## Sat Dec 13 10:35:34 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/DPH1_bin.7.fa -m mmseqs --itype genome -o DPH1_bin.7 --output_dir /data/result/bins/wyx/egg/DPH1_bin.7 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DPH1_k127_10001631_0	1236689.MMALV_04960	9.253e-94	319.0	COG0136@1|root,arCOG00494@2157|Archaea,2XTKH@28890|Euryarchaeota	28890|Euryarchaeota	E	aspartate-semialdehyde dehydrogenase	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DPH1_k127_10001631_1	935845.JADQ01000001_gene1168	4.621e-34	148.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,26S1M@186822|Paenibacillaceae	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
DPH1_k127_10008969_4	273116.14325761	6.961e-13	72.0	COG0644@1|root,arCOG00570@2157|Archaea,2XUI9@28890|Euryarchaeota,241PD@183967|Thermoplasmata	183967|Thermoplasmata	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DPH1_k127_10008969_1	1304875.JAFZ01000001_gene1516	2.225e-104	358.0	COG0168@1|root,COG0168@2|Bacteria,3T9WI@508458|Synergistetes	508458|Synergistetes	P	Potassium uptake protein, TrkH family	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DPH1_k127_10008969_0	192952.MM_1162	2.153e-111	374.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,2NA8M@224756|Methanomicrobia	224756|Methanomicrobia	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DPH1_k127_10008969_2	595460.RRSWK_05623	1.126e-50	193.0	COG0451@1|root,COG0451@2|Bacteria,2IX9F@203682|Planctomycetes	203682|Planctomycetes	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
DPH1_k127_10008969_3	46429.BV95_02266	1.469e-23	118.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TWAU@28211|Alphaproteobacteria,2K7JN@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1001372_0	673860.AciM339_1083	9.582e-79	273.0	COG1234@1|root,arCOG00501@2157|Archaea,2XTJ9@28890|Euryarchaeota,3F2KC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
DPH1_k127_1001372_4	589924.Ferp_2229	7.312e-16	79.0	COG1998@1|root,arCOG04183@2157|Archaea,2Y11U@28890|Euryarchaeota,246I6@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
DPH1_k127_1001372_5	523841.HFX_1987	1.405e-10	67.0	COG2004@1|root,arCOG04182@2157|Archaea,2XXXB@28890|Euryarchaeota,23W6E@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eukaryotic ribosomal protein eS24 family	rps24e	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S24e
DPH1_k127_1001372_2	1455608.JDTH01000001_gene3333	3.861e-25	112.0	COG1909@1|root,arCOG04076@2157|Archaea,2XXSG@28890|Euryarchaeota,23W2W@183963|Halobacteria	183963|Halobacteria	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
DPH1_k127_1001372_3	1236689.MMALV_04380	2.066e-17	82.0	COG2093@1|root,arCOG04077@2157|Archaea,2Y6YF@28890|Euryarchaeota,3F2W7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
DPH1_k127_1001372_1	1236689.MMALV_04370	5.131e-67	234.0	COG1095@1|root,arCOG00675@2157|Archaea,2XT6U@28890|Euryarchaeota,3F2MN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397	rpoE1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
DPH1_k127_10061958_4	1150399.AQYK01000002_gene3209	1.02e-33	141.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_10061958_6	1080067.BAZH01000029_gene1425	5.268e-10	72.0	COG2373@1|root,COG3420@1|root,COG2373@2|Bacteria,COG3420@2|Bacteria,1QV7E@1224|Proteobacteria,1SM3U@1236|Gammaproteobacteria,3WZU8@544|Citrobacter	1236|Gammaproteobacteria	P	Bacterial Ig-like domain (group 3)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
DPH1_k127_10061958_0	1499967.BAYZ01000171_gene5616	1.067e-72	253.0	COG4420@1|root,COG4420@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1003)	yejC	-	-	-	-	-	-	-	-	-	-	-	DUF1003
DPH1_k127_10061958_2	761193.Runsl_0175	3.254e-44	170.0	COG0500@1|root,COG2226@2|Bacteria,4NS4G@976|Bacteroidetes,47QCU@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DPH1_k127_10061958_5	1117647.M5M_14702	1.652e-20	108.0	COG3227@1|root,COG3291@1|root,COG3343@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG3343@2|Bacteria,1R3UF@1224|Proteobacteria,1RYBG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG3291 FOG PKD repeat	-	GO:0005575,GO:0005576	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,PPC,Peptidase_M9,Peptidase_M9_N
DPH1_k127_10061958_1	269797.Mbar_A2751	1.676e-62	242.0	arCOG02527@1|root,arCOG02527@2157|Archaea,2Y6XK@28890|Euryarchaeota,2NAMP@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10061958_3	690850.Desaf_2867	3.767e-34	138.0	COG3324@1|root,COG3324@2|Bacteria,1PV0A@1224|Proteobacteria,4367N@68525|delta/epsilon subdivisions,2X9GI@28221|Deltaproteobacteria,2MD8H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
DPH1_k127_10061958_7	439481.Aboo_0153	6.065e-06	59.0	COG1572@1|root,arCOG03999@1|root,arCOG05978@1|root,arCOG02532@2157|Archaea,arCOG03999@2157|Archaea,arCOG05978@2157|Archaea,2Y4KU@28890|Euryarchaeota	28890|Euryarchaeota	E	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
DPH1_k127_10128914_3	456442.Mboo_0064	2.208e-65	235.0	COG3199@1|root,arCOG01350@2157|Archaea,2XUIQ@28890|Euryarchaeota	28890|Euryarchaeota	S	ATP-NAD AcoX kinase	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DPH1_k127_10128914_1	1365176.N186_05795	1.68e-141	461.0	COG1350@1|root,arCOG01432@2157|Archaea,2XQ0U@28889|Crenarchaeota	28889|Crenarchaeota	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DPH1_k127_10128914_0	880073.Calab_3483	5.376e-168	566.0	COG3033@1|root,COG3033@2|Bacteria,2NNZV@2323|unclassified Bacteria	2|Bacteria	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DPH1_k127_10128914_4	1173028.ANKO01000031_gene3928	7.812e-51	206.0	COG1216@1|root,COG3222@1|root,COG1216@2|Bacteria,COG3222@2|Bacteria,1G0X3@1117|Cyanobacteria,1HHXX@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
DPH1_k127_10128914_2	330214.NIDE3701	2.4e-87	310.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
DPH1_k127_10128914_5	1535422.ND16A_1818	1.089e-29	139.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RWN2@1236|Gammaproteobacteria,2Q85J@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DPH1_k127_10153381_0	1123508.JH636453_gene5802	2.267e-15	90.0	COG3210@1|root,COG3391@1|root,COG3827@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3827@2|Bacteria,COG4932@2|Bacteria,2IY8U@203682|Planctomycetes	203682|Planctomycetes	M	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_10186629_3	330214.NIDE3695	1.864e-18	96.0	COG5033@1|root,COG5033@2|Bacteria	2|Bacteria	K	chromatin organization	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,YEATS
DPH1_k127_10186629_0	1379698.RBG1_1C00001G0675	1.256e-109	369.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
DPH1_k127_10186629_2	410358.Mlab_1687	3.157e-37	148.0	arCOG04820@1|root,arCOG04820@2157|Archaea,2XX4W@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
DPH1_k127_10186629_1	1168034.FH5T_12140	1.607e-99	342.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,2FNQZ@200643|Bacteroidia	976|Bacteroidetes	P	potassium uptake protein, TrkH family	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DPH1_k127_10186880_0	32049.SYNPCC7002_A0478	1.919e-08	59.0	COG1867@1|root,COG1867@2|Bacteria,1G30W@1117|Cyanobacteria,1GZUW@1129|Synechococcus	1117|Cyanobacteria	J	N(2),N(2)-dimethylguanosine tRNA methyltransferase	trm1	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
DPH1_k127_10199530_1	1191523.MROS_0413	8.547e-24	110.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
DPH1_k127_10199530_0	941824.TCEL_01542	1.604e-34	144.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,36E1V@31979|Clostridiaceae	186801|Clostridia	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DPH1_k127_10206042_2	1236689.MMALV_16610	3.843e-19	94.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota	28890|Euryarchaeota	C	reductase	hdrD	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
DPH1_k127_10206042_0	1236689.MMALV_04150	1.854e-91	322.0	COG0277@1|root,arCOG00337@2157|Archaea,arCOG00340@2157|Archaea,2XVP5@28890|Euryarchaeota	28890|Euryarchaeota	C	FAD binding domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
DPH1_k127_10206042_1	1392502.JNIO01000008_gene2022	4.773e-44	185.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H408@909932|Negativicutes	909932|Negativicutes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
DPH1_k127_10207513_1	529709.PYCH_12150	1.094e-57	218.0	COG2520@1|root,arCOG00033@2157|Archaea,2XTSI@28890|Euryarchaeota,242WN@183968|Thermococci	183968|Thermococci	J	Met-10+ like-protein	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
DPH1_k127_10207513_0	768710.DesyoDRAFT_0694	4.244e-124	409.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25ZZ5@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DPH1_k127_10207513_2	323259.Mhun_0597	5.054e-26	119.0	COG3291@1|root,arCOG02559@1|root,arCOG06792@1|root,arCOG02508@2157|Archaea,arCOG02559@2157|Archaea,arCOG06792@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_10214652_0	316055.RPE_0115	2.416e-05	56.0	COG0457@1|root,COG2227@1|root,COG0457@2|Bacteria,COG2227@2|Bacteria,1QW6H@1224|Proteobacteria,2TRBZ@28211|Alphaproteobacteria,3JT4B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31,TPR_2,TPR_8
DPH1_k127_10217513_1	192952.MM_2297	6.32e-24	113.0	arCOG01814@1|root,arCOG01814@2157|Archaea,2XT74@28890|Euryarchaeota,2N90N@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10217513_0	192952.MM_2298	3.57e-122	422.0	COG4962@1|root,arCOG01818@2157|Archaea,2XTN5@28890|Euryarchaeota,2N9AG@224756|Methanomicrobia	224756|Methanomicrobia	N	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
DPH1_k127_10248862_0	868131.MSWAN_0582	7.225e-106	357.0	COG0842@1|root,arCOG01463@2157|Archaea,2XWB7@28890|Euryarchaeota,23PY9@183925|Methanobacteria	183925|Methanobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DPH1_k127_10248862_1	868131.MSWAN_0583	5.852e-78	269.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWVA@28890|Euryarchaeota	28890|Euryarchaeota	E	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_10248862_2	670487.Ocepr_0176	5.929e-20	98.0	COG1309@1|root,COG1309@2|Bacteria,1WJRY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
DPH1_k127_10298066_0	1144275.COCOR_02823	6.102e-29	132.0	COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,438TC@68525|delta/epsilon subdivisions,2X45R@28221|Deltaproteobacteria,2YXQM@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DPH1_k127_10298066_1	645991.Sgly_2277	9.47e-28	126.0	COG0648@1|root,COG0648@2|Bacteria,1UZNN@1239|Firmicutes,24A1E@186801|Clostridia,26096@186807|Peptococcaceae	186801|Clostridia	L	PFAM Xylose isomerase-like TIM barrel	Nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
DPH1_k127_10332664_9	449447.MAE_15810	2.566e-09	68.0	COG2866@1|root,COG2866@2|Bacteria,1G1CQ@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DPH1_k127_10332664_5	537013.CLOSTMETH_03140	4.796e-20	103.0	COG0546@1|root,COG0546@2|Bacteria,1VCQH@1239|Firmicutes,24PMC@186801|Clostridia,3WRJF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
DPH1_k127_10332664_0	273075.Ta0577	8.311e-78	276.0	COG0665@1|root,arCOG00755@2157|Archaea,2Y66F@28890|Euryarchaeota,24239@183967|Thermoplasmata	183967|Thermoplasmata	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DPH1_k127_10332664_3	673860.AciM339_1238	1.394e-30	128.0	COG1628@1|root,arCOG00928@2157|Archaea,2XXBV@28890|Euryarchaeota,3F36M@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Belongs to the UPF0215 family	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
DPH1_k127_10332664_2	673860.AciM339_1239	1.255e-34	136.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,3F2T0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Peptidyl-tRNA hydrolase PTH2	pth	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
DPH1_k127_10332664_7	673860.AciM339_1240	4.218e-17	91.0	COG4743@1|root,arCOG02884@2157|Archaea,2Y72F@28890|Euryarchaeota,3F39B@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1616
DPH1_k127_10332664_1	195522.BD01_0289	1.824e-43	173.0	COG0438@1|root,arCOG01403@2157|Archaea,2XYCV@28890|Euryarchaeota,245MP@183968|Thermococci	183968|Thermococci	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_10332664_6	269797.Mbar_A1859	3.167e-19	92.0	COG0526@1|root,arCOG01972@2157|Archaea,2XZVP@28890|Euryarchaeota,2NA27@224756|Methanomicrobia	224756|Methanomicrobia	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
DPH1_k127_10332664_8	570268.ANBB01000063_gene901	1.911e-13	74.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria	201174|Actinobacteria	O	belongs to the thioredoxin family	trxA2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DPH1_k127_10332664_4	1121396.KB893058_gene2553	4.339e-25	109.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42N2F@68525|delta/epsilon subdivisions,2WIZ8@28221|Deltaproteobacteria,2MIW8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
DPH1_k127_10363268_0	671143.DAMO_1208	1.19e-73	255.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DPH1_k127_10363268_3	1122919.KB905556_gene1014	1.373e-06	57.0	COG0864@1|root,COG0864@2|Bacteria,1V5TB@1239|Firmicutes,4HI5G@91061|Bacilli,26XUI@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
DPH1_k127_10363268_2	888056.HMPREF9062_1063	1.841e-14	81.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria,4D50V@85005|Actinomycetales	201174|Actinobacteria	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
DPH1_k127_10363268_1	1235797.C816_04081	7.219e-59	209.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae	186801|Clostridia	I	Psort location Cytoplasmic, score 9.97	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_10374061_0	565033.GACE_0364	5.433e-74	257.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
DPH1_k127_10374061_1	439481.Aboo_0697	1.503e-60	218.0	COG0388@1|root,arCOG00062@2157|Archaea,2XT6R@28890|Euryarchaeota,3F2PP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Carbon-nitrogen hydrolase	-	-	3.5.1.100	ko:K18540	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
DPH1_k127_10376906_0	573064.Mefer_1149	4.289e-97	330.0	COG1243@1|root,arCOG01361@2157|Archaea,2XT9Z@28890|Euryarchaeota,23Q36@183939|Methanococci	183939|Methanococci	K	SMART Elongator protein 3 MiaB NifB	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Acetyltransf_10,Radical_SAM,Radical_SAM_C
DPH1_k127_10376906_2	459349.CLOAM0442	2.371e-05	58.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
DPH1_k127_10376906_1	797114.C475_01951	6.104e-09	70.0	COG1572@1|root,arCOG07561@1|root,arCOG02532@2157|Archaea,arCOG07561@2157|Archaea,2XZY0@28890|Euryarchaeota	28890|Euryarchaeota	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD
DPH1_k127_10412462_6	1458462.JNLK01000001_gene1132	2.512e-11	76.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,27ICB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
DPH1_k127_10412462_5	941824.TCEL_00775	1.501e-12	80.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,36W9X@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5
DPH1_k127_10412462_2	290397.Adeh_0332	2.414e-30	139.0	2EZCD@1|root,33SHS@2|Bacteria,1NSZK@1224|Proteobacteria,42Z6T@68525|delta/epsilon subdivisions,2WTZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10412462_0	290397.Adeh_0332	2.981e-39	161.0	2EZCD@1|root,33SHS@2|Bacteria,1NSZK@1224|Proteobacteria,42Z6T@68525|delta/epsilon subdivisions,2WTZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10412462_1	269797.Mbar_A1599	1.849e-34	143.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota,2N92Q@224756|Methanomicrobia	224756|Methanomicrobia	C	Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit	hdrD	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
DPH1_k127_10412462_7	290397.Adeh_0335	3.787e-10	71.0	COG1139@1|root,COG1139@2|Bacteria	2|Bacteria	C	lactate oxidation	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
DPH1_k127_10412462_11	85643.Tmz1t_4008	6.586e-05	55.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,2VKT4@28216|Betaproteobacteria,2KUVH@206389|Rhodocyclales	206389|Rhodocyclales	C	MauM NapG family ferredoxin-type protein	napG	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4_4,Fer4_7
DPH1_k127_10412462_8	596330.HMPREF0628_1348	5.019e-08	63.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,22G8G@1570339|Peptoniphilaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
DPH1_k127_10412462_4	706587.Desti_0789	5.524e-15	83.0	COG1139@1|root,COG1139@2|Bacteria,1P3FB@1224|Proteobacteria,431GV@68525|delta/epsilon subdivisions,2WW6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron-sulfur cluster binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10412462_10	322159.STER_B1	6.191e-05	54.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli	91061|Bacilli	O	Belongs to the small heat shock protein (HSP20) family	hsp1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DPH1_k127_10412462_9	926554.KI912640_gene1331	2.496e-05	49.0	COG1522@1|root,COG1522@2|Bacteria,1WKF0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_10412462_3	673860.AciM339_0553	1.506e-24	105.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_10431790_0	387631.Asulf_00547	2.844e-58	216.0	COG2237@1|root,arCOG04151@2157|Archaea,2XTV5@28890|Euryarchaeota,2463A@183980|Archaeoglobi	183980|Archaeoglobi	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
DPH1_k127_10452153_0	1457250.BBMO01000001_gene1581	3.594e-97	348.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_10576184_0	673860.AciM339_1505	8.39e-197	637.0	COG1241@1|root,arCOG00439@2157|Archaea,2XT5D@28890|Euryarchaeota,3F2HN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	MCM OB domain	mcm	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	HTH_3,Intein_splicing,LAGLIDADG_3,MCM,MCM_N,MCM_OB
DPH1_k127_10588724_2	484770.UFO1_1183	1.228e-07	61.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_10588724_0	1120985.AUMI01000004_gene1325	6.305e-69	244.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_10588724_1	42256.RradSPS_2354	7.826e-13	70.0	COG4405@1|root,COG4405@2|Bacteria,2IKQP@201174|Actinobacteria	201174|Actinobacteria	I	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
DPH1_k127_10614752_1	1343739.PAP_06735	2.153e-58	213.0	COG2309@1|root,arCOG01890@2157|Archaea,2XU28@28890|Euryarchaeota,243WP@183968|Thermococci	183968|Thermococci	E	Thermophilic metalloprotease (M29)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
DPH1_k127_10614752_3	673860.AciM339_0907	8.942e-15	89.0	COG1361@1|root,arCOG02527@1|root,arCOG02089@2157|Archaea,arCOG02527@2157|Archaea,2Y6ZW@28890|Euryarchaeota,3F314@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10614752_2	1000565.METUNv1_00578	1.548e-36	147.0	COG3404@1|root,COG3404@2|Bacteria,1R781@1224|Proteobacteria,2VUV6@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C,HutD
DPH1_k127_10614752_0	403833.Pmob_0241	1.665e-120	395.0	COG3643@1|root,COG3643@2|Bacteria,2GC70@200918|Thermotogae	200918|Thermotogae	E	PFAM Formiminotransferase domain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
DPH1_k127_10614752_4	1121920.AUAU01000002_gene2121	7.494e-05	46.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria	57723|Acidobacteria	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_10664358_0	304371.MCP_2485	1.119e-24	116.0	arCOG01190@1|root,arCOG01190@2157|Archaea,2XV67@28890|Euryarchaeota	28890|Euryarchaeota	T	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	RIO1
DPH1_k127_10669308_0	756883.Halar_3273	7.483e-09	64.0	COG3398@1|root,arCOG02611@2157|Archaea	2157|Archaea	K	protein conserved in archaea	gntR	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	HTH_24,HTH_5,MarR_2,V4R
DPH1_k127_1068235_0	246969.TAM4_1197	3.395e-144	470.0	COG0148@1|root,arCOG01169@2157|Archaea,2XSXT@28890|Euryarchaeota,243MB@183968|Thermococci	183968|Thermococci	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DPH1_k127_1068235_1	309800.C498_13229	4.556e-18	85.0	COG1370@1|root,arCOG00991@2157|Archaea,2XYFT@28890|Euryarchaeota,23W9Y@183963|Halobacteria	183963|Halobacteria	O	COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit	-	-	-	ko:K07398	-	-	-	-	ko00000	-	-	-	PUA,TGT_C2
DPH1_k127_10696657_2	410359.Pcal_0002	2.427e-22	104.0	COG1474@1|root,arCOG00467@2157|Archaea,2XPXH@28889|Crenarchaeota	28889|Crenarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22,Cdc6_C
DPH1_k127_10696657_1	273116.14324619	5.298e-118	391.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,241ZA@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
DPH1_k127_10696657_0	555079.Toce_1642	3.5e-323	1020.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
DPH1_k127_10702428_4	439481.Aboo_0788	1.089e-18	98.0	COG0705@1|root,arCOG01768@2157|Archaea,2Y70X@28890|Euryarchaeota,3F340@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DPH1_k127_10702428_3	1385514.N782_21445	1.298e-25	117.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,4HRUF@91061|Bacilli,2YABY@289201|Pontibacillus	91061|Bacilli	S	Ligand-binding protein SH3	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DPH1_k127_10702428_2	351160.LRC41	8.794e-64	231.0	COG2309@1|root,arCOG01890@2157|Archaea	2157|Archaea	E	Leucyl aminopeptidase (Aminopeptidase t)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
DPH1_k127_10702428_1	272557.APE_2074.1	9.47e-91	310.0	COG0162@1|root,arCOG01886@2157|Archaea,2XPU5@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
