_80	1382306.JNIM01000001_gene2557	1.692e-42	171.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DEZH2_k127_2876139_41	1239962.C943_01799	2.701e-79	280.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DEZH2_k127_2876139_14	411464.DESPIG_00921	7.149e-142	461.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DEZH2_k127_2876139_20	717606.PaecuDRAFT_3423	2.448e-126	428.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,4HBR5@91061|Bacilli,26TY6@186822|Paenibacillaceae	91061|Bacilli	G	glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
DEZH2_k127_2876139_170	873448.STRPO_1343	0.0005298	45.0	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DEZH2_k127_2876139_150	644282.Deba_1392	3.249e-10	69.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1R7IR@1224|Proteobacteria,42MT7@68525|delta/epsilon subdivisions,2WITW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_1,TPR_14,TPR_2,TPR_8
DEZH2_k127_2876139_138	445973.CLOBAR_02495	6.677e-16	87.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,25E6M@186801|Clostridia,25QW5@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
DEZH2_k127_2876139_71	311424.DhcVS_1156	8.99e-50	188.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,34D96@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DEZH2_k127_2876139_46	156978.CIMIT_02470	3.961e-75	264.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,22JQ4@1653|Corynebacteriaceae	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DEZH2_k127_2876139_112	243365.CV_0902	5.248e-27	119.0	COG2173@1|root,COG2173@2|Bacteria,1RBFI@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
DEZH2_k127_2876139_55	1124780.ANNU01000081_gene2570	3.988e-66	242.0	COG1626@1|root,COG1626@2|Bacteria,4PKJT@976|Bacteroidetes,47W3S@768503|Cytophagia	976|Bacteroidetes	G	glycoside hydrolase family 37	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
DEZH2_k127_2876139_155	929703.KE386491_gene1223	2.113e-08	62.0	COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DEZH2_k127_2876139_109	699218.HMPREF0889_1263	4.501e-28	117.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4H4GK@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DEZH2_k127_2876139_78	1089439.KB902240_gene740	1.191e-43	164.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,460KF@72273|Thiotrichales	72273|Thiotrichales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DEZH2_k127_2876139_111	382640.BT_1493	2.976e-27	116.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,48U2E@772|Bartonellaceae	28211|Alphaproteobacteria	J	structural constituent of ribosome	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
DEZH2_k127_2876139_48	446469.Sked_29460	3.043e-72	254.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DEZH2_k127_2876139_67	324602.Caur_2395	6.544e-51	187.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi,375G2@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DEZH2_k127_2876139_93	1458462.JNLK01000001_gene974	1.089e-34	136.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,27M7M@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DEZH2_k127_2876139_88	118173.KB235914_gene4000	2.165e-38	147.0	COG0099@1|root,COG0099@2|Bacteria,1G5S9@1117|Cyanobacteria,1HB1Z@1150|Oscillatoriales	1117|Cyanobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DEZH2_k127_2876139_145	1501268.EW14_1896	4.625e-12	66.0	COG0257@1|root,COG0257@2|Bacteria,1GRE2@1117|Cyanobacteria,1MP6X@1212|Prochloraceae	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
DEZH2_k127_2876139_110	679897.HMU10340	2.904e-27	111.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2YPS3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DEZH2_k127_2876139_38	479434.Sthe_1056	4.965e-85	299.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DEZH2_k127_2876139_125	926550.CLDAP_03910	6.585e-20	96.0	COG0200@1|root,COG0200@2|Bacteria,2G6XY@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DEZH2_k127_2876139_79	937777.Deipe_3054	7.101e-43	165.0	COG0098@1|root,COG0098@2|Bacteria,1WJD4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DEZH2_k127_2876139_119	1123313.ATUT01000003_gene768	6.972e-24	104.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,3VQGV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
DEZH2_k127_2876139_60	398767.Glov_1361	3.952e-60	212.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,43SZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DEZH2_k127_2876139_102	644282.Deba_2924	2.912e-31	126.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DEZH2_k127_2876139_99	926549.KI421517_gene250	4.933e-33	129.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,47QB0@768503|Cytophagia	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DEZH2_k127_2876139_66	221027.JO40_02245	4.98e-51	187.0	COG0094@1|root,COG0094@2|Bacteria,2J5DT@203691|Spirochaetes	203691|Spirochaetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DEZH2_k127_2876139_120	1550091.JROE01000004_gene1349	1.784e-22	102.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1ISXS@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DEZH2_k127_2876139_68	1408422.JHYF01000014_gene294	9.032e-51	183.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,36IUH@31979|Clostridiaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DEZH2_k127_2876139_126	1123313.ATUT01000003_gene775	7.041e-20	93.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,3VR8U@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DEZH2_k127_2876139_167	273526.SMDB11_3787	0.0001727	48.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DEZH2_k127_2876139_69	391615.ABSJ01000049_gene1561	2.43e-50	182.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1JA22@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DEZH2_k127_2876139_56	562970.Btus_0159	1.867e-63	224.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,2788F@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DEZH2_k127_2876139_116	1123306.KB904342_gene32	1.402e-25	110.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DEZH2_k127_2876139_100	1469557.JSWF01000035_gene1024	2.473e-32	127.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DEZH2_k127_2876139_34	941824.TCEL_01105	1.665e-88	300.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,36E17@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DEZH2_k127_2876139_153	357804.Ping_3522	1.376e-09	63.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,2QI6R@267894|Psychromonadaceae	1236|Gammaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DEZH2_k127_2876139_84	555088.DealDRAFT_1522	1.733e-41	161.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42JTY@68298|Syntrophomonadaceae	186801|Clostridia	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DEZH2_k127_2876139_61	574087.Acear_0162	3.342e-57	207.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WAJF@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DEZH2_k127_2876139_76	935866.JAER01000022_gene2925	4.81e-44	171.0	COG2340@1|root,COG5479@1|root,COG2340@2|Bacteria,COG5479@2|Bacteria,2GMJR@201174|Actinobacteria,4DRUQ@85009|Propionibacteriales	201174|Actinobacteria	M	Protein of unknown function (DUF3152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3152
DEZH2_k127_2876139_70	1211819.CALK01000050_gene1520	8.259e-50	190.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,3VR2J@526524|Erysipelotrichia	526524|Erysipelotrichia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
DEZH2_k127_2876139_35	1397278.AYMV01000027_gene708	1.617e-87	304.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4FNC8@85023|Microbacteriaceae	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
DEZH2_k127_2876139_97	1499680.CCFE01000011_gene578	2.725e-33	139.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	vanYB	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
DEZH2_k127_2876139_156	1120950.KB892708_gene4428	1.017e-07	57.0	2E9C2@1|root,333JS@2|Bacteria,2IQ5V@201174|Actinobacteria,4DSCX@85009|Propionibacteriales	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
DEZH2_k127_2876139_128	1123392.AQWL01000007_gene957	3.484e-19	94.0	COG0406@1|root,COG0406@2|Bacteria,1QNM0@1224|Proteobacteria,2WB46@28216|Betaproteobacteria,1KS21@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
DEZH2_k127_2876139_130	515620.EUBELI_00350	1.299e-18	92.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
DEZH2_k127_2876139_136	1209072.ALBT01000009_gene3063	5.736e-17	87.0	2CH3Z@1|root,32RP9@2|Bacteria,1MZF8@1224|Proteobacteria,1S8TF@1236|Gammaproteobacteria,1FHBJ@10|Cellvibrio	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
DEZH2_k127_2876139_90	1306174.JODP01000006_gene3568	6.105e-38	145.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DEZH2_k127_2876139_9	1246955.MCYN_0828	2.49e-181	574.0	COG0050@1|root,COG0050@2|Bacteria,3WSWU@544448|Tenericutes	544448|Tenericutes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DEZH2_k127_2876139_4	387092.NIS_0272	4.124e-264	830.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DEZH2_k127_2876139_82	352165.HMPREF7215_0920	1.071e-41	158.0	COG0049@1|root,COG0049@2|Bacteria,3TAVX@508458|Synergistetes	508458|Synergistetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DEZH2_k127_2876139_64	1123405.AUMM01000026_gene2181	6.315e-53	189.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,26NS1@186821|Sporolactobacillaceae	91061|Bacilli	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DEZH2_k127_2876139_1	309801.trd_0990	0.0	1114.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,27Y0B@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DEZH2_k127_2876139_0	498761.HM1_1370	0.0	1154.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DEZH2_k127_2876139_45	596330.HMPREF0628_0087	4.496e-76	259.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,22GK5@1570339|Peptoniphilaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DEZH2_k127_2876139_58	1094508.Tsac_1413	6.565e-61	227.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,42FDH@68295|Thermoanaerobacterales	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
DEZH2_k127_2876139_37	414996.IL38_17240	4.045e-85	298.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,409ZU@622450|Actinopolysporales	201174|Actinobacteria	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DEZH2_k127_2876139_163	202955.BBND01000004_gene54	2.496e-05	49.0	2A3SE@1|root,30SAA@2|Bacteria,1QQHN@1224|Proteobacteria,1RT5P@1236|Gammaproteobacteria,3NS9N@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_108	1223544.GSI01S_15_01250	1.873e-28	121.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4GDSX@85026|Gordoniaceae	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
DEZH2_k127_2876139_10	273068.TTE1492	1.448e-153	509.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,42ES5@68295|Thermoanaerobacterales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DEZH2_k127_2876139_135	1385511.N783_17290	5.213e-17	91.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,4IESH@91061|Bacilli,2Y9FK@289201|Pontibacillus	91061|Bacilli	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
DEZH2_k127_2876139_33	665952.HMPREF1015_00565	8.133e-89	307.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
DEZH2_k127_2876139_31	926550.CLDAP_15350	2.551e-89	326.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
DEZH2_k127_2876139_72	1382359.JIAL01000001_gene909	1.404e-49	192.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria,2JKNZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
DEZH2_k127_2876139_24	1127695.HMPREF9163_02292	4.817e-119	397.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H2G5@909932|Negativicutes	909932|Negativicutes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
DEZH2_k127_2876139_57	312284.A20C1_00876	3.101e-63	229.0	COG1196@1|root,COG1196@2|Bacteria,2GYKI@201174|Actinobacteria	201174|Actinobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_6	1410665.JNKR01000001_gene251	1.892e-230	739.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4H2CB@909932|Negativicutes	909932|Negativicutes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DEZH2_k127_2876139_32	479434.Sthe_1255	7.24e-89	306.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi,27XPJ@189775|Thermomicrobia	189775|Thermomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DEZH2_k127_2876139_7	1123306.KB904340_gene384	2.009e-216	699.0	COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli	91061|Bacilli	E	aminopeptidase	pepN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
DEZH2_k127_2876139_143	1122239.AULS01000001_gene1753	7.544e-14	82.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4FPTI@85023|Microbacteriaceae	201174|Actinobacteria	L	nucleic acid phosphodiester bond hydrolysis	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DEZH2_k127_2876139_89	1280946.HY29_02010	2.56e-38	155.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,43XM1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DEZH2_k127_2876139_118	521098.Aaci_1366	4.322e-24	108.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DEZH2_k127_2876139_115	888056.HMPREF9062_0525	4.621e-26	115.0	2AIAF@1|root,318RA@2|Bacteria,2HKYP@201174|Actinobacteria,4D628@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_15	1121355.KB903377_gene323	9.87e-141	456.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,22KVK@1653|Corynebacteriaceae	201174|Actinobacteria	C	Malic enzyme	mez_1	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
DEZH2_k127_2876139_44	1234364.AMSF01000088_gene2721	4.492e-76	277.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1X36S@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	xpsE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
DEZH2_k127_2876139_85	1445613.JALM01000016_gene6094	7.432e-41	160.0	COG0566@1|root,COG0566@2|Bacteria,2HRZ2@201174|Actinobacteria,4EBF4@85010|Pseudonocardiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
DEZH2_k127_2876139_129	1262449.CP6013_2119	5.46e-19	98.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia,36FMJ@31979|Clostridiaceae	186801|Clostridia	M	PFAM Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
DEZH2_k127_2876139_2	1158318.ATXC01000002_gene1498	2.942e-293	940.0	COG0587@1|root,COG0587@2|Bacteria,2G3PZ@200783|Aquificae	200783|Aquificae	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
DEZH2_k127_2876139_171	1274374.CBLK010000082_gene3958	0.0007066	46.0	2EAMZ@1|root,334QH@2|Bacteria,1VGIW@1239|Firmicutes,4HPFD@91061|Bacilli,26XNT@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_162	37659.JNLN01000001_gene1259	1.578e-05	52.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes	1239|Firmicutes	S	Gas vesicle protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
DEZH2_k127_2876139_123	1105031.HMPREF1141_0623	3.153e-20	93.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia,36N4Z@31979|Clostridiaceae	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
DEZH2_k127_2876139_49	1476973.JMMB01000007_gene3228	7.517e-72	253.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,25QH5@186804|Peptostreptococcaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DEZH2_k127_2876139_26	177437.HRM2_31420	5.568e-113	381.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MIIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
DEZH2_k127_2876139_18	313612.L8106_00745	8.707e-135	444.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1H6YQ@1150|Oscillatoriales	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DEZH2_k127_2876139_141	1304284.L21TH_1654	2.943e-14	76.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,36MP3@31979|Clostridiaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
DEZH2_k127_2876139_5	479434.Sthe_0796	7.417e-259	812.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DEZH2_k127_2876139_101	314345.SPV1_10621	1.038e-31	132.0	COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria	1224|Proteobacteria	S	YHS domain	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	YHS
DEZH2_k127_2876139_132	1408254.T458_22045	1.319e-18	97.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,26UNI@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DEZH2_k127_2876139_75	429009.Adeg_0056	3.076e-44	173.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,42EMP@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ketose-bisphosphate aldolase, class-II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
DEZH2_k127_2876139_11	1121924.ATWH01000014_gene3393	2.779e-147	473.0	COG3958@1|root,COG3958@2|Bacteria,2I8VM@201174|Actinobacteria,4FKW5@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DEZH2_k127_2876139_28	1121924.ATWH01000014_gene3392	2.514e-109	361.0	COG3959@1|root,COG3959@2|Bacteria,2GJ6M@201174|Actinobacteria,4FN7S@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DEZH2_k127_2876139_127	255470.cbdbA627	2.128e-19	96.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi,34D4E@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DEZH2_k127_2876139_107	888050.HMPREF9004_0255	1.601e-28	119.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,4D5T9@85005|Actinomycetales	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
