## Sat Dec 13 10:30:14 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/DPH1_bin.5.fa -m mmseqs --itype genome -o DPH1_bin.5 --output_dir /data/result/bins/wyx/egg/DPH1_bin.5 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DPH1_k127_10178121_1	929562.Emtol_3159	2.506e-47	187.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DPH1_k127_10178121_3	589924.Ferp_1065	3.706e-17	94.0	COG3979@1|root,arCOG02537@1|root,arCOG02537@2157|Archaea,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_10178121_2	926550.CLDAP_02020	3.724e-45	187.0	COG1520@1|root,COG1520@2|Bacteria,2G93W@200795|Chloroflexi	200795|Chloroflexi	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_10178121_0	489825.LYNGBM3L_10620	6.366e-64	229.0	COG3315@1|root,COG3315@2|Bacteria,1G5DY@1117|Cyanobacteria,1HFS2@1150|Oscillatoriales	1117|Cyanobacteria	H	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
DPH1_k127_10178121_4	742727.HMPREF9447_05068	0.0001788	53.0	COG3591@1|root,COG4886@1|root,COG3591@2|Bacteria,COG4886@2|Bacteria,4PN4C@976|Bacteroidetes,2FVP7@200643|Bacteroidia,4ASX5@815|Bacteroidaceae	976|Bacteroidetes	E	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10182557_12	1094980.Mpsy_1117	2.254e-48	198.0	arCOG02488@1|root,arCOG02488@2157|Archaea	2157|Archaea	E	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CHB_HEX_C_1,PKD
DPH1_k127_10182557_10	593750.Metfor_0576	2.074e-51	192.0	arCOG08211@1|root,arCOG08211@2157|Archaea,2XW85@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10182557_8	645991.Sgly_0225	2.198e-58	215.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,26001@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
DPH1_k127_10182557_13	635013.TherJR_2632	1.156e-47	187.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_10182557_6	387631.Asulf_00373	1.988e-73	256.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,2460M@183980|Archaeoglobi	183980|Archaeoglobi	E	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_10182557_15	521011.Mpal_0271	8.112e-30	134.0	COG1361@1|root,arCOG04400@2157|Archaea,2XZN3@28890|Euryarchaeota,2N9X5@224756|Methanomicrobia	224756|Methanomicrobia	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10182557_17	456442.Mboo_1018	2.749e-21	99.0	COG1695@1|root,arCOG00002@2157|Archaea,2Y1PS@28890|Euryarchaeota,2NBA8@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DPH1_k127_10182557_5	1220534.B655_1140	8.218e-82	286.0	COG0842@1|root,arCOG01463@2157|Archaea,2XWB7@28890|Euryarchaeota	28890|Euryarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DPH1_k127_10182557_4	877455.Metbo_2056	2.357e-82	282.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWVA@28890|Euryarchaeota	28890|Euryarchaeota	E	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_10182557_18	237368.SCABRO_00207	2.886e-21	108.0	COG1572@1|root,COG2931@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG5276@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,COG5276@2|Bacteria,2J3BU@203682|Planctomycetes	203682|Planctomycetes	Q	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10182557_19	1968.JOEV01000002_gene7129	1.484e-07	63.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
DPH1_k127_10182557_16	877455.Metbo_2019	1.446e-26	111.0	COG0640@1|root,arCOG00731@2157|Archaea,2XYSK@28890|Euryarchaeota	28890|Euryarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
DPH1_k127_10182557_3	945713.IALB_2614	8.923e-106	353.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DPH1_k127_10182557_9	410358.Mlab_0997	1.952e-52	192.0	COG1392@1|root,arCOG02640@2157|Archaea	2157|Archaea	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DPH1_k127_10182557_11	1343739.PAP_03580	4.746e-49	186.0	COG1409@1|root,arCOG01153@2157|Archaea,2XWZF@28890|Euryarchaeota,242KP@183968|Thermococci	183968|Thermococci	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DPH1_k127_10182557_1	456442.Mboo_2400	1.737e-111	370.0	COG0704@1|root,arCOG00318@2157|Archaea,2XUA4@28890|Euryarchaeota,2NADX@224756|Methanomicrobia	224756|Methanomicrobia	K	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
DPH1_k127_10182557_14	1031288.AXAA01000018_gene34	7.221e-38	155.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,36F61@31979|Clostridiaceae	186801|Clostridia	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
DPH1_k127_10182557_0	410358.Mlab_1117	5.08e-112	384.0	COG0581@1|root,arCOG00168@2157|Archaea,2Y8DS@28890|Euryarchaeota,2N9FR@224756|Methanomicrobia	224756|Methanomicrobia	P	phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DPH1_k127_10182557_2	323259.Mhun_2983	3.409e-111	365.0	COG1117@1|root,arCOG00231@2157|Archaea,2XTJK@28890|Euryarchaeota,2N93D@224756|Methanomicrobia	224756|Methanomicrobia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
DPH1_k127_10182557_7	368407.Memar_2279	7.5e-73	252.0	COG0704@1|root,arCOG00232@2157|Archaea,2XUZ9@28890|Euryarchaeota,2N9W2@224756|Methanomicrobia	224756|Methanomicrobia	P	Plays a role in the regulation of phosphate uptake	phoU-2	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
DPH1_k127_10588848_42	549.BW31_02345	0.0006407	49.0	COG1522@1|root,COG1522@2|Bacteria,1RIEU@1224|Proteobacteria,1S28Y@1236|Gammaproteobacteria,3W04G@53335|Pantoea	1236|Gammaproteobacteria	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_10588848_4	1236689.MMALV_15100	2.719e-116	387.0	COG0126@1|root,arCOG00496@2157|Archaea,2XSXX@28890|Euryarchaeota,3F2JM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DPH1_k127_10588848_3	1304880.JAGB01000002_gene2026	3.225e-132	430.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DPH1_k127_10588848_6	565033.GACE_0567	1.725e-102	347.0	COG0621@1|root,arCOG01358@2157|Archaea,2XSVB@28890|Euryarchaeota,2460N@183980|Archaeoglobi	183980|Archaeoglobi	J	MiaB-like tRNA modifying enzyme	-	-	2.8.4.5	ko:K15865	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DPH1_k127_10588848_2	309799.DICTH_0773	1.35e-152	499.0	COG1384@1|root,COG1384@2|Bacteria	2|Bacteria	J	tRNA binding	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
DPH1_k127_10588848_11	439481.Aboo_1417	6.545e-58	207.0	COG0856@1|root,arCOG00028@2157|Archaea,2XU2R@28890|Euryarchaeota,3F30G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	pyrE1	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
DPH1_k127_10588848_39	273116.14324537	4.884e-06	52.0	COG4023@1|root,arCOG02957@2157|Archaea,2Y1AH@28890|Euryarchaeota,242FI@183967|Thermoplasmata	183967|Thermoplasmata	U	but it may be involved in stabilization of the trimeric complex	secG	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
DPH1_k127_10588848_0	192952.MM_1486	1.353e-211	689.0	COG0013@1|root,arCOG01255@2157|Archaea,2XSXB@28890|Euryarchaeota,2N92P@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DPH1_k127_10588848_41	997884.HMPREF1068_00362	3.723e-05	56.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
DPH1_k127_10588848_9	273116.14324729	5.475e-68	238.0	COG1709@1|root,arCOG04060@2157|Archaea,2XT58@28890|Euryarchaeota,241N9@183967|Thermoplasmata	183967|Thermoplasmata	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07731	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
DPH1_k127_10588848_37	519442.Huta_0925	6.677e-07	52.0	arCOG06415@1|root,arCOG06415@2157|Archaea	2157|Archaea	L	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	zf-HIT
DPH1_k127_10588848_36	123214.PERMA_0937	2.256e-09	71.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_10588848_22	1121448.DGI_1843	8.094e-26	125.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1QU1I@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Peptidase_S8
DPH1_k127_10588848_29	1150474.JQJI01000027_gene967	6.967e-21	107.0	COG1404@1|root,COG1404@2|Bacteria,2GCI9@200918|Thermotogae	200918|Thermotogae	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DPH1_k127_10588848_40	877455.Metbo_1862	6.704e-06	49.0	COG0798@1|root,arCOG02190@2157|Archaea,2XTQC@28890|Euryarchaeota,23P72@183925|Methanobacteria	183925|Methanobacteria	P	Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
DPH1_k127_10588848_35	1047013.AQSP01000122_gene2224	4.537e-11	77.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
DPH1_k127_10588848_23	351160.RCIX1696	2.736e-22	115.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10588848_33	945713.IALB_1715	5.564e-13	84.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,F5_F8_type_C
DPH1_k127_10588848_38	945713.IALB_0843	4.62e-06	61.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
DPH1_k127_10588848_19	459349.CLOAM0442	3.041e-31	145.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
DPH1_k127_10588848_32	351160.RCIX1696	4.169e-15	90.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10588848_25	1464048.JNZS01000027_gene1888	4.577e-22	113.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2HU5X@201174|Actinobacteria,4DBT0@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cleaved_Adhesin,Kelch_1,Peptidase_S8
DPH1_k127_10588848_18	459349.CLOAM0442	1.096e-31	145.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
DPH1_k127_10588848_10	459349.CLOAM0984	1.034e-60	236.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DPH1_k127_10588848_12	459349.CLOAM1811	3.237e-57	225.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K06987,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,DUF4859,FlgD_ig,Peptidase_M14
DPH1_k127_10588848_28	1041930.Mtc_0021	1.266e-21	98.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,2NAXV@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DPH1_k127_10588848_13	647113.Metok_1036	4.488e-57	217.0	COG0642@1|root,arCOG02322@1|root,arCOG02322@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,23RVT@183939|Methanococci	183939|Methanococci	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
DPH1_k127_10588848_34	1173029.JH980292_gene816	9.151e-13	80.0	COG0642@1|root,COG3707@1|root,COG3920@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3707@2|Bacteria,COG3920@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1HI0U@1150|Oscillatoriales	1117|Cyanobacteria	T	HWE histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_10588848_1	272844.PAB1810	1.478e-153	496.0	COG0436@1|root,arCOG01131@2157|Archaea,2XVXM@28890|Euryarchaeota,243JD@183968|Thermococci	183968|Thermococci	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DPH1_k127_10588848_30	673860.AciM339_1416	1.298e-15	80.0	COG0011@1|root,arCOG04373@2157|Archaea,2Y6H3@28890|Euryarchaeota,3F3EY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
DPH1_k127_10588848_15	246969.TAM4_1107	1.31e-43	167.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,243DZ@183968|Thermococci	183968|Thermococci	C	pyruvate synthase activity	porG	-	1.2.7.1,1.2.7.7	ko:K00172,ko:K00189	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
DPH1_k127_10588848_21	444158.MmarC6_1168	8.336e-27	111.0	COG1144@1|root,arCOG01605@2157|Archaea,2Y02N@28890|Euryarchaeota,23R52@183939|Methanococci	183939|Methanococci	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
DPH1_k127_10588848_5	1343739.PAP_04310	2.227e-110	369.0	COG0674@1|root,arCOG01608@2157|Archaea,2XTB0@28890|Euryarchaeota,242N1@183968|Thermococci	183968|Thermococci	C	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	vorA	-	1.2.7.7	ko:K00186	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	PFOR_II,POR_N
DPH1_k127_10588848_8	387631.Asulf_00879	6.171e-92	311.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,246RX@183980|Archaeoglobi	183980|Archaeoglobi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DPH1_k127_10588848_16	1220534.B655_2366	4.578e-35	145.0	COG1829@1|root,arCOG04263@2157|Archaea,2XST6@28890|Euryarchaeota,23P1W@183925|Methanobacteria	183925|Methanobacteria	S	GHMP kinases N terminal domain	coaA	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
DPH1_k127_10588848_7	1236689.MMALV_01380	9.044e-96	327.0	COG0452@1|root,arCOG01704@2157|Archaea,2XTZK@28890|Euryarchaeota,3F2J3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DPH1_k127_10588848_31	656519.Halsa_0185	1.783e-15	81.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DPH1_k127_10588848_14	1236689.MMALV_09970	3.944e-48	178.0	COG1591@1|root,arCOG00919@2157|Archaea,2XY2Q@28890|Euryarchaeota,3F2NJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Archaeal holliday junction resolvase (hjc)	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
DPH1_k127_10588848_17	573063.Metin_0860	1.866e-34	139.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,23QUR@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_10588848_20	339860.Msp_1428	1.229e-28	125.0	COG0517@1|root,arCOG00600@2157|Archaea,2Y88W@28890|Euryarchaeota,23NZQ@183925|Methanobacteria	183925|Methanobacteria	S	SMART Cystathionine beta-synthase, core	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_10588848_27	673860.AciM339_0276	1.134e-21	99.0	arCOG13537@1|root,arCOG13537@2157|Archaea,2Y1U2@28890|Euryarchaeota,3F2T4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10588848_26	644281.MFS40622_1254	6.735e-22	99.0	COG3373@1|root,arCOG03422@2157|Archaea,2XZ1J@28890|Euryarchaeota,23RV0@183939|Methanococci	183939|Methanococci	K	Winged helix DNA-binding domain (DUF1495)	-	-	-	ko:K09745	-	-	-	-	ko00000	-	-	-	DUF1495
DPH1_k127_10588848_24	247490.KSU1_C0730	2.749e-22	112.0	COG2234@1|root,COG3291@1|root,COG3420@1|root,COG4409@1|root,COG5184@1|root,COG5276@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4409@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	iap	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6	ko:K01179,ko:K03929,ko:K09612,ko:K12287,ko:K19701,ko:K19702	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02044	-	CE10,GH5,GH9	-	Beta_helix,Peptidase_M28
DPH1_k127_10779693_4	224325.AF_1181	2.537e-88	297.0	COG1100@1|root,arCOG00354@2157|Archaea,2XT36@28890|Euryarchaeota,246VT@183980|Archaeoglobi	183980|Archaeoglobi	S	GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	MMR_HSR1
DPH1_k127_10779693_10	387631.Asulf_00992	4.576e-28	117.0	COG3365@1|root,arCOG04416@2157|Archaea,2XX2F@28890|Euryarchaeota,246AQ@183980|Archaeoglobi	183980|Archaeoglobi	S	Uncharacterized protein conserved in archaea (DUF2073)	-	-	-	ko:K09743	-	-	-	-	ko00000	-	-	-	DUF2073
DPH1_k127_10779693_15	269797.Mbar_A0911	2.105e-17	89.0	COG3364@1|root,arCOG04417@2157|Archaea,2Y0WK@28890|Euryarchaeota,2N9ZI@224756|Methanomicrobia	224756|Methanomicrobia	S	Zn-ribbon containing protein	-	-	-	ko:K07163	-	-	-	-	ko00000	-	-	-	DUF2072
DPH1_k127_10779693_1	673860.AciM339_0989	7.711e-143	466.0	COG0112@1|root,arCOG00070@2157|Archaea,2XU0H@28890|Euryarchaeota,3F2G1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DPH1_k127_10779693_9	572546.Arcpr_0279	8.711e-34	136.0	COG1936@1|root,arCOG01038@2157|Archaea,2XX2A@28890|Euryarchaeota,246B1@183980|Archaeoglobi	183980|Archaeoglobi	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
DPH1_k127_10779693_6	1236689.MMALV_00620	2.749e-58	212.0	COG0558@1|root,arCOG00670@2157|Archaea,2XWJ0@28890|Euryarchaeota,3F2ME@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.39,2.7.8.5	ko:K00995,ko:K17884	ko00564,ko01100,map00564,map01100	-	R01801,R10464	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A1250	CDP-OH_P_transf
DPH1_k127_10779693_17	192952.MM_3318	3.275e-13	80.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_10779693_5	272844.PAB0722	1.724e-69	252.0	COG2262@1|root,arCOG00353@2157|Archaea,2XT2W@28890|Euryarchaeota,2431W@183968|Thermococci	183968|Thermococci	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DPH1_k127_10779693_23	1280682.AUKA01000003_gene1172	5.491e-05	55.0	2E8MK@1|root,332Z1@2|Bacteria,1VEEU@1239|Firmicutes,24R8Y@186801|Clostridia,4BZH0@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
DPH1_k127_10779693_14	266117.Rxyl_1254	4.398e-18	93.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4CU00@84995|Rubrobacteria	84995|Rubrobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DPH1_k127_10779693_20	123214.PERMA_0937	1.084e-08	67.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_10779693_0	673860.AciM339_0648	2.28e-225	714.0	COG1245@1|root,arCOG00187@2157|Archaea,2XSZE@28890|Euryarchaeota,3F2G2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	metal-binding domain in RNase L inhibitor, RLI	rli	GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
DPH1_k127_10779693_3	693661.Arcve_1018	1.098e-110	370.0	COG0513@1|root,arCOG00558@2157|Archaea,2XUS4@28890|Euryarchaeota	28890|Euryarchaeota	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
DPH1_k127_10779693_13	1423816.BACQ01000075_gene2599	1.491e-18	86.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae	91061|Bacilli	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DPH1_k127_10779693_19	1336803.PHEL49_1355	1.378e-10	75.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Pur_ac_phosph_N
DPH1_k127_10779693_7	760192.Halhy_5115	1.944e-50	186.0	2DBX9@1|root,2ZBN9@2|Bacteria,4NVAY@976|Bacteroidetes,1IZRN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10779693_21	269797.Mbar_A1020	1.183e-06	53.0	arCOG03966@1|root,arCOG03966@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10779693_16	269797.Mbar_A1021	4.671e-16	80.0	COG2026@1|root,arCOG01663@2157|Archaea	2157|Archaea	DJ	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
DPH1_k127_10779693_8	573064.Mefer_1243	2.899e-38	162.0	arCOG03450@1|root,arCOG03450@2157|Archaea,2XV0N@28890|Euryarchaeota,23QR5@183939|Methanococci	183939|Methanococci	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF553
DPH1_k127_10779693_2	593117.TGAM_1056	6.325e-127	417.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,243KU@183968|Thermococci	183968|Thermococci	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
DPH1_k127_10779693_22	1047013.AQSP01000066_gene724	3.529e-06	51.0	2E5PY@1|root,330EK@2|Bacteria,2NS29@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10779693_18	263820.PTO0362	4.359e-11	70.0	COG0582@1|root,arCOG01242@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
DPH1_k127_10779693_11	192952.MM_0787	1.992e-24	109.0	COG1943@1|root,arCOG02759@2157|Archaea,2XZF1@28890|Euryarchaeota	28890|Euryarchaeota	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DPH1_k127_10779693_12	1304865.JAGF01000001_gene344	7.484e-19	100.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_11046626_43	351160.RCIX2153	0.0002535	46.0	COG2104@1|root,arCOG00535@2157|Archaea,2Y205@28890|Euryarchaeota,2NBCK@224756|Methanomicrobia	224756|Methanomicrobia	H	Sulfur transfer protein involved in thiamine biosynthesis	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DPH1_k127_11046626_45	909943.HIMB100_00019360	0.0008845	52.0	COG1261@1|root,COG4249@1|root,COG1261@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,2VFPC@28211|Alphaproteobacteria	1224|Proteobacteria	N	PFAM Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Peptidase_C14,Polysacc_deac_1,Sel1,TPR_11,TPR_16,TPR_2,TPR_8
DPH1_k127_11046626_18	525373.HMPREF0766_13313	2.467e-35	149.0	COG0457@1|root,COG3049@1|root,COG0457@2|Bacteria,COG3049@2|Bacteria,4NIRM@976|Bacteroidetes,1J18T@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycogen recognition site of AMP-activated protein kinase	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,AMPK1_CBM,CBAH
DPH1_k127_11046626_42	1094980.Mpsy_0715	3.726e-05	47.0	arCOG07235@1|root,arCOG07235@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_28	1094980.Mpsy_0716	1.348e-14	77.0	arCOG07235@1|root,arCOG07235@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_29	243232.MJ_1173	9.891e-13	71.0	COG2026@1|root,arCOG02414@2157|Archaea,2Y07R@28890|Euryarchaeota,23R7I@183939|Methanococci	183939|Methanococci	K	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
DPH1_k127_11046626_6	374847.Kcr_0638	1.074e-70	259.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DPH1_k127_11046626_2	391598.FBBAL38_09852	2.445e-89	316.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_11046626_1	391598.FBBAL38_09852	1.37e-97	340.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_11046626_12	596152.DesU5LDRAFT_2278	2.487e-56	214.0	COG1541@1|root,COG1541@2|Bacteria,1N0HG@1224|Proteobacteria,42PT8@68525|delta/epsilon subdivisions,2WIY1@28221|Deltaproteobacteria,2M7S4@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DPH1_k127_11046626_10	589924.Ferp_0042	9.172e-62	230.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,245XG@183980|Archaeoglobi	183980|Archaeoglobi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DPH1_k127_11046626_13	1220534.B655_1327	6.677e-56	199.0	COG0716@1|root,arCOG00519@2157|Archaea,2XXTN@28890|Euryarchaeota	28890|Euryarchaeota	C	Flavodoxin	-	GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3,Flavodoxin_5
DPH1_k127_11046626_23	338969.Rfer_1205	5.935e-22	98.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,4AEEU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_36	1140002.I570_01595	1.179e-07	61.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_7,Flavodoxin_5
DPH1_k127_11046626_19	304371.MCP_2194	2.653e-28	118.0	arCOG03769@1|root,arCOG03769@2157|Archaea	2157|Archaea	M	glucosylceramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_34	1324957.K933_11121	2.944e-10	65.0	2C3UT@1|root,2N61V@2157|Archaea,2Y5Q6@28890|Euryarchaeota,240A9@183963|Halobacteria	183963|Halobacteria	S	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_5	1121335.Clst_1990	4.168e-73	261.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1VRTV@1239|Firmicutes,24H21@186801|Clostridia	186801|Clostridia	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DPH1_k127_11046626_9	192952.MM_0946	2.598e-62	220.0	COG1853@1|root,arCOG02016@2157|Archaea,2XYAJ@28890|Euryarchaeota,2N9RF@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DPH1_k127_11046626_7	234267.Acid_4390	6.189e-65	235.0	COG2355@1|root,COG2355@2|Bacteria,3Y39A@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
DPH1_k127_11046626_25	1280671.AUJH01000016_gene1019	1.912e-16	92.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia,4BWHD@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,Glyco_hydro_53
DPH1_k127_11046626_17	368407.Memar_0458	6.217e-37	148.0	COG3413@1|root,arCOG02272@2157|Archaea	2157|Archaea	S	Bacterio-opsin activator HTH	-	-	1.5.1.40	ko:K06930,ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	BAT,HTH_10
DPH1_k127_11046626_0	351160.RCIX1069	5.509e-107	357.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUAX@28890|Euryarchaeota	28890|Euryarchaeota	E	COG1131 ABC-type multidrug transport system ATPase component	-	-	-	ko:K16907	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_11046626_20	1408433.JHXV01000048_gene3354	3.405e-28	123.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DPH1_k127_11046626_21	304371.MCP_1635	5.509e-28	123.0	arCOG05876@1|root,arCOG05876@2157|Archaea	2157|Archaea	-	-	-	-	-	ko:K16905,ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DPH1_k127_11046626_30	204669.Acid345_1037	6.424e-12	75.0	COG3595@1|root,COG3595@2|Bacteria,3Y97I@57723|Acidobacteria,2JNRB@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_39	326442.PSHAb0429	1.558e-06	55.0	COG1522@1|root,COG1522@2|Bacteria,1RH53@1224|Proteobacteria,1S493@1236|Gammaproteobacteria,2Q29D@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_11046626_8	234267.Acid_6745	1.775e-64	226.0	COG0252@1|root,COG0252@2|Bacteria,3Y8TG@57723|Acidobacteria	57723|Acidobacteria	EJ	Asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DPH1_k127_11046626_44	1198449.ACAM_0349	0.0005064	46.0	COG0517@1|root,COG1522@1|root,arCOG00606@2157|Archaea,arCOG01117@2157|Archaea,2XRRU@28889|Crenarchaeota	28889|Crenarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,CBS
DPH1_k127_11046626_31	688246.Premu_2381	2.404e-11	70.0	COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,2FPN5@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator, AsnC family	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_11046626_32	195522.BD01_1564	6.132e-11	72.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX3W@28890|Euryarchaeota,2442A@183968|Thermococci	183968|Thermococci	K	Transcriptional regulator	lrpA	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_11046626_22	521011.Mpal_2431	5.58e-27	112.0	COG3432@1|root,arCOG01055@2157|Archaea,2Y1SU@28890|Euryarchaeota	28890|Euryarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
DPH1_k127_11046626_33	521011.Mpal_2432	9.055e-11	70.0	arCOG09490@1|root,arCOG09490@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_24	186497.PF0663	4.259e-18	96.0	arCOG04380@1|root,arCOG04380@2157|Archaea,2Y4IJ@28890|Euryarchaeota,243B7@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_37	471854.Dfer_4831	2.74e-07	56.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes,47SBV@768503|Cytophagia	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
DPH1_k127_11046626_14	269797.Mbar_A1048	2.061e-54	198.0	COG1985@1|root,arCOG01489@2157|Archaea,2Y3RM@28890|Euryarchaeota,2NAWI@224756|Methanomicrobia	224756|Methanomicrobia	C	RibD C-terminal domain	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
DPH1_k127_11046626_4	269797.Mbar_A1359	3.33e-73	249.0	arCOG05193@1|root,arCOG05193@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11046626_11	357808.RoseRS_3668	1.853e-61	216.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DPH1_k127_11046626_26	926561.KB900622_gene463	2.187e-15	81.0	29X3G@1|root,30IS5@2|Bacteria,1W5BE@1239|Firmicutes,24MZE@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
DPH1_k127_11046626_15	660470.Theba_2261	1.078e-49	181.0	2DH26@1|root,2ZY4Z@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
DPH1_k127_11046626_16	395961.Cyan7425_3686	9.282e-44	167.0	COG4430@1|root,COG4430@2|Bacteria,1G2ES@1117|Cyanobacteria,3KK2F@43988|Cyanothece	1117|Cyanobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
DPH1_k127_11046626_38	13035.Dacsa_2281	4.662e-07	64.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PPC,Peptidase_S8
DPH1_k127_11046626_35	649349.Lbys_0679	1.942e-08	66.0	COG3656@1|root,COG3656@2|Bacteria,4NHDQ@976|Bacteroidetes,47PJR@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III domain protein	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	-
DPH1_k127_11046626_3	269797.Mbar_A3576	2.404e-76	263.0	COG3369@1|root,arCOG03174@2157|Archaea,2XX0Q@28890|Euryarchaeota,2NAIG@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART zinc finger, CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
DPH1_k127_11046626_40	7668.SPU_018702-tr	2.183e-06	55.0	COG0526@1|root,KOG0912@2759|Eukaryota,38C3I@33154|Opisthokonta,3BFES@33208|Metazoa,3CU7X@33213|Bilateria	33208|Metazoa	CO	cell redox homeostasis	ERP44	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0005793,GO:0006457,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006986,GO:0008150,GO:0008152,GO:0009100,GO:0009986,GO:0009987,GO:0010033,GO:0012505,GO:0015036,GO:0015037,GO:0016020,GO:0016192,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0019725,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0031984,GO:0032940,GO:0033554,GO:0034774,GO:0034976,GO:0035580,GO:0035966,GO:0036230,GO:0042119,GO:0042175,GO:0042221,GO:0042581,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045454,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055114,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0097708,GO:0098827,GO:0099503,GO:0140096,GO:1901135,GO:1901564	-	ko:K17264	-	-	-	-	ko00000,ko04131,ko04147	-	-	-	Thioredoxin,Thioredoxin_6
DPH1_k127_11046626_41	459349.CLOAM0164	3.023e-05	57.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DPH1_k127_11046626_27	387631.Asulf_00521	3.055e-15	90.0	COG3979@1|root,COG5306@1|root,arCOG02420@1|root,arCOG03511@1|root,arCOG03553@1|root,arCOG09173@1|root,arCOG02420@2157|Archaea,arCOG03508@2157|Archaea,arCOG03511@2157|Archaea,arCOG03553@2157|Archaea,arCOG07581@2157|Archaea,arCOG09173@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF2341,PKD,Pilin_N,S_layer_C
DPH1_k127_11346457_0	645991.Sgly_0152	9.058e-165	532.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia,2633J@186807|Peptococcaceae	186801|Clostridia	Q	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DPH1_k127_11346457_1	755732.Fluta_0010	2.444e-06	59.0	COG0296@1|root,COG2957@1|root,COG0296@2|Bacteria,COG2957@2|Bacteria,4NJ5R@976|Bacteroidetes,1I7K9@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family C25, C terminal ig-like domain	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37	ko:K08589	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DPH1_k127_11566256_2	768706.Desor_3179	1.587e-12	71.0	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,262NZ@186807|Peptococcaceae	186801|Clostridia	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,LRR_5
DPH1_k127_11566256_0	1192034.CAP_8277	2.416e-76	279.0	COG3266@1|root,COG3266@2|Bacteria,1QZBM@1224|Proteobacteria,42TG7@68525|delta/epsilon subdivisions,2WQPM@28221|Deltaproteobacteria,2Z3I2@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
DPH1_k127_11566256_3	192952.MM_3318	1.878e-06	59.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_11566256_1	592029.DDD_0451	1.035e-72	257.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
DPH1_k127_11633202_7	323259.Mhun_0644	5.15e-07	61.0	COG3291@1|root,COG4870@1|root,arCOG02501@1|root,arCOG06738@1|root,arCOG02501@2157|Archaea,arCOG02510@2157|Archaea,arCOG03607@2157|Archaea,arCOG06738@2157|Archaea,2XWQ1@28890|Euryarchaeota,2NAG9@224756|Methanomicrobia	224756|Methanomicrobia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	NosD,PKD,Peptidase_C1
DPH1_k127_11633202_5	468059.AUHA01000007_gene2697	4.301e-29	126.0	2CYFR@1|root,32T44@2|Bacteria,4P6IN@976|Bacteroidetes,1IZDY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
DPH1_k127_11633202_8	1121472.AQWN01000002_gene2079	0.0005076	46.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,264CJ@186807|Peptococcaceae	186801|Clostridia	T	PFAM histidine kinase, HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
DPH1_k127_11633202_0	909663.KI867150_gene2678	6.496e-266	848.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MR1B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	acs	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
DPH1_k127_11633202_2	660470.Theba_2008	1.823e-48	187.0	COG1409@1|root,COG1409@2|Bacteria,2GDAI@200918|Thermotogae	200918|Thermotogae	P	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DPH1_k127_11633202_1	572546.Arcpr_1838	2.043e-53	199.0	COG0697@1|root,arCOG00271@2157|Archaea,2XXKE@28890|Euryarchaeota,2466R@183980|Archaeoglobi	183980|Archaeoglobi	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_11633202_4	1041930.Mtc_2505	2.409e-44	175.0	COG1499@1|root,arCOG04149@2157|Archaea,2XUAI@28890|Euryarchaeota,2N9GP@224756|Methanomicrobia	224756|Methanomicrobia	J	pfam nmd3	-	-	-	ko:K07562	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko03009	-	-	-	NMD3
DPH1_k127_11633202_6	999630.TUZN_1110	2.539e-09	65.0	COG1247@1|root,arCOG00830@2157|Archaea	2157|Archaea	M	COG1247 Sortase and related acyltransferases	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
DPH1_k127_11633202_3	1343739.PAP_07180	2.419e-46	181.0	COG0101@1|root,arCOG04449@2157|Archaea,2XTH5@28890|Euryarchaeota,242SP@183968|Thermococci	183968|Thermococci	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
DPH1_k127_11711707_3	589924.Ferp_0541	3.631e-32	131.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_11711707_1	579137.Metvu_0743	4.323e-50	192.0	COG3276@1|root,arCOG01564@2157|Archaea,2XWBV@28890|Euryarchaeota,23QFU@183939|Methanococci	183939|Methanococci	J	PFAM elongation factor Tu, domain 2 protein	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
DPH1_k127_11711707_2	1499967.BAYZ01000090_gene4984	1.318e-42	161.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4,Flavodoxin_5
DPH1_k127_11711707_0	70601.3256752	4.679e-127	430.0	COG1297@1|root,arCOG04807@2157|Archaea,2XVCD@28890|Euryarchaeota,243GY@183968|Thermococci	183968|Thermococci	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DPH1_k127_12030627_19	1304880.JAGB01000002_gene1841	5.692e-31	123.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
DPH1_k127_12030627_13	1443665.JACA01000012_gene1291	4.316e-60	231.0	COG1404@1|root,COG4249@1|root,COG1404@2|Bacteria,COG4249@2|Bacteria,4PHQW@976|Bacteroidetes,1I5CW@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_12030627_35	1320556.AVBP01000007_gene617	0.0008329	48.0	COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,2U74K@28211|Alphaproteobacteria,43KAK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_12030627_33	868131.MSWAN_0268	2.308e-05	57.0	arCOG02552@1|root,arCOG02552@2157|Archaea	2157|Archaea	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
DPH1_k127_12030627_24	374847.Kcr_0417	3.071e-16	92.0	arCOG02499@1|root,arCOG02499@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
DPH1_k127_12030627_27	1121272.KB903249_gene1743	5.035e-09	69.0	COG0823@1|root,COG0823@2|Bacteria,2IC0F@201174|Actinobacteria,4DGB3@85008|Micromonosporales	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SLH
DPH1_k127_12030627_5	1134413.ANNK01000103_gene885	9.429e-87	291.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,1ZDT7@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
DPH1_k127_12030627_11	459349.CLOAM0030	2.129e-60	235.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.17.22	ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Cellulase,DUF4859,F5_F8_type_C,FlgD_ig
DPH1_k127_12030627_22	485914.Hmuk_2921	8.612e-18	98.0	COG3979@1|root,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PKD
DPH1_k127_12030627_17	573061.Clocel_3128	9.544e-46	181.0	COG0621@1|root,COG0621@2|Bacteria,1UY0Y@1239|Firmicutes,24EH9@186801|Clostridia,36SBG@31979|Clostridiaceae	186801|Clostridia	J	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
DPH1_k127_12030627_26	944479.JQLX01000014_gene1522	2.269e-11	66.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2M70X@213113|Desulfurellales	28221|Deltaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
DPH1_k127_12030627_34	489825.LYNGBM3L_03900	0.0007651	51.0	COG4385@1|root,COG5295@1|root,COG4385@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K09942,ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Peptidase_S74,YadA_head,YadA_stalk
DPH1_k127_12030627_25	448385.sce2398	1.302e-15	89.0	COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
DPH1_k127_12030627_31	192952.MM_2587	9.26e-07	60.0	COG3291@1|root,arCOG02496@1|root,arCOG02496@2157|Archaea,arCOG02507@2157|Archaea,2Y7MW@28890|Euryarchaeota	2157|Archaea	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,HYR,NosD,PKD
DPH1_k127_12030627_30	1392490.JHZX01000001_gene3072	7.227e-07	62.0	COG3055@1|root,COG3055@2|Bacteria,4NMHY@976|Bacteroidetes,1I1DN@117743|Flavobacteriia	976|Bacteroidetes	Q	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
DPH1_k127_12030627_6	374847.Kcr_0638	2.978e-86	308.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DPH1_k127_12030627_32	368408.Tpen_0381	1.579e-06	59.0	COG3863@1|root,arCOG04437@2157|Archaea,2XS05@28889|Crenarchaeota	28889|Crenarchaeota	S	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
DPH1_k127_12030627_21	2002.JOEQ01000036_gene647	1.885e-21	104.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4EH9T@85012|Streptosporangiales	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
DPH1_k127_12030627_7	269797.Mbar_A2315	5.193e-85	290.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,2N9EP@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DPH1_k127_12030627_10	368407.Memar_0327	4.151e-64	228.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota,2N9R3@224756|Methanomicrobia	224756|Methanomicrobia	V	TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DPH1_k127_12030627_3	192952.MM_2455	3.136e-108	359.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DPH1_k127_12030627_20	1333523.L593_07745	4.588e-26	117.0	COG0500@1|root,arCOG04583@2157|Archaea,2XTVC@28890|Euryarchaeota,23ST5@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DPH1_k127_12030627_1	868131.MSWAN_1300	9.807e-141	466.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,23NX2@183925|Methanobacteria	183925|Methanobacteria	J	Phenylalanyl-tRNA synthetase beta	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,tRNA-synt_2d
DPH1_k127_12030627_8	693661.Arcve_1306	2.748e-66	240.0	COG2237@1|root,arCOG04151@2157|Archaea,2XTV5@28890|Euryarchaeota,2463A@183980|Archaeoglobi	183980|Archaeoglobi	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
DPH1_k127_12030627_12	673860.AciM339_0749	3.78e-60	226.0	COG0517@1|root,COG0750@1|root,arCOG00607@2157|Archaea,arCOG04064@2157|Archaea,2XSZP@28890|Euryarchaeota,3F2KK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
DPH1_k127_12030627_15	1041930.Mtc_0068	1.311e-55	199.0	COG0197@1|root,arCOG04113@2157|Archaea,2XTHT@28890|Euryarchaeota,2N9MZ@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the universal ribosomal protein uL16 family	rpl10e	-	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DPH1_k127_12030627_18	272844.PAB2314	4.01e-38	149.0	COG1096@1|root,arCOG00676@2157|Archaea,2XYYA@28890|Euryarchaeota,243T0@183968|Thermococci	183968|Thermococci	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,EXOSC1
DPH1_k127_12030627_29	1041930.Mtc_1740	5.665e-07	55.0	COG1761@1|root,arCOG04111@2157|Archaea,2XYYQ@28890|Euryarchaeota,2NA0Z@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoL	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
DPH1_k127_12030627_4	1236689.MMALV_11840	1.097e-94	326.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,3F2I5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
DPH1_k127_12030627_0	1304880.JAGB01000002_gene2135	0.0	1104.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DPH1_k127_12030627_28	1047013.AQSP01000122_gene2224	1.024e-07	64.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
DPH1_k127_12030627_2	1054217.TALC_01456	2.163e-136	441.0	COG0533@1|root,arCOG01183@2157|Archaea,2Y86G@28890|Euryarchaeota	28890|Euryarchaeota	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity	kae1	GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DPH1_k127_12030627_16	272844.PAB1047	1.536e-47	178.0	COG0533@1|root,arCOG01185@2157|Archaea,2XX5D@28890|Euryarchaeota,2436E@183968|Thermococci	183968|Thermococci	T	serine threonine protein kinase	-	GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	RIO1
DPH1_k127_12030627_14	186497.PF0249	6.833e-58	207.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,243RS@183968|Thermococci	183968|Thermococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DPH1_k127_12030627_9	394503.Ccel_1045	6.451e-66	241.0	COG0621@1|root,COG0621@2|Bacteria,1UY0Y@1239|Firmicutes,24EH9@186801|Clostridia,36SBG@31979|Clostridiaceae	186801|Clostridia	J	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
DPH1_k127_12030627_23	1463887.KL590011_gene4056	2.973e-16	90.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DPH1_k127_12036238_31	673860.AciM339_0115	1.319e-07	53.0	COG2888@1|root,arCOG01989@2157|Archaea,2Y6XW@28890|Euryarchaeota,3F2UA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Domain of unknown function (DUF1610)	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	DUF1610
DPH1_k127_12036238_23	192952.MM_0377	7.518e-52	197.0	COG0392@1|root,arCOG00899@2157|Archaea,2XY3K@28890|Euryarchaeota,2NAER@224756|Methanomicrobia	224756|Methanomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DPH1_k127_12036238_13	439481.Aboo_0737	5.417e-78	271.0	COG0535@1|root,arCOG00938@2157|Archaea,2XZ9M@28890|Euryarchaeota,3F34T@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Radical_SAM,SPASM
DPH1_k127_12036238_6	631362.Thi970DRAFT_03635	1.16e-99	338.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,1WX72@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
DPH1_k127_12036238_16	439481.Aboo_0139	6.432e-72	266.0	COG4906@1|root,arCOG00568@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2206
DPH1_k127_12036238_12	439481.Aboo_1442	6.089e-87	299.0	COG1819@1|root,arCOG01393@2157|Archaea,2Y65D@28890|Euryarchaeota,3F39J@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
DPH1_k127_12036238_10	1379698.RBG1_1C00001G0223	5.775e-93	313.0	COG0284@1|root,COG0284@2|Bacteria,2NP92@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
DPH1_k127_12036238_9	1123057.P872_05860	2.663e-93	318.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DPH1_k127_12036238_3	352165.HMPREF7215_1007	1.084e-139	454.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DPH1_k127_12036238_4	351160.RCIX1328	2.147e-128	422.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_12036238_2	269797.Mbar_A3653	3.105e-142	474.0	COG3408@1|root,arCOG03287@2157|Archaea,2XUJF@28890|Euryarchaeota,2N90H@224756|Methanomicrobia	224756|Methanomicrobia	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
