## Sat Dec 13 08:05:27 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/DEZH2_bin.8.fa -m mmseqs --itype genome -o DEZH2_bin.8 --output_dir /data/result/bins/wyx/egg/DEZH2_bin.8 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DEZH2_k127_1009621_2	1392487.JIAD01000001_gene1789	6.956e-28	118.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,25VCX@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DEZH2_k127_1009621_1	926550.CLDAP_04380	5.682e-37	153.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
DEZH2_k127_1009621_0	1123386.AUIW01000008_gene1891	7.433e-136	449.0	COG0606@1|root,COG0606@2|Bacteria,1WI18@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATPase with chaperone activity	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DEZH2_k127_1009621_3	1244869.H261_19541	2.507e-05	46.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
DEZH2_k127_10343085_15	1267535.KB906767_gene2461	3.711e-07	57.0	2CB8T@1|root,349A2@2|Bacteria,3Y8JH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
DEZH2_k127_10343085_5	28377.ENSACAP00000008874	5.293e-53	190.0	COG0494@1|root,2S254@2759|Eukaryota,39ZYW@33154|Opisthokonta,3BPBN@33208|Metazoa,3D6IS@33213|Bilateria,47Z58@7711|Chordata,498HZ@7742|Vertebrata	33208|Metazoa	L	Nudix (Nucleoside diphosphate linked moiety X)-type motif 1	NUDT1	GO:0000003,GO:0001669,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006259,GO:0006281,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0007154,GO:0007275,GO:0007548,GO:0007568,GO:0008150,GO:0008152,GO:0008406,GO:0008413,GO:0008584,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0012505,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022414,GO:0030141,GO:0030515,GO:0031090,GO:0031410,GO:0031668,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032501,GO:0032502,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0036219,GO:0042221,GO:0042262,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044713,GO:0044714,GO:0045137,GO:0046060,GO:0046061,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046546,GO:0046661,GO:0046686,GO:0046700,GO:0047429,GO:0047693,GO:0048513,GO:0048608,GO:0048731,GO:0048856,GO:0050896,GO:0051716,GO:0055086,GO:0061458,GO:0070013,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0090304,GO:0097159,GO:0097223,GO:0097708,GO:0099503,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.6.1.55,3.6.1.56	ko:K03574,ko:K17816	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DEZH2_k127_10343085_14	365044.Pnap_3218	4.052e-08	54.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,2VVVS@28216|Betaproteobacteria,4AF6Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
DEZH2_k127_10343085_16	1437882.AZRU01000084_gene6773	1.686e-06	51.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,1YGNV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
DEZH2_k127_10343085_8	297246.lpp1603	1.005e-39	155.0	2D6MI@1|root,30AQT@2|Bacteria,1P8HC@1224|Proteobacteria,1T7XG@1236|Gammaproteobacteria,1JFZQ@118969|Legionellales	118969|Legionellales	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
DEZH2_k127_10343085_17	926560.KE387023_gene3628	6.637e-06	57.0	COG2267@1|root,COG2267@2|Bacteria,1WJIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Alpha beta hydrolase	-	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,CMD
DEZH2_k127_10343085_11	1441930.Z042_02000	2.913e-21	103.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
DEZH2_k127_10343085_9	2002.JOEQ01000004_gene2541	6.82e-38	157.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4EIFG@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DEZH2_k127_10343085_13	1419583.V466_01195	4.583e-10	68.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria,1YPEV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	dedA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DEZH2_k127_10343085_19	153496.JNAB01000031_gene1661	5.331e-05	55.0	COG0508@1|root,COG2267@1|root,COG0508@2|Bacteria,COG2267@2|Bacteria,1QV8J@1224|Proteobacteria,2TWDF@28211|Alphaproteobacteria,2JYTS@204441|Rhodospirillales	204441|Rhodospirillales	CI	Biotin-requiring enzyme	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Biotin_lipoyl
DEZH2_k127_10343085_18	667015.Bacsa_0095	4.708e-05	53.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,2FRZ1@200643|Bacteroidia,4AQJS@815|Bacteroidaceae	976|Bacteroidetes	F	Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
DEZH2_k127_10343085_0	1123376.AUIU01000014_gene604	2.375e-263	834.0	COG0653@1|root,COG0653@2|Bacteria,3J0E5@40117|Nitrospirae	40117|Nitrospirae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
DEZH2_k127_10343085_4	1121104.AQXH01000002_gene660	1.308e-84	291.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
DEZH2_k127_10343085_7	929703.KE386491_gene1828	1.806e-40	171.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DEZH2_k127_10343085_3	330214.NIDE2984	1.79e-120	402.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,3J0FF@40117|Nitrospirae	40117|Nitrospirae	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	2.7.7.13,5.3.1.8	ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
DEZH2_k127_10343085_1	1121405.dsmv_3439	1.373e-167	536.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,2MJ21@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DEZH2_k127_10343085_10	395961.Cyan7425_5226	8.277e-34	136.0	COG1051@1|root,COG1051@2|Bacteria,1GEI3@1117|Cyanobacteria	1117|Cyanobacteria	F	NUDIX domain	-	-	-	ko:K03207	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
DEZH2_k127_10343085_2	349161.Dred_1395	7.652e-149	477.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DEZH2_k127_10343085_6	926556.Echvi_2595	2.02e-47	178.0	COG3774@1|root,COG3774@2|Bacteria,4NJH2@976|Bacteroidetes,47WMY@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase sugar-binding region containing DXD motif	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Gb3_synth,Gly_transf_sug
DEZH2_k127_10343085_12	1127692.HMPREF9075_01937	1.595e-14	83.0	COG1215@1|root,COG1215@2|Bacteria,4P1UV@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DEZH2_k127_10528897_7	243164.DET0580	2.733e-06	55.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,34CSZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
DEZH2_k127_10528897_0	744872.Spica_1181	5.28e-242	788.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
DEZH2_k127_10528897_6	247490.KSU1_C0347	1.819e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DEZH2_k127_10528897_2	313606.M23134_07081	5.649e-10	74.0	COG0729@1|root,COG0729@2|Bacteria,4NVBC@976|Bacteroidetes,47Y1F@768503|Cytophagia	976|Bacteroidetes	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DEZH2_k127_10528897_3	1121895.Q765_06475	9.791e-10	73.0	COG5295@1|root,COG5295@2|Bacteria,4NR12@976|Bacteroidetes,1IIJ9@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_10528897_1	216432.CA2559_06760	9.317e-23	116.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DEZH2_k127_10528897_4	945713.IALB_2065	1.341e-08	63.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.43	ko:K05827,ko:K05844	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RimK
DEZH2_k127_10684748_1	760568.Desku_2536	4.741e-22	98.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,262DU@186807|Peptococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DEZH2_k127_10684748_0	1047013.AQSP01000107_gene2079	1.396e-54	198.0	COG1432@1|root,COG1432@2|Bacteria,2NRX6@2323|unclassified Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
DEZH2_k127_1142206_0	1174504.AJTN02000228_gene1933	1.301e-181	586.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2c,tRNA_SAD
DEZH2_k127_1142206_1	555079.Toce_1067	4.579e-14	76.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42H76@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
DEZH2_k127_1378851_3	471857.Svir_08840	2.441e-05	53.0	COG2259@1|root,COG2259@2|Bacteria,2GJCF@201174|Actinobacteria,4E4RP@85010|Pseudonocardiales	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
DEZH2_k127_1378851_2	1089439.KB902241_gene1003	2.115e-22	103.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RWFS@1236|Gammaproteobacteria,462NG@72273|Thiotrichales	72273|Thiotrichales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
DEZH2_k127_1378851_0	401526.TcarDRAFT_0188	8.171e-74	264.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H2VD@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K01928,ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_1378851_1	697303.Thewi_1155	9.901e-33	134.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,42G9A@68295|Thermoanaerobacterales	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DEZH2_k127_1430856_0	643867.Ftrac_2073	5.429e-77	265.0	COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,47P1Y@768503|Cytophagia	976|Bacteroidetes	K	PFAM ATP cone domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
DEZH2_k127_1430856_1	314230.DSM3645_15850	1.669e-21	100.0	COG1285@1|root,COG1285@2|Bacteria,2J0QS@203682|Planctomycetes	203682|Planctomycetes	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
DEZH2_k127_1430856_2	105420.BBPO01000002_gene7556	2.56e-13	77.0	2CHG4@1|root,32WRW@2|Bacteria,2IFE9@201174|Actinobacteria,2NN3I@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_1634065_1	1157708.KB907454_gene2941	2.482e-12	78.0	COG4447@1|root,COG4886@1|root,COG4447@2|Bacteria,COG4886@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_1634065_0	382464.ABSI01000010_gene3321	4.755e-18	98.0	COG2706@1|root,COG3210@1|root,COG4733@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
DEZH2_k127_174826_12	644966.Tmar_1538	1.734e-11	65.0	2BY2H@1|root,32R2G@2|Bacteria,1VUIG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_174826_13	459349.CLOAM1353	1.973e-08	65.0	COG0739@1|root,COG0739@2|Bacteria,2NPTX@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DEZH2_k127_174826_7	1047013.AQSP01000118_gene1245	2.539e-20	93.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Peptidase_M78,UPF0175
DEZH2_k127_174826_11	1227360.C176_07162	2.032e-12	78.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,26DC4@186818|Planococcaceae	91061|Bacilli	E	Zinc carboxypeptidase	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
DEZH2_k127_174826_4	326427.Cagg_0037	5.614e-29	128.0	COG2866@1|root,COG2866@2|Bacteria,2GB4F@200795|Chloroflexi,3751R@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DEZH2_k127_174826_8	1313304.CALK_1905	2.286e-19	94.0	COG2954@1|root,COG2954@2|Bacteria	2|Bacteria	S	triphosphatase activity	-	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0050355	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
DEZH2_k127_174826_14	1469607.KK073768_gene2021	3.75e-06	57.0	COG3409@1|root,COG3409@2|Bacteria,1G0G8@1117|Cyanobacteria,1HKK0@1161|Nostocales	1117|Cyanobacteria	M	peptidoglycan-binding domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
DEZH2_k127_174826_2	1504672.669783264	4.582e-43	162.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2VTIJ@28216|Betaproteobacteria,4AFM3@80864|Comamonadaceae	28216|Betaproteobacteria	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
DEZH2_k127_174826_3	880071.Fleli_3532	6.59e-37	146.0	COG1670@1|root,COG4106@1|root,COG1670@2|Bacteria,COG4106@2|Bacteria,4NTTP@976|Bacteroidetes,47R61@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Acetyltransf_4
DEZH2_k127_174826_9	367299.JOEE01000006_gene779	2.469e-18	95.0	COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria,4FGHF@85021|Intrasporangiaceae	201174|Actinobacteria	G	phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
DEZH2_k127_174826_15	479435.Kfla_2284	5.475e-05	54.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4DNFI@85009|Propionibacteriales	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DEZH2_k127_174826_0	1278073.MYSTI_01906	9.395e-109	369.0	2C5MK@1|root,3010G@2|Bacteria,1RA3G@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_174826_10	595460.RRSWK_02687	2.56e-14	74.0	COG1278@1|root,COG1278@2|Bacteria,2J13Y@203682|Planctomycetes	203682|Planctomycetes	K	COG1278 Cold shock	-	-	-	-	-	-	-	-	-	-	-	-	CSD
DEZH2_k127_174826_1	292459.STH2398	9.456e-52	204.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
DEZH2_k127_174826_6	1038859.AXAU01000002_gene388	7.621e-22	99.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg
DEZH2_k127_174826_5	1121897.AUGO01000003_gene2065	3e-24	115.0	COG1345@1|root,COG3210@1|root,COG3291@1|root,COG3656@1|root,COG1345@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3656@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DEZH2_k127_1783637_0	395494.Galf_0171	9.621e-05	51.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,44W29@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
DEZH2_k127_1813670_1	1123386.AUIW01000003_gene860	7.014e-12	74.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DEZH2_k127_1813670_0	1382306.JNIM01000001_gene2994	4.154e-22	104.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
DEZH2_k127_2005672_0	1379698.RBG1_1C00001G1686	6.94e-264	824.0	COG1217@1|root,COG1217@2|Bacteria,2NNY7@2323|unclassified Bacteria	2|Bacteria	T	Elongation factor G C-terminus	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
DEZH2_k127_2005672_9	1033739.CAEU01000060_gene49	1.013e-20	101.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,26EX8@186818|Planococcaceae	91061|Bacilli	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DEZH2_k127_2005672_3	1267533.KB906733_gene2984	2.041e-87	298.0	COG0191@1|root,COG0191@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	agaY	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
DEZH2_k127_2005672_8	998674.ATTE01000001_gene3277	1.822e-23	112.0	COG0524@1|root,COG0524@2|Bacteria,1QTMT@1224|Proteobacteria,1S1JQ@1236|Gammaproteobacteria,4619G@72273|Thiotrichales	72273|Thiotrichales	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DEZH2_k127_2005672_1	1121924.ATWH01000014_gene3393	2.071e-105	351.0	COG3958@1|root,COG3958@2|Bacteria,2I8VM@201174|Actinobacteria,4FKW5@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DEZH2_k127_2005672_6	1121333.JMLH01000062_gene1411	4.454e-30	126.0	COG0221@1|root,COG0221@2|Bacteria,1VB6Q@1239|Firmicutes,3VR4D@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Inorganic pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Pyrophosphatase
DEZH2_k127_2005672_2	1121924.ATWH01000014_gene3392	1.735e-98	331.0	COG3959@1|root,COG3959@2|Bacteria,2GJ6M@201174|Actinobacteria,4FN7S@85023|Microbacteriaceae	201174|Actinobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DEZH2_k127_2005672_7	886293.Sinac_3210	8.171e-28	122.0	COG0036@1|root,COG0036@2|Bacteria,2IZKC@203682|Planctomycetes	203682|Planctomycetes	G	TIGRFAM Ribulose-phosphate 3-epimerase	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DEZH2_k127_2005672_4	1408473.JHXO01000005_gene1669	3.633e-48	176.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
DEZH2_k127_2005672_5	509635.N824_02360	7.078e-46	169.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IQAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DEZH2_k127_2115545_2	546269.HMPREF0389_01267	6.599e-18	90.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,25RB4@186804|Peptostreptococcaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DEZH2_k127_2115545_0	1321814.HMPREF9089_01136	2.384e-144	486.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,25UTU@186806|Eubacteriaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DEZH2_k127_2115545_1	760142.Hipma_0827	1.152e-123	417.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DEZH2_k127_236843_2	679926.Mpet_1492	4.121e-43	164.0	COG0642@1|root,COG2202@1|root,arCOG06192@2157|Archaea,arCOG06193@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
DEZH2_k127_236843_3	1437824.BN940_09306	5.125e-37	144.0	COG5002@1|root,COG5113@1|root,COG3236@2|Bacteria,COG5002@2|Bacteria,1RI2X@1224|Proteobacteria	1224|Proteobacteria	T	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_4