DEZH2_k127_2876139_23	309799.DICTH_1453	3.797e-120	395.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DEZH2_k127_2876139_22	748671.LCRIS_00984	6.629e-123	412.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
DEZH2_k127_2876139_133	1210884.HG799462_gene8982	6.384e-18	89.0	2DQH0@1|root,336T7@2|Bacteria,2J54X@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_2876139_43	546262.NEICINOT_03625	1.333e-76	261.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,2KQJT@206351|Neisseriales	206351|Neisseriales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
DEZH2_k127_2876139_113	926567.TheveDRAFT_1652	7.518e-27	118.0	COG0584@1|root,COG0584@2|Bacteria,3TCIM@508458|Synergistetes	508458|Synergistetes	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DEZH2_k127_2876139_40	398511.BpOF4_05340	1.841e-80	278.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DEZH2_k127_2876139_161	1347392.CCEZ01000009_gene2337	8.642e-06	52.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia	186801|Clostridia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DEZH2_k127_2876139_142	1283299.AUKG01000001_gene2457	4.164e-14	79.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4CQX5@84995|Rubrobacteria	84995|Rubrobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
DEZH2_k127_2876139_146	1033739.CAEU01000020_gene2857	5.243e-12	72.0	COG1051@1|root,COG1051@2|Bacteria,1V6ZQ@1239|Firmicutes,4HIQM@91061|Bacilli,26FWB@186818|Planococcaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DEZH2_k127_2876139_27	545693.BMQ_4742	1.291e-110	388.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DEZH2_k127_2876139_105	997296.PB1_15114	1.096e-28	118.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus	91061|Bacilli	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
DEZH2_k127_2876139_47	313606.M23134_03579	7.476e-73	258.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DEZH2_k127_2876139_137	1123020.AUIE01000020_gene1080	1.804e-16	82.0	COG0431@1|root,COG0431@2|Bacteria,1RGV1@1224|Proteobacteria,1S7M4@1236|Gammaproteobacteria,1YEAA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DEZH2_k127_3302361_0	1122603.ATVI01000002_gene2134	6.753e-128	413.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1X48A@135614|Xanthomonadales	135614|Xanthomonadales	J	GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DEZH2_k127_3309255_3	388051.AUFE01000009_gene1861	8.284e-07	57.0	2EE0G@1|root,337V9@2|Bacteria,1RG3P@1224|Proteobacteria,2W3I0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3277
DEZH2_k127_3309255_0	1120985.AUMI01000001_gene2168	4.086e-41	168.0	2DBB8@1|root,2Z867@2|Bacteria,1V7Q5@1239|Firmicutes,4H63P@909932|Negativicutes	909932|Negativicutes	S	Protein of unknown function (DUF3383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3383
DEZH2_k127_3309255_1	1444712.BN1013_02408	4.149e-36	150.0	COG4834@1|root,COG4834@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2184)	Z012_11565	-	-	-	-	-	-	-	-	-	-	-	DUF2184
DEZH2_k127_3309255_2	1120980.JQKH01000068_gene550	1.795e-17	92.0	COG3566@1|root,COG3566@2|Bacteria,1RAWB@1224|Proteobacteria,2VR16@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09960	-	-	-	-	ko00000	-	-	-	DUF2213
DEZH2_k127_3581531_0	32057.KB217480_gene8171	2.762e-24	108.0	29921@1|root,2ZW5I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3834129_0	984262.SGRA_2716	3.591e-136	440.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DEZH2_k127_390715_0	760192.Halhy_1832	4.996e-54	202.0	COG3210@1|root,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	976|Bacteroidetes	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	SprB
DEZH2_k127_390715_1	1122179.KB890458_gene646	1.415e-12	77.0	COG3210@1|root,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	2|Bacteria	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Haemagg_act,He_PIG,RHS_repeat
DEZH2_k127_3975723_0	1341157.RF007C_11465	2.413e-20	100.0	COG1208@1|root,COG1208@2|Bacteria,1UPGU@1239|Firmicutes,25C21@186801|Clostridia,3WSAE@541000|Ruminococcaceae	186801|Clostridia	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3975723_1	246197.MXAN_1203	6.393e-16	85.0	COG0749@1|root,COG0749@2|Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
DEZH2_k127_4129314_0	497964.CfE428DRAFT_6407	3.162e-13	79.0	COG1409@1|root,COG3210@1|root,COG3291@1|root,COG3866@1|root,COG5276@1|root,COG1409@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3866@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	G	Pectate lyase	pnlA	-	4.2.2.10	ko:K01732,ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000	-	-	-	Big_5,Haemagg_act,HemolysinCabind,LVIVD,Laminin_G_3,PKD,Pec_lyase_C
DEZH2_k127_4274353_19	471874.PROSTU_00109	2.993e-20	91.0	29XIP@1|root,30J9M@2|Bacteria,1QGXJ@1224|Proteobacteria,1TEDR@1236|Gammaproteobacteria,3ZADK@586|Providencia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_13	1115515.EV102420_46_00003	2.127e-32	126.0	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,1S8U2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_26	762966.HMPREF9439_01518	7.974e-10	59.0	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria	1224|Proteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_40	253839.SSNG_03736	0.0008835	45.0	29WRJ@1|root,30ICM@2|Bacteria,2H09C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_35	1187848.AJYQ01000148_gene1828	2.419e-05	46.0	2AWRM@1|root,31NNJ@2|Bacteria,1QKD5@1224|Proteobacteria,1TIGU@1236|Gammaproteobacteria,1XZ3R@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_16	244582.JQAK01000022_gene652	7.691e-24	103.0	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_28	498761.HM1_3125	1.231e-08	59.0	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_27	1121439.dsat_2904	1.481e-09	60.0	2AZ0G@1|root,31R6J@2|Bacteria,1NMSQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_34	1403313.AXBR01000014_gene2201	1.815e-05	49.0	2BTFW@1|root,32NN5@2|Bacteria,1UB53@1239|Firmicutes,4IMHN@91061|Bacilli,1ZK6C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_14	1122619.KB892364_gene1142	3.111e-30	119.0	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,2W66T@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_30	1120951.AUBG01000003_gene2734	2.137e-08	56.0	2DMHR@1|root,32RMI@2|Bacteria,4NS7M@976|Bacteroidetes,1I3YS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_17	498761.HM1_3148	1.16e-22	100.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_38	509191.AEDB02000042_gene4877	0.0001011	44.0	2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,24W9H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_12	1382230.ASAP_2763	1.207e-34	137.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_20	296587.XP_002507531.1	3.557e-19	92.0	COG1963@1|root,2QPKC@2759|Eukaryota,37KTI@33090|Viridiplantae,34I5A@3041|Chlorophyta	3041|Chlorophyta	S	Phosphatidic acid Phosphatase-related protein	PAP2	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
DEZH2_k127_4274353_0	479434.Sthe_1721	1.373e-267	848.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,27Y2U@189775|Thermomicrobia	189775|Thermomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DEZH2_k127_4274353_1	1391646.AVSU01000021_gene3243	1.2e-236	748.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,25QWZ@186804|Peptostreptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DEZH2_k127_4274353_39	765913.ThidrDRAFT_3118	0.0001109	55.0	COG1361@1|root,COG2931@1|root,COG3055@1|root,COG3291@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,1QYMF@1224|Proteobacteria,1T3SH@1236|Gammaproteobacteria,1WYUQ@135613|Chromatiales	135613|Chromatiales	Q	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214
DEZH2_k127_4274353_4	1047013.AQSP01000118_gene1252	7.327e-96	349.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_8	1219065.VPR01S_02_03360	9.446e-45	171.0	COG1434@1|root,COG1434@2|Bacteria,1N4TG@1224|Proteobacteria,1RSJ5@1236|Gammaproteobacteria,1XWHV@135623|Vibrionales	135623|Vibrionales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DEZH2_k127_4274353_6	1032480.MLP_30100	2.114e-52	201.0	COG2730@1|root,COG2730@2|Bacteria,2I8WH@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4,3.2.1.58	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	-	R00308,R03115,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DEZH2_k127_4274353_3	309801.trd_A0017	5.727e-140	461.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DEZH2_k127_4274353_9	585199.HMPREF0577_0731	1.497e-41	159.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4D49S@85005|Actinomycetales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DEZH2_k127_4274353_29	519441.Smon_0491	1.946e-08	57.0	COG0291@1|root,COG0291@2|Bacteria,37B4G@32066|Fusobacteria	32066|Fusobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
DEZH2_k127_4274353_10	1231190.NA8A_13774	1.785e-40	152.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,43JP5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
DEZH2_k127_4274353_15	928724.SacglDRAFT_00778	1.198e-29	129.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
DEZH2_k127_4274353_11	1150469.RSPPHO_03011	1.087e-34	143.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2TRIF@28211|Alphaproteobacteria,2JRZ0@204441|Rhodospirillales	204441|Rhodospirillales	S	COG1994 Zn-dependent proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
DEZH2_k127_4274353_23	1045009.AFXQ01000028_gene1861	2.197e-12	68.0	COG0227@1|root,COG0227@2|Bacteria,2IQAT@201174|Actinobacteria,1W9UQ@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
DEZH2_k127_4274353_24	643648.Slip_2317	4.026e-12	74.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,24AHX@186801|Clostridia,42K8K@68298|Syntrophomonadaceae	186801|Clostridia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
DEZH2_k127_4274353_36	207559.Dde_3684	3.361e-05	53.0	COG2345@1|root,COG2345@2|Bacteria,1RFJP@1224|Proteobacteria,43BW8@68525|delta/epsilon subdivisions,2X76Y@28221|Deltaproteobacteria,2MH4E@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4274353_7	1122919.KB905558_gene1314	1.621e-47	181.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,26RAP@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
DEZH2_k127_4274353_18	525904.Tter_0337	1.405e-20	94.0	COG3695@1|root,COG3695@2|Bacteria,2NRVD@2323|unclassified Bacteria	2|Bacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
DEZH2_k127_4274353_2	485913.Krac_3454	1.761e-195	627.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
DEZH2_k127_4274353_31	2074.JNYD01000035_gene6683	3.81e-08	61.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4E2M8@85010|Pseudonocardiales	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
DEZH2_k127_4274353_5	1123013.AUIC01000007_gene192	6.493e-77	264.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_4296543_2	1227261.HMPREF0043_01904	1.17e-14	75.0	COG0842@1|root,COG0842@2|Bacteria,2IB08@201174|Actinobacteria,4D4NV@85005|Actinomycetales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
DEZH2_k127_4296543_1	1227261.HMPREF0043_01904	2.997e-23	102.0	COG0842@1|root,COG0842@2|Bacteria,2IB08@201174|Actinobacteria,4D4NV@85005|Actinomycetales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
DEZH2_k127_4296543_0	1227261.HMPREF0043_01903	1.747e-110	362.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4D63Y@85005|Actinomycetales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DEZH2_k127_4415918_0	580332.Slit_1366	7.442e-99	326.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,44V9Z@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DEZH2_k127_4430800_0	243090.RB818	2.709e-77	265.0	COG3344@1|root,COG3344@2|Bacteria,2IZGP@203682|Planctomycetes	203682|Planctomycetes	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
DEZH2_k127_4513047_0	926550.CLDAP_38000	5.585e-56	208.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
DEZH2_k127_4569312_0	408672.NBCG_04645	2.852e-162	521.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4DP4H@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
DEZH2_k127_4600298_0	452659.RrIowa_0145	1.047e-55	202.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,47ET1@766|Rickettsiales	766|Rickettsiales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DEZH2_k127_493364_0	1120953.AUBH01000007_gene1896	6.905e-113	369.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,4648C@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DEZH2_k127_5153192_2	1123013.AUIC01000007_gene192	4.064e-94	320.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5153192_10	455436.DS989811_gene1936	0.0004736	42.0	2DPZZ@1|root,3345G@2|Bacteria,1N8ZZ@1224|Proteobacteria,1SFRJ@1236|Gammaproteobacteria,468HG@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5153192_9	517417.Cpar_0013	2.175e-07	63.0	COG0760@1|root,COG0760@2|Bacteria,1FDC8@1090|Chlorobi	1090|Chlorobi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N,SurA_N_3
DEZH2_k127_5153192_5	1121272.KB903289_gene4134	6.424e-44	168.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4DDFU@85008|Micromonosporales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
DEZH2_k127_5153192_6	272563.CD630_13320	1.885e-42	165.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25QTP@186804|Peptostreptococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DEZH2_k127_5153192_4	1120973.AQXL01000121_gene41	1.294e-52	197.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,277XE@186823|Alicyclobacillaceae	91061|Bacilli	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DEZH2_k127_5153192_7	1173264.KI913949_gene2992	1.383e-31	134.0	COG1989@1|root,COG1989@2|Bacteria,1FZZA@1117|Cyanobacteria,1H7ST@1150|Oscillatoriales	1117|Cyanobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	hofD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
DEZH2_k127_5153192_3	477974.Daud_0970	9.458e-82	286.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,2600P@186807|Peptococcaceae	186801|Clostridia	U	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DEZH2_k127_5153192_1	469381.Dpep_2276	2.965e-116	385.0	COG2805@1|root,COG2805@2|Bacteria,3T9Z7@508458|Synergistetes	508458|Synergistetes	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DEZH2_k127_5153192_0	768670.Calni_1648	1.847e-128	431.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
DEZH2_k127_5153192_8	751945.Theos_0439	4.731e-23	111.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DEZH2_k127_5271000_0	63737.Npun_F0076	1.483e-26	120.0	COG3385@1|root,COG3385@2|Bacteria,1G27F@1117|Cyanobacteria,1HMUZ@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
DEZH2_k127_5316827_0	28444.JODQ01000001_gene2375	4.959e-93	315.0	COG1653@1|root,COG1653@2|Bacteria,2I9M7@201174|Actinobacteria,4EQ61@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
DEZH2_k127_5417266_1	575540.Isop_2425	6.605e-15	89.0	COG5283@1|root,COG5283@2|Bacteria,2J1F5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5417266_4	1392838.AWNM01000071_gene634	0.0003244	48.0	2E6HM@1|root,3314W@2|Bacteria,1NC0Z@1224|Proteobacteria,2W3P1@28216|Betaproteobacteria,3T7YR@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5417266_2	395965.Msil_3086	4.445e-13	80.0	2DC0H@1|root,2ZC7P@2|Bacteria,1RB77@1224|Proteobacteria,2U8GK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5417266_3	477184.KYC_17477	2.955e-11	69.0	2E5CW@1|root,3304Y@2|Bacteria,1N8PX@1224|Proteobacteria,2W4WM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5417266_0	1005994.GTGU_04658	2.464e-19	101.0	COG3299@1|root,COG3299@2|Bacteria,1MW2X@1224|Proteobacteria,1RP82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
DEZH2_k127_5427990_2	479435.Kfla_2105	2.955e-18	91.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4DPKU@85009|Propionibacteriales	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
DEZH2_k127_5427990_0	378806.STAUR_0913	9.933e-53	207.0	COG0553@1|root,COG0553@2|Bacteria,1QA6T@1224|Proteobacteria,434VA@68525|delta/epsilon subdivisions,2WZ6F@28221|Deltaproteobacteria,2Z1F9@29|Myxococcales	28221|Deltaproteobacteria	KL	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5427990_3	246197.MXAN_1823	3.679e-05	52.0	2CGYE@1|root,3355Z@2|Bacteria,1NJNH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5427990_1	378806.STAUR_0916	1.567e-24	119.0	COG0749@1|root,COG0749@2|Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
DEZH2_k127_5517049_0	938289.CAJN020000003_gene941	0.000207	52.0	COG0063@1|root,COG0736@1|root,COG0063@2|Bacteria,COG0736@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,267N9@186813|unclassified Clostridiales	186801|Clostridia	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