DPH1_k127_10702428_0	1054217.TALC_00617	3.406e-150	494.0	COG0343@1|root,COG1370@1|root,arCOG00989@2157|Archaea,arCOG00991@2157|Archaea,2XTFH@28890|Euryarchaeota,241KS@183967|Thermoplasmata	183967|Thermoplasmata	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	-	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PUA,TGT,TGT_C2
DPH1_k127_10746867_3	477974.Daud_0092	2.047e-40	154.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,260ZH@186807|Peptococcaceae	186801|Clostridia	C	binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
DPH1_k127_10746867_2	706587.Desti_0011	8.818e-55	212.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2WMQ1@28221|Deltaproteobacteria,2MRSP@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
DPH1_k127_10746867_1	706587.Desti_0012	4.274e-100	355.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria,2MR5W@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DPH1_k127_10746867_0	706587.Desti_0013	6.169e-139	456.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,2MRFE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase, alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DPH1_k127_10746867_4	439235.Dalk_1630	5.615e-27	114.0	COG1146@1|root,COG1146@2|Bacteria,1N0QV@1224|Proteobacteria,42U2Z@68525|delta/epsilon subdivisions,2WR58@28221|Deltaproteobacteria,2MM2N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
DPH1_k127_10749392_2	1236689.MMALV_16390	5.608e-83	289.0	COG2108@1|root,arCOG00932@2157|Archaea,2XU78@28890|Euryarchaeota,3F2FA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	4Fe-4S single cluster domain	-	-	-	ko:K07129	-	-	-	-	ko00000	-	-	-	Fer4_14,Radical_SAM
DPH1_k127_10749392_8	1463936.JOJI01000022_gene4832	4.318e-07	64.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
DPH1_k127_10749392_7	448385.sce0507	3.279e-07	64.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10749392_4	643648.Slip_1745	1.864e-45	177.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,42K19@68298|Syntrophomonadaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	iHN637.CLJU_RS18655	ZnuA
DPH1_k127_10749392_3	760568.Desku_3446	3.759e-54	212.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,264Y7@186807|Peptococcaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	zurA	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	iHN637.CLJU_RS15665	ABC_tran
DPH1_k127_10749392_5	909663.KI867150_gene2625	2.247e-45	177.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MRBY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
DPH1_k127_10749392_0	439481.Aboo_0930	1.006e-118	410.0	COG1236@1|root,arCOG00541@2157|Archaea,2XTIU@28890|Euryarchaeota,3F2F9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Beta-Casp domain	epf1	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
DPH1_k127_10749392_1	247490.KSU1_D0543	1.444e-113	382.0	28IU8@1|root,2Z8T0@2|Bacteria,2IXJA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10749392_6	1347368.HG964403_gene4490	4.528e-33	148.0	COG4632@1|root,COG5492@1|root,COG4632@2|Bacteria,COG5492@2|Bacteria,1V706@1239|Firmicutes,4IQJJ@91061|Bacilli	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_10774729_0	693661.Arcve_0212	6.041e-83	289.0	COG0082@1|root,arCOG04133@2157|Archaea,2XT26@28890|Euryarchaeota,245Z4@183980|Archaeoglobi	183980|Archaeoglobi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DPH1_k127_10774729_1	1123322.KB904650_gene1887	2.288e-53	213.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DPH1_k127_10774729_3	1380347.JNII01000010_gene2598	0.0004268	53.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4ESBC@85013|Frankiales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_10774729_2	1054217.TALC_00563	0.0004005	46.0	COG1685@1|root,arCOG01025@2157|Archaea,2XUI2@28890|Euryarchaeota,241WG@183967|Thermoplasmata	183967|Thermoplasmata	E	GHMP kinases N terminal domain	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
DPH1_k127_1078344_5	1121439.dsat_1255	0.0001107	52.0	COG0727@1|root,COG0727@2|Bacteria,1N3F5@1224|Proteobacteria,42T7I@68525|delta/epsilon subdivisions,2WQMI@28221|Deltaproteobacteria,2MBJU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DPH1_k127_1078344_0	868131.MSWAN_1950	7.196e-106	362.0	COG0595@1|root,arCOG00547@2157|Archaea,2XTIB@28890|Euryarchaeota,23PHA@183925|Methanobacteria	183925|Methanobacteria	J	PFAM RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B_2,RMMBL
DPH1_k127_1078344_4	795797.C497_14317	5.459e-20	95.0	COG3388@1|root,arCOG01345@2157|Archaea,2XXVY@28890|Euryarchaeota,23W4Z@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1078344_1	224325.AF_1642	1.536e-94	334.0	COG0124@1|root,arCOG00404@2157|Archaea,2XSYX@28890|Euryarchaeota,2460A@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DPH1_k127_1078344_3	1094980.Mpsy_2854	2.061e-50	193.0	COG0311@1|root,arCOG00034@2157|Archaea,2XTZS@28890|Euryarchaeota,2N9HT@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
DPH1_k127_1078344_2	1382356.JQMP01000003_gene1745	6.1e-57	207.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi,27YZ2@189775|Thermomicrobia	189775|Thermomicrobia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DPH1_k127_10806581_0	673860.AciM339_1575	5.747e-40	158.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota,3F328@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_10806581_1	1121430.JMLG01000013_gene1888	4.49e-19	94.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia,262YV@186807|Peptococcaceae	186801|Clostridia	S	PFAM MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
DPH1_k127_10859625_2	1236689.MMALV_16250	2.684e-38	153.0	COG0560@1|root,arCOG01158@2157|Archaea	2157|Archaea	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase,Hydrolase_3
DPH1_k127_10859625_0	439481.Aboo_0310	2.307e-204	710.0	COG1287@1|root,arCOG00567@1|root,arCOG00567@2157|Archaea,arCOG05365@2157|Archaea,2Y7QJ@28890|Euryarchaeota,3F2NE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Carboxypeptidase regulatory-like domain	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,PMT_2,STT3
DPH1_k127_10859625_1	882.DVU_0283	4.294e-82	283.0	COG0492@1|root,COG0526@1|root,COG0492@2|Bacteria,COG0526@2|Bacteria,1MV15@1224|Proteobacteria,43BCX@68525|delta/epsilon subdivisions,2X6RU@28221|Deltaproteobacteria,2MH5X@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	Thioredoxin domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
DPH1_k127_10859625_4	269799.Gmet_0556	1.811e-25	125.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,43C5A@68525|delta/epsilon subdivisions,2WNBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10859625_3	243231.GSU2914	3.369e-31	144.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,43C5A@68525|delta/epsilon subdivisions,2WNBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10859625_5	568703.LGG_02274	3.274e-05	57.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	prtB	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5
DPH1_k127_10869794_0	1094980.Mpsy_1916	7.936e-118	389.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,2N9G6@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
DPH1_k127_10869794_1	940282.CADQ01000022_gene2143	1.123e-40	155.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2JPE6@204441|Rhodospirillales	204441|Rhodospirillales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DPH1_k127_10870527_2	1232410.KI421416_gene2685	5.439e-64	224.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WQX0@28221|Deltaproteobacteria,43W25@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
DPH1_k127_10870527_7	439481.Aboo_0646	5.651e-18	87.0	COG1522@1|root,arCOG01580@2157|Archaea,2Y746@28890|Euryarchaeota,3F3D8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_10870527_8	1121459.AQXE01000012_gene2286	5.82e-14	77.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria,2M8WX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DPH1_k127_10870527_5	1227484.C471_01449	2.358e-36	152.0	COG0675@1|root,arCOG00679@2157|Archaea,2Y8F9@28890|Euryarchaeota,241A7@183963|Halobacteria	183963|Halobacteria	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
DPH1_k127_10870527_4	667014.Thein_1484	1.951e-36	149.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
DPH1_k127_10870527_3	1048983.EL17_04825	7.788e-48	180.0	COG0500@1|root,COG0500@2|Bacteria,4PPBM@976|Bacteroidetes	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DPH1_k127_10870527_1	344747.PM8797T_10689	5.042e-148	485.0	COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes	203682|Planctomycetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
DPH1_k127_10870527_6	536227.CcarbDRAFT_0447	1.134e-23	108.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
DPH1_k127_10870527_9	244447.XP_008306502.1	1.308e-07	66.0	2CMVA@1|root,2QS6D@2759|Eukaryota,38FIY@33154|Opisthokonta,3B9YT@33208|Metazoa,3CY39@33213|Bilateria,47ZST@7711|Chordata,49NQR@7742|Vertebrata	33208|Metazoa	T	Myomesin-1	MYOM1	-	-	-	-	-	-	-	-	-	-	-	I-set,fn3
DPH1_k127_10870527_10	1227352.C173_08606	2.694e-06	62.0	COG5297@1|root,COG5297@2|Bacteria,1TXPR@1239|Firmicutes,4I6QI@91061|Bacilli,26UAT@186822|Paenibacillaceae	91061|Bacilli	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
DPH1_k127_10870527_0	1094980.Mpsy_3151	6.469e-255	865.0	COG5520@1|root,arCOG03769@1|root,arCOG07561@1|root,arCOG03769@2157|Archaea,arCOG07561@2157|Archaea,arCOG09138@2157|Archaea,2XV3J@28890|Euryarchaeota,2NBAU@224756|Methanomicrobia	224756|Methanomicrobia	K	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10882296_7	1463934.JOCF01000065_gene4281	5.671e-05	56.0	COG3170@1|root,COG3291@1|root,COG3170@2|Bacteria,COG3291@2|Bacteria,2GKNE@201174|Actinobacteria	201174|Actinobacteria	NU	Collagenase	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,PPC,Peptidase_M9,Peptidase_M9_N
DPH1_k127_10882296_4	1156844.KB891803_gene2356	1.818e-11	78.0	COG1572@1|root,COG1572@2|Bacteria,2H1Z9@201174|Actinobacteria	201174|Actinobacteria	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C,Pectate_lyase_3
DPH1_k127_10882296_5	1236689.MMALV_02530	1.84e-08	60.0	arCOG06958@1|root,arCOG06958@2157|Archaea,2Y41U@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_10882296_3	224325.AF_0280	3.115e-14	77.0	COG3269@1|root,arCOG01641@2157|Archaea,2Y1N9@28890|Euryarchaeota,247FC@183980|Archaeoglobi	183980|Archaeoglobi	S	TRAM domain	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
DPH1_k127_10882296_2	1449343.JQLQ01000002_gene1191	6.352e-20	97.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,27FYA@186828|Carnobacteriaceae	91061|Bacilli	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DPH1_k127_10882296_0	693661.Arcve_1684	1.373e-90	306.0	COG0174@1|root,arCOG01909@2157|Archaea,2XSYS@28890|Euryarchaeota,245NJ@183980|Archaeoglobi	183980|Archaeoglobi	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DPH1_k127_10882296_1	1198114.AciX9_2489	2.278e-55	216.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	wcoG	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,PKD
DPH1_k127_10882296_6	304371.MCP_0578	4.051e-05	55.0	COG0642@1|root,arCOG02350@1|root,arCOG06516@1|root,arCOG02350@2157|Archaea,arCOG06192@2157|Archaea,arCOG06516@2157|Archaea,2Y7SS@28890|Euryarchaeota,2NBM1@224756|Methanomicrobia	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_10884055_1	342949.PNA2_0810	6.752e-39	156.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,242PW@183968|Thermococci	183968|Thermococci	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DPH1_k127_10884055_3	304371.MCP_1831	1.112e-15	84.0	COG3612@1|root,arCOG04418@2157|Archaea,2XXT8@28890|Euryarchaeota,2NA4A@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterized protein conserved in archaea (DUF2240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2240
DPH1_k127_10884055_4	485916.Dtox_0756	3.079e-09	69.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,260RZ@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DPH1_k127_10884055_5	523841.HFX_1587	0.0009968	51.0	COG0438@1|root,arCOG06114@2157|Archaea,2XW7X@28890|Euryarchaeota,23UY4@183963|Halobacteria	183963|Halobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
DPH1_k127_10884055_2	673860.AciM339_1207	1.173e-27	113.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75G@28890|Euryarchaeota,3F3FD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
DPH1_k127_10884055_0	263820.PTO0456	7.011e-107	353.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,241IB@183967|Thermoplasmata	183967|Thermoplasmata	O	Cell division protein 48 (CDC48) domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
DPH1_k127_10909510_0	671143.DAMO_1946	7.985e-109	381.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
DPH1_k127_10909510_1	584708.Apau_0310	1.037e-08	59.0	COG3199@1|root,COG3199@2|Bacteria,3T9RA@508458|Synergistetes	508458|Synergistetes	H	PFAM ATP-NAD AcoX kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
DPH1_k127_10922533_1	1121422.AUMW01000006_gene759	2.405e-17	88.0	COG0477@1|root,COG2814@2|Bacteria,1UGP8@1239|Firmicutes,24ENP@186801|Clostridia	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_10922533_0	113355.CM001775_gene1664	1.382e-87	321.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
DPH1_k127_10922533_2	1123501.KB902284_gene2245	0.0001353	49.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,HemolysinCabind
DPH1_k127_1093497_0	118168.MC7420_3051	3.189e-132	463.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DPH1_k127_10959251_3	439481.Aboo_0018	1.611e-06	62.0	COG0457@1|root,arCOG02527@1|root,arCOG07561@1|root,arCOG02527@2157|Archaea,arCOG03032@2157|Archaea,arCOG07561@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8,VWA
DPH1_k127_10959251_4	436229.JOEH01000009_gene4678	1.111e-05	59.0	COG0443@1|root,COG0443@2|Bacteria,2IC7H@201174|Actinobacteria,2NFXF@228398|Streptacidiphilus	201174|Actinobacteria	O	Zinc finger domain	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	DZR,HSP70
DPH1_k127_10959251_2	871968.DESME_07800	1.03e-77	278.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,260K8@186807|Peptococcaceae	186801|Clostridia	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DPH1_k127_10959251_0	292459.STH260	7.837e-94	331.0	COG4756@1|root,COG4756@2|Bacteria,1TR8T@1239|Firmicutes,24AUH@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1646)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1646
DPH1_k127_10959251_1	1173020.Cha6605_4440	1.498e-78	291.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria	1117|Cyanobacteria	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DPH1_k127_10967924_1	1094980.Mpsy_2951	1.89e-22	109.0	COG1148@1|root,COG1908@1|root,arCOG02235@2157|Archaea,arCOG02476@2157|Archaea,2XT3X@28890|Euryarchaeota,2N9AI@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA-2	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_17,Fer4_7,Fer4_9,FlpD,Pyr_redox_2
DPH1_k127_10967924_0	1041930.Mtc_1540	7.128e-103	358.0	COG1855@1|root,arCOG04116@2157|Archaea,2XSZY@28890|Euryarchaeota,2N924@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM PilT protein domain protein	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,PIN,T2SSE
DPH1_k127_10970950_0	483219.LILAB_35455	3.649e-11	78.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,TSP_3
DPH1_k127_10970950_1	1206777.B195_15857	0.000449	46.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	asparaginase	iaaA	-	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DPH1_k127_10976185_3	1261545.MBE-HAL_1748	1.904e-10	65.0	COG0500@1|root,arCOG04583@2157|Archaea,2XTVC@28890|Euryarchaeota,23ST5@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DPH1_k127_10976185_0	1278307.KB906997_gene3067	1.898e-21	110.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria,1S1VC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
DPH1_k127_10976185_2	208439.AJAP_22285	1.016e-10	76.0	COG1572@1|root,COG1572@2|Bacteria,2H1Z9@201174|Actinobacteria,4E216@85010|Pseudonocardiales	201174|Actinobacteria	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C,Pectate_lyase_3
DPH1_k127_10976185_1	1278309.KB907108_gene1558	5.12e-21	110.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria	1224|Proteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
DPH1_k127_10976185_4	368407.Memar_1422	2.354e-08	62.0	COG2897@1|root,arCOG02019@2157|Archaea,2Y76U@28890|Euryarchaeota,2NBE7@224756|Methanomicrobia	224756|Methanomicrobia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DPH1_k127_10981594_0	195522.BD01_0317	1.42e-133	439.0	COG0043@1|root,arCOG01671@2157|Archaea,2XUDW@28890|Euryarchaeota,242S6@183968|Thermococci	183968|Thermococci	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
DPH1_k127_10981594_1	304371.MCP_2990	7.141e-18	94.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTJP@28890|Euryarchaeota,2N93V@224756|Methanomicrobia	224756|Methanomicrobia	L	PFAM nucleic acid binding, OB-fold, tRNA helicase-type	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
DPH1_k127_10981594_2	439481.Aboo_0018	3.775e-07	64.0	COG0457@1|root,arCOG02527@1|root,arCOG07561@1|root,arCOG02527@2157|Archaea,arCOG03032@2157|Archaea,arCOG07561@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8,VWA
DPH1_k127_11016288_0	1236689.MMALV_10120	6.676e-145	471.0	COG0008@1|root,arCOG04302@2157|Archaea,2XSYV@28890|Euryarchaeota,3F2HK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
DPH1_k127_11016288_1	529709.PYCH_02650	2.801e-62	229.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2435A@183968|Thermococci	183968|Thermococci	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DPH1_k127_11020016_1	1457250.BBMO01000001_gene1581	4.301e-102	363.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_11020016_4	1262915.BN574_00399	7.406e-47	178.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DPH1_k127_11020016_5	321332.CYB_1529	3.031e-15	87.0	COG3703@1|root,COG3703@2|Bacteria,1GR03@1117|Cyanobacteria	1117|Cyanobacteria	P	AIG2-like family	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2
DPH1_k127_11020016_0	379066.GAU_1670	4.575e-103	357.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DPH1_k127_11020016_3	1457250.BBMO01000001_gene306	3.6e-65	233.0	COG0697@1|root,arCOG00271@2157|Archaea,2XT64@28890|Euryarchaeota,23TZT@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_11020016_2	1209072.ALBT01000053_gene467	4.13e-81	306.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1FHR7@10|Cellvibrio	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8,SLH
DPH1_k127_11030510_2	439481.Aboo_0448	8.313e-38	152.0	COG2339@1|root,arCOG02985@2157|Archaea	2157|Archaea	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DPH1_k127_11030510_0	771875.Ferpe_2062	1.079e-93	320.0	COG0549@1|root,COG0549@2|Bacteria,2GCB0@200918|Thermotogae	200918|Thermotogae	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DPH1_k127_11030510_1	1236689.MMALV_07190	2.203e-39	159.0	arCOG04973@1|root,arCOG04973@2157|Archaea,2XX73@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11030510_3	1279019.ARQK01000006_gene150	1.601e-08	61.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1WW48@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DPH1_k127_11048877_1	671143.DAMO_0652	1.178e-08	61.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DPH1_k127_11048877_0	671143.DAMO_1208	2.945e-175	556.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DPH1_k127_11071486_6	673860.AciM339_0022	1.39e-05	54.0	COG1522@1|root,arCOG01580@2157|Archaea,arCOG01585@2157|Archaea,2Y6YT@28890|Euryarchaeota,3F2Y0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11071486_2	1094980.Mpsy_1174	2.182e-52	209.0	COG0642@1|root,COG2203@1|root,arCOG02339@1|root,arCOG02376@1|root,arCOG03567@1|root,arCOG02339@2157|Archaea,arCOG02357@2157|Archaea,arCOG02376@2157|Archaea,arCOG03567@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,2NBNI@224756|Methanomicrobia	28890|Euryarchaeota	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_9,sCache_3_3
DPH1_k127_11071486_3	351160.RCIX443	3.912e-31	129.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,2NAXV@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DPH1_k127_11071486_4	58123.JOFJ01000024_gene3457	4.386e-13	78.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria,4EGW0@85012|Streptosporangiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
DPH1_k127_11071486_0	661478.OP10G_2311	3.464e-80	278.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	nosF	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
DPH1_k127_11071486_5	1047013.AQSP01000128_gene415	2.635e-06	60.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2
DPH1_k127_11071486_1	1210884.HG799462_gene8049	1.116e-58	213.0	COG1131@1|root,COG1131@2|Bacteria,2IZ5V@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_11073808_0	633148.Tagg_1095	8.585e-126	417.0	COG0156@1|root,arCOG00113@2157|Archaea,2XPNA@28889|Crenarchaeota	28889|Crenarchaeota	H	pyridoxal phosphate-dependent acyltransferase	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DPH1_k127_11073808_1	593750.Metfor_0088	3.835e-90	310.0	COG3199@1|root,arCOG01350@2157|Archaea,2XUIQ@28890|Euryarchaeota	28890|Euryarchaeota	S	ATP-NAD AcoX kinase	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DPH1_k127_11079164_0	1232449.BAHV02000020_gene1290	3.198e-06	58.0	COG0454@1|root,COG0456@2|Bacteria,1UHVP@1239|Firmicutes,25E4M@186801|Clostridia,26CRN@186813|unclassified Clostridiales	186801|Clostridia	K	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