DEZH2_k127_236843_1	864702.OsccyDRAFT_0760	9.122e-62	225.0	COG1294@1|root,COG1294@2|Bacteria,1G0PM@1117|Cyanobacteria,1H7ZJ@1150|Oscillatoriales	1117|Cyanobacteria	C	TIGRFAM cytochrome d oxidase, subunit II (cydB)	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iAPECO1_1312.cydB,iJN678.cydB	Cyt_bd_oxida_II
DEZH2_k127_236843_0	941449.dsx2_2171	5.146e-75	262.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42P0J@68525|delta/epsilon subdivisions,2WJJQ@28221|Deltaproteobacteria,2M8T4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
DEZH2_k127_2719293_0	289376.THEYE_A0677	2.241e-106	365.0	COG2804@1|root,COG2804@2|Bacteria,3J0XR@40117|Nitrospirae	40117|Nitrospirae	NU	Type II/IV secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DEZH2_k127_2973324_0	641524.ADICYQ_0300	3.777e-120	400.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DEZH2_k127_3003036_3	309801.trd_0060	3.608e-48	186.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
DEZH2_k127_3003036_1	1121423.JONT01000001_gene2059	6.704e-62	226.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DEZH2_k127_3003036_2	525904.Tter_1347	3.243e-57	213.0	COG0707@1|root,COG0707@2|Bacteria,2NP4Z@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iLJ478.TM0232	Glyco_tran_28_C,Glyco_transf_28
DEZH2_k127_3003036_0	246194.CHY_2340	1.915e-94	327.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DEZH2_k127_3277431_7	357808.RoseRS_3863	1.563e-19	99.0	COG2152@1|root,COG2152@2|Bacteria,2G86G@200795|Chloroflexi,376E1@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DEZH2_k127_3277431_0	204669.Acid345_0692	6.362e-97	344.0	COG2461@1|root,COG4191@1|root,COG5000@1|root,COG2461@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,3Y7B2@57723|Acidobacteria,2JKKQ@204432|Acidobacteriia	204432|Acidobacteriia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS
DEZH2_k127_3277431_6	526225.Gobs_2148	1.193e-33	136.0	COG0662@1|root,COG0662@2|Bacteria,2II1B@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DEZH2_k127_3277431_3	484770.UFO1_3359	5.873e-64	239.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_3_2,Big_5,DUF11,DUF3494
DEZH2_k127_3277431_5	667014.Thein_2094	3.135e-38	148.0	COG0264@1|root,COG0264@2|Bacteria,2GHDX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DEZH2_k127_3277431_4	1120971.AUCA01000011_gene2944	2.552e-54	199.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,27885@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DEZH2_k127_3277431_2	329726.AM1_1247	1.345e-76	267.0	COG0216@1|root,COG0216@2|Bacteria,1FZY4@1117|Cyanobacteria	1117|Cyanobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DEZH2_k127_3277431_8	1121937.AUHJ01000013_gene899	3.884e-09	57.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,468J3@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds the 23S rRNA	rpmE	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DEZH2_k127_3471978_3	404380.Gbem_0792	8.06e-06	57.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	msbA9	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DEZH2_k127_3471978_2	1166130.H650_02395	4.133e-19	95.0	COG0500@1|root,COG0500@2|Bacteria,1MX7K@1224|Proteobacteria,1RSD0@1236|Gammaproteobacteria,3X0MK@547|Enterobacter	1236|Gammaproteobacteria	Q	tellurite resistance protein TehB	tehB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0010035,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046690,GO:0050896	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	DUF1971,TehB
DEZH2_k127_3471978_1	1122173.AXVL01000003_gene1184	4.317e-37	148.0	COG0164@1|root,COG0164@2|Bacteria,379TK@32066|Fusobacteria	32066|Fusobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DEZH2_k127_3471978_0	525904.Tter_1074	1.365e-296	942.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
DEZH2_k127_3550754_3	187303.BN69_1880	4.91e-62	224.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	nanK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DEZH2_k127_3550754_2	1336241.JAEB01000002_gene312	7.195e-140	453.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,25UR3@186806|Eubacteriaceae	186801|Clostridia	C	malic enzyme	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
DEZH2_k127_3550754_4	1473546.CH76_06790	4.937e-26	120.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3IW2H@400634|Lysinibacillus	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
DEZH2_k127_3550754_0	1121091.AUMP01000003_gene2526	7.886e-185	598.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,4HBR5@91061|Bacilli	91061|Bacilli	G	Glycoside Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
DEZH2_k127_3550754_1	563192.HMPREF0179_03201	5.88e-167	534.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DEZH2_k127_3556182_2	205914.HS_0534	0.0001425	47.0	COG2026@1|root,COG2026@2|Bacteria,1N8SP@1224|Proteobacteria,1T18F@1236|Gammaproteobacteria,1Y99K@135625|Pasteurellales	135625|Pasteurellales	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
DEZH2_k127_3556182_0	868131.MSWAN_0192	7.284e-92	311.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,23PEV@183925|Methanobacteria	183925|Methanobacteria	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DEZH2_k127_3556182_1	1120985.AUMI01000015_gene1417	5.622e-49	186.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4H3RX@909932|Negativicutes	909932|Negativicutes	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DEZH2_k127_3563752_0	525146.Ddes_0272	1.455e-116	383.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,42RBB@68525|delta/epsilon subdivisions,2X5KT@28221|Deltaproteobacteria,2MGSJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
DEZH2_k127_3563752_2	397287.C807_01438	1.666e-111	370.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia,27IIV@186928|unclassified Lachnospiraceae	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	haeIIIM	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
DEZH2_k127_3563752_7	760142.Hipma_0827	2.179e-61	228.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DEZH2_k127_3563752_23	931276.Cspa_c27210	1.849e-06	57.0	2DRHE@1|root,33BRN@2|Bacteria,1UQQJ@1239|Firmicutes,24UMR@186801|Clostridia,36PMH@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3563752_8	1444711.CCJF01000003_gene8	4.202e-59	221.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,ParBc
DEZH2_k127_3563752_21	309798.COPRO5265_0751	9.751e-14	79.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,42G7Y@68295|Thermoanaerobacterales	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
DEZH2_k127_3563752_17	1004785.AMBLS11_01120	1.176e-19	89.0	2EN2G@1|root,33FQP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3563752_3	32057.KB217483_gene9149	7.608e-103	343.0	COG3621@1|root,COG3621@2|Bacteria,1G4BA@1117|Cyanobacteria,1HU92@1161|Nostocales	1117|Cyanobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
DEZH2_k127_3563752_5	32057.KB217473_gene7803	1.413e-95	329.0	COG1746@1|root,COG1746@2|Bacteria,1GJQ7@1117|Cyanobacteria,1HQAR@1161|Nostocales	1117|Cyanobacteria	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3563752_15	255470.cbdbA1074	1.977e-23	109.0	29B55@1|root,2ZY3K@2|Bacteria,2GAYB@200795|Chloroflexi,34DK2@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3563752_18	224325.AF_1661	1.844e-19	101.0	arCOG05861@1|root,arCOG05861@2157|Archaea,2Y00V@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3563752_22	335543.Sfum_3524	3.54e-10	72.0	2ECVV@1|root,336T6@2|Bacteria,1NFUV@1224|Proteobacteria,432T1@68525|delta/epsilon subdivisions,2WXI4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3563752_24	1121945.ATXS01000009_gene1697	0.0001868	53.0	COG2304@1|root,arCOG02902@2157|Archaea,2XZJD@28890|Euryarchaeota,23X73@183963|Halobacteria	183963|Halobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
DEZH2_k127_3563752_16	1348908.KI518655_gene1541	1.738e-22	104.0	COG0681@1|root,COG0681@2|Bacteria,1V2HE@1239|Firmicutes,4HFVV@91061|Bacilli,1ZFV9@1386|Bacillus	91061|Bacilli	U	Signal peptidase	sipW	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DEZH2_k127_3563752_20	1128421.JAGA01000003_gene3303	4.605e-14	86.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	isp	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PP2C_2
DEZH2_k127_3563752_12	1476973.JMMB01000007_gene1243	5.102e-28	129.0	COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,2486W@186801|Clostridia,25SN4@186804|Peptostreptococcaceae	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DEZH2_k127_3563752_10	306281.AJLK01000103_gene3378	1.126e-31	129.0	COG3600@1|root,COG3600@2|Bacteria,1G6BW@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
DEZH2_k127_3563752_13	521045.Kole_0861	5.531e-25	114.0	COG2890@1|root,COG2890@2|Bacteria,2GCZ7@200918|Thermotogae	200918|Thermotogae	J	Belongs to the protein N5-glutamine methyltransferase family	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DEZH2_k127_3563752_6	1265502.KB905972_gene1345	8.012e-62	224.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,4A9PC@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
DEZH2_k127_3563752_1	646529.Desaci_3751	3.673e-116	386.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,260UE@186807|Peptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DEZH2_k127_3563752_9	1382306.JNIM01000001_gene41	6.528e-55	207.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DEZH2_k127_3563752_19	1408416.JNJT01000005_gene1096	1.537e-14	78.0	COG0319@1|root,COG0319@2|Bacteria,3WTYW@544448|Tenericutes	544448|Tenericutes	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
DEZH2_k127_3563752_4	311424.DhcVS_6	2.902e-97	334.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi,34CWB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	histidyl-tRNA aminoacylation	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DEZH2_k127_3563752_11	760568.Desku_2139	1.709e-31	130.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DEZH2_k127_3563752_14	1319815.HMPREF0202_01249	4.146e-24	106.0	COG0193@1|root,COG0193@2|Bacteria,379XT@32066|Fusobacteria	32066|Fusobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DEZH2_k127_3638331_7	196164.23494156	1.127e-11	75.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
DEZH2_k127_3638331_2	1382356.JQMP01000003_gene2372	3.579e-28	122.0	COG1385@1|root,COG1385@2|Bacteria,2G70G@200795|Chloroflexi,27YEX@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
DEZH2_k127_3638331_6	511680.BUTYVIB_01127	7.515e-20	91.0	COG3041@1|root,COG3041@2|Bacteria,1VCQT@1239|Firmicutes,25D4U@186801|Clostridia	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
DEZH2_k127_3638331_8	764291.STRUR_1994	5.12e-10	64.0	COG3077@1|root,COG3077@2|Bacteria,1VMG5@1239|Firmicutes	1239|Firmicutes	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
DEZH2_k127_3638331_3	1037409.BJ6T_87540	1.736e-25	114.0	COG5457@1|root,COG5457@2|Bacteria,1R88R@1224|Proteobacteria,2U52T@28211|Alphaproteobacteria,3JWW1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1127)	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3638331_4	1037409.BJ6T_87540	7.969e-23	106.0	COG5457@1|root,COG5457@2|Bacteria,1R88R@1224|Proteobacteria,2U52T@28211|Alphaproteobacteria,3JWW1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1127)	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3638331_1	458233.MCCL_0519	8.638e-87	290.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,4GY2Y@90964|Staphylococcaceae	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DEZH2_k127_3638331_0	246194.CHY_1168	1.401e-133	442.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,42F5Q@68295|Thermoanaerobacterales	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DEZH2_k127_3638331_5	436717.AOLE_10565	2.656e-20	93.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,3NNVG@468|Moraxellaceae	1236|Gammaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DEZH2_k127_3655008_2	998674.ATTE01000001_gene126	2.321e-63	231.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,460BS@72273|Thiotrichales	72273|Thiotrichales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
DEZH2_k127_3655008_11	573370.DMR_28470	4.708e-05	53.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2MBZA@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
DEZH2_k127_3655008_5	370438.PTH_2565	2.54e-52	199.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DEZH2_k127_3655008_3	1321779.HMPREF1984_01407	1.311e-54	209.0	COG2148@1|root,COG2148@2|Bacteria,378EQ@32066|Fusobacteria	32066|Fusobacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
DEZH2_k127_3655008_1	1303518.CCALI_02167	3.78e-69	245.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DEZH2_k127_3655008_7	1227349.C170_16185	5.49e-13	76.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HIM1@91061|Bacilli,26ZB1@186822|Paenibacillaceae	91061|Bacilli	I	bacitracin transport permease	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,PAP2_3
DEZH2_k127_3655008_0	388467.A19Y_0874	1.512e-86	303.0	COG0342@1|root,COG0342@2|Bacteria,1G053@1117|Cyanobacteria,1H7U4@1150|Oscillatoriales	1117|Cyanobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DEZH2_k127_3655008_4	479434.Sthe_1727	3.708e-54	201.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DEZH2_k127_3655008_6	1284352.AOIG01000064_gene935	4.994e-16	79.0	2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes,4IAYB@91061|Bacilli,273DA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3655008_9	211165.AJLN01000020_gene2779	4.699e-09	59.0	2EG09@1|root,339SB@2|Bacteria,1GGEA@1117|Cyanobacteria,1JMPR@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3655008_8	1122619.KB892364_gene1143	2.233e-10	61.0	2EK6X@1|root,33DXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3655008_10	1121870.AUAA01000078_gene1196	8.745e-09	57.0	2DMHR@1|root,32RMI@2|Bacteria,4NUR9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3720237_2	1158338.JNLJ01000001_gene687	7.383e-05	51.0	COG4970@1|root,COG4970@2|Bacteria,2G4CK@200783|Aquificae	200783|Aquificae	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	N_methyl
DEZH2_k127_3720237_1	1511.CLOST_0186	6.266e-65	238.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,25QTI@186804|Peptostreptococcaceae	186801|Clostridia	U	Bacterial type II secretion system	tapC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DEZH2_k127_3720237_0	373903.Hore_05970	2.216e-135	451.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WAAY@53433|Halanaerobiales	186801|Clostridia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DEZH2_k127_3761996_0	521098.Aaci_0301	1.146e-104	350.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,278UP@186823|Alicyclobacillaceae	91061|Bacilli	NU	type II secretion system protein E	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
DEZH2_k127_3761996_1	1382315.JPOI01000001_gene1659	2.338e-52	200.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,4HBFI@91061|Bacilli,1WF24@129337|Geobacillus	91061|Bacilli	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DEZH2_k127_3761996_2	1121887.AUDK01000011_gene219	2.125e-27	115.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1IMU3@117743|Flavobacteriia,2P0M0@237|Flavobacterium	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DEZH2_k127_3761996_4	1219080.VEZ01S_02_00990	0.0002234	50.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XYET@135623|Vibrionales	135623|Vibrionales	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
DEZH2_k127_3761996_5	926550.CLDAP_26360	0.0006417	53.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_3761996_3	766499.C357_00839	5.773e-16	92.0	28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2793
DEZH2_k127_3812906_0	263820.PTO0637	1.126e-39	155.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,242AD@183967|Thermoplasmata	183967|Thermoplasmata	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