DPH1_k127_12036238_0	247490.KSU1_C1645	8.542e-223	704.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase,YHS
DPH1_k127_12036238_5	439481.Aboo_1389	3.188e-110	372.0	COG0034@1|root,arCOG00093@2157|Archaea,2XSWJ@28890|Euryarchaeota,3F2FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
DPH1_k127_12036238_30	1380390.JIAT01000009_gene576	6.984e-09	67.0	COG1522@1|root,COG1522@2|Bacteria,2IFSQ@201174|Actinobacteria,4CSWD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_12036238_28	439235.Dalk_2302	3.786e-15	89.0	COG4870@1|root,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria	1224|Proteobacteria	O	PFAM Peptidase C1A, papain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_12036238_22	439481.Aboo_0416	4.62e-52	191.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,3F2MK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	ribG	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
DPH1_k127_12036238_18	1122217.KB899571_gene1096	3.433e-68	238.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,4H2TS@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
DPH1_k127_12036238_26	1041930.Mtc_1058	4.934e-23	110.0	COG4083@1|root,arCOG04471@2157|Archaea,2XTQZ@28890|Euryarchaeota,2N9VN@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
DPH1_k127_12036238_24	358823.DF19_38030	5.198e-38	151.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DPH1_k127_12036238_27	1293047.CBMA010000029_gene2027	3.012e-15	85.0	COG1183@1|root,arCOG00671@2157|Archaea,2XT0G@28890|Euryarchaeota,23TMI@183963|Halobacteria	183963|Halobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DPH1_k127_12036238_33	485917.Phep_1497	0.0003616	53.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DPH1_k127_12036238_20	673860.AciM339_0768	1.127e-57	206.0	COG1618@1|root,arCOG01034@2157|Archaea,2XX6U@28890|Euryarchaeota,3F2MF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
DPH1_k127_12036238_17	529709.PYCH_00880	3.014e-69	248.0	COG1867@1|root,arCOG01219@2157|Archaea,2XTUF@28890|Euryarchaeota,243GQ@183968|Thermococci	183968|Thermococci	J	Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups	trm1	GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
DPH1_k127_12036238_19	696369.KI912183_gene226	6.992e-59	213.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,261MS@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
DPH1_k127_12036238_7	555079.Toce_0685	1.013e-98	341.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DPH1_k127_12036238_15	370438.PTH_1695	1.018e-76	264.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,260JH@186807|Peptococcaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
DPH1_k127_12036238_25	370438.PTH_1694	2.99e-36	142.0	COG0375@1|root,COG0375@2|Bacteria,1TTZK@1239|Firmicutes,25PCK@186801|Clostridia,266A0@186807|Peptococcaceae	186801|Clostridia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
DPH1_k127_12036238_21	331113.SNE_A11040	1.571e-52	194.0	COG0229@1|root,COG0229@2|Bacteria,2JGD0@204428|Chlamydiae	204428|Chlamydiae	C	SelR domain	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DPH1_k127_12036238_1	1191523.MROS_1683	4.602e-145	467.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DPH1_k127_12036238_8	246194.CHY_1281	7.496e-94	315.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,42FCT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
DPH1_k127_12036238_11	247490.KSU1_C0826	5.184e-87	293.0	COG1691@1|root,COG1691@2|Bacteria,2IYZT@203682|Planctomycetes	203682|Planctomycetes	S	COG1691 NCAIR mutase (PurE)-related	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
DPH1_k127_12036238_14	515635.Dtur_1544	2.344e-77	266.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K06898,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
DPH1_k127_12036238_29	1031288.AXAA01000005_gene2065	1.34e-14	76.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes	1239|Firmicutes	D	cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
DPH1_k127_12036238_32	644281.MFS40622_0958	3.72e-06	50.0	COG1371@1|root,arCOG04055@2157|Archaea,2XXRX@28890|Euryarchaeota,23R02@183939|Methanococci	183939|Methanococci	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
DPH1_k127_12318570_0	1278304.JAFR01000010_gene883	9.764e-78	278.0	COG1055@1|root,COG1055@2|Bacteria	2|Bacteria	P	arsenite transmembrane transporter activity	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	iAF1260.b3502,iB21_1397.B21_03304,iBWG_1329.BWG_3192,iECBD_1354.ECBD_0238,iECB_1328.ECB_03351,iECDH10B_1368.ECDH10B_3678,iECDH1ME8569_1439.ECDH1ME8569_3381,iECD_1391.ECD_03351,iECH74115_1262.ECH74115_4851,iECIAI1_1343.ECIAI1_3649,iECO103_1326.ECO103_4229,iECO111_1330.ECO111_4311,iECO26_1355.ECO26_4590,iECSE_1348.ECSE_3768,iECSP_1301.ECSP_4482,iECs_1301.ECs4374,iETEC_1333.ETEC_3749,iEcDH1_1363.EcDH1_0212,iEcE24377_1341.EcE24377A_3985,iEcHS_1320.EcHS_A3704,iEcolC_1368.EcolC_0214,iG2583_1286.G2583_4228,iJO1366.b3502,iSFV_1184.SFV_3514,iSF_1195.SF3535,iS_1188.S4233,iUMNK88_1353.UMNK88_4279,iY75_1357.Y75_RS19690,iZ_1308.Z4904	ArsB,CitMHS
DPH1_k127_12318570_4	443254.Marpi_0639	3.091e-32	142.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,He_PIG,LVIVD,Laminin_G_3,Reprolysin_4,TSP_3
DPH1_k127_12318570_1	871968.DESME_01195	1.22e-44	168.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,26212@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DPH1_k127_12318570_2	565033.GACE_0520	3.614e-44	173.0	COG0697@1|root,arCOG00271@2157|Archaea,2Y159@28890|Euryarchaeota,246ME@183980|Archaeoglobi	183980|Archaeoglobi	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_12318570_3	868131.MSWAN_2340	8.473e-43	165.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUT0@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_12318570_8	1296415.JACC01000020_gene3777	1.259e-06	63.0	COG3291@1|root,COG4412@1|root,COG5297@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179,ko:K20276,ko:K21449	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	CARDB,CBM_2,CBM_3,Glyco_hydro_9,PKD,Peptidase_M30
DPH1_k127_12318570_6	1047013.AQSP01000122_gene2224	1.578e-09	71.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
DPH1_k127_12318570_7	868131.MSWAN_2369	8.183e-08	65.0	COG1520@1|root,COG3291@1|root,arCOG02492@2157|Archaea,arCOG02508@2157|Archaea	2157|Archaea	G	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3_5,Big_5,CHB_HEX_C_1,PKD,PQQ_3
DPH1_k127_12318570_9	980584.AFPB01000122_gene2437	0.0002804	50.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I3P5@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix ASNC type	lrp	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_12318570_5	868595.Desca_0411	5.937e-28	114.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
DPH1_k127_1236244_1	224325.AF_2316	4.899e-99	341.0	COG1964@1|root,arCOG00933@2157|Archaea,2XTMK@28890|Euryarchaeota,245R2@183980|Archaeoglobi	183980|Archaeoglobi	L	Radical SAM domain protein	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
DPH1_k127_1236244_10	644281.MFS40622_1163	3.677e-27	121.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota	28890|Euryarchaeota	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DPH1_k127_1236244_6	1173020.Cha6605_4114	3.249e-40	164.0	COG3751@1|root,COG3751@2|Bacteria,1G31S@1117|Cyanobacteria	1117|Cyanobacteria	O	SMART Prolyl 4-hydroxylase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
DPH1_k127_1236244_5	502025.Hoch_0807	4.027e-48	188.0	COG3751@1|root,COG3751@2|Bacteria,1PBT5@1224|Proteobacteria,4383D@68525|delta/epsilon subdivisions,2X3DD@28221|Deltaproteobacteria,2YVIF@29|Myxococcales	28221|Deltaproteobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1236244_9	661478.OP10G_3716	1.453e-29	130.0	COG5322@1|root,COG5322@2|Bacteria	2|Bacteria	GT	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3,Shikimate_DH
DPH1_k127_1236244_14	306281.AJLK01000121_gene29	2.194e-06	60.0	COG3287@1|root,COG3287@2|Bacteria,1G0HF@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
DPH1_k127_1236244_7	1150474.JQJI01000004_gene394	5.285e-39	152.0	COG0509@1|root,COG0509@2|Bacteria,2GD57@200918|Thermotogae	200918|Thermotogae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DPH1_k127_1236244_2	373903.Hore_23440	9.453e-91	311.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,3WBC4@53433|Halanaerobiales	186801|Clostridia	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DPH1_k127_1236244_3	634498.mru_1988	2.9e-52	192.0	COG0513@1|root,arCOG00078@2157|Archaea,2XTFM@28890|Euryarchaeota,23NY5@183925|Methanobacteria	183925|Methanobacteria	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
DPH1_k127_1236244_11	263820.PTO1199	1.372e-24	115.0	COG0142@1|root,arCOG01726@2157|Archaea,2XT85@28890|Euryarchaeota,241QG@183967|Thermoplasmata	183967|Thermoplasmata	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DPH1_k127_1236244_4	1298865.H978DRAFT_1289	1.813e-51	189.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,464RW@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
DPH1_k127_1236244_0	1236689.MMALV_00330	7.802e-162	514.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,3F2FH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DPH1_k127_1236244_12	351160.RCIX1696	4.178e-18	101.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1236244_16	999541.bgla_2g25650	0.0005692	43.0	COG3239@1|root,COG3239@2|Bacteria,1R42Z@1224|Proteobacteria,2VM1N@28216|Betaproteobacteria,1K5A7@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
DPH1_k127_1236244_13	945713.IALB_0843	1.224e-06	63.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
DPH1_k127_1236244_8	459349.CLOAM0442	3.967e-34	154.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
DPH1_k127_1236244_15	796620.VIBC2010_18134	1.116e-05	54.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1S5YS@1236|Gammaproteobacteria,1Y2NB@135623|Vibrionales	135623|Vibrionales	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_12374914_4	1123376.AUIU01000011_gene1053	9.713e-05	50.0	COG0716@1|root,COG0716@2|Bacteria,3J1FF@40117|Nitrospirae	40117|Nitrospirae	C	Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_5
DPH1_k127_12374914_2	1114856.C496_10953	4.584e-16	91.0	COG3548@1|root,arCOG04887@2157|Archaea,2XUMU@28890|Euryarchaeota,23UZ5@183963|Halobacteria	183963|Halobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
DPH1_k127_12374914_3	591019.Shell_1473	5.675e-12	74.0	COG2245@1|root,arCOG01644@2157|Archaea,2XRHI@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF996
DPH1_k127_12374914_1	386456.JQKN01000010_gene620	4.014e-16	85.0	COG4635@1|root,arCOG00524@2157|Archaea,2Y1YN@28890|Euryarchaeota	28890|Euryarchaeota	C	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
DPH1_k127_12374914_0	765420.OSCT_0887	1.471e-26	123.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
DPH1_k127_12374914_5	1033810.HLPCO_002908	0.0001177	55.0	COG3420@1|root,COG4932@1|root,COG5604@1|root,COG3420@2|Bacteria,COG4932@2|Bacteria,COG5604@2|Bacteria	2|Bacteria	DZ	domain, Protein	bhp	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	Beta_helix,DUF5011,Flg_new,Gram_pos_anchor,He_PIG,YSIRK_signal
DPH1_k127_12374914_6	1340493.JNIF01000003_gene4149	0.0009133	46.0	COG3386@1|root,COG4625@1|root,COG3386@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	57723|Acidobacteria	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
DPH1_k127_12391245_6	1047013.AQSP01000122_gene2224	4.349e-10	72.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
DPH1_k127_12391245_4	415426.Hbut_0158	5.711e-54	194.0	COG1838@1|root,arCOG04406@2157|Archaea,2XQ9V@28889|Crenarchaeota	28889|Crenarchaeota	C	Fe-S type, tartrate fumarate subfamily, beta	-	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
DPH1_k127_12391245_3	1343739.PAP_05865	2.155e-93	314.0	COG1951@1|root,arCOG04407@2157|Archaea,2XUQI@28890|Euryarchaeota,242SI@183968|Thermococci	183968|Thermococci	C	Fumarate hydratase	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
DPH1_k127_12391245_1	386456.JQKN01000002_gene2818	1.89e-273	854.0	COG0365@1|root,arCOG01529@2157|Archaea,2XTAB@28890|Euryarchaeota,23NWY@183925|Methanobacteria	183925|Methanobacteria	I	TIGRFAM Acetate-CoA ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DPH1_k127_12391245_5	673860.AciM339_0022	1.628e-23	113.0	COG1522@1|root,arCOG01580@2157|Archaea,arCOG01585@2157|Archaea,2Y6YT@28890|Euryarchaeota,3F2Y0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_12391245_0	56780.SYN_01409	9.325e-291	905.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
DPH1_k127_12391245_2	1128398.Curi_c28890	2.377e-178	567.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,267TT@186813|unclassified Clostridiales	186801|Clostridia	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DPH1_k127_12633_3	123214.PERMA_0937	7.972e-07	62.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_12633_1	945713.IALB_0147	2.867e-29	134.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
DPH1_k127_12633_0	1192034.CAP_8276	5.822e-111	386.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
DPH1_k127_12633_4	429009.Adeg_1130	0.0001268	53.0	COG3209@1|root,COG3209@2|Bacteria,1V8N1@1239|Firmicutes,24KAW@186801|Clostridia,42GJS@68295|Thermoanaerobacterales	186801|Clostridia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	TGFb_propeptide
DPH1_k127_12633_2	765420.OSCT_1113	2.11e-07	60.0	2DV40@1|root,33TY5@2|Bacteria,2GBS5@200795|Chloroflexi,375P0@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1631952_22	1042377.AFPJ01000034_gene2380	0.0002971	53.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1R3YZ@1224|Proteobacteria,1RY6I@1236|Gammaproteobacteria,46AA7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Chitinase C	-	-	3.2.1.14,3.2.1.202	ko:K01183,ko:K21606	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	CBM5,GH18	-	CBM_5_12_2,ChiC,Glyco_hydro_18
DPH1_k127_1631952_1	1220534.B655_0941	6.663e-164	528.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
DPH1_k127_1631952_20	1220534.B655_0937	6.764e-08	59.0	arCOG01917@1|root,arCOG01917@2157|Archaea	2157|Archaea	M	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3,zinc_ribbon_2
DPH1_k127_1631952_9	673860.AciM339_1412	3.027e-32	133.0	COG1386@1|root,arCOG02613@2157|Archaea,2XZ7Q@28890|Euryarchaeota,3F2S6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	TIGRFAM segregation and condensation protein B	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
DPH1_k127_1631952_10	1054217.TALC_00234	1.092e-29	130.0	COG1354@1|root,arCOG02610@2157|Archaea,2Y6XG@28890|Euryarchaeota,241WP@183967|Thermoplasmata	183967|Thermoplasmata	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	-
DPH1_k127_1631952_0	1054217.TALC_00233	2.316e-177	599.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,241K1@183967|Thermoplasmata	183967|Thermoplasmata	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DPH1_k127_1631952_14	1121889.AUDM01000002_gene448	1.04e-21	109.0	COG3210@1|root,COG4675@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DPH1_k127_1631952_13	192952.MM_3318	7.378e-22	111.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_1631952_16	1042877.GQS_04115	7.137e-15	85.0	COG3291@1|root,arCOG05839@1|root,arCOG02508@2157|Archaea,arCOG05839@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,PKD,Pilin_N,SdrD_B
DPH1_k127_1631952_4	1041930.Mtc_2262	4.037e-95	320.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT7Q@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_1631952_11	1041930.Mtc_2261	1.828e-28	128.0	COG1668@1|root,arCOG01470@2157|Archaea	2157|Archaea	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
DPH1_k127_1631952_6	1121335.Clst_1990	1.055e-77	273.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1VRTV@1239|Firmicutes,24H21@186801|Clostridia	186801|Clostridia	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DPH1_k127_1631952_2	391598.FBBAL38_09852	4.625e-124	418.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_1631952_3	391598.FBBAL38_09852	1.839e-119	405.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_1631952_8	289376.THEYE_A0577	1.889e-62	230.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DPH1_k127_1631952_7	1121335.Clst_1990	7.005e-77	271.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1VRTV@1239|Firmicutes,24H21@186801|Clostridia	186801|Clostridia	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DPH1_k127_1631952_21	1122973.KB904250_gene1253	0.0002654	53.0	COG4285@1|root,COG4285@2|Bacteria	2|Bacteria	S	Biotin-protein ligase, N terminal	CP_0643	-	-	-	-	-	-	-	-	-	-	-	BPL_N
DPH1_k127_1631952_15	268739.Nmlp_2650	2.563e-18	102.0	COG1361@1|root,COG1470@1|root,COG3291@1|root,arCOG03612@1|root,arCOG04500@1|root,arCOG07554@1|root,arCOG02081@2157|Archaea,arCOG02089@2157|Archaea,arCOG02510@2157|Archaea,arCOG03612@2157|Archaea,arCOG04500@2157|Archaea,arCOG07554@2157|Archaea,2XWGB@28890|Euryarchaeota,23UX2@183963|Halobacteria	183963|Halobacteria	M	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1631952_19	324057.Pjdr2_4093	5.162e-09	71.0	COG2247@1|root,COG2374@1|root,COG4733@1|root,COG5263@1|root,COG5520@1|root,COG2247@2|Bacteria,COG2374@2|Bacteria,COG4733@2|Bacteria,COG5263@2|Bacteria,COG5520@2|Bacteria,1UJ5H@1239|Firmicutes,4IT2G@91061|Bacilli,27785@186822|Paenibacillaceae	91061|Bacilli	E	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43,SLH,fn3
DPH1_k127_1631952_12	224325.AF_1413	5.334e-25	124.0	arCOG02499@1|root,arCOG02552@1|root,arCOG02499@2157|Archaea,arCOG02552@2157|Archaea	2157|Archaea	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,NosD,PKD
DPH1_k127_1631952_5	1121405.dsmv_3536	1.684e-78	267.0	2AEGW@1|root,314C3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1631952_23	509191.AEDB02000022_gene2922	0.000749	52.0	COG1520@1|root,COG3509@1|root,COG1520@2|Bacteria,COG3509@2|Bacteria,1VUN0@1239|Firmicutes	1239|Firmicutes	DZ	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_1631952_17	1379858.N508_00871	1.374e-13	83.0	COG0785@1|root,COG0785@2|Bacteria,2GEQS@200930|Deferribacteres	200930|Deferribacteres	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DPH1_k127_19461_41	37919.EP51_46855	0.0002769	49.0	COG3255@1|root,COG3255@2|Bacteria,2IHG7@201174|Actinobacteria,4G7SQ@85025|Nocardiaceae	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
DPH1_k127_19461_6	316067.Geob_0965	3.187e-102	357.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
DPH1_k127_19461_43	123214.PERMA_0937	0.0008517	52.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_19461_19	324602.Caur_3541	1.226e-47	191.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Arylsulfotran_2,Arylsulfotrans
DPH1_k127_19461_13	439481.Aboo_1400	3.945e-71	252.0	COG1506@1|root,arCOG01646@2157|Archaea	2157|Archaea	E	Peptidase S9 prolyl oligopeptidase active site	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abhydrolase_1
DPH1_k127_19461_35	386456.JQKN01000001_gene1666	8.422e-20	103.0	COG0784@1|root,COG3920@1|root,arCOG02348@1|root,arCOG02352@1|root,arCOG02335@2157|Archaea,arCOG02348@2157|Archaea,arCOG02352@2157|Archaea,arCOG06537@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_19461_8	386456.JQKN01000001_gene1847	5.505e-97	327.0	COG0281@1|root,arCOG01331@2157|Archaea,2XTRZ@28890|Euryarchaeota,23PGN@183925|Methanobacteria	183925|Methanobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	EF-hand_5,Peptidase_M48
DPH1_k127_19461_21	269797.Mbar_A0523	1.14e-44	164.0	arCOG05276@1|root,arCOG05276@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_excise
DPH1_k127_19461_40	937774.TEQUI_0673	0.0002762	52.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,3T2TH@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_19461_32	1262914.BN533_00736	1.775e-28	118.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,4H61W@909932|Negativicutes	909932|Negativicutes	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DPH1_k127_19461_28	351627.Csac_0112	1.455e-34	138.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,42GWU@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
DPH1_k127_19461_12	265072.Mfla_0784	6.362e-80	276.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,2KKPU@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DPH1_k127_19461_17	439481.Aboo_0227	1.506e-58	214.0	COG1650@1|root,arCOG01616@2157|Archaea,2XUM0@28890|Euryarchaeota,3F2M2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
DPH1_k127_19461_31	439481.Aboo_0455	1.192e-31	127.0	COG0350@1|root,COG1515@1|root,arCOG00929@2157|Archaea,arCOG02724@2157|Archaea,2XURE@28890|Euryarchaeota,3F2XY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	nfi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Endonuclease_5
DPH1_k127_19461_9	1379698.RBG1_1C00001G0171	2.557e-91	308.0	COG1235@1|root,COG1235@2|Bacteria,2NP81@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
DPH1_k127_19461_7	186497.PF1049	3.437e-99	333.0	COG1313@1|root,arCOG00934@2157|Archaea,2XUM6@28890|Euryarchaeota,242QN@183968|Thermococci	183968|Thermococci	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DPH1_k127_19461_10	744872.Spica_1727	3.241e-90	305.0	COG0095@1|root,COG0095@2|Bacteria,2J7CV@203691|Spirochaetes	203691|Spirochaetes	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
DPH1_k127_19461_37	1089553.Tph_c19540	3.771e-08	58.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia,42ET4@68295|Thermoanaerobacterales	186801|Clostridia	H	biotin lipoate A B protein ligase	lipM	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
DPH1_k127_19461_3	867903.ThesuDRAFT_01204	1.319e-104	347.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,2495Q@186801|Clostridia,3WD04@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
DPH1_k127_19461_34	795797.C497_13720	3.544e-23	113.0	COG1967@1|root,arCOG02177@2157|Archaea,2XT8V@28890|Euryarchaeota,23SFQ@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF63
DPH1_k127_19461_24	926560.KE387023_gene3745	4.457e-40	162.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.15	ko:K01365,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00537,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I42,Peptidase_C1
DPH1_k127_19461_4	1041930.Mtc_0013	2.001e-104	351.0	COG0371@1|root,arCOG00982@2157|Archaea,2XT0F@28890|Euryarchaeota,2N90F@224756|Methanomicrobia	224756|Methanomicrobia	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
DPH1_k127_19461_30	439481.Aboo_0537	2.315e-34	137.0	COG1860@1|root,arCOG04477@2157|Archaea,2XX8X@28890|Euryarchaeota,3F2TM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterised protein family (UPF0179)	-	-	-	ko:K09730	-	-	-	-	ko00000	-	-	-	UPF0179
DPH1_k127_19461_1	1122216.AUHW01000003_gene619	4.581e-150	484.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4H2F2@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DPH1_k127_19461_33	439481.Aboo_0398	6.366e-25	108.0	arCOG03678@1|root,arCOG03678@2157|Archaea,2XZ63@28890|Euryarchaeota,3F2RS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_19461_27	1459636.NTE_03124	5.375e-35	147.0	COG0524@1|root,arCOG00014@2157|Archaea	2157|Archaea	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB,Regulator_TrmB,TrmB
DPH1_k127_19461_5	604354.TSIB_1195	1.469e-102	348.0	COG1078@1|root,arCOG04430@2157|Archaea,2XUT7@28890|Euryarchaeota,2433G@183968|Thermococci	183968|Thermococci	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
DPH1_k127_19461_22	1094980.Mpsy_1303	8.074e-43	160.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2N9YG@224756|Methanomicrobia	224756|Methanomicrobia	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DPH1_k127_19461_36	198467.NP92_06060	1.459e-12	74.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,21WUB@150247|Anoxybacillus	91061|Bacilli	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DPH1_k127_19461_25	622312.ROSEINA2194_04439	6e-38	153.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
DPH1_k127_19461_29	368407.Memar_0689	1.706e-34	150.0	COG1541@1|root,arCOG02624@2157|Archaea,2XW5Z@28890|Euryarchaeota	28890|Euryarchaeota	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
DPH1_k127_19461_11	264732.Moth_0831	1.092e-87	306.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,42IC3@68295|Thermoanaerobacterales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DPH1_k127_19461_14	517417.Cpar_1106	1.571e-67	239.0	COG1194@1|root,COG1194@2|Bacteria,1FD5V@1090|Chlorobi	1090|Chlorobi	L	HhH-GPD family	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
DPH1_k127_19461_2	1305737.JAFX01000001_gene771	4.655e-138	445.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,47JCC@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DPH1_k127_19461_0	153721.MYP_1245	3.409e-197	622.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
DPH1_k127_19461_16	1047013.AQSP01000091_gene652	7.509e-63	220.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
DPH1_k127_19461_23	401053.AciPR4_3825	1.346e-42	171.0	COG0644@1|root,COG0644@2|Bacteria,3Y5JJ@57723|Acidobacteria,2JP4I@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DPH1_k127_19461_20	351160.RRC508	7.983e-46	171.0	COG5423@1|root,arCOG04361@2157|Archaea,2XXNK@28890|Euryarchaeota	28890|Euryarchaeota	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
DPH1_k127_19461_18	536227.CcarbDRAFT_1837	2.616e-52	190.0	COG1247@1|root,COG1247@2|Bacteria,1VCIC@1239|Firmicutes,24N1F@186801|Clostridia,36N5J@31979|Clostridiaceae	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
DPH1_k127_19461_38	368408.Tpen_0017	9.869e-07	57.0	arCOG02435@1|root,arCOG02435@2157|Archaea	2157|Archaea	F	deoxyribonucleoside 5'-monophosphate N-glycosidase activity	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	Nuc_deoxyrib_tr
DPH1_k127_19461_26	743836.AYNA01000104_gene2059	1.738e-35	149.0	COG1215@1|root,COG1215@2|Bacteria,1R8UT@1224|Proteobacteria,2TVQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
DPH1_k127_19461_15	1173022.Cri9333_2199	3.383e-66	237.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1G3WZ@1117|Cyanobacteria,1HDM6@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DPH1_k127_2111773_49	123214.PERMA_0937	8.881e-07	55.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_2111773_38	1123320.KB889668_gene3380	3.125e-19	99.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	3.4.11.5	ko:K01259,ko:K06889,ko:K21193	ko00330,ko01059,map00330,map01059	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6,DUF2048
DPH1_k127_2111773_32	529709.PYCH_04820	4.324e-32	136.0	arCOG11399@1|root,arCOG11399@2157|Archaea,2Y6N1@28890|Euryarchaeota,244XG@183968|Thermococci	183968|Thermococci	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
DPH1_k127_2111773_40	751944.HALDL1_01180	6.169e-19	96.0	COG5340@1|root,arCOG04793@2157|Archaea,2XVVB@28890|Euryarchaeota,23UHQ@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
DPH1_k127_2111773_46	933262.AXAM01000021_gene479	3.957e-10	73.0	COG1075@1|root,COG1404@1|root,COG2304@1|root,COG3507@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3507@2|Bacteria,1NDGA@1224|Proteobacteria,43DCN@68525|delta/epsilon subdivisions,2WRRD@28221|Deltaproteobacteria,2MME4@213118|Desulfobacterales	28221|Deltaproteobacteria	G	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
DPH1_k127_2111773_9	1047013.AQSP01000130_gene1853	1.131e-108	365.0	COG2887@1|root,COG2887@2|Bacteria,2NQTZ@2323|unclassified Bacteria	2|Bacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	FtsK_SpoIIIE,PDDEXK_1
DPH1_k127_2111773_31	706587.Desti_1486	5.901e-34	145.0	COG2267@1|root,COG2267@2|Bacteria,1RJ4X@1224|Proteobacteria,42WRI@68525|delta/epsilon subdivisions,2WRZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
DPH1_k127_2111773_34	439235.Dalk_2302	1.913e-25	124.0	COG4870@1|root,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria	1224|Proteobacteria	O	PFAM Peptidase C1A, papain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_2111773_30	192952.MM_3203	7.452e-37	159.0	COG4870@1|root,arCOG03991@1|root,arCOG03607@2157|Archaea,arCOG03991@2157|Archaea,2XWQ1@28890|Euryarchaeota	28890|Euryarchaeota	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_C1
DPH1_k127_2111773_12	322159.STER_0149	1.924e-99	338.0	COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HCTC@91061|Bacilli	91061|Bacilli	M	Chitin synthase	hasA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605,GO:0090609	2.4.1.212	ko:K00752	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Chitin_synth_2,Glycos_transf_2,PilZ
DPH1_k127_2111773_35	756067.MicvaDRAFT_5445	3.573e-24	118.0	COG0810@1|root,COG1404@1|root,COG2931@1|root,COG0810@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G3AC@1117|Cyanobacteria,1HE4V@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Peptidase C11, clostripain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_C11,VCBS
DPH1_k127_2111773_0	370438.PTH_2867	1.392e-266	831.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,2607A@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
DPH1_k127_2111773_42	304371.MCP_2098	2.066e-17	82.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota,2NA39@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2111773_5	1499967.BAYZ01000009_gene5343	8.738e-121	396.0	COG2008@1|root,COG2008@2|Bacteria,2NP02@2323|unclassified Bacteria	2|Bacteria	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DPH1_k127_2111773_51	1307436.PBF_14609	1.163e-05	56.0	COG0697@1|root,COG0697@2|Bacteria,1V0DI@1239|Firmicutes,4HD1I@91061|Bacilli,1ZQ3C@1386|Bacillus	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_2111773_47	304371.MCP_2089	2.573e-08	58.0	arCOG09498@1|root,arCOG09498@2157|Archaea,2Y5MP@28890|Euryarchaeota,2NBCR@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2111773_15	1220534.B655_1409	4.335e-86	290.0	COG2041@1|root,arCOG00266@2157|Archaea	2157|Archaea	P	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,Oxidored_molyb
DPH1_k127_2111773_28	1220534.B655_1311	4.751e-38	149.0	COG0500@1|root,arCOG02702@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DPH1_k127_2111773_50	1121019.AUMN01000006_gene3065	4.34e-06	59.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Malectin,PKD
DPH1_k127_2111773_22	1306406.ASHX01000001_gene4469	1.631e-65	244.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF11,PKD,PPC
DPH1_k127_2111773_36	1123508.JH636446_gene6313	2.243e-22	112.0	COG2931@1|root,COG3210@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,2J3HW@203682|Planctomycetes	203682|Planctomycetes	QU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2111773_37	647113.Metok_0976	2.336e-21	97.0	COG4818@1|root,arCOG04344@2157|Archaea,2Y0G5@28890|Euryarchaeota,23RV2@183939|Methanococci	183939|Methanococci	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
DPH1_k127_2111773_45	397948.Cmaq_1914	7.837e-12	72.0	arCOG06011@1|root,arCOG06011@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
DPH1_k127_2111773_33	1078085.HMPREF1210_02804	3.573e-26	112.0	COG5580@1|root,COG5580@2|Bacteria,1VXSU@1239|Firmicutes,4HXVJ@91061|Bacilli	91061|Bacilli	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DPH1_k127_2111773_44	1121272.KB903256_gene5552	6.636e-14	84.0	COG2133@1|root,COG3291@1|root,COG3507@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4D8ZK@85008|Micromonosporales	201174|Actinobacteria	G	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1349,GSDH,PKD,ThuA
DPH1_k127_2111773_26	459349.CLOAM0582	1.827e-44	177.0	COG1572@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	F5_F8_type_C,Glucosaminidase,SLH
DPH1_k127_2111773_27	391623.TERMP_00608	2.516e-38	151.0	COG2245@1|root,arCOG01644@2157|Archaea,2XY66@28890|Euryarchaeota,24464@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF996
DPH1_k127_2111773_48	138119.DSY4569	5.946e-08	66.0	COG4733@1|root,COG4733@2|Bacteria,1UID6@1239|Firmicutes,24BR3@186801|Clostridia,2679Z@186807|Peptococcaceae	186801|Clostridia	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_2111773_43	1047013.AQSP01000122_gene2223	1.027e-15	91.0	COG3291@1|root,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,CHU_C,FlgD_ig,Glyco_hydro_6,PKD,VCBS
DPH1_k127_2111773_20	696747.NIES39_O05150	2.683e-68	257.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,1G7CP@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DPH1_k127_2111773_19	633148.Tagg_0345	1.996e-68	245.0	COG0451@1|root,arCOG01369@2157|Archaea,2XRSX@28889|Crenarchaeota	28889|Crenarchaeota	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DPH1_k127_2111773_39	1150474.JQJI01000027_gene967	5.598e-19	102.0	COG1404@1|root,COG1404@2|Bacteria,2GCI9@200918|Thermotogae	200918|Thermotogae	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DPH1_k127_2111773_14	374847.Kcr_0638	2.743e-91	323.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DPH1_k127_2111773_13	374847.Kcr_0638	1.415e-95	327.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DPH1_k127_2111773_41	381764.Fnod_0028	4.814e-18	85.0	COG1278@1|root,COG1278@2|Bacteria,2GDFN@200918|Thermotogae	200918|Thermotogae	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DPH1_k127_2111773_10	439481.Aboo_0148	5.885e-107	355.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,3F37Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DPH1_k127_2111773_1	572546.Arcpr_1218	7.756e-159	517.0	COG1004@1|root,arCOG00253@2157|Archaea,2XTQY@28890|Euryarchaeota	28890|Euryarchaeota	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1119,iAF692.Mbar_A1120	Intein_splicing,LAGLIDADG_3,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DPH1_k127_2111773_8	269797.Mbar_A2905	6.952e-117	383.0	COG1210@1|root,arCOG00665@2157|Archaea,2XTI6@28890|Euryarchaeota,2NAD0@224756|Methanomicrobia	224756|Methanomicrobia	M	Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DPH1_k127_2111773_7	1382315.JPOI01000001_gene1129	9.77e-120	394.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HD4F@91061|Bacilli,1WGDJ@129337|Geobacillus	91061|Bacilli	E	DegT/DnrJ/EryC1/StrS aminotransferase family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DPH1_k127_2111773_21	314225.ELI_13350	1.194e-65	227.0	COG0110@1|root,COG0110@2|Bacteria,1RDCP@1224|Proteobacteria,2TWW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DPH1_k127_2111773_4	929556.Solca_3168	3.495e-140	453.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1IR57@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DPH1_k127_2111773_29	457396.CSBG_00504	4.445e-37	153.0	COG1215@1|root,COG1215@2|Bacteria,1U4ZW@1239|Firmicutes,25P1E@186801|Clostridia,36EAF@31979|Clostridiaceae	186801|Clostridia	M	Succinoglycan biosynthesis protein exoa	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DPH1_k127_2111773_23	456320.Mvol_0231	7.483e-56	210.0	COG0438@1|root,arCOG01410@2157|Archaea,2XYAQ@28890|Euryarchaeota,23RKZ@183939|Methanococci	183939|Methanococci	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
DPH1_k127_2111773_3	368407.Memar_1605	1.135e-141	458.0	COG0381@1|root,arCOG01392@2157|Archaea,2XU0B@28890|Euryarchaeota,2NANE@224756|Methanomicrobia	224756|Methanomicrobia	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DPH1_k127_2111773_16	386456.JQKN01000002_gene2744	3.633e-76	267.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota,23NSJ@183925|Methanobacteria	183925|Methanobacteria	S	PFAM Oxidoreductase	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DPH1_k127_2111773_17	589924.Ferp_2378	1.193e-69	244.0	COG0110@1|root,arCOG01848@2157|Archaea,2XWJM@28890|Euryarchaeota,2474T@183980|Archaeoglobi	183980|Archaeoglobi	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DPH1_k127_2111773_6	1220534.B655_1723	2.839e-120	396.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23NU5@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DPH1_k127_2111773_18	1234664.AMRO01000052_gene159	1.636e-68	250.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1WE58@129337|Geobacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DPH1_k127_2111773_2	267377.MMP1081	3.637e-155	497.0	COG0037@1|root,arCOG15275@2157|Archaea,2Y0EE@28890|Euryarchaeota,23RGF@183939|Methanococci	183939|Methanococci	D	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2111773_52	1219072.VHA01S_032_00240	2.533e-05	56.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	epsD	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754,ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DPH1_k127_2111773_11	523850.TON_1701	9.93e-100	335.0	COG1086@1|root,arCOG01375@2157|Archaea,2XV3Z@28890|Euryarchaeota	28890|Euryarchaeota	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
DPH1_k127_2111773_24	386456.JQKN01000003_gene384	9.094e-53	189.0	COG0110@1|root,arCOG01848@2157|Archaea,2XX2M@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DPH1_k127_2111773_25	273068.TTE0667	9.215e-45	165.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,42FQR@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
DPH1_k127_2168610_14	749927.AMED_1989	5.685e-05	54.0	COG3209@1|root,COG3209@2|Bacteria,2GP7Z@201174|Actinobacteria,4DXWA@85010|Pseudonocardiales	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PA14,RHS_repeat
DPH1_k127_2168610_6	439481.Aboo_0956	3.411e-60	215.0	COG0164@1|root,arCOG04121@2157|Archaea,2XWYC@28890|Euryarchaeota,3F2N8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DPH1_k127_2168610_1	634956.Geoth_3179	4.435e-127	418.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,1WE52@129337|Geobacillus	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
DPH1_k127_2168610_7	186497.PF1896	2.169e-49	185.0	COG2519@1|root,arCOG00978@2157|Archaea,2XTV7@28890|Euryarchaeota,2439X@183968|Thermococci	183968|Thermococci	J	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
DPH1_k127_2168610_4	673860.AciM339_0248	1.48e-92	315.0	COG1244@1|root,arCOG01360@2157|Archaea,2XT5Q@28890|Euryarchaeota,3F2I0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	Radical_SAM
DPH1_k127_2168610_2	1408433.JHXV01000002_gene442	5.144e-123	418.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_2168610_11	269797.Mbar_A1800	8.867e-15	88.0	COG1520@1|root,COG3291@1|root,arCOG02550@1|root,arCOG03991@1|root,arCOG02482@2157|Archaea,arCOG02510@2157|Archaea,arCOG02550@2157|Archaea,arCOG03991@2157|Archaea,2XUI1@28890|Euryarchaeota,2NBKW@224756|Methanomicrobia	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM_6,DUF3344,NosD,PKD,PQQ_2,PQQ_3,Pkinase
DPH1_k127_2168610_0	1094980.Mpsy_2683	1.345e-140	462.0	COG0172@1|root,arCOG00403@2157|Archaea,2XUK2@28890|Euryarchaeota,2N9B1@224756|Methanomicrobia	224756|Methanomicrobia	J	able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A2126	-
DPH1_k127_2168610_10	1120950.KB892752_gene6154	1.486e-15	90.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4DP00@85009|Propionibacteriales	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,Malectin,PKD
DPH1_k127_2168610_9	1121448.DGI_2194	9.287e-27	126.0	COG4870@1|root,COG4870@2|Bacteria,1RJ0M@1224|Proteobacteria,42V4Z@68525|delta/epsilon subdivisions,2WRZX@28221|Deltaproteobacteria,2MG61@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_2168610_13	439481.Aboo_0449	1.38e-05	49.0	arCOG01354@1|root,arCOG01354@2157|Archaea,2Y76E@28890|Euryarchaeota,3F3GU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2168610_5	1236689.MMALV_15590	7.414e-70	254.0	COG0608@1|root,arCOG00427@2157|Archaea,2XW5A@28890|Euryarchaeota,3F2M1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHH,DHHA1
DPH1_k127_2168610_8	521011.Mpal_2661	2.985e-44	165.0	COG0184@1|root,arCOG04185@2157|Archaea,2XWKV@28890|Euryarchaeota,2N9S2@224756|Methanomicrobia	224756|Methanomicrobia	J	ribosomal protein S15	rps15	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
DPH1_k127_2168610_3	391598.FBBAL38_09852	7.719e-123	415.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_2168610_12	519989.ECTPHS_00520	5.825e-11	62.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1WW6E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
DPH1_k127_2195967_2	1047013.AQSP01000140_gene2452	2.957e-175	556.0	COG0473@1|root,COG0473@2|Bacteria,2NNUM@2323|unclassified Bacteria	2|Bacteria	CE	Isocitrate/isopropylmalate dehydrogenase	dlpA	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh,MoCF_biosynth,RraA-like
DPH1_k127_2195967_4	439481.Aboo_0781	7.128e-94	318.0	COG1469@1|root,arCOG04301@2157|Archaea,2XT11@28890|Euryarchaeota,3F2JX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin	mptA	GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682	3.5.4.39	ko:K17488	ko00790,map00790	-	R10348	RC02504,RC03131	ko00000,ko00001,ko01000	-	-	-	GCHY-1