DPH1_k127_1108060_1	673860.AciM339_1247	2.56e-21	103.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,3F2UC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
DPH1_k127_1108060_0	1236689.MMALV_09870	5.343e-126	422.0	COG0358@1|root,arCOG04281@2157|Archaea,2XTHB@28890|Euryarchaeota,3F2FZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Toprim domain	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
DPH1_k127_11118444_3	1297742.A176_07579	8.802e-15	83.0	COG3170@1|root,COG3170@2|Bacteria,1R2XT@1224|Proteobacteria,43DHQ@68525|delta/epsilon subdivisions,2X8PG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_11118444_4	983917.RGE_17860	0.0002445	46.0	COG2002@1|root,COG2002@2|Bacteria,1PUEQ@1224|Proteobacteria,2VXRM@28216|Betaproteobacteria,1KMSQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PrlF_antitoxin
DPH1_k127_11118444_1	498761.HM1_1170	1.3e-61	227.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
DPH1_k127_11118444_2	1122921.KB898193_gene2485	1.585e-46	178.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,4HFC4@91061|Bacilli,274ZW@186822|Paenibacillaceae	91061|Bacilli	O	sulfate ABC transporter	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
DPH1_k127_11118444_0	1463920.JOGB01000012_gene6561	4.089e-84	295.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
DPH1_k127_1112575_0	883126.HMPREF9710_05210	3.007e-64	231.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,477B7@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_1112575_2	215358.XP_010750775.1	5.325e-10	71.0	KOG0613@1|root,KOG0613@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata,48Y8I@7742|Vertebrata,4A1S0@7898|Actinopterygii	33208|Metazoa	T	Titin-like	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
DPH1_k127_1112575_1	1280001.BAOA01000072_gene2766	3.713e-36	140.0	2E4R1@1|root,32ZJK@2|Bacteria,1N8FZ@1224|Proteobacteria,1SAJ2@1236|Gammaproteobacteria,1XXUY@135623|Vibrionales	135623|Vibrionales	S	Nitrous oxide-stimulated promoter	-	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
DPH1_k127_11165425_1	391623.TERMP_00409	3.312e-40	160.0	COG0101@1|root,arCOG04449@2157|Archaea,2XTH5@28890|Euryarchaeota,242SP@183968|Thermococci	183968|Thermococci	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
DPH1_k127_11165425_3	439481.Aboo_0090	1.687e-20	94.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75P@28890|Euryarchaeota,3F3FQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
DPH1_k127_11165425_0	760568.Desku_3229	3.241e-90	307.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,2608D@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
DPH1_k127_11165425_2	304371.MCP_2072	3.876e-24	113.0	COG1082@1|root,arCOG01895@2157|Archaea	2157|Archaea	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,NeuB,SAF
DPH1_k127_11165425_4	686578.AFFX01000014_gene1896	3e-05	56.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iSFxv_1172.SFxv_0410	UbiA
DPH1_k127_11244848_3	203122.Sde_1294	3.988e-09	68.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,46D2S@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,DUF4347,He_PIG,HemolysinCabind,PA14
DPH1_k127_11244848_1	439481.Aboo_1126	2.836e-67	241.0	COG1632@1|root,arCOG04209@2157|Archaea,2XTJJ@28890|Euryarchaeota,3F2K4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL15 family	rpl15e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
DPH1_k127_11244848_0	667014.Thein_0953	6.086e-74	256.0	COG0177@1|root,COG0177@2|Bacteria,2GH3R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DPH1_k127_11244848_2	459349.CLOAM0891	5.908e-26	123.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
DPH1_k127_1124792_0	521011.Mpal_1222	6.063e-140	452.0	COG0309@1|root,arCOG00636@2157|Archaea,2XTAH@28890|Euryarchaeota	28890|Euryarchaeota	O	AIR synthase related protein domain protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DPH1_k127_1124792_1	521011.Mpal_1221	4.916e-67	234.0	COG1992@1|root,arCOG00021@2157|Archaea,2Y3P5@28890|Euryarchaeota,2NAWT@224756|Methanomicrobia	224756|Methanomicrobia	H	Thiamine-phosphate synthase	-	-	2.5.1.3	ko:K21220	ko00730,ko01100,map00730,map01100	-	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko01000	-	-	-	ThiP_synth
DPH1_k127_11255871_0	1267535.KB906767_gene2002	7.976e-28	116.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TPMT
DPH1_k127_1126312_4	269797.Mbar_A3153	0.0002877	53.0	COG1520@1|root,arCOG02482@2157|Archaea	2157|Archaea	G	COG1520 FOG WD40-like repeat	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	ASH,DUF1573,PQQ_2,PQQ_3
DPH1_k127_1126312_1	68260.JOAY01000022_gene1804	5.738e-32	134.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DPH1_k127_1126312_3	751944.HALDL1_08325	2.18e-16	89.0	COG1183@1|root,arCOG00671@2157|Archaea,2XT0G@28890|Euryarchaeota,23TMI@183963|Halobacteria	183963|Halobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DPH1_k127_1126312_0	673860.AciM339_0768	2.358e-60	214.0	COG1618@1|root,arCOG01034@2157|Archaea,2XX6U@28890|Euryarchaeota,3F2MF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
DPH1_k127_1126312_2	523850.TON_0648	5.642e-25	118.0	COG1867@1|root,arCOG01219@2157|Archaea,2XTUF@28890|Euryarchaeota,243GQ@183968|Thermococci	183968|Thermococci	J	Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups	trm1	GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
DPH1_k127_11325588_0	374847.Kcr_1511	3.61e-38	159.0	COG0513@1|root,arCOG00078@2157|Archaea	2157|Archaea	J	involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
DPH1_k127_11325588_1	593117.TGAM_0970	1.058e-34	153.0	COG0419@1|root,COG2247@1|root,COG2319@1|root,COG5306@1|root,arCOG02559@1|root,arCOG03264@1|root,arCOG00368@2157|Archaea,arCOG00388@2157|Archaea,arCOG02491@2157|Archaea,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG03512@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
DPH1_k127_11340989_1	1111728.ATYS01000021_gene3860	1.023e-06	63.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	von willebrand factor, type A	lapA	-	-	ko:K12549	-	-	-	-	ko00000	-	-	-	Big_3_2,Cadherin_3,Calx-beta,HemolysinCabind,VCBS,VWA,VWA_2
DPH1_k127_11340989_0	696747.NIES39_D01460	9.552e-13	83.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3,CHU_C,DUF11,Gram_pos_anchor,HemolysinCabind
DPH1_k127_11345281_1	357808.RoseRS_3419	2.775e-30	140.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_11345281_0	1120985.AUMI01000004_gene1325	9.951e-71	246.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_11345281_2	1198449.ACAM_0919	3.142e-05	56.0	COG1522@1|root,arCOG01580@2157|Archaea,2XQX5@28889|Crenarchaeota	28889|Crenarchaeota	K	In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway	lysM	-	-	ko:K06154	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DPH1_k127_11350391_6	368407.Memar_0552	0.0001573	54.0	arCOG03260@1|root,arCOG03260@2157|Archaea,2Y7UA@28890|Euryarchaeota,2NAMH@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11350391_3	235985.BBPN01000020_gene6517	7.056e-35	139.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria,2NMFW@228398|Streptacidiphilus	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DPH1_k127_11350391_2	660470.Theba_1794	4.683e-81	280.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2GE2H@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11350391_0	368407.Memar_0659	2.928e-111	369.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N9HU@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM ABC transporter related	-	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
DPH1_k127_11350391_1	593750.Metfor_1119	5.805e-82	295.0	COG0842@1|root,arCOG01463@2157|Archaea,2XXQI@28890|Euryarchaeota,2N9MG@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
DPH1_k127_11350391_4	1304275.C41B8_18231	9.858e-28	114.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DPH1_k127_113889_4	439481.Aboo_1258	0.000308	49.0	COG1730@1|root,arCOG01341@2157|Archaea,2Y6C8@28890|Euryarchaeota,3F2UB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	-	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
DPH1_k127_113889_3	420247.Msm_0703	8.574e-08	59.0	COG2157@1|root,arCOG04175@2157|Archaea	2157|Archaea	J	PFAM Ribosomal LX protein	rplX	-	-	ko:K02944	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18A
DPH1_k127_113889_2	1054217.TALC_00340	1.058e-28	133.0	COG2129@1|root,arCOG01145@2157|Archaea,2XXMZ@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DPH1_k127_113889_0	1094980.Mpsy_1566	6.049e-65	242.0	COG3389@1|root,arCOG04463@2157|Archaea,2XSZT@28890|Euryarchaeota,2N9I2@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART Peptidase A22, presenilin signal peptide	-	-	-	-	-	-	-	-	-	-	-	-	SPP
DPH1_k127_113889_1	269797.Mbar_A1372	8.857e-55	200.0	COG1601@1|root,arCOG01640@2157|Archaea,2XTVZ@28890|Euryarchaeota,2N9JI@224756|Methanomicrobia	224756|Methanomicrobia	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2b	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	TRAM,eIF-5_eIF-2B
DPH1_k127_11407756_2	1385511.N783_05115	9.178e-73	254.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1TQX3@1239|Firmicutes,4HCI6@91061|Bacilli,2Y90R@289201|Pontibacillus	91061|Bacilli	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
DPH1_k127_11407756_6	673860.AciM339_0295	4.939e-46	179.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,3F2N5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	UbiA prenyltransferase family	ubiA	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_11407756_3	439481.Aboo_0770	1.099e-68	243.0	COG1646@1|root,arCOG01085@2157|Archaea,2XTEC@28890|Euryarchaeota,3F2M3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	pcrB	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
DPH1_k127_11407756_5	351160.RRC525	1.252e-57	228.0	COG3356@1|root,arCOG04351@2157|Archaea,2XVEY@28890|Euryarchaeota,2NAJK@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
DPH1_k127_11407756_0	1410668.JNKC01000004_gene43	3.847e-88	296.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,36ES4@31979|Clostridiaceae	186801|Clostridia	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DPH1_k127_11407756_1	660470.Theba_1990	7.328e-82	288.0	COG4591@1|root,COG4591@2|Bacteria,2GD5W@200918|Thermotogae	200918|Thermotogae	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DPH1_k127_11407756_4	1031288.AXAA01000009_gene734	4.698e-58	214.0	COG5012@1|root,COG5012@2|Bacteria,1V5EH@1239|Firmicutes,24HIB@186801|Clostridia,36J2Q@31979|Clostridiaceae	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
DPH1_k127_11441057_2	1236689.MMALV_01620	1.01e-07	54.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
DPH1_k127_11441057_0	760568.Desku_1027	1.273e-56	207.0	COG0491@1|root,COG0491@2|Bacteria,1UZUA@1239|Firmicutes,24CIA@186801|Clostridia,26369@186807|Peptococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DPH1_k127_11441057_3	397278.JOJN01000003_gene1816	1.284e-05	58.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4DRP0@85009|Propionibacteriales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DPH1_k127_11441057_1	521011.Mpal_0019	4.736e-48	185.0	COG0420@1|root,arCOG00397@2157|Archaea,2XWH1@28890|Euryarchaeota	28890|Euryarchaeota	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity	mre11	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
DPH1_k127_11475073_2	444157.Tneu_1635	1.763e-09	64.0	COG1042@1|root,arCOG01340@2157|Archaea,2XPR9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DPH1_k127_11475073_0	1236689.MMALV_13970	3.569e-140	460.0	COG0180@1|root,arCOG01887@2157|Archaea,2XSVC@28890|Euryarchaeota,3F2N6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DPH1_k127_11475073_1	1104324.P186_1108	4.993e-45	178.0	COG0436@1|root,arCOG04333@2157|Archaea,2XQ9N@28889|Crenarchaeota	28889|Crenarchaeota	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DPH1_k127_11475073_3	765869.BDW_09025	9.228e-09	66.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2MTBJ@213481|Bdellovibrionales,2WJEJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_11480828_0	1144305.PMI02_01755	3.918e-05	55.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,2K1FR@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
DPH1_k127_11497382_0	1382359.JIAL01000001_gene437	2.822e-191	616.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DPH1_k127_11497382_2	1042156.CXIVA_01510	2.794e-07	62.0	COG0655@1|root,COG0655@2|Bacteria,1V5DA@1239|Firmicutes,24HQZ@186801|Clostridia,36VWD@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DPH1_k127_11497382_3	273075.Ta1047a	2.42e-06	59.0	arCOG05330@1|root,arCOG05330@2157|Archaea,2Y24Y@28890|Euryarchaeota,242GS@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11497382_1	1415780.JPOG01000001_gene2853	2.685e-14	84.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1X8MB@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DPH1_k127_11504558_0	439481.Aboo_1100	6.939e-136	446.0	COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,3F2H0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A3513	GARS_A,GARS_C,GARS_N
DPH1_k127_11504558_1	926561.KB900617_gene1964	3.805e-78	271.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WAEI@53433|Halanaerobiales	186801|Clostridia	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
DPH1_k127_11504558_2	579137.Metvu_0163	1.384e-47	177.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,23QT7@183939|Methanococci	183939|Methanococci	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
DPH1_k127_11504558_3	1457250.BBMO01000001_gene1423	2.75e-41	159.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,23V6E@183963|Halobacteria	183963|Halobacteria	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
DPH1_k127_11504558_4	439481.Aboo_1330	2.354e-07	59.0	arCOG07412@1|root,arCOG07412@2157|Archaea,2Y0S5@28890|Euryarchaeota,3F2T8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11528097_0	439481.Aboo_1209	1.012e-61	245.0	COG4870@1|root,arCOG02499@1|root,arCOG05978@1|root,arCOG02499@2157|Archaea,arCOG03607@2157|Archaea,arCOG05978@2157|Archaea	2157|Archaea	C	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_5,Kelch_1,NosD,Peptidase_C1,S_layer_C,fn3
DPH1_k127_11528097_4	316067.Geob_0086	4.537e-07	64.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DPH1_k127_11528097_3	243231.GSU2914	4.514e-13	82.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,43C5A@68525|delta/epsilon subdivisions,2WNBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11528097_1	463191.SSEG_07643	1.591e-43	162.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DPH1_k127_11528097_2	304371.MCP_0425	8.489e-25	109.0	COG0716@1|root,arCOG00519@2157|Archaea,2XXTN@28890|Euryarchaeota,2NB5F@224756|Methanomicrobia	224756|Methanomicrobia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
DPH1_k127_11542974_2	1236689.MMALV_16440	4.705e-14	73.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU1X@28890|Euryarchaeota,3F2FW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03044,ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DPH1_k127_11542974_0	439481.Aboo_1091	0.0	1444.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU1X@28890|Euryarchaeota,3F2FW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03044,ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DPH1_k127_11542974_1	673860.AciM339_1401	0.0	1139.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,3F2IK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DPH1_k127_11594603_1	644966.Tmar_1075	2.681e-82	285.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WCFA@538999|Clostridiales incertae sedis	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DPH1_k127_11594603_0	439481.Aboo_1478	1.846e-97	328.0	COG0249@1|root,arCOG02897@2157|Archaea,2XT0M@28890|Euryarchaeota,3F39N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DPH1_k127_11644213_2	384765.SIAM614_05998	2.778e-13	72.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	yvkB	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Phage_integrase,TetR_C_11,TetR_N
DPH1_k127_11644213_0	1336233.JAEH01000002_gene1345	1.212e-24	122.0	COG1750@1|root,COG2931@1|root,COG2982@1|root,COG3210@1|root,COG3897@1|root,COG1750@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG3897@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4347,FG-GAP,Laminin_G_3,Peptidase_S8,VCBS,W_rich_C
DPH1_k127_11644213_1	1144275.COCOR_06089	1.808e-15	92.0	COG2885@1|root,COG4733@1|root,COG2885@2|Bacteria,COG4733@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
DPH1_k127_1166953_0	593750.Metfor_2676	3.967e-26	113.0	COG0863@1|root,arCOG00115@2157|Archaea	2157|Archaea	H	methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DPH1_k127_1166953_1	1278073.MYSTI_05718	2.119e-15	91.0	COG0823@1|root,COG3291@1|root,COG4932@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_11672024_2	1236689.MMALV_10880	2.072e-41	165.0	COG0402@1|root,arCOG00692@2157|Archaea,2XSYB@28890|Euryarchaeota,3F2N3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Amidohydrolase family	guaD2	-	3.5.4.1,3.5.4.3	ko:K01485,ko:K01487	ko00230,ko00240,ko00330,ko01100,map00230,map00240,map00330,map01100	-	R00974,R01411,R01676,R02922	RC00074,RC00204,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DPH1_k127_11672024_0	439481.Aboo_0735	2.379e-65	233.0	COG0517@1|root,arCOG00600@2157|Archaea,2XU4J@28890|Euryarchaeota,3F2PE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	cbs2	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_11672024_1	192952.MM_1388	8.224e-52	201.0	COG0423@1|root,arCOG00405@2157|Archaea,2XSZK@28890|Euryarchaeota,2N999@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM tRNA synthetase, class II (G, H, P and S)	glyS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DPH1_k127_11688026_0	931277.C448_14303	1.21e-58	212.0	COG0013@1|root,arCOG01254@2157|Archaea,2XTZC@28890|Euryarchaeota,23UTP@183963|Halobacteria	183963|Halobacteria	J	metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
DPH1_k127_11693548_0	1041930.Mtc_0357	2.038e-71	245.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,2N9N0@224756|Methanomicrobia	224756|Methanomicrobia	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbpE	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DPH1_k127_11693548_2	456320.Mvol_0807	5.882e-17	89.0	COG2048@1|root,arCOG00964@2157|Archaea,2XXYP@28890|Euryarchaeota,23Q0K@183939|Methanococci	183939|Methanococci	C	heterodisulfide reductase	hdrC1	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8,Fer4_9
DPH1_k127_11693548_1	456320.Mvol_0794	8.616e-55	207.0	COG2048@1|root,arCOG00338@2157|Archaea,2XTWJ@28890|Euryarchaeota,23Q3U@183939|Methanococci	183939|Methanococci	C	heterodisulfide reductase, subunit B	hdrB2	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DPH1_k127_11717663_1	247490.KSU1_C1240	2.164e-68	252.0	COG1924@1|root,COG1924@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DPH1_k127_11717663_2	387631.Asulf_01054	5.79e-55	203.0	COG1924@1|root,arCOG02678@2157|Archaea,2XVMQ@28890|Euryarchaeota,245WU@183980|Archaeoglobi	183980|Archaeoglobi	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DPH1_k127_11717663_0	370438.PTH_0578	5.948e-87	311.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,2609U@186807|Peptococcaceae	186801|Clostridia	E	Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
DPH1_k127_11717663_3	1172190.M947_03105	3.317e-35	152.0	COG0348@1|root,COG0348@2|Bacteria,1Q4BA@1224|Proteobacteria,42Q02@68525|delta/epsilon subdivisions,2YR7B@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_5
DPH1_k127_11717663_4	1089550.ATTH01000001_gene1987	6.206e-12	79.0	COG2866@1|root,COG2931@1|root,COG3291@1|root,COG2866@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,4NKIR@976|Bacteroidetes	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
DPH1_k127_11717663_5	118168.MC7420_7550	0.0003156	48.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
DPH1_k127_11721111_1	192952.MM_3318	1.15e-05	58.0	COG3291@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CarboxypepD_reg,DUF11,DUF4430,NosD,PKD,Prenyltrans
DPH1_k127_11721111_0	1236689.MMALV_10390	3.877e-76	266.0	COG0037@1|root,arCOG00042@2157|Archaea,2XTEZ@28890|Euryarchaeota,3F2HB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	PP-loop family	tuc1	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
DPH1_k127_11722879_2	1047013.AQSP01000144_gene917	1.452e-49	179.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
DPH1_k127_11722879_6	1047013.AQSP01000144_gene918	1.564e-28	117.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.14,2.8.1.7	ko:K00549,ko:K04085,ko:K04487,ko:K08363	ko00270,ko00450,ko00730,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map00730,map01100,map01110,map01230,map04122	M00017	R04405,R07460,R09365,R11528,R11529	RC00035,RC00113,RC01241,RC01789,RC02313	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048,ko03016,ko03029	1.A.72.1	-	-	DUF2249,Rhodanese,TusA
DPH1_k127_11722879_0	118173.KB235914_gene641	4.628e-161	522.0	COG0843@1|root,COG0843@2|Bacteria,1G1ME@1117|Cyanobacteria,1H763@1150|Oscillatoriales	1117|Cyanobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DPH1_k127_11722879_1	309801.trd_A0395	2.505e-63	230.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
DPH1_k127_11722879_4	322710.Avin_00990	1.881e-35	150.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidase subunit	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DPH1_k127_11722879_7	1040987.AZUY01000042_gene93	1.156e-26	127.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MVYW@1224|Proteobacteria,2TS8D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome C oxidase subunit	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C,Cytochrome_CBB3