DEZH2_k127_5589367_0	1038867.AXAY01000025_gene2031	5.591e-52	189.0	COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2TSGI@28211|Alphaproteobacteria,3K0UF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Phage portal protein, lambda family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal_2
DEZH2_k127_5589367_1	1472716.KBK24_0121720	5.814e-27	118.0	COG0616@1|root,COG0616@2|Bacteria,1QGPW@1224|Proteobacteria,2VJ0N@28216|Betaproteobacteria,1K5G3@119060|Burkholderiaceae	28216|Betaproteobacteria	OU	Peptidase family S49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S49
DEZH2_k127_565827_79	1392491.JIAE01000001_gene2529	2.461e-17	81.0	2DPII@1|root,3327T@2|Bacteria,1VHT9@1239|Firmicutes,24RHP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_56	698769.JFBD01000024_gene1884	1.895e-36	139.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_76	316274.Haur_2664	1.314e-20	107.0	COG2866@1|root,COG2866@2|Bacteria,2GB4F@200795|Chloroflexi,3751R@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DEZH2_k127_565827_70	1304866.K413DRAFT_4828	3.787e-22	106.0	COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,24AJH@186801|Clostridia,36FQS@31979|Clostridiaceae	186801|Clostridia	GK	ROK family	gmuE	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
DEZH2_k127_565827_28	469383.Cwoe_2872	5.942e-69	247.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CPF8@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
DEZH2_k127_565827_5	246194.CHY_1766	2.869e-140	465.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,42EP2@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
DEZH2_k127_565827_58	710687.KI912270_gene4975	2.383e-33	133.0	2B9ZR@1|root,323DD@2|Bacteria,2H80V@201174|Actinobacteria,23E7J@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_42	1140001.I571_02720	1.647e-52	196.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,4AZB6@81852|Enterococcaceae	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
DEZH2_k127_565827_65	1382356.JQMP01000004_gene676	3.222e-27	118.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi,27YB2@189775|Thermomicrobia	189775|Thermomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DEZH2_k127_565827_12	1123302.KB904170_gene356	6.037e-106	367.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DEZH2_k127_565827_97	1463909.KL585951_gene2390	1.513e-05	55.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
DEZH2_k127_565827_88	926556.Echvi_2851	3.932e-12	70.0	COG0640@1|root,COG0640@2|Bacteria,4NS23@976|Bacteroidetes,47UMU@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_11	696369.KI912183_gene1647	9.982e-108	368.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
DEZH2_k127_565827_69	66869.JNXG01000001_gene3656	1.853e-22	102.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,41AMJ@629295|Streptomyces griseus group	201174|Actinobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
DEZH2_k127_565827_68	521096.Tpau_3396	5.853e-25	111.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0000166,GO:0003674,GO:0003824,GO:0004017,GO:0004550,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006165,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009141,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032261,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043173,GO:0044209,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
DEZH2_k127_565827_31	1341151.ASZU01000021_gene1315	4.357e-63	225.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,27B7R@186824|Thermoactinomycetaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DEZH2_k127_565827_18	1382306.JNIM01000001_gene41	3.384e-85	298.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DEZH2_k127_565827_9	293826.Amet_2873	1.287e-120	400.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,36F0J@31979|Clostridiaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DEZH2_k127_565827_48	1302863.I872_08865	1.048e-42	160.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli	91061|Bacilli	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
DEZH2_k127_565827_0	1121877.JQKF01000002_gene1700	0.0	1025.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
DEZH2_k127_565827_37	446469.Sked_25470	7.966e-60	214.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
DEZH2_k127_565827_95	1079460.ATTQ01000002_gene5193	4.137e-08	61.0	COG0454@1|root,COG0456@2|Bacteria,1RIF2@1224|Proteobacteria,2UK9Y@28211|Alphaproteobacteria,4BF37@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DEZH2_k127_565827_3	889378.Spiaf_2477	1.068e-234	758.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
DEZH2_k127_565827_20	31964.CMS0896	3.547e-83	298.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria,4FKPX@85023|Microbacteriaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
DEZH2_k127_565827_67	383372.Rcas_0237	1.293e-25	111.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,377H1@32061|Chloroflexia	32061|Chloroflexia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
DEZH2_k127_565827_81	525904.Tter_0488	5.244e-16	81.0	COG0261@1|root,COG0261@2|Bacteria,2NPSX@2323|unclassified Bacteria	2|Bacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
DEZH2_k127_565827_22	926567.TheveDRAFT_1776	3.614e-80	275.0	COG1192@1|root,COG1192@2|Bacteria,3T9TR@508458|Synergistetes	508458|Synergistetes	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DEZH2_k127_565827_39	580327.Tthe_2746	8.013e-58	211.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DEZH2_k127_565827_78	1462527.CCDM010000002_gene1206	1.247e-18	93.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,23K9E@182709|Oceanobacillus	91061|Bacilli	U	Signal peptidase, peptidase S26	sipT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DEZH2_k127_565827_75	1232436.CAPF01000092_gene269	6.839e-21	108.0	COG1316@1|root,COG1316@2|Bacteria,2HF18@201174|Actinobacteria,4CUEQ@84998|Coriobacteriia	84998|Coriobacteriia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
DEZH2_k127_565827_36	515635.Dtur_1305	3.579e-60	222.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin,Trypsin_2
DEZH2_k127_565827_49	1177179.A11A3_10047	3.625e-42	166.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1XJ61@135619|Oceanospirillales	135619|Oceanospirillales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
DEZH2_k127_565827_10	1379281.AVAG01000042_gene829	3.174e-112	372.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2M8U2@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DEZH2_k127_565827_64	1260251.SPISAL_01415	4.787e-28	118.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,1X2GZ@135613|Chromatiales	135613|Chromatiales	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DEZH2_k127_565827_34	2340.JV46_15070	4.612e-61	219.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1J5AE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DEZH2_k127_565827_38	562970.Btus_1526	3.897e-58	210.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,27828@186823|Alicyclobacillaceae	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DEZH2_k127_565827_53	522772.Dacet_0496	7.592e-38	148.0	COG0233@1|root,COG0233@2|Bacteria,2GFEE@200930|Deferribacteres	200930|Deferribacteres	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DEZH2_k127_565827_29	525909.Afer_1266	1.107e-63	226.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DEZH2_k127_565827_45	324602.Caur_3574	1.41e-47	185.0	COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi,3753D@32061|Chloroflexia	32061|Chloroflexia	M	SMART PDZ DHR GLGF domain protein	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
DEZH2_k127_565827_87	679935.Alfi_0510	7.35e-13	78.0	COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,2FP40@200643|Bacteroidia	976|Bacteroidetes	S	CAAX amino terminal protease family	sagE	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DEZH2_k127_565827_17	702450.CUW_0569	4.419e-91	314.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,3VNZ1@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b,tRNA_edit
DEZH2_k127_565827_54	1403313.AXBR01000008_gene646	1.14e-36	143.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DEZH2_k127_565827_14	748449.Halha_0145	2.225e-103	354.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3WAA0@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
DEZH2_k127_565827_94	1042326.AZNV01000024_gene2364	8.907e-09	68.0	COG0642@1|root,COG2205@2|Bacteria,1RCSX@1224|Proteobacteria,2U5U3@28211|Alphaproteobacteria,4B9U2@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	divJ	-	2.7.13.3	ko:K11357	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DEZH2_k127_565827_26	1215915.BN193_08200	2.638e-76	262.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HCWT@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DEZH2_k127_565827_44	1158612.I580_03068	9.157e-49	192.0	COG4591@1|root,COG4591@2|Bacteria,1UIYX@1239|Firmicutes,4ISXR@91061|Bacilli,4B5XG@81852|Enterococcaceae	91061|Bacilli	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DEZH2_k127_565827_19	909663.KI867150_gene1412	1.211e-84	296.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MQ90@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
DEZH2_k127_565827_98	420890.LCGL_0354	3.306e-05	53.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,1YBKG@1357|Lactococcus	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
DEZH2_k127_565827_2	748449.Halha_2230	2.094e-240	770.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WAH3@53433|Halanaerobiales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
DEZH2_k127_565827_92	604331.AUHY01000050_gene2193	7.928e-10	71.0	COG0612@1|root,COG0612@2|Bacteria,1WIJ5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DEZH2_k127_565827_27	1121342.AUCO01000022_gene2999	4.236e-76	273.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,36DUY@31979|Clostridiaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
DEZH2_k127_565827_46	543632.JOJL01000021_gene1064	4.177e-47	186.0	COG1365@1|root,COG1365@2|Bacteria,2GR2T@201174|Actinobacteria,4D8TQ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_15	326427.Cagg_2879	3.062e-103	347.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,374TI@32061|Chloroflexia	32061|Chloroflexia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DEZH2_k127_565827_21	935839.JAGJ01000022_gene3496	5.678e-81	275.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4F3YD@85017|Promicromonosporaceae	201174|Actinobacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DEZH2_k127_565827_71	700015.Corgl_0645	1.951e-21	106.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CU8U@84998|Coriobacteriia	84998|Coriobacteriia	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
DEZH2_k127_565827_93	1499967.BAYZ01000133_gene19	8.004e-09	67.0	COG0739@1|root,COG3942@1|root,COG0739@2|Bacteria,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	CHAP,DUF4185,GBS_Bsp-like,Peptidase_M23
DEZH2_k127_565827_25	545697.HMPREF0216_01235	1.105e-76	271.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,36DGU@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DEZH2_k127_565827_72	1007104.SUS17_414	2.283e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2K0QB@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_565827_80	1322246.BN4_11303	3.71e-17	83.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MCGT@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DEZH2_k127_565827_84	529709.PYCH_10530	6.488e-14	84.0	COG1041@1|root,arCOG00047@2157|Archaea,2Y2EJ@28890|Euryarchaeota,2432J@183968|Thermococci	183968|Thermococci	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
DEZH2_k127_565827_32	1101188.KI912155_gene1498	2.539e-62	228.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
DEZH2_k127_565827_40	1321786.HMPREF1992_01129	1.123e-57	214.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes	1239|Firmicutes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
DEZH2_k127_565827_82	9365.XP_007520636.1	1.606e-15	83.0	COG0500@1|root,KOG4058@2759|Eukaryota,39SC5@33154|Opisthokonta,3BDSU@33208|Metazoa,3CX4A@33213|Bilateria,488H1@7711|Chordata,4931R@7742|Vertebrata,3J86W@40674|Mammalia	33208|Metazoa	Q	positive regulation of sensory perception of pain	FAM173B	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016020,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0019866,GO:0030061,GO:0031090,GO:0031644,GO:0031646,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044057,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0048518,GO:0050789,GO:0051239,GO:0051240,GO:0051930,GO:0051931,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1904058	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_89	1121926.AXWO01000001_gene3401	9.681e-12	74.0	COG0642@1|root,COG2205@2|Bacteria,2GJMV@201174|Actinobacteria,4EYCY@85014|Glycomycetales	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DEZH2_k127_565827_99	1501230.ET33_08910	4.835e-05	51.0	COG0745@1|root,COG0745@2|Bacteria,1VTZW@1239|Firmicutes,4HVB2@91061|Bacilli,26UYI@186822|Paenibacillaceae	91061|Bacilli	T	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_565827_85	255470.cbdbA557	7.671e-14	80.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,34CSZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
DEZH2_k127_565827_4	351627.Csac_1956	3.732e-142	463.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DEZH2_k127_565827_90	324602.Caur_0878	2.488e-11	73.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria,2G5KN@200795|Chloroflexi,374UQ@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
DEZH2_k127_565827_91	626887.J057_08051	1.797e-10	64.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,468GN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
DEZH2_k127_565827_73	645991.Sgly_1731	3.638e-21	104.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,2607D@186807|Peptococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DEZH2_k127_565827_74	317936.Nos7107_0713	6.202e-21	100.0	2CCI4@1|root,30BPJ@2|Bacteria,1GAR7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_61	111781.Lepto7376_1176	6.072e-30	121.0	COG2343@1|root,COG2343@2|Bacteria,1G7U6@1117|Cyanobacteria,1HC91@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG2343 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
DEZH2_k127_565827_83	756499.Desde_2296	1.863e-15	82.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,262YN@186807|Peptococcaceae	186801|Clostridia	KT	Stress-responsive transcriptional regulator	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
DEZH2_k127_565827_50	1123023.JIAI01000019_gene2227	1.421e-40	158.0	COG4894@1|root,COG4894@2|Bacteria,2IH17@201174|Actinobacteria,4E2YX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_60	56780.SYN_00670	5.262e-33	137.0	COG2865@1|root,COG2865@2|Bacteria,1RDDZ@1224|Proteobacteria,42ZRV@68525|delta/epsilon subdivisions,2WUWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_63	1122602.ATXP01000023_gene578	3.24e-28	122.0	COG3102@1|root,COG3102@2|Bacteria	2|Bacteria	S	YecM protein	yecM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09907	-	-	-	-	ko00000	-	-	-	YecM
DEZH2_k127_565827_100	521011.Mpal_0631	0.0001875	53.0	arCOG11067@1|root,arCOG11067@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF4868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4868
DEZH2_k127_565827_66	648885.KB316285_gene2276	1.023e-25	111.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,1JRU9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
DEZH2_k127_565827_62	67257.JODR01000009_gene289	2.483e-29	126.0	COG1437@1|root,COG1437@2|Bacteria,2GNX6@201174|Actinobacteria	201174|Actinobacteria	F	CYTH domain	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
DEZH2_k127_565827_57	754035.Mesau_00133	1.188e-34	136.0	COG0346@1|root,COG0346@2|Bacteria,1RHQB@1224|Proteobacteria,2UDWR@28211|Alphaproteobacteria,43M24@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DEZH2_k127_565827_6	479431.Namu_2466	2.923e-128	412.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria,4EV2S@85013|Frankiales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DEZH2_k127_565827_7	78346.BRUM_1353	2.44e-121	406.0	COG0507@1|root,COG0507@2|Bacteria,2HFY1@201174|Actinobacteria,4CZ0C@85004|Bifidobacteriales	201174|Actinobacteria	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	PIF1
DEZH2_k127_565827_59	1151122.AQYD01000007_gene1565	4.112e-33	132.0	2DS51@1|root,33EJB@2|Bacteria,2IM77@201174|Actinobacteria,4FPD7@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
DEZH2_k127_565827_47	935840.JAEQ01000016_gene2152	5.495e-46	177.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2TUV9@28211|Alphaproteobacteria,43KVJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