DPH1_k127_2195967_9	573063.Metin_1110	1.328e-34	142.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota,23Q8P@183939|Methanococci	183939|Methanococci	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB2	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_2195967_8	269797.Mbar_A0122	3.873e-37	143.0	COG0735@1|root,arCOG01868@2157|Archaea,2Y6FR@28890|Euryarchaeota,2NAYJ@224756|Methanomicrobia	224756|Methanomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DPH1_k127_2195967_0	485916.Dtox_0871	0.0	1272.0	COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,24DM7@186801|Clostridia,260RF@186807|Peptococcaceae	186801|Clostridia	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
DPH1_k127_2195967_11	515635.Dtur_0534	7.009e-22	98.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
DPH1_k127_2195967_10	580327.Tthe_2016	4.233e-34	134.0	COG1342@1|root,COG1342@2|Bacteria,1V5RE@1239|Firmicutes,25CFP@186801|Clostridia,42GP4@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
DPH1_k127_2195967_5	269797.Mbar_A0634	7.176e-93	312.0	COG0489@1|root,arCOG00585@2157|Archaea,2XTU2@28890|Euryarchaeota,2N9IC@224756|Methanomicrobia	224756|Methanomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
DPH1_k127_2195967_6	521011.Mpal_1669	3.343e-68	240.0	COG1321@1|root,arCOG02099@2157|Archaea,2XSWC@28890|Euryarchaeota,2N9TX@224756|Methanomicrobia	224756|Methanomicrobia	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DPH1_k127_2195967_1	521011.Mpal_1668	2.033e-193	622.0	COG0370@1|root,arCOG00359@2157|Archaea,2XU46@28890|Euryarchaeota,2N913@224756|Methanomicrobia	224756|Methanomicrobia	P	Ferrous iron transport B domain protein	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
DPH1_k127_2195967_3	331678.Cphamn1_0208	3.226e-103	345.0	COG0502@1|root,COG0502@2|Bacteria,1FD7J@1090|Chlorobi	1090|Chlorobi	H	PFAM Radical SAM domain protein	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DPH1_k127_2195967_14	1120925.F941_01066	0.0002265	52.0	2C2IF@1|root,32RAJ@2|Bacteria,1RHK0@1224|Proteobacteria,1S89N@1236|Gammaproteobacteria,3NIGM@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2195967_7	186497.PF1102	3.303e-63	230.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2435A@183968|Thermococci	183968|Thermococci	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DPH1_k127_2195967_12	419665.Maeo_0966	6.96e-19	93.0	COG2210@1|root,arCOG02064@2157|Archaea,2XT1G@28890|Euryarchaeota	28890|Euryarchaeota	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
DPH1_k127_2195967_13	1400520.LFAB_17155	4.07e-09	70.0	COG5621@1|root,COG5621@2|Bacteria,1VE5E@1239|Firmicutes,4HUMD@91061|Bacilli	91061|Bacilli	S	CrtC N-terminal lipocalin domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC
DPH1_k127_2377383_0	1220534.B655_0707	1.734e-31	124.0	arCOG12322@1|root,arCOG12322@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2377383_1	497964.CfE428DRAFT_3274	3.744e-06	61.0	COG0737@1|root,COG2374@1|root,COG4733@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,COG4733@2|Bacteria,46VVX@74201|Verrucomicrobia	74201|Verrucomicrobia	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
DPH1_k127_2840086_3	1163617.SCD_n00353	3.665e-06	57.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,2VIYN@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Periplasmic copper-binding	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_2840086_4	1242864.D187_006025	4.061e-05	51.0	COG1404@1|root,COG3291@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YZ9E@29|Myxococcales	28221|Deltaproteobacteria	OQ	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
DPH1_k127_2840086_2	243164.DET1295	8.582e-08	64.0	COG4188@1|root,COG4188@2|Bacteria,2G7HR@200795|Chloroflexi,34CZE@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2840086_0	1499967.BAYZ01000045_gene2673	7.231e-58	217.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DPH1_k127_2840086_1	593117.TGAM_0982	1.137e-16	92.0	COG5306@1|root,arCOG03264@1|root,arCOG06661@1|root,arCOG03264@2157|Archaea,arCOG03512@2157|Archaea,arCOG06661@2157|Archaea	2157|Archaea	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,DUF5122,Laminin_G_3,PEGA
DPH1_k127_3066447_0	670487.Ocepr_0436	1.59e-05	58.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DPH1_k127_3141710_8	351160.RRC361	1.4e-127	426.0	COG1032@1|root,arCOG04984@2157|Archaea,2XUS3@28890|Euryarchaeota,2N97H@224756|Methanomicrobia	224756|Methanomicrobia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
DPH1_k127_3141710_39	406327.Mevan_0374	5.572e-33	138.0	COG0496@1|root,arCOG02303@2157|Archaea,2XT5R@28890|Euryarchaeota,23Q7W@183939|Methanococci	183939|Methanococci	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
DPH1_k127_3141710_17	545243.BAEV01000034_gene1732	4.34e-81	284.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,248J3@186801|Clostridia,36F50@31979|Clostridiaceae	186801|Clostridia	P	calcium proton exchanger	cax	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
DPH1_k127_3141710_36	1220534.B655_0812	3.211e-45	175.0	COG0301@1|root,arCOG00038@2157|Archaea,2XUHM@28890|Euryarchaeota,23NP8@183925|Methanobacteria	183925|Methanobacteria	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
DPH1_k127_3141710_32	342949.PNA2_1972	1.885e-52	198.0	COG1893@1|root,arCOG04139@2157|Archaea,2XTBD@28890|Euryarchaeota,243P9@183968|Thermococci	183968|Thermococci	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DPH1_k127_3141710_56	1122194.AUHU01000003_gene2278	4.884e-05	56.0	COG3866@1|root,COG3866@2|Bacteria,1MUT3@1224|Proteobacteria,1RT2J@1236|Gammaproteobacteria,469JQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3141710_9	264732.Moth_1954	3.077e-120	394.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,42FFI@68295|Thermoanaerobacterales	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	gyaR	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DPH1_k127_3141710_22	439481.Aboo_0029	1.03e-66	234.0	COG2220@1|root,arCOG00497@2157|Archaea,2XZBG@28890|Euryarchaeota,3F2Q1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
DPH1_k127_3141710_30	1236689.MMALV_00300	4.057e-58	215.0	COG1676@1|root,arCOG01701@2157|Archaea,2XTKB@28890|Euryarchaeota,3F2U2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	tRNA intron endonuclease, catalytic C-terminal domain	endA	GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
DPH1_k127_3141710_16	1343739.PAP_09730	1.56e-88	317.0	COG1750@1|root,arCOG01937@2157|Archaea,2XUEB@28890|Euryarchaeota,242IS@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S16 family	-	-	-	ko:K06870	-	-	-	-	ko00000	-	-	-	Lon_C
DPH1_k127_3141710_5	644281.MFS40622_0856	5.263e-185	597.0	COG5016@1|root,arCOG02095@2157|Archaea,2XV3W@28890|Euryarchaeota,23Q4T@183939|Methanococci	183939|Methanococci	C	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
DPH1_k127_3141710_6	456320.Mvol_1721	1.327e-174	559.0	COG0439@1|root,arCOG01590@2157|Archaea,2Y8CM@28890|Euryarchaeota,23QDY@183939|Methanococci	183939|Methanococci	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	pycA	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DPH1_k127_3141710_31	1094980.Mpsy_0928	2.212e-55	203.0	COG0340@1|root,COG2512@1|root,arCOG00374@2157|Archaea,arCOG01940@2157|Archaea,2XSZ5@28890|Euryarchaeota,2N982@224756|Methanomicrobia	224756|Methanomicrobia	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
DPH1_k127_3141710_46	387631.Asulf_00714	5.268e-20	93.0	COG1917@1|root,arCOG02999@2157|Archaea	2157|Archaea	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DPH1_k127_3141710_38	1499967.BAYZ01000076_gene805	5.061e-38	148.0	2DS8H@1|root,32USH@2|Bacteria	2|Bacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
DPH1_k127_3141710_12	96561.Dole_2139	3.221e-97	346.0	COG1520@1|root,COG3325@1|root,COG4870@1|root,COG1520@2|Bacteria,COG3325@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,DUF4849,PQQ_2,PQQ_3
DPH1_k127_3141710_54	671143.DAMO_1635	5.157e-06	58.0	COG0392@1|root,COG0392@2|Bacteria,2NPJC@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DPH1_k127_3141710_24	373903.Hore_18740	4.491e-65	229.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,25C2R@186801|Clostridia,3WCAD@53433|Halanaerobiales	186801|Clostridia	P	amino acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
DPH1_k127_3141710_13	1304875.JAFZ01000001_gene755	5.084e-95	320.0	COG1126@1|root,COG1126@2|Bacteria,3TAKG@508458|Synergistetes	508458|Synergistetes	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
DPH1_k127_3141710_29	403833.Pmob_1657	3.86e-58	209.0	COG0765@1|root,COG0765@2|Bacteria,2GCTA@200918|Thermotogae	200918|Thermotogae	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
DPH1_k127_3141710_28	593117.TGAM_0091	6.225e-59	213.0	COG0834@1|root,arCOG01799@2157|Archaea,2XUEH@28890|Euryarchaeota,244ZU@183968|Thermococci	183968|Thermococci	E	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
DPH1_k127_3141710_41	186497.PF1588	2.806e-31	132.0	COG2428@1|root,arCOG00968@2157|Archaea,2XVH8@28890|Euryarchaeota,242IZ@183968|Thermococci	183968|Thermococci	S	Predicted SAM-dependent RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_Me_trans
DPH1_k127_3141710_34	293826.Amet_1439	4.816e-51	194.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12,2.7.11.1,3.6.4.13	ko:K00627,ko:K03310,ko:K03578,ko:K12132	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko01001	2.A.25	-	-	2-oxoacid_dh,Biotin_lipoyl
DPH1_k127_3141710_19	1007103.AFHW01000032_gene2246	2.06e-78	269.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
DPH1_k127_3141710_15	945713.IALB_2039	4.796e-94	345.0	COG1361@1|root,COG1520@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Cohesin,DUF11,Peptidase_S8,SBBP,SLH,VCBS
DPH1_k127_3141710_51	118173.KB235914_gene1238	2.496e-13	78.0	COG0071@1|root,COG0071@2|Bacteria,1G5PX@1117|Cyanobacteria,1HAZK@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DPH1_k127_3141710_4	909663.KI867150_gene2237	5.49e-194	616.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MQ6P@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DPH1_k127_3141710_52	1163730.FFONT_0815	3.686e-11	75.0	COG0778@1|root,arCOG00288@2157|Archaea,2XQMS@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_3141710_49	999630.TUZN_1264	1.782e-16	92.0	COG0778@1|root,arCOG00288@2157|Archaea,2XQMS@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_3141710_2	391623.TERMP_00208	8.41e-247	777.0	COG1274@1|root,arCOG05865@2157|Archaea,2XUU1@28890|Euryarchaeota,24380@183968|Thermococci	183968|Thermococci	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
DPH1_k127_3141710_37	760568.Desku_2757	8.747e-44	166.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,26212@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DPH1_k127_3141710_55	456320.Mvol_0262	2.286e-05	55.0	COG1800@1|root,COG3420@1|root,arCOG02519@2157|Archaea,arCOG03419@2157|Archaea,2XVXJ@28890|Euryarchaeota,23QIG@183939|Methanococci	183939|Methanococci	P	APHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,S_layer_C
DPH1_k127_3141710_33	1163730.FFONT_0663	2.969e-51	190.0	COG5014@1|root,arCOG05120@2157|Archaea,2XPWW@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
DPH1_k127_3141710_43	344747.PM8797T_04585	3.111e-28	129.0	COG4927@1|root,COG4927@2|Bacteria,2IYD9@203682|Planctomycetes	203682|Planctomycetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
DPH1_k127_3141710_35	1459636.NTE_00463	2.415e-48	184.0	COG3177@1|root,arCOG03112@2157|Archaea	2157|Archaea	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
DPH1_k127_3141710_53	1128421.JAGA01000003_gene3303	1.29e-10	75.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	isp	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	PP2C_2
DPH1_k127_3141710_14	1157490.EL26_04335	5.145e-95	342.0	COG1502@1|root,COG2356@1|root,COG1502@2|Bacteria,COG2356@2|Bacteria	2|Bacteria	L	deoxyribonuclease I activity	-	-	-	ko:K06131,ko:K06915	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	CARDB,F5_F8_type_C,Helicase_C,LTD,MAM,PLDc_2,Peptidase_S8,Reprolysin_4,ResIII,fn3
DPH1_k127_3141710_44	1191523.MROS_0478	7.529e-24	113.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	Rhomboid
DPH1_k127_3141710_27	192952.MM_0909	6.003e-59	215.0	COG3389@1|root,arCOG04463@2157|Archaea,2XSZT@28890|Euryarchaeota,2N9I2@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART Peptidase A22, presenilin signal peptide	-	-	-	-	-	-	-	-	-	-	-	-	SPP
DPH1_k127_3141710_47	1121288.AULL01000013_gene1683	5.759e-19	100.0	COG3227@1|root,COG3227@2|Bacteria,4PM0G@976|Bacteroidetes,1IJI5@117743|Flavobacteriia,3ZSCE@59732|Chryseobacterium	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3141710_7	760568.Desku_0544	6.655e-153	494.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,260F0@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17,4.1.99.23	ko:K03147,ko:K22465	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
DPH1_k127_3141710_11	351160.RCIX1121	3.911e-108	371.0	COG1311@1|root,arCOG04455@2157|Archaea,2XSUG@28890|Euryarchaeota,2N96N@224756|Methanomicrobia	224756|Methanomicrobia	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B,Metallophos,tRNA_anti-codon
DPH1_k127_3141710_0	573063.Metin_1333	0.0	1103.0	COG1933@1|root,arCOG03147@2157|Archaea,arCOG04447@2157|Archaea,2XU5S@28890|Euryarchaeota,23Q0E@183939|Methanococci	183939|Methanococci	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Intein_splicing,LAGLIDADG_3,PolC_DP2
DPH1_k127_3141710_3	309800.C498_19354	1.433e-200	648.0	COG1241@1|root,arCOG00439@2157|Archaea,2XT5D@28890|Euryarchaeota,23SII@183963|Halobacteria	183963|Halobacteria	L	ATPase involved in replication control, Cdc46 Mcm family	mcm	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	HTH_3,HTH_31,Intein_splicing,LAGLIDADG_3,MCM,MCM_N,MCM_OB
DPH1_k127_3141710_1	439481.Aboo_0072	1.331e-314	979.0	COG0480@1|root,arCOG01559@2157|Archaea,2XUMQ@28890|Euryarchaeota,3F2GN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DPH1_k127_3141710_23	1236689.MMALV_03250	3.639e-65	228.0	COG0049@1|root,arCOG04254@2157|Archaea,2XTDC@28890|Euryarchaeota,3F2JI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DPH1_k127_3141710_26	439481.Aboo_0070	6.468e-63	218.0	COG0048@1|root,arCOG04255@2157|Archaea,2XX4A@28890|Euryarchaeota,3F2K0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DPH1_k127_3141710_45	575590.HMPREF0156_00095	1.136e-21	111.0	COG1404@1|root,COG2957@1|root,COG1404@2|Bacteria,COG2957@2|Bacteria,4NJ5R@976|Bacteroidetes	976|Bacteroidetes	E	cysteine-type endopeptidase activity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37	ko:K08589	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DPH1_k127_3141710_42	246969.TAM4_431	2.708e-29	120.0	COG2058@1|root,arCOG04287@2157|Archaea,2XYQ9@28890|Euryarchaeota,244BE@183968|Thermococci	183968|Thermococci	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	-	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
DPH1_k127_3141710_18	1236689.MMALV_00500	4.594e-80	276.0	COG0244@1|root,arCOG04288@2157|Archaea,2XU7C@28890|Euryarchaeota,3F2JW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s,Ribosomal_L10
DPH1_k127_3141710_21	439481.Aboo_0862	3.376e-69	240.0	COG0081@1|root,arCOG04289@2157|Archaea,2XTJF@28890|Euryarchaeota,3F2IX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DPH1_k127_3141710_25	1041930.Mtc_0282	3.162e-63	228.0	COG1395@1|root,arCOG04152@2157|Archaea,2XTMG@28890|Euryarchaeota,2N98I@224756|Methanomicrobia	224756|Methanomicrobia	K	HTH-type transcriptional regulatory protein	-	-	-	ko:K07728	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
DPH1_k127_3141710_10	439481.Aboo_0928	1.054e-118	396.0	COG1571@1|root,arCOG01115@2157|Archaea,2XTGD@28890|Euryarchaeota,3F2IS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743,tRNA_anti-codon
DPH1_k127_3141710_48	439235.Dalk_3341	3.784e-17	93.0	COG5621@1|root,COG5621@2|Bacteria,1N77M@1224|Proteobacteria	1224|Proteobacteria	S	secreted hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3141710_20	304371.MCP_0932	8.534e-70	239.0	arCOG12320@1|root,arCOG12320@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3141710_40	1499967.BAYZ01000080_gene926	4.771e-32	142.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DPH1_k127_3141710_50	1104324.P186_0370	6.149e-15	79.0	COG3373@1|root,arCOG03422@2157|Archaea	2157|Archaea	S	Winged helix DNA-binding domain (DUF1495)	-	-	-	ko:K09745	-	-	-	-	ko00000	-	-	-	DUF1495
DPH1_k127_3221074_17	1347392.CCEZ01000049_gene1377	1.62e-13	71.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,36EU1@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase	bdhA	GO:0003674,GO:0003824,GO:0004022,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	ko:K00100,ko:K19955	ko00650,ko01120,map00650,map01120	-	R03544,R03545	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
DPH1_k127_3221074_7	439481.Aboo_0325	3.699e-52	205.0	COG0475@1|root,arCOG01954@2157|Archaea,2XV51@28890|Euryarchaeota,3F2RA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DPH1_k127_3221074_20	1211814.CAPG01000078_gene3691	9.58e-05	51.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,1ZBNZ@1386|Bacillus	91061|Bacilli	S	Acetoin utilization protein AcuB	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
DPH1_k127_3221074_11	67593.Physo144483	1.272e-25	124.0	KOG2649@1|root,KOG2649@2759|Eukaryota,3QA8F@4776|Peronosporales	4776|Peronosporales	S	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DPH1_k127_3221074_14	1455608.JDTH01000001_gene2953	8.162e-18	90.0	COG1617@1|root,arCOG02197@2157|Archaea,2XXRY@28890|Euryarchaeota,23W8H@183963|Halobacteria	183963|Halobacteria	S	KEOPS complex Cgi121-like subunit	cgi121	-	-	ko:K09119	-	-	-	-	ko00000,ko03016	-	-	-	CGI-121
DPH1_k127_3221074_0	351160.RCIX575	2.597e-184	600.0	COG1204@1|root,arCOG00553@2157|Archaea,2XSV4@28890|Euryarchaeota,2N9A8@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
DPH1_k127_3221074_16	1379698.RBG1_1C00001G1780	2.059e-16	82.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
DPH1_k127_3221074_8	439481.Aboo_0003	1.917e-50	181.0	COG0231@1|root,arCOG04277@2157|Archaea,2XX3E@28890|Euryarchaeota,3F2PU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	EFP_N,eIF-5a
DPH1_k127_3221074_3	1041930.Mtc_1947	1.812e-69	245.0	COG0010@1|root,arCOG01700@2157|Archaea,2XTEP@28890|Euryarchaeota,2N9E1@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DPH1_k127_3221074_21	269797.Mbar_A1941	0.000467	52.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,2NB2Q@224756|Methanomicrobia	224756|Methanomicrobia	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DPH1_k127_3221074_1	439481.Aboo_1116	2.772e-143	468.0	COG0608@1|root,arCOG00427@2157|Archaea,2XT8Y@28890|Euryarchaeota,3F2FV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	recJ	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
DPH1_k127_3221074_15	1121405.dsmv_2012	2.702e-17	84.0	COG1036@1|root,COG1036@2|Bacteria	2|Bacteria	C	dihydromethanopterin reductase activity	gltD	-	1.2.7.3,1.97.1.9	ko:K00176,ko:K06411,ko:K12527	ko00020,ko00450,ko00720,ko01100,ko01120,ko01200,map00020,map00450,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197,R07229	RC00004,RC02420,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,Flavoprotein,Pyr_redox_2,Pyr_redox_3
DPH1_k127_3221074_9	368407.Memar_1021	1.926e-47	173.0	COG0454@1|root,arCOG00839@2157|Archaea,2Y20T@28890|Euryarchaeota,2NA2S@224756|Methanomicrobia	224756|Methanomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
DPH1_k127_3221074_2	521011.Mpal_2109	6.726e-79	273.0	COG4866@1|root,arCOG05191@2157|Archaea,2Y2YS@28890|Euryarchaeota,2NADR@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
DPH1_k127_3221074_22	981383.AEWH01000010_gene3821	0.0005415	48.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH,HNH_5
DPH1_k127_3221074_13	698769.JFBD01000029_gene1313	4.109e-18	94.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HIFA@91061|Bacilli,4C6W7@84406|Virgibacillus	91061|Bacilli	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DPH1_k127_3221074_4	1499967.BAYZ01000045_gene2673	5.648e-65	238.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DPH1_k127_3221074_6	1047013.AQSP01000119_gene1318	3.087e-62	220.0	COG4843@1|root,COG4843@2|Bacteria,2NPKB@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
DPH1_k127_3221074_5	1236689.MMALV_03010	1.007e-63	226.0	COG0638@1|root,arCOG00971@2157|Archaea,2XUKA@28890|Euryarchaeota,3F2G0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
DPH1_k127_3221074_18	374847.Kcr_1508	1.594e-08	59.0	COG1400@1|root,arCOG01217@2157|Archaea	2157|Archaea	J	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP	srp19	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
DPH1_k127_3221074_10	1220534.B655_2348	2.645e-35	139.0	COG2007@1|root,arCOG04154@2157|Archaea,2XYXX@28890|Euryarchaeota,23P4U@183925|Methanobacteria	183925|Methanobacteria	J	Ribosomal protein S8e	rps8e	-	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
DPH1_k127_3221074_19	215803.DB30_3800	1.281e-07	62.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,430Q8@68525|delta/epsilon subdivisions,2WVYQ@28221|Deltaproteobacteria,2YU06@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
DPH1_k127_3221074_12	1262449.CP6013_0770	1.608e-21	104.0	COG0457@1|root,COG3266@1|root,COG4676@1|root,COG4870@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,COG4676@2|Bacteria,COG4870@2|Bacteria,1VDA3@1239|Firmicutes	1239|Firmicutes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Flg_new,TPR_19
DPH1_k127_3370612_2	1158318.ATXC01000001_gene377	4.379e-10	64.0	COG0177@1|root,COG0177@2|Bacteria,2G3TX@200783|Aquificae	200783|Aquificae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DPH1_k127_3370612_1	386456.JQKN01000011_gene795	1.202e-28	117.0	COG0640@1|root,arCOG00731@2157|Archaea,2XYSK@28890|Euryarchaeota	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DPH1_k127_3370612_3	1313421.JHBV01000007_gene4246	3.973e-07	63.0	COG4249@1|root,COG4642@1|root,COG4249@2|Bacteria,COG4642@2|Bacteria,4NKYQ@976|Bacteroidetes,1IZAN@117747|Sphingobacteriia	976|Bacteroidetes	L	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	MORN,Peptidase_C14
DPH1_k127_3370612_0	436308.Nmar_0594	2.428e-54	203.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DPH1_k127_3954318_0	697303.Thewi_1722	2.33e-27	125.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
DPH1_k127_3954318_1	1445613.JALM01000051_gene4096	2.003e-10	72.0	COG1305@1|root,COG1305@2|Bacteria,2GMGI@201174|Actinobacteria,4E2TE@85010|Pseudonocardiales	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DPH1_k127_3954318_2	1179155.CF67_03021	5.855e-09	66.0	COG1541@1|root,COG1541@2|Bacteria,1NR5G@1224|Proteobacteria,1S1JA@1236|Gammaproteobacteria,1XUTW@135623|Vibrionales	135623|Vibrionales	H	Acyl-protein synthetase, LuxE	luxE	-	6.2.1.19	ko:K06046	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	LuxE
DPH1_k127_433662_3	485914.Hmuk_2921	1.176e-19	98.0	COG3979@1|root,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PKD
DPH1_k127_433662_2	1191523.MROS_1311	3.529e-27	128.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.1.3.1	ko:K01113,ko:K20276	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF11,Gram_pos_anchor
DPH1_k127_433662_4	1198114.AciX9_2489	1.323e-14	87.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	wcoG	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,PKD
DPH1_k127_433662_0	877455.Metbo_0860	3.772e-117	389.0	COG0726@1|root,arCOG02878@2157|Archaea	2157|Archaea	G	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DPH1_k127_433662_1	877455.Metbo_0861	1.521e-33	138.0	COG1541@1|root,arCOG02624@2157|Archaea,2XY74@28890|Euryarchaeota	28890|Euryarchaeota	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
DPH1_k127_4582555_13	143224.JQMD01000002_gene407	0.000148	51.0	COG1522@1|root,COG1522@2|Bacteria,4NNH2@976|Bacteroidetes,1I2AJ@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	lrp	-	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_4582555_8	351160.RCIX1696	5.346e-20	107.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4582555_9	309807.SRU_2299	2.738e-16	94.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FKAM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DPH1_k127_4582555_5	459349.CLOAM0442	4.264e-32	147.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
DPH1_k127_4582555_10	519442.Huta_2764	8.085e-15	88.0	arCOG02916@1|root,arCOG07781@1|root,arCOG02916@2157|Archaea,arCOG07781@2157|Archaea,2XUVP@28890|Euryarchaeota,23UBC@183963|Halobacteria	183963|Halobacteria	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_4582555_3	1192034.CAP_8277	2.137e-111	383.0	COG3266@1|root,COG3266@2|Bacteria,1QZBM@1224|Proteobacteria,42TG7@68525|delta/epsilon subdivisions,2WQPM@28221|Deltaproteobacteria,2Z3I2@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
DPH1_k127_4582555_4	925409.KI911562_gene2345	3.278e-67	233.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DPH1_k127_4582555_11	386456.JQKN01000004_gene169	3.247e-10	64.0	COG2002@1|root,arCOG00822@2157|Archaea,2Y5A3@28890|Euryarchaeota	28890|Euryarchaeota	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
DPH1_k127_4582555_2	1041930.Mtc_2047	2.535e-113	377.0	COG1131@1|root,arCOG00196@2157|Archaea,2Y7M5@28890|Euryarchaeota,2NBN9@224756|Methanomicrobia	224756|Methanomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_4582555_1	1041930.Mtc_2048	1.617e-114	381.0	COG0842@1|root,arCOG01463@2157|Archaea,2XVQJ@28890|Euryarchaeota,2NB7X@224756|Methanomicrobia	224756|Methanomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DPH1_k127_4582555_7	1127692.HMPREF9075_00738	5.286e-23	111.0	COG3391@1|root,COG4935@1|root,COG5276@1|root,COG3391@2|Bacteria,COG4935@2|Bacteria,COG5276@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,1ER48@1016|Capnocytophaga	976|Bacteroidetes	O	Thrombospondin type 3	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
DPH1_k127_4582555_12	700598.Niako_4480	4.095e-08	65.0	COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DPH1_k127_4582555_0	679926.Mpet_1819	8.883e-132	440.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,2N969@224756|Methanomicrobia	224756|Methanomicrobia	N	PFAM type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DPH1_k127_4582555_6	589924.Ferp_1432	1.254e-27	129.0	COG2064@1|root,arCOG01808@2157|Archaea,2XTM3@28890|Euryarchaeota,2463Q@183980|Archaeoglobi	183980|Archaeoglobi	N	PFAM type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DPH1_k127_477562_2	1379698.RBG1_1C00001G1267	1.17e-90	324.0	COG0419@1|root,COG0419@2|Bacteria,2NPX7@2323|unclassified Bacteria	2|Bacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C
DPH1_k127_477562_3	1379698.RBG1_1C00001G1268	1.123e-81	285.0	COG0420@1|root,COG0420@2|Bacteria,2NQ16@2323|unclassified Bacteria	2|Bacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
DPH1_k127_477562_4	1343739.PAP_07680	1.197e-78	280.0	COG0446@1|root,arCOG01069@2157|Archaea,2XT0A@28890|Euryarchaeota,24368@183968|Thermococci	183968|Thermococci	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.6.3.3	ko:K17870	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
DPH1_k127_477562_14	1380390.JIAT01000011_gene2627	6.991e-06	61.0	COG4733@1|root,COG4733@2|Bacteria,2HNSD@201174|Actinobacteria,4CSA3@84995|Rubrobacteria	84995|Rubrobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_477562_8	436308.Nmar_0456	1.444e-27	133.0	COG5276@1|root,arCOG02565@2157|Archaea	2157|Archaea	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DPH1_k127_477562_12	497964.CfE428DRAFT_3274	1.674e-08	70.0	COG0737@1|root,COG2374@1|root,COG4733@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,COG4733@2|Bacteria,46VVX@74201|Verrucomicrobia	74201|Verrucomicrobia	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
DPH1_k127_477562_13	635013.TherJR_1425	1.348e-06	64.0	COG3005@1|root,COG4733@1|root,COG3005@2|Bacteria,COG4733@2|Bacteria,1UT1Y@1239|Firmicutes,250WR@186801|Clostridia,265BU@186807|Peptococcaceae	186801|Clostridia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DPH1_k127_477562_6	1054217.TALC_01274	7.438e-47	179.0	COG1890@1|root,arCOG04186@2157|Archaea,2XSX9@28890|Euryarchaeota,241QV@183967|Thermoplasmata	183967|Thermoplasmata	J	structural constituent of ribosome	rps3ae	-	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
DPH1_k127_477562_5	351160.RRC439	3.073e-63	226.0	COG1533@1|root,arCOG01290@2157|Archaea,2XY2A@28890|Euryarchaeota,2N9Z2@224756|Methanomicrobia	224756|Methanomicrobia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DPH1_k127_477562_0	351160.RRC440	6.295e-147	477.0	COG1602@1|root,arCOG04269@2157|Archaea,2XTEQ@28890|Euryarchaeota,2NADJ@224756|Methanomicrobia	224756|Methanomicrobia	S	Pfam:DUF650	-	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
DPH1_k127_477562_11	673860.AciM339_1080	6.024e-18	89.0	COG1658@1|root,arCOG01486@2157|Archaea,2Y18J@28890|Euryarchaeota,3F2UV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	TOPRIM	-	-	-	-	-	-	-	-	-	-	-	-	Toprim
DPH1_k127_477562_9	679926.Mpet_1306	6.486e-21	95.0	COG1872@1|root,arCOG04058@2157|Archaea,2XZV9@28890|Euryarchaeota,2N9YJ@224756|Methanomicrobia	224756|Methanomicrobia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DPH1_k127_477562_10	1042877.GQS_08160	1.312e-20	95.0	COG1308@1|root,arCOG04061@2157|Archaea,2XXYV@28890|Euryarchaeota,244FN@183968|Thermococci	183968|Thermococci	J	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
DPH1_k127_477562_1	1236689.MMALV_03080	3.645e-110	373.0	COG0063@1|root,arCOG00018@2157|Archaea,2XU4W@28890|Euryarchaeota,3F2MH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DPH1_k127_477562_7	351160.LRC424	1.438e-39	153.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,2N9DU@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM metallophosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DPH1_k127_4909429_2	1347392.CCEZ01000007_gene2017	4.026e-101	351.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,36E7X@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DPH1_k127_4909429_3	477974.Daud_1672	3.876e-98	355.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia,2639I@186807|Peptococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
DPH1_k127_4909429_10	742727.HMPREF9447_04383	2.542e-19	103.0	2DKMJ@1|root,309XW@2|Bacteria,4NNRT@976|Bacteroidetes,2FQNM@200643|Bacteroidia,4ANYS@815|Bacteroidaceae	976|Bacteroidetes	S	Peptidase C10 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I69,Peptidase_C10
DPH1_k127_4909429_6	1041930.Mtc_0921	1.662e-54	209.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,2N9P9@224756|Methanomicrobia	224756|Methanomicrobia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DPH1_k127_4909429_9	1254432.SCE1572_38450	3.014e-31	128.0	COG0454@1|root,COG0456@2|Bacteria,1RJ1K@1224|Proteobacteria,4319U@68525|delta/epsilon subdivisions,2WWI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DPH1_k127_4909429_8	351160.RCIX327	2.092e-37	163.0	arCOG02945@1|root,arCOG02945@2157|Archaea,2Y7CN@28890|Euryarchaeota,2N9XD@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4909429_11	351160.RCIX328	1.595e-16	93.0	arCOG05167@1|root,arCOG05167@2157|Archaea,2Y1Q8@28890|Euryarchaeota,2NA5S@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4909429_13	1041930.Mtc_m1	2.656e-07	58.0	arCOG05166@1|root,arCOG05166@2157|Archaea,2Y1JS@28890|Euryarchaeota,2NA51@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4909429_5	762982.HMPREF9442_03088	6.553e-64	248.0	COG1520@1|root,COG4870@1|root,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
DPH1_k127_4909429_12	215358.XP_010732163.1	4.109e-10	72.0	KOG2563@1|root,KOG2563@2759|Eukaryota,38GTZ@33154|Opisthokonta,3BA29@33208|Metazoa,3CYWF@33213|Bilateria,47ZY1@7711|Chordata,48ZEW@7742|Vertebrata	33208|Metazoa	S	heme transporter activity	FLVCR2	GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0020037,GO:0022857,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:1901363,GO:1901678	-	ko:K08220	-	-	-	-	ko00000,ko02000	2.A.1.28.1,2.A.1.28.4	-	-	MFS_1
DPH1_k127_4909429_0	868131.MSWAN_1228	1.715e-143	467.0	COG1541@1|root,arCOG02620@2157|Archaea,2XU3A@28890|Euryarchaeota	28890|Euryarchaeota	H	coenzyme F390 synthetase	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DPH1_k127_4909429_1	690850.Desaf_0604	1.561e-102	353.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,42N9T@68525|delta/epsilon subdivisions,2WIMI@28221|Deltaproteobacteria,2M7S9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DPH1_k127_4909429_4	1379698.RBG1_1C00001G0675	5.576e-93	318.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
DPH1_k127_4909429_7	439481.Aboo_1247	1.19e-37	149.0	COG1590@1|root,arCOG04156@2157|Archaea,2XWQD@28890|Euryarchaeota,3F3BG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72	taw3	-	2.1.1.282	ko:K15450	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TYW3
DPH1_k127_5002794_2	1297581.H919_06701	8.118e-128	417.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,4HB2M@91061|Bacilli	91061|Bacilli	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DPH1_k127_5002794_17	411901.BACCAC_02223	6.38e-28	118.0	COG0735@1|root,COG0735@2|Bacteria,4NSR4@976|Bacteroidetes,2FSFY@200643|Bacteroidia,4AQJV@815|Bacteroidaceae	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DPH1_k127_5002794_4	767817.Desgi_3401	6.027e-89	302.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,266U0@186807|Peptococcaceae	186801|Clostridia	C	Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
DPH1_k127_5002794_11	706587.Desti_1245	1.958e-53	192.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MRP3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
DPH1_k127_5002794_14	439481.Aboo_0874	4.474e-38	148.0	COG1633@1|root,arCOG01103@2157|Archaea,2Y69T@28890|Euryarchaeota,3F3G4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DPH1_k127_5002794_7	909663.KI867150_gene2365	9.228e-83	278.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2MQTD@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Ferritin-like domain	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DPH1_k127_5002794_15	521011.Mpal_1670	1.251e-32	128.0	COG0425@1|root,arCOG02062@2157|Archaea	2157|Archaea	O	redox protein regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
DPH1_k127_5002794_13	1047013.AQSP01000144_gene917	3.402e-46	169.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
DPH1_k127_5002794_0	521011.Mpal_1672	3.075e-159	511.0	COG1104@1|root,arCOG00066@2157|Archaea,2Y7J8@28890|Euryarchaeota,2N92C@224756|Methanomicrobia	28890|Euryarchaeota	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DPH1_k127_5002794_9	368407.Memar_2146	5.952e-64	221.0	COG0822@1|root,arCOG02077@2157|Archaea,2XX32@28890|Euryarchaeota,2N9TW@224756|Methanomicrobia	224756|Methanomicrobia	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DPH1_k127_5002794_10	744872.Spica_1836	3.291e-54	192.0	COG2033@1|root,COG2033@2|Bacteria,2J8F0@203691|Spirochaetes	203691|Spirochaetes	C	Desulfoferrodoxin ferrous iron-binding domain	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
DPH1_k127_5002794_18	521011.Mpal_2587	3.733e-19	91.0	COG3388@1|root,arCOG01345@2157|Archaea,2XXVY@28890|Euryarchaeota,2N9YC@224756|Methanomicrobia	224756|Methanomicrobia	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5002794_21	1047013.AQSP01000122_gene2224	5.086e-11	74.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
DPH1_k127_5002794_1	439481.Aboo_1300	5.596e-141	460.0	COG1363@1|root,arCOG01518@2157|Archaea,2XW74@28890|Euryarchaeota,3F2FY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Aminopeptidase I zinc metalloprotease (M18)	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
DPH1_k127_5002794_6	234267.Acid_5783	7.759e-86	304.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DPH1_k127_5002794_20	1184251.TCELL_0685	1.574e-13	75.0	arCOG07453@1|root,arCOG07453@2157|Archaea,2XRIG@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
DPH1_k127_5002794_16	1121335.Clst_2336	3.184e-28	130.0	COG1541@1|root,COG1541@2|Bacteria,1V5FH@1239|Firmicutes,24DHW@186801|Clostridia	186801|Clostridia	H	coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
DPH1_k127_5002794_8	880072.Desac_1648	3.3e-70	252.0	COG3919@1|root,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,42U1R@68525|delta/epsilon subdivisions,2X2JR@28221|Deltaproteobacteria,2MS8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5002794_12	439235.Dalk_1637	6.726e-53	198.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42UM2@68525|delta/epsilon subdivisions,2WR61@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DPH1_k127_5002794_5	264732.Moth_0831	1.269e-88	308.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,42IC3@68295|Thermoanaerobacterales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DPH1_k127_5002794_23	156978.CIMIT_03750	1.81e-07	64.0	2DBID@1|root,2Z9FF@2|Bacteria,2I5A2@201174|Actinobacteria,22KS7@1653|Corynebacteriaceae	201174|Actinobacteria	S	Uncharacterised protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5002794_3	368407.Memar_2311	9.697e-106	359.0	COG1541@1|root,arCOG02624@2157|Archaea,2XY74@28890|Euryarchaeota,2NAJN@224756|Methanomicrobia	224756|Methanomicrobia	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
DPH1_k127_5002794_22	96561.Dole_2014	1.351e-09	71.0	COG1974@1|root,COG3291@1|root,COG4870@1|root,COG1974@2|Bacteria,COG3291@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.2.1.4,3.4.21.88	ko:K01179,ko:K01356,ko:K13735,ko:K21449	ko00500,ko01100,ko05100,map00500,map01100,map05100	M00729	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03400	1.B.40.2	GH5,GH9	-	CHU_C,DUF11,Peptidase_C1,Peptidase_S24
DPH1_k127_5016074_1	1236689.MMALV_15400	1.047e-30	124.0	COG0030@1|root,arCOG04131@2157|Archaea,2XU1Q@28890|Euryarchaeota,3F2MQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DPH1_k127_5016074_0	1094980.Mpsy_1449	1.401e-206	666.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,2N9AX@224756|Methanomicrobia	224756|Methanomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C
DPH1_k127_5365071_12	374847.Kcr_0638	5.926e-64	235.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DPH1_k127_5365071_26	339860.Msp_0198	5.968e-31	123.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,23PPK@183925|Methanobacteria	183925|Methanobacteria	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
DPH1_k127_5365071_8	1123371.ATXH01000006_gene875	4.611e-97	333.0	COG0351@1|root,COG1992@1|root,COG0351@2|Bacteria,COG1992@2|Bacteria,2GHD1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Phosphomethylpyrimidine kinase	-	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
DPH1_k127_5365071_1	673860.AciM339_0762	4.273e-194	624.0	COG4231@1|root,arCOG01609@2157|Archaea,2XUNR@28890|Euryarchaeota,3F2HQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,Fer4_7,POR_N,TPP_enzyme_C
DPH1_k127_5365071_18	1054217.TALC_00961	4.482e-46	174.0	COG1014@1|root,arCOG01602@2157|Archaea,2XXK2@28890|Euryarchaeota,242GA@183967|Thermoplasmata	183967|Thermoplasmata	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
DPH1_k127_5365071_0	439481.Aboo_0912	4.155e-269	849.0	COG0046@1|root,arCOG00641@2157|Archaea,2XU49@28890|Euryarchaeota,3F2HX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0536	AIRS,AIRS_C
DPH1_k127_5365071_36	644281.MFS40622_0064	4.362e-20	93.0	COG1828@1|root,arCOG04462@2157|Archaea,2XYPB@28890|Euryarchaeota,23R76@183939|Methanococci	183939|Methanococci	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DPH1_k127_5365071_21	387631.Asulf_01084	5.436e-39	151.0	COG0237@1|root,arCOG01045@2157|Archaea,2XWNJ@28890|Euryarchaeota,245NW@183980|Archaeoglobi	183980|Archaeoglobi	H	Belongs to the UPF0200 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17,RNA_binding
DPH1_k127_5365071_11	386456.JQKN01000014_gene3127	3.592e-65	231.0	COG3503@1|root,arCOG04370@2157|Archaea,2XWYK@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
DPH1_k127_5365071_14	180332.JTGN01000002_gene5590	2.934e-59	216.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
DPH1_k127_5365071_6	693661.Arcve_1000	5.698e-115	380.0	COG0150@1|root,arCOG00639@2157|Archaea,2XTBA@28890|Euryarchaeota,245YB@183980|Archaeoglobi	183980|Archaeoglobi	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DPH1_k127_5365071_46	661478.OP10G_3156	4.026e-06	59.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DPH1_k127_5365071_13	192952.MM_1365	7.221e-61	222.0	COG0611@1|root,arCOG00638@2157|Archaea,2XSUK@28890|Euryarchaeota,2N9G5@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DPH1_k127_5365071_52	551789.ATVJ01000001_gene1876	0.0003421	53.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RM62@1224|Proteobacteria,2UPDY@28211|Alphaproteobacteria,440IE@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PPC