DPH1_k127_11722879_5	1236689.MMALV_03850	9.371e-34	145.0	COG2016@1|root,arCOG00985@2157|Archaea,2XX1R@28890|Euryarchaeota,3F2SI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K07575	-	-	-	-	ko00000	-	-	-	DUF1947,PUA
DPH1_k127_11722879_3	547144.HydHO_0636	3.53e-46	175.0	COG1793@1|root,COG1793@2|Bacteria	2|Bacteria	L	dna ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
DPH1_k127_11729835_6	1122998.AUHZ01000011_gene567	2.261e-08	66.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_11729835_0	1042877.GQS_03455	1.915e-129	426.0	COG1522@1|root,COG2865@1|root,arCOG01585@2157|Archaea,arCOG03296@2157|Archaea,2XTDV@28890|Euryarchaeota,245GC@183968|Thermococci	183968|Thermococci	K	Putative DNA-binding domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
DPH1_k127_11729835_7	406552.NJ7G_3736	4.833e-08	63.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,23UR0@183963|Halobacteria	183963|Halobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24
DPH1_k127_11729835_4	1210884.HG799476_gene15385	7.986e-41	159.0	COG0241@1|root,COG0241@2|Bacteria,2IZYR@203682|Planctomycetes	203682|Planctomycetes	E	Polynucleotide kinase 3 phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
DPH1_k127_11729835_2	592015.HMPREF1705_00271	7.743e-54	209.0	COG0279@1|root,COG0279@2|Bacteria,3TB1U@508458|Synergistetes	508458|Synergistetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
DPH1_k127_11729835_1	592015.HMPREF1705_00545	4.597e-120	395.0	COG2605@1|root,COG2605@2|Bacteria,3TC8T@508458|Synergistetes	508458|Synergistetes	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DPH1_k127_11729835_5	1457250.BBMO01000001_gene1581	1.326e-17	98.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_11729835_3	1094980.Mpsy_3151	3.942e-46	191.0	COG5520@1|root,arCOG03769@1|root,arCOG07561@1|root,arCOG03769@2157|Archaea,arCOG07561@2157|Archaea,arCOG09138@2157|Archaea,2XV3J@28890|Euryarchaeota,2NBAU@224756|Methanomicrobia	224756|Methanomicrobia	K	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11740423_0	589924.Ferp_1921	3.15e-10	72.0	arCOG06532@1|root,arCOG06532@2157|Archaea,2Y12Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
DPH1_k127_11740423_1	1313421.JHBV01000052_gene192	3.848e-06	58.0	COG3209@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5384@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5384@2|Bacteria,4PPW2@976|Bacteroidetes,1J12N@117747|Sphingobacteriia	2|Bacteria	JMU	domain protein	-	-	3.2.1.4	ko:K01179,ko:K19360,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000,ko03036	1.B.40.2	GH5,GH9	-	FIVAR,LRR_5,Phospholip_A2_3
DPH1_k127_11751361_0	529709.PYCH_13670	7.537e-252	808.0	COG0013@1|root,arCOG01255@2157|Archaea,2XSXB@28890|Euryarchaeota,243PB@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DPH1_k127_11751361_1	697282.Mettu_2033	1.16e-39	152.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XERF@135618|Methylococcales	135618|Methylococcales	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
DPH1_k127_1179572_2	383372.Rcas_3922	9.859e-11	69.0	COG1708@1|root,COG1708@2|Bacteria,2G9B2@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
DPH1_k127_1179572_1	357808.RoseRS_0084	1.773e-13	74.0	COG2250@1|root,COG2250@2|Bacteria,2G997@200795|Chloroflexi	200795|Chloroflexi	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
DPH1_k127_1179572_0	439481.Aboo_1331	3.762e-55	207.0	COG1395@1|root,arCOG04152@2157|Archaea,2XTMG@28890|Euryarchaeota,3F2M0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07728	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
DPH1_k127_11812156_1	1236689.MMALV_16430	9.139e-94	314.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,3F2IK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DPH1_k127_11812156_0	673860.AciM339_1400	3.184e-119	404.0	COG0086@1|root,arCOG04256@2157|Archaea,2XTJ6@28890|Euryarchaeota,3F2IB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03042	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Intein_splicing,LAGLIDADG_3,RNA_pol_Rpb1_5
DPH1_k127_11812156_2	693661.Arcve_1350	3.869e-21	96.0	COG1911@1|root,arCOG01752@2157|Archaea,2Y0CU@28890|Euryarchaeota,246FC@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the eukaryotic ribosomal protein eL30 family	rpl30e	-	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
DPH1_k127_11812156_3	693661.Arcve_1349	1.3e-19	94.0	COG0195@1|root,arCOG01760@2157|Archaea,2XYAY@28890|Euryarchaeota,2468I@183980|Archaeoglobi	183980|Archaeoglobi	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
DPH1_k127_11817893_0	1347368.HG964403_gene4490	3.315e-44	185.0	COG4632@1|root,COG5492@1|root,COG4632@2|Bacteria,COG5492@2|Bacteria,1V706@1239|Firmicutes,4IQJJ@91061|Bacilli	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_11817893_1	459349.CLOAM0313	1.679e-15	87.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,DUF3857,GBS_Bsp-like,Transglut_core
DPH1_k127_11828759_2	416348.Hlac_2835	1.618e-13	81.0	arCOG04518@1|root,arCOG04518@2157|Archaea,2XUD7@28890|Euryarchaeota,23SZS@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,TrmB
DPH1_k127_11828759_1	268739.Nmlp_2649	2.621e-29	128.0	arCOG04041@1|root,arCOG04518@1|root,arCOG04518@2157|Archaea,arCOG07592@2157|Archaea,2Y8F4@28890|Euryarchaeota,241A5@183963|Halobacteria	183963|Halobacteria	S	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_11828759_0	521011.Mpal_0672	2.867e-48	184.0	arCOG02576@1|root,arCOG02576@2157|Archaea,2XZNM@28890|Euryarchaeota,2N9WU@224756|Methanomicrobia	224756|Methanomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DPH1_k127_11828759_3	1202768.JROF01000014_gene1225	3.238e-09	67.0	COG3413@1|root,arCOG02280@2157|Archaea,2XV99@28890|Euryarchaeota,23UEA@183963|Halobacteria	183963|Halobacteria	K	Bacterio-opsin activator HTH	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
DPH1_k127_11833487_5	439481.Aboo_1514	3.336e-13	70.0	COG0255@1|root,arCOG00785@2157|Archaea,2Y1DQ@28890|Euryarchaeota,3F2VT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal L29 protein	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DPH1_k127_11833487_2	1236689.MMALV_14180	2.553e-36	141.0	COG0023@1|root,arCOG04223@2157|Archaea,2XXW5@28890|Euryarchaeota,3F2TV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Translation initiation factor SUI1	tif1a	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DPH1_k127_11833487_6	1033806.HTIA_1944	1.639e-08	63.0	COG1588@1|root,arCOG00784@2157|Archaea,2Y00M@28890|Euryarchaeota,23Y0J@183963|Halobacteria	183963|Halobacteria	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	-	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
DPH1_k127_11833487_3	1041930.Mtc_1332	1.965e-29	121.0	COG0186@1|root,arCOG04096@2157|Archaea,2XYPE@28890|Euryarchaeota,2N9XI@224756|Methanomicrobia	224756|Methanomicrobia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DPH1_k127_11833487_0	439481.Aboo_1511	4.14e-50	183.0	COG0093@1|root,arCOG04095@2157|Archaea,2XWM6@28890|Euryarchaeota,3F2NF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DPH1_k127_11833487_4	272557.APE_0358	2.005e-25	109.0	COG0198@1|root,arCOG04094@2157|Archaea,2XQQB@28889|Crenarchaeota	28889|Crenarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,Ribosomal_L26
DPH1_k127_11833487_1	634498.mru_0864	1.406e-38	149.0	COG1471@1|root,arCOG04093@2157|Archaea,2XT03@28890|Euryarchaeota,23NT9@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	-	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
DPH1_k127_11855171_2	453591.Igni_0753	4.218e-11	69.0	arCOG06454@1|root,arCOG06454@2157|Archaea	2157|Archaea	S	Zc3h12a-like Ribonuclease NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	RNase_Zc3h12a
DPH1_k127_11855171_1	1463921.JODF01000013_gene3826	2.811e-17	95.0	COG0454@1|root,COG0456@2|Bacteria,2I34W@201174|Actinobacteria	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DPH1_k127_11855171_0	1347368.HG964403_gene4490	3.271e-40	173.0	COG4632@1|root,COG5492@1|root,COG4632@2|Bacteria,COG5492@2|Bacteria,1V706@1239|Firmicutes,4IQJJ@91061|Bacilli	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_11855171_3	356851.JOAN01000013_gene5810	0.0003937	54.0	COG2133@1|root,COG3291@1|root,COG3507@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4D8ZK@85008|Micromonosporales	201174|Actinobacteria	G	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1349,GSDH,PKD,ThuA
DPH1_k127_11905092_2	720554.Clocl_2107	3.102e-15	94.0	COG1305@1|root,COG1305@2|Bacteria,1UVFG@1239|Firmicutes,2496A@186801|Clostridia,3WIAW@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,Transglut_core
DPH1_k127_11905092_1	886293.Sinac_7537	2.638e-16	98.0	COG1657@1|root,COG1657@2|Bacteria,2IZ5Q@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
DPH1_k127_11905092_0	493475.GARC_4265	6.152e-26	130.0	COG2931@1|root,COG2982@1|root,COG4733@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG4733@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
DPH1_k127_11958614_1	690850.Desaf_0474	5.934e-67	237.0	COG4912@1|root,COG4912@2|Bacteria,1RGVM@1224|Proteobacteria,437UD@68525|delta/epsilon subdivisions,2WYP2@28221|Deltaproteobacteria,2MCDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DPH1_k127_11958614_0	604331.AUHY01000023_gene1638	1.891e-122	409.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_11958614_2	323259.Mhun_0530	3.856e-21	103.0	arCOG07677@1|root,arCOG07677@2157|Archaea,2XWVM@28890|Euryarchaeota	28890|Euryarchaeota	S	Possible catecholamine-binding domain present in a variety of eukaryotic proteins.	-	-	-	-	-	-	-	-	-	-	-	-	DOMON
DPH1_k127_11971578_0	448385.sce2686	1.631e-47	184.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YU5N@29|Myxococcales	28221|Deltaproteobacteria	T	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
DPH1_k127_12016705_1	1380408.AVGH01000046_gene2871	2.196e-15	88.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,21VRR@150247|Anoxybacillus	91061|Bacilli	CO	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DPH1_k127_12016705_0	1249975.JQLP01000003_gene76	7.242e-28	132.0	COG1361@1|root,COG3266@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1HZAG@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
DPH1_k127_12016705_2	1324957.K933_00632	3.392e-14	85.0	arCOG01314@1|root,arCOG01314@2157|Archaea,2XVNC@28890|Euryarchaeota,23TF3@183963|Halobacteria	183963|Halobacteria	L	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
DPH1_k127_12061403_7	472759.Nhal_1323	4.433e-13	82.0	COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,1S4AZ@1236|Gammaproteobacteria,1X1E5@135613|Chromatiales	135613|Chromatiales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DPH1_k127_12061403_5	765420.OSCT_0802	4.493e-34	148.0	COG0438@1|root,COG0438@2|Bacteria,2GB6D@200795|Chloroflexi,3753H@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DPH1_k127_12061403_4	1324957.K933_00562	4.853e-41	167.0	COG0438@1|root,arCOG01411@2157|Archaea,2Y8BS@28890|Euryarchaeota,2418K@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_12061403_8	1070774.J07HN4v3_01012	4.546e-06	59.0	COG1266@1|root,arCOG02766@2157|Archaea,2XU5W@28890|Euryarchaeota,23TD8@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DPH1_k127_12061403_6	593117.TGAM_2116	1.554e-14	79.0	COG1708@1|root,arCOG01195@2157|Archaea,2Y13F@28890|Euryarchaeota,244EB@183968|Thermococci	183968|Thermococci	S	Nucleotidyltransferase domain	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
DPH1_k127_12061403_2	266117.Rxyl_0494	1.603e-71	253.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4CPGH@84995|Rubrobacteria	201174|Actinobacteria	C	Aldo/keto reductase family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DPH1_k127_12061403_3	485913.Krac_2038	4.321e-68	259.0	COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DPH1_k127_12061403_0	926569.ANT_01290	5.007e-132	428.0	COG0863@1|root,COG0863@2|Bacteria,2G650@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
DPH1_k127_12061403_1	644966.Tmar_1485	7.38e-123	413.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,3WDC4@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DPH1_k127_12068989_0	192952.MM_3076	9.472e-180	590.0	COG0550@1|root,arCOG01527@2157|Archaea,arCOG06233@2157|Archaea,2XU6T@28890|Euryarchaeota,2N96B@224756|Methanomicrobia	224756|Methanomicrobia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	HHH_5,Topoisom_bac,Toprim,zf-C4_Topoisom
DPH1_k127_12068989_1	588581.Cpap_0288	7.662e-32	130.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WIP2@541000|Ruminococcaceae	186801|Clostridia	V	PFAM ABC transporter	yfiL	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DPH1_k127_12084264_1	489825.LYNGBM3L_25540	2.071e-29	129.0	COG1100@1|root,COG1100@2|Bacteria,1G5QQ@1117|Cyanobacteria,1HB5W@1150|Oscillatoriales	1117|Cyanobacteria	S	COG1100 GTPase SAR1 and related small G	-	-	-	-	-	-	-	-	-	-	-	-	Ras,Roc
DPH1_k127_12084264_0	1236689.MMALV_05030	3.098e-71	254.0	COG1537@1|root,arCOG01741@2157|Archaea,2XTQ4@28890|Euryarchaeota,3F2P2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_2,eRF1_3
DPH1_k127_12114517_5	192952.MM_1512	1.251e-10	72.0	arCOG02911@1|root,arCOG02911@2157|Archaea,2Y0M6@28890|Euryarchaeota,2N9ZD@224756|Methanomicrobia	224756|Methanomicrobia	U	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_12114517_2	1122609.AUGT01000008_gene2868	2.67e-18	100.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
DPH1_k127_12114517_4	192952.MM_1507	1.292e-13	85.0	arCOG02914@1|root,arCOG02914@2157|Archaea	2157|Archaea	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_12114517_6	1041930.Mtc_0985	5.587e-05	57.0	arCOG02420@1|root,arCOG02420@2157|Archaea	2157|Archaea	S	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Pilin_N
DPH1_k127_12114517_3	224325.AF_0782	4.363e-14	77.0	COG2450@1|root,arCOG02263@2157|Archaea,2XXYF@28890|Euryarchaeota,2474H@183980|Archaeoglobi	183980|Archaeoglobi	D	Pfam:DUF552	-	-	-	ko:K09152	-	-	-	-	ko00000	-	-	-	SepF
DPH1_k127_12114517_0	1094980.Mpsy_2683	8.053e-148	485.0	COG0172@1|root,arCOG00403@2157|Archaea,2XUK2@28890|Euryarchaeota,2N9B1@224756|Methanomicrobia	224756|Methanomicrobia	J	able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A2126	-
DPH1_k127_12114517_1	1236689.MMALV_13650	2.894e-56	204.0	COG1890@1|root,arCOG04186@2157|Archaea,2XSX9@28890|Euryarchaeota,3F2MY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS1 family	rps3ae	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
DPH1_k127_12133222_4	439481.Aboo_1446	7.136e-40	156.0	COG0750@1|root,arCOG00609@2157|Archaea,2XT29@28890|Euryarchaeota,3F2WK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
DPH1_k127_12133222_2	304371.MCP_2721	2.153e-74	263.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,2NAI6@224756|Methanomicrobia	224756|Methanomicrobia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DPH1_k127_12133222_5	387631.Asulf_00018	1.247e-13	76.0	2BVY9@1|root,2N553@2157|Archaea,2Y1ZH@28890|Euryarchaeota,246I9@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_12133222_1	351160.RCIX1434	1.274e-106	360.0	COG1208@1|root,arCOG00666@2157|Archaea,2XTK6@28890|Euryarchaeota,2NBNZ@224756|Methanomicrobia	224756|Methanomicrobia	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DPH1_k127_12133222_0	880073.Calab_0773	3.487e-217	709.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
DPH1_k127_12133222_6	1234664.AMRO01000035_gene2731	2.581e-12	72.0	COG0346@1|root,COG0346@2|Bacteria,1V958@1239|Firmicutes,4HK0W@91061|Bacilli,1WGST@129337|Geobacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K11210	-	-	-	-	ko00000,ko01000	-	-	-	Glyoxalase
DPH1_k127_12133222_3	1235802.C823_03296	5.086e-42	162.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,25W7Y@186806|Eubacteriaceae	186801|Clostridia	G	KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
DPH1_k127_12180315_2	589924.Ferp_0541	2.347e-13	83.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_12180315_0	593117.TGAM_1732	3.041e-166	549.0	COG2414@1|root,arCOG00706@2157|Archaea,2Y7HF@28890|Euryarchaeota,243KE@183968|Thermococci	183968|Thermococci	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AFOR_C,AFOR_N
DPH1_k127_12180315_1	525897.Dbac_2008	4.235e-24	108.0	COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,42VM5@68525|delta/epsilon subdivisions,2WS1Q@28221|Deltaproteobacteria,2MGM4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_4,Fer4_6
DPH1_k127_12265574_0	349741.Amuc_0525	1.243e-30	139.0	COG1657@1|root,COG1657@2|Bacteria,46U97@74201|Verrucomicrobia,2ITWF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
DPH1_k127_12352755_1	673860.AciM339_0309	5.435e-53	199.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,3F2K9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DPH1_k127_12352755_2	1054217.TALC_00422	1.33e-30	131.0	COG0009@1|root,arCOG01952@2157|Archaea,2XVGC@28890|Euryarchaeota,241V4@183967|Thermoplasmata	183967|Thermoplasmata	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
DPH1_k127_12352755_0	515635.Dtur_0061	3.718e-95	323.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ccmA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DPH1_k127_1265773_7	1134445.AJJM01000002_gene2916	6.002e-32	130.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
DPH1_k127_1265773_4	456442.Mboo_2400	1.292e-68	247.0	COG0704@1|root,arCOG00318@2157|Archaea,2XUA4@28890|Euryarchaeota,2NADX@224756|Methanomicrobia	224756|Methanomicrobia	K	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
DPH1_k127_1265773_11	593750.Metfor_0543	4.355e-10	74.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota	28890|Euryarchaeota	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DPH1_k127_1265773_13	1206731.BAGB01000012_gene2711	0.000414	54.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GKQH@201174|Actinobacteria,4FVDW@85025|Nocardiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
DPH1_k127_1265773_12	1297742.A176_05825	0.0003144	55.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,RCC1_2
DPH1_k127_1265773_10	1463841.JOIR01000046_gene2031	2.848e-13	78.0	COG0671@1|root,COG0671@2|Bacteria,2I92V@201174|Actinobacteria	201174|Actinobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DPH1_k127_1265773_8	314230.DSM3645_11122	9.07e-26	112.0	COG1917@1|root,COG1917@2|Bacteria,2J1N5@203682|Planctomycetes	203682|Planctomycetes	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1265773_9	268739.Nmlp_2650	3.375e-20	109.0	COG1361@1|root,COG1470@1|root,COG3291@1|root,arCOG03612@1|root,arCOG04500@1|root,arCOG07554@1|root,arCOG02081@2157|Archaea,arCOG02089@2157|Archaea,arCOG02510@2157|Archaea,arCOG03612@2157|Archaea,arCOG04500@2157|Archaea,arCOG07554@2157|Archaea,2XWGB@28890|Euryarchaeota,23UX2@183963|Halobacteria	183963|Halobacteria	M	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1265773_3	595537.Varpa_0354	1.063e-79	287.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VPTU@28216|Betaproteobacteria,4AEAX@80864|Comamonadaceae	28216|Betaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
DPH1_k127_1265773_0	909663.KI867151_gene3063	1.605e-168	542.0	COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2MQYG@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DPH1_k127_1265773_5	368407.Memar_2279	2.005e-55	213.0	COG0704@1|root,arCOG00232@2157|Archaea,2XUZ9@28890|Euryarchaeota,2N9W2@224756|Methanomicrobia	224756|Methanomicrobia	P	Plays a role in the regulation of phosphate uptake	phoU-2	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
DPH1_k127_1265773_2	323259.Mhun_2983	6.262e-101	355.0	COG1117@1|root,arCOG00231@2157|Archaea,2XTJK@28890|Euryarchaeota,2N93D@224756|Methanomicrobia	224756|Methanomicrobia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
DPH1_k127_1265773_1	521011.Mpal_0481	5.112e-109	377.0	COG0581@1|root,arCOG00168@2157|Archaea,2Y8DS@28890|Euryarchaeota,2N9FR@224756|Methanomicrobia	224756|Methanomicrobia	P	phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DPH1_k127_1265773_6	269798.CHU_3818	1.149e-36	151.0	COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,47P5H@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
DPH1_k127_1278282_1	1236689.MMALV_13960	1.35e-126	442.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,3F2II@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
DPH1_k127_1278282_0	1236689.MMALV_09960	2.397e-141	464.0	COG0017@1|root,arCOG00406@2157|Archaea,2XTRE@28890|Euryarchaeota,3F2GB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12,6.1.1.23	ko:K09759,ko:K22503	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DPH1_k127_1278282_7	673860.AciM339_0945	2.83e-14	79.0	arCOG04079@1|root,arCOG04079@2157|Archaea,2Y184@28890|Euryarchaeota,3F3HW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1278282_6	673860.AciM339_0944	5.458e-19	93.0	arCOG00743@1|root,arCOG00743@2157|Archaea,2Y3FU@28890|Euryarchaeota,3F3AW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1278282_2	439481.Aboo_0294	7.827e-68	242.0	COG1047@1|root,arCOG00980@2157|Archaea,2XTB7@28890|Euryarchaeota,3F2P4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DPH1_k127_1278282_3	237368.SCABRO_01899	6.712e-60	228.0	COG0312@1|root,COG0312@2|Bacteria,2J2PJ@203682|Planctomycetes	203682|Planctomycetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