DEZH2_k127_3812906_2	1137799.GZ78_03280	4.552e-06	54.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1XKFR@135619|Oceanospirillales	135619|Oceanospirillales	J	seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
DEZH2_k127_3812906_1	395961.Cyan7425_4156	1.215e-06	54.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	CP_0257	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DEZH2_k127_4033648_0	545695.TREAZ_0059	2.939e-172	552.0	COG0495@1|root,COG0495@2|Bacteria,2J5BV@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
DEZH2_k127_4033648_3	1123371.ATXH01000032_gene455	5.55e-07	61.0	COG0568@1|root,COG0568@2|Bacteria,2GGSB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DEZH2_k127_4033648_4	796606.BMMGA3_16765	8.182e-06	58.0	COG0433@1|root,COG0433@2|Bacteria,1VBT7@1239|Firmicutes,4HTX5@91061|Bacilli,1ZKHZ@1386|Bacillus	91061|Bacilli	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
DEZH2_k127_4033648_2	591001.Acfer_0899	5.056e-52	197.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4H20Z@909932|Negativicutes	909932|Negativicutes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
DEZH2_k127_4033648_1	565653.EGBG_02239	4.187e-90	309.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,4AZ76@81852|Enterococcaceae	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DEZH2_k127_4194927_3	862971.SANR_1487	2.147e-17	84.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,42ECK@671232|Streptococcus anginosus group	91061|Bacilli	L	GIY-YIG catalytic domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DEZH2_k127_4194927_2	1123248.KB893348_gene308	1.888e-21	97.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1ITVQ@117747|Sphingobacteriia	976|Bacteroidetes	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
DEZH2_k127_4194927_4	1122211.JMLW01000010_gene1267	1.376e-09	63.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1XM4U@135619|Oceanospirillales	135619|Oceanospirillales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DEZH2_k127_4194927_5	562970.Btus_3162	1.158e-08	68.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,4HIQ8@91061|Bacilli,27A6Z@186823|Alicyclobacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	RNDmfp	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DEZH2_k127_4194927_0	1121456.ATVA01000002_gene3203	3.459e-132	459.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DEZH2_k127_4194927_1	1157490.EL26_18065	9.216e-55	200.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,278I2@186823|Alicyclobacillaceae	91061|Bacilli	J	RNA pseudouridylate synthase	-	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DEZH2_k127_4213539_0	1122217.KB899571_gene1112	1.866e-72	253.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4H1X2@909932|Negativicutes	909932|Negativicutes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DEZH2_k127_4213539_1	339860.Msp_0625	1.677e-60	213.0	COG0221@1|root,arCOG01711@2157|Archaea,2XTSU@28890|Euryarchaeota,23P2K@183925|Methanobacteria	183925|Methanobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
DEZH2_k127_4377488_5	525904.Tter_0072	3.691e-22	106.0	COG2220@1|root,COG2220@2|Bacteria,2NR9T@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
DEZH2_k127_4377488_1	37659.JNLN01000001_gene991	4.325e-252	801.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DEZH2_k127_4377488_6	86416.Clopa_2034	5.049e-18	91.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,24G83@186801|Clostridia,36I0B@31979|Clostridiaceae	186801|Clostridia	Q	PFAM ubiE COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31,Ubie_methyltran
DEZH2_k127_4377488_8	690850.Desaf_0986	2.622e-08	66.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,42N79@68525|delta/epsilon subdivisions,2WM0N@28221|Deltaproteobacteria,2MAEC@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_8
DEZH2_k127_4377488_12	980584.AFPB01000174_gene1545	0.0002938	48.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,1I2VE@117743|Flavobacteriia,406HR@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	J	Ribosome-binding factor A	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
DEZH2_k127_4377488_2	1122211.JMLW01000015_gene1515	3.748e-112	380.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1XH9T@135619|Oceanospirillales	135619|Oceanospirillales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
DEZH2_k127_4377488_7	768706.Desor_5629	3.169e-13	76.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,262K8@186807|Peptococcaceae	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
DEZH2_k127_4377488_3	552811.Dehly_0381	3.537e-91	314.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,34CUS@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Beta-eliminating lyase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DEZH2_k127_4377488_4	671143.DAMO_0395	3.831e-79	268.0	COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria	2|Bacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DEZH2_k127_4377488_9	1121370.AQUY01000002_gene1578	6.431e-07	60.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,22KT0@1653|Corynebacteriaceae	201174|Actinobacteria	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
DEZH2_k127_4377488_0	1123371.ATXH01000007_gene516	1.36e-263	830.0	COG0542@1|root,COG0542@2|Bacteria,2GGRY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DEZH2_k127_4480246_0	1111135.HMPREF1248_0193	4.7e-30	126.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CUFU@84998|Coriobacteriia	84998|Coriobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
DEZH2_k127_4480246_1	938289.CAJN020000003_gene1023	2.807e-08	57.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,268M8@186813|unclassified Clostridiales	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DEZH2_k127_4953799_7	632335.Calkr_0873	1.568e-22	111.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42FSF@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
DEZH2_k127_4953799_11	1122919.KB905562_gene2460	9.363e-06	58.0	COG0477@1|root,COG2814@2|Bacteria,1UI43@1239|Firmicutes,4ISCR@91061|Bacilli,26RSR@186822|Paenibacillaceae	91061|Bacilli	EGP	Major facilitator superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
DEZH2_k127_4953799_4	1382306.JNIM01000001_gene1570	2.429e-59	214.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi	200795|Chloroflexi	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DEZH2_k127_4953799_3	909663.KI867150_gene1711	4.921e-74	258.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2MQVX@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM HhH-GPD superfamily base excision DNA repair protein	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DEZH2_k127_4953799_12	1144275.COCOR_07025	0.0005282	50.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DEZH2_k127_4953799_5	745718.JADT01000019_gene1519	8.89e-53	192.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
DEZH2_k127_4953799_9	335541.Swol_1248	1.176e-20	104.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,42JWE@68298|Syntrophomonadaceae	186801|Clostridia	S	SMART phosphoesterase PHP domain protein	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
DEZH2_k127_4953799_15	1122217.KB899580_gene1630	0.000952	47.0	COG1525@1|root,COG1525@2|Bacteria,1VK6A@1239|Firmicutes,4H67V@909932|Negativicutes	909932|Negativicutes	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding
DEZH2_k127_4953799_8	376619.FTL_1452	1.589e-22	99.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,460WG@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DEZH2_k127_4953799_10	309803.CTN_1712	2.006e-17	87.0	COG0359@1|root,COG0359@2|Bacteria,2GD71@200918|Thermotogae	200918|Thermotogae	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
DEZH2_k127_4953799_2	1265845.PWEIH_15078	5.362e-77	273.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,26J2D@186820|Listeriaceae	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
DEZH2_k127_4953799_6	1128421.JAGA01000002_gene104	1.126e-37	153.0	COG0598@1|root,COG0598@2|Bacteria,2NQIW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DEZH2_k127_4953799_1	1291050.JAGE01000001_gene1471	1.985e-117	392.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
DEZH2_k127_4953799_13	225117.XP_009350076.1	0.0008285	47.0	COG0050@1|root,COG0480@1|root,KOG0460@2759|Eukaryota,KOG0465@2759|Eukaryota,37K55@33090|Viridiplantae,3G82M@35493|Streptophyta,4JJGU@91835|fabids	35493|Streptophyta	J	Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DEZH2_k127_4953799_0	748449.Halha_2603	4.531e-128	424.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WANE@53433|Halanaerobiales	186801|Clostridia	L	Replicative DNA helicase	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DEZH2_k127_4953799_14	459349.CLOAM0450	0.0008741	42.0	COG0353@1|root,COG0353@2|Bacteria,2NP5N@2323|unclassified Bacteria	2|Bacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
DEZH2_k127_5099198_0	1163617.SCD_n00705	2.705e-126	414.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
DEZH2_k127_5099198_5	865937.Gilli_3120	1.49e-06	60.0	COG3408@1|root,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes,1I02Y@117743|Flavobacteriia	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
DEZH2_k127_5099198_2	869210.Marky_0538	1.113e-28	127.0	COG1397@1|root,COG1397@2|Bacteria,1WNF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
DEZH2_k127_5099198_1	365044.Pnap_4542	1.014e-50	186.0	2C6BU@1|root,32S87@2|Bacteria,1NIFE@1224|Proteobacteria,2VRGB@28216|Betaproteobacteria,4AGT5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5099198_3	552811.Dehly_1001	1.088e-21	99.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi,34DDK@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DEZH2_k127_5099198_4	1121335.Clst_2334	5.543e-21	93.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia	186801|Clostridia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DEZH2_k127_5214536_17	1229172.JQFA01000002_gene4398	0.0008326	44.0	COG1230@1|root,COG1230@2|Bacteria,1G719@1117|Cyanobacteria,1HBUK@1150|Oscillatoriales	1117|Cyanobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
DEZH2_k127_5214536_6	1121920.AUAU01000010_gene16	1.371e-26	114.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria	57723|Acidobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DEZH2_k127_5214536_5	1131269.AQVV01000009_gene1132	4.596e-42	164.0	COG0564@1|root,COG0564@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluD	GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	iE2348C_1286.E2348C_2868,iECED1_1282.ECED1_3035,iECSF_1327.ECSF_2432	PseudoU_synth_2,S4
DEZH2_k127_5214536_4	596320.NEIFL0001_2258	2.083e-54	198.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,2KPFY@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DEZH2_k127_5214536_12	518766.Rmar_1812	1.468e-16	85.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,1FJMR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
DEZH2_k127_5214536_7	671143.DAMO_1412	4.609e-20	103.0	COG4972@1|root,COG4972@2|Bacteria,2NPF6@2323|unclassified Bacteria	2|Bacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DEZH2_k127_5214536_3	1382356.JQMP01000004_gene130	6.16e-59	210.0	COG0586@1|root,COG0586@2|Bacteria,2GBDA@200795|Chloroflexi,27YWX@189775|Thermomicrobia	189775|Thermomicrobia	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DEZH2_k127_5214536_10	562970.Btus_0051	1.489e-17	87.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,27850@186823|Alicyclobacillaceae	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DEZH2_k127_5214536_9	944480.ATUV01000002_gene277	1.561e-19	93.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2M79G@213113|Desulfurellales	28221|Deltaproteobacteria	L	Likely ribonuclease with RNase H fold.	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DEZH2_k127_5214536_2	935836.JAEL01000003_gene491	6.557e-84	292.0	COG0778@1|root,COG0778@2|Bacteria,1TRKR@1239|Firmicutes,4HNKJ@91061|Bacilli,1ZJM9@1386|Bacillus	91061|Bacilli	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DEZH2_k127_5214536_8	768704.Desmer_0919	1.076e-19	103.0	COG1388@1|root,COG3409@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,COG3858@2|Bacteria,1V9U8@1239|Firmicutes,24KET@186801|Clostridia,264JR@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1
DEZH2_k127_5214536_14	1033737.CAEV01000017_gene3078	1.248e-07	61.0	COG0308@1|root,COG0308@2|Bacteria,1W0CH@1239|Firmicutes,24PX1@186801|Clostridia,36RJT@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_5214536_13	1280390.CBQR020000114_gene2977	3.915e-12	73.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DEZH2_k127_5214536_1	927658.AJUM01000047_gene2858	9.485e-116	384.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,2FNF4@200643|Bacteroidia,3XJAJ@558415|Marinilabiliaceae	976|Bacteroidetes	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DEZH2_k127_5214536_0	1219084.AP014508_gene104	1.049e-177	588.0	COG0474@1|root,COG0474@2|Bacteria,2GCEM@200918|Thermotogae	200918|Thermotogae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DEZH2_k127_5214536_11	666685.R2APBS1_0223	9.012e-17	94.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,1SG73@1236|Gammaproteobacteria,1X5NU@135614|Xanthomonadales	135614|Xanthomonadales	M	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta,He_PIG
DEZH2_k127_5214536_15	326424.FRAAL6628	2.784e-05	55.0	COG1361@1|root,COG3468@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3468@2|Bacteria,COG4719@2|Bacteria,2I8F1@201174|Actinobacteria	201174|Actinobacteria	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
DEZH2_k127_5239352_4	760142.Hipma_0827	5.705e-10	68.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DEZH2_k127_5239352_0	218497.CAB419	1.117e-164	537.0	COG0481@1|root,COG0481@2|Bacteria,2JFFF@204428|Chlamydiae	204428|Chlamydiae	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DEZH2_k127_5239352_1	1382356.JQMP01000003_gene2578	1.334e-42	175.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
DEZH2_k127_5239352_3	929703.KE386491_gene2674	1.108e-13	77.0	COG1430@1|root,COG1430@2|Bacteria,4NQ5G@976|Bacteroidetes,47R49@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
DEZH2_k127_5239352_2	290512.Paes_0127	2.361e-26	111.0	COG0724@1|root,COG0724@2|Bacteria,1FE64@1090|Chlorobi	1090|Chlorobi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DEZH2_k127_5357325_1	1268240.ATFI01000009_gene1717	6.157e-47	173.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,2FNRV@200643|Bacteroidia,4AN6V@815|Bacteroidaceae	976|Bacteroidetes	F	Nucleoside diphosphate kinase	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DEZH2_k127_5357325_0	313595.P700755_002118	1.707e-89	322.0	COG0433@1|root,COG0784@1|root,COG0433@2|Bacteria,COG0784@2|Bacteria,4NU1B@976|Bacteroidetes,1I4WR@117743|Flavobacteriia	976|Bacteroidetes	T	TraM recognition site of TraD and TraG	-	-	-	-	-	-	-	-	-	-	-	-	TraG-D_C,TrwB_AAD_bind
DEZH2_k127_5851079_4	929704.Myrod_3002	1.305e-18	90.0	COG3708@1|root,COG3708@2|Bacteria,4NQBR@976|Bacteroidetes,1I30N@117743|Flavobacteriia,47IJX@76831|Myroides	976|Bacteroidetes	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2
DEZH2_k127_5851079_5	1026882.MAMP_02093	1.132e-17	90.0	COG1896@1|root,COG1896@2|Bacteria,1MXEZ@1224|Proteobacteria,1RRQQ@1236|Gammaproteobacteria,462Z9@72273|Thiotrichales	72273|Thiotrichales	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