DPH1_k127_5365071_7	272844.PAB1859	1.685e-111	372.0	COG1180@1|root,arCOG00946@2157|Archaea,2XUB7@28890|Euryarchaeota,242R9@183968|Thermococci	183968|Thermococci	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DPH1_k127_5365071_10	1054217.TALC_00556	3.814e-75	264.0	COG1537@1|root,arCOG01741@2157|Archaea,2XTQ4@28890|Euryarchaeota,241SZ@183967|Thermoplasmata	183967|Thermoplasmata	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_3
DPH1_k127_5365071_5	342949.PNA2_0051	1.037e-116	400.0	COG1293@1|root,arCOG01695@2157|Archaea,2XTMF@28890|Euryarchaeota,243BD@183968|Thermococci	183968|Thermococci	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
DPH1_k127_5365071_33	880073.Calab_0529	2.467e-21	108.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	iAF987.Gmet_0348	Cofac_haem_bdg,PA,PDZ_2,Peptidase_M1,Peptidase_M28,Trypsin_2
DPH1_k127_5365071_41	1105031.HMPREF1141_3431	1.142e-10	74.0	COG4927@1|root,COG4927@2|Bacteria,1VU66@1239|Firmicutes,25DM7@186801|Clostridia	186801|Clostridia	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
DPH1_k127_5365071_31	323259.Mhun_0953	5.179e-22	100.0	COG0745@1|root,arCOG02595@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K07668,ko:K07669	ko02020,map02020	M00459,M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DPH1_k127_5365071_16	304371.MCP_0807	2.771e-48	184.0	COG2202@1|root,arCOG02329@1|root,arCOG02329@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_5365071_30	1056512.D515_01263	1.994e-27	120.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,1RPYK@1236|Gammaproteobacteria,1XVAR@135623|Vibrionales	135623|Vibrionales	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
DPH1_k127_5365071_32	1191523.MROS_0653	1.067e-21	109.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
DPH1_k127_5365071_50	694429.Pyrfu_0779	3.595e-05	57.0	arCOG02487@1|root,arCOG03876@1|root,arCOG07760@1|root,arCOG02487@2157|Archaea,arCOG03876@2157|Archaea,arCOG07760@2157|Archaea	2157|Archaea	M	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DPH1_k127_5365071_9	1379698.RBG1_1C00001G1092	2.489e-92	334.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
DPH1_k127_5365071_38	1121101.HMPREF1532_01912	8.723e-16	91.0	COG4870@1|root,COG4870@2|Bacteria,4PNXD@976|Bacteroidetes,2G101@200643|Bacteroidia	976|Bacteroidetes	O	Propeptide_C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,Propeptide_C25
DPH1_k127_5365071_22	926560.KE387023_gene3745	2.621e-38	164.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.15	ko:K01365,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00537,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I42,Peptidase_C1
DPH1_k127_5365071_24	1347392.CCEZ01000043_gene498	2.966e-34	137.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,36FEP@31979|Clostridiaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DPH1_k127_5365071_2	1041930.Mtc_0743	2.829e-187	601.0	COG1031@1|root,arCOG01359@2157|Archaea,2XSVQ@28890|Euryarchaeota,2N9B0@224756|Methanomicrobia	224756|Methanomicrobia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DPH1_k127_5365071_49	1232683.ADIMK_1154	3.593e-05	53.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,1T01F@1236|Gammaproteobacteria,467UT@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_5365071_44	795359.TOPB45_1316	6.327e-09	59.0	COG1522@1|root,COG1522@2|Bacteria,2GI4U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_5365071_3	1031288.AXAA01000033_gene1339	6.417e-127	418.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,36E9B@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
DPH1_k127_5365071_35	439481.Aboo_0779	1.994e-20	106.0	COG4870@1|root,arCOG02501@1|root,arCOG03439@1|root,arCOG02501@2157|Archaea,arCOG03439@2157|Archaea,arCOG03607@2157|Archaea	2157|Archaea	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,Big_3_5,NosD,PKD,Peptidase_C1,S_layer_C
DPH1_k127_5365071_48	944479.JQLX01000011_gene856	2.018e-05	57.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,42NVZ@68525|delta/epsilon subdivisions,2WV1U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_5365071_34	673860.AciM339_0292	8.592e-21	108.0	COG4870@1|root,arCOG02501@1|root,arCOG03439@1|root,arCOG02501@2157|Archaea,arCOG03439@2157|Archaea,arCOG03614@2157|Archaea,2XZI4@28890|Euryarchaeota	28890|Euryarchaeota	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_5365071_28	439481.Aboo_0341	1.141e-28	121.0	COG1656@1|root,arCOG04290@2157|Archaea,2XXTT@28890|Euryarchaeota,3F3CD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
DPH1_k127_5365071_29	1151117.AJLF01000001_gene1702	1.434e-27	114.0	COG2412@1|root,arCOG04051@2157|Archaea,2XYQK@28890|Euryarchaeota,244B2@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
DPH1_k127_5365071_42	871963.Desdi_1227	3.36e-10	72.0	COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,249UT@186801|Clostridia,267BB@186807|Peptococcaceae	186801|Clostridia	G	PFAM Sugar (and other) transporter	-	-	-	ko:K08368,ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
DPH1_k127_5365071_53	443143.GM18_2166	0.0009112	51.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,42M7B@68525|delta/epsilon subdivisions,2WJUM@28221|Deltaproteobacteria,43T9V@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DPH1_k127_5365071_20	886293.Sinac_6848	3.307e-43	172.0	COG0451@1|root,COG0451@2|Bacteria,2J2KW@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DPH1_k127_5365071_23	1449126.JQKL01000003_gene1810	2.431e-35	150.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
DPH1_k127_5365071_45	653045.Strvi_4575	8.524e-09	67.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569,Transglut_core
DPH1_k127_5365071_27	439235.Dalk_1155	6.055e-31	138.0	COG1541@1|root,COG1541@2|Bacteria,1QA97@1224|Proteobacteria,43E7Y@68525|delta/epsilon subdivisions,2X5A4@28221|Deltaproteobacteria,2MPD8@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
DPH1_k127_5365071_4	386456.JQKN01000002_gene2774	6.742e-125	413.0	COG1415@1|root,arCOG04253@2157|Archaea,2XU0W@28890|Euryarchaeota,23PHY@183925|Methanobacteria	183925|Methanobacteria	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
DPH1_k127_5365071_40	765420.OSCT_1100	9.865e-11	73.0	COG0392@1|root,COG0392@2|Bacteria,2GADT@200795|Chloroflexi,375NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DPH1_k127_5365071_17	459349.CLOAM0313	1.035e-46	194.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,DUF3857,GBS_Bsp-like,Transglut_core
DPH1_k127_5365071_51	269799.Gmet_0751	0.0001893	55.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
DPH1_k127_5365071_25	1123288.SOV_3c04560	2.086e-33	138.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H408@909932|Negativicutes	909932|Negativicutes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DPH1_k127_5365071_15	1123288.SOV_3c04560	7.987e-57	207.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H408@909932|Negativicutes	909932|Negativicutes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DPH1_k127_5365071_19	1054217.TALC_01127	5.088e-45	168.0	COG0717@1|root,arCOG04048@2157|Archaea,2Y6CE@28890|Euryarchaeota,241VF@183967|Thermoplasmata	183967|Thermoplasmata	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
DPH1_k127_5365071_37	637905.SVI_1922	6.586e-16	92.0	COG3291@1|root,COG5640@1|root,COG3291@2|Bacteria,COG5640@2|Bacteria,1PDUK@1224|Proteobacteria,1S8QS@1236|Gammaproteobacteria,2Q8NA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,Peptidase_M43
DPH1_k127_5365071_43	215803.DB30_1296	1.201e-09	72.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DPH1_k127_5365071_39	1033806.HTIA_2513	2.511e-13	83.0	arCOG02420@1|root,arCOG03991@1|root,arCOG02420@2157|Archaea,arCOG03991@2157|Archaea,2Y822@28890|Euryarchaeota	28890|Euryarchaeota	S	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Pilin_N
DPH1_k127_5365071_47	123214.PERMA_0937	1.12e-05	53.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_5403874_6	386456.JQKN01000022_gene65	2.179e-17	94.0	arCOG02499@1|root,arCOG02545@1|root,arCOG02552@1|root,arCOG02499@2157|Archaea,arCOG02545@2157|Archaea,arCOG02552@2157|Archaea	2157|Archaea	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,NosD,PKD
DPH1_k127_5403874_8	1492737.FEM08_08170	0.0002547	45.0	28HGP@1|root,2Z7SG@2|Bacteria,4NI2F@976|Bacteroidetes,1HY68@117743|Flavobacteriia,2NYIA@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5403874_4	589924.Ferp_2240	5.85e-24	106.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2466S@183980|Archaeoglobi	183980|Archaeoglobi	O	PFAM Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DPH1_k127_5403874_2	1121406.JAEX01000045_gene2755	1.115e-46	190.0	2A79N@1|root,30W69@2|Bacteria,1PHGN@1224|Proteobacteria,42ZJ6@68525|delta/epsilon subdivisions,2WUWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_5403874_0	1123242.JH636435_gene1524	1.636e-120	408.0	COG2936@1|root,COG2936@2|Bacteria,2J2G5@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DPH1_k127_5403874_5	351160.RCIX1696	2.403e-18	102.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5403874_3	459349.CLOAM0442	4.276e-32	147.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
DPH1_k127_5403874_7	945713.IALB_1719	1.304e-12	83.0	COG1404@1|root,COG4409@1|root,COG1404@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,CelD_N,FlgD_ig,Glyco_hydro_9,VCBS
DPH1_k127_5403874_1	1121403.AUCV01000008_gene1542	2.878e-50	195.0	COG4870@1|root,COG4870@2|Bacteria,1RJ0M@1224|Proteobacteria,42V4Z@68525|delta/epsilon subdivisions,2WRZX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_56313_17	386456.JQKN01000022_gene65	1.288e-53	212.0	arCOG02499@1|root,arCOG02545@1|root,arCOG02552@1|root,arCOG02499@2157|Archaea,arCOG02545@2157|Archaea,arCOG02552@2157|Archaea	2157|Archaea	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,NosD,PKD
DPH1_k127_56313_11	273075.Ta0351	1.91e-79	280.0	COG0183@1|root,arCOG01280@2157|Archaea,2Y85P@28890|Euryarchaeota,241YR@183967|Thermoplasmata	183967|Thermoplasmata	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DPH1_k127_56313_27	443143.GM18_2087	3.432e-16	87.0	COG1545@1|root,COG1545@2|Bacteria,1NPAR@1224|Proteobacteria,42WW8@68525|delta/epsilon subdivisions,2WSYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DPH1_k127_56313_37	1173026.Glo7428_2698	0.0007876	47.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_56313_19	1379281.AVAG01000013_gene1465	1.251e-46	174.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2MGMG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM metal-dependent phosphohydrolase HD sub	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
DPH1_k127_56313_22	439481.Aboo_1279	7.299e-31	124.0	COG0361@1|root,arCOG01179@2157|Archaea,2XXX0@28890|Euryarchaeota,3F2RM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	eif1a	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
DPH1_k127_56313_16	351160.LRC287	4.319e-56	205.0	COG1718@1|root,arCOG01180@2157|Archaea,2XU2H@28890|Euryarchaeota,2N9ET@224756|Methanomicrobia	224756|Methanomicrobia	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
DPH1_k127_56313_18	439481.Aboo_1281	1.344e-49	182.0	COG1094@1|root,arCOG04150@2157|Archaea,2XUHX@28890|Euryarchaeota,3F2NS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	K homology RNA-binding domain	dim2	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
DPH1_k127_56313_32	671065.MetMK1DRAFT_00030980	2.471e-07	63.0	COG1241@1|root,arCOG00439@2157|Archaea,2XQ2Z@28889|Crenarchaeota	28889|Crenarchaeota	L	Belongs to the MCM family	-	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Intein_splicing,MCM,MCM_N,MCM_OB
DPH1_k127_56313_15	673860.AciM339_1503	1.004e-61	222.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,3F2P1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
DPH1_k127_56313_36	215803.DB30_3947	0.0003844	54.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,430Q8@68525|delta/epsilon subdivisions,2WVYQ@28221|Deltaproteobacteria,2YU06@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
DPH1_k127_56313_30	661478.OP10G_2205	5.612e-08	66.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179,ko:K13276	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Cellulase,F5_F8_type_C,FIVAR
DPH1_k127_56313_20	485918.Cpin_2593	1.203e-32	147.0	COG1470@1|root,COG1470@2|Bacteria,4P0GS@976|Bacteroidetes	976|Bacteroidetes	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_56313_4	795359.TOPB45_1045	2.413e-110	364.0	COG0152@1|root,COG0152@2|Bacteria,2GH07@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DPH1_k127_56313_0	673860.AciM339_0956	2.899e-244	774.0	COG0143@1|root,arCOG00810@2157|Archaea,2XTG5@28890|Euryarchaeota,3F2F7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A0543	Anticodon_1,tRNA-synt_1g,tRNA_bind
DPH1_k127_56313_2	565033.GACE_2088	4.694e-125	413.0	COG0358@1|root,arCOG04281@2157|Archaea,2XTHB@28890|Euryarchaeota,245WB@183980|Archaeoglobi	183980|Archaeoglobi	L	DNA primase	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
DPH1_k127_56313_31	573063.Metin_0780	9.216e-08	58.0	COG1745@1|root,arCOG02254@2157|Archaea,2XZ09@28890|Euryarchaeota,23R3I@183939|Methanococci	183939|Methanococci	S	Uncharacterised protein family UPF0058	-	-	-	-	-	-	-	-	-	-	-	-	UPF0058
DPH1_k127_56313_23	673860.AciM339_1247	4.183e-30	124.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,3F2UC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
DPH1_k127_56313_8	386456.JQKN01000002_gene2868	6.574e-90	303.0	COG1635@1|root,arCOG00574@2157|Archaea,2XTXH@28890|Euryarchaeota,23PFD@183925|Methanobacteria	183925|Methanobacteria	H	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	-	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	Thi4
DPH1_k127_56313_28	1041930.Mtc_0389	1.411e-15	82.0	arCOG02981@1|root,arCOG02981@2157|Archaea,2Y76A@28890|Euryarchaeota,2NBDG@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_56313_1	673860.AciM339_0619	9.296e-136	439.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,3F2HE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Intein_splicing,Rad51
DPH1_k127_56313_9	1121889.AUDM01000013_gene1874	3.421e-89	312.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,2NV0G@237|Flavobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DPH1_k127_56313_21	439481.Aboo_0714	2.623e-32	136.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y69G@28890|Euryarchaeota,3F39I@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_56313_34	439481.Aboo_0715	1.842e-05	54.0	arCOG02452@1|root,arCOG02452@2157|Archaea,2Y71S@28890|Euryarchaeota,3F36K@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	COG0467 RecA-superfamily ATPases implicated in signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_56313_13	673860.AciM339_0349	5.433e-69	242.0	COG0467@1|root,arCOG01171@2157|Archaea,2XTU3@28890|Euryarchaeota,3F31P@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Rad51	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_56313_7	351160.LRC481	2.06e-91	310.0	COG0037@1|root,arCOG00042@2157|Archaea,2XTEZ@28890|Euryarchaeota,2N92N@224756|Methanomicrobia	224756|Methanomicrobia	D	PFAM PP-loop domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
DPH1_k127_56313_14	673860.AciM339_1521	9.491e-66	231.0	COG0179@1|root,arCOG00235@2157|Archaea,2XU30@28890|Euryarchaeota,3F35H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DPH1_k127_56313_33	984262.SGRA_3014	7.113e-06	59.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1IW9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DPH1_k127_56313_26	304371.MCP_2098	6.615e-17	83.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota,2NA39@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_56313_10	326427.Cagg_3180	2.744e-80	281.0	COG0366@1|root,COG0366@2|Bacteria,2G7J7@200795|Chloroflexi,377YN@32061|Chloroflexia	32061|Chloroflexia	G	Alpha-amylase domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
DPH1_k127_56313_29	96561.Dole_1896	5.587e-13	76.0	COG0346@1|root,COG0346@2|Bacteria,1P708@1224|Proteobacteria,432H7@68525|delta/epsilon subdivisions,2WXRS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_56313_24	673860.AciM339_0553	1.744e-22	99.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_56313_12	1121889.AUDM01000013_gene1874	2.487e-77	277.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,2NV0G@237|Flavobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DPH1_k127_56313_25	374847.Kcr_0385	4.846e-19	99.0	COG1470@1|root,arCOG03511@1|root,arCOG07813@1|root,arCOG02087@2157|Archaea,arCOG03511@2157|Archaea,arCOG07813@2157|Archaea	2157|Archaea	C	LamG domain protein jellyroll fold domain protein	-	-	2.4.99.18,3.5.1.56	ko:K03418,ko:K07151	ko00510,ko00513,ko00630,ko01100,ko04141,map00510,map00513,map00630,map01100,map04141	M00072	R02509,R04216,R05976	RC00005,RC00111,RC00482,RC00731	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,DUF2341,Laminin_G_3,PKD,Pilin_N,STT3
DPH1_k127_56313_3	1343739.PAP_05040	5.725e-119	407.0	COG1297@1|root,arCOG04807@2157|Archaea,2XVCD@28890|Euryarchaeota,243GY@183968|Thermococci	183968|Thermococci	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DPH1_k127_56313_5	1121422.AUMW01000019_gene1806	7.541e-108	358.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DPH1_k127_56313_6	1121423.JONT01000003_gene979	1.934e-100	334.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DPH1_k127_5701353_1	1183377.Py04_1540	2.568e-30	123.0	COG0164@1|root,arCOG04121@2157|Archaea,2XWYC@28890|Euryarchaeota,242VW@183968|Thermococci	183968|Thermococci	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DPH1_k127_5701353_0	1122919.KB905559_gene1380	3.217e-109	361.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,26SI9@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
DPH1_k127_5757598_22	644281.MFS40622_1254	6.526e-23	102.0	COG3373@1|root,arCOG03422@2157|Archaea,2XZ1J@28890|Euryarchaeota,23RV0@183939|Methanococci	183939|Methanococci	K	Winged helix DNA-binding domain (DUF1495)	-	-	-	ko:K09745	-	-	-	-	ko00000	-	-	-	DUF1495
DPH1_k127_5757598_0	1094980.Mpsy_1916	2.439e-153	491.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,2N9G6@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
DPH1_k127_5757598_16	195522.BD01_0275	1.911e-57	207.0	COG1756@1|root,arCOG04122@2157|Archaea,2XX9G@28890|Euryarchaeota,243H9@183968|Thermococci	183968|Thermococci	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
DPH1_k127_5757598_8	673860.AciM339_0890	3.54e-98	329.0	COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,3F2GM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DPH1_k127_5757598_5	673860.AciM339_0552	9.401e-106	357.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,3F2GZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
DPH1_k127_5757598_3	459349.CLOAM1219	8.925e-144	484.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DPH1_k127_5757598_4	459349.CLOAM0769	4.589e-115	391.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DPH1_k127_5757598_28	391612.CY0110_14960	2.245e-08	57.0	COG2105@1|root,COG2105@2|Bacteria,1GMJI@1117|Cyanobacteria,3KKGV@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4314
DPH1_k127_5757598_18	426368.MmarC7_0950	2.556e-39	157.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23QBM@183939|Methanococci	183939|Methanococci	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_5757598_10	1121335.Clst_1990	6.592e-92	314.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1VRTV@1239|Firmicutes,24H21@186801|Clostridia	186801|Clostridia	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DPH1_k127_5757598_29	1094980.Mpsy_1554	6.109e-08	65.0	arCOG02527@1|root,arCOG02527@2157|Archaea,2Y6XK@28890|Euryarchaeota,2NAMP@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5757598_26	673860.AciM339_0553	1.295e-15	78.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_5757598_20	1183377.Py04_1768	8.767e-28	115.0	COG1581@1|root,arCOG01753@2157|Archaea,2Y0UY@28890|Euryarchaeota,245IQ@183968|Thermococci	183968|Thermococci	J	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
DPH1_k127_5757598_1	1054217.TALC_00031	1.832e-150	480.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,241JU@183967|Thermoplasmata	183967|Thermoplasmata	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfbA	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DPH1_k127_5757598_11	673860.AciM339_1025	3.622e-69	239.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,3F2KX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbp	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DPH1_k127_5757598_21	589924.Ferp_1102	3.067e-26	111.0	COG4738@1|root,arCOG04377@2157|Archaea,2XYIC@28890|Euryarchaeota,246AV@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5757598_23	304371.MCP_2098	1.773e-17	82.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota,2NA39@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5757598_19	509191.AEDB02000099_gene3933	7.642e-31	124.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3WJCH@541000|Ruminococcaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
DPH1_k127_5757598_25	269797.Mbar_A2569	2.837e-16	89.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
DPH1_k127_5757598_17	1121434.AULY01000011_gene1705	2.147e-52	193.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,42U9T@68525|delta/epsilon subdivisions,2WQPQ@28221|Deltaproteobacteria,2MCJT@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
DPH1_k127_5757598_24	192952.MM_1686	4.269e-17	93.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota	28890|Euryarchaeota	C	reductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
DPH1_k127_5757598_15	1379281.AVAG01000090_gene309	6.72e-58	211.0	COG0398@1|root,COG0398@2|Bacteria,1Q62Z@1224|Proteobacteria,43ECR@68525|delta/epsilon subdivisions,2X24U@28221|Deltaproteobacteria,2M7XB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DPH1_k127_5757598_9	1322246.BN4_10887	1.862e-92	313.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,42QKH@68525|delta/epsilon subdivisions,2WMW7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
DPH1_k127_5757598_13	1121413.JMKT01000016_gene49	4.141e-62	221.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,42RU9@68525|delta/epsilon subdivisions,2WNP7@28221|Deltaproteobacteria,2MBGV@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DPH1_k127_5757598_2	945713.IALB_2155	3.073e-145	476.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iPC815.YPO3230,iSBO_1134.SBO_0243	M20_dimer,Peptidase_M20
DPH1_k127_5757598_7	1459636.NTE_02180	1.569e-102	339.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
DPH1_k127_5757598_14	386456.JQKN01000015_gene2945	1.269e-60	214.0	COG1704@1|root,arCOG04574@2157|Archaea,2XXB9@28890|Euryarchaeota,23PHV@183925|Methanobacteria	183925|Methanobacteria	S	PFAM LemA	-	-	-	-	-	-	-	-	-	-	-	-	LemA
DPH1_k127_5757598_12	1395513.P343_05505	2.081e-64	232.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,26PCX@186821|Sporolactobacillaceae	91061|Bacilli	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
DPH1_k127_5757598_27	445971.ANASTE_01964	1.785e-10	68.0	COG0716@1|root,COG0716@2|Bacteria,1V4P0@1239|Firmicutes,24INM@186801|Clostridia,25XDW@186806|Eubacteriaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
DPH1_k127_5757598_6	439481.Aboo_0507	1.3e-105	360.0	COG0470@1|root,arCOG00470@2157|Archaea,2XT81@28890|Euryarchaeota,3F2FB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcL	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,Rad17
DPH1_k127_5933549_23	456442.Mboo_0718	7.532e-19	91.0	COG3385@1|root,arCOG03902@2157|Archaea,2XVZ6@28890|Euryarchaeota,2NBES@224756|Methanomicrobia	224756|Methanomicrobia	L	Transposase IS4 family protein	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1
DPH1_k127_5933549_1	439481.Aboo_1131	8.62e-221	697.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,3F2FS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TCP-1/cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
DPH1_k127_5933549_22	439481.Aboo_1347	6.129e-19	95.0	COG0576@1|root,arCOG04772@2157|Archaea,2Y6XV@28890|Euryarchaeota,3F2TX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DPH1_k127_5933549_0	304371.MCP_2019	1.697e-241	760.0	COG0443@1|root,arCOG03060@2157|Archaea,2XT86@28890|Euryarchaeota,2N91T@224756|Methanomicrobia	224756|Methanomicrobia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DPH1_k127_5933549_25	1341679.P253_01052	5.867e-15	80.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,1SFMR@1236|Gammaproteobacteria,3NNC8@468|Moraxellaceae	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DPH1_k127_5933549_21	243232.MJ_0653	2.983e-19	93.0	COG0517@1|root,arCOG00606@2157|Archaea,2XX11@28890|Euryarchaeota,23QUR@183939|Methanococci	183939|Methanococci	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_5933549_19	1304865.JAGF01000001_gene344	6.301e-22	105.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_5933549_29	439235.Dalk_1384	7.547e-07	59.0	COG4870@1|root,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria	1224|Proteobacteria	O	PFAM Peptidase C1A, papain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_5933549_24	634497.HAH_1576	1.154e-15	83.0	arCOG04617@1|root,arCOG04617@2157|Archaea,2XWGV@28890|Euryarchaeota,23V9E@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5933549_3	673860.AciM339_1081	5.879e-157	506.0	COG0180@1|root,arCOG01887@2157|Archaea,2XSVC@28890|Euryarchaeota,3F2N6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1374	tRNA-synt_1b
DPH1_k127_5933549_7	673860.AciM339_0566	1.127e-126	412.0	COG0731@1|root,arCOG04174@2157|Archaea,2XSTF@28890|Euryarchaeota,3F2ET@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
DPH1_k127_5933549_18	673860.AciM339_0306	4.994e-26	111.0	COG2450@1|root,arCOG02263@2157|Archaea,2XXYF@28890|Euryarchaeota,3F3BW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Pfam:DUF552	sepF	-	-	ko:K09152	-	-	-	-	ko00000	-	-	-	SepF
DPH1_k127_5933549_16	443254.Marpi_0645	6.673e-42	177.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CHU_C,HATPase_c,HTH_18,Kelch_1,PQQ_2,PQQ_3,Peptidase_C25,Propeptide_C25,Reg_prop,Response_reg,VCBS,Y_Y_Y
DPH1_k127_5933549_26	28072.Nos7524_1286	5.044e-14	86.0	COG2931@1|root,COG3210@1|root,COG3291@1|root,COG3595@1|root,COG4070@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3595@2|Bacteria,COG4070@2|Bacteria,1GHDQ@1117|Cyanobacteria,1HUA0@1161|Nostocales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
DPH1_k127_5933549_30	339670.Bamb_0512	1.304e-06	58.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria,1K0H2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0227)	yqiA	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
DPH1_k127_5933549_17	523845.AQXV01000040_gene1688	2.448e-34	137.0	COG2016@1|root,arCOG00985@2157|Archaea,2XX1R@28890|Euryarchaeota,23QZV@183939|Methanococci	183939|Methanococci	J	PFAM PUA domain containing protein	-	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K07575	-	-	-	-	ko00000	-	-	-	DUF1947,PUA
DPH1_k127_5933549_20	439481.Aboo_1391	2.062e-19	89.0	COG1958@1|root,arCOG00998@2157|Archaea,2XZTF@28890|Euryarchaeota,3F2SB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	snRNP Sm proteins	lsm	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
DPH1_k127_5933549_27	224325.AF_0874	5.159e-13	70.0	COG2126@1|root,arCOG04126@2157|Archaea,2XZUV@28890|Euryarchaeota,246G1@183980|Archaeoglobi	183980|Archaeoglobi	J	Binds to the 23S rRNA	rpl37e	-	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
DPH1_k127_5933549_6	351160.LRC381	7.012e-127	413.0	COG4608@1|root,arCOG00184@2157|Archaea,2Y5BH@28890|Euryarchaeota,2N9H8@224756|Methanomicrobia	224756|Methanomicrobia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iAF692.Mbar_A0472	ABC_tran,oligo_HPY
DPH1_k127_5933549_10	857293.CAAU_0438	3.365e-115	381.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DPH1_k127_5933549_14	351160.LRC379	1.915e-101	340.0	COG1173@1|root,arCOG00748@2157|Archaea,2XUIX@28890|Euryarchaeota,2N9GM@224756|Methanomicrobia	224756|Methanomicrobia	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DPH1_k127_5933549_12	351160.LRC378	2.931e-111	368.0	COG0601@1|root,arCOG00751@2157|Archaea,2XTRU@28890|Euryarchaeota,2NAQG@224756|Methanomicrobia	224756|Methanomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DPH1_k127_5933549_5	439481.Aboo_1255	2.323e-140	468.0	COG0747@1|root,arCOG01534@2157|Archaea,2XTPJ@28890|Euryarchaeota,3F353@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DPH1_k127_5933549_9	373903.Hore_04940	9.778e-122	398.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WAI0@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
DPH1_k127_5933549_8	515635.Dtur_1163	3.558e-125	408.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
DPH1_k127_5933549_13	511051.CSE_09240	6.915e-102	339.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DPH1_k127_5933549_11	511051.CSE_09230	9.179e-115	378.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	dppB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	iECUMN_1333.ECUMN_4053	BPD_transp_1
DPH1_k127_5933549_2	511051.CSE_09220	7.865e-190	607.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DPH1_k127_5933549_4	1459636.NTE_00007	1.708e-140	473.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
DPH1_k127_5933549_31	1459636.NTE_00004	0.0001565	52.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
DPH1_k127_5933549_15	1184251.TCELL_0929	2.287e-66	233.0	COG1801@1|root,arCOG04291@2157|Archaea,2XPQ4@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
DPH1_k127_5933549_28	351160.RCIX1696	1.64e-10	72.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5999164_29	660470.Theba_0222	2.7e-17	94.0	COG1470@1|root,COG3291@1|root,COG1470@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM,NPCBM_assoc,PEGA
DPH1_k127_5999164_19	459349.CLOAM0582	1.051e-43	175.0	COG1572@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	F5_F8_type_C,Glucosaminidase,SLH
DPH1_k127_5999164_32	1246995.AFR_15625	6.155e-15	87.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,2GNGF@201174|Actinobacteria,4DCKI@85008|Micromonosporales	201174|Actinobacteria	G	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
DPH1_k127_5999164_49	521011.Mpal_0104	0.0009021	50.0	arCOG02911@1|root,arCOG02911@2157|Archaea	2157|Archaea	M	toxin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5999164_24	436308.Nmar_0456	7.504e-28	133.0	COG5276@1|root,arCOG02565@2157|Archaea	2157|Archaea	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DPH1_k127_5999164_23	436308.Nmar_0456	4.018e-30	140.0	COG5276@1|root,arCOG02565@2157|Archaea	2157|Archaea	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DPH1_k127_5999164_40	679926.Mpet_0741	1.609e-07	66.0	COG1520@1|root,COG3291@1|root,arCOG02416@1|root,arCOG07813@1|root,arCOG02416@2157|Archaea,arCOG02482@2157|Archaea,arCOG02508@2157|Archaea,arCOG07813@2157|Archaea,2XUI1@28890|Euryarchaeota	28890|Euryarchaeota	T	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_5999164_28	436308.Nmar_0456	3.278e-18	100.0	COG5276@1|root,arCOG02565@2157|Archaea	2157|Archaea	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DPH1_k127_5999164_48	1380390.JIAT01000014_gene6288	3.047e-05	57.0	COG0028@1|root,COG0515@1|root,COG1470@1|root,COG2133@1|root,COG3291@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1470@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
DPH1_k127_5999164_14	387631.Asulf_00246	7.505e-49	187.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DPH1_k127_5999164_17	673860.AciM339_0007	2.714e-45	175.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,3F36C@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DPH1_k127_5999164_4	1094980.Mpsy_0841	2.8e-161	526.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,2N969@224756|Methanomicrobia	224756|Methanomicrobia	N	PFAM type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DPH1_k127_5999164_6	368407.Memar_2003	3.288e-151	505.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,2N969@224756|Methanomicrobia	224756|Methanomicrobia	N	PFAM type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DPH1_k127_5999164_3	439481.Aboo_0152	2.392e-189	601.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,3F32N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	cobW
DPH1_k127_5999164_8	523850.TON_1414	2.748e-122	400.0	COG0470@1|root,arCOG00469@2157|Archaea,2XTC8@28890|Euryarchaeota,2433R@183968|Thermococci	183968|Thermococci	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcS	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,DNA_pol3_delta2,HTH_3,Intein_splicing,LAGLIDADG_3,Rep_fac_C,RuvB_N
DPH1_k127_5999164_43	1117319.PSPO_18416	3.276e-06	55.0	COG1522@1|root,COG1522@2|Bacteria,1RH53@1224|Proteobacteria,1S493@1236|Gammaproteobacteria,2Q29D@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_5999164_7	1343739.PAP_02650	8.478e-127	419.0	COG0403@1|root,arCOG00077@2157|Archaea,2XT39@28890|Euryarchaeota,242SE@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
DPH1_k127_5999164_2	342949.PNA2_0820	2.677e-198	629.0	COG1003@1|root,arCOG00076@2157|Archaea,2XT3V@28890|Euryarchaeota,242MV@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
DPH1_k127_5999164_47	693661.Arcve_1047	2.735e-05	50.0	COG1369@1|root,arCOG01365@2157|Archaea,2Y7CZ@28890|Euryarchaeota,246I3@183980|Archaeoglobi	183980|Archaeoglobi	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp2	-	3.1.26.5	ko:K03537	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	RNase_P_Rpp14
DPH1_k127_5999164_11	1236689.MMALV_01790	4.674e-71	249.0	COG0592@1|root,arCOG00488@2157|Archaea,2XT8B@28890|Euryarchaeota,3F2MA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
DPH1_k127_5999164_38	1041930.Mtc_0389	4.146e-09	64.0	arCOG02981@1|root,arCOG02981@2157|Archaea,2Y76A@28890|Euryarchaeota,2NBDG@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5999164_10	1379698.RBG1_1C00001G1092	4.791e-82	301.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
DPH1_k127_5999164_46	368407.Memar_2016	1.36e-05	50.0	arCOG07824@1|root,arCOG07824@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SAP
DPH1_k127_5999164_44	412597.AEPN01000019_gene1059	3.435e-06	55.0	COG1522@1|root,COG1522@2|Bacteria,1RCWU@1224|Proteobacteria,2U7ME@28211|Alphaproteobacteria,2PWAH@265|Paracoccus	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_5999164_41	272559.BF9343_2262	2.308e-07	58.0	2E998@1|root,333HI@2|Bacteria,4NX30@976|Bacteroidetes,2FUKA@200643|Bacteroidia,4ASS1@815|Bacteroidaceae	976|Bacteroidetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
DPH1_k127_5999164_45	314230.DSM3645_21362	5.08e-06	54.0	2BRMF@1|root,32KKV@2|Bacteria,2J49V@203682|Planctomycetes	203682|Planctomycetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
DPH1_k127_5999164_18	439481.Aboo_0961	5.443e-45	169.0	COG0663@1|root,arCOG01849@2157|Archaea,2XXXX@28890|Euryarchaeota,3F38H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
DPH1_k127_5999164_36	443254.Marpi_1309	6.455e-11	65.0	COG1278@1|root,COG1278@2|Bacteria,2GDFN@200918|Thermotogae	200918|Thermotogae	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DPH1_k127_5999164_33	156978.CIMIT_03750	1.926e-13	83.0	2DBID@1|root,2Z9FF@2|Bacteria,2I5A2@201174|Actinobacteria,22KS7@1653|Corynebacteriaceae	201174|Actinobacteria	S	Uncharacterised protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5999164_42	879243.Poras_0107	2.145e-06	55.0	arCOG05093@1|root,339N6@2|Bacteria,4NYIM@976|Bacteroidetes,2FVF5@200643|Bacteroidia,22YYW@171551|Porphyromonadaceae	976|Bacteroidetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
DPH1_k127_5999164_39	997829.HMPREF1121_00554	6.922e-08	59.0	arCOG05093@1|root,339N6@2|Bacteria,4NYIM@976|Bacteroidetes,2FVF5@200643|Bacteroidia,22YYW@171551|Porphyromonadaceae	976|Bacteroidetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
DPH1_k127_5999164_21	1121017.AUFG01000003_gene3459	1.146e-37	149.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4FGMY@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
DPH1_k127_5999164_31	1459636.NTE_00644	2.582e-15	82.0	arCOG07179@1|root,arCOG07179@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5999164_26	419665.Maeo_0213	2.723e-26	111.0	COG1594@1|root,arCOG00579@2157|Archaea,2XY3E@28890|Euryarchaeota,23R2W@183939|Methanococci	183939|Methanococci	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	RNA_POL_M_15KD,TFIIS_C
DPH1_k127_5999164_15	439481.Aboo_1086	1.377e-46	172.0	COG1051@1|root,COG2005@1|root,arCOG00223@2157|Archaea,arCOG01075@2157|Archaea,2XXS4@28890|Euryarchaeota,3F39U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DPH1_k127_5999164_30	639282.DEFDS_1024	5.238e-16	85.0	COG1763@1|root,COG1763@2|Bacteria,2GFTP@200930|Deferribacteres	200930|Deferribacteres	H	Molybdopterin guanine dinucleotide synthesis protein B	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
DPH1_k127_5999164_35	1227349.C170_16050	6.451e-11	74.0	COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4HA7C@91061|Bacilli,26RFF@186822|Paenibacillaceae	91061|Bacilli	P	fosmidomycin resistance protein	fsr	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
DPH1_k127_5999164_12	485914.Hmuk_3110	1.598e-52	197.0	COG0697@1|root,arCOG00271@2157|Archaea,2XT64@28890|Euryarchaeota,23TZT@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_5999164_34	523850.TON_0296	5.52e-12	74.0	COG0614@1|root,COG2041@1|root,arCOG00266@2157|Archaea,arCOG04233@2157|Archaea,2XWVN@28890|Euryarchaeota,243BK@183968|Thermococci	183968|Thermococci	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
DPH1_k127_5999164_27	351160.LRC332	2.092e-25	115.0	arCOG01190@1|root,arCOG01190@2157|Archaea	351160.LRC332|-	G	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5999164_22	459349.CLOAM0708	2.621e-34	137.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K00196	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	-	Fer4,Fer4_4,Fer4_6
DPH1_k127_5999164_1	1449126.JQKL01000023_gene202	1.21e-276	870.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,26A1J@186813|unclassified Clostridiales	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
DPH1_k127_5999164_25	1122947.FR7_0395	2.241e-26	116.0	COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,4H4MC@909932|Negativicutes	909932|Negativicutes	S	GPR1 FUN34 yaaH family protein	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
DPH1_k127_5999164_20	1379698.RBG1_1C00001G1092	3.054e-41	166.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
DPH1_k127_5999164_5	673860.AciM339_0590	9.257e-159	511.0	COG0269@1|root,arCOG00053@2157|Archaea,2XV47@28890|Euryarchaeota,3F2IP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Aldolase/RraA	-	-	4.1.2.43,5.3.1.27	ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
DPH1_k127_5999164_13	717231.Flexsi_0011	5.756e-51	193.0	COG2768@1|root,COG2768@2|Bacteria,2GEZ9@200930|Deferribacteres	200930|Deferribacteres	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
DPH1_k127_5999164_16	694431.DESACE_07605	7.755e-46	168.0	COG1671@1|root,COG1671@2|Bacteria,1P0CU@1224|Proteobacteria,431PK@68525|delta/epsilon subdivisions,2WX4Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5999164_9	1168034.FH5T_20550	5.92e-108	365.0	COG2223@1|root,COG2223@2|Bacteria,4NHX9@976|Bacteroidetes,2FZ04@200643|Bacteroidia	976|Bacteroidetes	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
DPH1_k127_5999164_0	673860.AciM339_1507	5.48e-295	931.0	COG0423@1|root,COG0525@1|root,arCOG00405@2157|Archaea,arCOG00808@2157|Archaea,2XSXQ@28890|Euryarchaeota,3F2GU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Anticodon-binding domain of tRNA	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1976	Anticodon_1,tRNA-synt_1
DPH1_k127_6002643_120	1329516.JPST01000048_gene1919	0.000181	55.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,27BMG@186824|Thermoactinomycetaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-TG,RHS_repeat