DPH1_k127_1278282_5	195522.BD01_1208	5.775e-20	104.0	COG1530@1|root,arCOG00321@2157|Archaea,2XU9U@28890|Euryarchaeota,24370@183968|Thermococci	183968|Thermococci	L	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DPH1_k127_1278282_4	186497.PF0933	2.105e-40	171.0	COG1199@1|root,arCOG00770@2157|Archaea,2XTH2@28890|Euryarchaeota,243PF@183968|Thermococci	183968|Thermococci	L	HELICc2	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD_2,HBB,Helicase_C_2
DPH1_k127_1304292_4	1408419.JHYG01000004_gene1277	1.078e-33	141.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VEXI@28211|Alphaproteobacteria,2JTEG@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DPH1_k127_1304292_5	673860.AciM339_0553	2.358e-31	126.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_1304292_2	1254432.SCE1572_28920	3.544e-79	271.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
DPH1_k127_1304292_0	593750.Metfor_2077	5.887e-146	469.0	COG0306@1|root,arCOG02267@2157|Archaea,2XSUU@28890|Euryarchaeota,2N9TT@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DPH1_k127_1304292_1	593750.Metfor_2077	1.016e-137	445.0	COG0306@1|root,arCOG02267@2157|Archaea,2XSUU@28890|Euryarchaeota,2N9TT@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DPH1_k127_1304292_3	368407.Memar_1039	1.749e-37	162.0	COG1392@1|root,arCOG02640@2157|Archaea	2157|Archaea	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DPH1_k127_1304292_6	768671.ThimaDRAFT_1458	1.78e-09	66.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,1RXGJ@1236|Gammaproteobacteria,1WX7E@135613|Chromatiales	135613|Chromatiales	S	von Willebrand factor, type A	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	VWA_2
DPH1_k127_1341176_8	7994.ENSAMXP00000012976	6.532e-10	73.0	2C4PM@1|root,2RT9B@2759|Eukaryota,38EBP@33154|Opisthokonta,3CQ9V@33208|Metazoa,3E6FB@33213|Bilateria,48RXX@7711|Chordata,49NCG@7742|Vertebrata,49V8X@7898|Actinopterygii	33208|Metazoa	S	Centrosomal protein 250kDa	CEP250	-	-	ko:K16464	-	-	-	-	ko00000,ko03036	-	-	-	Rootletin
DPH1_k127_1341176_4	1236689.MMALV_07840	3.321e-35	154.0	COG1901@1|root,arCOG01239@2157|Archaea,2XTSB@28890|Euryarchaeota,3F2S0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs	trmY	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.257	ko:K16317	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_2
DPH1_k127_1341176_0	439481.Aboo_0917	2.266e-157	511.0	COG0541@1|root,arCOG01228@2157|Archaea,2XTWX@28890|Euryarchaeota,3F2HD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DPH1_k127_1341176_2	1236689.MMALV_07810	1.018e-52	204.0	COG1340@1|root,arCOG01159@2157|Archaea,2XU21@28890|Euryarchaeota,3F2P7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1341176_1	673860.AciM339_0861	2.612e-129	419.0	COG0470@1|root,arCOG00469@2157|Archaea,2XTC8@28890|Euryarchaeota,3F2I9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcS	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,DNA_pol3_delta2,HTH_3,Intein_splicing,LAGLIDADG_3,Rad17,Rep_fac_C,RuvB_N
DPH1_k127_1341176_5	1122138.AQUZ01000040_gene6199	5.47e-29	128.0	COG0382@1|root,COG0382@2|Bacteria,2IJV5@201174|Actinobacteria	201174|Actinobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_1341176_9	1121945.ATXS01000001_gene2621	1.228e-07	61.0	COG1534@1|root,arCOG01346@2157|Archaea,2XZWJ@28890|Euryarchaeota,23XQI@183963|Halobacteria	183963|Halobacteria	J	RNA-binding protein containing KH domain, possibly ribosomal protein	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
DPH1_k127_1341176_7	304371.MCP_0304	1.608e-18	97.0	COG2023@1|root,arCOG04345@2157|Archaea,2XYX0@28890|Euryarchaeota,2NA13@224756|Methanomicrobia	224756|Methanomicrobia	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	-	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
DPH1_k127_1341176_3	273068.TTE0824	2.022e-40	174.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,42FS7@68295|Thermoanaerobacterales	186801|Clostridia	M	Serine protease with a broad substrate specificity	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
DPH1_k127_1341176_6	96561.Dole_0842	2.638e-20	108.0	COG3209@1|root,COG3386@1|root,COG3209@2|Bacteria,COG3386@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2MN6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
DPH1_k127_1344332_2	1128421.JAGA01000002_gene1152	5.269e-09	61.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2NR6B@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_1344332_1	756883.Halar_2971	2.673e-27	124.0	arCOG06011@1|root,arCOG06011@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
DPH1_k127_1344332_0	247490.KSU1_D0991	5.601e-62	227.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2IXEZ@203682|Planctomycetes	203682|Planctomycetes	P	COG0491 Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DPH1_k127_1356159_1	1385935.N836_09970	2.066e-10	65.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	MA20_21040	-	1.1.1.193,1.1.1.302,3.5.4.26	ko:K00082,ko:K11752,ko:K14654	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459,R09375,R09376	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
DPH1_k127_1356159_0	693661.Arcve_0149	3.811e-39	152.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_1386369_0	697303.Thewi_1978	2.323e-115	391.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
DPH1_k127_1386369_1	673860.AciM339_0043	1.569e-104	349.0	COG1899@1|root,arCOG04142@2157|Archaea,2XSTD@28890|Euryarchaeota,3F2F3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DPH1_k127_1386640_1	237368.SCABRO_03600	1.559e-10	68.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1386640_0	1054217.TALC_00431	9.099e-67	241.0	COG1084@1|root,arCOG00352@2157|Archaea,2XU5R@28890|Euryarchaeota,241NE@183967|Thermoplasmata	183967|Thermoplasmata	S	Nucleolar GTP-binding protein 1 (NOG1)	-	-	-	ko:K06943	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	MMR_HSR1,NOG1
DPH1_k127_1397403_2	1121403.AUCV01000001_gene847	1.2e-09	70.0	COG1800@1|root,COG1800@2|Bacteria,1Q1K7@1224|Proteobacteria,42YDF@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1397403_0	273116.14324238	6.245e-150	487.0	COG0160@1|root,arCOG00915@2157|Archaea,2Y83J@28890|Euryarchaeota,2421R@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DPH1_k127_1397403_1	1111479.AXAR01000004_gene2194	2.743e-83	292.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,27837@186823|Alicyclobacillaceae	91061|Bacilli	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU39370	Amidohydro_1,Amidohydro_3
DPH1_k127_1412713_1	1054217.TALC_01451	8.704e-52	194.0	COG0061@1|root,COG0483@1|root,arCOG01348@2157|Archaea,arCOG01349@2157|Archaea,2XTP6@28890|Euryarchaeota,241Q7@183967|Thermoplasmata	183967|Thermoplasmata	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DPH1_k127_1412713_4	673860.AciM339_0974	4.275e-29	121.0	COG1310@1|root,arCOG01139@2157|Archaea,2XWKU@28890|Euryarchaeota,3F2SY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
DPH1_k127_1412713_2	545697.HMPREF0216_02608	4.996e-40	162.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
DPH1_k127_1412713_6	498848.TaqDRAFT_3998	6.722e-12	76.0	COG1082@1|root,COG1082@2|Bacteria,1WI0M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DPH1_k127_1412713_0	1191523.MROS_1683	3.241e-71	253.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DPH1_k127_1412713_5	694429.Pyrfu_1149	3.906e-16	94.0	COG1470@1|root,COG2319@1|root,arCOG03264@1|root,arCOG02087@2157|Archaea,arCOG02491@2157|Archaea,arCOG03264@2157|Archaea,2XRJZ@28889|Crenarchaeota	28889|Crenarchaeota	S	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1412713_8	247490.KSU1_C1104	2.702e-08	68.0	COG0823@1|root,COG3291@1|root,COG3828@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2J1GZ@203682|Planctomycetes	203682|Planctomycetes	U	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_1412713_7	981369.JQMJ01000004_gene1018	4.372e-10	74.0	COG3291@1|root,COG3291@2|Bacteria,2HHTF@201174|Actinobacteria,2NHQJ@228398|Streptacidiphilus	201174|Actinobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Phosphoesterase,fn3
DPH1_k127_1412713_9	246200.SPO0571	0.0002837	53.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_1412713_3	255470.cbdbA785	3.699e-36	143.0	COG1233@1|root,COG1233@2|Bacteria,2G5ZA@200795|Chloroflexi,34D93@301297|Dehalococcoidia	301297|Dehalococcoidia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DPH1_k127_1427744_0	439481.Aboo_0781	2.106e-92	316.0	COG1469@1|root,arCOG04301@2157|Archaea,2XT11@28890|Euryarchaeota,3F2JX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin	mptA	GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682	3.5.4.39	ko:K17488	ko00790,map00790	-	R10348	RC02504,RC03131	ko00000,ko00001,ko01000	-	-	-	GCHY-1
DPH1_k127_1427744_1	386456.JQKN01000002_gene2802	1.478e-12	81.0	COG1371@1|root,arCOG04055@2157|Archaea,2XXRX@28890|Euryarchaeota,23P74@183925|Methanobacteria	183925|Methanobacteria	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
DPH1_k127_1429458_2	118163.Ple7327_2177	1.178e-08	65.0	COG3809@1|root,COG3809@2|Bacteria,1G6XN@1117|Cyanobacteria,3VK8D@52604|Pleurocapsales	1117|Cyanobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
DPH1_k127_1429458_1	765420.OSCT_2228	8.983e-76	280.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,YARHG,zinc_ribbon_2
DPH1_k127_1429458_0	449447.MAE_12400	2.976e-103	351.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	bhp	-	-	ko:K13735,ko:K20276,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	B_lectin,Big_3_2,Big_5,Calx-beta,DUF4347,HemolysinCabind
DPH1_k127_1496122_3	388467.A19Y_2739	5.237e-09	67.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	JAB,Prok-JAB
DPH1_k127_1496122_5	1089545.KB913037_gene7942	2.093e-05	53.0	COG5078@1|root,COG5078@2|Bacteria,2IJY9@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Ubiquitin-conjugating	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1496122_4	439481.Aboo_0924	2.198e-08	70.0	COG0419@1|root,COG1361@1|root,arCOG00368@2157|Archaea,arCOG02080@2157|Archaea	2157|Archaea	M	Peptidase family C25	-	-	3.1.3.16	ko:K03546,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009,ko03400	-	-	-	CARDB,MMPL
DPH1_k127_1496122_2	673860.AciM339_0080	3.225e-09	73.0	COG1196@1|root,COG1361@1|root,arCOG05232@1|root,arCOG06883@1|root,arCOG00371@2157|Archaea,arCOG04400@2157|Archaea,arCOG05232@2157|Archaea,arCOG06883@2157|Archaea	2157|Archaea	S	Tubulin like	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF2334,DZR,Tubulin_2
DPH1_k127_1496122_0	1278073.MYSTI_05406	3.783e-48	184.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
DPH1_k127_1496122_1	368407.Memar_1422	1.262e-43	166.0	COG2897@1|root,arCOG02019@2157|Archaea,2Y76U@28890|Euryarchaeota,2NBE7@224756|Methanomicrobia	224756|Methanomicrobia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DPH1_k127_1498855_1	246969.TAM4_1004	5.56e-22	100.0	COG2412@1|root,arCOG04051@2157|Archaea,2XYQK@28890|Euryarchaeota,244B2@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
DPH1_k127_1498855_0	439481.Aboo_0204	2.776e-73	256.0	COG0462@1|root,arCOG00067@2157|Archaea,2XTA8@28890|Euryarchaeota,3F2FN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
DPH1_k127_1498855_2	1094980.Mpsy_2536	1.737e-15	77.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota,2NA39@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
DPH1_k127_1498855_3	401526.TcarDRAFT_0379	1.076e-05	58.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4H4WN@909932|Negativicutes	909932|Negativicutes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
DPH1_k127_1500937_1	1500894.JQNN01000001_gene822	7.743e-19	102.0	COG2203@1|root,COG3292@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMUZ@28216|Betaproteobacteria,475JP@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Reg_prop,Y_Y_Y
DPH1_k127_1500937_0	237368.SCABRO_00239	3.254e-35	148.0	COG1657@1|root,COG1657@2|Bacteria,2IXAS@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
DPH1_k127_1502646_0	1280390.CBQR020000063_gene1331	4.629e-53	201.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,26R4Y@186822|Paenibacillaceae	91061|Bacilli	C	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
DPH1_k127_1502646_1	349966.DJ58_3615	2.025e-08	62.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,1RNEJ@1236|Gammaproteobacteria,41EFF@629|Yersinia	1236|Gammaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0071704	4.1.3.25,4.1.3.34	ko:K01644,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	iSFxv_1172.SFxv_0589	HpcH_HpaI
DPH1_k127_1511845_0	192952.MM_2611	4.55e-174	557.0	COG2509@1|root,arCOG02231@2157|Archaea,2XTVH@28890|Euryarchaeota,2N9BS@224756|Methanomicrobia	224756|Methanomicrobia	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2
DPH1_k127_1511845_1	439481.Aboo_1029	8.281e-124	408.0	COG1373@1|root,arCOG03167@2157|Archaea,2Y3YG@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DPH1_k127_1511845_2	439481.Aboo_0043	5.515e-52	198.0	COG0565@1|root,arCOG01018@2157|Archaea,2XUIY@28890|Euryarchaeota,3F2NC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	TIGRFAM RNA methyltransferase, TrmH family, group 1	trmH	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
DPH1_k127_1511845_3	443143.GM18_3969	6.005e-37	143.0	COG1917@1|root,COG1917@2|Bacteria,1N13F@1224|Proteobacteria,43BFG@68525|delta/epsilon subdivisions,2X6TV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DPH1_k127_1511845_4	1094508.Tsac_0824	5.461e-32	134.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia,42GA1@68295|Thermoanaerobacterales	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	mtnX	-	-	-	-	-	-	-	-	-	-	-	HAD,Put_Phosphatase
DPH1_k127_1513211_0	10224.XP_006823013.1	1.933e-26	122.0	KOG0613@1|root,KOG0613@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria	33208|Metazoa	T	myosin light chain kinase activity	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,fn3
DPH1_k127_1513211_1	102129.Lepto7375DRAFT_0842	3.719e-20	107.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,1G4UG@1117|Cyanobacteria,1HH6U@1150|Oscillatoriales	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
DPH1_k127_1513211_2	99598.Cal7507_2710	2.147e-06	62.0	COG2885@1|root,COG2885@2|Bacteria,1G2YF@1117|Cyanobacteria,1HMYH@1161|Nostocales	1117|Cyanobacteria	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	OmpA
DPH1_k127_1522713_0	485915.Dret_1495	1.608e-102	347.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,42PSQ@68525|delta/epsilon subdivisions,2WKDY@28221|Deltaproteobacteria,2M8IA@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
DPH1_k127_1522713_1	404380.Gbem_3571	2.813e-56	205.0	COG4832@1|root,COG4832@2|Bacteria,1RBGY@1224|Proteobacteria	1224|Proteobacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
DPH1_k127_1522713_2	309799.DICTH_1716	1.863e-53	192.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
DPH1_k127_1529764_0	497965.Cyan7822_3550	2.073e-221	694.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
DPH1_k127_1529764_1	673860.AciM339_0737	2.757e-166	548.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,3F2GC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DPH1_k127_1529764_3	1123248.KB893315_gene2993	1.515e-16	91.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,4NGX5@976|Bacteroidetes,1IRAD@117747|Sphingobacteriia	976|Bacteroidetes	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
DPH1_k127_1529764_2	518766.Rmar_1279	5.348e-29	124.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1FK7U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	FeoA	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DPH1_k127_1529764_4	1304866.K413DRAFT_5077	4.735e-12	79.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,36DEB@31979|Clostridiaceae	186801|Clostridia	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DPH1_k127_1539682_2	926569.ANT_07500	2.61e-08	66.0	COG1470@1|root,COG2374@1|root,COG1470@2|Bacteria,COG2374@2|Bacteria,2G82K@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Exo_endo_phos,LTD
DPH1_k127_1539682_1	456442.Mboo_0238	1.404e-13	72.0	COG1552@1|root,arCOG04049@2157|Archaea,2Y177@28890|Euryarchaeota,2NB9F@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eL40 family	rpl40e	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L40e
DPH1_k127_1539682_0	644282.Deba_2986	1.076e-88	305.0	COG0095@1|root,COG0095@2|Bacteria,1RDZE@1224|Proteobacteria	1224|Proteobacteria	H	PFAM biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
DPH1_k127_1574428_0	1120953.AUBH01000004_gene2970	4.817e-05	55.0	COG1361@1|root,COG3637@1|root,COG5295@1|root,COG1361@2|Bacteria,COG3637@2|Bacteria,COG5295@2|Bacteria,1QVUF@1224|Proteobacteria,1T2J7@1236|Gammaproteobacteria,46DCC@72275|Alteromonadaceae	1236|Gammaproteobacteria	MUW	this gene contains a nucleotide ambiguity which may be the result of a sequencing error	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,OmpA
DPH1_k127_1591274_0	1236689.MMALV_07510	2.034e-140	456.0	COG1602@1|root,arCOG04269@2157|Archaea,2XTEQ@28890|Euryarchaeota,3F34R@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Archaeal Nre, N-terminal	nreA	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
DPH1_k127_1591274_4	1041930.Mtc_1304	2.383e-61	236.0	COG1533@1|root,arCOG01290@2157|Archaea,2XY2A@28890|Euryarchaeota,2N9Z2@224756|Methanomicrobia	224756|Methanomicrobia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DPH1_k127_1591274_7	1463934.JOCF01000035_gene2420	0.0001526	55.0	COG4409@1|root,COG4409@2|Bacteria,2ID1A@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1591274_3	264462.Bd0328	2.73e-75	288.0	COG0457@1|root,COG0457@2|Bacteria,1QY1G@1224|Proteobacteria,43C8T@68525|delta/epsilon subdivisions,2MUD4@213481|Bdellovibrionales,2X7J5@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DPH1_k127_1591274_5	1324957.K933_16552	4.108e-30	140.0	COG3291@1|root,COG3979@1|root,arCOG02499@1|root,arCOG07560@1|root,arCOG02499@2157|Archaea,arCOG02508@2157|Archaea,arCOG07560@2157|Archaea,arCOG07581@2157|Archaea,2Y80Y@28890|Euryarchaeota,24124@183963|Halobacteria	183963|Halobacteria	G	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_1591274_2	1459636.NTE_02180	2.499e-112	369.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
DPH1_k127_1591274_1	706587.Desti_0486	6.386e-123	405.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42SJQ@68525|delta/epsilon subdivisions,2WPH7@28221|Deltaproteobacteria,2MRF5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
DPH1_k127_1591274_6	509191.AEDB02000033_gene5135	9.592e-30	124.0	2DMZP@1|root,32UMQ@2|Bacteria,1VHU7@1239|Firmicutes,24QKJ@186801|Clostridia,3WKPR@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
DPH1_k127_1594657_2	573370.DMR_37530	1.644e-20	95.0	COG0648@1|root,COG0648@2|Bacteria,1N9ZF@1224|Proteobacteria,43EYJ@68525|delta/epsilon subdivisions,2WV80@28221|Deltaproteobacteria,2MANC@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
DPH1_k127_1594657_0	1121430.JMLG01000009_gene429	1.659e-75	271.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
DPH1_k127_1594657_4	67352.JODS01000017_gene2929	1.157e-07	66.0	COG1572@1|root,COG1572@2|Bacteria,2H1Z9@201174|Actinobacteria	201174|Actinobacteria	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C
DPH1_k127_1594657_1	1121481.AUAS01000003_gene3739	4.495e-27	130.0	COG2931@1|root,COG5184@1|root,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
DPH1_k127_1594657_3	526225.Gobs_2507	2.012e-16	87.0	COG2866@1|root,COG2866@2|Bacteria,2GN49@201174|Actinobacteria	2|Bacteria	E	carboxypeptidase	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6,fn3
DPH1_k127_1611618_0	351160.RCIX132	2.524e-123	400.0	arCOG01917@1|root,arCOG01917@2157|Archaea,2XYA0@28890|Euryarchaeota	28890|Euryarchaeota	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
DPH1_k127_1611618_1	304371.MCP_2737	7.118e-34	139.0	arCOG05710@1|root,arCOG05710@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1614297_1	1445613.JALM01000019_gene5767	5.549e-25	114.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
DPH1_k127_1614297_2	1894.JOER01000006_gene913	1.56e-18	99.0	COG1670@1|root,COG1670@2|Bacteria,2INDG@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_3
DPH1_k127_1614297_0	292459.STH1757	2.282e-142	471.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DPH1_k127_1671593_0	1449050.JNLE01000003_gene1690	2.808e-12	82.0	COG1572@1|root,COG5492@1|root,COG1572@2|Bacteria,COG5492@2|Bacteria,1UVYI@1239|Firmicutes,250YY@186801|Clostridia,36Q2E@31979|Clostridiaceae	186801|Clostridia	N	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
DPH1_k127_1706274_2	1236689.MMALV_07250	1.878e-07	60.0	arCOG02981@1|root,arCOG02981@2157|Archaea,2Y4VF@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1706274_0	880073.Calab_3690	1.835e-13	78.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
DPH1_k127_1706274_1	1094980.Mpsy_1105	1.523e-11	70.0	arCOG01814@1|root,arCOG01814@2157|Archaea,2XT74@28890|Euryarchaeota,2N90N@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1734891_2	237368.SCABRO_01236	1.738e-10	76.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DPH1_k127_1734891_1	118173.KB235914_gene1471	5.289e-35	156.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1HAPX@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
DPH1_k127_1734891_0	316274.Haur_4661	9.581e-83	287.0	COG0477@1|root,COG2814@2|Bacteria,2G5ZW@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_1782776_3	232721.Ajs_1872	8.316e-09	59.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,Pribosyltran,Proteasom_PSMB,zinc_ribbon_2