DEZH2_k127_565827_13	911104.AEKT01000015_gene378	8.064e-106	357.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HF0E@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
DEZH2_k127_565827_23	331113.SNE_A17470	9.587e-80	277.0	COG0391@1|root,COG0391@2|Bacteria	2|Bacteria	S	phosphotransferase activity, for other substituted phosphate groups	ybhK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
DEZH2_k127_565827_55	574966.KB898646_gene2892	1.176e-36	149.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1XIYJ@135619|Oceanospirillales	135619|Oceanospirillales	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DEZH2_k127_565827_86	1235798.C817_01803	1.698e-13	76.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,27VIS@189330|Dorea	186801|Clostridia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
DEZH2_k127_565827_30	1173024.KI912148_gene3640	3.928e-63	228.0	COG0275@1|root,COG0275@2|Bacteria,1G0AR@1117|Cyanobacteria,1JHJ4@1189|Stigonemataceae	1117|Cyanobacteria	M	MraW methylase family	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
DEZH2_k127_565827_24	525904.Tter_1614	1.266e-77	282.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
DEZH2_k127_565827_33	309801.trd_0060	7.441e-62	226.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
DEZH2_k127_565827_35	1121428.DESHY_50032___1	1.674e-60	226.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DEZH2_k127_565827_43	760011.Spico_0638	4.446e-49	190.0	COG0707@1|root,COG0707@2|Bacteria,2J5XF@203691|Spirochaetes	203691|Spirochaetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DEZH2_k127_565827_8	1047013.AQSP01000118_gene1252	1.216e-120	421.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_565827_96	1280941.HY2_11780	1.079e-07	63.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,43WH3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Ank,Sigma70_r2,Sigma70_r3,Sigma70_r4
DEZH2_k127_565827_1	1124780.ANNU01000002_gene1575	6.765e-248	786.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
DEZH2_k127_565827_41	1158318.ATXC01000001_gene669	1.593e-54	201.0	COG0758@1|root,COG0758@2|Bacteria,2G3ZI@200783|Aquificae	200783|Aquificae	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
DEZH2_k127_565827_52	1408415.JHXL01000008_gene167	4.226e-38	150.0	COG0193@1|root,COG0193@2|Bacteria,3WT8R@544448|Tenericutes	544448|Tenericutes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DEZH2_k127_565827_16	324602.Caur_3106	1.562e-94	327.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,375A1@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
DEZH2_k127_565827_51	653733.Selin_1531	2.896e-40	158.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DEZH2_k127_6091941_1	1242864.D187_005418	7.789e-22	98.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria	1224|Proteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
DEZH2_k127_6091941_0	261292.Nit79A3_1646	7.845e-95	323.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,2VMZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
DEZH2_k127_6361187_45	1265313.HRUBRA_00572	7.51e-12	70.0	COG0431@1|root,COG0431@2|Bacteria,1RBNR@1224|Proteobacteria,1T04G@1236|Gammaproteobacteria,1J9FD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DEZH2_k127_6361187_24	1198232.CYCME_2365	9.682e-43	169.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,1RRYS@1236|Gammaproteobacteria,4624P@72273|Thiotrichales	72273|Thiotrichales	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
DEZH2_k127_6361187_29	136037.KDR21201	8.392e-31	127.0	COG0225@1|root,KOG1635@2759|Eukaryota,39U04@33154|Opisthokonta,3BC3C@33208|Metazoa,3CZ0C@33213|Bilateria,41XWW@6656|Arthropoda,3SKYJ@50557|Insecta	33208|Metazoa	O	Peptide methionine sulfoxide	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DEZH2_k127_6361187_47	869210.Marky_1650	3.639e-09	67.0	COG0580@1|root,COG0580@2|Bacteria,1WKA2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DEZH2_k127_6361187_23	1047013.AQSP01000140_gene2513	7.47e-44	175.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
DEZH2_k127_6361187_48	1340434.AXVA01000007_gene5137	2.73e-07	58.0	COG0671@1|root,COG0671@2|Bacteria,1UZ1A@1239|Firmicutes,4HDCB@91061|Bacilli,1ZFNG@1386|Bacillus	91061|Bacilli	I	Bacitracin ABC transporter permease	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DEZH2_k127_6361187_12	656024.FsymDg_3812	2.346e-78	274.0	COG2899@1|root,COG2899@2|Bacteria,2GJNH@201174|Actinobacteria,4ES65@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
DEZH2_k127_6361187_8	867902.Ornrh_1375	1.74e-98	336.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DEZH2_k127_6361187_22	1206732.BAGD01000083_gene3590	3.264e-44	177.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4FWNU@85025|Nocardiaceae	201174|Actinobacteria	I	Prolyl oligopeptidase family	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
DEZH2_k127_6361187_17	1449048.JQKU01000020_gene479	1.431e-54	196.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,238S4@1762|Mycobacteriaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
DEZH2_k127_6361187_28	35754.JNYJ01000006_gene5263	3.485e-32	129.0	COG0346@1|root,COG0346@2|Bacteria,2GSEN@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DEZH2_k127_6361187_25	1001240.GY21_20375	7.295e-40	149.0	2E5NA@1|root,330D3@2|Bacteria,2IQ91@201174|Actinobacteria,4FPKE@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
DEZH2_k127_6361187_10	369723.Strop_2927	3.606e-86	292.0	COG3022@1|root,COG3022@2|Bacteria	2|Bacteria	S	response to hydroperoxide	yaaA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
DEZH2_k127_6361187_51	110662.Syncc9605_0872	4.788e-06	57.0	COG0681@1|root,COG0681@2|Bacteria,1GA6F@1117|Cyanobacteria,1H1GX@1129|Synechococcus	1117|Cyanobacteria	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
DEZH2_k127_6361187_37	1128427.KB904821_gene1037	6.818e-24	106.0	293MU@1|root,2ZR3M@2|Bacteria,1G5DA@1117|Cyanobacteria,1HAY6@1150|Oscillatoriales	1117|Cyanobacteria	S	Nickel-containing superoxide dismutase	sodN	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
DEZH2_k127_6361187_15	1122927.KB895418_gene2644	2.12e-73	252.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26RCU@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DEZH2_k127_6361187_42	717231.Flexsi_1964	5.23e-14	77.0	COG1837@1|root,COG1837@2|Bacteria,2GFZI@200930|Deferribacteres	200930|Deferribacteres	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
DEZH2_k127_6361187_46	519441.Smon_1447	1.607e-10	66.0	COG0228@1|root,COG0228@2|Bacteria,37AM9@32066|Fusobacteria	32066|Fusobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
DEZH2_k127_6361187_20	411490.ANACAC_00339	4.323e-48	181.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DEZH2_k127_6361187_39	383372.Rcas_0433	2.388e-16	85.0	COG1051@1|root,COG1051@2|Bacteria,2GBN0@200795|Chloroflexi,3782V@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DEZH2_k127_6361187_31	485913.Krac_8246	3.765e-27	116.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DEZH2_k127_6361187_0	573413.Spirs_0283	1.362e-290	912.0	COG0495@1|root,COG0495@2|Bacteria,2J5BV@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
DEZH2_k127_6361187_19	1278073.MYSTI_04345	3.125e-48	183.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_6361187_30	1278073.MYSTI_04345	2.894e-30	124.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_6361187_11	367299.JOEE01000001_gene2003	1.867e-82	281.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4FF6C@85021|Intrasporangiaceae	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DEZH2_k127_6361187_13	1394178.AWOO02000038_gene9061	9.836e-75	260.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4EITI@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DEZH2_k127_6361187_32	1033732.CAHI01000009_gene1637	4.898e-26	111.0	COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,2G2C1@200643|Bacteroidia	976|Bacteroidetes	S	RNA recognition motif	ykfA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DEZH2_k127_6361187_1	452863.Achl_2586	4.797e-213	677.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,1WBE0@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
DEZH2_k127_6361187_2	266264.Rmet_1428	7.143e-163	535.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1K0GW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DEZH2_k127_6361187_6	1001240.GY21_02600	1.536e-113	372.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4FMKM@85023|Microbacteriaceae	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
DEZH2_k127_6361187_14	1121924.ATWH01000013_gene540	1.097e-73	252.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4FK45@85023|Microbacteriaceae	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DEZH2_k127_6361187_16	574375.BAGA_16105	9.774e-55	198.0	COG2141@1|root,COG2141@2|Bacteria,1VDI6@1239|Firmicutes,4HMYV@91061|Bacilli	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6361187_26	1122179.KB890443_gene1207	8.896e-39	150.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,1ITGH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DEZH2_k127_6361187_43	1122222.AXWR01000002_gene2083	9.054e-13	71.0	COG0607@1|root,COG0607@2|Bacteria,1WJ03@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DEZH2_k127_6361187_44	67257.JODR01000027_gene2832	3.405e-12	71.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	furA	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DEZH2_k127_6361187_40	1144307.PMI04_04280	1.395e-15	86.0	COG1073@1|root,COG1073@2|Bacteria,1NXZW@1224|Proteobacteria,2TSEE@28211|Alphaproteobacteria,2K8XI@204457|Sphingomonadales	204457|Sphingomonadales	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
DEZH2_k127_6361187_36	324602.Caur_3359	3.852e-25	111.0	2EBNS@1|root,335NZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6361187_38	582515.KR51_00023560	1.508e-22	104.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DEZH2_k127_6361187_18	2045.KR76_03495	5.401e-52	190.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4DPBH@85009|Propionibacteriales	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DEZH2_k127_6361187_27	101510.RHA1_ro00580	5.32e-33	130.0	COG4430@1|root,COG4430@2|Bacteria,2IQK3@201174|Actinobacteria,4G7QZ@85025|Nocardiaceae	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
DEZH2_k127_6361187_41	266809.PM03_14020	2.126e-14	81.0	2CCI4@1|root,30BPJ@2|Bacteria,1RE42@1224|Proteobacteria,2U92A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6361187_35	521011.Mpal_1494	1.023e-25	111.0	COG5507@1|root,arCOG09468@2157|Archaea,2Y13Q@28890|Euryarchaeota,2NB85@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
DEZH2_k127_6361187_50	1123248.KB893319_gene4004	1.627e-06	52.0	2BZQY@1|root,2ZVH4@2|Bacteria,4P73I@976|Bacteroidetes,1IZGJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6361187_21	1033734.CAET01000002_gene4425	3.508e-47	171.0	COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HIP5@91061|Bacilli,1ZGCP@1386|Bacillus	91061|Bacilli	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
DEZH2_k127_6361187_33	1123405.AUMM01000017_gene2671	8.415e-26	109.0	COG4817@1|root,COG4817@2|Bacteria,1V94R@1239|Firmicutes,4HJP0@91061|Bacilli,26Q4W@186821|Sporolactobacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1048)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1048
DEZH2_k127_6361187_4	431943.CKL_3534	3.884e-115	376.0	COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,248R4@186801|Clostridia,36VFG@31979|Clostridiaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DEZH2_k127_6361187_3	169963.lmo0980	1.096e-120	391.0	COG0842@1|root,COG0842@2|Bacteria,1TS7U@1239|Firmicutes,4HA36@91061|Bacilli,26KE8@186820|Listeriaceae	91061|Bacilli	V	Transport permease protein	drrB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DEZH2_k127_6361187_34	547163.BN979_05253	9.526e-26	110.0	COG5646@1|root,COG5646@2|Bacteria,2HRJZ@201174|Actinobacteria,23C0N@1762|Mycobacteriaceae	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DEZH2_k127_6361187_7	575590.HMPREF0156_01408	1.518e-109	359.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DEZH2_k127_6361187_9	1225785.CM001983_gene684	3e-95	322.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,2JCI1@204037|Dickeya	1236|Gammaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477	Dala_Dala_lig_C,Dala_Dala_lig_N
DEZH2_k127_6361187_5	945713.IALB_0734	1.491e-114	381.0	COG2256@1|root,COG2256@2|Bacteria	2|Bacteria	L	atpase related to the helicase subunit of the holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DEZH2_k127_6447395_1	1192759.AKIB01000104_gene3353	3.323e-49	176.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,2K539@204457|Sphingomonadales	204457|Sphingomonadales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DEZH2_k127_6447395_0	1248760.ANFZ01000009_gene1223	1.069e-214	669.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2K0H3@204457|Sphingomonadales	204457|Sphingomonadales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DEZH2_k127_6687468_0	1125779.HMPREF1219_01102	6.448e-85	292.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria,22JPR@1653|Corynebacteriaceae	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease components	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DEZH2_k127_6782600_0	716544.wcw_p0013	2.389e-07	62.0	COG3378@1|root,COG3378@2|Bacteria,2JH8Z@204428|Chlamydiae	204428|Chlamydiae	S	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N
DEZH2_k127_6901288_57	590998.Celf_2226	1.421e-26	116.0	COG2314@1|root,COG2314@2|Bacteria,2HFAJ@201174|Actinobacteria,4F2Z9@85016|Cellulomonadaceae	2|Bacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp,TM2
DEZH2_k127_6901288_99	926556.Echvi_1037	0.0005146	47.0	2E3MC@1|root,32YJJ@2|Bacteria,4NWQZ@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
DEZH2_k127_6901288_22	1410658.JHWI01000015_gene1683	4.02e-90	308.0	COG0812@1|root,COG0812@2|Bacteria,1UY20@1239|Firmicutes,3VT79@526524|Erysipelotrichia	526524|Erysipelotrichia	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C
DEZH2_k127_6901288_4	526222.Desal_1305	1.897e-155	501.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2M9J9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DEZH2_k127_6901288_1	1385519.N801_01495	1.651e-224	706.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4FEVM@85021|Intrasporangiaceae	201174|Actinobacteria	M	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
DEZH2_k127_6901288_97	555088.DealDRAFT_0032	0.0003533	51.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
DEZH2_k127_6901288_47	6326.BUX.s00351.108	9.096e-34	139.0	COG0127@1|root,KOG3222@2759|Eukaryota,38DZ3@33154|Opisthokonta,3BE5N@33208|Metazoa,3CSAU@33213|Bilateria,40DDE@6231|Nematoda,1KVR4@119089|Chromadorea	33208|Metazoa	F	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions	ITPA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006193,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009150,GO:0009154,GO:0009166,GO:0009199,GO:0009203,GO:0009205,GO:0009207,GO:0009259,GO:0009261,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046041,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0051276,GO:0055086,GO:0071704,GO:0071840,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K01519	ko00230,ko00983,ko01100,map00230,map00983,map01100	-	R00426,R00720,R01855,R02100,R02720,R03531,R08243	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DEZH2_k127_6901288_18	648996.Theam_1071	1.776e-100	358.0	COG0542@1|root,COG0542@2|Bacteria,2G3N7@200783|Aquificae	200783|Aquificae	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DEZH2_k127_6901288_6	1312954.KI914860_gene878	1.454e-150	490.0	COG0770@1|root,COG0770@2|Bacteria,2I2EU@201174|Actinobacteria,1W7KI@1268|Micrococcaceae	201174|Actinobacteria	M	Mur ligase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
DEZH2_k127_6901288_23	1312954.KI914860_gene877	4.051e-90	302.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,1W7IS@1268|Micrococcaceae	201174|Actinobacteria	S	glutamine amidotransferase	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
DEZH2_k127_6901288_24	585530.HMPREF0183_2401	8.433e-89	306.0	COG4645@1|root,COG4645@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OpgC_C
DEZH2_k127_6901288_49	1194165.CAJF01000026_gene3344	1.113e-31	129.0	COG0526@1|root,COG0526@2|Bacteria,2GRCM@201174|Actinobacteria,4FSME@85023|Microbacteriaceae	201174|Actinobacteria	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
DEZH2_k127_6901288_27	1348338.ADILRU_0707	3.551e-78	268.0	COG0785@1|root,COG0785@2|Bacteria,2IK3K@201174|Actinobacteria,4FR0J@85023|Microbacteriaceae	201174|Actinobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