DPH1_k127_6002643_94	443906.CMM_0825	1.046e-18	100.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_6002643_2	858215.Thexy_0923	1.805e-214	710.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,42EJU@68295|Thermoanaerobacterales	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DPH1_k127_6002643_105	273063.STK_04890	1.045e-12	74.0	COG1522@1|root,arCOG01580@2157|Archaea,2XQS8@28889|Crenarchaeota	28889|Crenarchaeota	K	ASNC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_6002643_103	1250006.JHZZ01000001_gene2893	2.711e-14	78.0	COG1522@1|root,COG1522@2|Bacteria,4NHG9@976|Bacteroidetes,1HXEQ@117743|Flavobacteriia,3VVF3@52959|Polaribacter	976|Bacteroidetes	K	helix_turn_helix ASNC type	asnC	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_6002643_116	323850.Shew_0638	3.126e-07	64.0	COG4547@1|root,COG4547@2|Bacteria,1NPP2@1224|Proteobacteria,1SMSB@1236|Gammaproteobacteria,2QAD2@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Cobalamin biosynthesis protein CobT VWA domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
DPH1_k127_6002643_106	378806.STAUR_1665	1.114e-11	78.0	COG1409@1|root,COG2356@1|root,COG3420@1|root,COG1409@2|Bacteria,COG2356@2|Bacteria,COG3420@2|Bacteria,1QDC2@1224|Proteobacteria,43E26@68525|delta/epsilon subdivisions,2WZH1@28221|Deltaproteobacteria,2Z24T@29|Myxococcales	28221|Deltaproteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_101	1333523.L593_10660	6.801e-16	92.0	COG3291@1|root,COG3325@1|root,arCOG02546@2157|Archaea,arCOG07840@2157|Archaea,2Y7YU@28890|Euryarchaeota,241E0@183963|Halobacteria	183963|Halobacteria	G	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PKD
DPH1_k127_6002643_78	313596.RB2501_13489	3.978e-33	141.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
DPH1_k127_6002643_70	335543.Sfum_1732	2.444e-38	152.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WNNG@28221|Deltaproteobacteria,2MRM5@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DPH1_k127_6002643_29	351160.RRC480	1.866e-83	287.0	COG0265@1|root,arCOG02833@2157|Archaea,2XT7Y@28890|Euryarchaeota,2NAWS@224756|Methanomicrobia	28890|Euryarchaeota	O	Trypsin	degP	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DPH1_k127_6002643_33	768710.DesyoDRAFT_0376	5.865e-79	276.0	COG1143@1|root,COG2006@1|root,COG1143@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,260J6@186807|Peptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
DPH1_k127_6002643_9	552811.Dehly_0886	8.131e-144	469.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi,34DQQ@301297|Dehalococcoidia	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DPH1_k127_6002643_58	410358.Mlab_1687	9.44e-49	179.0	arCOG04820@1|root,arCOG04820@2157|Archaea,2XX4W@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
DPH1_k127_6002643_121	1208321.D104_01210	0.0005261	52.0	COG5608@1|root,COG5608@2|Bacteria,1N4VR@1224|Proteobacteria,1SAT2@1236|Gammaproteobacteria,1XMFE@135619|Oceanospirillales	135619|Oceanospirillales	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
DPH1_k127_6002643_72	1380384.JADN01000008_gene1206	1.114e-36	144.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1I1A9@117743|Flavobacteriia	976|Bacteroidetes	I	hydroxylase	-	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
DPH1_k127_6002643_14	929556.Solca_4105	7.171e-115	389.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IPCH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
DPH1_k127_6002643_63	868131.MSWAN_0618	8.651e-46	177.0	COG1575@1|root,arCOG00480@2157|Archaea,2XXM6@28890|Euryarchaeota	28890|Euryarchaeota	H	PFAM UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_6002643_86	1123009.AUID01000011_gene2232	1.644e-24	113.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DPH1_k127_6002643_52	945713.IALB_0397	6.691e-52	192.0	arCOG05416@1|root,2ZZTD@2|Bacteria	2|Bacteria	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_119	751944.HALDL1_08380	0.0001758	50.0	COG1238@1|root,arCOG03118@2157|Archaea,2XWI8@28890|Euryarchaeota,23VA4@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_115	198467.NP92_01820	2.772e-08	66.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,21WCC@150247|Anoxybacillus	91061|Bacilli	CE	Rieske [2Fe-2S] domain	yhfW	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
DPH1_k127_6002643_4	889378.Spiaf_1662	3.294e-185	590.0	COG1233@1|root,COG1233@2|Bacteria,2J5I9@203691|Spirochaetes	203691|Spirochaetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37	ko:K10027,ko:K20611	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DPH1_k127_6002643_21	1220534.B655_1671	5.419e-102	340.0	COG1562@1|root,arCOG02936@2157|Archaea,2XTG2@28890|Euryarchaeota	28890|Euryarchaeota	I	Phytoene squalene synthetase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
DPH1_k127_6002643_18	192952.MM_0813	4.112e-109	362.0	COG1683@1|root,arCOG04848@2157|Archaea,2XV91@28890|Euryarchaeota,2NANV@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
DPH1_k127_6002643_90	192952.MM_0621	4.75e-23	105.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2Y507@28890|Euryarchaeota,2NB79@224756|Methanomicrobia	224756|Methanomicrobia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
DPH1_k127_6002643_7	926561.KB900621_gene2825	8.937e-165	531.0	COG0415@1|root,COG0415@2|Bacteria,1UDZT@1239|Firmicutes,249FJ@186801|Clostridia,3WAHJ@53433|Halanaerobiales	186801|Clostridia	L	PFAM DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
DPH1_k127_6002643_93	351160.RCIX2593	2.161e-21	102.0	arCOG03622@1|root,arCOG03622@2157|Archaea,2Y55W@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_36	797302.Halru_2234	4.529e-76	266.0	arCOG06481@1|root,arCOG06481@2157|Archaea,2XV5Y@28890|Euryarchaeota,23TY8@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_83	396588.Tgr7_0574	3.617e-26	116.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,1RSC5@1236|Gammaproteobacteria,1WXN5@135613|Chromatiales	135613|Chromatiales	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3335
DPH1_k127_6002643_28	264732.Moth_0831	9.308e-84	293.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,42IC3@68295|Thermoanaerobacterales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DPH1_k127_6002643_118	443143.GM18_1659	1.15e-05	58.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_3,DUF4347,HemolysinCabind,Phosphoesterase,VCBS,fn3
DPH1_k127_6002643_104	290317.Cpha266_2036	6.352e-14	76.0	COG2522@1|root,COG2522@2|Bacteria,1FFDC@1090|Chlorobi	1090|Chlorobi	O	sequence-specific DNA binding	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	HTH_3
DPH1_k127_6002643_38	204669.Acid345_1869	1.294e-75	269.0	COG0577@1|root,COG0577@2|Bacteria,3Y36A@57723|Acidobacteria,2JIYT@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_6002643_32	717231.Flexsi_1874	1.193e-79	273.0	COG1136@1|root,COG1136@2|Bacteria,2GFQJ@200930|Deferribacteres	200930|Deferribacteres	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_6002643_87	269799.Gmet_1554	1.87e-24	108.0	COG4393@1|root,COG4393@2|Bacteria,1R507@1224|Proteobacteria,42NQA@68525|delta/epsilon subdivisions,2WQ0C@28221|Deltaproteobacteria,43UZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
DPH1_k127_6002643_48	944546.ABED_0319	2.4e-63	229.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2YMCZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Co Zn Cd efflux system component	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
DPH1_k127_6002643_66	118168.MC7420_1035	2.339e-43	179.0	COG0642@1|root,COG2202@1|root,COG3605@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_6002643_77	868131.MSWAN_2293	4.221e-34	140.0	COG2890@1|root,arCOG00109@2157|Archaea,2XWJZ@28890|Euryarchaeota,23P23@183925|Methanobacteria	183925|Methanobacteria	Q	Lysine methyltransferase	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DPH1_k127_6002643_73	1041930.Mtc_0940	2.179e-36	145.0	COG4063@1|root,arCOG03221@2157|Archaea,2XWSE@28890|Euryarchaeota,2N9GK@224756|Methanomicrobia	224756|Methanomicrobia	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrG	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA,MtrG
DPH1_k127_6002643_60	339860.Msp_0307	1.862e-47	181.0	COG1962@1|root,arCOG04336@2157|Archaea,2XV9A@28890|Euryarchaeota,23PGI@183925|Methanobacteria	183925|Methanobacteria	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA	mtrH	-	2.1.1.86	ko:K00584	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrH
DPH1_k127_6002643_53	573063.Metin_0543	1.57e-51	194.0	COG0620@1|root,arCOG01876@2157|Archaea,2XUCW@28890|Euryarchaeota,23QKE@183939|Methanococci	183939|Methanococci	E	PFAM Methionine synthase, vitamin-B12 independent	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
DPH1_k127_6002643_117	497965.Cyan7822_1036	1.355e-06	54.0	COG0207@1|root,COG0207@2|Bacteria,1G24N@1117|Cyanobacteria,3KH13@43988|Cyanothece	1117|Cyanobacteria	F	thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4346,Thymidylat_synt
DPH1_k127_6002643_85	439481.Aboo_1248	5.411e-25	115.0	COG1599@1|root,arCOG01510@2157|Archaea,2Y73X@28890|Euryarchaeota,3F3CQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	OB-fold nucleic acid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-codon
DPH1_k127_6002643_10	1123242.JH636435_gene1524	1.92e-140	466.0	COG2936@1|root,COG2936@2|Bacteria,2J2G5@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DPH1_k127_6002643_112	1123054.KB907706_gene2296	3.263e-09	70.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,Gram_pos_anchor,Laminin_G_3
DPH1_k127_6002643_22	1033806.HTIA_2062	5.758e-96	337.0	COG1549@1|root,arCOG00990@2157|Archaea,2XT9W@28890|Euryarchaeota,23SND@183963|Halobacteria	183963|Halobacteria	J	COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain	arcS	-	2.6.1.97	ko:K07557	-	-	-	-	ko00000,ko01000	-	-	-	PUA,TGT,TGT_C2
DPH1_k127_6002643_6	1121335.Clst_2027	2.894e-170	549.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3WHMW@541000|Ruminococcaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
DPH1_k127_6002643_79	1041930.Mtc_0663	5.575e-31	131.0	arCOG03142@1|root,arCOG03142@2157|Archaea,2XTSE@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_80	634498.mru_0238	1.541e-29	127.0	COG1994@1|root,arCOG00614@2157|Archaea,2XX7B@28890|Euryarchaeota,23PMM@183925|Methanobacteria	183925|Methanobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_27	224325.AF_0331	1.028e-85	297.0	COG1916@1|root,arCOG02142@2157|Archaea,2XTNE@28890|Euryarchaeota,24615@183980|Archaeoglobi	183980|Archaeoglobi	S	Pheromone shutdown protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
DPH1_k127_6002643_37	1343739.PAP_01945	1.054e-75	259.0	COG0052@1|root,arCOG04245@2157|Archaea,2XTHM@28890|Euryarchaeota,242JS@183968|Thermococci	183968|Thermococci	J	Belongs to the universal ribosomal protein uS2 family	rps2	GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DPH1_k127_6002643_99	273075.Ta1160	1.653e-16	81.0	COG1758@1|root,arCOG01268@2157|Archaea,2XZSW@28890|Euryarchaeota,241WT@183967|Thermoplasmata	183967|Thermoplasmata	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	2.7.7.6	ko:K03055	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb6
DPH1_k127_6002643_57	673860.AciM339_1119	2.908e-50	183.0	COG1841@1|root,arCOG04086@2157|Archaea,2XWGP@28890|Euryarchaeota,3F2NM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal protein L30p/L7e	rpl30	GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
DPH1_k127_6002643_25	1236689.MMALV_14060	2.065e-88	298.0	COG0098@1|root,arCOG04087@2157|Archaea,2XUQU@28890|Euryarchaeota,3F2HF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S12 plays an important role in translational accuracy	rps5	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DPH1_k127_6002643_65	439481.Aboo_1502	2.291e-44	166.0	COG0256@1|root,arCOG04088@2157|Archaea,2XTWT@28890|Euryarchaeota,3F2QM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rpl18	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18_c,Ribosomal_L5e
DPH1_k127_6002643_64	673860.AciM339_1116	1.33e-45	169.0	COG2147@1|root,arCOG04089@2157|Archaea,2XWU1@28890|Euryarchaeota,3F2Q2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl19e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
DPH1_k127_6002643_75	1236689.MMALV_14090	7.573e-36	145.0	COG1717@1|root,arCOG00781@2157|Archaea,2XSZ4@28890|Euryarchaeota,3F2PV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL32 family	rpl32e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L32e
DPH1_k127_6002643_51	644281.MFS40622_1742	9.405e-55	197.0	COG0097@1|root,arCOG04090@2157|Archaea,2XTIS@28890|Euryarchaeota,23QUY@183939|Methanococci	183939|Methanococci	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DPH1_k127_6002643_61	1094980.Mpsy_1131	1.599e-46	170.0	COG0096@1|root,arCOG04091@2157|Archaea,2XWMU@28890|Euryarchaeota,2N9Q6@224756|Methanomicrobia	224756|Methanomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DPH1_k127_6002643_96	1236689.MMALV_14120	9.392e-18	83.0	COG0199@1|root,arCOG00782@2157|Archaea,2Y68V@28890|Euryarchaeota,3F2V3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DPH1_k127_6002643_55	1054217.TALC_01321	1.257e-50	186.0	COG0094@1|root,arCOG04092@2157|Archaea,2XTRN@28890|Euryarchaeota,241QF@183967|Thermoplasmata	183967|Thermoplasmata	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DPH1_k127_6002643_43	877455.Metbo_0787	3.703e-66	233.0	COG1471@1|root,arCOG04093@2157|Archaea,2XT03@28890|Euryarchaeota,23NT9@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	-	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
DPH1_k127_6002643_88	272557.APE_0358	5.965e-24	110.0	COG0198@1|root,arCOG04094@2157|Archaea,2XQQB@28889|Crenarchaeota	28889|Crenarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,Ribosomal_L26
DPH1_k127_6002643_54	673860.AciM339_1108	8.947e-51	183.0	COG0093@1|root,arCOG04095@2157|Archaea,2XWM6@28890|Euryarchaeota,3F2NF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DPH1_k127_6002643_69	323259.Mhun_2244	9.999e-39	147.0	COG0186@1|root,arCOG04096@2157|Archaea,2XYPE@28890|Euryarchaeota,2N9XI@224756|Methanomicrobia	224756|Methanomicrobia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DPH1_k127_6002643_114	399550.Smar_1027	1.073e-08	60.0	COG1588@1|root,arCOG00784@2157|Archaea,2XR9D@28889|Crenarchaeota	28889|Crenarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	-	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
DPH1_k127_6002643_71	1236689.MMALV_14180	1.048e-37	145.0	COG0023@1|root,arCOG04223@2157|Archaea,2XXW5@28890|Euryarchaeota,3F2TV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Translation initiation factor SUI1	tif1a	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DPH1_k127_6002643_97	439481.Aboo_1514	1.518e-17	83.0	COG0255@1|root,arCOG00785@2157|Archaea,2Y1DQ@28890|Euryarchaeota,3F2VT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal L29 protein	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DPH1_k127_6002643_40	673860.AciM339_1104	3.528e-73	256.0	COG0092@1|root,arCOG04097@2157|Archaea,2XTHR@28890|Euryarchaeota,3F2JC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S3	rps3	GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DPH1_k127_6002643_76	1042877.GQS_04860	2.883e-35	139.0	COG0091@1|root,arCOG04098@2157|Archaea,2XWGN@28890|Euryarchaeota,243D0@183968|Thermococci	183968|Thermococci	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DPH1_k127_6002643_67	673860.AciM339_1102	6.485e-42	159.0	COG0185@1|root,arCOG04099@2157|Archaea,2XWI9@28890|Euryarchaeota,3F2NY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DPH1_k127_6002643_31	267377.MMP1546	8.586e-82	278.0	COG0090@1|root,arCOG04067@2157|Archaea,2XTCS@28890|Euryarchaeota,23Q5Y@183939|Methanococci	183939|Methanococci	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DPH1_k127_6002643_95	386456.JQKN01000001_gene1761	3.513e-18	86.0	COG0089@1|root,arCOG04072@2157|Archaea,2XYPG@28890|Euryarchaeota,23PSB@183925|Methanobacteria	183925|Methanobacteria	J	Ribosomal protein L23	-	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DPH1_k127_6002643_35	1236689.MMALV_14250	2.507e-76	263.0	COG0469@1|root,arCOG04071@2157|Archaea,2XTXX@28890|Euryarchaeota,3F2K6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the polypeptide exit tunnel	rpl4	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DPH1_k127_6002643_12	673860.AciM339_1098	6.313e-122	399.0	COG0087@1|root,arCOG04070@2157|Archaea,2XT9B@28890|Euryarchaeota,3F2H1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DPH1_k127_6002643_24	593750.Metfor_0423	5.46e-89	303.0	COG0226@1|root,arCOG00213@2157|Archaea,2XW2U@28890|Euryarchaeota	28890|Euryarchaeota	P	ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DPH1_k127_6002643_39	1230460.C495_04942	1.129e-73	260.0	COG0573@1|root,arCOG00167@2157|Archaea,2XVD5@28890|Euryarchaeota,23UP0@183963|Halobacteria	183963|Halobacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DPH1_k127_6002643_42	153721.MYP_601	9.184e-71	248.0	COG0581@1|root,COG0581@2|Bacteria,4NHBW@976|Bacteroidetes,47UEW@768503|Cytophagia	976|Bacteroidetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DPH1_k127_6002643_23	1499967.BAYZ01000028_gene1312	3.301e-95	318.0	COG1117@1|root,COG1117@2|Bacteria,2NP2B@2323|unclassified Bacteria	2|Bacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27,3.6.3.55	ko:K02036,ko:K02068,ko:K06857	ko02010,map02010	M00186,M00211,M00222	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.7	-	-	ABC_tran
DPH1_k127_6002643_110	593750.Metfor_0422	9.091e-10	61.0	arCOG04501@1|root,arCOG04501@2157|Archaea	2157|Archaea	S	COG2002 Regulators of stationary sporulation gene expression	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
DPH1_k127_6002643_47	573064.Mefer_1527	1.603e-63	226.0	COG1268@1|root,arCOG02986@2157|Archaea,2XWSG@28890|Euryarchaeota	28890|Euryarchaeota	S	BioY protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
DPH1_k127_6002643_19	386456.JQKN01000001_gene1834	5.164e-109	366.0	COG0124@1|root,arCOG00404@2157|Archaea,2XSYX@28890|Euryarchaeota,23NQX@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DPH1_k127_6002643_82	263820.PTO0520	1.943e-26	115.0	COG1439@1|root,arCOG00721@2157|Archaea,2XWH2@28890|Euryarchaeota,241TG@183967|Thermoplasmata	183967|Thermoplasmata	V	PIN domain of ribonuclease	-	-	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
DPH1_k127_6002643_81	1293048.CBMB010000010_gene3468	3.229e-28	125.0	COG0681@1|root,arCOG01739@2157|Archaea,2XU45@28890|Euryarchaeota,23U0G@183963|Halobacteria	183963|Halobacteria	U	COG0681 Signal peptidase I	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DPH1_k127_6002643_34	673860.AciM339_0378	1.362e-76	262.0	COG0603@1|root,arCOG00039@2157|Archaea,2XTS7@28890|Euryarchaeota,3F2JU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
DPH1_k127_6002643_8	877455.Metbo_1214	9.397e-145	468.0	COG1104@1|root,arCOG00066@2157|Archaea,2Y7J8@28890|Euryarchaeota,23NPK@183925|Methanobacteria	183925|Methanobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DPH1_k127_6002643_20	1094508.Tsac_1149	1.151e-106	355.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,42F86@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
DPH1_k127_6002643_15	1343739.PAP_07190	9.159e-112	377.0	COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,244WQ@183968|Thermococci	183968|Thermococci	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DPH1_k127_6002643_68	243231.GSU1012	5.036e-41	167.0	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
DPH1_k127_6002643_11	161156.JQKW01000007_gene838	1.107e-128	429.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GGVI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
DPH1_k127_6002643_30	224719.Abm4_1653	7.454e-82	283.0	COG1736@1|root,arCOG04112@2157|Archaea,2XSY5@28890|Euryarchaeota,23NUP@183925|Methanobacteria	183925|Methanobacteria	J	Diphthamide	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
DPH1_k127_6002643_59	1236689.MMALV_14520	2.735e-48	181.0	COG0468@1|root,arCOG00417@2157|Archaea,2XTI2@28890|Euryarchaeota,3F2NU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DNA repair and recombination protein RadB	radB	GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K04484	-	-	-	-	ko00000,ko03400	-	-	-	Rad51
DPH1_k127_6002643_107	693661.Arcve_1911	1.125e-11	73.0	COG1711@1|root,arCOG00551@2157|Archaea,2XYKZ@28890|Euryarchaeota,246AC@183980|Archaeoglobi	183980|Archaeoglobi	L	protein conserved in archaea	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	-
DPH1_k127_6002643_74	263820.PTO0407	3.391e-36	140.0	COG1631@1|root,arCOG04109@2157|Archaea,2XXV3@28890|Euryarchaeota,241RG@183967|Thermoplasmata	183967|Thermoplasmata	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
DPH1_k127_6002643_100	1094980.Mpsy_1233	1.7e-16	80.0	COG2051@1|root,arCOG04108@2157|Archaea,2XZW2@28890|Euryarchaeota,2NA0J@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM Ribosomal protein S27E	rps27e	-	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
DPH1_k127_6002643_26	673860.AciM339_1479	1.386e-86	294.0	COG1093@1|root,arCOG04107@2157|Archaea,2XTV0@28890|Euryarchaeota,3F2GS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2a	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
DPH1_k127_6002643_109	267377.MMP1706	9.091e-10	61.0	COG2260@1|root,arCOG00906@2157|Archaea,2Y1HX@28890|Euryarchaeota,23RB1@183939|Methanococci	183939|Methanococci	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
DPH1_k127_6002643_41	1041930.Mtc_1026	4.55e-73	254.0	COG2047@1|root,arCOG00348@2157|Archaea,2XSX4@28890|Euryarchaeota,2N9I4@224756|Methanomicrobia	224756|Methanomicrobia	S	PAC2 family	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
DPH1_k127_6002643_56	795359.TOPB45_0867	1.867e-50	186.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
DPH1_k127_6002643_50	1122176.KB903609_gene5261	3.637e-57	209.0	COG1030@1|root,COG1030@2|Bacteria,4PN0T@976|Bacteroidetes,1ITG9@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
DPH1_k127_6002643_46	886293.Sinac_3443	1.421e-63	221.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DPH1_k127_6002643_98	742727.HMPREF9447_04411	3.936e-17	91.0	291AZ@1|root,2ZNXZ@2|Bacteria,4NNVG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6002643_44	485913.Krac_0275	5.636e-65	232.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi	200795|Chloroflexi	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DPH1_k127_6002643_89	1424334.W822_18185	1.316e-23	114.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,3T34M@506|Alcaligenaceae	28216|Betaproteobacteria	E	Aminotransferase	aspB	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DPH1_k127_6002643_91	344747.PM8797T_04585	3.693e-22	110.0	COG4927@1|root,COG4927@2|Bacteria,2IYD9@203682|Planctomycetes	203682|Planctomycetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
DPH1_k127_6002643_17	2340.JV46_19510	1.604e-109	365.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,1RZ0G@1236|Gammaproteobacteria,1JAJY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DPH1_k127_6002643_1	673860.AciM339_0086	3.296e-219	700.0	COG0209@1|root,arCOG03713@1|root,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,3F2Z5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
DPH1_k127_6002643_92	521045.Kole_1745	8.653e-22	100.0	COG1047@1|root,COG1047@2|Bacteria,2GD8F@200918|Thermotogae	200918|Thermotogae	G	peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
DPH1_k127_6002643_5	1379698.RBG1_1C00001G0054	6.202e-182	575.0	COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria	2|Bacteria	E	Aspartate-ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA
DPH1_k127_6002643_102	882086.SacxiDRAFT_0851	1.651e-15	89.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4E1CS@85010|Pseudonocardiales	201174|Actinobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
DPH1_k127_6002643_62	459349.CLOAM0582	2.018e-46	183.0	COG1572@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	F5_F8_type_C,Glucosaminidase,SLH
DPH1_k127_6002643_13	596151.DesfrDRAFT_2511	1.509e-118	402.0	COG3118@1|root,COG3118@2|Bacteria,1QTZ9@1224|Proteobacteria,43D6I@68525|delta/epsilon subdivisions,2X8DC@28221|Deltaproteobacteria,2MHGN@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_6002643_49	429009.Adeg_2015	1.991e-60	211.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
DPH1_k127_6002643_84	1379698.RBG1_1C00001G0046	4.931e-25	109.0	COG0680@1|root,COG0680@2|Bacteria,2NS17@2323|unclassified Bacteria	2|Bacteria	C	Hydrogenase maturation protease	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
DPH1_k127_6002643_3	1449126.JQKL01000002_gene1552	4.666e-197	625.0	COG3259@1|root,COG3259@2|Bacteria,1UZNV@1239|Firmicutes,24F0H@186801|Clostridia	186801|Clostridia	C	PFAM Nickel-dependent hydrogenase, large subunit	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
DPH1_k127_6002643_16	1121422.AUMW01000038_gene3024	3.696e-110	366.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia,264VD@186807|Peptococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
DPH1_k127_6002643_45	933801.Ahos_0051	2.351e-64	233.0	COG0123@1|root,arCOG00324@2157|Archaea,2XQB3@28889|Crenarchaeota	28889|Crenarchaeota	BQ	PFAM Histone deacetylase	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
DPH1_k127_6002643_0	264732.Moth_0064	0.0	1592.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,42FWA@68295|Thermoanaerobacterales	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
DPH1_k127_6293615_26	673860.AciM339_0115	2.088e-15	76.0	COG2888@1|root,arCOG01989@2157|Archaea,2Y6XW@28890|Euryarchaeota,3F2UA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Domain of unknown function (DUF1610)	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	DUF1610
DPH1_k127_6293615_28	868131.MSWAN_1939	1.174e-13	74.0	COG2092@1|root,arCOG01988@2157|Archaea,2XYNW@28890|Euryarchaeota,23P7D@183925|Methanobacteria	183925|Methanobacteria	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
DPH1_k127_6293615_23	579137.Metvu_0421	6.668e-19	95.0	COG3398@1|root,arCOG02611@2157|Archaea,2XW64@28890|Euryarchaeota,23PZT@183939|Methanococci	183939|Methanococci	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_6293615_0	1131266.ARWQ01000001_gene1192	6.505e-143	474.0	COG0008@1|root,arCOG04302@2157|Archaea,41S5V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
DPH1_k127_6293615_9	1042877.GQS_04525	2.627e-77	271.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2435A@183968|Thermococci	183968|Thermococci	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DPH1_k127_6293615_6	273116.14324394	8.284e-88	302.0	COG1304@1|root,arCOG00613@2157|Archaea,2XT6H@28890|Euryarchaeota,241IE@183967|Thermoplasmata	183967|Thermoplasmata	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
DPH1_k127_6293615_15	1054217.TALC_01359	2.317e-56	205.0	COG1608@1|root,arCOG00860@2157|Archaea,2XSUI@28890|Euryarchaeota,241QT@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DPH1_k127_6293615_4	1305737.JAFX01000001_gene2516	4.201e-105	355.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,47NAK@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM ribosomal RNA small subunit methyltransferase RsmB	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
DPH1_k127_6293615_3	868131.MSWAN_0192	4.899e-112	368.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,23PEV@183925|Methanobacteria	183925|Methanobacteria	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DPH1_k127_6293615_1	1307761.L21SP2_0340	8.613e-121	404.0	COG2317@1|root,COG2317@2|Bacteria,2J6XW@203691|Spirochaetes	203691|Spirochaetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
DPH1_k127_6293615_12	1408473.JHXO01000007_gene819	6.579e-75	258.0	COG0588@1|root,COG0588@2|Bacteria,4NFP5@976|Bacteroidetes,2FP93@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
DPH1_k127_6293615_8	386456.JQKN01000001_gene2139	4.579e-82	285.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT1I@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DPH1_k127_6293615_10	443143.GM18_2743	7.118e-77	271.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
DPH1_k127_6293615_32	946362.XP_004990259.1	1.604e-05	59.0	2D4U4@1|root,2SWA2@2759|Eukaryota,3AVEZ@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6293615_29	1414719.CBYN010000011_gene1608	2.13e-10	74.0	2A1MP@1|root,30PVX@2|Bacteria,2HWJ3@201174|Actinobacteria,22QA6@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6293615_30	553220.CAMGR0001_2189	1.248e-07	65.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,42NVZ@68525|delta/epsilon subdivisions,2YN9J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	periplasmic copper-binding protein NosD	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_6293615_21	673860.AciM339_0553	2.923e-19	90.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_6293615_13	1047013.AQSP01000103_gene1170	1.206e-66	231.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Nitroreductase
DPH1_k127_6293615_18	439481.Aboo_0790	2.054e-47	182.0	COG1938@1|root,arCOG00347@2157|Archaea,2XT93@28890|Euryarchaeota,3F2T7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
DPH1_k127_6293615_24	546262.NEICINOT_03149	6.914e-17	89.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,2KQR7@206351|Neisseriales	206351|Neisseriales	G	Phosphoglycolate phosphatase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
DPH1_k127_6293615_20	1219084.AP014508_gene315	2.988e-42	158.0	COG0432@1|root,COG0432@2|Bacteria,2GD2P@200918|Thermotogae	200918|Thermotogae	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DPH1_k127_6293615_31	573413.Spirs_0335	6.492e-07	53.0	28ZMA@1|root,2ZMCJ@2|Bacteria,2JB7Z@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6293615_22	521011.Mpal_0501	3.408e-19	91.0	COG0695@1|root,arCOG02606@2157|Archaea,2Y0MA@28890|Euryarchaeota,2NB58@224756|Methanomicrobia	224756|Methanomicrobia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DPH1_k127_6293615_19	456442.Mboo_0831	1.157e-46	173.0	COG4802@1|root,arCOG01100@2157|Archaea,2Y8IH@28890|Euryarchaeota	28890|Euryarchaeota	C	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
DPH1_k127_6293615_5	485915.Dret_1194	4.549e-94	318.0	COG0679@1|root,COG0679@2|Bacteria,1RAR6@1224|Proteobacteria,42R7S@68525|delta/epsilon subdivisions,2WN3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
DPH1_k127_6293615_27	324925.Ppha_2388	6.69e-15	78.0	COG2522@1|root,COG2522@2|Bacteria,1FFDC@1090|Chlorobi	1090|Chlorobi	O	sequence-specific DNA binding	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	HTH_3
DPH1_k127_6293615_17	579137.Metvu_0632	1.406e-51	191.0	COG1059@1|root,arCOG04357@2157|Archaea,2XWSZ@28890|Euryarchaeota	28890|Euryarchaeota	L	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)	ogg	-	4.2.99.18	ko:K03653	-	-	-	-	ko00000,ko01000	-	-	-	-
DPH1_k127_6293615_11	1220534.B655_0710	7.174e-77	263.0	COG4912@1|root,arCOG11010@2157|Archaea,2XWKG@28890|Euryarchaeota,23PIX@183925|Methanobacteria	183925|Methanobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DPH1_k127_6293615_25	459349.CLOAM0083	1.395e-15	78.0	COG2221@1|root,COG2221@2|Bacteria	2|Bacteria	C	Nitrite and sulphite reductase 4Fe-4S	frx-2	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1033	Fer4
DPH1_k127_6293615_2	1054217.TALC_01492	1.727e-114	379.0	COG0309@1|root,arCOG00636@2157|Archaea,2XTAH@28890|Euryarchaeota,241W7@183967|Thermoplasmata	183967|Thermoplasmata	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DPH1_k127_6293615_7	420247.Msm_0340	2.013e-84	291.0	COG0492@1|root,arCOG01296@2157|Archaea,2XTJW@28890|Euryarchaeota,23PBJ@183925|Methanobacteria	183925|Methanobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DPH1_k127_6293615_14	608538.HTH_1738	2.192e-59	213.0	COG1180@1|root,COG1180@2|Bacteria,2G49Z@200783|Aquificae	200783|Aquificae	O	Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
DPH1_k127_6293615_16	1304885.AUEY01000085_gene2480	5.016e-53	189.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2MHTW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
DPH1_k127_6395215_1	269799.Gmet_2664	2.684e-99	334.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DPH1_k127_6395215_2	269799.Gmet_2664	1.198e-95	325.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DPH1_k127_6395215_8	362976.HQ_3567A	1.612e-06	51.0	arCOG06397@1|root,arCOG06397@2157|Archaea,2Y0VR@28890|Euryarchaeota,23Y2W@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6395215_5	342949.PNA2_1879	3.655e-31	131.0	arCOG05472@1|root,arCOG05472@2157|Archaea,2Y3ID@28890|Euryarchaeota,245GJ@183968|Thermococci	183968|Thermococci	S	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6395215_0	70601.3256752	7.963e-126	427.0	COG1297@1|root,arCOG04807@2157|Archaea,2XVCD@28890|Euryarchaeota,243GY@183968|Thermococci	183968|Thermococci	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DPH1_k127_6395215_4	431943.CKL_0741	1.741e-41	158.0	COG0716@1|root,COG0716@2|Bacteria,1VBEZ@1239|Firmicutes,24JJ6@186801|Clostridia,36K16@31979|Clostridiaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4,Flavodoxin_5
DPH1_k127_6395215_3	579137.Metvu_0743	2.639e-51	193.0	COG3276@1|root,arCOG01564@2157|Archaea,2XWBV@28890|Euryarchaeota,23QFU@183939|Methanococci	183939|Methanococci	J	PFAM elongation factor Tu, domain 2 protein	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
DPH1_k127_6395215_7	123214.PERMA_0937	1.089e-07	65.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_6395215_6	96561.Dole_2139	1.727e-26	127.0	COG1520@1|root,COG3325@1|root,COG4870@1|root,COG1520@2|Bacteria,COG3325@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,DUF4849,PQQ_2,PQQ_3
DPH1_k127_6448153_27	1054217.TALC_00037	1.967e-23	101.0	COG1698@1|root,arCOG04308@2157|Archaea,2XZVX@28890|Euryarchaeota,241U7@183967|Thermoplasmata	183967|Thermoplasmata	S	Uncharacterised protein family (UPF0147)	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
DPH1_k127_6448153_16	439481.Aboo_0637	5.646e-62	224.0	COG0648@1|root,arCOG01894@2157|Archaea,2XU62@28890|Euryarchaeota,3F2J1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
DPH1_k127_6448153_24	342949.PNA2_0868	5.867e-37	146.0	COG0269@1|root,arCOG00053@2157|Archaea,2Y670@28890|Euryarchaeota,242WV@183968|Thermococci	183968|Thermococci	G	SIS domain	hps	-	4.1.2.43,5.3.1.27	ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,SIS
DPH1_k127_6448153_4	439481.Aboo_0942	7.459e-210	667.0	COG0532@1|root,arCOG01560@2157|Archaea,2XU09@28890|Euryarchaeota,3F2FJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D4,IF-2,Intein_splicing,LAGLIDADG_3
DPH1_k127_6448153_0	1267535.KB906767_gene2605	0.0	1102.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria,2JJHT@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DPH1_k127_6448153_15	351160.RCIX2034	4.306e-65	229.0	COG1394@1|root,arCOG04101@2157|Archaea,2XTQ5@28890|Euryarchaeota,2N9IG@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0384	ATP-synt_D
DPH1_k127_6448153_3	589924.Ferp_2303	1.248e-226	711.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,246RN@183980|Archaeoglobi	183980|Archaeoglobi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
DPH1_k127_6448153_2	1236689.MMALV_00110	3.969e-238	749.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,3F2G5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
DPH1_k127_6448153_29	351160.RCIX2029	1.024e-19	92.0	COG1436@1|root,arCOG04102@2157|Archaea,2XXYI@28890|Euryarchaeota,2N9YY@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
DPH1_k127_6448153_14	1041930.Mtc_1398	1.49e-65	238.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,2N9HH@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0388	vATP-synt_AC39
DPH1_k127_6448153_26	192952.MM_0783	2.117e-24	109.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,2N9TB@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
DPH1_k127_6448153_32	1094980.Mpsy_2502	1.316e-13	74.0	COG0636@1|root,arCOG02455@2157|Archaea,2XZRP@28890|Euryarchaeota,2N9ZA@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM H transporting two-sector ATPase C subunit	atpK-1	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0390	ATP-synt_C
DPH1_k127_6448153_12	1041930.Mtc_1401	4.85e-83	301.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2N9EB@224756|Methanomicrobia	224756|Methanomicrobia	C	Belongs to the V-ATPase 116 kDa subunit family	atpI-1	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
DPH1_k127_6448153_31	1220534.B655_2144	3.006e-18	91.0	COG0680@1|root,arCOG04429@2157|Archaea,2XXAF@28890|Euryarchaeota,23P79@183925|Methanobacteria	183925|Methanobacteria	C	hydrogenase maturation protease HycI	hycI	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
DPH1_k127_6448153_28	696369.KI912183_gene848	7.64e-20	93.0	COG1143@1|root,COG1143@2|Bacteria,1VBXF@1239|Firmicutes,24MWM@186801|Clostridia,262DX@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
DPH1_k127_6448153_11	1033806.HTIA_2020	5.479e-98	329.0	COG1005@1|root,arCOG01546@2157|Archaea,2XT7N@28890|Euryarchaeota,23SN2@183963|Halobacteria	183963|Halobacteria	C	NADH ubiquinone oxidoreductase subunit 1 (Chain H)	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DPH1_k127_6448153_9	338966.Ppro_0595	2.171e-137	447.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,43DST@68525|delta/epsilon subdivisions,2WJ4E@28221|Deltaproteobacteria,43TGG@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH-ubiquinone oxidoreductase, chain 49kDa	-	-	1.6.5.3	ko:K00333,ko:K14090	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
DPH1_k127_6448153_30	717606.PaecuDRAFT_4076	1.04e-19	94.0	COG0852@1|root,COG0852@2|Bacteria,1UFNI@1239|Firmicutes,4HDV1@91061|Bacilli,26RPJ@186822|Paenibacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DPH1_k127_6448153_17	338966.Ppro_0593	6.214e-60	210.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WNT3@28221|Deltaproteobacteria,43UYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
DPH1_k127_6448153_10	1033806.HTIA_2023	8.528e-99	341.0	COG0651@1|root,arCOG01537@2157|Archaea,2XU88@28890|Euryarchaeota,23S0I@183963|Halobacteria	183963|Halobacteria	C	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
DPH1_k127_6448153_8	1033806.HTIA_2026	1.108e-140	467.0	COG1009@1|root,arCOG01539@2157|Archaea,2XT4R@28890|Euryarchaeota,23S49@183963|Halobacteria	183963|Halobacteria	C	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DPH1_k127_6448153_35	519442.Huta_2221	1.026e-07	58.0	arCOG15061@1|root,arCOG15061@2157|Archaea	2157|Archaea	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DPH1_k127_6448153_38	1033806.HTIA_2024	0.0001407	48.0	arCOG14849@1|root,arCOG14849@2157|Archaea	2157|Archaea	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DPH1_k127_6448153_22	572546.Arcpr_0498	7.915e-55	198.0	COG0105@1|root,arCOG04313@2157|Archaea,2XWSK@28890|Euryarchaeota,2465T@183980|Archaeoglobi	183980|Archaeoglobi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DPH1_k127_6448153_36	1226325.HMPREF1548_01508	1.949e-06	58.0	COG1266@1|root,COG1266@2|Bacteria,1VAFM@1239|Firmicutes,24DNF@186801|Clostridia,36G0R@31979|Clostridiaceae	186801|Clostridia	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DPH1_k127_6448153_19	459349.CLOAM0018	6.318e-58	229.0	COG1361@1|root,COG3420@1|root,COG1361@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_35,CBM_6,DUF11,SdrD_B
DPH1_k127_6448153_33	309799.DICTH_0269	5.95e-12	78.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	pfbA	-	-	ko:K13925	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,CW_binding_1,F5_F8_type_C,Glyco_hydro_28,Pectate_lyase_3,YSIRK_signal
DPH1_k127_6448153_39	485916.Dtox_1969	0.0003375	53.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DPH1_k127_6448153_37	1479623.JHEL01000010_gene166	0.0001245	54.0	2A1MP@1|root,30PVX@2|Bacteria,2I73S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6448153_5	370438.PTH_1770	9.638e-191	606.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,26067@186807|Peptococcaceae	186801|Clostridia	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
DPH1_k127_6448153_25	644282.Deba_1252	1.129e-34	139.0	arCOG10401@1|root,2ZA7Y@2|Bacteria,1R45R@1224|Proteobacteria,42MDG@68525|delta/epsilon subdivisions,2WKTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6448153_13	643648.Slip_0876	7.729e-67	239.0	COG2025@1|root,COG2025@2|Bacteria,1V2AY@1239|Firmicutes,24FT1@186801|Clostridia,42KA5@68298|Syntrophomonadaceae	186801|Clostridia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DPH1_k127_6448153_23	589924.Ferp_2317	1.837e-48	183.0	COG2086@1|root,arCOG00446@2157|Archaea,2XZ39@28890|Euryarchaeota	28890|Euryarchaeota	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DPH1_k127_6448153_7	1125863.JAFN01000001_gene2057	2.371e-143	472.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
DPH1_k127_6448153_6	1347392.CCEZ01000007_gene2014	2.667e-156	501.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,36DR1@31979|Clostridiaceae	186801|Clostridia	I	acyl-CoA dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_6448153_21	760568.Desku_1209	5.28e-55	197.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,261TW@186807|Peptococcaceae	186801|Clostridia	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