DEZH2_k127_5851079_1	1460634.JCM19037_3583	5.832e-76	269.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli	91061|Bacilli	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DEZH2_k127_5851079_0	264732.Moth_0532	6.137e-209	671.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,42ET0@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DEZH2_k127_5851079_7	926561.KB900620_gene3082	6.302e-11	72.0	COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,24D4U@186801|Clostridia,3WBU4@53433|Halanaerobiales	186801|Clostridia	S	Protease prsW family	prsW	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DEZH2_k127_5851079_6	880072.Desac_0008	1.152e-16	85.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2MS9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DEZH2_k127_5851079_2	2903.EOD27628	1.717e-20	98.0	KOG1584@1|root,KOG1584@2759|Eukaryota	2759|Eukaryota	S	sulfotransferase activity	St1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006805,GO:0006950,GO:0006952,GO:0008146,GO:0008150,GO:0008152,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016740,GO:0016782,GO:0042221,GO:0042742,GO:0043207,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0051923,GO:0070887,GO:0071466,GO:0098542	2.8.2.1,2.8.2.4	ko:K01014,ko:K01016,ko:K01025	ko00140,ko05204,map00140,map05204	-	R01242,R02350	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
DEZH2_k127_5851079_9	1944.JOAZ01000002_gene5578	3.471e-08	63.0	COG3415@1|root,COG3415@2|Bacteria,2HK0D@201174|Actinobacteria,4187W@629295|Streptomyces griseus group	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Terminase_5
DEZH2_k127_5851079_3	660470.Theba_1526	1.734e-19	89.0	COG0695@1|root,COG0695@2|Bacteria,2GD7W@200918|Thermotogae	200918|Thermotogae	O	glutaredoxin-like protein, YruB-family	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DEZH2_k127_6150774_11	1340493.JNIF01000003_gene3476	2.036e-09	61.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	moxJ	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3
DEZH2_k127_6150774_5	1123366.TH3_20363	6.228e-23	113.0	COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria,2UDXB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
DEZH2_k127_6150774_12	1096930.L284_15035	4.587e-05	56.0	COG3210@1|root,COG5301@1|root,COG3210@2|Bacteria,COG5301@2|Bacteria,1PHBB@1224|Proteobacteria,2V8WX@28211|Alphaproteobacteria,2KBRG@204457|Sphingomonadales	204457|Sphingomonadales	U	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DEZH2_k127_6150774_2	552811.Dehly_1171	2.37e-53	194.0	COG1704@1|root,COG1704@2|Bacteria,2GAPS@200795|Chloroflexi,34D06@301297|Dehalococcoidia	301297|Dehalococcoidia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DEZH2_k127_6150774_10	113355.CM001775_gene2407	8.17e-14	73.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
DEZH2_k127_6150774_7	386456.JQKN01000008_gene1488	4.696e-18	85.0	arCOG03086@1|root,arCOG03086@2157|Archaea	2157|Archaea	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DEZH2_k127_6150774_1	1047013.AQSP01000139_gene2394	9.399e-77	267.0	COG0501@1|root,COG0501@2|Bacteria,2NP1V@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
DEZH2_k127_6150774_9	1121930.AQXG01000005_gene641	5.271e-16	83.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_6150774_3	525257.HMPREF0204_12575	4.986e-50	185.0	COG2249@1|root,COG2249@2|Bacteria,4NGIK@976|Bacteroidetes,1I0BM@117743|Flavobacteriia,3ZQIM@59732|Chryseobacterium	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
DEZH2_k127_6150774_0	760192.Halhy_1143	5.756e-150	483.0	COG1680@1|root,COG1680@2|Bacteria,4NIEB@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DEZH2_k127_6150774_8	1158146.KB907124_gene2109	7.721e-17	93.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	2.4.1.9	ko:K20811	ko00500,map00500	-	R04194	RC00077,RC00247	ko00000,ko00001,ko01000	-	GH68	-	Cna_B,FctA,Gram_pos_anchor,MucBP,SdrD_B,YSIRK_signal
DEZH2_k127_6150774_4	383372.Rcas_0199	2.868e-40	155.0	COG1525@1|root,COG1525@2|Bacteria,2G964@200795|Chloroflexi,377C3@32061|Chloroflexia	32061|Chloroflexia	L	PFAM nuclease (SNase domain protein)	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
DEZH2_k127_6150774_6	1304880.JAGB01000002_gene2376	1.602e-21	95.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia	186801|Clostridia	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DEZH2_k127_6174650_13	243164.DET0476	1.741e-09	63.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi,34DEW@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DEZH2_k127_6174650_9	555088.DealDRAFT_1522	1.005e-36	147.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42JTY@68298|Syntrophomonadaceae	186801|Clostridia	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DEZH2_k127_6174650_8	1304885.AUEY01000001_gene3247	1.046e-43	167.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2MJKX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DEZH2_k127_6174650_10	1229520.ADIAL_0612	1.25e-32	130.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,27GDW@186828|Carnobacteriaceae	91061|Bacilli	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DEZH2_k127_6174650_1	1121441.AUCX01000018_gene1493	5.766e-180	571.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2M88A@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DEZH2_k127_6174650_12	429009.Adeg_1011	3.531e-20	94.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_6174650_11	945713.IALB_1034	1.575e-22	101.0	COG0745@1|root,COG0745@2|Bacteria	945713.IALB_1034|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6174650_0	1121428.DESHY_150039___1	3.153e-271	851.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2600F@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DEZH2_k127_6174650_6	1121430.JMLG01000024_gene81	5.128e-46	170.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,261BV@186807|Peptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DEZH2_k127_6174650_3	641524.ADICYQ_2642	5.934e-57	204.0	COG5523@1|root,COG5523@2|Bacteria,4NTWR@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
DEZH2_k127_6174650_2	720554.Clocl_0658	1.386e-58	206.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WIHG@541000|Ruminococcaceae	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DEZH2_k127_6174650_7	224324.aq_1853	9.301e-44	167.0	COG1994@1|root,COG1994@2|Bacteria,2G44C@200783|Aquificae	200783|Aquificae	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
DEZH2_k127_6174650_16	768670.Calni_0700	0.0004131	46.0	COG0227@1|root,COG0227@2|Bacteria,2GG02@200930|Deferribacteres	200930|Deferribacteres	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
DEZH2_k127_6174650_15	202954.BBNK01000003_gene2420	1.405e-05	48.0	COG5301@1|root,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1RR74@1236|Gammaproteobacteria,3NSR5@468|Moraxellaceae	1236|Gammaproteobacteria	S	Phage tail-collar fibre protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF3751,Phage_fiber_2
DEZH2_k127_6174650_4	1049564.TevJSym_bf00250	8.111e-52	205.0	COG2304@1|root,COG3509@1|root,COG4257@1|root,COG2304@2|Bacteria,COG3509@2|Bacteria,COG4257@2|Bacteria,1PDQV@1224|Proteobacteria,1RPGD@1236|Gammaproteobacteria,1J904@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,FG-GAP_2
DEZH2_k127_6174650_5	1449126.JQKL01000011_gene3542	8.218e-49	185.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,268TI@186813|unclassified Clostridiales	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
DEZH2_k127_6174650_14	1094508.Tsac_0192	3.856e-08	59.0	COG0586@1|root,COG0586@2|Bacteria,1U42T@1239|Firmicutes,24EYP@186801|Clostridia,42F2F@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DEZH2_k127_6240856_4	443144.GM21_3561	3.766e-45	188.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,CarboxypepD_reg,DUF11,DUF3494,SdrD_B
DEZH2_k127_6240856_7	471875.RUMLAC_00600	3.657e-12	80.0	COG1196@1|root,COG3669@1|root,COG4447@1|root,COG1196@2|Bacteria,COG3669@2|Bacteria,COG4447@2|Bacteria,1TSG7@1239|Firmicutes,247VJ@186801|Clostridia,3WP00@541000|Ruminococcaceae	186801|Clostridia	DG	F5 8 type C domain protein	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,F5_F8_type_C,FIVAR,Gram_pos_anchor
DEZH2_k127_6240856_9	1029823.AFIE01000093_gene2502	0.0008758	52.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,3NN17@468|Moraxellaceae	1236|Gammaproteobacteria	Q	Bacterial Ig-like domain (group 3)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,VCBS
DEZH2_k127_6240856_5	323098.Nwi_2161	2.362e-39	152.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2U05I@28211|Alphaproteobacteria,3JQPI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
DEZH2_k127_6240856_0	469381.Dpep_1517	1.81e-99	339.0	COG2081@1|root,COG2081@2|Bacteria,3TA5W@508458|Synergistetes	508458|Synergistetes	C	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	HI0933_like
DEZH2_k127_6240856_1	293826.Amet_3997	7.241e-90	319.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
DEZH2_k127_6240856_6	138119.DSY3657	2.612e-14	86.0	COG0845@1|root,COG0845@2|Bacteria,1UUEP@1239|Firmicutes,24CTR@186801|Clostridia,262XV@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DEZH2_k127_6240856_3	1227268.HMPREF1552_01280	1.359e-71	249.0	COG1136@1|root,COG1136@2|Bacteria,3783V@32066|Fusobacteria	32066|Fusobacteria	V	ABC transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
DEZH2_k127_6240856_2	1120973.AQXL01000125_gene3124	1.024e-84	295.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,2795F@186823|Alicyclobacillaceae	91061|Bacilli	V	MacB-like periplasmic core domain	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DEZH2_k127_6240856_8	909663.KI867150_gene2309	1.042e-11	77.0	COG4447@1|root,COG4447@2|Bacteria,1PFB5@1224|Proteobacteria,437G8@68525|delta/epsilon subdivisions,2X2NT@28221|Deltaproteobacteria,2MRPS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6293128_9	1535422.ND16A_2150	1.013e-12	81.0	COG3485@1|root,COG4932@1|root,COG5276@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,CarboxypepD_reg,DUF11,FG-GAP
DEZH2_k127_6293128_10	886882.PPSC2_p0161	6.969e-11	72.0	2DQGV@1|root,336S4@2|Bacteria,1VJ0B@1239|Firmicutes,4HZH4@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6293128_1	479433.Caci_4080	3.629e-108	372.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
DEZH2_k127_6293128_12	1499680.CCFE01000011_gene766	3.604e-09	68.0	COG1876@1|root,COG1876@2|Bacteria,1UBPA@1239|Firmicutes,4IN44@91061|Bacilli,1ZMT0@1386|Bacillus	91061|Bacilli	M	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
DEZH2_k127_6293128_6	138119.DSY5057	5.858e-31	131.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,261MW@186807|Peptococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	oxaA	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
DEZH2_k127_6293128_8	289377.HL41_04070	1.297e-17	84.0	COG0759@1|root,COG0759@2|Bacteria,2GI2Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DEZH2_k127_6293128_14	272134.KB731324_gene6392	0.0002345	49.0	COG0594@1|root,COG0594@2|Bacteria,1G7Z7@1117|Cyanobacteria,1HC5M@1150|Oscillatoriales	1117|Cyanobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DEZH2_k127_6293128_11	1268622.AVS7_00976	1.514e-10	63.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria,4AFCB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DEZH2_k127_6293128_2	1449126.JQKL01000038_gene980	1.21e-103	354.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,267W5@186813|unclassified Clostridiales	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DEZH2_k127_6293128_4	941824.TCEL_02027	3.522e-44	175.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,36E0C@31979|Clostridiaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DEZH2_k127_6293128_0	316274.Haur_3225	2.513e-117	408.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,374XI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
DEZH2_k127_6293128_3	765911.Thivi_3085	3.936e-98	333.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
DEZH2_k127_6293128_5	1408439.JHXW01000012_gene838	5.864e-33	133.0	COG0817@1|root,COG0817@2|Bacteria,37A4F@32066|Fusobacteria	32066|Fusobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DEZH2_k127_6293128_7	697303.Thewi_1151	2.426e-30	126.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,42EPZ@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DEZH2_k127_6293128_13	340099.Teth39_1000	1.622e-05	55.0	COG2385@1|root,COG3409@1|root,COG2385@2|Bacteria,COG3409@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,42FS4@68295|Thermoanaerobacterales	186801|Clostridia	D	Stage II sporulation D domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
DEZH2_k127_6316687_1	525255.HMPREF0077_0485	1.109e-93	323.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,22GGH@1570339|Peptoniphilaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
DEZH2_k127_6316687_0	626939.HMPREF9443_00952	2.674e-117	387.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4H1XS@909932|Negativicutes	909932|Negativicutes	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DEZH2_k127_6316687_2	546269.HMPREF0389_00586	6.131e-11	71.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
DEZH2_k127_6351126_14	1122611.KB903988_gene7173	3.835e-13	72.0	2EFVT@1|root,339N0@2|Bacteria,2GWUH@201174|Actinobacteria,4EKY7@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6351126_10	1123256.KB907925_gene1243	3.633e-20	98.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,1S6Y7@1236|Gammaproteobacteria,1X5Y5@135614|Xanthomonadales	135614|Xanthomonadales	C	Cytochrome B561	yodB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
DEZH2_k127_6351126_8	349521.HCH_04156	1.125e-24	108.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,1SFSE@1236|Gammaproteobacteria,1XM8D@135619|Oceanospirillales	135619|Oceanospirillales	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
DEZH2_k127_6351126_5	243164.DET1241	4.562e-63	221.0	COG0225@1|root,COG0225@2|Bacteria,2G6JK@200795|Chloroflexi,34DC5@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DEZH2_k127_6351126_16	1408473.JHXO01000007_gene811	1.041e-11	71.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes,2FSXA@200643|Bacteroidia	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
DEZH2_k127_6351126_0	1111732.AZOD01000019_gene502	1.677e-189	600.0	COG0446@1|root,COG0446@2|Bacteria,1QVWR@1224|Proteobacteria,1S0R6@1236|Gammaproteobacteria,1XC8R@135614|Xanthomonadales	135614|Xanthomonadales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
DEZH2_k127_6351126_13	756067.MicvaDRAFT_2242	3.702e-15	83.0	COG3290@1|root,COG4191@1|root,COG5000@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
DEZH2_k127_6351126_1	338969.Rfer_3391	2.463e-87	321.0	COG0834@1|root,COG2203@1|root,COG2206@1|root,COG0834@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,2W8ZE@28216|Betaproteobacteria,4AI3F@80864|Comamonadaceae	28216|Betaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
DEZH2_k127_6351126_6	1173024.KI912149_gene5192	8.78e-45	187.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
DEZH2_k127_6351126_7	316274.Haur_2143	1.463e-39	170.0	COG0784@1|root,COG1620@1|root,COG4251@1|root,COG0784@2|Bacteria,COG1620@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.1.1.80,3.1.1.61	ko:K03303,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	2.A.14	-	-	HATPase_c,HisKA,Lactate_perm,Response_reg
DEZH2_k127_6351126_12	304371.MCP_2581	1.299e-18	92.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,2NAXV@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DEZH2_k127_6351126_4	439235.Dalk_3496	6.439e-66	258.0	COG0834@1|root,COG2202@1|root,COG2203@1|root,COG3852@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3852@2|Bacteria,1NWNJ@1224|Proteobacteria,42NXV@68525|delta/epsilon subdivisions,2WUGY@28221|Deltaproteobacteria,2MPMJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	-
DEZH2_k127_6351126_2	580332.Slit_1327	8.944e-81	306.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria,44WPK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
DEZH2_k127_6351126_15	159450.NH14_08885	7.102e-12	69.0	2EGBE@1|root,33A39@2|Bacteria,1N3MX@1224|Proteobacteria,2W4FB@28216|Betaproteobacteria,1KAFZ@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6351126_11	1297863.APJF01000022_gene4612	1.167e-19	90.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,2UFDJ@28211|Alphaproteobacteria,3K17N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	PhnA domain	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