DPH1_k127_1782776_1	304371.MCP_2735	4.897e-73	254.0	arCOG03776@1|root,arCOG03776@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TF_Zn_Ribbon
DPH1_k127_1782776_0	351160.RCIX130	9.827e-91	310.0	arCOG03776@1|root,arCOG03776@2157|Archaea,2Y520@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1782776_2	351160.RCIX128	5.642e-25	113.0	arCOG07446@1|root,arCOG07446@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_1867595_0	743718.Isova_1197	1.585e-20	103.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4F47E@85017|Promicromonosporaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DPH1_k127_187190_1	269799.Gmet_1209	2.564e-33	145.0	COG2931@1|root,COG2931@2|Bacteria,1QVQT@1224|Proteobacteria	1224|Proteobacteria	Q	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
DPH1_k127_187190_2	679926.Mpet_0355	2.941e-28	121.0	COG0640@1|root,arCOG01680@2157|Archaea,2Y05Q@28890|Euryarchaeota,2NA1B@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
DPH1_k127_187190_0	368407.Memar_0016	1.344e-109	365.0	COG0701@1|root,arCOG02712@2157|Archaea,2XVVT@28890|Euryarchaeota,2N9A7@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
DPH1_k127_1948793_1	1121957.ATVL01000006_gene2738	0.0001136	52.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DPH1_k127_1948793_0	1042877.GQS_08245	2.135e-08	63.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,2440W@183968|Thermococci	183968|Thermococci	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_2000447_0	667014.Thein_1716	5.707e-33	138.0	COG1418@1|root,COG1418@2|Bacteria,2GIAK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
DPH1_k127_2000447_1	1220534.B655_0025	2.355e-06	56.0	COG1531@1|root,arCOG01302@2157|Archaea	2157|Archaea	S	Belongs to the UPF0248 family	-	-	-	ko:K09715	-	-	-	-	ko00000	-	-	-	DUF504
DPH1_k127_2006116_0	673860.AciM339_0510	3.531e-113	374.0	COG0371@1|root,arCOG00982@2157|Archaea,2XT0F@28890|Euryarchaeota,3F2IT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
DPH1_k127_2006116_1	268739.Nmlp_2802	3.943e-15	83.0	COG1967@1|root,arCOG02177@2157|Archaea,2XT8V@28890|Euryarchaeota,23SFQ@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF63
DPH1_k127_2015235_0	1499967.BAYZ01000013_gene6439	4.59e-239	755.0	COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,GlcNAc_2-epim,Thioredox_DsbH
DPH1_k127_2015235_7	373903.Hore_15950	1.75e-55	200.0	COG0778@1|root,COG0778@2|Bacteria,1V49Q@1239|Firmicutes,24IH8@186801|Clostridia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_2015235_6	648996.Theam_0591	1.397e-58	207.0	COG1225@1|root,COG1225@2|Bacteria,2G42T@200783|Aquificae	200783|Aquificae	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DPH1_k127_2015235_8	69014.TK0815	2.158e-54	194.0	COG1225@1|root,arCOG00310@2157|Archaea,2XY0E@28890|Euryarchaeota,2440M@183968|Thermococci	183968|Thermococci	O	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DPH1_k127_2015235_3	1220534.B655_0402	7.331e-120	398.0	COG1013@1|root,arCOG01599@2157|Archaea,2XTW2@28890|Euryarchaeota,23PWY@183925|Methanobacteria	183925|Methanobacteria	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
DPH1_k127_2015235_1	381764.Fnod_0055	1.985e-201	644.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GC9M@200918|Thermotogae	200918|Thermotogae	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	POR,POR_N
DPH1_k127_2015235_9	673860.AciM339_0132	2.289e-40	156.0	COG1633@1|root,arCOG01103@2157|Archaea,2Y69T@28890|Euryarchaeota,3F3G4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DPH1_k127_2015235_4	1379281.AVAG01000023_gene1915	9.577e-73	251.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2M9B4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DPH1_k127_2015235_12	644281.MFS40622_1437	4.153e-17	81.0	COG1773@1|root,arCOG05047@2157|Archaea,2XZY1@28890|Euryarchaeota,23R7T@183939|Methanococci	183939|Methanococci	C	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2015235_2	1121422.AUMW01000028_gene3417	1.275e-177	563.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,2619Q@186807|Peptococcaceae	186801|Clostridia	C	PFAM Flavodoxin	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
DPH1_k127_2015235_11	373903.Hore_22490	3.796e-22	107.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,3WC7H@53433|Halanaerobiales	186801|Clostridia	C	PFAM Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
DPH1_k127_2015235_10	1408439.JHXW01000009_gene390	5.174e-26	115.0	COG0735@1|root,COG0735@2|Bacteria,37ADT@32066|Fusobacteria	32066|Fusobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DPH1_k127_2015235_5	290397.Adeh_1286	3.794e-65	229.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DPH1_k127_2015235_13	443143.GM18_1006	1.886e-11	76.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2017947_1	446465.Bfae_02880	9.393e-24	118.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FDQP@85020|Dermabacteraceae	201174|Actinobacteria	S	Laminin G domain	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_2017947_2	1121920.AUAU01000039_gene1425	1.899e-15	91.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.3.5,3.2.1.14	ko:K01081,ko:K01183,ko:K20276	ko00230,ko00240,ko00520,ko00760,ko01100,ko01110,ko02024,map00230,map00240,map00520,map00760,map01100,map01110,map02024	-	R00183,R00511,R00963,R01126,R01206,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02334,R02719,R03346	RC00017,RC00467	ko00000,ko00001,ko01000	-	GH18	-	F5_F8_type_C,Melibiase_2,NPCBM_assoc,PKD,PPC,Trypsin_2,VPEP
DPH1_k127_2017947_0	1234364.AMSF01000053_gene1325	3.447e-35	135.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales	135614|Xanthomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DPH1_k127_2026276_0	155864.EDL933_0566	0.0001077	55.0	COG2373@1|root,COG2911@1|root,COG2931@1|root,COG3291@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	von willebrand factor, type A	lapA	-	-	ko:K12549	-	-	-	-	ko00000	-	-	-	Big_3_2,Cadherin_3,Calx-beta,HemolysinCabind,VCBS,VWA,VWA_2
DPH1_k127_2047487_0	868131.MSWAN_1557	2.967e-45	181.0	COG0842@1|root,arCOG01463@2157|Archaea,2Y34U@28890|Euryarchaeota,23PDD@183925|Methanobacteria	183925|Methanobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DPH1_k127_2047487_2	868131.MSWAN_1557	1.686e-40	169.0	COG0842@1|root,arCOG01463@2157|Archaea,2Y34U@28890|Euryarchaeota,23PDD@183925|Methanobacteria	183925|Methanobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DPH1_k127_2047487_1	420247.Msm_1483	1.433e-43	163.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,23PFF@183925|Methanobacteria	183925|Methanobacteria	E	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_2059014_2	243231.GSU2914	3.254e-20	108.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,43C5A@68525|delta/epsilon subdivisions,2WNBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2059014_1	453591.Igni_0850	4.626e-36	144.0	COG1514@1|root,arCOG01736@2157|Archaea,2XQM6@28889|Crenarchaeota	28889|Crenarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DPH1_k127_2059014_0	673860.AciM339_1098	4.184e-112	395.0	COG0087@1|root,arCOG04070@2157|Archaea,2XT9B@28890|Euryarchaeota,3F2H1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DPH1_k127_2082636_1	192952.MM_0300	2.203e-119	394.0	COG0449@1|root,arCOG00057@2157|Archaea,2XTC0@28890|Euryarchaeota,2N92X@224756|Methanomicrobia	224756|Methanomicrobia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DPH1_k127_2082636_10	1150474.JQJI01000040_gene1934	0.0001109	53.0	COG3428@1|root,COG3428@2|Bacteria,2GDHH@200918|Thermotogae	200918|Thermotogae	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
DPH1_k127_2082636_9	401053.AciPR4_2697	1.64e-08	68.0	COG0823@1|root,COG0823@2|Bacteria,3Y4FU@57723|Acidobacteria,2JJ6C@204432|Acidobacteriia	204432|Acidobacteriia	U	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DPH1_k127_2082636_7	5888.CAK76467	3.039e-20	93.0	COG1644@1|root,KOG3497@2759|Eukaryota,3ZF02@5878|Ciliophora	2759|Eukaryota	K	RNA polymerases N / 8 kDa subunit	POLR2L	GO:0000375,GO:0000377,GO:0000398,GO:0000418,GO:0000419,GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0005666,GO:0005730,GO:0005736,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006351,GO:0006352,GO:0006353,GO:0006354,GO:0006355,GO:0006356,GO:0006360,GO:0006361,GO:0006363,GO:0006366,GO:0006367,GO:0006368,GO:0006370,GO:0006383,GO:0006396,GO:0006397,GO:0006399,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0008150,GO:0008152,GO:0008270,GO:0008380,GO:0008543,GO:0009058,GO:0009059,GO:0009301,GO:0009304,GO:0009452,GO:0009719,GO:0009889,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0016070,GO:0016071,GO:0016073,GO:0016591,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0030880,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0033554,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0036260,GO:0040029,GO:0042221,GO:0042795,GO:0042797,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0045815,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0055029,GO:0060147,GO:0060255,GO:0060964,GO:0060966,GO:0060968,GO:0061695,GO:0065007,GO:0070013,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0080090,GO:0090304,GO:0097659,GO:0097747,GO:0098781,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141	3.6.4.12	ko:K02912,ko:K03007,ko:K11313,ko:K15271	ko00230,ko00240,ko01100,ko03010,ko03020,ko04623,ko05016,ko05169,ko05202,map00230,map00240,map01100,map03010,map03020,map04623,map05016,map05169,map05202	M00177,M00179,M00180,M00181,M00182	R00435,R00441,R00442,R00443	RC02795	br01610,br01611,ko00000,ko00001,ko00002,ko01000,ko03011,ko03021,ko03036,ko03400	-	-	-	RNA_pol_N
DPH1_k127_2082636_4	589924.Ferp_1963	3.939e-46	169.0	COG0088@1|root,arCOG04243@2157|Archaea,2XWK0@28890|Euryarchaeota,2471N@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the universal ribosomal protein uS9 family	rps9	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DPH1_k127_2082636_5	673860.AciM339_1029	5.524e-39	149.0	COG0102@1|root,arCOG04242@2157|Archaea,2XWN6@28890|Euryarchaeota,3F2SC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DPH1_k127_2082636_6	439481.Aboo_1474	6.59e-31	125.0	COG1727@1|root,arCOG00780@2157|Archaea,2XZ6R@28890|Euryarchaeota,3F2U4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18,Ribosomal_L27A
DPH1_k127_2082636_3	926550.CLDAP_28350	7.089e-68	252.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
DPH1_k127_2082636_0	676032.FN3523_0346	6.14e-128	421.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,1RQVD@1236|Gammaproteobacteria,461HS@72273|Thiotrichales	72273|Thiotrichales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
DPH1_k127_2082636_8	1121921.KB898706_gene3381	1.339e-10	73.0	COG3291@1|root,COG3325@1|root,COG3979@1|root,COG3291@2|Bacteria,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,2PMUU@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Glyco_18	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,Glyco_hydro_18,PKD,fn3
DPH1_k127_2082636_2	266117.Rxyl_0594	4.496e-77	269.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CPWR@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
DPH1_k127_20828_0	314266.SKA58_07138	1.953e-05	56.0	COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,2U6PC@28211|Alphaproteobacteria,2K0Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DPH1_k127_2083740_0	1227453.C444_19682	0.0001496	55.0	arCOG03610@1|root,arCOG05978@1|root,arCOG03610@2157|Archaea,arCOG05978@2157|Archaea,2Y1SB@28890|Euryarchaeota,23YTJ@183963|Halobacteria	183963|Halobacteria	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2110213_4	1123054.KB907711_gene361	1.832e-14	76.0	COG1404@1|root,COG3266@1|root,COG1404@2|Bacteria,COG3266@2|Bacteria,1RC5K@1224|Proteobacteria,1S3I9@1236|Gammaproteobacteria,1WXY7@135613|Chromatiales	135613|Chromatiales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DPH1_k127_2110213_1	215803.DB30_4860	8.272e-37	149.0	29Z39@1|root,30M0T@2|Bacteria,1Q3Q8@1224|Proteobacteria,439HD@68525|delta/epsilon subdivisions,2X4TN@28221|Deltaproteobacteria,2YZK3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2110213_2	673860.AciM339_1461	6.758e-31	131.0	COG1916@1|root,arCOG02142@2157|Archaea,2Y6XP@28890|Euryarchaeota,3F2SA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	TraB family	-	-	-	-	-	-	-	-	-	-	-	-	TraB
DPH1_k127_2110213_3	1123054.KB907711_gene361	1.217e-19	96.0	COG1404@1|root,COG3266@1|root,COG1404@2|Bacteria,COG3266@2|Bacteria,1RC5K@1224|Proteobacteria,1S3I9@1236|Gammaproteobacteria,1WXY7@135613|Chromatiales	135613|Chromatiales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DPH1_k127_2110213_0	1236689.MMALV_00640	7.116e-116	384.0	COG1031@1|root,arCOG01359@2157|Archaea,2XSVQ@28890|Euryarchaeota,3F2GV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH,HHH_3,Radical_SAM
DPH1_k127_2110834_0	309801.trd_0486	7.678e-30	138.0	COG0599@1|root,COG0599@2|Bacteria,2GA0S@200795|Chloroflexi,27YG5@189775|Thermomicrobia	189775|Thermomicrobia	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DPH1_k127_2110834_2	4565.Traes_2AL_CB8D989DF.1	0.0006746	53.0	COG0515@1|root,2QRP1@2759|Eukaryota,37RK9@33090|Viridiplantae,3GB4W@35493|Streptophyta,3KQHR@4447|Liliopsida,3IFM2@38820|Poales	35493|Streptophyta	T	Inactive receptor kinase	-	GO:0002831,GO:0002832,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0008150,GO:0009507,GO:0009536,GO:0016020,GO:0031347,GO:0031348,GO:0032101,GO:0032102,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043900,GO:0043901,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048583,GO:0048585,GO:0050789,GO:0065007,GO:0071944,GO:0080134,GO:1900150,GO:1900424,GO:1900425	-	-	-	-	-	-	-	-	-	-	LRRNT_2,LRR_1,LRR_6,LRR_8,Pkinase,Pkinase_Tyr
DPH1_k127_2110834_1	1347368.HG964403_gene4490	1.952e-25	124.0	COG4632@1|root,COG5492@1|root,COG4632@2|Bacteria,COG5492@2|Bacteria,1V706@1239|Firmicutes,4IQJJ@91061|Bacilli	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_2110919_1	444157.Tneu_1126	1.372e-82	293.0	COG0063@1|root,arCOG00018@2157|Archaea,2XPXN@28889|Crenarchaeota	28889|Crenarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DPH1_k127_2110919_2	670487.Ocepr_0305	8.791e-17	93.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DPH1_k127_2110919_0	269799.Gmet_1761	3.91e-109	380.0	COG0191@1|root,COG0191@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,OprB,SLH
DPH1_k127_216124_0	383372.Rcas_3603	3.856e-36	144.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
DPH1_k127_2165556_4	673860.AciM339_1269	1.018e-33	136.0	COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,3F2F0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DNA polymerase type-B family	polB1	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1,Intein_splicing
DPH1_k127_2165556_2	351160.LRC299	1.403e-68	250.0	COG1467@1|root,arCOG04110@2157|Archaea,2XUZF@28890|Euryarchaeota,2N95F@224756|Methanomicrobia	224756|Methanomicrobia	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	-	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
DPH1_k127_2165556_0	1041930.Mtc_2135	1.707e-75	268.0	COG2219@1|root,arCOG03013@2157|Archaea,2XTDT@28890|Euryarchaeota,2N9HY@224756|Methanomicrobia	224756|Methanomicrobia	L	Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priL	-	-	ko:K18882	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_lrg
DPH1_k127_2165556_1	1236689.MMALV_01790	3.55e-72	250.0	COG0592@1|root,arCOG00488@2157|Archaea,2XT8B@28890|Euryarchaeota,3F2MA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
DPH1_k127_2165556_5	644281.MFS40622_0780	1.202e-29	121.0	COG1594@1|root,arCOG00579@2157|Archaea,2XY3E@28890|Euryarchaeota,23R2W@183939|Methanococci	183939|Methanococci	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	RNA_POL_M_15KD,TFIIS_C
DPH1_k127_2165556_3	573064.Mefer_1234	1.262e-46	172.0	COG0184@1|root,arCOG04185@2157|Archaea,2XWKV@28890|Euryarchaeota,23QST@183939|Methanococci	183939|Methanococci	J	ribosomal protein S15	rps15	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
DPH1_k127_2165556_6	1236689.MMALV_15590	1.518e-15	85.0	COG0608@1|root,arCOG00427@2157|Archaea,2XW5A@28890|Euryarchaeota,3F2M1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHH,DHHA1
DPH1_k127_2174768_4	195103.CPF_1123	2.007e-15	91.0	COG0841@1|root,COG1404@1|root,COG0841@2|Bacteria,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,25EBB@186801|Clostridia,36DW5@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_3_2,Cadherin-like,Inhibitor_I9,PA,Peptidase_S8,fn3_5
DPH1_k127_2174768_3	1249627.D779_3142	2.077e-21	112.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,LysM,fn3
DPH1_k127_2174768_6	1203556.HMPREF1478_01281	1.062e-13	83.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4D47Y@85005|Actinomycetales	201174|Actinobacteria	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_2174768_2	348780.NP_0100A	3.862e-62	222.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,23T7A@183963|Halobacteria	183963|Halobacteria	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_2174768_7	1463900.JOIX01000046_gene6851	5.355e-09	68.0	COG3127@1|root,COG3127@2|Bacteria,2GKK6@201174|Actinobacteria	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DPH1_k127_2174768_1	673860.AciM339_1253	2.76e-63	235.0	COG1355@1|root,arCOG01728@2157|Archaea,2XVYU@28890|Euryarchaeota,3F2NT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Belongs to the MEMO1 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
DPH1_k127_2174768_0	1054217.TALC_00169	2.144e-80	272.0	COG0052@1|root,arCOG04245@2157|Archaea,2XTHM@28890|Euryarchaeota,241MQ@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DPH1_k127_2174768_5	673860.AciM339_0075	3.62e-15	76.0	COG1758@1|root,arCOG01268@2157|Archaea,2XZSW@28890|Euryarchaeota,3F2TZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	2.7.7.6	ko:K03055	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb6
DPH1_k127_2175556_0	326427.Cagg_2205	3.235e-08	66.0	COG2823@1|root,COG2823@2|Bacteria,2GA85@200795|Chloroflexi,376AG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2194710_0	1151117.AJLF01000001_gene1243	8.577e-188	605.0	COG0441@1|root,arCOG00401@2157|Archaea,2XTFI@28890|Euryarchaeota,242P8@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
DPH1_k127_2214145_0	1070774.J07HN4v3_00095	1.476e-06	60.0	arCOG07655@1|root,arCOG07655@2157|Archaea,2Y71F@28890|Euryarchaeota,23UID@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2229645_1	439481.Aboo_0588	1.258e-22	108.0	COG1340@1|root,arCOG01159@2157|Archaea,2Y70M@28890|Euryarchaeota,3F338@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2229645_0	273116.14324294	2.282e-67	251.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,241PN@183967|Thermoplasmata	183967|Thermoplasmata	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DPH1_k127_2234290_2	673860.AciM339_0749	8.971e-66	244.0	COG0517@1|root,COG0750@1|root,arCOG00607@2157|Archaea,arCOG04064@2157|Archaea,2XSZP@28890|Euryarchaeota,3F2KK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
DPH1_k127_2234290_5	1236689.MMALV_13580	1.679e-19	90.0	COG1958@1|root,arCOG00998@2157|Archaea,2XZTF@28890|Euryarchaeota,3F2SB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	snRNP Sm proteins	lsm	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
DPH1_k127_2234290_6	633148.Tagg_1247	8.07e-16	79.0	COG2126@1|root,arCOG04126@2157|Archaea,2XR4H@28889|Crenarchaeota	28889|Crenarchaeota	J	Binds to the 23S rRNA	rpl37e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
DPH1_k127_2234290_0	1236689.MMALV_13560	9.019e-146	475.0	COG0034@1|root,arCOG00093@2157|Archaea,2XSWJ@28890|Euryarchaeota,3F2FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
DPH1_k127_2234290_1	1041930.Mtc_0511	5.656e-77	269.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2NAF0@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DPH1_k127_2234290_7	438753.AZC_4705	2.521e-12	75.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,3EZW7@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	FR47-like protein	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
DPH1_k127_2234290_4	439481.Aboo_1281	1.531e-45	185.0	COG1094@1|root,arCOG04150@2157|Archaea,2XUHX@28890|Euryarchaeota,3F2NS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	K homology RNA-binding domain	dim2	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
DPH1_k127_2234290_3	1236689.MMALV_15340	1.153e-60	221.0	COG1718@1|root,arCOG01180@2157|Archaea,2XU2H@28890|Euryarchaeota,3F2PH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	RIO1 family	rio1	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
DPH1_k127_2237378_0	387631.Asulf_00521	6.113e-13	83.0	COG3979@1|root,COG5306@1|root,arCOG02420@1|root,arCOG03511@1|root,arCOG03553@1|root,arCOG09173@1|root,arCOG02420@2157|Archaea,arCOG03508@2157|Archaea,arCOG03511@2157|Archaea,arCOG03553@2157|Archaea,arCOG07581@2157|Archaea,arCOG09173@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF2341,PKD,Pilin_N,S_layer_C
DPH1_k127_2237378_1	246200.SPO0571	1.268e-05	58.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_2262631_2	1075090.GOAMR_62_00530	4.778e-08	64.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria	201174|Actinobacteria	S	Modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DPH1_k127_2262631_0	1183377.Py04_1772	1.952e-09	66.0	arCOG03797@1|root,arCOG03797@2157|Archaea,2Y8H0@28890|Euryarchaeota,24488@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