DPH1_k127_6448153_1	1128421.JAGA01000002_gene1135	2.186e-242	760.0	COG1884@1|root,COG1884@2|Bacteria,2NNZ9@2323|unclassified Bacteria	2|Bacteria	I	Methylmalonyl-CoA mutase	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DPH1_k127_6448153_20	370438.PTH_1362	7.249e-57	200.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
DPH1_k127_6448153_18	401526.TcarDRAFT_1687	4.801e-59	211.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,4H1WI@909932|Negativicutes	909932|Negativicutes	E	LAO AO transport system	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DPH1_k127_6560192_0	113355.CM001775_gene2547	5.144e-78	274.0	COG1131@1|root,COG1131@2|Bacteria,1G1IU@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	ccmA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DPH1_k127_6560192_1	351160.RCIX2593	5.451e-21	100.0	arCOG03622@1|root,arCOG03622@2157|Archaea,2Y55W@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6673492_10	572544.Ilyop_0969	1.31e-33	132.0	COG1979@1|root,COG1979@2|Bacteria,3792X@32066|Fusobacteria	32066|Fusobacteria	C	Iron-containing alcohol dehydrogenase	bdhA	-	-	ko:K00100	ko00650,ko01120,map00650,map01120	-	R03544,R03545	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
DPH1_k127_6673492_14	420246.GTNG_1439	3.404e-16	91.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1WE27@129337|Geobacillus	91061|Bacilli	EGP	LacY proton/sugar symporter	tetA_3	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
DPH1_k127_6673492_3	555079.Toce_1803	4.108e-116	386.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,42FCX@68295|Thermoanaerobacterales	186801|Clostridia	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
DPH1_k127_6673492_13	269797.Mbar_A1318	2.171e-18	89.0	COG3377@1|root,arCOG04424@2157|Archaea,2Y0SF@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF1805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1805
DPH1_k127_6673492_5	1321784.HMPREF1987_02271	8.977e-86	288.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DPH1_k127_6673492_12	880073.Calab_1105	3.992e-20	106.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.33.1	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS
DPH1_k127_6673492_7	1047013.AQSP01000075_gene1425	7.457e-59	211.0	COG0778@1|root,COG0778@2|Bacteria,2NPKE@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_6673492_17	1122915.AUGY01000018_gene6263	1.034e-13	84.0	COG1649@1|root,COG2755@1|root,COG4632@1|root,COG5492@1|root,COG1649@2|Bacteria,COG2755@2|Bacteria,COG4632@2|Bacteria,COG5492@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli,26QZG@186822|Paenibacillaceae	91061|Bacilli	D	Protein conserved in bacteria	yngK	-	-	-	-	-	-	-	-	-	-	-	Big_2,GHL10,SLH
DPH1_k127_6673492_11	316274.Haur_2022	1.359e-27	129.0	COG4447@1|root,COG4447@2|Bacteria,2G9IJ@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6673492_9	1054217.TALC_00198	1.44e-37	160.0	arCOG05338@1|root,arCOG05338@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6673492_15	243232.MJ_0905	2.594e-15	79.0	COG3373@1|root,arCOG03422@2157|Archaea,2XZ1J@28890|Euryarchaeota,23RV0@183939|Methanococci	183939|Methanococci	K	Winged helix DNA-binding domain (DUF1495)	-	-	-	ko:K09745	-	-	-	-	ko00000	-	-	-	DUF1495
DPH1_k127_6673492_1	1094980.Mpsy_1105	5.767e-148	492.0	arCOG01814@1|root,arCOG01814@2157|Archaea,2XT74@28890|Euryarchaeota,2N90N@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6673492_0	351160.RCIX949	1.79e-168	558.0	COG4962@1|root,arCOG01818@2157|Archaea,2XTN5@28890|Euryarchaeota,2N9AG@224756|Methanomicrobia	224756|Methanomicrobia	N	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
DPH1_k127_6673492_2	269797.Mbar_A1337	1.131e-118	394.0	COG0433@1|root,arCOG00284@2157|Archaea,2Y7NC@28890|Euryarchaeota,2NBKJ@224756|Methanomicrobia	224756|Methanomicrobia	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
DPH1_k127_6673492_18	269797.Mbar_A0276	9.404e-08	62.0	arCOG03359@1|root,arCOG03359@2157|Archaea,2Y26A@28890|Euryarchaeota,2NA5F@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6673492_16	290317.Cpha266_2036	8.112e-15	78.0	COG2522@1|root,COG2522@2|Bacteria,1FFDC@1090|Chlorobi	1090|Chlorobi	O	sequence-specific DNA binding	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	HTH_3
DPH1_k127_6673492_4	673860.AciM339_0238	1.11e-101	340.0	COG0167@1|root,arCOG00603@2157|Archaea,2XTMB@28890|Euryarchaeota,3F2FC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DPH1_k127_6673492_19	523845.AQXV01000043_gene284	0.0007	43.0	COG0543@1|root,arCOG02199@2157|Archaea,2XSY9@28890|Euryarchaeota,23QKQ@183939|Methanococci	183939|Methanococci	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DPH1_k127_6673492_8	1220534.B655_0013	2.091e-52	192.0	COG0543@1|root,arCOG02199@2157|Archaea,2XSY9@28890|Euryarchaeota,23NXK@183925|Methanobacteria	183925|Methanobacteria	C	Dihydroorotate dehydrogenase	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DPH1_k127_6673492_6	635013.TherJR_1090	2.013e-60	213.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,262HG@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_6734513_2	1123252.ATZF01000006_gene821	1.389e-165	553.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,27BHN@186824|Thermoactinomycetaceae	91061|Bacilli	P	Cation transporter/ATPase, N-terminus	yloB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	iYO844.BSU15650	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DPH1_k127_6734513_4	323259.Mhun_1465	6.696e-155	495.0	COG0205@1|root,arCOG03641@2157|Archaea	2157|Archaea	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DPH1_k127_6734513_10	439481.Aboo_1424	2.38e-89	304.0	COG1234@1|root,arCOG00501@2157|Archaea,2XTJ9@28890|Euryarchaeota,3F2KC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
DPH1_k127_6734513_40	1380390.JIAT01000014_gene6288	1.465e-07	63.0	COG0028@1|root,COG0515@1|root,COG1470@1|root,COG2133@1|root,COG3291@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1470@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
DPH1_k127_6734513_31	192952.MM_3318	7.038e-23	114.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_6734513_37	1304883.KI912532_gene2098	5.874e-09	68.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,2VIYN@28216|Betaproteobacteria,2KUTQ@206389|Rhodocyclales	206389|Rhodocyclales	P	Periplasmic copper-binding protein (NosD)	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_6734513_21	877455.Metbo_2365	1.429e-52	198.0	COG1041@1|root,arCOG00047@2157|Archaea,2XTD6@28890|Euryarchaeota,23NJD@183925|Methanobacteria	183925|Methanobacteria	L	methylase	-	-	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
DPH1_k127_6734513_14	635013.TherJR_2723	6.228e-78	273.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
DPH1_k127_6734513_22	1236689.MMALV_10880	3.197e-51	194.0	COG0402@1|root,arCOG00692@2157|Archaea,2XSYB@28890|Euryarchaeota,3F2N3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Amidohydrolase family	guaD2	-	3.5.4.1,3.5.4.3	ko:K01485,ko:K01487	ko00230,ko00240,ko00330,ko01100,map00230,map00240,map00330,map01100	-	R00974,R01411,R01676,R02922	RC00074,RC00204,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DPH1_k127_6734513_19	351160.RCIX1428	3.904e-62	224.0	COG0517@1|root,arCOG00600@2157|Archaea,2XU4J@28890|Euryarchaeota,2N994@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_6734513_0	402880.MmarC5_1458	4.056e-167	541.0	COG0423@1|root,arCOG00405@2157|Archaea,2XSZK@28890|Euryarchaeota,23QGE@183939|Methanococci	183939|Methanococci	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DPH1_k127_6734513_1	439481.Aboo_0464	9.711e-166	534.0	COG0160@1|root,arCOG00915@2157|Archaea,2XSYT@28890|Euryarchaeota,3F36Y@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.36	ko:K00823,ko:K03918	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00457,R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DPH1_k127_6734513_5	1499967.BAYZ01000013_gene6445	1.306e-154	500.0	COG1748@1|root,COG1748@2|Bacteria,2NNZ1@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lys2	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
DPH1_k127_6734513_3	1499967.BAYZ01000013_gene6446	3.479e-158	510.0	COG0686@1|root,COG0686@2|Bacteria,2NNTE@2323|unclassified Bacteria	2|Bacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	sdh	-	1.5.1.7,1.5.1.8,1.5.1.9	ko:K00290,ko:K14157	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DPH1_k127_6734513_8	552811.Dehly_1517	8.967e-139	464.0	COG1948@1|root,COG4880@2|Bacteria	2|Bacteria	L	resolution of meiotic recombination intermediates	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel,Cu_amine_oxidN1
DPH1_k127_6734513_28	765420.OSCT_1565	6.907e-30	126.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi,375P8@32061|Chloroflexia	32061|Chloroflexia	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
DPH1_k127_6734513_30	744872.Spica_0058	7.207e-25	108.0	COG1051@1|root,COG1051@2|Bacteria,2J926@203691|Spirochaetes	203691|Spirochaetes	F	TIGRFAM mutator mutT protein	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DPH1_k127_6734513_34	192952.MM_3318	4.876e-14	84.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_6734513_16	159749.K0R1M2	2.564e-74	260.0	COG1577@1|root,KOG1511@2759|Eukaryota,2XDVQ@2836|Bacillariophyta	2836|Bacillariophyta	I	GHMP kinases C terminal	-	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DPH1_k127_6734513_12	386456.JQKN01000010_gene718	4.589e-82	291.0	COG0043@1|root,arCOG01671@2157|Archaea,2XUDW@28890|Euryarchaeota,23NKJ@183925|Methanobacteria	183925|Methanobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
DPH1_k127_6734513_33	1294142.CINTURNW_2578	6.313e-15	78.0	2E481@1|root,32Z3Y@2|Bacteria,1VFF1@1239|Firmicutes,24SN5@186801|Clostridia,36NFZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6734513_11	402880.MmarC5_1670	1.809e-83	293.0	COG0585@1|root,arCOG04252@2157|Archaea,2XVPH@28890|Euryarchaeota,23Q00@183939|Methanococci	183939|Methanococci	J	tRNA pseudouridine synthase D	-	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
DPH1_k127_6734513_6	243232.MJ_1313	2.384e-146	473.0	COG1679@1|root,arCOG04278@2157|Archaea,2XTY6@28890|Euryarchaeota,23QFZ@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
DPH1_k127_6734513_26	579137.Metvu_1439	9.999e-40	151.0	COG1786@1|root,arCOG04279@2157|Archaea,2XYXJ@28890|Euryarchaeota,23R0C@183939|Methanococci	183939|Methanococci	C	Belongs to the UPF0107 family	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
DPH1_k127_6734513_38	1472418.BBJC01000004_gene1986	5.795e-08	65.0	COG5621@1|root,COG5621@2|Bacteria,1N77M@1224|Proteobacteria,2UQ5I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	secreted hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6734513_20	673860.AciM339_0827	1.393e-52	190.0	COG3481@1|root,arCOG01861@2157|Archaea,2XU10@28890|Euryarchaeota,3F2ZM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
DPH1_k127_6734513_7	439481.Aboo_0970	7.742e-142	466.0	COG0427@1|root,arCOG06124@2157|Archaea,2Y6ZI@28890|Euryarchaeota,3F308@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	PFAM Citrate lyase, alpha subunit	-	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
DPH1_k127_6734513_17	1047013.AQSP01000140_gene2448	5.344e-72	251.0	COG0372@1|root,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1,4.1.3.34	ko:K01647,ko:K15234	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R00351,R00354	RC00004,RC00067,RC00502	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DPH1_k127_6734513_9	264732.Moth_0831	1.235e-101	346.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,42IC3@68295|Thermoanaerobacterales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DPH1_k127_6734513_24	98439.AJLL01000051_gene3523	1.507e-44	175.0	COG0451@1|root,COG0451@2|Bacteria,1G48D@1117|Cyanobacteria,1JJN9@1189|Stigonemataceae	1117|Cyanobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DPH1_k127_6734513_23	266117.Rxyl_2757	1.094e-45	177.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.39,2.5.1.42	ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00117	R04520,R05000,R05615	RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_6734513_35	926692.AZYG01000064_gene942	8.951e-14	78.0	COG2518@1|root,COG2518@2|Bacteria,1UF2N@1239|Firmicutes,25NG4@186801|Clostridia,3WC2K@53433|Halanaerobiales	186801|Clostridia	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6734513_13	720554.Clocl_0489	1.546e-78	273.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3WG9U@541000|Ruminococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
DPH1_k127_6734513_39	410358.Mlab_0795	9.027e-08	63.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,2N9SR@224756|Methanomicrobia	224756|Methanomicrobia	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_6734513_36	269797.Mbar_A1696	2.455e-09	69.0	COG0535@1|root,arCOG00940@2157|Archaea	2157|Archaea	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
DPH1_k127_6734513_15	269797.Mbar_A1695	5.884e-76	268.0	COG0535@1|root,arCOG00940@2157|Archaea	2157|Archaea	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DPH1_k127_6734513_43	1121413.JMKT01000017_gene423	2.329e-05	54.0	COG2890@1|root,COG2890@2|Bacteria,1R75F@1224|Proteobacteria,42QD7@68525|delta/epsilon subdivisions,2WKXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Nicotianamine synthase protein	-	-	-	-	-	-	-	-	-	-	-	-	NAS
DPH1_k127_6734513_32	1229909.NSED_05410	2.616e-15	78.0	COG4095@1|root,arCOG05022@2157|Archaea,41SUZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv
DPH1_k127_6734513_27	1444711.CCJF01000005_gene485	1.006e-35	147.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CMAS,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
DPH1_k127_6734513_25	391623.TERMP_00265	7.78e-43	162.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWJA@28890|Euryarchaeota,243ZM@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_6734513_18	1173022.Cri9333_2199	2.529e-66	238.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1G3WZ@1117|Cyanobacteria,1HDM6@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DPH1_k127_6734513_29	335283.Neut_1097	1.234e-28	131.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VMX6@28216|Betaproteobacteria,372PI@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Capsular polysaccharide biosynthesis protein CapK	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glyco_transf_4,Glycos_transf_1
DPH1_k127_6734513_41	1047013.AQSP01000066_gene724	8.214e-07	53.0	2E5PY@1|root,330EK@2|Bacteria,2NS29@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6734513_42	273075.Ta0590a	1.485e-06	52.0	arCOG05340@1|root,arCOG05340@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6836724_2	32057.KB217478_gene3212	6.18e-20	89.0	COG2227@1|root,COG2227@2|Bacteria,1GPYP@1117|Cyanobacteria	1117|Cyanobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DPH1_k127_6836724_3	1123274.KB899407_gene259	1.405e-10	67.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
DPH1_k127_6836724_1	374847.Kcr_0638	4.732e-68	251.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DPH1_k127_6836724_0	1304872.JAGC01000005_gene2126	8.992e-93	326.0	COG3118@1|root,COG3118@2|Bacteria,1QTZ9@1224|Proteobacteria,43D80@68525|delta/epsilon subdivisions,2X8EN@28221|Deltaproteobacteria,2MHHB@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_6836724_4	1259795.ARJK01000003_gene1270	9.853e-07	51.0	COG1943@1|root,COG1943@2|Bacteria,1V608@1239|Firmicutes,25CMT@186801|Clostridia,42H1Q@68295|Thermoanaerobacterales	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DPH1_k127_6948166_10	391598.FBBAL38_09852	2.577e-125	421.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_6948166_52	457429.ABJI02000063_gene115	4.651e-12	78.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,2GNGF@201174|Actinobacteria	201174|Actinobacteria	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
DPH1_k127_6948166_28	459349.CLOAM1790	2.639e-43	174.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
DPH1_k127_6948166_12	118161.KB235922_gene3213	4.412e-110	372.0	COG0591@1|root,COG0591@2|Bacteria,1G3QJ@1117|Cyanobacteria,3VMKF@52604|Pleurocapsales	1117|Cyanobacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DPH1_k127_6948166_64	1047013.AQSP01000122_gene2224	3.548e-05	56.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
DPH1_k127_6948166_17	1408813.AYMG01000031_gene1453	1.502e-68	252.0	COG1680@1|root,COG1680@2|Bacteria,4NGXR@976|Bacteroidetes,1IR76@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DPH1_k127_6948166_51	439481.Aboo_1118	3.06e-12	72.0	COG1412@1|root,arCOG04312@2157|Archaea,2Y0D4@28890|Euryarchaeota,3F2SM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	Fcf1	-	-	-	ko:K07158	-	-	-	-	ko00000	-	-	-	PIN
DPH1_k127_6948166_4	523845.AQXV01000053_gene744	1.233e-170	545.0	COG3276@1|root,arCOG01563@2157|Archaea,2XUKU@28890|Euryarchaeota,23QPD@183939|Methanococci	183939|Methanococci	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2g	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,eIF2_C
DPH1_k127_6948166_27	439481.Aboo_0802	2.87e-45	168.0	COG2125@1|root,arCOG01946@2157|Archaea,2XXZJ@28890|Euryarchaeota,3F2RJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
DPH1_k127_6948166_41	771875.Ferpe_0089	5.903e-21	108.0	COG1520@1|root,COG1520@2|Bacteria,2GD9T@200918|Thermotogae	200918|Thermotogae	S	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6948166_63	314278.NB231_05936	2.517e-06	59.0	291NB@1|root,2ZP8I@2|Bacteria,1P5ZB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
DPH1_k127_6948166_19	589924.Ferp_2225	1.484e-59	213.0	COG1095@1|root,arCOG00675@2157|Archaea,2XT6U@28890|Euryarchaeota,2460Z@183980|Archaeoglobi	183980|Archaeoglobi	K	DNA-directed RNA polymerase	-	-	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
DPH1_k127_6948166_48	351160.RCIX624	1.765e-13	71.0	COG2093@1|root,arCOG04077@2157|Archaea,2Y0D6@28890|Euryarchaeota,2NA1J@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
DPH1_k127_6948166_34	673860.AciM339_0483	1.201e-29	124.0	COG1909@1|root,arCOG04076@2157|Archaea,2XXSG@28890|Euryarchaeota,3F2T2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
DPH1_k127_6948166_46	797209.ZOD2009_02365	4.156e-17	85.0	COG2004@1|root,arCOG04182@2157|Archaea,2XXXB@28890|Euryarchaeota,23W6E@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eukaryotic ribosomal protein eS24 family	rps24e	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S24e
DPH1_k127_6948166_44	439481.Aboo_0564	1.429e-17	83.0	COG1998@1|root,arCOG04183@2157|Archaea,2XZZ0@28890|Euryarchaeota,3F2VM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
DPH1_k127_6948166_14	304371.MCP_0994	1.859e-84	291.0	COG0598@1|root,arCOG02265@2157|Archaea,2Y2PC@28890|Euryarchaeota,2NAPG@224756|Methanomicrobia	224756|Methanomicrobia	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DPH1_k127_6948166_49	747365.Thena_0795	1.791e-13	78.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
DPH1_k127_6948166_40	694429.Pyrfu_0797	3.955e-21	103.0	COG0467@1|root,arCOG01171@2157|Archaea,2XPS8@28889|Crenarchaeota	28889|Crenarchaeota	T	Circadian clock protein KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_6948166_36	342949.PNA2_0706	1.625e-28	124.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y7MQ@28890|Euryarchaeota,243HH@183968|Thermococci	183968|Thermococci	T	KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_6948166_47	1094980.Mpsy_3158	3.026e-16	89.0	arCOG02911@1|root,arCOG02911@2157|Archaea,2Y0M6@28890|Euryarchaeota,2N9ZD@224756|Methanomicrobia	224756|Methanomicrobia	U	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6948166_39	1094980.Mpsy_0417	7.656e-23	114.0	arCOG02516@1|root,arCOG02538@1|root,arCOG03439@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,arCOG03439@2157|Archaea	2157|Archaea	L	PFAM periplasmic copper-binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CHB_HEX_C_1,PKD,PQQ_3,Peptidase_S8
DPH1_k127_6948166_53	192952.MM_1927	1.943e-11	77.0	arCOG02526@1|root,arCOG02526@2157|Archaea	2157|Archaea	O	Parallel beta-helix	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CHB_HEX_C_1,CarboxypepD_reg,DUF11,NosD,PKD
DPH1_k127_6948166_33	316067.Geob_3699	4.829e-32	128.0	COG0745@1|root,COG0745@2|Bacteria	316067.Geob_3699|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6948166_7	304371.MCP_2679	2.69e-143	473.0	COG0018@1|root,arCOG00487@2157|Archaea,2XTWP@28890|Euryarchaeota,2N9C5@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DPH1_k127_6948166_30	387631.Asulf_01737	1.17e-38	154.0	COG1533@1|root,arCOG01290@2157|Archaea,2XTYE@28890|Euryarchaeota	28890|Euryarchaeota	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DPH1_k127_6948166_37	351160.RCIX443	7.575e-26	110.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,2NAXV@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DPH1_k127_6948166_25	1313421.JHBV01000025_gene1029	6.728e-50	204.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,1IVGR@117747|Sphingobacteriia	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HATPase_c,HNOBA,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
DPH1_k127_6948166_35	693661.Arcve_1359	3.424e-29	137.0	COG3291@1|root,COG3979@1|root,arCOG02499@1|root,arCOG02552@1|root,arCOG03439@1|root,arCOG02499@2157|Archaea,arCOG02552@2157|Archaea,arCOG03439@2157|Archaea,arCOG03504@2157|Archaea,arCOG07581@2157|Archaea,2XXWR@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM periplasmic copper-binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
DPH1_k127_6948166_13	673860.AciM339_0533	3.517e-93	321.0	COG1746@1|root,arCOG04249@2157|Archaea,2XT5J@28890|Euryarchaeota,3F2HM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
DPH1_k127_6948166_42	635013.TherJR_0475	1.186e-18	96.0	COG0671@1|root,COG0671@2|Bacteria,1VBSU@1239|Firmicutes,25DCG@186801|Clostridia,263AN@186807|Peptococcaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
DPH1_k127_6948166_29	453591.Igni_0850	1.872e-42	162.0	COG1514@1|root,arCOG01736@2157|Archaea,2XQM6@28889|Crenarchaeota	28889|Crenarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DPH1_k127_6948166_18	195522.BD01_2070	1.903e-66	237.0	COG1831@1|root,arCOG00893@2157|Archaea,2XTX7@28890|Euryarchaeota,243FU@183968|Thermococci	183968|Thermococci	S	TatD related DNase	-	-	-	ko:K07049	-	-	-	-	ko00000	-	-	-	TatD_DNase
DPH1_k127_6948166_57	565033.GACE_1023	3.82e-08	66.0	COG0582@1|root,arCOG01242@2157|Archaea,2Y83U@28890|Euryarchaeota,246MT@183980|Archaeoglobi	2157|Archaea	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase,zinc_ribbon_2
DPH1_k127_6948166_8	420247.Msm_1164	4.921e-138	450.0	COG0012@1|root,arCOG00357@2157|Archaea,2XTZG@28890|Euryarchaeota,23NMZ@183925|Methanobacteria	183925|Methanobacteria	J	PFAM GTPase of	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
DPH1_k127_6948166_20	1094980.Mpsy_2322	9.677e-59	215.0	COG4801@1|root,arCOG02471@2157|Archaea,2XSX3@28890|Euryarchaeota,2N9N8@224756|Methanomicrobia	224756|Methanomicrobia	S	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,Hexapep
DPH1_k127_6948166_0	439481.Aboo_1408	6.335e-254	799.0	COG0466@1|root,arCOG02160@2157|Archaea,2XTT0@28890|Euryarchaeota,3F2HW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Belongs to the peptidase S16 family	lon	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
DPH1_k127_6948166_24	439481.Aboo_0834	1.084e-50	186.0	COG1056@1|root,arCOG00972@2157|Archaea,2XUF7@28890|Euryarchaeota,3F2N0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Cytidylyltransferase-like	nadM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DPH1_k127_6948166_65	1337936.IJ00_11705	0.0001929	53.0	COG0382@1|root,COG0382@2|Bacteria,1G2BD@1117|Cyanobacteria,1HJH8@1161|Nostocales	1117|Cyanobacteria	H	TIGRFAM bacteriochlorophyll chlorophyll synthetase	chlG	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	iJN678.chlG	UbiA
DPH1_k127_6948166_55	1407650.BAUB01000004_gene1085	9.65e-10	70.0	COG0382@1|root,COG0382@2|Bacteria,1G1UG@1117|Cyanobacteria,1H04N@1129|Synechococcus	1117|Cyanobacteria	H	Prenyltransferase, UbiA family	-	GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.5.1.115,2.5.1.116	ko:K09833	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07500,R10708	RC01840,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iJN678.slr1736	UbiA
DPH1_k127_6948166_45	604354.TSIB_1970	3.854e-17	94.0	COG1233@1|root,arCOG01521@2157|Archaea	2157|Archaea	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase,MCRA,NAD_binding_8
DPH1_k127_6948166_23	401053.AciPR4_3825	2.241e-51	197.0	COG0644@1|root,COG0644@2|Bacteria,3Y5JJ@57723|Acidobacteria,2JP4I@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DPH1_k127_6948166_56	491952.Mar181_3480	2.999e-09	68.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1XH95@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_6948166_54	456320.Mvol_1278	7.68e-11	73.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23QBM@183939|Methanococci	183939|Methanococci	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_6948166_58	472759.Nhal_2724	5.37e-08	63.0	COG2324@1|root,COG2324@2|Bacteria	2|Bacteria	S	Carotenoid biosynthesis protein	cruF	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
DPH1_k127_6948166_22	2325.TKV_c19890	4.492e-54	197.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,42FJ0@68295|Thermoanaerobacterales	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	metV	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
DPH1_k127_6948166_11	667014.Thein_2184	3.458e-111	366.0	COG0457@1|root,COG0685@1|root,COG2069@1|root,COG0457@2|Bacteria,COG0685@2|Bacteria,COG2069@2|Bacteria,2GHER@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
DPH1_k127_6948166_15	439481.Aboo_0020	1.264e-78	297.0	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,3F2U6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Patched family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DPH1_k127_6948166_50	331113.SNE_A19050	3.772e-13	77.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
DPH1_k127_6948166_60	1306947.ARQD01000004_gene163	1.331e-07	55.0	2E5PY@1|root,330EK@2|Bacteria,2NS29@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6948166_43	1094980.Mpsy_2536	2.918e-18	85.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota,2NA39@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
DPH1_k127_6948166_6	1047013.AQSP01000059_gene2098	6.31e-158	503.0	COG0451@1|root,COG0451@2|Bacteria,2NQD6@2323|unclassified Bacteria	2|Bacteria	GM	RmlD substrate binding domain	ltd	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	Epimerase
DPH1_k127_6948166_3	1048834.TC41_2255	4.624e-174	551.0	COG1830@1|root,COG1830@2|Bacteria,1TR60@1239|Firmicutes,4HT90@91061|Bacilli	91061|Bacilli	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DPH1_k127_6948166_31	391623.TERMP_00866	7.418e-38	147.0	COG2150@1|root,arCOG02316@2157|Archaea,2XWH9@28890|Euryarchaeota,242MM@183968|Thermococci	183968|Thermococci	K	regulator of amino acid metabolism	-	-	-	ko:K07103	-	-	-	-	ko00000	-	-	-	ACT
DPH1_k127_6948166_2	693661.Arcve_1364	1.558e-193	613.0	COG1350@1|root,arCOG01432@2157|Archaea,2Y845@28890|Euryarchaeota,245Q0@183980|Archaeoglobi	183980|Archaeoglobi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DPH1_k127_6948166_9	439481.Aboo_1346	6.75e-132	430.0	COG0214@1|root,arCOG04075@2157|Archaea,2XSYK@28890|Euryarchaeota,3F2HG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ,ThiG
DPH1_k127_6948166_21	673860.AciM339_0573	2.056e-56	203.0	COG0311@1|root,arCOG00034@2157|Archaea,2XTZS@28890|Euryarchaeota,3F2PW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
DPH1_k127_6948166_59	273116.14324512	1.239e-07	57.0	arCOG07411@1|root,arCOG07411@2157|Archaea,2Y1PB@28890|Euryarchaeota,242HJ@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6948166_32	673860.AciM339_0553	2.537e-32	126.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_6948166_38	289376.THEYE_A0195	2.262e-24	103.0	2E32K@1|root,32Y2U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6948166_1	1047013.AQSP01000139_gene2384	4.581e-211	674.0	COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DPH1_k127_6948166_5	1123371.ATXH01000015_gene1665	9.389e-167	541.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GHB5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
DPH1_k127_6948166_26	1054217.TALC_00153	8.308e-50	188.0	COG1339@1|root,arCOG01904@2157|Archaea,2XTFW@28890|Euryarchaeota,241PC@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)	ribK	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase,HTH_Crp_2
DPH1_k127_6948166_16	439481.Aboo_0093	2.118e-78	273.0	COG1084@1|root,arCOG00352@2157|Archaea,2XU5R@28890|Euryarchaeota,3F2J9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Nucleolar GTP-binding protein 1 (NOG1)	gbp4	-	-	ko:K06943	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	MMR_HSR1,NOG1
DPH1_k127_7123300_4	489825.LYNGBM3L_44820	1.999e-86	310.0	COG0498@1|root,COG0498@2|Bacteria,1GBSB@1117|Cyanobacteria,1HF21@1150|Oscillatoriales	1117|Cyanobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
DPH1_k127_7123300_13	665952.HMPREF1015_01423	6.52e-27	128.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,1ZCBJ@1386|Bacillus	91061|Bacilli	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15570	PAPS_reduct
DPH1_k127_7123300_9	457425.XNR_0461	5.279e-39	153.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DPH1_k127_7123300_8	439481.Aboo_0908	2.645e-59	217.0	COG1859@1|root,arCOG04063@2157|Archaea,2XWPC@28890|Euryarchaeota,3F2KG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
DPH1_k127_7123300_5	1293054.HSACCH_00610	3.703e-72	250.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,248SF@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
DPH1_k127_7123300_16	224325.AF_2371	0.0001136	52.0	arCOG01881@1|root,arCOG01881@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7123300_10	269797.Mbar_A1269	1.087e-34	153.0	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,2N99B@224756|Methanomicrobia	224756|Methanomicrobia	S	hydrophobe amphiphile efflux-3 (HAE3) family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DPH1_k127_7123300_14	647113.Metok_1106	1.053e-17	87.0	arCOG02241@1|root,arCOG02241@2157|Archaea,2XX1K@28890|Euryarchaeota,23R0E@183939|Methanococci	183939|Methanococci	K	PFAM Transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DPH1_k127_7123300_15	877455.Metbo_0585	9.444e-17	81.0	COG1849@1|root,arCOG01224@2157|Archaea,2Y279@28890|Euryarchaeota,23P92@183925|Methanobacteria	183925|Methanobacteria	S	Protein of unknown function (DUF357)	-	-	-	ko:K09728	-	-	-	-	ko00000	-	-	-	DUF357
DPH1_k127_7123300_11	416591.Tlet_0840	1.769e-34	140.0	COG1853@1|root,COG1853@2|Bacteria,2GE3B@200918|Thermotogae	200918|Thermotogae	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DPH1_k127_7123300_6	192952.MM_1017	3.698e-64	229.0	COG1912@1|root,arCOG04309@2157|Archaea,2XUEW@28890|Euryarchaeota,2N9T8@224756|Methanomicrobia	224756|Methanomicrobia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
DPH1_k127_7123300_2	243164.DET0530	5.572e-98	333.0	COG1208@1|root,COG1208@2|Bacteria,2GAPW@200795|Chloroflexi,34D0H@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DPH1_k127_7123300_0	1391646.AVSU01000034_gene2170	3.595e-182	587.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,25QFM@186804|Peptostreptococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DPH1_k127_7123300_1	589924.Ferp_2375	2.044e-130	428.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,245ZX@183980|Archaeoglobi	183980|Archaeoglobi	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DPH1_k127_7123300_12	1124780.ANNU01000021_gene2983	1.357e-28	131.0	COG2244@1|root,COG2244@2|Bacteria,4PBQX@976|Bacteroidetes,47W6P@768503|Cytophagia	976|Bacteroidetes	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7123300_7	457570.Nther_2533	1.776e-60	231.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia	1239|Firmicutes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DPH1_k127_7123300_3	1121422.AUMW01000016_gene2076	1.476e-93	312.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,26147@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,2.6.1.102	ko:K12452,ko:K13010	ko00520,map00520	-	R03391,R03392,R10460	RC00006,RC00230,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
DPH1_k127_7141209_20	323259.Mhun_0941	9.24e-05	48.0	COG3609@1|root,arCOG01009@2157|Archaea,2XZTH@28890|Euryarchaeota	28890|Euryarchaeota	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
DPH1_k127_7141209_13	269797.Mbar_A1372	2.523e-55	201.0	COG1601@1|root,arCOG01640@2157|Archaea,2XTVZ@28890|Euryarchaeota,2N9JI@224756|Methanomicrobia	224756|Methanomicrobia	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2b	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	TRAM,eIF-5_eIF-2B
DPH1_k127_7141209_7	439481.Aboo_1085	2.789e-174	561.0	COG1243@1|root,arCOG01361@2157|Archaea,2XT9Z@28890|Euryarchaeota,3F2HC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Radical_SAM C-terminal domain	elp3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
DPH1_k127_7141209_1	1054217.TALC_01538	1.284e-254	815.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,241ID@183967|Thermoplasmata	183967|Thermoplasmata	L	helicase superfamily c-terminal domain	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DPH1_k127_7141209_15	339860.Msp_0198	9.596e-25	107.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,23PPK@183925|Methanobacteria	183925|Methanobacteria	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
DPH1_k127_7141209_17	439481.Aboo_1326	7.705e-09	61.0	arCOG05352@1|root,arCOG05352@2157|Archaea,2Y75N@28890|Euryarchaeota,3F3FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7141209_14	1236689.MMALV_16490	2.842e-42	159.0	COG0640@1|root,arCOG05349@2157|Archaea,2XYUG@28890|Euryarchaeota,3F2RP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_5
DPH1_k127_7141209_9	246194.CHY_0704	3.643e-150	487.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FNV@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DPH1_k127_7141209_8	1122182.KB903833_gene5429	9.079e-169	563.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2I9U6@201174|Actinobacteria,4DH83@85008|Micromonosporales	201174|Actinobacteria	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
DPH1_k127_7141209_10	1150474.JQJI01000008_gene1355	3.958e-122	402.0	COG0498@1|root,COG0498@2|Bacteria,2GDZQ@200918|Thermotogae	200918|Thermotogae	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DPH1_k127_7141209_2	589865.DaAHT2_0126	1.652e-229	717.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2MIKK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DPH1_k127_7141209_19	243275.TDE_0035	1.65e-06	57.0	COG0454@1|root,COG0456@2|Bacteria,2J7VY@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
DPH1_k127_7141209_3	1499967.BAYZ01000081_gene1057	1.992e-200	633.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
DPH1_k127_7141209_6	945713.IALB_0300	2.126e-178	595.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
DPH1_k127_7141209_0	880073.Calab_2356	4.25e-276	884.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
DPH1_k127_7141209_12	1499967.BAYZ01000119_gene3214	1.249e-78	272.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
DPH1_k127_7141209_11	401526.TcarDRAFT_2301	2.564e-104	345.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,4H2FP@909932|Negativicutes	909932|Negativicutes	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DPH1_k127_7141209_5	246194.CHY_1991	3.314e-189	601.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
DPH1_k127_7141209_18	273057.SSO0583	1.626e-06	59.0	COG0382@1|root,arCOG00476@2157|Archaea,2XQXW@28889|Crenarchaeota	28889|Crenarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_7141209_4	342949.PNA2_0395	2.24e-191	612.0	COG0504@1|root,arCOG00063@2157|Archaea,2XTR2@28890|Euryarchaeota,2439E@183968|Thermococci	183968|Thermococci	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DPH1_k127_7141209_16	1094980.Mpsy_0913	2.672e-18	87.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,2N9DU@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM metallophosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DPH1_k127_7955661_11	192952.MM_3318	4.347e-09	70.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_7955661_6	68170.KL590490_gene1267	1.158e-40	168.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
DPH1_k127_7955661_0	1094980.Mpsy_1431	1.893e-143	467.0	COG3177@1|root,arCOG03111@2157|Archaea,2Y8I0@28890|Euryarchaeota,2NA98@224756|Methanomicrobia	224756|Methanomicrobia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_DeoR
DPH1_k127_7955661_3	456442.Mboo_2222	3.56e-48	182.0	COG0202@1|root,arCOG04241@2157|Archaea,2XTQB@28890|Euryarchaeota,2N911@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoD	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Fer4,Fer4_9,RNA_pol_A_bac,RNA_pol_L
DPH1_k127_7955661_5	1343739.PAP_01895	5.885e-46	168.0	COG0100@1|root,arCOG04240@2157|Archaea,2XX1S@28890|Euryarchaeota,243ZQ@183968|Thermococci	183968|Thermococci	J	Located on the platform of the 30S subunit	rps11	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DPH1_k127_7955661_4	439481.Aboo_1397	8.088e-48	180.0	COG0522@1|root,arCOG04239@2157|Archaea,2XXYX@28890|Euryarchaeota,3F2KM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DPH1_k127_7955661_7	1054217.TALC_00426	1.439e-40	158.0	COG0099@1|root,arCOG01722@2157|Archaea,2XWHE@28890|Euryarchaeota,241SD@183967|Thermoplasmata	183967|Thermoplasmata	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DPH1_k127_7955661_1	263820.PTO1412	3.49e-130	429.0	COG0017@1|root,arCOG00407@2157|Archaea,2XTZJ@28890|Euryarchaeota,241ZH@183967|Thermoplasmata	183967|Thermoplasmata	J	asparaginyl-tRNA aminoacylation	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DPH1_k127_7955661_8	795359.TOPB45_0303	8.836e-23	101.0	COG1254@1|root,COG1254@2|Bacteria,2GHZK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
DPH1_k127_7955661_10	1304888.ATWF01000001_gene1300	1.026e-09	72.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,ESPR,YadA_anchor,YadA_head,YadA_stalk
DPH1_k127_7955661_9	746697.Aeqsu_1953	3.856e-19	102.0	COG1520@1|root,COG1520@2|Bacteria,4NVQ3@976|Bacteroidetes	976|Bacteroidetes	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
DPH1_k127_7955661_2	761193.Runsl_5265	3.995e-68	241.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,47XPZ@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
DPH1_k127_7955661_12	536233.CLO_2304	6.592e-07	62.0	COG3291@1|root,COG3291@2|Bacteria,1TSRU@1239|Firmicutes,24BRF@186801|Clostridia,36HRJ@31979|Clostridiaceae	186801|Clostridia	S	hmm pf04151	colG	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,PPC,Peptidase_M9,Peptidase_M9_N
DPH1_k127_8049507_43	1094980.Mpsy_2426	7.521e-05	51.0	arCOG02416@1|root,arCOG02416@2157|Archaea,2Y01H@28890|Euryarchaeota,2NBNM@224756|Methanomicrobia	28890|Euryarchaeota	N	Pfam:DUF1628	pilA2	-	-	-	-	-	-	-	-	-	-	-	Pilin_N
DPH1_k127_8049507_45	662479.C440_14839	0.0009272	47.0	arCOG02416@1|root,arCOG02416@2157|Archaea,2Y01H@28890|Euryarchaeota,23XTV@183963|Halobacteria	183963|Halobacteria	N	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Pilin_N
DPH1_k127_8049507_21	272844.PAB1596	1.088e-44	175.0	COG0608@1|root,arCOG00426@2157|Archaea,2XVIX@28890|Euryarchaeota,243KC@183968|Thermococci	183968|Thermococci	L	phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8049507_29	304371.MCP_1254	5.069e-27	120.0	COG1989@1|root,arCOG02298@2157|Archaea,2XUQP@28890|Euryarchaeota,2N9XX@224756|Methanomicrobia	224756|Methanomicrobia	N	Peptidase A24A, prepilin type IV	-	-	3.4.23.52	ko:K07991	-	-	-	-	ko00000,ko01000,ko01002,ko02035,ko02044	-	-	-	Arc_PepC_II,Peptidase_A24
DPH1_k127_8049507_7	555079.Toce_0910	2.603e-115	382.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,42ESV@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DPH1_k127_8049507_28	673860.AciM339_1385	1.679e-29	124.0	COG0071@1|root,arCOG01833@2157|Archaea,2XY1D@28890|Euryarchaeota,3F2SN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Belongs to the small heat shock protein (HSP20) family	hsp20b	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DPH1_k127_8049507_8	868131.MSWAN_1950	1.858e-109	370.0	COG0595@1|root,arCOG00547@2157|Archaea,2XTIB@28890|Euryarchaeota,23PHA@183925|Methanobacteria	183925|Methanobacteria	J	PFAM RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B_2,RMMBL
DPH1_k127_8049507_15	485916.Dtox_1796	1.352e-60	223.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,261MI@186807|Peptococcaceae	186801|Clostridia	S	PFAM HD domain	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