DEZH2_k127_6351126_3	1198452.Jab_2c26120	1.515e-79	277.0	COG2309@1|root,COG2309@2|Bacteria,1R4I5@1224|Proteobacteria,2VPND@28216|Betaproteobacteria,473BI@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6351126_9	234267.Acid_0055	8.866e-24	103.0	2AY4N@1|root,31Q6J@2|Bacteria,3Y7H6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6447125_3	714943.Mucpa_2562	2.647e-103	347.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IPZ9@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DEZH2_k127_6447125_7	742766.HMPREF9455_03939	6.495e-76	261.0	COG4912@1|root,COG4912@2|Bacteria,4NKBS@976|Bacteroidetes,2FM3U@200643|Bacteroidia,22XNZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DEZH2_k127_6447125_10	1123400.KB904791_gene136	1.147e-42	158.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
DEZH2_k127_6447125_0	1121949.AQXT01000002_gene1979	1.435e-180	577.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2TS4Z@28211|Alphaproteobacteria,43X51@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
DEZH2_k127_6447125_12	1173263.Syn7502_00507	4.234e-25	111.0	2DC00@1|root,2ZC4V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6447125_17	693746.OBV_10580	0.0007587	49.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,2N8YT@216572|Oscillospiraceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DEZH2_k127_6447125_15	1185876.BN8_05350	4.737e-10	64.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,47R3N@768503|Cytophagia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
DEZH2_k127_6447125_11	448385.sce2316	3.02e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,1RF2T@1224|Proteobacteria,42Y18@68525|delta/epsilon subdivisions,2WSRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DEZH2_k127_6447125_14	1123320.KB889702_gene9452	3.711e-17	86.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
DEZH2_k127_6447125_4	56780.SYN_00561	3.242e-97	332.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2MQEQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DEZH2_k127_6447125_6	196490.AUEZ01000055_gene235	2.503e-76	260.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,2U6KV@28211|Alphaproteobacteria,3JYM4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6447125_16	1031288.AXAA01000032_gene1208	2.013e-05	55.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.5.1.28,3.5.2.6	ko:K01448,ko:K17836	ko00311,ko01130,ko01501,ko01503,map00311,map01130,map01501,map01503	M00627,M00628,M00727	R04112,R06363	RC00064,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504,ko03036	-	-	-	Amidase_2,Amidase_3,Beta-lactamase2,DUF4280,LysM,PG_binding_1
DEZH2_k127_6447125_13	525904.Tter_0567	3.845e-21	104.0	COG3103@1|root,COG3764@1|root,COG3103@2|Bacteria,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	ylcC	-	3.4.22.70,3.5.1.104	ko:K07284,ko:K22278	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
DEZH2_k127_6447125_8	1321782.HMPREF1986_00949	4.713e-64	232.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,2PRUN@265975|Oribacterium	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DEZH2_k127_6447125_5	272952.HpaP806918	5.185e-83	287.0	COG0042@1|root,KOG2335@2759|Eukaryota,3QEGX@4776|Peronosporales	4776|Peronosporales	J	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	-	-	-	-	-	-	-	-	-	-	-	-	Dus
DEZH2_k127_6447125_2	1089548.KI783301_gene3209	2.705e-123	410.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3WDW8@539002|Bacillales incertae sedis	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DEZH2_k127_6447125_9	357808.RoseRS_4590	1.306e-55	205.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi,37541@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
DEZH2_k127_6447125_1	929704.Myrod_1318	2.046e-124	413.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,1HX5E@117743|Flavobacteriia,47H55@76831|Myroides	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
DEZH2_k127_6449848_2	880073.Calab_1738	0.0008741	42.0	COG0018@1|root,COG0018@2|Bacteria,2NNSE@2323|unclassified Bacteria	2|Bacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DEZH2_k127_6449848_1	1289135.A966_08749	5.569e-22	104.0	COG0563@1|root,COG0563@2|Bacteria,2J6MV@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
DEZH2_k127_6449848_0	240302.BN982_04022	4.933e-69	243.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3NDQ2@45667|Halobacillus	91061|Bacilli	E	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DEZH2_k127_6564988_12	471852.Tcur_2304	0.0002298	52.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,4EH9Q@85012|Streptosporangiales	201174|Actinobacteria	L	Protein of unknown function (DUF2800)	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
DEZH2_k127_6564988_7	1223410.KN050846_gene2851	3.572e-29	123.0	2C578@1|root,32RF7@2|Bacteria,4NS0I@976|Bacteroidetes,1I5AV@117743|Flavobacteriia	976|Bacteroidetes	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Gmad2
DEZH2_k127_6564988_1	224325.AF_0252	1.997e-163	531.0	COG0504@1|root,arCOG00063@2157|Archaea,2XTR2@28890|Euryarchaeota,245WV@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DEZH2_k127_6564988_6	742818.HMPREF9451_01081	2.88e-33	140.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CU8U@84998|Coriobacteriia	84998|Coriobacteriia	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
DEZH2_k127_6564988_3	1347392.CCEZ01000049_gene1653	1.444e-77	266.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,36DHJ@31979|Clostridiaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DEZH2_k127_6564988_4	311424.DhcVS_509	5.07e-72	254.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,34CN2@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DEZH2_k127_6564988_10	1296415.JACC01000022_gene4057	9.747e-05	47.0	2DRWY@1|root,33DG4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6564988_2	580327.Tthe_2088	6.767e-142	465.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DEZH2_k127_6564988_9	1033730.CAHG01000013_gene1284	1.608e-07	57.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4DRM4@85009|Propionibacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
DEZH2_k127_6564988_0	2325.TKV_c05890	7.292e-168	550.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,42F6C@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DEZH2_k127_6564988_16	1246995.AFR_05950	0.0009976	49.0	COG4966@1|root,COG4966@2|Bacteria,2GPVW@201174|Actinobacteria	201174|Actinobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DEZH2_k127_6564988_15	28229.ND2E_1079	0.0006819	50.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2Q756@267889|Colwelliaceae	1236|Gammaproteobacteria	NU	Pilin (bacterial filament)	ppdD	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650,ko:K02682	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
DEZH2_k127_6564988_5	349161.Dred_1047	2.939e-36	147.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,26256@186807|Peptococcaceae	186801|Clostridia	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
DEZH2_k127_6564988_14	426114.THI_0828	0.0005579	50.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,1KMKX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
DEZH2_k127_6564988_11	572544.Ilyop_0533	0.0001508	50.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	pilA	-	-	ko:K02650,ko:K02682	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
DEZH2_k127_6564988_13	411473.RUMCAL_02401	0.000539	43.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3WI9J@541000|Ruminococcaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DEZH2_k127_6614107_2	523794.Lebu_1977	1.538e-52	207.0	COG0018@1|root,COG0018@2|Bacteria,378C4@32066|Fusobacteria	32066|Fusobacteria	J	Psort location Cytoplasmic, score 9.97	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DEZH2_k127_6614107_4	1382306.JNIM01000001_gene2903	1.074e-33	139.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iNJ661.Rv3247c	Thymidylate_kin
DEZH2_k127_6614107_3	1121356.AQUW01000008_gene761	1.497e-36	143.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,22N78@1653|Corynebacteriaceae	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
DEZH2_k127_6614107_1	1485544.JQKP01000004_gene471	2.316e-93	324.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,44UYM@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
DEZH2_k127_6614107_0	580332.Slit_2520	3.922e-139	443.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,44VCH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DEZH2_k127_6723304_11	583355.Caka_1688	0.0007442	43.0	COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia,3K884@414999|Opitutae	414999|Opitutae	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DEZH2_k127_6723304_0	1158318.ATXC01000001_gene1271	1.82e-86	294.0	COG0090@1|root,COG0090@2|Bacteria,2G3KP@200783|Aquificae	200783|Aquificae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DEZH2_k127_6723304_9	1492738.FEM21_22210	2.332e-09	68.0	COG5295@1|root,COG5295@2|Bacteria,4PPSI@976|Bacteroidetes,1IKSS@117743|Flavobacteriia,2NYS8@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6723304_10	1499967.BAYZ01000016_gene6529	4.725e-08	64.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,Flg_new,SLH
DEZH2_k127_6723304_6	838561.P344_01700	4.027e-26	111.0	COG0185@1|root,COG0185@2|Bacteria,3WTPD@544448|Tenericutes	544448|Tenericutes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DEZH2_k127_6723304_7	1276229.SSYRP_v1c02200	2.708e-20	96.0	COG0091@1|root,COG0091@2|Bacteria,3WTMG@544448|Tenericutes	544448|Tenericutes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DEZH2_k127_6723304_1	765912.Thimo_2854	5.357e-51	189.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1WVYC@135613|Chromatiales	135613|Chromatiales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DEZH2_k127_6723304_3	688269.Theth_0737	9.513e-39	149.0	COG0197@1|root,COG0197@2|Bacteria,2GCXB@200918|Thermotogae	200918|Thermotogae	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DEZH2_k127_6723304_8	543913.D521_0061	8.274e-19	89.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DEZH2_k127_6723304_4	1051632.TPY_0333	1.25e-32	130.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3WCIH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DEZH2_k127_6723304_5	1157490.EL26_19210	3.093e-29	119.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,278I9@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DEZH2_k127_6723304_2	1304880.JAGB01000003_gene1198	7.222e-39	150.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DEZH2_k127_6973147_8	388739.RSK20926_02237	3.396e-13	74.0	COG1018@1|root,COG1018@2|Bacteria,1QUM3@1224|Proteobacteria	1224|Proteobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,FAD_binding_8,Ferric_reduct,NAD_binding_1
DEZH2_k127_6973147_4	858215.Thexy_0863	7.216e-52	209.0	COG5002@1|root,COG5002@2|Bacteria,1TQV5@1239|Firmicutes,248PK@186801|Clostridia,42J16@68295|Thermoanaerobacterales	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
DEZH2_k127_6973147_7	945713.IALB_2707	5.56e-16	81.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DEZH2_k127_6973147_9	635013.TherJR_1745	2.27e-08	66.0	COG4972@1|root,COG4972@2|Bacteria,1V19I@1239|Firmicutes,25DJ0@186801|Clostridia,2678V@186807|Peptococcaceae	186801|Clostridia	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DEZH2_k127_6973147_1	574087.Acear_0203	1.411e-73	269.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1TQJM@1239|Firmicutes,24CFC@186801|Clostridia	186801|Clostridia	C	TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
DEZH2_k127_6973147_3	572480.Arnit_0679	1.497e-70	247.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2YMMF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Abc transporter	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
DEZH2_k127_6973147_2	1231057.AMGD01000021_gene3173	1.121e-70	248.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,26DNV@186818|Planococcaceae	91061|Bacilli	P	COG1121 ABC-type Mn Zn transport systems, ATPase component	zurA	-	-	ko:K02074,ko:K09817	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
DEZH2_k127_6973147_0	349161.Dred_2645	1.589e-75	264.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,261H2@186807|Peptococcaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	iHN637.CLJU_RS18655	ZnuA
DEZH2_k127_6973147_6	926692.AZYG01000036_gene2487	5.258e-25	109.0	COG0735@1|root,COG0735@2|Bacteria,1VF38@1239|Firmicutes,24SA6@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K02076,ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DEZH2_k127_6973147_5	648996.Theam_1472	5.144e-38	149.0	COG0218@1|root,COG0218@2|Bacteria,2G471@200783|Aquificae	200783|Aquificae	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
DEZH2_k127_6985219_2	608538.HTH_1811	1.598e-122	404.0	COG2217@1|root,COG2217@2|Bacteria,2G4GR@200783|Aquificae	200783|Aquificae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
DEZH2_k127_6985219_11	1121895.Q765_03050	2.627e-09	70.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1HYKR@117743|Flavobacteriia,2NSV1@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
DEZH2_k127_6985219_4	661087.HMPREF1008_00152	7.238e-84	284.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4CV1R@84998|Coriobacteriia	84998|Coriobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DEZH2_k127_6985219_3	871968.DESME_13845	2.652e-109	366.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DEZH2_k127_6985219_10	1267533.KB906742_gene784	6.083e-15	91.0	COG2234@1|root,COG4932@1|root,COG5563@1|root,COG2234@2|Bacteria,COG4932@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	M	domain protein	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF1929,PA,Peptidase_M28
DEZH2_k127_6985219_8	84531.JMTZ01000015_gene2614	2.644e-20	109.0	2DQMZ@1|root,337PX@2|Bacteria,1P295@1224|Proteobacteria,1SSI6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_6985219_9	1492737.FEM08_20530	1.914e-17	100.0	COG1357@1|root,COG3656@1|root,COG1357@2|Bacteria,COG3656@2|Bacteria,4PNNZ@976|Bacteroidetes,1I4RS@117743|Flavobacteriia,2P0TF@237|Flavobacterium	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
DEZH2_k127_6985219_14	748727.CLJU_c25490	4.706e-05	59.0	COG2385@1|root,COG3409@1|root,COG2385@2|Bacteria,COG3409@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,36DFG@31979|Clostridiaceae	186801|Clostridia	D	TIGRFAM SpoIID LytB domain	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
DEZH2_k127_6985219_13	1122947.FR7_3381	1.168e-06	60.0	COG2165@1|root,COG2165@2|Bacteria,1VK8F@1239|Firmicutes,4H610@909932|Negativicutes	909932|Negativicutes	NU	Prepilin-type cleavage methylation N-terminal domain protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
DEZH2_k127_6985219_7	194439.CT0502	3.695e-30	127.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DEZH2_k127_6985219_12	109760.SPPG_02976T0	5.042e-09	64.0	COG0543@1|root,COG2041@1|root,COG5274@1|root,KOG0534@2759|Eukaryota,KOG0535@2759|Eukaryota,KOG0537@2759|Eukaryota,39MGM@33154|Opisthokonta,3P0PU@4751|Fungi	4751|Fungi	CH	Nitrate reductase	-	-	1.7.1.1,1.7.1.2,1.7.1.3	ko:K10534	ko00910,ko01120,map00910,map01120	M00531	R00794,R00796	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyt-b5,FAD_binding_6,Mo-co_dimer,NAD_binding_1,Oxidored_molyb
DEZH2_k127_6985219_5	1206730.BAGA01000181_gene2988	4.155e-83	282.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4FW5U@85025|Nocardiaceae	201174|Actinobacteria	S	VIT family	pcl	-	-	-	-	-	-	-	-	-	-	-	VIT1
DEZH2_k127_6985219_0	478741.JAFS01000001_gene1220	1.421e-296	937.0	COG0209@1|root,COG0209@2|Bacteria,46SFJ@74201|Verrucomicrobia,37H5M@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Ribonucleotide reductase, all-alpha domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
DEZH2_k127_6985219_1	1123368.AUIS01000003_gene1792	4.65e-128	417.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,2NBZD@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
DEZH2_k127_6985219_6	435590.BVU_3120	3.259e-54	200.0	2ARHX@1|root,31GUA@2|Bacteria,4PK5R@976|Bacteroidetes,2FU29@200643|Bacteroidia,4AVR9@815|Bacteroidaceae	976|Bacteroidetes	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