DEZH2_k127_6901288_38	1122223.KB890696_gene210	9.711e-46	172.0	COG1225@1|root,COG1225@2|Bacteria,1WI9E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DEZH2_k127_6901288_8	246194.CHY_1168	2.203e-142	467.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,42F5Q@68295|Thermoanaerobacterales	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DEZH2_k127_6901288_60	477641.MODMU_4182	1.499e-23	113.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4EVVV@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
DEZH2_k127_6901288_54	1210884.HG799465_gene11380	5.898e-30	136.0	COG3209@1|root,COG3210@1|root,COG4625@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
DEZH2_k127_6901288_82	255470.cbdbA344	3.268e-10	66.0	COG0637@1|root,COG1214@1|root,COG0637@2|Bacteria,COG1214@2|Bacteria,2G6ZZ@200795|Chloroflexi,34D2B@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Glycoprotease family	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Peptidase_M22
DEZH2_k127_6901288_66	1219626.HMPREF1639_05100	3.026e-19	93.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,25RB4@186804|Peptostreptococcaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DEZH2_k127_6901288_10	639282.DEFDS_1109	2.082e-134	448.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
DEZH2_k127_6901288_26	42256.RradSPS_0863	9.241e-81	283.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DEZH2_k127_6901288_88	187272.Mlg_2391	1.531e-06	56.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1WY8U@135613|Chromatiales	135613|Chromatiales	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
DEZH2_k127_6901288_62	1249627.D779_0848	1.374e-22	109.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DEZH2_k127_6901288_87	264732.Moth_0077	4.817e-07	59.0	COG3881@1|root,COG3881@2|Bacteria,1V29A@1239|Firmicutes,24GY0@186801|Clostridia,42H1E@68295|Thermoanaerobacterales	186801|Clostridia	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
DEZH2_k127_6901288_67	479434.Sthe_1432	4.457e-17	89.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,27YM4@189775|Thermomicrobia	189775|Thermomicrobia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
DEZH2_k127_6901288_7	357809.Cphy_2439	1.368e-146	473.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,21XNP@1506553|Lachnoclostridium	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DEZH2_k127_6901288_11	1304880.JAGB01000002_gene1856	3.89e-133	432.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
DEZH2_k127_6901288_51	1280679.ATVX01000010_gene2320	1.528e-31	130.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,4BYC9@830|Butyrivibrio	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DEZH2_k127_6901288_92	448385.sce5470	2.898e-05	55.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce5470|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6901288_36	1007103.AFHW01000098_gene5111	1.257e-50	186.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,4HGM3@91061|Bacilli,26SYI@186822|Paenibacillaceae	91061|Bacilli	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DEZH2_k127_6901288_100	1370120.AUWR01000056_gene2965	0.0005654	52.0	2BFPV@1|root,31WD7@2|Bacteria,2GX22@201174|Actinobacteria,23BSN@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6901288_30	929712.KI912613_gene3513	8.044e-65	229.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CPAM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DEZH2_k127_6901288_74	526226.Gbro_3188	7.76e-15	87.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4GBBI@85026|Gordoniaceae	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
DEZH2_k127_6901288_33	292564.Cyagr_0851	1.409e-56	207.0	COG0524@1|root,COG0524@2|Bacteria,1GBJ2@1117|Cyanobacteria,22THP@167375|Cyanobium	1117|Cyanobacteria	G	pfkB family carbohydrate kinase	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DEZH2_k127_6901288_17	312309.VF_0658	1.955e-101	338.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XT40@135623|Vibrionales	135623|Vibrionales	F	Belongs to the RimK family	rimK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
DEZH2_k127_6901288_68	504472.Slin_6088	5.141e-17	86.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
DEZH2_k127_6901288_41	1356854.N007_00185	2.601e-43	171.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1V3WY@1239|Firmicutes,4HHHK@91061|Bacilli,277V8@186823|Alicyclobacillaceae	91061|Bacilli	HJM	RimK-like ATP-grasp domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	ATP-grasp_3,Mur_ligase_C,Mur_ligase_M,RimK
DEZH2_k127_6901288_72	680646.RMDY18_04710	1.914e-15	91.0	COG3827@1|root,COG3827@2|Bacteria,2GZEG@201174|Actinobacteria,1WBT3@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6901288_15	545243.BAEV01000090_gene2265	1.126e-102	346.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,36E5A@31979|Clostridiaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DEZH2_k127_6901288_95	873448.STRPO_1874	0.0001225	49.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,4HIP6@91061|Bacilli	91061|Bacilli	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DEZH2_k127_6901288_0	1121396.KB893125_gene4538	1.536e-242	764.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MJ2X@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DEZH2_k127_6901288_77	1298867.AUES01000001_gene1773	1.953e-13	83.0	2A0ZP@1|root,30P52@2|Bacteria,1PDZ1@1224|Proteobacteria,2U0VG@28211|Alphaproteobacteria,3JUTT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	MA20_34770	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6901288_56	525904.Tter_0120	1.071e-27	121.0	COG1670@1|root,COG1670@2|Bacteria,2NPXX@2323|unclassified Bacteria	2|Bacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DEZH2_k127_6901288_59	904296.HMPREF9124_1095	6.793e-26	114.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,2PS8W@265975|Oribacterium	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DEZH2_k127_6901288_61	1321775.HMPREF1980_01608	5.7e-23	107.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4D3H3@85005|Actinomycetales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
DEZH2_k127_6901288_55	795797.C497_04105	3.445e-28	121.0	COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,23SWN@183963|Halobacteria	183963|Halobacteria	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DEZH2_k127_6901288_2	1469613.JT55_12615	4.369e-200	639.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,3FCGZ@34008|Rhodovulum	28211|Alphaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
DEZH2_k127_6901288_34	479434.Sthe_1218	8.398e-53	206.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
DEZH2_k127_6901288_3	926550.CLDAP_02810	6.347e-175	567.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
DEZH2_k127_6901288_46	1121011.AUCB01000002_gene525	1.123e-34	144.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1HYBN@117743|Flavobacteriia,23GY2@178469|Arenibacter	976|Bacteroidetes	D	PP-loop family	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
DEZH2_k127_6901288_86	293826.Amet_4326	4.301e-07	54.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia,36N2I@31979|Clostridiaceae	186801|Clostridia	O	glutaredoxin-like protein, YruB-family	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DEZH2_k127_6901288_5	1348662.CARG_03170	8.115e-153	501.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,2GKDT@201174|Actinobacteria,22KBX@1653|Corynebacteriaceae	201174|Actinobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dipZ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
DEZH2_k127_6901288_40	1429851.X548_10050	2.579e-43	166.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,1X6JY@135614|Xanthomonadales	135614|Xanthomonadales	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
DEZH2_k127_6901288_89	1366050.N234_03070	2.491e-06	55.0	COG1846@1|root,COG1846@2|Bacteria,1N2K6@1224|Proteobacteria,2VTAJ@28216|Betaproteobacteria,1K8AC@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
DEZH2_k127_6901288_44	235909.GK0330	8.636e-37	152.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,4ISRX@91061|Bacilli,1WEZJ@129337|Geobacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DEZH2_k127_6901288_28	1499967.BAYZ01000055_gene4856	2.739e-67	237.0	COG0745@1|root,COG0745@2|Bacteria,2NP9R@2323|unclassified Bacteria	2|Bacteria	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_6901288_12	1122939.ATUD01000007_gene2104	1.643e-126	421.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CR7R@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DEZH2_k127_6901288_75	1463917.JODC01000008_gene3195	1.023e-14	79.0	COG1846@1|root,COG1846@2|Bacteria,2IFRN@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
DEZH2_k127_6901288_69	1366046.HIMB11_00357	7.707e-17	91.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VGB7@28211|Alphaproteobacteria,3ZHBD@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	G3E family	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
DEZH2_k127_6901288_52	408672.NBCG_00429	1.891e-31	133.0	COG1063@1|root,COG1063@2|Bacteria,2GPPT@201174|Actinobacteria	201174|Actinobacteria	E	Nicotianamine synthase protein	-	-	-	-	-	-	-	-	-	-	-	-	NAS
DEZH2_k127_6901288_70	373903.Hore_05900	4.177e-16	84.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,24JQE@186801|Clostridia,3WAUX@53433|Halanaerobiales	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DEZH2_k127_6901288_25	237368.SCABRO_01822	7.436e-86	301.0	COG1249@1|root,COG1249@2|Bacteria,2IYD2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
DEZH2_k127_6901288_48	1121020.JIAG01000004_gene1965	1.205e-32	132.0	COG0237@1|root,COG0237@2|Bacteria,2I7JH@201174|Actinobacteria	201174|Actinobacteria	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6901288_79	1521187.JPIM01000125_gene3589	5.93e-11	68.0	COG3544@1|root,COG3544@2|Bacteria,2G95K@200795|Chloroflexi,375UR@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
DEZH2_k127_6901288_58	219305.MCAG_03353	6.704e-26	110.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4DE7U@85008|Micromonosporales	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
DEZH2_k127_6901288_31	1385520.N802_03955	2.697e-64	224.0	297W1@1|root,2ZV2M@2|Bacteria,2II0V@201174|Actinobacteria,4FGX0@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
DEZH2_k127_6901288_50	883078.HMPREF9695_03832	1.122e-31	134.0	2E54J@1|root,32ZXH@2|Bacteria,1R9DG@1224|Proteobacteria,2U2YG@28211|Alphaproteobacteria,3JR4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6901288_71	171693.BN988_02403	9.987e-16	85.0	COG0546@1|root,COG0546@2|Bacteria,1V1K2@1239|Firmicutes,4HGEI@91061|Bacilli,23KHI@182709|Oceanobacillus	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
DEZH2_k127_6901288_96	370438.PTH_0188	0.0002204	49.0	COG2919@1|root,COG2919@2|Bacteria,1VGDD@1239|Firmicutes,25PD5@186801|Clostridia,26308@186807|Peptococcaceae	186801|Clostridia	D	PFAM Septum formation initiator	-	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
DEZH2_k127_6901288_78	1487923.DP73_13985	2.853e-11	69.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia,265M7@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
DEZH2_k127_6901288_21	1227261.HMPREF0043_01904	9.654e-93	317.0	COG0842@1|root,COG0842@2|Bacteria,2IB08@201174|Actinobacteria,4D4NV@85005|Actinomycetales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
DEZH2_k127_6901288_19	1227261.HMPREF0043_01903	6.341e-97	323.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4D63Y@85005|Actinomycetales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DEZH2_k127_6901288_80	1047013.AQSP01000066_gene724	1.164e-10	64.0	2E5PY@1|root,330EK@2|Bacteria,2NS29@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6901288_94	888064.HMPREF9088_0380	7.455e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,4AZ9K@81852|Enterococcaceae	91061|Bacilli	EGP	MFS_1 like family	pmrB	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,Sugar_tr
DEZH2_k127_6901288_14	1408321.JNJD01000012_gene2287	6.018e-115	384.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,27IH7@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_6901288_45	926549.KI421517_gene3494	2.387e-35	142.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,47JY6@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
DEZH2_k127_6901288_63	436114.SYO3AOP1_0956	3.318e-21	100.0	COG0009@1|root,COG0009@2|Bacteria,2G48I@200783|Aquificae	200783|Aquificae	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
DEZH2_k127_6901288_32	1189620.AJXL01000097_gene2050	2.38e-58	213.0	COG0668@1|root,COG0668@2|Bacteria,4NH7C@976|Bacteroidetes,1ICX5@117743|Flavobacteriia,2NVTM@237|Flavobacterium	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
DEZH2_k127_6901288_29	880072.Desac_0324	4.723e-67	237.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2MQVX@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM HhH-GPD superfamily base excision DNA repair protein	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DEZH2_k127_6901288_83	196627.cg0549	9.142e-10	63.0	COG2154@1|root,COG2154@2|Bacteria,2HP24@201174|Actinobacteria,22PCZ@1653|Corynebacteriaceae	201174|Actinobacteria	H	COG2154 Pterin-4a-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DEZH2_k127_6901288_37	1191523.MROS_0740	1.214e-47	179.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	tag	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
DEZH2_k127_6901288_35	1122237.AUGQ01000001_gene1030	9.868e-51	187.0	COG2220@1|root,COG2220@2|Bacteria,2GNHK@201174|Actinobacteria,4FN27@85023|Microbacteriaceae	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
DEZH2_k127_6901288_73	1444310.JANV01000144_gene365	2.812e-15	83.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,1ZDQW@1386|Bacillus	91061|Bacilli	G	Belongs to the phosphoglycerate mutase family	yhfR	-	5.4.2.12	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
DEZH2_k127_6901288_20	649638.Trad_2070	1.271e-94	325.0	COG0017@1|root,COG0017@2|Bacteria,1WJAX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspC	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DEZH2_k127_6901288_64	1121439.dsat_1056	1.323e-20	103.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2WKUD@28221|Deltaproteobacteria,2M8FS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
DEZH2_k127_6901288_43	445961.IW15_21995	1.864e-37	150.0	COG1651@1|root,COG1651@2|Bacteria,4NQ9P@976|Bacteroidetes,1I8YG@117743|Flavobacteriia,3ZPI2@59732|Chryseobacterium	976|Bacteroidetes	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
DEZH2_k127_6901288_42	1121335.Clst_0022	9.864e-39	157.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,3WGVT@541000|Ruminococcaceae	186801|Clostridia	P	Mg2 transporter protein CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DEZH2_k127_6901288_13	406327.Mevan_1221	8.088e-118	398.0	COG0475@1|root,arCOG01955@2157|Archaea,2XWIX@28890|Euryarchaeota,23RH1@183939|Methanococci	183939|Methanococci	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
DEZH2_k127_6901288_16	401526.TcarDRAFT_1800	1.515e-102	362.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DEZH2_k127_6901288_84	384616.Pisl_0088	5.67e-09	62.0	COG0494@1|root,arCOG01078@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DEZH2_k127_6901288_76	340099.Teth39_0964	1.777e-13	79.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,42FXF@68295|Thermoanaerobacterales	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DEZH2_k127_6901288_39	1112204.GPOL_c18810	2.59e-44	167.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
DEZH2_k127_6901288_53	929703.KE386491_gene3108	2.156e-31	126.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,47R0R@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DEZH2_k127_6901288_9	240302.BN982_01195	4.739e-135	436.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3NFYG@45667|Halobacillus	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
DEZH2_k127_6901288_65	287986.DV20_05535	1.361e-20	96.0	COG2246@1|root,COG2246@2|Bacteria,2GUYY@201174|Actinobacteria,4E70M@85010|Pseudonocardiales	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
DEZH2_k127_6901288_81	240015.ACP_0231	2.188e-10	67.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria,2JIJ3@204432|Acidobacteriia	204432|Acidobacteriia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
DEZH2_k127_6901288_90	632335.Calkr_0332	2.086e-05	53.0	COG2246@1|root,COG2246@2|Bacteria,1VFGI@1239|Firmicutes,24RJP@186801|Clostridia,42H4K@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM GtrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