DPH1_k127_8049507_36	323259.Mhun_2320	1.986e-15	78.0	COG2835@1|root,arCOG04124@2157|Archaea,2XZRS@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the UPF0434 family	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
DPH1_k127_8049507_0	1499967.BAYZ01000002_gene5900	0.0	1580.0	COG0458@1|root,COG0458@2|Bacteria,2NNPB@2323|unclassified Bacteria	2|Bacteria	EF	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DPH1_k127_8049507_4	1499967.BAYZ01000002_gene5899	2.534e-167	531.0	COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955,ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
DPH1_k127_8049507_6	439481.Aboo_0196	8.694e-132	445.0	COG1199@1|root,arCOG00770@2157|Archaea,2XTH2@28890|Euryarchaeota,3F2IN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	HELICc2	rad3b	-	3.6.4.12	ko:K03722,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD_2,HBB,Helicase_C_2,ResIII
DPH1_k127_8049507_14	1236689.MMALV_01840	5.015e-65	232.0	COG2520@1|root,arCOG10124@2157|Archaea,2XTPV@28890|Euryarchaeota,3F2KV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Met-10+ like-protein	taw2	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.5.1.114	ko:K07055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Met_10
DPH1_k127_8049507_19	269797.Mbar_A2412	1.102e-49	182.0	COG2042@1|root,arCOG04733@2157|Archaea,2XVBD@28890|Euryarchaeota,2N9PH@224756|Methanomicrobia	224756|Methanomicrobia	J	pre-rRNA processing protein involved in ribosome biogenesis	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
DPH1_k127_8049507_10	351160.RCIX1774	8.674e-108	366.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,2NAP4@224756|Methanomicrobia	224756|Methanomicrobia	C	CoA binding domain	acdA	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
DPH1_k127_8049507_25	694440.JOMF01000005_gene204	1.39e-34	141.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,2N9PZ@224756|Methanomicrobia	224756|Methanomicrobia	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
DPH1_k127_8049507_26	1054217.TALC_01532	2.232e-33	135.0	COG4860@1|root,arCOG04366@2157|Archaea,2XYAX@28890|Euryarchaeota,241R5@183967|Thermoplasmata	183967|Thermoplasmata	K	ArsR transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ArsR
DPH1_k127_8049507_16	386456.JQKN01000001_gene1765	1.949e-54	198.0	COG2263@1|root,arCOG00910@2157|Archaea,2XU4P@28890|Euryarchaeota,23PIV@183925|Methanobacteria	183925|Methanobacteria	Q	Ribosomal protein L11 methyltransferase (PrmA)	prmA	-	-	ko:K07579	-	-	-	-	ko00000	-	-	-	MTS,PrmA
DPH1_k127_8049507_13	1047013.AQSP01000107_gene2079	3.246e-65	226.0	COG1432@1|root,COG1432@2|Bacteria,2NRX6@2323|unclassified Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
DPH1_k127_8049507_32	573064.Mefer_0674	8.735e-23	102.0	COG0200@1|root,arCOG00779@2157|Archaea,2XWM3@28890|Euryarchaeota,23QZG@183939|Methanococci	183939|Methanococci	J	binds to the 23S rRNA	rpl15	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DPH1_k127_8049507_1	1236689.MMALV_14030	2.654e-184	590.0	COG5253@1|root,arCOG04169@2157|Archaea,2XT9A@28890|Euryarchaeota,3F2F6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
DPH1_k127_8049507_18	634498.mru_0876	6.092e-52	189.0	COG2019@1|root,arCOG01039@2157|Archaea,2XVK7@28890|Euryarchaeota,23NZH@183925|Methanobacteria	183925|Methanobacteria	F	Belongs to the archaeal adenylate kinase family	adkA	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
DPH1_k127_8049507_31	263820.PTO0665	1.837e-24	111.0	COG1422@1|root,arCOG02673@2157|Archaea,2XZDK@28890|Euryarchaeota,241UY@183967|Thermoplasmata	183967|Thermoplasmata	U	Integral membrane protein DUF106	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
DPH1_k127_8049507_20	439481.Aboo_1495	1.528e-45	170.0	COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,3F3AN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DPH1_k127_8049507_9	269797.Mbar_A0082	2.669e-108	361.0	COG0130@1|root,arCOG00987@2157|Archaea,2XTUE@28890|Euryarchaeota,2N99I@224756|Methanomicrobia	224756|Methanomicrobia	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177,ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
DPH1_k127_8049507_37	439481.Aboo_0012	8.397e-15	83.0	arCOG13491@1|root,arCOG13491@2157|Archaea,2Y6ZH@28890|Euryarchaeota,3F305@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8049507_30	673860.AciM339_1526	7.331e-27	117.0	COG3815@1|root,arCOG03949@2157|Archaea,2Y6YC@28890|Euryarchaeota,3F307@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
DPH1_k127_8049507_38	1094980.Mpsy_1328	2.491e-13	70.0	COG1552@1|root,arCOG04049@2157|Archaea,2Y177@28890|Euryarchaeota,2NB9F@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eL40 family	rpl40e	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L40e
DPH1_k127_8049507_3	1151117.AJLF01000001_gene1105	2.145e-171	550.0	COG0008@1|root,arCOG00402@2157|Archaea,2XSUM@28890|Euryarchaeota,242RZ@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DPH1_k127_8049507_17	439481.Aboo_0043	5.951e-54	199.0	COG0565@1|root,arCOG01018@2157|Archaea,2XUIY@28890|Euryarchaeota,3F2NC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	TIGRFAM RNA methyltransferase, TrmH family, group 1	trmH	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
DPH1_k127_8049507_35	673860.AciM339_0628	7.637e-17	82.0	arCOG05238@1|root,arCOG05238@2157|Archaea,2Y0YG@28890|Euryarchaeota,3F3EA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8049507_12	439481.Aboo_1446	1.619e-81	284.0	COG0750@1|root,arCOG00609@2157|Archaea,2XT29@28890|Euryarchaeota,3F2WK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
DPH1_k127_8049507_39	6500.XP_005095892.1	1.847e-06	62.0	COG5184@1|root,2QWB5@2759|Eukaryota,38G86@33154|Opisthokonta,3BBSM@33208|Metazoa,3CSQF@33213|Bilateria	33208|Metazoa	DZ	viral RNA genome replication	EEA1	GO:0003674,GO:0005488,GO:0005515,GO:0005516,GO:0005543,GO:0005545,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0005969,GO:0006810,GO:0006897,GO:0006906,GO:0006996,GO:0008150,GO:0008270,GO:0008289,GO:0009987,GO:0010008,GO:0012505,GO:0016020,GO:0016032,GO:0016043,GO:0016050,GO:0016189,GO:0016192,GO:0016197,GO:0016482,GO:0019058,GO:0019079,GO:0019897,GO:0019898,GO:0030139,GO:0030424,GO:0030742,GO:0031090,GO:0031410,GO:0031901,GO:0031982,GO:0032266,GO:0032991,GO:0033267,GO:0035091,GO:0039694,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0044308,GO:0044309,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045022,GO:0046872,GO:0046907,GO:0046914,GO:0046983,GO:0048284,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0055037,GO:0061024,GO:0061025,GO:0071840,GO:0071944,GO:0090174,GO:0097458,GO:0097708,GO:0098588,GO:0098657,GO:0098805,GO:0098927,GO:0099003,GO:0099504,GO:0099532,GO:0120025,GO:0120038,GO:1901981,GO:1902494,GO:1990234	-	ko:K12478	ko04144,ko04145,ko05152,map04144,map04145,map05152	-	-	-	ko00000,ko00001,ko04131	-	-	-	FYVE
DPH1_k127_8049507_40	419665.Maeo_0256	2.045e-06	57.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota,23Q8P@183939|Methanococci	183939|Methanococci	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB2	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_8049507_27	402880.MmarC5_1741	2.224e-30	131.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota,23QU9@183939|Methanococci	183939|Methanococci	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB1	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_8049507_42	311424.DhcVS_1412	5.11e-05	56.0	COG4191@1|root,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,34DMY@301297|Dehalococcoidia	301297|Dehalococcoidia	T	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_9,Response_reg
DPH1_k127_8049507_41	523845.AQXV01000050_gene1034	8.327e-06	57.0	COG3352@1|root,arCOG05119@2157|Archaea,2XWEH@28890|Euryarchaeota,23QS5@183939|Methanococci	183939|Methanococci	N	PFAM Flagella accessory C family protein	flaC	-	-	ko:K07822	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	FlaC_arch
DPH1_k127_8049507_33	1094980.Mpsy_2346	5.675e-22	105.0	COG3351@1|root,COG3352@1|root,arCOG02964@2157|Archaea,arCOG05119@2157|Archaea,2XVP0@28890|Euryarchaeota	28890|Euryarchaeota	N	flagella protein	flaD	-	-	ko:K07327,ko:K07328	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_fla_DE,FlaC_arch
DPH1_k127_8049507_44	797209.ZOD2009_04537	0.0001065	50.0	COG3353@1|root,arCOG01824@2157|Archaea,2XYQP@28890|Euryarchaeota,23WWZ@183963|Halobacteria	183963|Halobacteria	N	archaeal flagellar protein F	flaF	-	-	ko:K07329	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_8049507_34	195522.BD01_1144	4.672e-21	98.0	COG3354@1|root,arCOG01822@2157|Archaea,2XYG6@28890|Euryarchaeota,2445A@183968|Thermococci	183968|Thermococci	N	Archaebacterial flagellin	-	-	-	ko:K07330	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_8049507_22	589924.Ferp_1461	9.032e-39	153.0	COG2874@1|root,arCOG04148@2157|Archaea,2XUMD@28890|Euryarchaeota,246RT@183980|Archaeoglobi	183980|Archaeoglobi	N	KaiC	-	-	-	ko:K07331	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ATPase
DPH1_k127_8049507_2	243232.MJ_0900	2.795e-179	576.0	COG4962@1|root,arCOG01817@2157|Archaea,2XTDM@28890|Euryarchaeota,23Q0D@183939|Methanococci	183939|Methanococci	N	PFAM Type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DPH1_k127_8049507_5	573063.Metin_1102	3.844e-167	544.0	COG4962@1|root,arCOG01817@2157|Archaea,2XTDM@28890|Euryarchaeota,23Q0D@183939|Methanococci	183939|Methanococci	N	PFAM Type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DPH1_k127_8049507_11	589924.Ferp_1463	8.33e-83	297.0	COG1955@1|root,arCOG01809@2157|Archaea,2XTAX@28890|Euryarchaeota,246UJ@183980|Archaeoglobi	183980|Archaeoglobi	N	PFAM Type II secretion system F domain	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DPH1_k127_8049507_24	529709.PYCH_12430	2.082e-35	144.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota,243H1@183968|Thermococci	183968|Thermococci	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB3	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_8049507_23	419665.Maeo_0258	2.032e-38	152.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota,23Q8P@183939|Methanococci	183939|Methanococci	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB2	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_8088518_70	86049.XP_008722638.1	5.945e-15	87.0	29CJI@1|root,2RJPB@2759|Eukaryota,38BXG@33154|Opisthokonta,3NXGN@4751|Fungi,3RJ8Y@4890|Ascomycota,20T0Y@147545|Eurotiomycetes,3MYME@451870|Chaetothyriomycetidae	4751|Fungi	S	Vacuolar protein sorting-associated protein 62	VPS62	GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006605,GO:0006623,GO:0006810,GO:0006886,GO:0007034,GO:0008104,GO:0008150,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0031090,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072665,GO:0072666,GO:0098588,GO:0098805,GO:0098852	-	-	-	-	-	-	-	-	-	-	Vps62
DPH1_k127_8088518_4	1449126.JQKL01000061_gene1910	1.322e-273	855.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,2682S@186813|unclassified Clostridiales	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DPH1_k127_8088518_2	1041930.Mtc_2238	2.283e-289	916.0	COG0188@1|root,arCOG04367@2157|Archaea,2XTZV@28890|Euryarchaeota,2N95T@224756|Methanomicrobia	224756|Methanomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DPH1_k127_8088518_5	673860.AciM339_0721	5.542e-184	597.0	COG0550@1|root,COG3058@1|root,arCOG01305@1|root,arCOG01305@2157|Archaea,arCOG01527@2157|Archaea,arCOG05634@2157|Archaea,2XU6T@28890|Euryarchaeota,3F2GF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	HHH_5,Intein_splicing,Topoisom_bac,Toprim,zf-C4_Topoisom
DPH1_k127_8088518_44	1042877.GQS_05775	1.778e-51	186.0	COG0041@1|root,arCOG02464@2157|Archaea,2XU0P@28890|Euryarchaeota,24415@183968|Thermococci	183968|Thermococci	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DPH1_k127_8088518_10	1236689.MMALV_00370	1.192e-126	413.0	COG0519@1|root,arCOG00085@2157|Archaea,2XT82@28890|Euryarchaeota,3F2I1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaAB	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF692.Mbar_A1178	GMP_synt_C,NAD_synthase
DPH1_k127_8088518_34	673860.AciM339_0429	1.739e-61	217.0	COG0518@1|root,arCOG00087@2157|Archaea,2XT3G@28890|Euryarchaeota,3F2M8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaAA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DPH1_k127_8088518_42	269797.Mbar_A1628	7.167e-55	197.0	COG0163@1|root,arCOG01703@2157|Archaea,2XX3R@28890|Euryarchaeota,2N9MQ@224756|Methanomicrobia	224756|Methanomicrobia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DPH1_k127_8088518_22	439481.Aboo_0770	2.643e-76	264.0	COG1646@1|root,arCOG01085@2157|Archaea,2XTEC@28890|Euryarchaeota,3F2M3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	pcrB	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
DPH1_k127_8088518_45	1236689.MMALV_15550	7.574e-49	184.0	COG0061@1|root,COG0483@1|root,arCOG01348@2157|Archaea,arCOG01349@2157|Archaea,2XTP6@28890|Euryarchaeota	28890|Euryarchaeota	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Inositol_P,NAD_kinase
DPH1_k127_8088518_58	439481.Aboo_0599	2.321e-30	125.0	COG2426@1|root,arCOG01330@2157|Archaea,2XZ2Y@28890|Euryarchaeota,3F3AR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DPH1_k127_8088518_19	269797.Mbar_A1783	1.011e-89	311.0	COG0044@1|root,arCOG00689@2157|Archaea,2XTQU@28890|Euryarchaeota,2N9BT@224756|Methanomicrobia	224756|Methanomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DPH1_k127_8088518_25	243232.MJ_0810	1.379e-70	247.0	COG2078@1|root,arCOG01336@2157|Archaea,2XUAP@28890|Euryarchaeota,23QUW@183939|Methanococci	183939|Methanococci	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
DPH1_k127_8088518_17	673860.AciM339_0753	1.168e-95	355.0	COG1287@1|root,arCOG02044@2157|Archaea,arCOG05365@2157|Archaea,2Y7QJ@28890|Euryarchaeota,3F2NE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Carboxypeptidase regulatory-like domain	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,PMT_2,STT3
DPH1_k127_8088518_23	673860.AciM339_0842	1.461e-75	263.0	COG0462@1|root,arCOG00067@2157|Archaea,2XTA8@28890|Euryarchaeota,3F2FN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
DPH1_k127_8088518_21	645991.Sgly_0856	2.39e-77	273.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia,261F2@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
DPH1_k127_8088518_80	572546.Arcpr_1710	1.207e-07	61.0	arCOG10234@1|root,arCOG10234@2157|Archaea,2Y4PW@28890|Euryarchaeota,24791@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_52	673860.AciM339_1239	1.315e-36	141.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,3F2T0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Peptidyl-tRNA hydrolase PTH2	pth	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
DPH1_k127_8088518_38	351160.RRC158	2.097e-58	212.0	COG1637@1|root,arCOG01304@2157|Archaea,2XUC8@28890|Euryarchaeota	28890|Euryarchaeota	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
DPH1_k127_8088518_7	269797.Mbar_A0976	1.515e-143	467.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,2N983@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in regulation of DNA replication	cdc6-1	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22,Cdc6_C
DPH1_k127_8088518_69	439481.Aboo_1076	2.616e-15	78.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75G@28890|Euryarchaeota,3F3FD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
DPH1_k127_8088518_3	273075.Ta0840	1.244e-276	874.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,241IB@183967|Thermoplasmata	183967|Thermoplasmata	O	Cell division protein 48 (CDC48) domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
DPH1_k127_8088518_36	192952.MM_2798	2.094e-59	222.0	COG1784@1|root,arCOG04469@2157|Archaea,2XSZ3@28890|Euryarchaeota,2N9A6@224756|Methanomicrobia	224756|Methanomicrobia	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K08971	-	-	-	-	ko00000	-	-	-	TctA
DPH1_k127_8088518_74	693661.Arcve_1716	1.817e-11	71.0	COG3612@1|root,arCOG04418@2157|Archaea,2XXT8@28890|Euryarchaeota,2476Z@183980|Archaeoglobi	183980|Archaeoglobi	S	Uncharacterized protein conserved in archaea (DUF2240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2240
DPH1_k127_8088518_85	439481.Aboo_1457	4.003e-06	56.0	arCOG05325@1|root,arCOG05325@2157|Archaea,2Y741@28890|Euryarchaeota,3F3CX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_0	667014.Thein_0024	0.0	1131.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GHH0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DPH1_k127_8088518_24	456442.Mboo_1176	1.007e-74	254.0	COG1945@1|root,arCOG04490@2157|Archaea,2XX0H@28890|Euryarchaeota,2N9J2@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
DPH1_k127_8088518_89	575589.HMPREF0018_01471	0.0003476	52.0	COG3428@1|root,COG3428@2|Bacteria,1N9PB@1224|Proteobacteria,1SBM0@1236|Gammaproteobacteria,3NRPC@468|Moraxellaceae	1236|Gammaproteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
DPH1_k127_8088518_55	439481.Aboo_0077	9.38e-32	128.0	COG1310@1|root,arCOG01139@2157|Archaea,2XWKU@28890|Euryarchaeota,3F2SY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
DPH1_k127_8088518_43	1343739.PAP_09990	7.722e-54	200.0	COG0061@1|root,arCOG01348@2157|Archaea,2XTP6@28890|Euryarchaeota,243E4@183968|Thermococci	183968|Thermococci	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DPH1_k127_8088518_11	693661.Arcve_2050	1.544e-108	364.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,245QU@183980|Archaeoglobi	183980|Archaeoglobi	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
DPH1_k127_8088518_76	1347392.CCEZ01000007_gene2012	1.775e-09	61.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	-	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
DPH1_k127_8088518_46	192952.MM_1007	3.333e-48	179.0	COG1628@1|root,arCOG00928@2157|Archaea,2XXBV@28890|Euryarchaeota,2N9K3@224756|Methanomicrobia	224756|Methanomicrobia	L	Belongs to the UPF0215 family	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
DPH1_k127_8088518_57	439481.Aboo_0489	1.446e-30	122.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_8088518_20	1123274.KB899432_gene2914	4.529e-85	292.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
DPH1_k127_8088518_18	1365176.N186_09505	9.172e-90	308.0	COG3367@1|root,arCOG02828@2157|Archaea,2XS1H@28889|Crenarchaeota	28889|Crenarchaeota	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
DPH1_k127_8088518_16	186497.PF0029	2.044e-99	342.0	arCOG05346@1|root,arCOG05346@2157|Archaea,2XWG1@28890|Euryarchaeota,243XG@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_64	1121033.AUCF01000004_gene5065	3.011e-21	99.0	COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,2TTA3@28211|Alphaproteobacteria,2JRM6@204441|Rhodospirillales	204441|Rhodospirillales	K	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF3335
DPH1_k127_8088518_1	877455.Metbo_0009	1.792e-310	972.0	COG2217@1|root,arCOG02763@1|root,arCOG02764@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,arCOG02764@2157|Archaea,2XT3T@28890|Euryarchaeota,23NJY@183925|Methanobacteria	183925|Methanobacteria	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DPH1_k127_8088518_65	593750.Metfor_1237	3.735e-21	93.0	COG3350@1|root,arCOG04507@2157|Archaea	2157|Archaea	P	PFAM YHS domain	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
DPH1_k127_8088518_37	1160707.AJIK01000024_gene1727	2.05e-58	222.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,26GR6@186818|Planococcaceae	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DPH1_k127_8088518_54	589924.Ferp_1486	7.559e-34	134.0	COG3255@1|root,arCOG01842@2157|Archaea,2XXJM@28890|Euryarchaeota,2468P@183980|Archaeoglobi	183980|Archaeoglobi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
DPH1_k127_8088518_51	439235.Dalk_1155	8.916e-39	162.0	COG1541@1|root,COG1541@2|Bacteria,1QA97@1224|Proteobacteria,43E7Y@68525|delta/epsilon subdivisions,2X5A4@28221|Deltaproteobacteria,2MPD8@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
DPH1_k127_8088518_73	158189.SpiBuddy_2107	5.943e-12	71.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
DPH1_k127_8088518_12	316067.Geob_0965	8.755e-106	367.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
DPH1_k127_8088518_14	555088.DealDRAFT_0893	5.107e-104	353.0	COG1073@1|root,COG1073@2|Bacteria,1TSFY@1239|Firmicutes,24ETS@186801|Clostridia	186801|Clostridia	M	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	CW_binding_2,Cu_amine_oxidN1,DLH,DUF3887,Hydrolase_4,Peptidase_S9
DPH1_k127_8088518_75	935866.JAER01000050_gene875	3.849e-10	72.0	COG2373@1|root,COG2373@2|Bacteria,2HDZF@201174|Actinobacteria,4DTIC@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5
DPH1_k127_8088518_81	439481.Aboo_0271	2.756e-07	63.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,NosD
DPH1_k127_8088518_30	1443111.JASG01000004_gene2214	1.662e-65	243.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TQQH@28211|Alphaproteobacteria,3ZV8V@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
DPH1_k127_8088518_28	368407.Memar_2127	1.056e-65	245.0	COG0642@1|root,arCOG04809@1|root,arCOG04809@2157|Archaea,arCOG06192@2157|Archaea	2157|Archaea	T	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
DPH1_k127_8088518_63	945713.IALB_2132	9.731e-23	102.0	COG0745@1|root,COG0745@2|Bacteria	945713.IALB_2132|-	T	phosphorelay signal transduction system	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
DPH1_k127_8088518_83	1450694.BTS2_3928	1.531e-06	59.0	COG1522@1|root,COG1522@2|Bacteria,1V1DR@1239|Firmicutes,4HFRT@91061|Bacilli,1ZG22@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_8088518_86	330779.Saci_2136	1.129e-05	57.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_IclR,TrmB
DPH1_k127_8088518_61	204669.Acid345_4167	1.471e-26	126.0	COG1520@1|root,COG1520@2|Bacteria,3Y2H2@57723|Acidobacteria,2JM3H@204432|Acidobacteriia	204432|Acidobacteriia	S	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	PQQ_3
DPH1_k127_8088518_66	268739.Nmlp_3271	1.811e-18	97.0	COG0517@1|root,arCOG00601@2157|Archaea,2XT75@28890|Euryarchaeota,23TH8@183963|Halobacteria	183963|Halobacteria	C	COG0517 FOG CBS domain	cbs1	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_8088518_49	945713.IALB_2408	8.83e-43	160.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
DPH1_k127_8088518_82	1121373.KB903632_gene518	6.085e-07	55.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_50	580340.Tlie_0058	1.091e-39	153.0	COG3467@1|root,COG3467@2|Bacteria,3TBB5@508458|Synergistetes	508458|Synergistetes	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
DPH1_k127_8088518_79	1195236.CTER_1496	4.516e-08	66.0	COG1874@1|root,COG1874@2|Bacteria,1TSVM@1239|Firmicutes,24AT8@186801|Clostridia	186801|Clostridia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_71	864051.BurJ1DRAFT_0325	5.138e-14	84.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08162,ko:K08226,ko:K16211	-	-	-	-	ko00000,ko02000	2.A.1.2.21,2.A.1.41,2.A.2.6	-	-	MFS_1,PUCC
DPH1_k127_8088518_78	485914.Hmuk_1119	1.104e-08	68.0	arCOG07561@1|root,arCOG07561@2157|Archaea,2XV3J@28890|Euryarchaeota,23UWG@183963|Halobacteria	183963|Halobacteria	K	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_84	246969.TAM4_1430	3.857e-06	59.0	arCOG07561@1|root,arCOG07561@2157|Archaea,2Y6BA@28890|Euryarchaeota,243U4@183968|Thermococci	183968|Thermococci	K	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_31	374847.Kcr_0638	7.494e-65	241.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DPH1_k127_8088518_67	247490.KSU1_C0730	1.16e-17	96.0	COG2234@1|root,COG3291@1|root,COG3420@1|root,COG4409@1|root,COG5184@1|root,COG5276@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4409@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	iap	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6	ko:K01179,ko:K03929,ko:K09612,ko:K12287,ko:K19701,ko:K19702	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02044	-	CE10,GH5,GH9	-	Beta_helix,Peptidase_M28
DPH1_k127_8088518_26	671143.DAMO_2160	9.848e-70	252.0	COG1373@1|root,COG1373@2|Bacteria	671143.DAMO_2160|-	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	-
DPH1_k127_8088518_32	1499967.BAYZ01000045_gene2673	5.738e-62	228.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DPH1_k127_8088518_29	656519.Halsa_0862	1.137e-65	238.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia	186801|Clostridia	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
DPH1_k127_8088518_68	935948.KE386494_gene869	5.978e-16	89.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,24BZ3@186801|Clostridia,42GGS@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DPH1_k127_8088518_56	1220534.B655_1680	1.198e-31	132.0	COG2129@1|root,arCOG01145@2157|Archaea,2XXMZ@28890|Euryarchaeota,23P3K@183925|Methanobacteria	183925|Methanobacteria	S	Metallophosphoesterase, calcineurin superfamily	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DPH1_k127_8088518_72	224719.Abm4_0203	1.529e-12	73.0	COG1730@1|root,arCOG01341@2157|Archaea,2Y0XZ@28890|Euryarchaeota,23P6V@183925|Methanobacteria	183925|Methanobacteria	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	-	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
DPH1_k127_8088518_15	439481.Aboo_1259	2.62e-103	350.0	COG0552@1|root,arCOG01227@2157|Archaea,2XUBI@28890|Euryarchaeota,3F2GR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DPH1_k127_8088518_48	420247.Msm_0415	1.313e-47	179.0	COG0528@1|root,arCOG00858@2157|Archaea,2XT3U@28890|Euryarchaeota,23NRI@183925|Methanobacteria	183925|Methanobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DPH1_k127_8088518_62	673860.AciM339_1005	1.56e-25	112.0	arCOG05517@1|root,arCOG05517@2157|Archaea,2Y72T@28890|Euryarchaeota,3F3AH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8088518_9	706587.Desti_0486	7.102e-133	432.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42SJQ@68525|delta/epsilon subdivisions,2WPH7@28221|Deltaproteobacteria,2MRF5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
DPH1_k127_8088518_39	387631.Asulf_00439	5.067e-58	213.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,2463R@183980|Archaeoglobi	183980|Archaeoglobi	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_8088518_33	224325.AF_1309	1.566e-61	218.0	COG0170@1|root,arCOG01880@2157|Archaea,2XY6G@28890|Euryarchaeota	28890|Euryarchaeota	I	PFAM phosphatidate cytidylyltransferase	-	-	2.7.1.182	ko:K18678	-	-	R10659	RC00002,RC00017	ko00000,ko01000	-	-	-	-
DPH1_k127_8088518_40	877455.Metbo_0520	1.805e-57	206.0	COG0125@1|root,arCOG01893@2157|Archaea,2XZ7Z@28890|Euryarchaeota,23PMA@183925|Methanobacteria	183925|Methanobacteria	F	thymidylate kinase	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DPH1_k127_8088518_53	1089553.Tph_c27240	1.519e-34	137.0	COG1051@1|root,COG1051@2|Bacteria,1VYE7@1239|Firmicutes,251KK@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DPH1_k127_8088518_47	1395587.P364_0117260	9.277e-48	190.0	COG4188@1|root,COG4188@2|Bacteria,1UZMD@1239|Firmicutes,4HEFX@91061|Bacilli,26SNS@186822|Paenibacillaceae	91061|Bacilli	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
DPH1_k127_8088518_13	589924.Ferp_1510	3.955e-105	349.0	COG0047@1|root,arCOG00102@2157|Archaea,2XTPA@28890|Euryarchaeota,246K3@183980|Archaeoglobi	183980|Archaeoglobi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DPH1_k127_8088518_59	459349.CLOAM1816	8.736e-29	120.0	COG1917@1|root,COG1917@2|Bacteria,2NQ91@2323|unclassified Bacteria	2|Bacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DPH1_k127_8088518_27	926569.ANT_19840	1.094e-67	231.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
DPH1_k127_8088518_60	285535.JOEY01000022_gene745	1.32e-26	112.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
DPH1_k127_8088518_8	237368.SCABRO_02885	5.116e-134	435.0	COG1064@1|root,COG1064@2|Bacteria,2IY4H@203682|Planctomycetes	203682|Planctomycetes	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DPH1_k127_8088518_6	349521.HCH_05736	5.563e-163	530.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XHA4@135619|Oceanospirillales	135619|Oceanospirillales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DPH1_k127_8088518_41	1131462.DCF50_p848	1.69e-55	205.0	COG2020@1|root,COG2020@2|Bacteria,1V0PB@1239|Firmicutes,24AQ6@186801|Clostridia,2643P@186807|Peptococcaceae	186801|Clostridia	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DPH1_k127_8088518_87	858215.Thexy_0655	1.617e-05	50.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42F3X@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
DPH1_k127_8487998_7	926549.KI421517_gene3311	1.028e-45	174.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DPH1_k127_8487998_5	521011.Mpal_1109	4.142e-47	172.0	COG5646@1|root,arCOG09457@2157|Archaea,2Y6W7@28890|Euryarchaeota,2NAY6@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DPH1_k127_8487998_13	351160.RCIX134	4.391e-25	111.0	arCOG05710@1|root,arCOG05710@2157|Archaea,2Y58V@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8487998_0	410358.Mlab_0469	2.043e-118	392.0	arCOG01917@1|root,arCOG01917@2157|Archaea,2Y1UU@28890|Euryarchaeota	28890|Euryarchaeota	O	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR,Peptidase_M48,zf-ribbon_3,zinc_ribbon_2
DPH1_k127_8487998_24	397287.C807_01638	3.204e-06	58.0	COG1198@1|root,COG1198@2|Bacteria,1UI22@1239|Firmicutes,25EJI@186801|Clostridia,27UBV@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8487998_25	123214.PERMA_0937	1.035e-05	58.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_8487998_3	1408473.JHXO01000005_gene1750	4.291e-96	321.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,2FSSJ@200643|Bacteroidia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
DPH1_k127_8487998_12	589924.Ferp_0541	1.038e-29	124.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_8487998_17	1128421.JAGA01000001_gene2125	1.769e-13	77.0	28XUM@1|root,2ZJR0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8487998_11	926550.CLDAP_02020	7.897e-34	151.0	COG1520@1|root,COG1520@2|Bacteria,2G93W@200795|Chloroflexi	200795|Chloroflexi	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_8487998_16	1449347.JQLN01000004_gene6098	4.42e-14	87.0	COG3291@1|root,COG3291@2|Bacteria,2I1RE@201174|Actinobacteria,2M51T@2063|Kitasatospora	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Phosphoesterase,fn3
DPH1_k127_8487998_2	368407.Memar_2316	1.222e-102	349.0	COG1541@1|root,arCOG02624@2157|Archaea,2XY74@28890|Euryarchaeota,2NAJN@224756|Methanomicrobia	224756|Methanomicrobia	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
DPH1_k127_8487998_10	1121451.DESAM_23095	7.145e-35	147.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,2MAGK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
DPH1_k127_8487998_21	880073.Calab_1105	3.932e-09	70.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.33.1	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS
DPH1_k127_8487998_15	485914.Hmuk_1505	3.721e-14	85.0	COG3979@1|root,arCOG07452@1|root,arCOG07452@2157|Archaea,arCOG07581@2157|Archaea,2Y0PT@28890|Euryarchaeota	28890|Euryarchaeota	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_8487998_9	9305.ENSSHAP00000004250	2.095e-35	153.0	COG4870@1|root,KOG1543@2759|Eukaryota,38F76@33154|Opisthokonta,3BC68@33208|Metazoa,3D0SI@33213|Bilateria,480RJ@7711|Chordata,496NG@7742|Vertebrata,3JCPB@40674|Mammalia,4K0YY@9263|Metatheria	33208|Metazoa	O	Belongs to the peptidase C1 family	CTSC	GO:0000323,GO:0001775,GO:0001906,GO:0001909,GO:0001913,GO:0002250,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002449,GO:0002456,GO:0002460,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005793,GO:0005794,GO:0005798,GO:0005813,GO:0005815,GO:0005856,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006915,GO:0006955,GO:0006996,GO:0007568,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008236,GO:0009056,GO:0009057,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010952,GO:0012501,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016485,GO:0016504,GO:0016505,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0019899,GO:0019902,GO:0022607,GO:0023051,GO:0023056,GO:0030134,GO:0030135,GO:0030141,GO:0030162,GO:0030163,GO:0030234,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031404,GO:0031410,GO:0031638,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032502,GO:0032940,GO:0033116,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042176,GO:0042221,GO:0042582,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043621,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045732,GO:0045862,GO:0046903,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051087,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0051604,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0052547,GO:0060205,GO:0060255,GO:0061024,GO:0061134,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090114,GO:0097708,GO:0098588,GO:0098772,GO:0099503,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:2001233,GO:2001235	3.4.14.1	ko:K01275	ko04142,ko04210,map04142,map04210	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110,ko04147	-	-	-	CathepsinC_exc,Peptidase_C1
DPH1_k127_8487998_22	694429.Pyrfu_0312	6.109e-08	66.0	COG0778@1|root,arCOG00288@2157|Archaea,2XQMS@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_8487998_20	391623.TERMP_01375	3.379e-11	76.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,242IJ@183968|Thermococci	183968|Thermococci	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_8487998_6	368407.Memar_0892	6.338e-46	173.0	COG3371@1|root,arCOG02008@2157|Archaea,2XWKR@28890|Euryarchaeota,2NBC6@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
DPH1_k127_8487998_23	1238450.VIBNISOn1_1760038	2.561e-06	60.0	COG0705@1|root,COG3809@1|root,COG0705@2|Bacteria,COG3809@2|Bacteria,1MYFP@1224|Proteobacteria,1RSHC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid,zf-TFIIB
DPH1_k127_8487998_4	926569.ANT_15720	2.496e-77	275.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DPH1_k127_8487998_27	1238182.C882_1705	0.0003316	52.0	COG0382@1|root,COG0382@2|Bacteria,1MVS1@1224|Proteobacteria,2TVKN@28211|Alphaproteobacteria,2JPZ0@204441|Rhodospirillales	204441|Rhodospirillales	H	UbiA prenyltransferase family	bchG	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_8487998_19	1453500.AT05_02885	1.257e-11	78.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DPH1_k127_8487998_26	381764.Fnod_0359	2.636e-05	55.0	COG0697@1|root,COG0697@2|Bacteria,2GCQS@200918|Thermotogae	200918|Thermotogae	EG	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
DPH1_k127_8487998_8	1122963.AUHB01000018_gene2056	6.431e-43	166.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria	1224|Proteobacteria	O	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DPH1_k127_8487998_14	1190606.AJYG01000063_gene1316	1.974e-22	111.0	COG5183@1|root,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,1XVD5@135623|Vibrionales	135623|Vibrionales	A	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,TSP_3
DPH1_k127_8487998_1	1192034.CAP_8277	1.752e-110	380.0	COG3266@1|root,COG3266@2|Bacteria,1QZBM@1224|Proteobacteria,42TG7@68525|delta/epsilon subdivisions,2WQPM@28221|Deltaproteobacteria,2Z3I2@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
DPH1_k127_8487998_18	439235.Dalk_2289	3.965e-13	83.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
DPH1_k127_8522040_0	1536772.R70723_07490	6.747e-09	66.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5,RHS_repeat
DPH1_k127_8827161_12	192952.MM_3318	0.0001765	53.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_8827161_8	1484460.JSWG01000015_gene880	2.694e-32	142.0	COG5621@1|root,COG5621@2|Bacteria,4NWAB@976|Bacteroidetes,1I7FM@117743|Flavobacteriia	976|Bacteroidetes	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
DPH1_k127_8827161_5	1167006.UWK_02139	5.016e-81	293.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2MMMU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DPH1_k127_8827161_7	926560.KE387023_gene3745	7.317e-35	152.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.15	ko:K01365,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00537,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I42,Peptidase_C1
DPH1_k127_8827161_11	1197477.IA57_08545	2.671e-06	59.0	COG1522@1|root,COG1522@2|Bacteria,4NNMR@976|Bacteroidetes,1I21F@117743|Flavobacteriia	976|Bacteroidetes	K	COG1522 Transcriptional regulators	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_8827161_10	123214.PERMA_0937	1.302e-08	67.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_8827161_6	415426.Hbut_0158	3.189e-56	203.0	COG1838@1|root,arCOG04406@2157|Archaea,2XQ9V@28889|Crenarchaeota	28889|Crenarchaeota	C	Fe-S type, tartrate fumarate subfamily, beta	-	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
DPH1_k127_8827161_4	1343739.PAP_05865	5.535e-93	313.0	COG1951@1|root,arCOG04407@2157|Archaea,2XUQI@28890|Euryarchaeota,242SI@183968|Thermococci	183968|Thermococci	C	Fumarate hydratase	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
DPH1_k127_8827161_1	386456.JQKN01000002_gene2818	8.16e-275	858.0	COG0365@1|root,arCOG01529@2157|Archaea,2XTAB@28890|Euryarchaeota,23NWY@183925|Methanobacteria	183925|Methanobacteria	I	TIGRFAM Acetate-CoA ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DPH1_k127_8827161_9	673860.AciM339_0022	1.482e-24	116.0	COG1522@1|root,arCOG01580@2157|Archaea,arCOG01585@2157|Archaea,2Y6YT@28890|Euryarchaeota,3F2Y0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8827161_0	56780.SYN_01409	6.836e-285	891.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
DPH1_k127_8827161_2	1128398.Curi_c28890	2.122e-180	572.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,267TT@186813|unclassified Clostridiales	186801|Clostridia	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DPH1_k127_8827161_3	157072.XP_008864029.1	4.599e-131	426.0	COG0045@1|root,KOG1254@2759|Eukaryota	2759|Eukaryota	C	ATP citrate synthase activity	ACLA-3	GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.3.8	ko:K01648	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,map00020,map00720,map01100,map01110,map01120,map01130	-	R00352	RC00004,RC00067	ko00000,ko00001,ko01000,ko04147	-	-	-	ATP-grasp_2,Citrate_bind,Citrate_synt,CoA_binding,Ligase_CoA
DPH1_k127_8948067_65	1236497.BAJQ01000027_gene2361	6.592e-07	60.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes	976|Bacteroidetes	P	COG3420 Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_8948067_25	358396.C445_18396	4.003e-85	306.0	COG2057@1|root,arCOG05316@2157|Archaea,2XW2C@28890|Euryarchaeota,23U50@183963|Halobacteria	183963|Halobacteria	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DPH1_k127_8948067_13	224325.AF_1199	1.075e-134	451.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DPH1_k127_8948067_14	575590.HMPREF0156_00074	1.289e-133	436.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_8948067_3	644282.Deba_2503	2.393e-260	811.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
DPH1_k127_8948067_38	926566.Terro_4081	7.344e-52	199.0	COG0644@1|root,COG0644@2|Bacteria,3Y5JJ@57723|Acidobacteria,2JP4I@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DPH1_k127_8948067_4	1382306.JNIM01000001_gene2570	8.784e-255	794.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DPH1_k127_8948067_54	575588.ACPN01000077_gene1611	6.84e-15	83.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,3NIYP@468|Moraxellaceae	1236|Gammaproteobacteria	I	Biotin carboxylase C-terminal domain	mccA	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
DPH1_k127_8948067_6	96561.Dole_2179	1.694e-165	534.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2MHYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain	pccA	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DPH1_k127_8948067_28	977880.RALTA_A0122	9.821e-71	250.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,1K3TY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
DPH1_k127_8948067_36	1046627.BZARG_1568	3.253e-53	196.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
DPH1_k127_8948067_0	1220534.B655_1659	2.881e-301	946.0	COG0474@1|root,arCOG01578@2157|Archaea,2XW9W@28890|Euryarchaeota	28890|Euryarchaeota	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DPH1_k127_8948067_72	585502.HMPREF0645_0519	0.0004087	53.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,2FMIV@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DPH1_k127_8948067_1	1236689.MMALV_09230	4.299e-270	861.0	COG0495@1|root,arCOG00809@2157|Archaea,2XU7M@28890|Euryarchaeota,3F2EY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