DEZH2_k127_7029637_4	386456.JQKN01000007_gene3270	1.783e-27	117.0	COG0537@1|root,arCOG00419@2157|Archaea	2157|Archaea	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
DEZH2_k127_7029637_2	1289135.A966_03383	1.106e-45	175.0	COG0617@1|root,COG0617@2|Bacteria,2J5ZC@203691|Spirochaetes	203691|Spirochaetes	H	PolyA polymerase	papS	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
DEZH2_k127_7029637_1	476272.RUMHYD_02046	8.141e-53	193.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3XZRW@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
DEZH2_k127_7029637_6	888727.HMPREF9092_1475	2.62e-11	71.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WDJ5@538999|Clostridiales incertae sedis	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DEZH2_k127_7029637_0	344747.PM8797T_03975	1.11e-70	251.0	COG0053@1|root,COG0053@2|Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	catA	-	-	ko:K14696	-	-	-	-	ko00000,ko02000	2.A.4.6	-	-	Cation_efflux,ZT_dimer
DEZH2_k127_7029637_3	909663.KI867150_gene877	1.381e-45	183.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43D5Y@68525|delta/epsilon subdivisions,2X8CR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DEZH2_k127_7029637_5	1238182.C882_0213	5.738e-23	104.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2JPZV@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DEZH2_k127_7029637_7	5334.XP_003027108.1	2.068e-09	59.0	COG3236@1|root,2S5B2@2759|Eukaryota,3A7P5@33154|Opisthokonta,3PE98@4751|Fungi,3VC74@5204|Basidiomycota,22BZA@155619|Agaricomycetes,3W9RG@5338|Agaricales	4751|Fungi	S	Domain of unknown function (DUF1768)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768
DEZH2_k127_7141106_7	1123250.KB908396_gene1837	2.728e-17	91.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,4H56P@909932|Negativicutes	909932|Negativicutes	S	Psort location Periplasmic, score	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
DEZH2_k127_7141106_2	1306947.ARQD01000005_gene49	3.184e-44	177.0	COG0166@1|root,COG0166@2|Bacteria,2NP2H@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iLJ478.TM1385	PGI
DEZH2_k127_7141106_4	998674.ATTE01000001_gene2897	3.444e-37	153.0	COG1651@1|root,COG1651@2|Bacteria,1RI8Q@1224|Proteobacteria,1SZ61@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
DEZH2_k127_7141106_8	313612.L8106_10727	2.431e-10	68.0	COG4243@1|root,COG4243@2|Bacteria,1FZWT@1117|Cyanobacteria,1H90D@1150|Oscillatoriales	1117|Cyanobacteria	CO	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
DEZH2_k127_7141106_1	751944.HALDL1_16645	8.279e-49	181.0	arCOG00346@1|root,arCOG00346@2157|Archaea,2XU0A@28890|Euryarchaeota,23V08@183963|Halobacteria	183963|Halobacteria	S	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
DEZH2_k127_7141106_9	198094.BA_1490	6.07e-08	65.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,1ZBRQ@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacB	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
DEZH2_k127_7141106_10	1273103.NM10_11372	1.401e-07	64.0	COG1376@1|root,COG1376@2|Bacteria,1TQAB@1239|Firmicutes,4H267@909932|Negativicutes	909932|Negativicutes	S	ErfK YbiS YcfS YnhG	erfK	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,YkuD
DEZH2_k127_7141106_3	264198.Reut_C6199	3.749e-42	166.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria,1K55Q@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
DEZH2_k127_7141106_0	509635.N824_14825	1.7e-65	229.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DEZH2_k127_7141106_6	876269.ARWA01000001_gene3676	1.358e-17	83.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,3NA4D@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
DEZH2_k127_7142715_2	1229276.DI53_2774	1.777e-06	56.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,1IS8A@117747|Sphingobacteriia	976|Bacteroidetes	K	(GNAT) family	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
DEZH2_k127_7142715_0	1322246.BN4_10929	5.354e-72	256.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria,2MGQJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DEZH2_k127_7142715_1	1408813.AYMG01000036_gene3303	1.993e-41	168.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,4NH18@976|Bacteroidetes,1IQRP@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
DEZH2_k127_7213631_4	158189.SpiBuddy_2837	4.754e-18	88.0	COG0199@1|root,COG0199@2|Bacteria,2J8U1@203691|Spirochaetes	203691|Spirochaetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DEZH2_k127_7213631_2	1403819.BATR01000164_gene5561	2.044e-32	130.0	COG0096@1|root,COG0096@2|Bacteria,46T2K@74201|Verrucomicrobia,2IUCT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DEZH2_k127_7213631_0	525379.HMPREF0819_1726	1.197e-44	168.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DEZH2_k127_7213631_1	1158318.ATXC01000001_gene1258	2.828e-33	132.0	COG0256@1|root,COG0256@2|Bacteria,2G476@200783|Aquificae	200783|Aquificae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
DEZH2_k127_7213631_3	388467.A19Y_0436	3.471e-31	132.0	COG0098@1|root,COG0098@2|Bacteria,1G1EF@1117|Cyanobacteria,1H7SH@1150|Oscillatoriales	1117|Cyanobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rps5	GO:0003674,GO:0003735,GO:0005198,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DEZH2_k127_7213631_5	862517.HMPREF9225_0157	1.708e-10	67.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,22HCT@1570339|Peptoniphilaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DEZH2_k127_726509_0	1449126.JQKL01000001_gene1375	8.059e-26	115.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,268A5@186813|unclassified Clostridiales	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DEZH2_k127_728504_0	760142.Hipma_0827	5.78e-160	518.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DEZH2_k127_728504_2	1347086.CCBA010000012_gene2033	9.016e-05	44.0	2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli,1ZJ7K@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_728504_1	373903.Hore_03220	1.338e-129	429.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WABC@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
DEZH2_k127_7323188_0	1397696.KK211189_gene2744	2.679e-120	404.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3WEIR@539002|Bacillales incertae sedis	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DEZH2_k127_7323188_1	255470.cbdbA355	2.335e-55	203.0	COG0030@1|root,COG0030@2|Bacteria,2G6ER@200795|Chloroflexi,34CIF@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DEZH2_k127_7351575_1	768671.ThimaDRAFT_4485	1.252e-17	98.0	COG0265@1|root,COG1075@1|root,COG2304@1|root,COG0265@2|Bacteria,COG1075@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	MA20_07505	-	1.1.3.6,1.6.5.3,3.4.21.107	ko:K00337,ko:K03333,ko:K04771,ko:K07114	ko00190,ko00984,ko01100,ko01120,ko01503,ko02020,map00190,map00984,map01100,map01120,map01503,map02020	M00144,M00728	R01459,R11945	RC00061,RC00146	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03110	1.A.13.2.2,1.A.13.2.3,3.D.1	-	-	DUF1194
DEZH2_k127_7351575_0	1123393.KB891326_gene94	0.0	1328.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,1KSK1@119069|Hydrogenophilales	119069|Hydrogenophilales	G	XFP C-terminal domain	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
DEZH2_k127_7377122_1	379066.GAU_2568	3.198e-34	143.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DEZH2_k127_7377122_0	1444309.JAQG01000172_gene456	1.335e-103	347.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,26QNT@186822|Paenibacillaceae	91061|Bacilli	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DEZH2_k127_7377122_2	1500281.JQKZ01000032_gene305	6.903e-17	85.0	COG0745@1|root,COG0745@2|Bacteria,4NP5C@976|Bacteroidetes,1I24M@117743|Flavobacteriia,3ZRYE@59732|Chryseobacterium	976|Bacteroidetes	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DEZH2_k127_7440771_2	1323361.JPOC01000057_gene3183	8.585e-08	54.0	COG0488@1|root,COG0488@2|Bacteria,2GJHN@201174|Actinobacteria,4FU2X@85025|Nocardiaceae	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DEZH2_k127_7440771_0	1122179.KB890435_gene893	6.907e-91	318.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1INY6@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DEZH2_k127_7440771_1	1089548.KI783301_gene4	1.181e-12	74.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,3WFJ8@539002|Bacillales incertae sedis	91061|Bacilli	K	Sigma-70 region 2	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DEZH2_k127_7440771_4	96561.Dole_1787	1.194e-05	57.0	COG1653@1|root,COG3210@1|root,COG3266@1|root,COG5492@1|root,COG1653@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG5492@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7490109_10	1123372.AUIT01000002_gene174	2.486e-08	56.0	COG0566@1|root,COG0566@2|Bacteria,2GHKT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
DEZH2_k127_7490109_6	485913.Krac_8498	1.77e-38	154.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DEZH2_k127_7490109_8	926550.CLDAP_05100	1.508e-20	93.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DEZH2_k127_7490109_12	1178537.BA1_01440	0.0009685	48.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
DEZH2_k127_7490109_11	1128398.Curi_c02020	0.0005251	48.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,269VJ@186813|unclassified Clostridiales	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DEZH2_k127_7490109_1	204536.SULAZ_0458	1.218e-176	567.0	COG0056@1|root,COG0056@2|Bacteria,2G3IZ@200783|Aquificae	200783|Aquificae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DEZH2_k127_7490109_3	1449126.JQKL01000005_gene874	1.68e-58	214.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,268Q6@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DEZH2_k127_7490109_0	598659.NAMH_0322	4.178e-198	627.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2YMA9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DEZH2_k127_7490109_9	431943.CKL_3687	6.493e-10	63.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,36MZ0@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
DEZH2_k127_7490109_2	5691.AAZ11241	3.994e-64	240.0	COG0659@1|root,KOG0236@2759|Eukaryota	2759|Eukaryota	U	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
DEZH2_k127_7490109_5	186497.PF1385	9.271e-53	192.0	COG1573@1|root,arCOG00905@2157|Archaea,2XUVI@28890|Euryarchaeota,243FM@183968|Thermococci	183968|Thermococci	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DEZH2_k127_7490109_4	1437425.CSEC_0539	1.852e-55	204.0	COG0500@1|root,COG2226@2|Bacteria,2JHHE@204428|Chlamydiae	204428|Chlamydiae	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DEZH2_k127_7490109_7	1896.JOAU01000012_gene741	9.808e-22	107.0	COG1595@1|root,COG2340@1|root,COG1595@2|Bacteria,COG2340@2|Bacteria,2GJ21@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Sigma70_r2
DEZH2_k127_7490440_2	926569.ANT_13970	5.028e-56	208.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DEZH2_k127_7490440_0	273068.TTE1195	1.791e-135	449.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,42F3U@68295|Thermoanaerobacterales	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
DEZH2_k127_7490440_1	1026882.MAMP_00781	3.251e-78	274.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales	72273|Thiotrichales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
DEZH2_k127_7495079_0	1280689.AUJC01000004_gene392	3.51e-39	167.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,36DH7@31979|Clostridiaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DEZH2_k127_7834955_8	420890.LCGL_0919	6.436e-32	130.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,1YBSF@1357|Lactococcus	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DEZH2_k127_7834955_13	525919.Apre_1145	4.626e-13	77.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,22HI4@1570339|Peptoniphilaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DEZH2_k127_7834955_9	313612.L8106_14590	2.003e-29	138.0	COG2730@1|root,COG2931@1|root,COG3386@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
DEZH2_k127_7834955_14	1235457.C404_24200	5.2e-10	74.0	COG4676@1|root,COG4676@2|Bacteria,1R84A@1224|Proteobacteria,2VY7J@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7834955_15	40373.F991_01763	2.21e-06	58.0	2C7B9@1|root,33CKJ@2|Bacteria,1NPF9@1224|Proteobacteria,1STH6@1236|Gammaproteobacteria,3NQBZ@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7834955_11	760142.Hipma_1720	6.97e-24	109.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DEZH2_k127_7834955_3	1121396.KB893072_gene1230	7.956e-116	402.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DEZH2_k127_7834955_1	2325.TKV_c12920	2.522e-133	432.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,42F99@68295|Thermoanaerobacterales	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DEZH2_k127_7834955_7	246194.CHY_1872	3.913e-35	141.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,42FJ9@68295|Thermoanaerobacterales	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DEZH2_k127_7834955_12	679192.HMPREF9013_0960	5.775e-15	81.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,3VRD8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DEZH2_k127_7834955_6	1163617.SCD_n00654	3.884e-35	139.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DEZH2_k127_7834955_16	452471.Aasi_0399	0.0002588	50.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DEZH2_k127_7834955_5	457570.Nther_0044	4.791e-46	176.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DEZH2_k127_7834955_2	525904.Tter_0176	1.071e-120	406.0	COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DEZH2_k127_7834955_10	1121272.KB903249_gene1253	2.369e-26	121.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4DAVA@85008|Micromonosporales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DEZH2_k127_7834955_4	871968.DESME_11225	6.266e-72	259.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DEZH2_k127_7834955_0	479434.Sthe_0466	8.331e-150	487.0	COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,27XGU@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of glycine to tRNA(Gly)	-	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DEZH2_k127_7895495_4	985255.APHJ01000021_gene1648	7.319e-06	55.0	2EHX5@1|root,3385X@2|Bacteria,4NVDX@976|Bacteroidetes,1I67H@117743|Flavobacteriia,2P72J@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_7895495_2	1283283.ATXA01000018_gene4171	2.151e-24	114.0	COG1749@1|root,COG3386@1|root,COG4932@1|root,COG1749@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales	201174|Actinobacteria	N	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,Mo-co_dimer,fn3
DEZH2_k127_7895495_1	1547445.LO80_00885	1.887e-32	136.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,463R3@72273|Thiotrichales	72273|Thiotrichales	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DEZH2_k127_7895495_0	234267.Acid_0055	2.003e-39	152.0	2AY4N@1|root,31Q6J@2|Bacteria,3Y7H6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_820005_0	1042163.BRLA_c025470	4.872e-222	702.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,26SQA@186822|Paenibacillaceae	91061|Bacilli	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DEZH2_k127_820005_2	1232666.JANE01000028_gene893	1.472e-44	171.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,4GY2U@90964|Staphylococcaceae	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DEZH2_k127_820005_1	670307.HYPDE_26713	6.389e-174	558.0	COG1075@1|root,COG1075@2|Bacteria,1NMH0@1224|Proteobacteria,2TXVV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
DEZH2_k127_820005_3	679926.Mpet_2786	5.414e-21	96.0	COG2703@1|root,arCOG06577@2157|Archaea,2Y1Y0@28890|Euryarchaeota,2NB26@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