DEZH2_k127_6901288_101	1304872.JAGC01000009_gene337	0.0009402	51.0	2AHDZ@1|root,317R1@2|Bacteria,1PZ3P@1224|Proteobacteria,435PJ@68525|delta/epsilon subdivisions,2X03E@28221|Deltaproteobacteria,2MA9H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DEZH2_k127_707202_0	159749.K0TJ16	1.107e-108	367.0	COG2801@1|root,KOG0017@2759|Eukaryota	159749.K0TJ16|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7105156_0	109760.SPPG_08009T0	5.688e-11	68.0	COG5262@1|root,KOG1756@2759|Eukaryota,3A1K0@33154|Opisthokonta,3P2TD@4751|Fungi	4751|Fungi	B	Histone H2a	HTA1	GO:0000070,GO:0000122,GO:0000228,GO:0000278,GO:0000280,GO:0000775,GO:0000781,GO:0000784,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0000792,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005694,GO:0005720,GO:0005721,GO:0005724,GO:0006139,GO:0006259,GO:0006281,GO:0006282,GO:0006323,GO:0006325,GO:0006333,GO:0006342,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007076,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010604,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0019219,GO:0019222,GO:0022402,GO:0030261,GO:0031298,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031618,GO:0031933,GO:0031934,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0033036,GO:0033365,GO:0033553,GO:0033554,GO:0034501,GO:0034502,GO:0034613,GO:0034641,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0045739,GO:0045814,GO:0045892,GO:0045934,GO:0045935,GO:0046483,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051252,GO:0051253,GO:0051276,GO:0051641,GO:0051716,GO:0060255,GO:0061587,GO:0065007,GO:0070013,GO:0070727,GO:0071103,GO:0071459,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0098687,GO:0098813,GO:0140014,GO:1901360,GO:1901363,GO:1902377,GO:1902679,GO:1903047,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001020,GO:2001022,GO:2001141	-	ko:K11251	ko04217,ko05034,ko05322,map04217,map05034,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone,Histone_H2A_C
DEZH2_k127_7464527_0	744872.Spica_2869	1.777e-118	385.0	COG0187@1|root,COG0187@2|Bacteria,2J67M@203691|Spirochaetes	203691|Spirochaetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DEZH2_k127_7666303_35	470145.BACCOP_04319	7.301e-60	209.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,2FNC2@200643|Bacteroidia,4AMGS@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score	wcaJ_2	-	2.7.8.6	ko:K00996,ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
DEZH2_k127_7666303_21	635013.TherJR_2842	5.473e-84	291.0	COG0438@1|root,COG0438@2|Bacteria,1TQN3@1239|Firmicutes,24ARN@186801|Clostridia,260IV@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DEZH2_k127_7666303_2	290317.Cpha266_2676	1.574e-178	577.0	COG0449@1|root,COG0449@2|Bacteria,1FDCR@1090|Chlorobi	1090|Chlorobi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DEZH2_k127_7666303_37	642492.Clole_3817	2.44e-58	215.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia	186801|Clostridia	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
DEZH2_k127_7666303_32	1120960.ATXG01000010_gene2655	9.884e-63	240.0	COG0739@1|root,COG5479@1|root,COG5640@1|root,COG0739@2|Bacteria,COG5479@2|Bacteria,COG5640@2|Bacteria,2HYIN@201174|Actinobacteria,4FMC4@85023|Microbacteriaceae	201174|Actinobacteria	M	hydrolase, family 25	wcqK	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LGFP,SH3_3
DEZH2_k127_7666303_109	765420.OSCT_1282	0.0004399	53.0	COG1287@1|root,COG1287@2|Bacteria,2GAA0@200795|Chloroflexi,376PD@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_102	1380390.JIAT01000009_gene2222	2.567e-05	56.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	Polysacc_synt,Polysacc_synt_3
DEZH2_k127_7666303_31	1321815.HMPREF9193_00701	1.499e-65	235.0	COG0463@1|root,COG0463@2|Bacteria,2J7NM@203691|Spirochaetes	203691|Spirochaetes	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K20534	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
DEZH2_k127_7666303_33	1449976.KALB_156	1.653e-60	223.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4E1Y6@85010|Pseudonocardiales	201174|Actinobacteria	G	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DEZH2_k127_7666303_49	272134.KB731324_gene4493	1.361e-42	168.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_11,Methyltransf_23
DEZH2_k127_7666303_43	466088.CL42_04525	1.378e-52	201.0	COG0438@1|root,COG0438@2|Bacteria,1RGME@1224|Proteobacteria,1SZ9U@1236|Gammaproteobacteria,3NT2H@468|Moraxellaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DEZH2_k127_7666303_9	1048339.KB913029_gene4416	3.262e-141	477.0	COG0438@1|root,COG0500@1|root,COG0438@2|Bacteria,COG2226@2|Bacteria,2GKX4@201174|Actinobacteria,4EU30@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DEZH2_k127_7666303_39	1172190.M947_11335	5.75e-57	213.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2YNE2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DEZH2_k127_7666303_29	1048339.KB913029_gene4417	2.355e-66	236.0	COG1196@1|root,COG1196@2|Bacteria,2HVYZ@201174|Actinobacteria,4EW9J@85013|Frankiales	201174|Actinobacteria	D	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DEZH2_k127_7666303_55	551115.Aazo_5202	4.902e-33	141.0	COG2227@1|root,COG4122@1|root,COG2227@2|Bacteria,COG4122@2|Bacteria,1GCG8@1117|Cyanobacteria,1HQ16@1161|Nostocales	1117|Cyanobacteria	H	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_21
DEZH2_k127_7666303_18	1437608.BBIA_0036	9.778e-100	339.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4CZ1B@85004|Bifidobacteriales	201174|Actinobacteria	GM	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Wzt_C
DEZH2_k127_7666303_23	1158606.I579_01776	3.448e-76	266.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,4IPZZ@91061|Bacilli	91061|Bacilli	GM	Transport permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
DEZH2_k127_7666303_25	1048339.KB913029_gene4418	4.162e-72	254.0	COG0451@1|root,COG0451@2|Bacteria,2I4MR@201174|Actinobacteria	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	gca	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DEZH2_k127_7666303_61	553174.HMPREF0659_A5812	6.942e-27	116.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,2FRB2@200643|Bacteroidia	976|Bacteroidetes	L	Hydrolase, NUDIX family	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
DEZH2_k127_7666303_5	1048339.KB913029_gene4419	2.023e-167	532.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria,4ERDN@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DEZH2_k127_7666303_50	1218103.CIN01S_04_02980	4.805e-40	155.0	COG0662@1|root,COG0662@2|Bacteria,4NNWT@976|Bacteroidetes,1I25A@117743|Flavobacteriia,3ZQZE@59732|Chryseobacterium	976|Bacteroidetes	G	Phosphoheptose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
DEZH2_k127_7666303_51	1499967.BAYZ01000026_gene1589	6.051e-38	156.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DEZH2_k127_7666303_73	1463841.JOIR01000002_gene6009	1.312e-15	92.0	COG0741@1|root,COG0741@2|Bacteria,2IHFV@201174|Actinobacteria	201174|Actinobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DEZH2_k127_7666303_62	316067.Geob_1139	8.127e-24	109.0	COG0593@1|root,COG1943@1|root,COG0593@2|Bacteria,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RDM@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Chromosomal replication initiator, DnaA	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Bac_DnaA_C,Y1_Tnp
DEZH2_k127_7666303_70	332101.JIBU02000034_gene1854	6.191e-17	88.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,36F11@31979|Clostridiaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
DEZH2_k127_7666303_69	755731.Clo1100_4115	2.948e-17	93.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,36FE7@31979|Clostridiaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
DEZH2_k127_7666303_107	321327.CYA_2904	0.000119	49.0	COG0594@1|root,COG0594@2|Bacteria,1GP6I@1117|Cyanobacteria,1H2C8@1129|Synechococcus	1117|Cyanobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DEZH2_k127_7666303_84	883113.HMPREF9708_00689	5.26e-11	64.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,27E8I@186827|Aerococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DEZH2_k127_7666303_14	479434.Sthe_0001	6.153e-116	389.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,27XP6@189775|Thermomicrobia	189775|Thermomicrobia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DEZH2_k127_7666303_30	552811.Dehly_0949	3.818e-66	241.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,34CUN@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DEZH2_k127_7666303_45	1321784.HMPREF1987_00067	1.51e-51	196.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
DEZH2_k127_7666303_81	1510531.JQJJ01000011_gene2894	1.24e-12	80.0	COG5283@1|root,COG5283@2|Bacteria,1NFC9@1224|Proteobacteria,2UFYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_104	1429851.X548_06100	4.43e-05	58.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1X4WB@135614|Xanthomonadales	135614|Xanthomonadales	DM	membrane	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
DEZH2_k127_7666303_85	935866.JAER01000019_gene3991	1.541e-08	70.0	COG3568@1|root,COG3568@2|Bacteria,2H48F@201174|Actinobacteria,4DUHI@85009|Propionibacteriales	201174|Actinobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DEZH2_k127_7666303_13	479433.Caci_4080	6.969e-117	398.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
DEZH2_k127_7666303_77	886882.PPSC2_p0161	8.337e-15	84.0	2DQGV@1|root,336S4@2|Bacteria,1VJ0B@1239|Firmicutes,4HZH4@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_106	909613.UO65_0100	0.0001071	53.0	28HZQ@1|root,2Z84P@2|Bacteria,2H0F4@201174|Actinobacteria,4DYNP@85010|Pseudonocardiales	201174|Actinobacteria	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
DEZH2_k127_7666303_60	1451261.AS96_14610	3.937e-27	124.0	COG3704@1|root,COG3704@2|Bacteria	2|Bacteria	U	protein secretion by the type IV secretion system	-	-	-	ko:K03201	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbL
DEZH2_k127_7666303_112	1206731.BAGB01000162_gene7871	0.0006441	47.0	2EEUC@1|root,338MW@2|Bacteria,2IQC9@201174|Actinobacteria,4G316@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbC
DEZH2_k127_7666303_74	1121335.Clst_0952	3.364e-15	81.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24U24@186801|Clostridia,3WJ3V@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DEZH2_k127_7666303_64	700015.Corgl_0432	9.111e-23	106.0	COG1040@1|root,COG1040@2|Bacteria,2HUUT@201174|Actinobacteria,4CVQ0@84998|Coriobacteriia	84998|Coriobacteriia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
DEZH2_k127_7666303_94	194867.ALBQ01000011_gene384	2.702e-06	50.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW4W@28211|Alphaproteobacteria,2JZYG@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug
DEZH2_k127_7666303_59	1123277.KB893195_gene5613	3.918e-27	116.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,47Q95@768503|Cytophagia	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DEZH2_k127_7666303_53	1045009.AFXQ01000006_gene1027	1.952e-37	146.0	COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,1W9C2@1268|Micrococcaceae	201174|Actinobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
DEZH2_k127_7666303_1	264732.Moth_0532	2.571e-203	661.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,42ET0@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DEZH2_k127_7666303_17	292459.STH2921	1.567e-101	341.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DEZH2_k127_7666303_22	717605.Theco_2322	1.41e-81	287.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,26R8F@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_7666303_6	1499967.BAYZ01000069_gene1873	4.928e-151	497.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgcA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DEZH2_k127_7666303_67	537972.ABQU01000083_gene1224	2.306e-20	93.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2YPT9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DEZH2_k127_7666303_7	926550.CLDAP_06600	1.089e-149	490.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DEZH2_k127_7666303_96	1122933.JNIY01000003_gene659	4.905e-06	57.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4F0UI@85016|Cellulomonadaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DEZH2_k127_7666303_44	1379698.RBG1_1C00001G1620	1.326e-51	196.0	COG2222@1|root,COG2222@2|Bacteria,2NQVV@2323|unclassified Bacteria	2|Bacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	pgi	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
DEZH2_k127_7666303_36	500635.MITSMUL_04698	7.416e-60	222.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DEZH2_k127_7666303_26	1121887.AUDK01000015_gene853	1.058e-68	243.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia,2NTAX@237|Flavobacterium	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DEZH2_k127_7666303_27	1120973.AQXL01000107_gene1971	4.267e-68	240.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,4HA3H@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
DEZH2_k127_7666303_4	243232.MJ_1174	1.002e-168	545.0	COG0504@1|root,arCOG00063@2157|Archaea,2XTR2@28890|Euryarchaeota,23QIJ@183939|Methanococci	183939|Methanococci	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DEZH2_k127_7666303_20	158822.LH89_05840	2.604e-84	288.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_0608	CoA_binding,Ligase_CoA
DEZH2_k127_7666303_28	1128421.JAGA01000003_gene3005	4.012e-67	241.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009361,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0042709,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261,iPC815.YPO1115,iUMNK88_1353.UMNK88_764,iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
DEZH2_k127_7666303_34	1227739.Hsw_3006	5.555e-60	229.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,47K91@768503|Cytophagia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DEZH2_k127_7666303_83	487796.Flav2ADRAFT_0380	2.492e-12	73.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
DEZH2_k127_7666303_71	574375.BAGA_25910	4.231e-16	81.0	COG1733@1|root,COG1733@2|Bacteria,1VH3Q@1239|Firmicutes,4HNMI@91061|Bacilli,1ZH91@1386|Bacillus	91061|Bacilli	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DEZH2_k127_7666303_57	382464.ABSI01000010_gene3370	1.387e-29	125.0	COG1949@1|root,COG1949@2|Bacteria	2|Bacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
DEZH2_k127_7666303_58	1123023.JIAI01000007_gene1656	2.571e-28	117.0	COG2315@1|root,COG2315@2|Bacteria,2IHRR@201174|Actinobacteria,4E6QI@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
DEZH2_k127_7666303_24	555088.DealDRAFT_0005	2.999e-75	274.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,42JSA@68298|Syntrophomonadaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
DEZH2_k127_7666303_16	1122918.KB907257_gene2787	5.179e-108	359.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,26T4H@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70 factor, region 1.2	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DEZH2_k127_7666303_54	709991.Odosp_1431	1.341e-33	136.0	COG0237@1|root,COG0237@2|Bacteria	2|Bacteria	H	dephospho-CoA kinase activity	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,3.2.2.23,4.2.99.18	ko:K00859,ko:K08309,ko:K10563	ko00770,ko01100,ko03410,map00770,map01100,map03410	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01011,ko03400	-	GH23	iIT341.HP0831	CoaE
DEZH2_k127_7666303_12	471852.Tcur_1607	1.359e-122	410.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4EG2W@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	GO:0000988,GO:0000990,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DEZH2_k127_7666303_3	411467.BACCAP_02250	5.348e-171	567.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,267MY@186813|unclassified Clostridiales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DEZH2_k127_7666303_47	1008457.BAEX01000058_gene410	6.241e-48	175.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia,47I5C@76831|Myroides	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
DEZH2_k127_7666303_68	762948.HMPREF0733_10612	1.068e-17	91.0	COG1011@1|root,COG1011@2|Bacteria,2IKAF@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
DEZH2_k127_7666303_89	1330700.JQNC01000003_gene1590	3.938e-08	64.0	COG3121@1|root,COG3121@2|Bacteria,1WITE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_90	604331.AUHY01000034_gene2427	1.451e-07	58.0	COG1826@1|root,COG1826@2|Bacteria,1WKJM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DEZH2_k127_7666303_56	944564.HMPREF9200_1060	2.801e-31	136.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4H269@909932|Negativicutes	909932|Negativicutes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DEZH2_k127_7666303_72	313606.M23134_08279	4.703e-16	91.0	COG1361@1|root,COG1409@1|root,COG2931@1|root,COG3420@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1409@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria,COG4886@2|Bacteria,4PMET@976|Bacteroidetes	976|Bacteroidetes	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DEZH2_k127_7666303_79	926550.CLDAP_26360	2.961e-14	87.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_101	522306.CAP2UW1_0976	1.39e-05	54.0	2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_38	1403313.AXBR01000009_gene887	9.295e-58	211.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,1ZCC9@1386|Bacillus	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