DPH1_k127_2262631_1	593750.Metfor_2178	1.025e-08	65.0	COG0640@1|root,COG0716@1|root,arCOG00519@2157|Archaea,arCOG01682@2157|Archaea,2XZ4A@28890|Euryarchaeota,2NBE1@224756|Methanomicrobia	224756|Methanomicrobia	K	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,Flavodoxin_4,HTH_5
DPH1_k127_2262631_3	671065.MetMK1DRAFT_00029480	1.75e-07	63.0	COG1931@1|root,arCOG01043@2157|Archaea,2XQU6@28889|Crenarchaeota	28889|Crenarchaeota	S	Belongs to the UPF0201 family	-	-	-	ko:K09736	-	-	-	-	ko00000	-	-	-	RNA_binding
DPH1_k127_2267171_1	1121918.ARWE01000001_gene1549	3.146e-18	97.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria,42VJ7@68525|delta/epsilon subdivisions,2WS0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
DPH1_k127_2267171_2	222984.JNCS01000002_gene1135	2.066e-05	58.0	COG2319@1|root,arCOG02490@2157|Archaea,2XUMP@28890|Euryarchaeota,23T2D@183963|Halobacteria	183963|Halobacteria	S	Pyrrolo-quinoline quinone	tup1	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
DPH1_k127_2267171_0	1123288.SOV_4c05150	2.833e-35	153.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,4H43Q@909932|Negativicutes	909932|Negativicutes	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_5
DPH1_k127_2319935_1	309798.COPRO5265_1261	8.192e-06	54.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,42GYR@68295|Thermoanaerobacterales	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
DPH1_k127_2319935_0	589924.Ferp_1620	6.716e-07	54.0	arCOG06113@1|root,arCOG06113@2157|Archaea,2Y130@28890|Euryarchaeota,246GP@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2331740_1	1121017.AUFG01000001_gene2897	0.000842	46.0	COG3052@1|root,COG3052@2|Bacteria,2GZPE@201174|Actinobacteria	201174|Actinobacteria	C	Covalent carrier of the coenzyme of citrate lyase	citD	-	-	ko:K01646	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001	-	-	-	ACP
DPH1_k127_2331740_0	395961.Cyan7425_1154	3.521e-45	183.0	COG0501@1|root,COG0501@2|Bacteria,1G16J@1117|Cyanobacteria,3KGMM@43988|Cyanothece	1117|Cyanobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
DPH1_k127_2336892_1	459349.CLOAM0437	4.06e-81	302.0	COG0457@1|root,COG0457@2|Bacteria	459349.CLOAM0437|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2336892_3	1121405.dsmv_0737	4.296e-10	74.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
DPH1_k127_2336892_0	1121091.AUMP01000002_gene1848	1.447e-133	449.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
DPH1_k127_2336892_2	439375.Oant_3517	1.084e-24	112.0	COG3153@1|root,COG3153@2|Bacteria,1MYY0@1224|Proteobacteria	1224|Proteobacteria	S	gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DPH1_k127_2347596_0	1054217.TALC_00683	1.32e-43	167.0	COG1591@1|root,arCOG00919@2157|Archaea,2XY2Q@28890|Euryarchaeota,241SS@183967|Thermoplasmata	183967|Thermoplasmata	L	Archaeal holliday junction resolvase (hjc)	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
DPH1_k127_2447841_0	1236689.MMALV_01480	5.812e-58	208.0	COG1339@1|root,arCOG01904@2157|Archaea,2XTFW@28890|Euryarchaeota,3F2NZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)	ribK	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase,HTH_20,HTH_24,HTH_Crp_2
DPH1_k127_2447841_1	309807.SRU_1887	3.488e-05	53.0	COG1470@1|root,COG1629@1|root,COG1470@2|Bacteria,COG4771@2|Bacteria,4PIBS@976|Bacteroidetes,1FJ71@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
DPH1_k127_2483013_2	348780.NP_2134A	0.0001492	49.0	COG0179@1|root,COG0454@1|root,arCOG00235@2157|Archaea,arCOG00839@2157|Archaea,2XU30@28890|Euryarchaeota,23T4G@183963|Halobacteria	183963|Halobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	hpcE1	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DPH1_k127_2483013_1	742725.HMPREF9450_00383	2.729e-116	385.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia,22VRM@171550|Rikenellaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DPH1_k127_2483013_0	545694.TREPR_1775	6.969e-236	750.0	COG0458@1|root,COG0458@2|Bacteria,2J6A8@203691|Spirochaetes	203691|Spirochaetes	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
DPH1_k127_2488211_0	886293.Sinac_4765	1.116e-60	243.0	COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes	203682|Planctomycetes	U	Pkd domain containing protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	-
DPH1_k127_2488211_1	679926.Mpet_0738	4.435e-11	67.0	COG1384@1|root,arCOG00485@2157|Archaea,2XTR5@28890|Euryarchaeota,2N9FV@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
DPH1_k127_2525354_0	1117319.PSPO_01605	3.354e-05	56.0	COG0747@1|root,COG4412@1|root,COG0747@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Big_5,SBP_bac_5
DPH1_k127_2529796_1	192952.MM_0591	5.928e-20	96.0	COG1967@1|root,arCOG02177@2157|Archaea,2XT8V@28890|Euryarchaeota,2N9NX@224756|Methanomicrobia	224756|Methanomicrobia	S	Membrane protein of unknown function DUF63	-	-	-	-	-	-	-	-	-	-	-	-	DUF63
DPH1_k127_2529796_0	1089553.Tph_c21120	2.959e-25	110.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DPH1_k127_2576671_1	589924.Ferp_0541	6.907e-30	126.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_2576671_0	439481.Aboo_0937	3.21e-36	145.0	COG0237@1|root,arCOG01045@2157|Archaea,2XWNJ@28890|Euryarchaeota,3F2R1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	AAA domain	coaE	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A0975	AAA_17,RNA_binding
DPH1_k127_2576671_2	339860.Msp_0197	0.0001583	55.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,23NSA@183925|Methanobacteria	183925|Methanobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DPH1_k127_2577207_0	877455.Metbo_0336	1.848e-104	351.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23NU5@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DPH1_k127_2582539_1	390989.JOEG01000017_gene6249	1.575e-15	88.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4DBWZ@85008|Micromonosporales	201174|Actinobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DPH1_k127_2582539_2	589924.Ferp_1102	9.685e-14	79.0	COG4738@1|root,arCOG04377@2157|Archaea,2XYIC@28890|Euryarchaeota,246AV@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2582539_0	479434.Sthe_1758	2.186e-54	203.0	COG0120@1|root,COG0120@2|Bacteria,2G6NN@200795|Chloroflexi,27Y9V@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
DPH1_k127_2613207_0	102129.Lepto7375DRAFT_0842	8.527e-19	102.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,1G4UG@1117|Cyanobacteria,1HH6U@1150|Oscillatoriales	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
DPH1_k127_2613207_1	1120950.KB892754_gene6015	6.065e-08	59.0	COG4747@1|root,COG4747@2|Bacteria,2GZWK@201174|Actinobacteria	201174|Actinobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2616379_0	1459636.NTE_00826	6.823e-38	155.0	COG0805@1|root,arCOG01919@2157|Archaea,41S69@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DPH1_k127_2616379_2	572546.Arcpr_1099	8.89e-11	67.0	COG1826@1|root,arCOG02694@2157|Archaea,2XZZ6@28890|Euryarchaeota,246CG@183980|Archaeoglobi	183980|Archaeoglobi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DPH1_k127_2616379_1	1235794.C811_02093	1.023e-14	79.0	COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,2I6HK@201174|Actinobacteria,4CUA7@84998|Coriobacteriia	84998|Coriobacteriia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	-	-	-	-	-	-	-	-	-	-	MobB,NTP_transf_3
DPH1_k127_2626269_2	401526.TcarDRAFT_1841	1.535e-82	295.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4H217@909932|Negativicutes	909932|Negativicutes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DPH1_k127_2626269_5	243231.GSU1722	1.199e-48	186.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WMNK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
DPH1_k127_2626269_4	1123253.AUBD01000004_gene1104	2.252e-49	185.0	COG1028@1|root,COG1028@2|Bacteria,1RI09@1224|Proteobacteria,1S78S@1236|Gammaproteobacteria,1X5ZY@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DPH1_k127_2626269_6	673860.AciM339_0977	4.846e-42	156.0	COG0051@1|root,arCOG01758@2157|Archaea,2XXV8@28890|Euryarchaeota,3F2QH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Involved in the binding of tRNA to the ribosomes	rps10	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DPH1_k127_2626269_1	368407.Memar_0730	2.124e-199	629.0	COG5256@1|root,arCOG01561@2157|Archaea,2XTNM@28890|Euryarchaeota,2N9FZ@224756|Methanomicrobia	224756|Methanomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DPH1_k127_2626269_0	673860.AciM339_0979	3.75e-322	1000.0	COG0480@1|root,arCOG01559@2157|Archaea,2XUMQ@28890|Euryarchaeota,3F2GN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DPH1_k127_2626269_3	1236689.MMALV_03250	2.223e-67	238.0	COG0049@1|root,arCOG04254@2157|Archaea,2XTDC@28890|Euryarchaeota,3F2JI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DPH1_k127_266292_1	1041930.Mtc_1472	2.055e-88	305.0	COG2379@1|root,arCOG04170@2157|Archaea,2XSTZ@28890|Euryarchaeota,2NAMM@224756|Methanomicrobia	224756|Methanomicrobia	G	Domain of unknown function (DUF4147)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
DPH1_k127_266292_0	552398.HMPREF0866_02341	2.677e-102	345.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DPH1_k127_2664702_1	378806.STAUR_2341	9.386e-30	139.0	COG2885@1|root,COG2931@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42T9J@68525|delta/epsilon subdivisions,2WU7T@28221|Deltaproteobacteria,2YWI9@29|Myxococcales	28221|Deltaproteobacteria	MQ	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
DPH1_k127_2664702_0	439481.Aboo_0846	2.645e-141	500.0	COG0017@1|root,arCOG00407@2157|Archaea,2XTZJ@28890|Euryarchaeota,3F37W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	class II (D K and N)	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DPH1_k127_2664702_2	1121481.AUAS01000003_gene3739	2.197e-15	92.0	COG2931@1|root,COG5184@1|root,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
DPH1_k127_2664702_3	604354.TSIB_0104	0.0001725	52.0	arCOG03799@1|root,arCOG03799@2157|Archaea,2Y3QV@28890|Euryarchaeota,244E7@183968|Thermococci	183968|Thermococci	T	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
DPH1_k127_2667686_0	313596.RB2501_13489	1.173e-36	161.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
DPH1_k127_2667686_1	317655.Sala_1915	8.038e-08	57.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,2K3WJ@204457|Sphingomonadales	204457|Sphingomonadales	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DPH1_k127_2674463_4	7370.XP_005187261.1	8.655e-10	74.0	KOG0613@1|root,KOG0613@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,41TW3@6656|Arthropoda,3SJ0H@50557|Insecta	33208|Metazoa	T	Immunoglobulin	sls	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000768,GO:0000793,GO:0000794,GO:0000819,GO:0002682,GO:0003674,GO:0003779,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005856,GO:0005859,GO:0005863,GO:0006323,GO:0006949,GO:0006996,GO:0007010,GO:0007049,GO:0007059,GO:0007062,GO:0007076,GO:0007275,GO:0007498,GO:0007517,GO:0007519,GO:0007520,GO:0007522,GO:0007525,GO:0008092,GO:0008150,GO:0008307,GO:0009653,GO:0009888,GO:0009987,GO:0010927,GO:0014706,GO:0014902,GO:0015629,GO:0016043,GO:0016203,GO:0016459,GO:0016460,GO:0022402,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030261,GO:0031032,GO:0031674,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032982,GO:0032989,GO:0032991,GO:0035206,GO:0036379,GO:0040011,GO:0042127,GO:0042692,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0044085,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045214,GO:0048285,GO:0048468,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0051146,GO:0051239,GO:0051276,GO:0055001,GO:0055002,GO:0060537,GO:0060538,GO:0061061,GO:0065007,GO:0070013,GO:0070925,GO:0071103,GO:0071840,GO:0097435,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:1903047	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	DUF1136,I-set,Ig_3,Pkinase,SH3_1,SH3_9,fn3
DPH1_k127_2674463_2	1280390.CBQR020000166_gene4414	4.641e-36	160.0	COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase family 6	guxA	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
DPH1_k127_2674463_0	717606.PaecuDRAFT_2033	1.796e-85	323.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_2674463_3	10224.XP_006823016.1	5.183e-34	154.0	KOG0613@1|root,KOG0613@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria	33208|Metazoa	T	myosin light chain kinase activity	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,fn3
DPH1_k127_2674463_1	1123252.ATZF01000027_gene1612	2.1e-79	303.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DPH1_k127_2719765_1	1343739.PAP_07630	9.87e-06	48.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,242WX@183968|Thermococci	183968|Thermococci	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DPH1_k127_2719765_0	324602.Caur_0392	7.48e-06	59.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,2GA7Y@200795|Chloroflexi,376PQ@32061|Chloroflexia	32061|Chloroflexia	M	SMART Parallel beta-helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NPCBM_assoc
DPH1_k127_2725535_2	1121017.AUFG01000002_gene2851	5.662e-17	93.0	COG0697@1|root,COG0697@2|Bacteria,2GNSA@201174|Actinobacteria,4FFJ5@85021|Intrasporangiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_2725535_0	1210908.HSB1_25580	1.333e-39	164.0	COG0477@1|root,arCOG00131@2157|Archaea,2XUXU@28890|Euryarchaeota,23U5F@183963|Halobacteria	183963|Halobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_2725535_1	502025.Hoch_3973	2.06e-37	144.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2YURX@29|Myxococcales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DPH1_k127_2767380_0	768706.Desor_3043	5.368e-151	487.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2611H@186807|Peptococcaceae	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_2767380_2	1449126.JQKL01000002_gene1588	2.461e-100	334.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DPH1_k127_2767380_1	1449126.JQKL01000090_gene491	3.949e-130	438.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
DPH1_k127_2767380_3	1150474.JQJI01000017_gene593	7.509e-23	104.0	COG1661@1|root,COG1661@2|Bacteria,2GDE0@200918|Thermotogae	200918|Thermotogae	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
DPH1_k127_2769231_1	439481.Aboo_0227	1.732e-53	203.0	COG1650@1|root,arCOG01616@2157|Archaea,2XUM0@28890|Euryarchaeota,3F2M2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
DPH1_k127_2769231_0	673860.AciM339_0095	5.435e-68	240.0	COG1859@1|root,arCOG04063@2157|Archaea,2XWPC@28890|Euryarchaeota,3F2KG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
DPH1_k127_2769231_2	502025.Hoch_3823	0.000996	52.0	COG0515@1|root,COG1672@1|root,COG2319@1|root,COG0515@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,4328Z@68525|delta/epsilon subdivisions,2X7NM@28221|Deltaproteobacteria,2YXMY@29|Myxococcales	28221|Deltaproteobacteria	T	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Peptidase_C14,Pkinase,WD40
DPH1_k127_2781357_0	1123508.JH636439_gene1383	3.138e-15	91.0	COG0526@1|root,COG0526@2|Bacteria,2IZ08@203682|Planctomycetes	203682|Planctomycetes	CO	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2781357_3	1227352.C173_08606	1.331e-06	62.0	COG5297@1|root,COG5297@2|Bacteria,1TXPR@1239|Firmicutes,4I6QI@91061|Bacilli,26UAT@186822|Paenibacillaceae	91061|Bacilli	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
DPH1_k127_2781357_1	1042877.GQS_04115	5.452e-15	90.0	COG3291@1|root,arCOG05839@1|root,arCOG02508@2157|Archaea,arCOG05839@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,PKD,Pilin_N,SdrD_B
DPH1_k127_2781357_2	1298863.AUEP01000001_gene765	9.793e-13	82.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4DP00@85009|Propionibacteriales	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,Malectin,PKD
DPH1_k127_2827746_1	345341.KUTG_01110	1.134e-11	74.0	COG2230@1|root,COG2230@2|Bacteria,2IAU4@201174|Actinobacteria,4EDQA@85010|Pseudonocardiales	201174|Actinobacteria	M	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DPH1_k127_2827746_0	985054.JQEZ01000001_gene1782	3.029e-17	95.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_2866091_1	693661.Arcve_1349	1.989e-06	50.0	COG0195@1|root,arCOG01760@2157|Archaea,2XYAY@28890|Euryarchaeota,2468I@183980|Archaeoglobi	183980|Archaeoglobi	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
DPH1_k127_2866091_0	416348.Hlac_2824	2.277e-54	214.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_2905221_0	673860.AciM339_0591	1.735e-27	122.0	COG0125@1|root,arCOG01891@2157|Archaea,2XTAM@28890|Euryarchaeota,3F2RW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Thymidylate kinase	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DPH1_k127_2962478_1	1157632.AQWQ01000002_gene4060	0.0002013	55.0	COG3227@1|root,COG3979@1|root,COG3227@2|Bacteria,COG3979@2|Bacteria,2IDQA@201174|Actinobacteria	201174|Actinobacteria	E	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	FTP,He_PIG,P_proprotein,Peptidase_M4,Peptidase_M4_C
DPH1_k127_2962478_0	1236689.MMALV_16780	1.018e-34	147.0	COG1499@1|root,arCOG04149@2157|Archaea,2XUAI@28890|Euryarchaeota,3F2MW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	NMD3 family	nmd3	-	-	ko:K07562	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko03009	-	-	-	NMD3
DPH1_k127_29839_3	714943.Mucpa_1036	6.349e-06	61.0	COG1470@1|root,COG1470@2|Bacteria,4NHIX@976|Bacteroidetes,1IQI7@117747|Sphingobacteriia	976|Bacteroidetes	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
DPH1_k127_29839_0	1094980.Mpsy_0983	1.324e-75	290.0	COG1404@1|root,arCOG02538@1|root,arCOG03439@1|root,arCOG00702@2157|Archaea,arCOG02538@2157|Archaea,arCOG03439@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Calx-beta,Inhibitor_I9,Peptidase_S8
DPH1_k127_29839_1	1196323.ALKF01000178_gene230	1.072e-64	254.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,1TQRU@1239|Firmicutes,4HV3C@91061|Bacilli,26VJF@186822|Paenibacillaceae	91061|Bacilli	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
DPH1_k127_29839_2	338966.Ppro_0054	9.086e-10	66.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,42WF6@68525|delta/epsilon subdivisions,2WS8U@28221|Deltaproteobacteria,43U1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_2,TPR_8
DPH1_k127_301490_1	502558.EGYY_18700	1.279e-09	62.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CVSK@84998|Coriobacteriia	84998|Coriobacteriia	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR,PLDc_N,zinc_ribbon_2
DPH1_k127_301490_0	1089551.KE386572_gene1743	4.074e-51	210.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria,4BRG6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_3025920_3	1054217.TALC_01427	1.384e-24	105.0	COG2139@1|root,arCOG04129@2157|Archaea,2XXZB@28890|Euryarchaeota,241X7@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	-	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
DPH1_k127_3025920_4	593750.Metfor_1113	2.092e-13	78.0	COG1460@1|root,arCOG01016@2157|Archaea,2XXZX@28890|Euryarchaeota,2N9UM@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM RNA polymerase Rpb4	rpoF	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
DPH1_k127_3025920_0	673860.AciM339_0303	2.271e-67	234.0	COG1491@1|root,arCOG04130@2157|Archaea,2XXAI@28890|Euryarchaeota,3F2KH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Helix-hairpin-helix motif	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
DPH1_k127_3025920_1	1054217.TALC_01430	1.452e-47	189.0	COG0030@1|root,arCOG04131@2157|Archaea,2XU1Q@28890|Euryarchaeota,241VH@183967|Thermoplasmata	183967|Thermoplasmata	J	Ribosomal RNA adenine dimethylases	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DPH1_k127_3025920_5	1032480.MLP_39940	5.315e-10	70.0	COG2227@1|root,COG2227@2|Bacteria,2I7CR@201174|Actinobacteria	201174|Actinobacteria	H	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DPH1_k127_3025920_2	1094980.Mpsy_3151	5.914e-35	150.0	COG5520@1|root,arCOG03769@1|root,arCOG07561@1|root,arCOG03769@2157|Archaea,arCOG07561@2157|Archaea,arCOG09138@2157|Archaea,2XV3J@28890|Euryarchaeota,2NBAU@224756|Methanomicrobia	224756|Methanomicrobia	K	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3083216_0	195522.BD01_1271	1.244e-36	156.0	COG0477@1|root,arCOG00132@2157|Archaea,2XYHV@28890|Euryarchaeota,242TF@183968|Thermococci	183968|Thermococci	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_3083216_2	269797.Mbar_A1166	1.925e-07	59.0	arCOG03097@1|root,arCOG03097@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3083216_1	574087.Acear_1558	5.527e-16	87.0	COG1266@1|root,COG1266@2|Bacteria,1V4WD@1239|Firmicutes,24P4C@186801|Clostridia	186801|Clostridia	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DPH1_k127_3083237_5	316067.Geob_0106	3.55e-05	46.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,43TIS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	pcmT	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DPH1_k127_3083237_0	555079.Toce_1851	4.291e-184	589.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,42FP5@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
DPH1_k127_3083237_1	635013.TherJR_2984	2.158e-148	484.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,260KK@186807|Peptococcaceae	186801|Clostridia	E	PFAM Peptidase M18, aminopeptidase I	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