DEZH2_k127_820005_4	1280668.ATVT01000011_gene3365	6.705e-09	57.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,4BZZB@830|Butyrivibrio	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DEZH2_k127_827513_1	1051632.TPY_0308	6.06e-55	205.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DEZH2_k127_827513_0	593750.Metfor_2226	9.283e-96	323.0	COG2899@1|root,arCOG05299@2157|Archaea,2Y4HF@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF475)	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
DEZH2_k127_827513_2	1008459.TASI_0821	1.057e-39	160.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,3T295@506|Alcaligenaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DEZH2_k127_827513_3	1380600.AUYN01000009_gene1025	1.324e-33	134.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia	976|Bacteroidetes	J	Methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
DEZH2_k127_8279297_8	156889.Mmc1_1955	5.282e-07	62.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	MA20_30780	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DEZH2_k127_8279297_5	626887.J057_00599	1.072e-12	76.0	COG4469@1|root,COG4469@2|Bacteria	2|Bacteria	-	-	coiA	-	3.6.4.12	ko:K03657,ko:K06198	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CoiA
DEZH2_k127_8279297_0	56780.SYN_00497	0.0	1247.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DEZH2_k127_8279297_6	1349820.M707_22790	9.396e-10	67.0	29T71@1|root,30EDT@2|Bacteria,2IGIA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8279297_2	326298.Suden_0945	4.79e-98	335.0	COG1746@1|root,COG1746@2|Bacteria,1NVSS@1224|Proteobacteria	1224|Proteobacteria	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
DEZH2_k127_8279297_10	471870.BACINT_04003	0.0002737	51.0	2E7MJ@1|root,3323D@2|Bacteria,4NYZJ@976|Bacteroidetes,2FXPJ@200643|Bacteroidia	976|Bacteroidetes	S	Abortive infection C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Abi_C
DEZH2_k127_8279297_3	56780.SYN_00495	7.154e-75	268.0	COG0732@1|root,COG0732@2|Bacteria,1MXSQ@1224|Proteobacteria,42UA8@68525|delta/epsilon subdivisions,2X5HA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
DEZH2_k127_8279297_4	1487923.DP73_15840	1.743e-59	220.0	COG3093@1|root,COG3093@2|Bacteria,1V0AU@1239|Firmicutes,24BH5@186801|Clostridia	186801|Clostridia	K	Addiction module antidote protein, HigA	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
DEZH2_k127_8279297_9	373903.Hore_20200	0.0001677	48.0	COG3549@1|root,COG3549@2|Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
DEZH2_k127_8279297_1	56780.SYN_00494	8.016e-272	842.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42N9K@68525|delta/epsilon subdivisions,2WINH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
DEZH2_k127_8279297_7	1121287.AUMU01000015_gene254	1.277e-09	61.0	COG1476@1|root,COG1476@2|Bacteria,4NVQ6@976|Bacteroidetes,1I51D@117743|Flavobacteriia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DEZH2_k127_8358903_15	396513.SCA_0894	6.995e-25	109.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,4GXQG@90964|Staphylococcaceae	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DEZH2_k127_8358903_8	1449126.JQKL01000001_gene1368	2.758e-55	207.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,267S9@186813|unclassified Clostridiales	186801|Clostridia	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
DEZH2_k127_8358903_21	339670.Bamb_1120	1.048e-11	72.0	2CJRU@1|root,3388F@2|Bacteria,1N9P3@1224|Proteobacteria,2W3MD@28216|Betaproteobacteria,1KIB3@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8358903_20	1005048.CFU_3278	6.569e-12	76.0	2CJRU@1|root,3388F@2|Bacteria,1N9P3@1224|Proteobacteria,2W3MD@28216|Betaproteobacteria,478V4@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8358903_2	1541960.KQ78_00792	1.51e-110	372.0	COG0442@1|root,COG0442@2|Bacteria,3WV4I@544448|Tenericutes	544448|Tenericutes	J	Anticodon binding domain	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
DEZH2_k127_8358903_1	935948.KE386494_gene53	3.906e-116	383.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,42EXB@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DEZH2_k127_8358903_27	1122137.AQXF01000003_gene2471	0.0004651	51.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DEZH2_k127_8358903_6	744872.Spica_1386	2.564e-68	254.0	COG0768@1|root,COG0768@2|Bacteria,2J595@203691|Spirochaetes	203691|Spirochaetes	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
DEZH2_k127_8358903_13	864565.HMPREF0379_1366	2.982e-31	128.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,25RD0@186804|Peptostreptococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DEZH2_k127_8358903_0	555079.Toce_0164	3.95e-131	434.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
DEZH2_k127_8358903_9	879308.HMPREF9130_1572	1.554e-41	157.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,22HDJ@1570339|Peptoniphilaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
DEZH2_k127_8358903_5	608538.HTH_0955	2.581e-69	245.0	COG0275@1|root,COG0275@2|Bacteria,2G3T6@200783|Aquificae	200783|Aquificae	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
DEZH2_k127_8358903_3	525904.Tter_1614	5.696e-84	300.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
DEZH2_k127_8358903_10	701521.PECL_226	5.693e-41	164.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_8358903_22	1121430.JMLG01000003_gene623	2.416e-11	67.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_8358903_14	1304865.JAGF01000001_gene2536	4.777e-28	125.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,2IETB@201174|Actinobacteria	201174|Actinobacteria	P	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
DEZH2_k127_8358903_19	1122138.AQUZ01000008_gene3634	2.646e-14	78.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria,2IETB@201174|Actinobacteria	201174|Actinobacteria	P	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
DEZH2_k127_8358903_4	525898.Sdel_1531	6.746e-81	276.0	28IMK@1|root,2Z8N2@2|Bacteria,1R85A@1224|Proteobacteria	1224|Proteobacteria	L	Dam-replacing family	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DpnI
DEZH2_k127_8358903_26	87626.PTD2_18180	0.0003865	49.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,1S47Z@1236|Gammaproteobacteria,2Q1ZM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
DEZH2_k127_8358903_12	1410632.JHWW01000005_gene733	2.512e-32	133.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,27MZJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
DEZH2_k127_8358903_7	493475.GARC_2376	1.003e-58	215.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	META
DEZH2_k127_8358903_23	525904.Tter_1728	7.846e-09	63.0	2E36Z@1|root,30JET@2|Bacteria,2NS38@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8358903_11	748727.CLJU_c21640	1.785e-32	135.0	COG0560@1|root,COG0560@2|Bacteria,1V4PY@1239|Firmicutes,25CGU@186801|Clostridia,36WVR@31979|Clostridiaceae	186801|Clostridia	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
DEZH2_k127_8358903_16	2340.JV46_13660	8.377e-24	112.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1J5P6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DEZH2_k127_8358903_18	1172180.KB911775_gene6199	7.695e-17	94.0	COG3976@1|root,COG3976@2|Bacteria,2INK5@201174|Actinobacteria	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
DEZH2_k127_8358903_24	543632.JOJL01000027_gene2917	8.697e-07	62.0	COG3976@1|root,COG3976@2|Bacteria,2GTTI@201174|Actinobacteria,4DG77@85008|Micromonosporales	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
DEZH2_k127_8358903_25	1120946.AUBF01000004_gene1624	1.204e-06	58.0	COG3976@1|root,COG3976@2|Bacteria,2HQX4@201174|Actinobacteria,4D7T0@85005|Actinomycetales	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
DEZH2_k127_8358903_17	511.JT27_06255	2.56e-20	101.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,2VMHN@28216|Betaproteobacteria,3T381@506|Alcaligenaceae	28216|Betaproteobacteria	C	COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
DEZH2_k127_836366_0	373903.Hore_05970	3.148e-112	383.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WAAY@53433|Halanaerobiales	186801|Clostridia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DEZH2_k127_8392855_0	941449.dsx2_2171	3.955e-94	317.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42P0J@68525|delta/epsilon subdivisions,2WJJQ@28221|Deltaproteobacteria,2M8T4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
DEZH2_k127_8392855_1	1485545.JQLW01000001_gene1406	1.927e-32	133.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria	1224|Proteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DEZH2_k127_8392855_2	5833.PFI0375w	0.0002115	47.0	2D5DK@1|root,2SY67@2759|Eukaryota,3YCIT@5794|Apicomplexa,3KBFH@422676|Aconoidasida,3Z095@5819|Haemosporida	422676|Aconoidasida	G	Belongs to the bacterial ribosomal protein bL35 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L35p
DEZH2_k127_8420873_4	1499967.BAYZ01000076_gene830	6.578e-43	165.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
DEZH2_k127_8420873_7	312284.A20C1_01196	1.14e-06	59.0	292NE@1|root,2ZQ69@2|Bacteria,2IKBG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8420873_2	1134413.ANNK01000111_gene1591	1.971e-105	357.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,1ZAV8@1386|Bacillus	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DEZH2_k127_8420873_3	1433126.BN938_1578	1.16e-93	328.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,2FMV1@200643|Bacteroidia,22U3Z@171550|Rikenellaceae	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
DEZH2_k127_8420873_0	720554.Clocl_0656	0.0	1108.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DEZH2_k127_8420873_1	1304875.JAFZ01000002_gene165	0.0	1060.0	COG0085@1|root,COG0085@2|Bacteria,3TA41@508458|Synergistetes	508458|Synergistetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DEZH2_k127_8420873_5	693661.Arcve_0646	2.166e-42	159.0	arCOG06733@1|root,arCOG06733@2157|Archaea,2Y62E@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8420873_6	1219077.VAZ01S_079_00150	9.395e-30	123.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XSG2@135623|Vibrionales	135623|Vibrionales	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DEZH2_k127_8447191_8	350688.Clos_1587	2.931e-17	86.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,36EKU@31979|Clostridiaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
DEZH2_k127_8447191_1	1128421.JAGA01000004_gene2572	1.092e-118	396.0	COG0173@1|root,COG0173@2|Bacteria,2NNP3@2323|unclassified Bacteria	2|Bacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DEZH2_k127_8447191_2	888055.HMPREF9015_00184	3.684e-98	330.0	COG0180@1|root,COG0180@2|Bacteria,37854@32066|Fusobacteria	32066|Fusobacteria	J	Psort location Cytoplasmic, score	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DEZH2_k127_8447191_4	383372.Rcas_1113	1.748e-37	160.0	COG2202@1|root,COG2203@1|root,COG3290@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,2GBK6@200795|Chloroflexi,3770Y@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA,PAS_9,Response_reg
DEZH2_k127_8447191_5	1157943.KB892705_gene706	3.046e-29	134.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,235P5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DEZH2_k127_8447191_6	330214.NIDE0964	3.05e-27	128.0	COG0642@1|root,COG2205@2|Bacteria	330214.NIDE0964|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8447191_9	110662.Syncc9605_2510	4.128e-13	79.0	COG0664@1|root,COG0664@2|Bacteria,1GC7M@1117|Cyanobacteria,1H02U@1129|Synechococcus	1117|Cyanobacteria	T	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20,cNMP_binding
DEZH2_k127_8447191_3	1121423.JONT01000001_gene1966	3.048e-90	310.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DEZH2_k127_8447191_0	1382306.JNIM01000001_gene1384	4.57e-234	739.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DEZH2_k127_8447191_7	580327.Tthe_1184	8.121e-25	113.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DEZH2_k127_8447191_10	1207063.P24_10785	9.392e-06	54.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria,2JQQ5@204441|Rhodospirillales	204441|Rhodospirillales	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
DEZH2_k127_8452968_0	1123377.AUIV01000013_gene2380	5.224e-113	378.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1S1ID@1236|Gammaproteobacteria,1X5P0@135614|Xanthomonadales	135614|Xanthomonadales	P	E1-E2 ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
DEZH2_k127_8452968_1	1121448.DGI_1474	1.109e-12	73.0	COG5483@1|root,COG5483@2|Bacteria,1RFEQ@1224|Proteobacteria,430D0@68525|delta/epsilon subdivisions,2WVZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DEZH2_k127_8480890_0	1408439.JHXW01000009_gene343	9.285e-67	234.0	COG0313@1|root,COG0313@2|Bacteria,378EN@32066|Fusobacteria	32066|Fusobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DEZH2_k127_8480890_1	292459.STH1268	3.584e-66	241.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
DEZH2_k127_8501363_1	883.DvMF_2623	1.134e-21	99.0	COG0607@1|root,COG0607@2|Bacteria,1Q5KY@1224|Proteobacteria,42WYK@68525|delta/epsilon subdivisions,2WQQW@28221|Deltaproteobacteria,2MDQK@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DEZH2_k127_8501363_2	661478.OP10G_3427	5.991e-07	61.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,T2SSG
DEZH2_k127_8501363_0	335543.Sfum_0670	2.115e-31	144.0	COG4447@1|root,COG4447@2|Bacteria,1PFB5@1224|Proteobacteria,437G8@68525|delta/epsilon subdivisions,2X2NT@28221|Deltaproteobacteria,2MRPS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8513254_2	1121870.AUAA01000078_gene1196	7.456e-09	57.0	2DMHR@1|root,32RMI@2|Bacteria,4NUR9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8513254_0	706587.Desti_3853	5.381e-98	336.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MQ6S@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
DEZH2_k127_8513254_1	591001.Acfer_1301	6.561e-95	326.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4H1VH@909932|Negativicutes	909932|Negativicutes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
DEZH2_k127_8642128_1	944479.JQLX01000005_gene1719	1.827e-10	63.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DEZH2_k127_8642128_2	1268237.G114_05840	4.294e-05	54.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1Y4SI@135624|Aeromonadales	135624|Aeromonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
DEZH2_k127_8642128_0	431943.CKL_1113	3.508e-20	99.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,36DG2@31979|Clostridiaceae	186801|Clostridia	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
DEZH2_k127_8677325_3	663321.REG_0074	1.737e-59	213.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,282JU@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
DEZH2_k127_8677325_0	1227349.C170_05338	1.365e-119	400.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,26R27@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
DEZH2_k127_8677325_1	1051632.TPY_0657	5.008e-78	272.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WCE5@538999|Clostridiales incertae sedis	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
DEZH2_k127_8677325_2	400668.Mmwyl1_2741	1.828e-67	240.0	COG4286@1|root,COG4286@2|Bacteria,1MVTY@1224|Proteobacteria,1RYWZ@1236|Gammaproteobacteria,1XIQC@135619|Oceanospirillales	135619|Oceanospirillales	S	metal-dependent protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
DEZH2_k127_8677325_6	1385420.FRA_34c06000	5.911e-07	59.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1SDU8@1236|Gammaproteobacteria,460WH@72273|Thiotrichales	72273|Thiotrichales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DEZH2_k127_8677325_5	1329516.JPST01000008_gene1984	2.437e-21	97.0	COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,27CBH@186824|Thermoactinomycetaceae	91061|Bacilli	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DEZH2_k127_8677325_4	941449.dsx2_2274	1.886e-36	141.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,42R07@68525|delta/epsilon subdivisions,2X5GE@28221|Deltaproteobacteria,2MGQK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DEZH2_k127_8974382_2	1121428.DESHY_40188___1	4.777e-121	398.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,260A4@186807|Peptococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