DEZH2_k127_7666303_80	326427.Cagg_2973	1.971e-13	81.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi,37690@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DEZH2_k127_7666303_93	44251.PDUR_20355	2.353e-06	55.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,26Z41@186822|Paenibacillaceae	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
DEZH2_k127_7666303_105	1035196.HMPREF9998_00091	4.809e-05	56.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,25R43@186804|Peptostreptococcaceae	186801|Clostridia	S	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DEZH2_k127_7666303_75	316274.Haur_0453	6.832e-15	83.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
DEZH2_k127_7666303_42	648996.Theam_0905	7.921e-53	193.0	COG0130@1|root,COG0130@2|Bacteria,2G40M@200783|Aquificae	200783|Aquificae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
DEZH2_k127_7666303_65	1122602.ATXP01000002_gene613	1.517e-22	99.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,1W9NP@1268|Micrococcaceae	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DEZH2_k127_7666303_0	903814.ELI_2063	4.987e-204	657.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25V7M@186806|Eubacteriaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DEZH2_k127_7666303_114	1437605.BACT_0602	0.0009869	50.0	2EHAX@1|root,33B2S@2|Bacteria,2HZMY@201174|Actinobacteria,4D0Z4@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_46	525904.Tter_0795	3.84e-49	181.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DEZH2_k127_7666303_11	555079.Toce_1227	1.684e-134	454.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,42F33@68295|Thermoanaerobacterales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
DEZH2_k127_7666303_8	748224.HMPREF9436_01808	2.171e-141	475.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DEZH2_k127_7666303_91	545276.KB898730_gene1472	1.939e-07	61.0	2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,1SMYA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_78	1499967.BAYZ01000179_gene4640	1.932e-14	78.0	COG0360@1|root,COG0360@2|Bacteria,2NQ1Q@2323|unclassified Bacteria	2|Bacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DEZH2_k127_7666303_52	794903.OPIT5_19655	1.334e-37	146.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DEZH2_k127_7666303_76	1191523.MROS_1864	8.124e-15	76.0	COG0238@1|root,COG0238@2|Bacteria	2|Bacteria	J	rRNA binding	rpsR	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DEZH2_k127_7666303_48	1304888.ATWF01000002_gene456	3.664e-46	173.0	COG0231@1|root,COG0231@2|Bacteria,2GEJZ@200930|Deferribacteres	200930|Deferribacteres	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DEZH2_k127_7666303_41	944479.JQLX01000017_gene255	2.584e-53	196.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2M71I@213113|Desulfurellales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
DEZH2_k127_7666303_63	1313172.YM304_00990	8.472e-24	114.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_66	1122138.AQUZ01000048_gene2297	1.508e-20	100.0	COG3764@1|root,COG3764@2|Bacteria,2IRXZ@201174|Actinobacteria,4DRSR@85009|Propionibacteriales	201174|Actinobacteria	M	PFAM peptidase C60, sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
DEZH2_k127_7666303_40	326426.Bbr_0236	3.314e-54	211.0	COG2367@1|root,COG2367@2|Bacteria,2HZMP@201174|Actinobacteria,4D0YE@85004|Bifidobacteriales	201174|Actinobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
DEZH2_k127_7666303_10	762211.BSTEL_1218	4.343e-140	453.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CZBU@85004|Bifidobacteriales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DEZH2_k127_7666303_82	1198452.Jab_1c10470	1.611e-12	76.0	2FH2G@1|root,348X9@2|Bacteria,1P05V@1224|Proteobacteria,2W3Y8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_87	1356854.N007_15055	2.036e-08	63.0	COG4961@1|root,COG4961@2|Bacteria,1V76R@1239|Firmicutes,4HJ1C@91061|Bacilli	91061|Bacilli	U	PFAM TadE family protein	tadE	-	-	-	-	-	-	-	-	-	-	-	TadE
DEZH2_k127_7666303_103	9371.XP_004697066.1	2.707e-05	59.0	KOG4441@1|root,KOG4441@2759|Eukaryota,38FPI@33154|Opisthokonta,3BB3K@33208|Metazoa,3CS4P@33213|Bilateria,480RN@7711|Chordata,48VE6@7742|Vertebrata,3JD5N@40674|Mammalia,35165@311790|Afrotheria	33208|Metazoa	T	Kelch-like protein 3	KLHL3	GO:0000003,GO:0000151,GO:0000209,GO:0001655,GO:0001822,GO:0002009,GO:0003006,GO:0003008,GO:0003014,GO:0003096,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006996,GO:0007010,GO:0007049,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007293,GO:0007300,GO:0007301,GO:0007349,GO:0008092,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0015672,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030001,GO:0030029,GO:0030036,GO:0030154,GO:0030163,GO:0030717,GO:0030723,GO:0030725,GO:0031461,GO:0031463,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0035183,GO:0035239,GO:0035295,GO:0035324,GO:0036211,GO:0042592,GO:0043062,GO:0043063,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045171,GO:0045172,GO:0045478,GO:0048468,GO:0048477,GO:0048513,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051276,GO:0051321,GO:0051603,GO:0051704,GO:0060429,GO:0060562,GO:0060993,GO:0061326,GO:0061333,GO:0061982,GO:0061988,GO:0065007,GO:0065008,GO:0070192,GO:0070293,GO:0070294,GO:0070647,GO:0070936,GO:0071704,GO:0071840,GO:0072001,GO:0072006,GO:0072009,GO:0072017,GO:0072028,GO:0072073,GO:0072078,GO:0072080,GO:0072088,GO:0072156,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1903046,GO:1990234	-	ko:K10443,ko:K10457	-	-	-	-	ko00000,ko04121	-	-	-	BACK,BTB,Kelch_1
DEZH2_k127_7666303_97	1094466.KQS_10970	5.213e-06	61.0	COG1345@1|root,COG2866@1|root,COG3209@1|root,COG1345@2|Bacteria,COG2866@2|Bacteria,COG3209@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
DEZH2_k127_7666303_98	945713.IALB_0186	1.044e-05	60.0	COG4675@1|root,COG5276@1|root,COG4675@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	3.4.24.40	ko:K01406,ko:K21449	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Collar,Phage_fiber_2
DEZH2_k127_7666303_111	247490.KSU1_C0730	0.0005675	55.0	COG2234@1|root,COG3291@1|root,COG3420@1|root,COG4409@1|root,COG5184@1|root,COG5276@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4409@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	iap	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6	ko:K01179,ko:K03929,ko:K09612,ko:K12287,ko:K19701,ko:K19702	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02044	-	CE10,GH5,GH9	-	Beta_helix,Peptidase_M28
DEZH2_k127_7666303_92	1111069.TCCBUS3UF1_21560	4.558e-07	62.0	COG3121@1|root,COG3121@2|Bacteria,1WITE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_99	1379698.RBG1_1C00001G1691	1.228e-05	57.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	ASH,DUF3324,DUF916
DEZH2_k127_7666303_108	1307436.PBF_03990	0.0003622	52.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8
DEZH2_k127_7666303_86	1449080.JQMV01000003_gene1528	2.007e-08	66.0	COG3121@1|root,COG3121@2|Bacteria,1WIM3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7666303_95	944479.JQLX01000012_gene1050	3.657e-06	55.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2M7CD@213113|Desulfurellales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
DEZH2_k127_7666303_15	1410631.JHWZ01000001_gene1111	1.739e-112	381.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,27IDF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DEZH2_k127_7666303_88	865861.AZSU01000002_gene2942	3.489e-08	64.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,36G24@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DEZH2_k127_7666303_19	648996.Theam_1659	7.787e-92	320.0	COG0056@1|root,COG0056@2|Bacteria,2G3IZ@200783|Aquificae	200783|Aquificae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DEZH2_k127_7666303_100	83219.PM02_18200	1.301e-05	57.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG4932@1|root,COG5295@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1NEXT@1224|Proteobacteria,2TWJE@28211|Alphaproteobacteria,3ZZDP@60136|Sulfitobacter	28211|Alphaproteobacteria	QU	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214
DEZH2_k127_7677030_0	1038866.KB902802_gene7031	7.977e-48	176.0	COG2311@1|root,COG2311@2|Bacteria,1MWHW@1224|Proteobacteria,2UBZQ@28211|Alphaproteobacteria,3JTRV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
DEZH2_k127_7699630_0	1340493.JNIF01000003_gene2443	1.51e-45	172.0	COG0845@1|root,COG0845@2|Bacteria,3Y317@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DEZH2_k127_7799773_0	1131462.DCF50_p1905	6.546e-75	265.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,260I2@186807|Peptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DEZH2_k127_7883522_2	388051.AUFE01000009_gene1853	2.501e-33	134.0	COG3566@1|root,COG3566@2|Bacteria,1RFH7@1224|Proteobacteria,2W8KK@28216|Betaproteobacteria,1KB2N@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2213)	-	-	-	ko:K09960	-	-	-	-	ko00000	-	-	-	DUF2213
DEZH2_k127_7883522_8	1444711.CCJF01000003_gene25	3.315e-19	98.0	COG2369@1|root,COG2369@2|Bacteria	2|Bacteria	K	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,Phage_Mu_F
DEZH2_k127_7883522_4	1123073.KB899241_gene2700	6.883e-31	136.0	COG0463@1|root,COG0463@2|Bacteria,1P8G7@1224|Proteobacteria,1S2FE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
DEZH2_k127_7883522_3	1509403.GW12_00730	6.135e-31	138.0	COG3567@1|root,COG3567@2|Bacteria,1QNPU@1224|Proteobacteria,1S4PU@1236|Gammaproteobacteria,3NMUE@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1073)	-	-	-	ko:K09961	-	-	-	-	ko00000	-	-	-	DUF1073
DEZH2_k127_7883522_0	1121382.JQKG01000001_gene2517	1.407e-76	275.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria	2|Bacteria	K	chromosome segregation	terL	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
DEZH2_k127_7883522_1	231434.JQJH01000013_gene2932	1.603e-34	141.0	2DUN5@1|root,33RC4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
DEZH2_k127_7883522_6	927677.ALVU02000006_gene443	1.231e-23	108.0	COG1196@1|root,COG1196@2|Bacteria,1GEKG@1117|Cyanobacteria	1117|Cyanobacteria	D	DNA (cytosine-5-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dam
DEZH2_k127_7883522_5	883080.HMPREF9697_01826	5.405e-26	112.0	2CA0E@1|root,349DP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7883522_10	1120977.JHUX01000003_gene847	8.015e-13	78.0	2E5GW@1|root,3308F@2|Bacteria,1N8DS@1224|Proteobacteria,1STKW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknwon function (DUF3310)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3310
DEZH2_k127_7883522_7	1341157.RF007C_11465	2.728e-19	97.0	COG1208@1|root,COG1208@2|Bacteria,1UPGU@1239|Firmicutes,25C21@186801|Clostridia,3WSAE@541000|Ruminococcaceae	186801|Clostridia	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7883522_9	1341157.RF007C_11465	6.513e-13	76.0	COG1208@1|root,COG1208@2|Bacteria,1UPGU@1239|Firmicutes,25C21@186801|Clostridia,3WSAE@541000|Ruminococcaceae	186801|Clostridia	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7883522_13	1195246.AGRI_02558	0.0002551	49.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,1S9E4@1236|Gammaproteobacteria,467T2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
DEZH2_k127_7920306_21	1437608.BBIA_2506	6.887e-73	252.0	COG2356@1|root,COG3064@1|root,COG2356@2|Bacteria,COG3064@2|Bacteria,2GJ38@201174|Actinobacteria,4CYVR@85004|Bifidobacteriales	201174|Actinobacteria	L	Excalibur calcium-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,Excalibur
DEZH2_k127_7920306_40	477184.KYC_28242	6.354e-23	105.0	COG4502@1|root,COG4502@2|Bacteria,1N4TB@1224|Proteobacteria,2WFD2@28216|Betaproteobacteria,3T9E2@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	NT5C
DEZH2_k127_7920306_58	443254.Marpi_0032	0.0002536	51.0	COG1051@1|root,COG1051@2|Bacteria,2GDBT@200918|Thermotogae	200918|Thermotogae	F	pfam nudix	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DEZH2_k127_7920306_52	1121924.ATWH01000006_gene1742	1.154e-07	60.0	295RB@1|root,2ZT2P@2|Bacteria,2GZZV@201174|Actinobacteria,4FQ2B@85023|Microbacteriaceae	201174|Actinobacteria	S	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
DEZH2_k127_7920306_1	485913.Krac_10794	8.131e-205	654.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DEZH2_k127_7920306_37	396014.BF93_09360	3.98e-31	133.0	COG0406@1|root,COG0406@2|Bacteria,2HHG4@201174|Actinobacteria,4FCV3@85020|Dermabacteraceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
DEZH2_k127_7920306_19	768670.Calni_1838	5.585e-77	278.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GEXA@200930|Deferribacteres	200930|Deferribacteres	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
DEZH2_k127_7920306_46	1121033.AUCF01000015_gene1408	1.168e-12	81.0	COG0642@1|root,COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,dCache_1
DEZH2_k127_7920306_48	1540257.JQMW01000004_gene404	7.91e-09	68.0	2EYE8@1|root,33RNB@2|Bacteria,1VQZW@1239|Firmicutes,24A7Z@186801|Clostridia,36HSE@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7920306_55	748727.CLJU_c03720	1.364e-06	61.0	2EYE8@1|root,33RNB@2|Bacteria,1VQZW@1239|Firmicutes,24A7Z@186801|Clostridia,36HSE@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7920306_56	1353529.M899_2645	3.371e-06	57.0	COG3210@1|root,COG3420@1|root,COG3210@2|Bacteria,COG3420@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DEZH2_k127_7920306_25	312284.A20C1_01196	1.226e-60	222.0	292NE@1|root,2ZQ69@2|Bacteria,2IKBG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7920306_22	926569.ANT_11300	2.552e-71	263.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DEZH2_k127_7920306_57	485913.Krac_8434	0.0001545	47.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
DEZH2_k127_7920306_45	1121324.CLIT_5c00620	6.313e-13	75.0	COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,24QRE@186801|Clostridia,25RNY@186804|Peptostreptococcaceae	186801|Clostridia	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DEZH2_k127_7920306_26	903814.ELI_3063	3.38e-59	220.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,25V8P@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
DEZH2_k127_7920306_17	1410653.JHVC01000010_gene3564	6.321e-88	309.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,36DMH@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DEZH2_k127_7920306_4	529884.Rhola_00000470	5.541e-122	398.0	COG1054@1|root,COG1054@2|Bacteria,2GMMP@201174|Actinobacteria,4FKV8@85023|Microbacteriaceae	201174|Actinobacteria	S	Rhodanase C-terminal	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
DEZH2_k127_7920306_9	1463864.JOGO01000005_gene4777	4.976e-105	363.0	COG1132@1|root,COG1132@2|Bacteria,2GJWP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	ywjA	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DEZH2_k127_7920306_39	383372.Rcas_1070	2.879e-24	112.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi,375RP@32061|Chloroflexia	32061|Chloroflexia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DEZH2_k127_7920306_23	1035195.HMPREF9997_02632	8.216e-68	236.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,22MGP@1653|Corynebacteriaceae	201174|Actinobacteria	S	Membrane-associated protein	yqjA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DEZH2_k127_7920306_0	1121422.AUMW01000019_gene1791	0.0	1167.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DEZH2_k127_7920306_7	1232683.ADIMK_0249	1.354e-108	368.0	COG2925@1|root,COG2925@2|Bacteria,1MV0U@1224|Proteobacteria,1RM85@1236|Gammaproteobacteria,464RJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2925 Exonuclease I	sbcB	GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575	3.1.11.1	ko:K01141	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_X-T_C,RNase_T
DEZH2_k127_7920306_51	273057.SSO2022	3.199e-08	62.0	COG3327@1|root,arCOG07233@2157|Archaea	2157|Archaea	K	PaaX-like protein C-terminal domain	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
DEZH2_k127_7920306_10	1123501.KB902284_gene2226	5.426e-103	350.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DEZH2_k127_7920306_35	1405498.SSIM_05990	1.564e-36	153.0	COG1388@1|root,COG3942@1|root,COG1388@2|Bacteria,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4I27S@91061|Bacilli,4GX44@90964|Staphylococcaceae	91061|Bacilli	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,LysM
DEZH2_k127_7920306_33	717605.Theco_2484	2.198e-39	162.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,26Q9M@186822|Paenibacillaceae	91061|Bacilli	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