DPH1_k127_8948067_60	1455608.JDTH01000006_gene2664	1.075e-10	76.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD,PQQ_2,PQQ_3
DPH1_k127_8948067_22	374847.Kcr_1277	7.949e-97	333.0	COG2379@1|root,arCOG04170@2157|Archaea	2157|Archaea	G	Glycerate kinase	gck	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
DPH1_k127_8948067_10	673860.AciM339_0085	3.757e-147	479.0	COG0541@1|root,arCOG01228@2157|Archaea,2XTWX@28890|Euryarchaeota,3F2HD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DPH1_k127_8948067_44	429009.Adeg_1212	1.926e-31	132.0	COG0560@1|root,COG0560@2|Bacteria,1VCP5@1239|Firmicutes,24AF0@186801|Clostridia,42IEW@68295|Thermoanaerobacterales	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
DPH1_k127_8948067_58	1121101.HMPREF1532_01912	5.878e-12	78.0	COG4870@1|root,COG4870@2|Bacteria,4PNXD@976|Bacteroidetes,2G101@200643|Bacteroidia	976|Bacteroidetes	O	Propeptide_C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,Propeptide_C25
DPH1_k127_8948067_53	439235.Dalk_2302	3.357e-17	95.0	COG4870@1|root,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria	1224|Proteobacteria	O	PFAM Peptidase C1A, papain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_8948067_52	439481.Aboo_0653	5.501e-18	85.0	COG1958@1|root,arCOG00998@2157|Archaea,2Y0B2@28890|Euryarchaeota,3F2ST@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
DPH1_k127_8948067_5	1379698.RBG1_1C00001G0334	1.06e-227	717.0	COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_0688	Urocanase,Urocanase_C,Urocanase_N
DPH1_k127_8948067_2	1047013.AQSP01000140_gene2469	1.162e-263	819.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DPH1_k127_8948067_47	234267.Acid_7676	1.423e-24	118.0	COG2234@1|root,COG2234@2|Bacteria,3Y43U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DPH1_k127_8948067_11	224325.AF_2316	1.807e-143	471.0	COG1964@1|root,arCOG00933@2157|Archaea,2XTMK@28890|Euryarchaeota,245R2@183980|Archaeoglobi	183980|Archaeoglobi	L	Radical SAM domain protein	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
DPH1_k127_8948067_29	639282.DEFDS_2125	4.062e-70	243.0	COG0036@1|root,COG0036@2|Bacteria,2GEJ9@200930|Deferribacteres	200930|Deferribacteres	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DPH1_k127_8948067_26	70601.3258323	7.573e-76	260.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,24332@183968|Thermococci	183968|Thermococci	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
DPH1_k127_8948067_16	579137.Metvu_0202	8.419e-121	398.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,23QKG@183939|Methanococci	183939|Methanococci	S	TIGRFAM Small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
DPH1_k127_8948067_20	604354.TSIB_1834	1.234e-99	334.0	COG0549@1|root,arCOG00863@2157|Archaea,2XTCB@28890|Euryarchaeota,243F1@183968|Thermococci	183968|Thermococci	E	Belongs to the carbamate kinase family	cpkA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DPH1_k127_8948067_31	647113.Metok_0585	1.542e-67	235.0	COG2518@1|root,arCOG00976@2157|Archaea,2XTRM@28890|Euryarchaeota,23QU4@183939|Methanococci	183939|Methanococci	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DPH1_k127_8948067_32	1499967.BAYZ01000147_gene697	1.103e-60	214.0	COG1839@1|root,COG1839@2|Bacteria,2NPAQ@2323|unclassified Bacteria	2|Bacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
DPH1_k127_8948067_63	123214.PERMA_0937	3.654e-08	65.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_8948067_64	1191523.MROS_0390	1.516e-07	63.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
DPH1_k127_8948067_62	123214.PERMA_0937	3.237e-08	67.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_8948067_59	374847.Kcr_0417	7.951e-12	79.0	arCOG02499@1|root,arCOG02499@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
DPH1_k127_8948067_24	1125699.HMPREF9194_01682	3.702e-85	297.0	COG3875@1|root,COG3875@2|Bacteria,2J6AY@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
DPH1_k127_8948067_49	565033.GACE_1329	2.249e-21	95.0	COG2075@1|root,arCOG01950@2157|Archaea,2Y00Q@28890|Euryarchaeota,246HX@183980|Archaeoglobi	183980|Archaeoglobi	J	Binds to the 23S rRNA	rpl24e	-	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
DPH1_k127_8948067_46	1054217.TALC_00113	4.102e-25	106.0	COG2053@1|root,arCOG04314@2157|Archaea,2XYMV@28890|Euryarchaeota,241VA@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	-	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
DPH1_k127_8948067_42	1343739.PAP_04680	1.256e-37	146.0	COG1358@1|root,arCOG01751@2157|Archaea,2XX4C@28890|Euryarchaeota,2444W@183968|Thermococci	183968|Thermococci	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
DPH1_k127_8948067_21	1054217.TALC_01516	3.017e-97	330.0	COG2108@1|root,arCOG00932@2157|Archaea,2XU78@28890|Euryarchaeota	28890|Euryarchaeota	S	conserved protein related to pyruvate formate-lyase activating enzyme	-	-	-	ko:K07129	-	-	-	-	ko00000	-	-	-	Fer4_14,Radical_SAM
DPH1_k127_8948067_17	368407.Memar_1626	4.658e-115	376.0	COG0863@1|root,arCOG00115@2157|Archaea,2XWB2@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DPH1_k127_8948067_19	1122939.ATUD01000007_gene1986	1.248e-100	343.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CP7E@84995|Rubrobacteria	84995|Rubrobacteria	E	glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DPH1_k127_8948067_34	1047013.AQSP01000105_gene1458	1.592e-57	204.0	2ERMK@1|root,33J72@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
DPH1_k127_8948067_45	1121865.OMW_01738	1.687e-28	121.0	COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli,4AZMS@81852|Enterococcaceae	91061|Bacilli	S	Family of unknown function (DUF438)	XK27_04775	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF438,Hemerythrin,PAS_10
DPH1_k127_8948067_8	1054217.TALC_01304	2.473e-152	496.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,241IU@183967|Thermoplasmata	183967|Thermoplasmata	J	phenylalanine-tRNA ligase activity	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
DPH1_k127_8948067_48	439481.Aboo_0588	1.826e-24	114.0	COG1340@1|root,arCOG01159@2157|Archaea,2Y70M@28890|Euryarchaeota,3F338@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8948067_9	323259.Mhun_0151	5.61e-151	484.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,2N99Q@224756|Methanomicrobia	224756|Methanomicrobia	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,HMG_CoA_synt_N
DPH1_k127_8948067_7	192952.MM_0870	1.586e-159	511.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
DPH1_k127_8948067_40	426368.MmarC7_0460	4.277e-44	164.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,23QWX@183939|Methanococci	183939|Methanococci	V	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DPH1_k127_8948067_66	344747.PM8797T_21828	1.403e-06	63.0	COG1044@1|root,COG2931@1|root,COG4257@1|root,COG1044@2|Bacteria,COG2931@2|Bacteria,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	3.4.24.40	ko:K01406,ko:K02414,ko:K07004,ko:K13277,ko:K21449	ko01503,ko02024,ko02040,map01503,map02024,map02040	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko02035,ko03110	1.B.40.2	-	-	DUF5011,Peptidase_S55,VCBS
DPH1_k127_8948067_50	314345.SPV1_06784	1.32e-20	100.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
DPH1_k127_8948067_67	351160.RRC47	1.632e-06	57.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_11,HTH_24
DPH1_k127_8948067_43	439481.Aboo_1357	2.829e-34	144.0	COG1340@1|root,arCOG01159@2157|Archaea,2XU21@28890|Euryarchaeota,3F2P7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8948067_51	1236689.MMALV_01540	1.306e-18	92.0	COG1813@1|root,arCOG01863@2157|Archaea,2XXND@28890|Euryarchaeota,3F2TJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
DPH1_k127_8948067_41	523845.AQXV01000021_gene1295	8.352e-40	154.0	COG0009@1|root,arCOG01952@2157|Archaea,2XVGC@28890|Euryarchaeota,23QSE@183939|Methanococci	183939|Methanococci	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
DPH1_k127_8948067_27	644281.MFS40622_0392	8.283e-74	258.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,23Q49@183939|Methanococci	183939|Methanococci	J	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DPH1_k127_8948067_39	536232.CLM_3873	3.11e-49	186.0	COG1402@1|root,COG1402@2|Bacteria,1V8P1@1239|Firmicutes,24GAM@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
DPH1_k127_8948067_71	1227352.C173_07262	0.0002498	53.0	COG1075@1|root,COG5492@1|root,COG1075@2|Bacteria,COG5492@2|Bacteria,1VAUC@1239|Firmicutes,4HN5U@91061|Bacilli,26SQP@186822|Paenibacillaceae	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
DPH1_k127_8948067_61	391623.TERMP_00330	2.175e-10	74.0	arCOG01312@1|root,arCOG03256@1|root,arCOG03400@1|root,arCOG01312@2157|Archaea,arCOG03256@2157|Archaea,arCOG03400@2157|Archaea,2Y7MH@28890|Euryarchaeota,243S6@183968|Thermococci	183968|Thermococci	L	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
DPH1_k127_8948067_70	272569.rrnAC3030	2.514e-05	58.0	COG0613@1|root,arCOG01312@1|root,arCOG03264@1|root,arCOG00302@2157|Archaea,arCOG01312@2157|Archaea,arCOG03264@2157|Archaea	2157|Archaea	E	metal-dependent phosphoesterases (PHP family)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,CarboxypepD_reg,DDOST_48kD,PEGA
DPH1_k127_8948067_12	572546.Arcpr_0357	1.395e-139	449.0	COG1899@1|root,arCOG04142@2157|Archaea,2XSTD@28890|Euryarchaeota,2461M@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DPH1_k127_8948067_30	877455.Metbo_0817	2.464e-69	246.0	COG1355@1|root,arCOG01728@2157|Archaea,2XVYU@28890|Euryarchaeota,23P13@183925|Methanobacteria	183925|Methanobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
DPH1_k127_8948067_57	123214.PERMA_0937	2.831e-12	79.0	COG3291@1|root,COG3291@2|Bacteria,2G57S@200783|Aquificae	200783|Aquificae	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_8948067_68	1236689.MMALV_00420	6.353e-06	50.0	arCOG05368@1|root,arCOG05368@2157|Archaea,2Y1EG@28890|Euryarchaeota,3F2W6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8948067_73	572546.Arcpr_1335	0.0005723	46.0	COG4068@1|root,arCOG04390@2157|Archaea,2Y64Z@28890|Euryarchaeota,247EZ@183980|Archaeoglobi	183980|Archaeoglobi	S	Uncharacterized protein containing a Zn-ribbon (DUF2116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
DPH1_k127_8948067_35	420247.Msm_1359	4.117e-54	195.0	COG0503@1|root,arCOG00030@2157|Archaea,2XTWM@28890|Euryarchaeota,23P15@183925|Methanobacteria	183925|Methanobacteria	F	Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis	hpt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
DPH1_k127_8948067_23	420247.Msm_0987	4.199e-95	326.0	COG0076@1|root,arCOG00027@2157|Archaea,2XT09@28890|Euryarchaeota,23PE2@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis	mfnA	-	4.1.1.11,4.1.1.25	ko:K18933	ko00350,ko00410,ko00680,ko00770,ko01100,ko01110,map00350,map00410,map00680,map00770,map01100,map01110	-	R00489,R00736	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
DPH1_k127_8948067_55	439481.Aboo_0090	5.626e-14	76.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75P@28890|Euryarchaeota,3F3FQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
DPH1_k127_8948067_15	545693.BMQ_1616	1.158e-129	426.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,1ZDE5@1386|Bacillus	91061|Bacilli	Q	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU39370	Amidohydro_1,Amidohydro_3
DPH1_k127_8948067_18	1379698.RBG1_1C00001G1247	1.166e-110	365.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
DPH1_k127_8948067_37	857293.CAAU_1751	1.041e-52	193.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,36JRA@31979|Clostridiaceae	186801|Clostridia	E	cyclohydrolase	fchA	-	4.3.1.4	ko:K01746	ko00670,ko01100,map00670,map01100	-	R02302	RC00688	ko00000,ko00001,ko01000	-	-	-	FTCD_C
DPH1_k127_8948067_33	1121918.ARWE01000001_gene215	5.124e-58	209.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,42QYA@68525|delta/epsilon subdivisions,2WNGC@28221|Deltaproteobacteria,43SEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	endonuclease III	nth	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
DPH1_k127_9029051_26	1410624.JNKK01000012_gene2322	8.642e-06	52.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,27NTA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
DPH1_k127_9029051_5	529709.PYCH_16880	4.277e-127	431.0	COG1297@1|root,arCOG04807@2157|Archaea,2XVCD@28890|Euryarchaeota,243GY@183968|Thermococci	183968|Thermococci	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DPH1_k127_9029051_1	439481.Aboo_1077	8.105e-144	467.0	COG1503@1|root,arCOG01742@2157|Archaea,2XSV5@28890|Euryarchaeota,3F2IF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
DPH1_k127_9029051_3	673860.AciM339_0074	8.267e-141	459.0	COG1236@1|root,arCOG00541@2157|Archaea,2XTIU@28890|Euryarchaeota,3F2F9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Beta-Casp domain	epf1	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
DPH1_k127_9029051_6	1094980.Mpsy_1830	1.553e-99	340.0	COG1030@1|root,arCOG01910@2157|Archaea,2XW1R@28890|Euryarchaeota,2NAHP@224756|Methanomicrobia	224756|Methanomicrobia	O	Clp protease	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
DPH1_k127_9029051_8	1094980.Mpsy_1829	6.761e-87	294.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota,2N9RK@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DPH1_k127_9029051_0	608506.COB47_1150	1.945e-151	490.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,42ER3@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DPH1_k127_9029051_9	565033.GACE_0572	4.75e-83	286.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,246MG@183980|Archaeoglobi	183980|Archaeoglobi	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
DPH1_k127_9029051_17	269797.Mbar_A1205	7.434e-39	154.0	COG2178@1|root,arCOG04318@2157|Archaea,2XYD0@28890|Euryarchaeota,2N9Q9@224756|Methanomicrobia	224756|Methanomicrobia	J	RNA-binding protein of the translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
DPH1_k127_9029051_20	604354.TSIB_0138	3.507e-30	126.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,243CN@183968|Thermococci	183968|Thermococci	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbp	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DPH1_k127_9029051_11	673860.AciM339_1025	5.283e-75	257.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,3F2KX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbp	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DPH1_k127_9029051_28	388739.RSK20926_09337	9.995e-05	51.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2U7B2@28211|Alphaproteobacteria,2P4RV@2433|Roseobacter	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_9029051_22	673860.AciM339_1185	5.764e-20	95.0	COG0727@1|root,arCOG02579@2157|Archaea,2Y1J3@28890|Euryarchaeota	28890|Euryarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DPH1_k127_9029051_25	314230.DSM3645_06739	8.224e-07	61.0	COG1572@1|root,COG1572@2|Bacteria,2IYZF@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DPH1_k127_9029051_12	1297617.JPJD01000050_gene1950	1.885e-68	252.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,26944@186813|unclassified Clostridiales	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DPH1_k127_9029051_16	387631.Asulf_00579	8.313e-42	160.0	COG2119@1|root,arCOG03458@2157|Archaea,2XYST@28890|Euryarchaeota,247C2@183980|Archaeoglobi	183980|Archaeoglobi	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
DPH1_k127_9029051_10	1254432.SCE1572_28920	6.118e-78	267.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
DPH1_k127_9029051_23	1265505.ATUG01000001_gene3994	2.752e-14	74.0	arCOG09503@1|root,33HQ7@2|Bacteria,1P8ZZ@1224|Proteobacteria,432Y6@68525|delta/epsilon subdivisions,2WY2H@28221|Deltaproteobacteria,2MP83@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9029051_13	1449063.JMLS01000002_gene1094	1.21e-57	205.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli,274WU@186822|Paenibacillaceae	91061|Bacilli	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
DPH1_k127_9029051_4	593750.Metfor_0715	2.034e-132	434.0	COG0475@1|root,arCOG01953@2157|Archaea,2XV77@28890|Euryarchaeota,2NATR@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DPH1_k127_9029051_19	404380.Gbem_0317	3e-33	133.0	COG1917@1|root,COG1917@2|Bacteria,1MZD8@1224|Proteobacteria,42W0P@68525|delta/epsilon subdivisions,2WRDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DPH1_k127_9029051_14	1459636.NTE_03481	1.423e-49	194.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
DPH1_k127_9029051_15	634498.mru_1953	6.69e-49	187.0	COG0530@1|root,arCOG02881@2157|Archaea,2XVHN@28890|Euryarchaeota,23PNH@183925|Methanobacteria	183925|Methanobacteria	P	K -dependent Na Ca	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DPH1_k127_9029051_24	1189612.A33Q_0666	8.791e-10	71.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DPH1_k127_9029051_18	386456.JQKN01000021_gene35	3.65e-35	136.0	arCOG09714@1|root,arCOG09714@2157|Archaea,2Y0H8@28890|Euryarchaeota,23P85@183925|Methanobacteria	183925|Methanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9029051_21	529709.PYCH_00770	6.638e-27	114.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,244BC@183968|Thermococci	183968|Thermococci	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
DPH1_k127_9029051_7	1237149.C900_03393	4.209e-90	310.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DPH1_k127_9029051_2	352165.HMPREF7215_1007	7.007e-142	461.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DPH1_k127_9029051_27	263358.VAB18032_27071	1.554e-05	50.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
DPH1_k127_9208111_0	391598.FBBAL38_09852	5.156e-119	403.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_9208111_1	1123257.AUFV01000001_gene1597	5.523e-35	145.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1X5UT@135614|Xanthomonadales	135614|Xanthomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DPH1_k127_933922_7	673860.AciM339_0364	6.392e-59	214.0	COG0388@1|root,arCOG00062@2157|Archaea,2XT6R@28890|Euryarchaeota,3F2PP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Carbon-nitrogen hydrolase	-	-	3.5.1.100	ko:K18540	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
DPH1_k127_933922_16	673860.AciM339_0649	1.895e-14	80.0	arCOG03678@1|root,arCOG03678@2157|Archaea,2XZ63@28890|Euryarchaeota,3F2RS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_933922_0	246194.CHY_2385	7.072e-213	674.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,42FHK@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM formate-tetrahydrofolate ligase FTHFS	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
DPH1_k127_933922_2	673860.AciM339_1381	1.38e-87	305.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTGJ@28890|Euryarchaeota,3F2KP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	rpa1	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
DPH1_k127_933922_6	439481.Aboo_1487	1.402e-59	218.0	COG3390@1|root,arCOG02258@2157|Archaea,2Y7QP@28890|Euryarchaeota,3F2PB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	protein conserved in archaea	-	-	-	ko:K09746	-	-	-	-	ko00000	-	-	-	-
DPH1_k127_933922_5	439481.Aboo_1171	4.113e-70	245.0	COG1100@1|root,arCOG01225@2157|Archaea,2XWN4@28890|Euryarchaeota,3F2J6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
DPH1_k127_933922_1	1236689.MMALV_16330	1.873e-137	450.0	COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,3F2H0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A3513	GARS_A,GARS_C,GARS_N
DPH1_k127_933922_8	70601.3257545	7.096e-48	177.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,24401@183968|Thermococci	183968|Thermococci	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
DPH1_k127_933922_4	269797.Mbar_A0315	4.62e-76	264.0	COG0382@1|root,arCOG00476@2157|Archaea,2XWP0@28890|Euryarchaeota,2N9JB@224756|Methanomicrobia	224756|Methanomicrobia	H	UbiA prenyltransferase family	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_933922_13	266117.Rxyl_2895	1.081e-33	139.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4CTPZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
DPH1_k127_933922_14	589924.Ferp_0933	1.716e-18	96.0	COG0640@1|root,arCOG01683@2157|Archaea,2Y0SK@28890|Euryarchaeota,2476X@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DPH1_k127_933922_15	304371.MCP_1644	2.529e-17	83.0	COG1644@1|root,arCOG04244@2157|Archaea,2Y03I@28890|Euryarchaeota,2NA2D@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoN	-	2.7.7.6	ko:K03058	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_N
DPH1_k127_933922_9	589924.Ferp_1963	1.903e-42	159.0	COG0088@1|root,arCOG04243@2157|Archaea,2XWK0@28890|Euryarchaeota,2471N@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the universal ribosomal protein uS9 family	rps9	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DPH1_k127_933922_11	439481.Aboo_1475	4.986e-40	153.0	COG0102@1|root,arCOG04242@2157|Archaea,2XWN6@28890|Euryarchaeota,3F2SC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DPH1_k127_933922_12	439481.Aboo_1474	2.947e-38	147.0	COG1727@1|root,arCOG00780@2157|Archaea,2XZ6R@28890|Euryarchaeota,3F2U4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18,Ribosomal_L27A
DPH1_k127_933922_10	1132855.KB913035_gene1595	3.195e-41	163.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,2VJDE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
DPH1_k127_933922_3	1333523.L593_11785	1.208e-78	276.0	COG1131@1|root,arCOG00196@2157|Archaea,2Y7KH@28890|Euryarchaeota,240TI@183963|Halobacteria	28890|Euryarchaeota	E	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DPH1_k127_933922_17	1123321.KB905813_gene1357	1.573e-13	83.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,2GNGF@201174|Actinobacteria	201174|Actinobacteria	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
DPH1_k127_936217_3	269799.Gmet_2663	6.677e-48	188.0	COG0457@1|root,COG4627@1|root,COG0457@2|Bacteria,COG4627@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
DPH1_k127_936217_6	1254432.SCE1572_45215	1.081e-23	115.0	COG0463@1|root,COG1541@1|root,COG0463@2|Bacteria,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glycos_transf_2
DPH1_k127_936217_5	1293047.CBMA010000008_gene304	2.368e-30	137.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria	183963|Halobacteria	C	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DPH1_k127_936217_4	1236689.MMALV_16230	1.393e-36	148.0	COG1916@1|root,arCOG02142@2157|Archaea,2Y6XP@28890|Euryarchaeota,3F2SA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	TraB family	-	-	-	-	-	-	-	-	-	-	-	-	TraB
DPH1_k127_936217_0	385682.AFSL01000055_gene385	3.562e-239	746.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,2FPWZ@200643|Bacteroidia,3XJY8@558415|Marinilabiliaceae	976|Bacteroidetes	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DPH1_k127_936217_2	439481.Aboo_0318	7.575e-51	188.0	COG1042@1|root,arCOG01338@2157|Archaea,2Y39C@28890|Euryarchaeota,3F35C@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	ATP-grasp domain	-	-	6.2.1.13	ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5
DPH1_k127_936217_1	589924.Ferp_2312	1.216e-177	568.0	COG1541@1|root,arCOG02620@2157|Archaea,2XU3A@28890|Euryarchaeota,245U6@183980|Archaeoglobi	28890|Euryarchaeota	H	PFAM AMP-dependent synthetase	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DPH1_k127_936217_8	192952.MM_3318	1.15e-13	84.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_936217_7	1469557.JSWF01000030_gene3549	1.024e-16	92.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia	976|Bacteroidetes	P	COG3420 Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_9421261_0	439481.Aboo_1543	5.592e-120	392.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
DPH1_k127_9421261_3	497965.Cyan7822_0433	3.528e-06	56.0	COG0235@1|root,COG0235@2|Bacteria,1G59N@1117|Cyanobacteria,3KJA8@43988|Cyanothece	1117|Cyanobacteria	G	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
DPH1_k127_9421261_2	673860.AciM339_0955	5.42e-32	134.0	COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,3F2NI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
DPH1_k127_9421261_1	96561.Dole_2139	1.013e-98	353.0	COG1520@1|root,COG3325@1|root,COG4870@1|root,COG1520@2|Bacteria,COG3325@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,DUF4849,PQQ_2,PQQ_3
DPH1_k127_9566707_60	269797.Mbar_A3372	2.508e-13	81.0	arCOG02497@1|root,arCOG02497@2157|Archaea,2Y7RN@28890|Euryarchaeota,2NBKY@224756|Methanomicrobia	28890|Euryarchaeota	S	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
DPH1_k127_9566707_26	574087.Acear_2228	1.194e-65	227.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WBSS@53433|Halanaerobiales	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
DPH1_k127_9566707_46	589924.Ferp_1102	1.748e-26	113.0	COG4738@1|root,arCOG04377@2157|Archaea,2XYIC@28890|Euryarchaeota,246AV@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9566707_14	439481.Aboo_0452	1.235e-96	328.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTI9@28890|Euryarchaeota,3F2JJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Belongs to the peptidase M24B family	pepQ1	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
DPH1_k127_9566707_45	1459636.NTE_00935	1.912e-29	129.0	COG0053@1|root,arCOG01474@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	cef	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DPH1_k127_9566707_35	386456.JQKN01000010_gene713	5.329e-56	198.0	COG0054@1|root,arCOG01323@2157|Archaea,2XXXC@28890|Euryarchaeota,23P08@183925|Methanobacteria	183925|Methanobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DPH1_k127_9566707_30	1236689.MMALV_10200	5.796e-64	222.0	COG1731@1|root,arCOG01322@2157|Archaea,2XX0K@28890|Euryarchaeota,3F2K2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	6,7-dimethyl-8-ribityllumazine synthase	ribC	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DPH1_k127_9566707_37	673860.AciM339_0317	9.351e-44	165.0	COG0615@1|root,arCOG01222@2157|Archaea,2XX70@28890|Euryarchaeota,3F2RF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme	ribL	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.7.2	ko:K14656	ko00740,ko01100,ko01110,map00740,map01100,map01110	-	R00161	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DPH1_k127_9566707_22	644281.MFS40622_0449	3.836e-72	250.0	COG0108@1|root,arCOG01320@2157|Archaea,2XTDZ@28890|Euryarchaeota,23Q9J@183939|Methanococci	183939|Methanococci	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
DPH1_k127_9566707_57	523850.TON_1230	1.055e-14	76.0	COG1383@1|root,arCOG01885@2157|Archaea,2Y07I@28890|Euryarchaeota,244GA@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eS17 family	rps17e	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
DPH1_k127_9566707_11	1183377.Py04_0274	4.515e-134	439.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,243KU@183968|Thermococci	183968|Thermococci	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
DPH1_k127_9566707_25	192952.MM_1396	4.871e-66	238.0	COG2219@1|root,arCOG03013@2157|Archaea,2XTDT@28890|Euryarchaeota,2N9HY@224756|Methanomicrobia	224756|Methanomicrobia	L	Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priL	-	-	ko:K18882	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_lrg
DPH1_k127_9566707_43	439481.Aboo_0456	1.344e-30	128.0	COG0125@1|root,arCOG01891@2157|Archaea,2XTAM@28890|Euryarchaeota,3F2RW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Thymidylate kinase	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DPH1_k127_9566707_72	933801.Ahos_0670	0.000192	55.0	COG0417@1|root,arCOG00328@2157|Archaea,2XPM8@28889|Crenarchaeota	28889|Crenarchaeota	L	TIGRFAM DNA polymerase (pol2)	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
DPH1_k127_9566707_24	246197.MXAN_5908	5.883e-70	248.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2YUVF@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DPH1_k127_9566707_59	439481.Aboo_0914	1.59e-13	74.0	arCOG06692@1|root,arCOG06692@2157|Archaea,2Y53M@28890|Euryarchaeota,3F3HV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9566707_41	368407.Memar_1691	6.742e-34	136.0	COG1986@1|root,arCOG01223@2157|Archaea,2XWGY@28890|Euryarchaeota,2N9RM@224756|Methanomicrobia	224756|Methanomicrobia	H	TIGRFAM cytidyltransferase-related domain	coaD	-	2.7.7.3	ko:K02201	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DPH1_k127_9566707_62	1294265.JCM21738_431	2.532e-12	80.0	COG3420@1|root,COG3420@2|Bacteria,1UN63@1239|Firmicutes,4HDJ8@91061|Bacilli,1ZRYJ@1386|Bacillus	91061|Bacilli	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_9566707_48	637905.SVI_1922	1.919e-23	117.0	COG3291@1|root,COG5640@1|root,COG3291@2|Bacteria,COG5640@2|Bacteria,1PDUK@1224|Proteobacteria,1S8QS@1236|Gammaproteobacteria,2Q8NA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,Peptidase_M43
DPH1_k127_9566707_58	273075.Ta0785	5.212e-14	79.0	COG3371@1|root,arCOG02008@2157|Archaea,2Y1QQ@28890|Euryarchaeota,242HN@183967|Thermoplasmata	183967|Thermoplasmata	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
DPH1_k127_9566707_38	868131.MSWAN_0037	1.521e-42	165.0	COG3503@1|root,arCOG04370@2157|Archaea,2XWYK@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
DPH1_k127_9566707_31	762982.HMPREF9442_03088	2.793e-59	236.0	COG1520@1|root,COG4870@1|root,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
DPH1_k127_9566707_63	1121403.AUCV01000002_gene452	3.51e-10	74.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,FG-GAP,He_PIG,HemolysinCabind,LVIVD,VWD
DPH1_k127_9566707_42	351160.RCIX562	1.322e-31	145.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9566707_54	415426.Hbut_1285	5.288e-19	91.0	COG0440@1|root,arCOG00811@2157|Archaea,2XR7F@28889|Crenarchaeota	28889|Crenarchaeota	K	Transcriptional regulator, AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_4,MazE_antitoxin,MraZ
DPH1_k127_9566707_68	269797.Mbar_A3630	1.064e-07	64.0	COG0526@1|root,arCOG02498@1|root,arCOG01974@2157|Archaea,arCOG02498@2157|Archaea	2157|Archaea	M	parallel beta-helix repeat	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	NosD,Thioredoxin
DPH1_k127_9566707_53	439481.Aboo_1334	2.366e-19	102.0	arCOG02498@1|root,arCOG02499@1|root,arCOG02545@1|root,arCOG02498@2157|Archaea,arCOG02499@2157|Archaea,arCOG02545@2157|Archaea,2Y6YI@28890|Euryarchaeota,3F2WY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	NosD
DPH1_k127_9566707_28	246969.TAM4_706	2.546e-64	234.0	COG2520@1|root,arCOG00033@2157|Archaea,2XTSI@28890|Euryarchaeota,242WN@183968|Thermococci	183968|Thermococci	J	Met-10+ like-protein	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
DPH1_k127_9566707_71	1094980.Mpsy_1954	6.219e-05	47.0	COG1241@1|root,arCOG02259@2157|Archaea	2157|Archaea	L	DNA replication initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9566707_23	673860.AciM339_0523	3.568e-70	244.0	COG0463@1|root,arCOG00894@2157|Archaea,2XUJ6@28890|Euryarchaeota,3F38U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DPH1_k127_9566707_13	688269.Theth_0425	1.299e-105	355.0	COG0665@1|root,COG0665@2|Bacteria,2GC7R@200918|Thermotogae	200918|Thermotogae	E	PFAM FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
DPH1_k127_9566707_49	69014.TK0121	8.432e-23	100.0	COG0446@1|root,arCOG05745@2157|Archaea,2Y0WP@28890|Euryarchaeota,244HV@183968|Thermococci	183968|Thermococci	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
DPH1_k127_9566707_40	391623.TERMP_00974	5.95e-39	150.0	COG1142@1|root,arCOG05744@2157|Archaea,2XX6H@28890|Euryarchaeota,242UQ@183968|Thermococci	183968|Thermococci	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
DPH1_k127_9566707_9	246969.TAM4_1181	1.344e-144	473.0	COG0446@1|root,arCOG01294@2157|Archaea,2XUFI@28890|Euryarchaeota,242IK@183968|Thermococci	183968|Thermococci	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Pyr_redox_2
DPH1_k127_9566707_44	572546.Arcpr_0981	2.962e-30	124.0	COG0195@1|root,arCOG01760@2157|Archaea,2XYAY@28890|Euryarchaeota,2468I@183980|Archaeoglobi	183980|Archaeoglobi	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
DPH1_k127_9566707_55	387631.Asulf_00700	6.05e-18	86.0	COG1911@1|root,arCOG01752@2157|Archaea,2Y0CU@28890|Euryarchaeota,246FC@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the eukaryotic ribosomal protein eL30 family	rpl30e	-	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
DPH1_k127_9566707_12	673860.AciM339_1400	2.135e-122	408.0	COG0086@1|root,arCOG04256@2157|Archaea,2XTJ6@28890|Euryarchaeota,3F2IB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03042	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Intein_splicing,LAGLIDADG_3,RNA_pol_Rpb1_5
DPH1_k127_9566707_1	673860.AciM339_1401	0.0	1183.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,3F2IK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DPH1_k127_9566707_2	224719.Abm4_0347	0.0	1165.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU1X@28890|Euryarchaeota,23NMQ@183925|Methanobacteria	183925|Methanobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB1	-	2.7.7.6	ko:K03044,ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DPH1_k127_9566707_51	69014.TK1084	1.83e-21	97.0	COG2012@1|root,arCOG04258@2157|Archaea,2Y0EY@28890|Euryarchaeota,244K3@183968|Thermococci	183968|Thermococci	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
DPH1_k127_9566707_33	673860.AciM339_1056	6.046e-59	211.0	COG0602@1|root,arCOG02173@2157|Archaea,2XUSP@28890|Euryarchaeota,3F2KS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
DPH1_k127_9566707_16	572546.Arcpr_0509	4.863e-90	302.0	COG0638@1|root,arCOG00971@2157|Archaea,2XUKA@28890|Euryarchaeota,246RW@183980|Archaeoglobi	183980|Archaeoglobi	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmA	GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
DPH1_k127_9566707_21	439481.Aboo_0184	6.411e-74	255.0	COG1500@1|root,arCOG04187@2157|Archaea,2XTNH@28890|Euryarchaeota,3F2JN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
DPH1_k127_9566707_29	673860.AciM339_0867	3.653e-64	227.0	COG1097@1|root,arCOG00678@2157|Archaea,2XWEN@28890|Euryarchaeota,3F2JY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,KH_1,KH_6,S1
DPH1_k127_9566707_15	273116.14324525	6.647e-92	308.0	COG0689@1|root,arCOG01575@2157|Archaea,2XVHI@28890|Euryarchaeota,241MB@183967|Thermoplasmata	183967|Thermoplasmata	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	-	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DPH1_k127_9566707_18	195522.BD01_2094	1.74e-78	273.0	COG2123@1|root,arCOG01574@2157|Archaea,2XWTK@28890|Euryarchaeota,2433E@183968|Thermococci	183968|Thermococci	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DPH1_k127_9566707_47	342949.PNA2_0520	2.981e-25	108.0	COG1997@1|root,arCOG04208@2157|Archaea,2XYWD@28890|Euryarchaeota,244K8@183968|Thermococci	183968|Thermococci	J	binds to the 23S rRNA	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
DPH1_k127_9566707_65	1094980.Mpsy_2732	9.192e-09	57.0	COG1996@1|root,arCOG04341@2157|Archaea,2XZUD@28890|Euryarchaeota,2NA5N@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoP	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	DNA_RNApol_7kD
DPH1_k127_9566707_69	386456.JQKN01000001_gene1684	2.358e-05	49.0	COG2892@1|root,arCOG04414@2157|Archaea,2Y1HA@28890|Euryarchaeota,23P8R@183925|Methanobacteria	183925|Methanobacteria	S	Transcription factor Pcc1	-	-	-	ko:K09741	-	-	-	-	ko00000,ko03016	-	-	-	Pcc1
DPH1_k127_9566707_8	879309.HMPREF9199_1905	3.504e-146	474.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H24N@909932|Negativicutes	909932|Negativicutes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DPH1_k127_9566707_39	331678.Cphamn1_1489	5.008e-39	150.0	COG1765@1|root,COG1765@2|Bacteria,1FE41@1090|Chlorobi	1090|Chlorobi	O	PFAM OsmC family protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
DPH1_k127_9566707_3	429009.Adeg_1885	0.0	1033.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,42FJG@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
DPH1_k127_9566707_61	485916.Dtox_1351	3.054e-13	78.0	COG1150@1|root,COG1150@2|Bacteria,1V8UM@1239|Firmicutes,24J4U@186801|Clostridia,2622W@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
DPH1_k127_9566707_52	706587.Desti_0171	2.156e-21	102.0	COG1150@1|root,COG1150@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitrate reductase gamma subunit	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DPH1_k127_9566707_19	485915.Dret_0419	6.008e-76	269.0	COG1035@1|root,COG1152@1|root,COG1035@2|Bacteria,COG1152@2|Bacteria,1R4GN@1224|Proteobacteria,42P9J@68525|delta/epsilon subdivisions,2WJ9S@28221|Deltaproteobacteria,2MGKM@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_17,FrhB_FdhB_C
DPH1_k127_9566707_27	1125863.JAFN01000001_gene1777	5.737e-65	224.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42TFE@68525|delta/epsilon subdivisions,2WPDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
DPH1_k127_9566707_0	1449126.JQKL01000011_gene3549	0.0	1422.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,267YC@186813|unclassified Clostridiales	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
DPH1_k127_9566707_4	523845.AQXV01000051_gene1217	1.838e-212	678.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
DPH1_k127_9566707_32	439235.Dalk_5067	4.477e-59	216.0	COG2048@1|root,COG2048@2|Bacteria,1RC7G@1224|Proteobacteria,43B85@68525|delta/epsilon subdivisions,2WMVG@28221|Deltaproteobacteria,2MJQR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	heterodisulfide reductase, subunit	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DPH1_k127_9566707_56	1236689.MMALV_13670	4.14e-17	88.0	COG2048@1|root,arCOG00964@2157|Archaea,2XZ7E@28890|Euryarchaeota,3F2WA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
DPH1_k127_9566707_5	909663.KI867150_gene284	3.314e-192	609.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MQ89@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
DPH1_k127_9566707_6	552811.Dehly_0927	2.056e-172	561.0	COG0543@1|root,COG2204@1|root,COG0543@2|Bacteria,COG2204@2|Bacteria,2G7HU@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.3	ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DPH1_k127_9566707_20	237368.SCABRO_02488	1.021e-75	261.0	COG1941@1|root,COG1941@2|Bacteria,2IXWB@203682|Planctomycetes	203682|Planctomycetes	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
DPH1_k127_9566707_7	880073.Calab_0420	2.889e-151	490.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
DPH1_k127_9566707_50	635013.TherJR_0260	1.271e-22	104.0	COG0680@1|root,COG0680@2|Bacteria,1V7KQ@1239|Firmicutes,24IHW@186801|Clostridia,261UJ@186807|Peptococcaceae	1239|Firmicutes	C	hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
DPH1_k127_9566707_34	243231.GSU1615	7.292e-58	218.0	COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,42RCT@68525|delta/epsilon subdivisions,2WKJ9@28221|Deltaproteobacteria,43UJX@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DPH1_k127_9566707_70	1123277.KB893173_gene1533	3.034e-05	49.0	COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes,47RZY@768503|Cytophagia	976|Bacteroidetes	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DPH1_k127_9566707_36	521011.Mpal_1940	7.477e-50	187.0	COG0476@1|root,arCOG01676@2157|Archaea,2XTYV@28890|Euryarchaeota,2N9IZ@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
DPH1_k127_9566707_67	187272.Mlg_0205	2.146e-08	64.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1WYF6@135613|Chromatiales	135613|Chromatiales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DPH1_k127_9566707_73	661478.OP10G_3041	0.0003345	53.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,TIG,Transglut_core
DPH1_k127_9566707_64	868131.MSWAN_0146	2.709e-09	66.0	COG0500@1|root,arCOG01786@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
DPH1_k127_9566707_66	1165096.ARWF01000001_gene221	1.611e-08	66.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2VIWG@28216|Betaproteobacteria,2KNUY@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DPH1_k127_9566707_10	673860.AciM339_1197	2.551e-138	462.0	COG0433@1|root,arCOG00280@2157|Archaea,2Y7MA@28890|Euryarchaeota,3F30Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
DPH1_k127_9566707_17	1220534.B655_1691	2.59e-79	273.0	COG1798@1|root,arCOG04161@2157|Archaea,2XV63@28890|Euryarchaeota,23NX5@183925|Methanobacteria	183925|Methanobacteria	J	S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis	dphB	-	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	-	TP_methylase
## 1591 queries scanned
## Total time (seconds): 6.3965630531311035
## Rate: 248.73 q/s