DEZH2_k127_8974382_9	479434.Sthe_2034	6.922e-08	59.0	COG4243@1|root,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,27YHV@189775|Thermomicrobia	189775|Thermomicrobia	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
DEZH2_k127_8974382_7	1408424.JHYI01000036_gene2533	1.898e-23	111.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	yodJ	-	3.4.16.4,3.4.17.14	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	PG_binding_1,VanY
DEZH2_k127_8974382_0	926561.KB900623_gene719	8.565e-146	488.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WA9E@53433|Halanaerobiales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DEZH2_k127_8974382_1	926549.KI421517_gene624	9.876e-134	450.0	COG0339@1|root,COG0339@2|Bacteria,4NJKN@976|Bacteroidetes,47KKE@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M3	-	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
DEZH2_k127_8974382_8	588581.Cpap_3660	3.341e-15	83.0	COG0558@1|root,COG0558@2|Bacteria,1V35A@1239|Firmicutes,24IIY@186801|Clostridia,3WJ97@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DEZH2_k127_8974382_4	395494.Galf_0847	2.017e-61	222.0	2E54J@1|root,32ZXH@2|Bacteria,1R9DG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8974382_6	552811.Dehly_1715	1.826e-24	114.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,34CXG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_8974382_5	1540221.JQNI01000002_gene1751	2.938e-29	130.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DEZH2_k127_8982943_3	1408254.T458_07050	1.262e-54	200.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,26TDJ@186822|Paenibacillaceae	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
DEZH2_k127_8982943_0	237368.SCABRO_02504	3.21e-104	351.0	COG0126@1|root,COG0126@2|Bacteria,2IYIS@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DEZH2_k127_8982943_2	1122176.KB903544_gene780	2.771e-75	268.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1INXG@117747|Sphingobacteriia	976|Bacteroidetes	EGP	major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
DEZH2_k127_8982943_6	453591.Igni_1099	6.013e-38	149.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQZ7@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DEZH2_k127_8982943_1	1236976.JCM16418_740	1.277e-95	333.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26QNN@186822|Paenibacillaceae	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
DEZH2_k127_8982943_4	1242864.D187_005486	2.588e-53	196.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2WPJY@28221|Deltaproteobacteria,2YW6H@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
DEZH2_k127_8982943_5	243164.DET0024	5.99e-44	179.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi,34CYA@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF4131)	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
DEZH2_k127_8982943_7	556267.HWAG_01028	7.785e-09	61.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RMJ@68525|delta/epsilon subdivisions,2YMZV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DEZH2_k127_8990209_1	85643.Tmz1t_2649	3.129e-21	97.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KWBT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DEZH2_k127_8990209_0	261292.Nit79A3_0857	1.235e-36	145.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJGY@28216|Betaproteobacteria,372VE@32003|Nitrosomonadales	28216|Betaproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_9,TarH
DEZH2_k127_8990209_2	388739.RSK20926_02237	8.114e-09	61.0	COG1018@1|root,COG1018@2|Bacteria,1QUM3@1224|Proteobacteria	1224|Proteobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,FAD_binding_8,Ferric_reduct,NAD_binding_1
DEZH2_k127_9020726_3	1547437.LL06_16350	2.96e-16	87.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,43JF1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
DEZH2_k127_9020726_0	309807.SRU_1720	1.046e-74	258.0	COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1FK37@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DEZH2_k127_9020726_1	456442.Mboo_1496	1.239e-56	220.0	COG3920@1|root,arCOG02330@1|root,arCOG02350@1|root,arCOG02330@2157|Archaea,arCOG02335@2157|Archaea,arCOG02350@2157|Archaea	2157|Archaea	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DEZH2_k127_9020726_2	1157943.KB892705_gene706	6.979e-32	143.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,235P5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DEZH2_k127_9020726_4	97138.C820_02498	1.102e-05	51.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,36JIC@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	cadC	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
DEZH2_k127_9039231_2	1121019.AUMN01000007_gene2513	3.64e-72	248.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,1W82N@1268|Micrococcaceae	201174|Actinobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DEZH2_k127_9039231_1	1303518.CCALI_00921	2.462e-233	740.0	COG0556@1|root,COG0556@2|Bacteria	2|Bacteria	L	nucleotide-excision repair	uvrB	-	-	ko:K03702,ko:K08999	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DEZH2_k127_9039231_10	1232683.ADIMK_2329	0.0006641	50.0	COG3637@1|root,COG3637@2|Bacteria,1PH1C@1224|Proteobacteria,1SHSJ@1236|Gammaproteobacteria,46980@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DEZH2_k127_9039231_0	1449126.JQKL01000003_gene1745	2.463e-296	932.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,267M9@186813|unclassified Clostridiales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DEZH2_k127_9039231_3	97138.C820_00650	7.697e-60	222.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,36DMH@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DEZH2_k127_9039231_9	1122599.AUGR01000001_gene382	0.000233	51.0	2AIE8@1|root,318VP@2|Bacteria,1N3HJ@1224|Proteobacteria,1SB1R@1236|Gammaproteobacteria,1XM7K@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_9039231_8	1347342.BN863_17880	5.342e-11	68.0	2ESXY@1|root,33KG8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_9039231_6	91464.S7335_2911	5.366e-27	116.0	COG1610@1|root,COG1610@2|Bacteria,1G607@1117|Cyanobacteria,1H38P@1129|Synechococcus	1117|Cyanobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
DEZH2_k127_9039231_7	323848.Nmul_A1501	5.151e-21	100.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VV19@28216|Betaproteobacteria,374K7@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Protoglobin	-	-	2.7.7.65	ko:K13590,ko:K21019	ko02025,ko04112,map02025,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Protoglobin
DEZH2_k127_9039231_4	1047013.AQSP01000140_gene2513	1.606e-38	158.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
DEZH2_k127_9039231_5	357809.Cphy_2551	1.58e-27	114.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,220E7@1506553|Lachnoclostridium	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
DEZH2_k127_9414777_5	933115.GPDM_02740	1.375e-08	68.0	COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4HA2V@91061|Bacilli,26CXW@186818|Planococcaceae	91061|Bacilli	M	Cell Wall Hydrolase	sleB	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,PG_binding_1
DEZH2_k127_9414777_2	926550.CLDAP_10900	2.761e-24	113.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
DEZH2_k127_9414777_6	1234679.BN424_1739	0.0001485	52.0	COG4990@1|root,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HJBT@91061|Bacilli	91061|Bacilli	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
DEZH2_k127_9414777_1	1123508.JH636448_gene7526	5.53e-29	124.0	COG0434@1|root,COG0434@2|Bacteria	2|Bacteria	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
DEZH2_k127_9414777_0	523845.AQXV01000049_gene958	4.857e-57	209.0	COG4902@1|root,arCOG03957@2157|Archaea,2XX05@28890|Euryarchaeota,23QWG@183939|Methanococci	183939|Methanococci	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
DEZH2_k127_9414777_4	1121920.AUAU01000013_gene1722	5.835e-14	79.0	2CCI4@1|root,30BPJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_9414777_3	1294142.CINTURNW_3018	1.217e-17	91.0	COG0551@1|root,COG1787@1|root,COG0551@2|Bacteria,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,36MS5@31979|Clostridiaceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
DEZH2_k127_941597_3	1123388.AQWU01000071_gene38	4.725e-63	226.0	COG1189@1|root,COG1189@2|Bacteria,1WJ23@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	TIGRFAM hemolysin TlyA family protein	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
DEZH2_k127_941597_8	86106.I862_02480	1.181e-13	77.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,47FHR@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
DEZH2_k127_941597_0	1168289.AJKI01000063_gene3511	1.165e-179	585.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,2FMM6@200643|Bacteroidia,3XIQP@558415|Marinilabiliaceae	976|Bacteroidetes	K	RNB	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
DEZH2_k127_941597_6	1125712.HMPREF1316_1759	5.643e-25	112.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CVKY@84998|Coriobacteriia	84998|Coriobacteriia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
DEZH2_k127_941597_7	3694.POPTR_0006s23300.1	7.123e-24	108.0	28N75@1|root,2QUSF@2759|Eukaryota,37HS3@33090|Viridiplantae,3G9DW@35493|Streptophyta,4JG68@91835|fabids	35493|Streptophyta	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
DEZH2_k127_941597_10	519989.ECTPHS_09532	4.384e-06	54.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria	1224|Proteobacteria	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	MA20_21960	-	-	-	-	-	-	-	-	-	-	-	HIT
DEZH2_k127_941597_2	889378.Spiaf_1207	1.734e-73	274.0	COG1196@1|root,COG1196@2|Bacteria,2J57J@203691|Spirochaetes	203691|Spirochaetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
DEZH2_k127_941597_4	485913.Krac_10919	6.471e-55	200.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DEZH2_k127_941597_9	1341151.ASZU01000004_gene381	1.266e-07	63.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli,27C00@186824|Thermoactinomycetaceae	91061|Bacilli	F	NUDIX domain	apfA	-	3.6.1.61	ko:K18445	ko00230,map00230	-	R00184	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
DEZH2_k127_941597_5	644966.Tmar_1173	4.271e-27	122.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3WDJZ@538999|Clostridiales incertae sedis	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DEZH2_k127_941597_11	1405296.Q499_0884	4.945e-06	53.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DEZH2_k127_941597_1	1304875.JAFZ01000001_gene1313	2.519e-84	294.0	COG1132@1|root,COG1132@2|Bacteria,3TAG9@508458|Synergistetes	508458|Synergistetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DEZH2_k127_9463218_1	639030.JHVA01000001_gene2886	6.191e-05	54.0	28MS6@1|root,2ZB0K@2|Bacteria,3Y38I@57723|Acidobacteria,2JHU5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_9463218_0	1485545.JQLW01000001_gene1478	7.609e-11	63.0	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DEZH2_k127_9469150_5	255470.cbdbA1572	3.469e-12	80.0	COG1361@1|root,COG1361@2|Bacteria,2G9MH@200795|Chloroflexi,34DMQ@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_9469150_6	340099.Teth39_1000	5.644e-08	66.0	COG2385@1|root,COG3409@1|root,COG2385@2|Bacteria,COG3409@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,42FS4@68295|Thermoanaerobacterales	186801|Clostridia	D	Stage II sporulation D domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
DEZH2_k127_9469150_4	262543.Exig_2661	1.026e-27	120.0	COG3764@1|root,COG3764@2|Bacteria,1V79B@1239|Firmicutes,4HJ8C@91061|Bacilli	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
DEZH2_k127_9469150_2	1384049.CD29_10315	3.124e-85	289.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3IWW9@400634|Lysinibacillus	91061|Bacilli	J	Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DEZH2_k127_9469150_3	403833.Pmob_0210	6.686e-53	212.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GC6R@200918|Thermotogae	200918|Thermotogae	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
DEZH2_k127_9469150_0	760568.Desku_0005	4.005e-208	668.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DEZH2_k127_9469150_1	485913.Krac_3454	1.278e-168	548.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
DEZH2_k127_9495397_3	944481.JAFP01000001_gene1197	1.563e-18	89.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2WPHH@28221|Deltaproteobacteria,2M74T@213113|Desulfurellales	28221|Deltaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DEZH2_k127_9495397_5	927704.SELR_00940	6.907e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,1TR6I@1239|Firmicutes,4H1YP@909932|Negativicutes	909932|Negativicutes	EGP	Drug resistance transporter Bcr CflA subfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
DEZH2_k127_9495397_2	754436.JCM19237_2430	2.634e-30	129.0	COG1072@1|root,COG1072@2|Bacteria,1RA07@1224|Proteobacteria,1S2M0@1236|Gammaproteobacteria,1XWP1@135623|Vibrionales	135623|Vibrionales	H	Phosphoribulokinase / Uridine kinase family	-	-	-	ko:K02173	-	-	-	-	ko00000	-	-	-	PRK
DEZH2_k127_9495397_0	1031288.AXAA01000007_gene913	9.737e-131	442.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,36DE5@31979|Clostridiaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
DEZH2_k127_9495397_1	926569.ANT_11300	2.394e-65	245.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DEZH2_k127_9495397_4	255470.cbdbA1641	2.722e-06	53.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,34DHN@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
DEZH2_k127_9575013_1	867845.KI911784_gene1893	1.091e-50	198.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DEZH2_k127_9575013_0	1234664.AMRO01000071_gene3085	5.153e-62	222.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,1WG55@129337|Geobacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DEZH2_k127_9575013_3	1380600.AUYN01000001_gene2880	2.919e-16	84.0	2EFIY@1|root,339BC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_9575013_2	381764.Fnod_0957	3.242e-37	149.0	COG2859@1|root,COG2859@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
DEZH2_k127_9575013_4	1185653.A1A1_00595	3.755e-06	60.0	COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4HA2V@91061|Bacilli,26CXW@186818|Planococcaceae	91061|Bacilli	M	Cell Wall Hydrolase	sleB	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,PG_binding_1
DEZH2_k127_9709711_1	1444310.JANV01000028_gene1590	3.927e-79	271.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DEZH2_k127_9709711_3	908338.HMPREF9286_1409	1.866e-38	146.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,22GBX@1570339|Peptoniphilaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DEZH2_k127_9709711_2	445961.IW15_21825	7.826e-39	152.0	29Y6H@1|root,30K00@2|Bacteria,4NNYZ@976|Bacteroidetes,1I2RD@117743|Flavobacteriia,3ZNME@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
DEZH2_k127_9709711_4	1267535.KB906767_gene3686	1.929e-27	123.0	29M6H@1|root,3083Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DEZH2_k127_9709711_0	1169144.KB910930_gene1663	6.934e-153	491.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
DEZH2_k127_9941337_3	1121381.JNIV01000129_gene553	0.0001124	46.0	COG0690@1|root,COG0690@2|Bacteria,1WKRY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
DEZH2_k127_9941337_0	1121430.JMLG01000024_gene68	6.561e-62	217.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,260QW@186807|Peptococcaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
DEZH2_k127_9941337_1	1541959.KQ51_00158	4.387e-51	184.0	COG0080@1|root,COG0080@2|Bacteria,3WTDP@544448|Tenericutes	544448|Tenericutes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DEZH2_k127_9941337_2	861299.J421_0937	1.377e-17	83.0	2E5BC@1|root,3303G@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpJ	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
## 669 queries scanned
## Total time (seconds): 1.8233132362365723
## Rate: 366.91 q/s