DEZH2_k127_7920306_42	102232.GLO73106DRAFT_00014720	5.709e-17	85.0	COG0816@1|root,COG0816@2|Bacteria,1G5R5@1117|Cyanobacteria	1117|Cyanobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DEZH2_k127_7920306_16	926561.KB900622_gene690	4.727e-90	311.0	COG0849@1|root,COG0849@2|Bacteria,1UD79@1239|Firmicutes,25HUK@186801|Clostridia,3WBK1@53433|Halanaerobiales	186801|Clostridia	D	Cell division protein FtsA	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
DEZH2_k127_7920306_3	479431.Namu_5171	1.533e-184	597.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4ERRJ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DEZH2_k127_7920306_6	1504822.CCNO01000015_gene584	2.626e-115	381.0	COG0482@1|root,COG0482@2|Bacteria,2NNPW@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DEZH2_k127_7920306_44	1230342.CTM_16547	3.227e-14	80.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,36HJ1@31979|Clostridiaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DEZH2_k127_7920306_12	469378.Ccur_01830	2.499e-101	342.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CUWW@84998|Coriobacteriia	84998|Coriobacteriia	E	aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DEZH2_k127_7920306_28	398767.Glov_2238	1.109e-53	201.0	COG0084@1|root,COG2896@1|root,COG0084@2|Bacteria,COG2896@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
DEZH2_k127_7920306_5	580331.Thit_0098	5.676e-120	402.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42EPT@68295|Thermoanaerobacterales	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DEZH2_k127_7920306_34	1123013.AUIC01000005_gene1429	8.246e-39	153.0	COG1496@1|root,COG1496@2|Bacteria	2|Bacteria	S	copper ion binding	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
DEZH2_k127_7920306_27	926569.ANT_03800	3.858e-56	205.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DEZH2_k127_7920306_29	446466.Cfla_0852	1.794e-52	200.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4F0G8@85016|Cellulomonadaceae	201174|Actinobacteria	S	G5	-	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,SLT
DEZH2_k127_7920306_2	1158614.I592_01712	1.427e-195	632.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,4AZ86@81852|Enterococcaceae	91061|Bacilli	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DEZH2_k127_7920306_24	293826.Amet_3578	8.648e-64	227.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,36DIA@31979|Clostridiaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
DEZH2_k127_7920306_8	1382306.JNIM01000001_gene4156	3.568e-106	358.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DEZH2_k127_7920306_15	760142.Hipma_0462	1.046e-98	338.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,2M6H7@213113|Desulfurellales	28221|Deltaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
DEZH2_k127_7920306_13	882.DVU_2906	4.672e-99	338.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NJ4@68525|delta/epsilon subdivisions,2WJXN@28221|Deltaproteobacteria,2M84T@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	umuC	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
DEZH2_k127_7920306_47	488538.SAR116_1469	1.93e-10	66.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria,4BSG4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
DEZH2_k127_7920306_31	290340.AAur_3143	3.195e-47	194.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,1W8B3@1268|Micrococcaceae	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	LGFP,Peptidase_S8,SLH,VCBS
DEZH2_k127_7920306_11	1157943.KB892705_gene706	6.665e-103	362.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,235P5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DEZH2_k127_7920306_30	1449976.KALB_2339	5.805e-52	199.0	COG0476@1|root,COG0476@2|Bacteria,2HQ2F@201174|Actinobacteria,4DZR7@85010|Pseudonocardiales	201174|Actinobacteria	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase,ThiF
DEZH2_k127_7920306_14	641491.DND132_0480	8.816e-99	341.0	COG1541@1|root,COG1541@2|Bacteria,1QEG5@1224|Proteobacteria,4330D@68525|delta/epsilon subdivisions,2WXFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
DEZH2_k127_7920306_18	247490.KSU1_C1116	1.407e-78	277.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DEZH2_k127_7920306_41	913865.DOT_3105	2.32e-17	87.0	COG0745@1|root,COG0745@2|Bacteria,1W37V@1239|Firmicutes,25FYR@186801|Clostridia,267F7@186807|Peptococcaceae	186801|Clostridia	KT	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DEZH2_k127_7920306_36	443143.GM18_1332	3.216e-36	149.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
DEZH2_k127_7920306_20	1297569.MESS2_1100046	6.052e-74	255.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,2TTCH@28211|Alphaproteobacteria,43JZF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
DEZH2_k127_7920306_32	405948.SACE_2727	3.168e-45	172.0	COG1018@1|root,COG1018@2|Bacteria,2HIRR@201174|Actinobacteria,4DYJW@85010|Pseudonocardiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
DEZH2_k127_7920306_59	4558.Sb10g000230.1	0.0008199	48.0	COG3794@1|root,2RXIY@2759|Eukaryota,37TZA@33090|Viridiplantae,3GI3J@35493|Streptophyta,3KZ9U@4447|Liliopsida,3IH81@38820|Poales	35493|Streptophyta	C	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I	PETE	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
DEZH2_k127_7920306_49	1206101.AZXC01000010_gene236	1.037e-08	66.0	2EQEQ@1|root,33I0P@2|Bacteria,2I3DM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7920306_38	369723.Strop_1063	6.572e-27	117.0	COG3545@1|root,COG3545@2|Bacteria,2HQHK@201174|Actinobacteria,4DJK0@85008|Micromonosporales	201174|Actinobacteria	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
DEZH2_k127_8020371_1	1239962.C943_01799	1.515e-32	131.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DEZH2_k127_8020371_0	563192.HMPREF0179_03201	2.685e-71	247.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DEZH2_k127_8035229_0	596151.DesfrDRAFT_2428	1.719e-25	108.0	COG0582@1|root,COG0582@2|Bacteria,1MVFU@1224|Proteobacteria,42RG7@68525|delta/epsilon subdivisions,2WNRB@28221|Deltaproteobacteria,2MBCE@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DEZH2_k127_8082105_0	323098.Nwi_2863	1.637e-115	383.0	COG0433@1|root,COG0433@2|Bacteria,1RBH9@1224|Proteobacteria,2UQMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8129384_0	2880.D7G873	3.131e-60	229.0	COG0553@1|root,COG2940@1|root,COG5076@1|root,KOG1075@1|root,KOG0383@2759|Eukaryota,KOG0384@2759|Eukaryota,KOG1075@2759|Eukaryota,KOG1081@2759|Eukaryota,KOG1474@2759|Eukaryota	2759|Eukaryota	BK	acetylation-dependent protein binding	-	-	2.1.1.43,2.3.1.15,3.6.4.12	ko:K11367,ko:K11424,ko:K11654,ko:K13506,ko:K14437	ko00310,ko00561,ko00564,ko01100,ko01110,ko05202,map00310,map00561,map00564,map01100,map01110,map05202	M00089	R00851,R03875,R03938,R04866,R04867,R09380	RC00003,RC00004,RC00039,RC00041,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000,ko01004,ko03021,ko03036	-	-	-	Bromodomain,Chromo,Helicase_C,PHD,PWWP,RVT_1,SET,SNF2_N,zf-HC5HC2H
DEZH2_k127_8129384_1	72019.SARC_15960T0	8.287e-09	57.0	2D6P3@1|root,2S57C@2759|Eukaryota,3A6RC@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8148467_0	1120973.AQXL01000122_gene194	5.683e-67	241.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,27842@186823|Alicyclobacillaceae	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
DEZH2_k127_8148467_1	1229203.KI301992_gene1696	1.835e-09	58.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,3UWR8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
DEZH2_k127_8317055_0	428125.CLOLEP_01411	3.755e-65	228.0	28J3N@1|root,2Z8ZU@2|Bacteria,1V15Z@1239|Firmicutes,249Z0@186801|Clostridia,3WNJZ@541000|Ruminococcaceae	186801|Clostridia	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
DEZH2_k127_8354097_0	1121472.AQWN01000016_gene456	6.409e-81	281.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,260I2@186807|Peptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DEZH2_k127_8381319_1	76114.p2A229	6.51e-20	89.0	COG4974@1|root,COG4974@2|Bacteria,1QUHS@1224|Proteobacteria,2VM8C@28216|Betaproteobacteria,2KYHS@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
DEZH2_k127_8381319_2	381666.PHG037	1.232e-18	89.0	COG0582@1|root,COG0582@2|Bacteria,1NX90@1224|Proteobacteria,2VJRU@28216|Betaproteobacteria,1K5P0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	integrase recombinase Y4RB (NP_444040))	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DEZH2_k127_8381319_0	76114.p2A228	2.212e-122	394.0	COG0582@1|root,COG0582@2|Bacteria,1NX90@1224|Proteobacteria,2VJRU@28216|Betaproteobacteria,2KXTA@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DEZH2_k127_8541194_0	290397.Adeh_3594	2.104e-177	560.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DEZH2_k127_8860094_0	309801.trd_A0816	2.441e-62	234.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
DEZH2_k127_8862540_0	760192.Halhy_4856	1.868e-105	368.0	COG3210@1|root,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	976|Bacteroidetes	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	SprB
DEZH2_k127_9215186_0	580332.Slit_0760	3.069e-172	542.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,44V2U@713636|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DEZH2_k127_932278_29	371731.Rsw2DRAFT_0714	3.784e-20	95.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,1FB37@1060|Rhodobacter	28211|Alphaproteobacteria	K	TIGRFAM phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_932278_17	1209989.TepiRe1_2808	3.605e-45	184.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42F3M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	yycG	-	2.7.13.3	ko:K07636,ko:K07652	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9
DEZH2_k127_932278_22	1128427.KB904821_gene173	5.974e-35	139.0	COG1666@1|root,COG1666@2|Bacteria,1G50Y@1117|Cyanobacteria,1HAK6@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
DEZH2_k127_932278_38	996637.SGM_2026	0.0002032	51.0	2B44E@1|root,31WUX@2|Bacteria,2IJJ7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_932278_33	1134413.ANNK01000132_gene2677	1.226e-15	90.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,1ZRQU@1386|Bacillus	91061|Bacilli	U	Signal peptidase, peptidase S26	sipT	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DEZH2_k127_932278_37	1333998.M2A_3185	5.12e-05	54.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,4BS7M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
DEZH2_k127_932278_25	1229780.BN381_350110	1.675e-26	113.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,3UWVE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
DEZH2_k127_932278_24	1304865.JAGF01000001_gene3541	3.633e-31	131.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
DEZH2_k127_932278_19	136273.GY22_08120	6.955e-39	152.0	2BG4A@1|root,32A10@2|Bacteria,2HTN7@201174|Actinobacteria,1WBWP@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_932278_21	743718.Isova_2134	1.095e-36	145.0	COG3797@1|root,COG3797@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
DEZH2_k127_932278_14	1122176.KB903543_gene511	1.703e-53	198.0	COG3752@1|root,COG3752@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
DEZH2_k127_932278_34	926564.KI911649_gene1746	2.784e-14	81.0	COG1073@1|root,COG1073@2|Bacteria,2H6JI@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_932278_20	518766.Rmar_0203	1.356e-38	149.0	2BVXG@1|root,32UI7@2|Bacteria,4PEMY@976|Bacteroidetes,1FJBH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
DEZH2_k127_932278_16	1196029.ALIM01000014_gene3844	6.198e-47	171.0	COG4898@1|root,COG4898@2|Bacteria,1V6U6@1239|Firmicutes,4HH1D@91061|Bacilli,1ZG6X@1386|Bacillus	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
DEZH2_k127_932278_9	1380763.BG53_13490	4.61e-73	255.0	COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,26QVF@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2179)	yqfU	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
DEZH2_k127_932278_4	118005.AWNK01000015_gene1025	1.791e-116	385.0	COG0192@1|root,COG0192@2|Bacteria	2|Bacteria	H	methionine adenosyltransferase activity	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DEZH2_k127_932278_0	667014.Thein_1571	0.0	1086.0	COG0610@1|root,COG0610@2|Bacteria,2GHHQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DEZH2_k127_932278_7	718252.FP2_13060	1.458e-85	297.0	COG0732@1|root,COG0732@2|Bacteria,1VV8H@1239|Firmicutes,25N3G@186801|Clostridia,3WPK1@541000|Ruminococcaceae	186801|Clostridia	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
DEZH2_k127_932278_27	335541.Swol_0742	2.219e-23	116.0	2DBQE@1|root,2ZADR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_932278_2	1414720.CBYM010000005_gene1339	3.498e-202	640.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,36DVJ@31979|Clostridiaceae	186801|Clostridia	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
DEZH2_k127_932278_12	77635.BISU_1038	1.982e-60	214.0	COG0671@1|root,COG0671@2|Bacteria,2HZQV@201174|Actinobacteria,4D1AP@85004|Bifidobacteriales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DEZH2_k127_932278_5	77635.BISU_1037	6.384e-109	360.0	COG1597@1|root,COG1597@2|Bacteria,2I4PB@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DEZH2_k127_932278_15	886377.Murru_2889	1.344e-49	182.0	COG4898@1|root,COG4898@2|Bacteria,4NQGY@976|Bacteroidetes,1I2X8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DEZH2_k127_932278_11	1068978.AMETH_1798	1.932e-62	224.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4DZTI@85010|Pseudonocardiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DEZH2_k127_932278_6	66869.JNXG01000020_gene3517	3.024e-103	345.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DEZH2_k127_932278_10	1123258.AQXZ01000017_gene4296	1.177e-64	228.0	COG3064@1|root,COG3064@2|Bacteria,2IPMP@201174|Actinobacteria	201174|Actinobacteria	M	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_932278_39	760192.Halhy_2093	0.0009065	44.0	2EMYX@1|root,33FM2@2|Bacteria,4NY90@976|Bacteroidetes,1IZI6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_932278_8	631362.Thi970DRAFT_04875	2.514e-84	297.0	COG0628@1|root,COG0628@2|Bacteria,1NG06@1224|Proteobacteria,1S1I3@1236|Gammaproteobacteria,1WXUK@135613|Chromatiales	135613|Chromatiales	S	Transmembrane protein 43	-	-	-	-	-	-	-	-	-	-	-	-	TMEM43
DEZH2_k127_932278_23	675635.Psed_5839	2.52e-34	139.0	COG0431@1|root,COG0431@2|Bacteria,2GNFR@201174|Actinobacteria,4E3XA@85010|Pseudonocardiales	201174|Actinobacteria	K	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DEZH2_k127_932278_35	1192034.CAP_5103	2.268e-11	68.0	COG1733@1|root,COG1733@2|Bacteria,1N0WJ@1224|Proteobacteria	1224|Proteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DEZH2_k127_932278_30	56110.Oscil6304_5988	1.043e-17	85.0	COG1308@1|root,COG1308@2|Bacteria,1G83N@1117|Cyanobacteria	1117|Cyanobacteria	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
DEZH2_k127_932278_36	1122175.ATXU01000008_gene318	1.653e-10	72.0	292NE@1|root,2ZQ69@2|Bacteria,2IKBG@201174|Actinobacteria,4FNV9@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_932278_3	1380356.JNIK01000003_gene1243	4.038e-120	413.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4ESAG@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.6	-	-	MMPL
DEZH2_k127_932278_1	979556.MTES_2680	3.132e-212	686.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4FK9T@85023|Microbacteriaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
DEZH2_k127_932278_26	1001240.GY21_04675	1.435e-24	113.0	COG0596@1|root,COG0596@2|Bacteria,2I7C3@201174|Actinobacteria,4FM9Q@85023|Microbacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DEZH2_k127_932278_31	903818.KI912268_gene1085	2.817e-17	86.0	COG0745@1|root,COG0745@2|Bacteria,3Y4GR@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_932278_18	1128421.JAGA01000003_gene3053	5.143e-39	164.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
DEZH2_k127_932278_13	420890.LCGL_0859	4.299e-60	214.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
DEZH2_k127_9343272_0	1086011.HJ01_01869	2.106e-51	192.0	COG0668@1|root,COG0668@2|Bacteria,4NH7C@976|Bacteroidetes,1ICX5@117743|Flavobacteriia,2NVTM@237|Flavobacterium	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
DEZH2_k127_9355037_0	1121286.AUMT01000013_gene2596	0.0006341	44.0	2BIYZ@1|root,32D7D@2|Bacteria,4PGIF@976|Bacteroidetes,1IM28@117743|Flavobacteriia,3ZTXB@59732|Chryseobacterium	976|Bacteroidetes	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	NUMOD4
DEZH2_k127_9882455_0	760192.Halhy_5729	9.786e-15	85.0	COG1404@1|root,COG3209@1|root,COG3210@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	976|Bacteroidetes	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	SprB
DEZH2_k127_9910763_0	159749.K0TJ16	3.476e-66	232.0	COG2801@1|root,KOG0017@2759|Eukaryota	159749.K0TJ16|-	L	transposition, RNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	-
## 832 queries scanned
## Total time (seconds): 22.888882637023926
## Rate: 36.35 q/s