DPH1_k127_3083237_2	1293048.CBMB010000010_gene3725	6.838e-42	179.0	COG1520@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02556@2157|Archaea,2XZQY@28890|Euryarchaeota,23X43@183963|Halobacteria	183963|Halobacteria	S	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DPH1_k127_3083237_3	1249997.JHZW01000003_gene2150	2.86e-14	88.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4PI47@976|Bacteroidetes,1IM97@117743|Flavobacteriia,2PI57@252356|Maribacter	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
DPH1_k127_3083237_4	1121439.dsat_1833	1.417e-07	61.0	2EEAU@1|root,33859@2|Bacteria,1NPX9@1224|Proteobacteria,4367D@68525|delta/epsilon subdivisions,2X0RQ@28221|Deltaproteobacteria,2MD7Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3085951_0	1041930.Mtc_0311	1.859e-103	374.0	COG2409@1|root,arCOG02175@2157|Archaea,2XVKJ@28890|Euryarchaeota	28890|Euryarchaeota	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
DPH1_k127_3085951_2	1245475.ANAE01000117_gene2406	1.977e-06	62.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria,4EM6C@85012|Streptosporangiales	201174|Actinobacteria	O	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Beta_helix
DPH1_k127_3085951_1	1392489.JPOL01000002_gene2745	9.595e-08	66.0	COG2133@1|root,COG2911@1|root,COG3291@1|root,COG4932@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4PKJH@976|Bacteroidetes,1IJAY@117743|Flavobacteriia	976|Bacteroidetes	G	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PKD
DPH1_k127_3150949_1	439481.Aboo_0024	1.547e-46	173.0	COG2238@1|root,arCOG01344@2157|Archaea,2XXA6@28890|Euryarchaeota,3F2P6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
DPH1_k127_3150949_2	673860.AciM339_0026	6.98e-23	103.0	COG2118@1|root,arCOG04179@2157|Archaea,2XZUR@28890|Euryarchaeota,3F2TE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Belongs to the PDCD5 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
DPH1_k127_3150949_4	868131.MSWAN_1846	4.85e-12	68.0	COG2167@1|root,arCOG04177@2157|Archaea,2Y79Z@28890|Euryarchaeota,23PV2@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	-	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
DPH1_k127_3150949_3	572478.Vdis_2538	4.306e-19	91.0	COG2097@1|root,arCOG04473@2157|Archaea,2XR1E@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the ribosomal protein L31e family	rpl31e	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
DPH1_k127_3150949_0	351160.RCIX1042	2.005e-56	204.0	COG1976@1|root,arCOG04176@2157|Archaea,2XU7N@28890|Euryarchaeota,2N9JT@224756|Methanomicrobia	224756|Methanomicrobia	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	-	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
DPH1_k127_3153256_3	639282.DEFDS_0177	5.893e-38	151.0	COG0755@1|root,COG0755@2|Bacteria,2GF7F@200930|Deferribacteres	200930|Deferribacteres	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
DPH1_k127_3153256_5	192952.MM_2397	5.139e-28	129.0	COG2386@1|root,arCOG01328@2157|Archaea,2XTAS@28890|Euryarchaeota,2NAJD@224756|Methanomicrobia	224756|Methanomicrobia	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
DPH1_k127_3153256_2	742742.HMPREF9452_01051	1.163e-54	201.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria,4CYEJ@84998|Coriobacteriia	84998|Coriobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DPH1_k127_3153256_4	1869.MB27_26355	3.771e-28	127.0	COG0382@1|root,COG0382@2|Bacteria,2IJV5@201174|Actinobacteria,4DGXV@85008|Micromonosporales	201174|Actinobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_3153256_0	1054217.TALC_01537	6.15e-112	375.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota,242ID@183967|Thermoplasmata	28890|Euryarchaeota	C	4Fe-4S dicluster domain	hdrD	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
DPH1_k127_3153256_1	1054217.TALC_00487	4.554e-106	373.0	COG0277@1|root,arCOG00340@2157|Archaea,2XVP5@28890|Euryarchaeota	28890|Euryarchaeota	C	FAD binding domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
DPH1_k127_3153256_7	415426.Hbut_1053	6.787e-06	57.0	arCOG05636@1|root,arCOG05636@2157|Archaea,2XRH9@28889|Crenarchaeota	28889|Crenarchaeota	C	Prokaryotic cytochrome b561	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
DPH1_k127_3153256_6	1121866.AUGK01000005_gene1167	5.146e-12	78.0	COG3303@1|root,COG3303@2|Bacteria,2HUW7@201174|Actinobacteria,4CVUR@84998|Coriobacteriia	84998|Coriobacteriia	P	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
DPH1_k127_3153256_8	365528.KB891213_gene2507	0.0006148	46.0	COG0500@1|root,COG0500@2|Bacteria,2GX4K@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DPH1_k127_3200841_0	706587.Desti_4338	1.134e-178	565.0	COG2502@1|root,COG2502@2|Bacteria,1MVWF@1224|Proteobacteria	1224|Proteobacteria	E	aspartate--ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA,tRNA-synt_2
DPH1_k127_3200841_1	1236689.MMALV_11680	8.757e-49	182.0	COG0717@1|root,arCOG04048@2157|Archaea,2Y6XJ@28890|Euryarchaeota,3F2QT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
DPH1_k127_3218287_0	269799.Gmet_1998	3.584e-08	67.0	COG1305@1|root,COG1572@1|root,COG1305@2|Bacteria,COG1572@2|Bacteria,1NZT4@1224|Proteobacteria,4322D@68525|delta/epsilon subdivisions,2WWXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_321999_3	673860.AciM339_0609	9.851e-19	94.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota,3F33E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpD
DPH1_k127_321999_1	439481.Aboo_0654	1.387e-35	155.0	arCOG00373@1|root,arCOG02452@1|root,arCOG00373@2157|Archaea,arCOG02452@2157|Archaea,2Y71H@28890|Euryarchaeota,3F35U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_321999_2	673860.AciM339_0382	1.039e-31	129.0	COG1196@1|root,arCOG01917@1|root,arCOG02452@1|root,arCOG00371@2157|Archaea,arCOG01917@2157|Archaea,arCOG02452@2157|Archaea,2Y71H@28890|Euryarchaeota,3F35U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_321999_0	1236689.MMALV_01460	1.15e-256	814.0	COG0046@1|root,arCOG00641@2157|Archaea,2XU49@28890|Euryarchaeota,3F2HX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0536	AIRS,AIRS_C
DPH1_k127_321999_4	589924.Ferp_1508	3.043e-17	85.0	COG1828@1|root,arCOG04462@2157|Archaea,2XYPB@28890|Euryarchaeota,246HY@183980|Archaeoglobi	183980|Archaeoglobi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DPH1_k127_3222032_1	1125779.HMPREF1219_02169	6.018e-21	110.0	COG3064@1|root,COG3147@1|root,COG4625@1|root,COG4932@1|root,COG3064@2|Bacteria,COG3147@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria,2IC22@201174|Actinobacteria,22MBB@1653|Corynebacteriaceae	201174|Actinobacteria	M	Rib/alpha-like repeat	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	He_PIG,Rib
DPH1_k127_3222032_3	374847.Kcr_0417	4.755e-16	94.0	arCOG02499@1|root,arCOG02499@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
DPH1_k127_3222032_0	1227352.C173_10545	2.834e-28	122.0	COG4186@1|root,COG4186@2|Bacteria,1V6DG@1239|Firmicutes,4HPXG@91061|Bacilli,26VH5@186822|Paenibacillaceae	91061|Bacilli	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
DPH1_k127_3222032_2	357808.RoseRS_1520	2.663e-19	104.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
DPH1_k127_3230985_0	273075.Ta0351	5.423e-92	314.0	COG0183@1|root,arCOG01280@2157|Archaea,2Y85P@28890|Euryarchaeota,241YR@183967|Thermoplasmata	183967|Thermoplasmata	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DPH1_k127_3230985_1	443143.GM18_2087	2.88e-27	125.0	COG1545@1|root,COG1545@2|Bacteria,1NPAR@1224|Proteobacteria,42WW8@68525|delta/epsilon subdivisions,2WSYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DPH1_k127_3297853_1	673860.AciM339_0566	2.995e-121	398.0	COG0731@1|root,arCOG04174@2157|Archaea,2XSTF@28890|Euryarchaeota,3F2ET@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
DPH1_k127_3297853_0	439481.Aboo_0122	2.25e-257	808.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,3F2GJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	KH domain	epf2	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
DPH1_k127_3297853_2	673860.AciM339_0925	6.173e-64	226.0	COG0638@1|root,arCOG00970@2157|Archaea,2XUIZ@28890|Euryarchaeota,3F2PC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
DPH1_k127_3308814_0	439481.Aboo_0181	2.705e-85	289.0	COG2123@1|root,arCOG01574@2157|Archaea,2XWTK@28890|Euryarchaeota,3F2JS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DPH1_k127_3308814_1	439481.Aboo_0180	7.24e-17	85.0	COG1997@1|root,arCOG04208@2157|Archaea,2Y6HQ@28890|Euryarchaeota,3F2TK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
DPH1_k127_3308814_3	1236689.MMALV_02950	1.026e-08	57.0	COG1996@1|root,arCOG04341@2157|Archaea,2Y5VN@28890|Euryarchaeota	28890|Euryarchaeota	K	DNA directed RNA polymerase, 7 kDa subunit	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	DNA_RNApol_7kD
DPH1_k127_3308814_2	269797.Mbar_A0213	2.045e-09	67.0	COG1382@1|root,arCOG01342@2157|Archaea,2XX88@28890|Euryarchaeota,2N9TP@224756|Methanomicrobia	224756|Methanomicrobia	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
DPH1_k127_3333779_1	103733.JNYO01000043_gene5872	1.758e-35	154.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DXRX@85010|Pseudonocardiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
DPH1_k127_3333779_0	69014.TK0550	4.763e-168	541.0	COG0008@1|root,arCOG00402@2157|Archaea,2XSUM@28890|Euryarchaeota,242RZ@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DPH1_k127_3333779_3	673860.AciM339_0336	1.494e-07	56.0	arCOG05340@1|root,arCOG05340@2157|Archaea,2Y77S@28890|Euryarchaeota,3F3IY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3333779_2	673860.AciM339_0863	1.861e-09	58.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,3F2II@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
DPH1_k127_3391664_0	797303.Natpe_2401	2.526e-30	136.0	COG1784@1|root,arCOG04469@2157|Archaea,2XSZ3@28890|Euryarchaeota,23SUU@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	ko:K08971	-	-	-	-	ko00000	-	-	-	TctA
DPH1_k127_3448116_2	706587.Desti_0171	3.924e-36	147.0	COG1150@1|root,COG1150@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitrate reductase gamma subunit	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DPH1_k127_3448116_1	706587.Desti_0172	2.063e-72	254.0	COG2048@1|root,COG2048@2|Bacteria,1RC7G@1224|Proteobacteria,43B85@68525|delta/epsilon subdivisions,2WMVG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Heterodisulfide reductase subunit B	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DPH1_k127_3448116_0	429009.Adeg_1333	1.654e-111	388.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,42FM3@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
DPH1_k127_3458536_9	1187851.A33M_0913	3.989e-06	49.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,3FCG0@34008|Rhodovulum	28211|Alphaproteobacteria	J	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DPH1_k127_3458536_10	402777.KB235898_gene5332	7.68e-06	53.0	COG5550@1|root,COG5550@2|Bacteria,1G73D@1117|Cyanobacteria,1HH2Y@1150|Oscillatoriales	1117|Cyanobacteria	O	Clan AA aspartic protease	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3458536_3	439481.Aboo_0657	1.009e-82	288.0	COG0603@1|root,arCOG00039@2157|Archaea,2XTS7@28890|Euryarchaeota,3F2JU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
DPH1_k127_3458536_5	673860.AciM339_1056	3.089e-54	208.0	COG0602@1|root,arCOG02173@2157|Archaea,2XUSP@28890|Euryarchaeota,3F2KS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
DPH1_k127_3458536_8	693661.Arcve_1550	6.372e-21	108.0	COG0640@1|root,arCOG01683@2157|Archaea,2Y0SK@28890|Euryarchaeota,2476X@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DPH1_k127_3458536_2	304371.MCP_2614	3.278e-113	373.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,2N989@224756|Methanomicrobia	224756|Methanomicrobia	C	thiamine pyrophosphate enzyme domain protein TPP-binding	porB-1	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DPH1_k127_3458536_0	304371.MCP_2613	4.639e-129	426.0	COG0674@1|root,arCOG01608@2157|Archaea,2XTB0@28890|Euryarchaeota,2N98Z@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	porA-1	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DPH1_k127_3458536_7	604354.TSIB_1380	1.647e-26	112.0	COG1144@1|root,arCOG01605@2157|Archaea,2Y02N@28890|Euryarchaeota,24454@183968|Thermococci	183968|Thermococci	C	oxidoreductase subunit delta	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6
DPH1_k127_3458536_4	192952.MM_1342	3.504e-63	223.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,2N9J1@224756|Methanomicrobia	224756|Methanomicrobia	C	TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit	porC-1	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
DPH1_k127_3458536_6	1457250.BBMO01000001_gene1581	2.356e-37	163.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_3458536_1	1121472.AQWN01000002_gene2159	8.117e-115	382.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DPH1_k127_3471106_0	28072.Nos7524_5484	6.428e-17	96.0	COG2304@1|root,COG3209@1|root,COG3210@1|root,COG3266@1|root,COG5276@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG5276@2|Bacteria,1G4UG@1117|Cyanobacteria	1117|Cyanobacteria	M	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
DPH1_k127_3471106_1	324602.Caur_1238	9.515e-12	79.0	COG2823@1|root,COG5297@1|root,COG2823@2|Bacteria,COG5297@2|Bacteria,2GA85@200795|Chloroflexi,376AG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3474356_0	273116.14324649	5.361e-27	117.0	arCOG03678@1|root,arCOG03677@2157|Archaea,2Y0K5@28890|Euryarchaeota,242AH@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3474356_1	290397.Adeh_1133	2.659e-24	108.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DPH1_k127_3531508_0	1293054.HSACCH_01865	1.099e-89	313.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WAG5@53433|Halanaerobiales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DPH1_k127_3531563_1	765420.OSCT_0431	9.917e-36	141.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi,375RE@32061|Chloroflexia	32061|Chloroflexia	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DPH1_k127_3531563_0	529709.PYCH_12070	1.224e-37	146.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DPH1_k127_3531563_2	368407.Memar_1711	1.244e-31	141.0	COG0644@1|root,arCOG00570@2157|Archaea,2XWXQ@28890|Euryarchaeota,2N9RD@224756|Methanomicrobia	224756|Methanomicrobia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DPH1_k127_3531563_3	251221.35214790	3.199e-21	108.0	COG2133@1|root,COG3391@1|root,COG2133@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276,ko:K21430	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
DPH1_k127_3540872_0	1129794.C427_1223	4.551e-25	121.0	COG2706@1|root,COG3391@1|root,COG3637@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,COG3637@2|Bacteria,1QWRQ@1224|Proteobacteria,1T4S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3540872_1	1121104.AQXH01000001_gene943	5.265e-09	70.0	COG3291@1|root,COG3291@2|Bacteria,4PKJH@976|Bacteroidetes	976|Bacteroidetes	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PKD
DPH1_k127_3550342_0	693661.Arcve_1931	1.437e-70	247.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,2460M@183980|Archaeoglobi	183980|Archaeoglobi	E	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_3550342_1	1121928.AUHE01000001_gene1732	6.361e-05	56.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4GAND@85026|Gordoniaceae	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_3583218_0	1224136.AMFN01000014_gene2474	3.845e-06	59.0	COG2911@1|root,COG2911@2|Bacteria,1P8N9@1224|Proteobacteria,1T1IH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,VCBS
DPH1_k127_3597672_5	870187.Thini_1774	6.405e-13	81.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,1RS7G@1236|Gammaproteobacteria,46256@72273|Thiotrichales	72273|Thiotrichales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DPH1_k127_3597672_1	523845.AQXV01000026_gene1469	3.634e-82	309.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
DPH1_k127_3597672_6	1236689.MMALV_08100	1.764e-11	72.0	arCOG03379@1|root,arCOG03379@2157|Archaea,2XZH1@28890|Euryarchaeota,3F2PN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3597672_2	269797.Mbar_A2751	4.645e-46	189.0	arCOG02527@1|root,arCOG02527@2157|Archaea,2Y6XK@28890|Euryarchaeota,2NAMP@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3597672_3	401526.TcarDRAFT_0813	4.468e-38	154.0	COG1335@1|root,COG1335@2|Bacteria,1V5TQ@1239|Firmicutes	1239|Firmicutes	Q	isochorismatase	entB	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DPH1_k127_3597672_4	673860.AciM339_1537	6.613e-31	128.0	COG1813@1|root,arCOG01863@2157|Archaea,2XXND@28890|Euryarchaeota,3F2TJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
DPH1_k127_3597672_0	572546.Arcpr_1629	2.615e-155	500.0	COG1222@1|root,arCOG01306@2157|Archaea,2XTB6@28890|Euryarchaeota,246U9@183980|Archaeoglobi	183980|Archaeoglobi	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates	pan	-	-	ko:K03420	ko03050,map03050	M00343	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA
DPH1_k127_3600986_0	717606.PaecuDRAFT_2033	3.603e-100	367.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_3600986_1	1386089.N865_05350	1.337e-55	224.0	COG4733@1|root,COG4733@2|Bacteria,2I7XV@201174|Actinobacteria,4FK2V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DPH1_k127_3625900_0	439481.Aboo_0148	2.862e-112	371.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,3F37Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DPH1_k127_3625900_1	1094980.Mpsy_2607	6.736e-40	164.0	COG1305@1|root,arCOG03600@2157|Archaea,2Y7F7@28890|Euryarchaeota,2NA6Q@224756|Methanomicrobia	224756|Methanomicrobia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DPH1_k127_3643279_0	5888.CAK87026	2.811e-57	221.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
DPH1_k127_3655075_0	673860.AciM339_0004	4.691e-59	221.0	COG0010@1|root,arCOG01700@2157|Archaea,2XTEP@28890|Euryarchaeota,3F2M6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DPH1_k127_3655075_2	673860.AciM339_0003	1.743e-44	164.0	COG0231@1|root,arCOG04277@2157|Archaea,2XX3E@28890|Euryarchaeota,3F2PU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	EFP_N,eIF-5a
DPH1_k127_3655075_1	673860.AciM339_0972	1.016e-46	185.0	COG0483@1|root,arCOG01349@2157|Archaea,2Y87S@28890|Euryarchaeota,3F2MR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DPH1_k127_3660471_0	673860.AciM339_0292	5.303e-69	269.0	COG4870@1|root,arCOG02501@1|root,arCOG03439@1|root,arCOG02501@2157|Archaea,arCOG03439@2157|Archaea,arCOG03614@2157|Archaea,2XZI4@28890|Euryarchaeota	28890|Euryarchaeota	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DPH1_k127_3660471_3	1249997.JHZW01000003_gene2150	2.48e-14	89.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4PI47@976|Bacteroidetes,1IM97@117743|Flavobacteriia,2PI57@252356|Maribacter	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
DPH1_k127_3660471_1	429009.Adeg_1691	2.756e-44	168.0	COG4739@1|root,COG4739@2|Bacteria,1V3K5@1239|Firmicutes,24INA@186801|Clostridia,42FIV@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148
DPH1_k127_3660471_2	192952.MM_2039	1.792e-32	130.0	COG2007@1|root,arCOG04154@2157|Archaea,2XYXX@28890|Euryarchaeota,2N9UK@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM ribosomal protein S8E	rps8e	-	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
DPH1_k127_3660471_4	456442.Mboo_2309	4.363e-14	77.0	COG1400@1|root,arCOG01217@2157|Archaea,2Y68X@28890|Euryarchaeota,2NA5V@224756|Methanomicrobia	224756|Methanomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP	srp19	-	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
DPH1_k127_3712226_0	401526.TcarDRAFT_1353	9.221e-133	436.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H24N@909932|Negativicutes	909932|Negativicutes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DPH1_k127_3712226_1	425104.Ssed_2704	6.667e-21	103.0	COG1184@1|root,COG1184@2|Bacteria	2|Bacteria	J	translation initiation factor activity	-	-	-	ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
DPH1_k127_3718066_2	521011.Mpal_0492	4.216e-55	199.0	COG1584@1|root,arCOG03176@2157|Archaea,2XWNC@28890|Euryarchaeota,2N9MY@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM GPR1 FUN34 yaaH family	-	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
DPH1_k127_3718066_1	1236689.MMALV_01900	4.947e-101	359.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,3F2M9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DPH1_k127_3718066_0	401526.TcarDRAFT_1976	6.17e-207	658.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4H1XW@909932|Negativicutes	909932|Negativicutes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
DPH1_k127_3748724_0	1121481.AUAS01000003_gene3739	3.557e-49	203.0	COG2931@1|root,COG5184@1|root,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
DPH1_k127_3748724_1	1298863.AUEP01000001_gene908	1.36e-28	136.0	COG1629@1|root,COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG4771@2|Bacteria,COG5297@2|Bacteria,2I7N8@201174|Actinobacteria	201174|Actinobacteria	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3753519_6	335543.Sfum_1176	1.172e-67	245.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
DPH1_k127_3753519_0	706587.Desti_0010	0.0	1023.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria,2MR5E@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NAD(P)-binding Rossmann-like domain	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,FlpD,Pyr_redox_2
DPH1_k127_3753519_17	1179773.BN6_60160	0.0001731	55.0	COG1361@1|root,COG2373@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
DPH1_k127_3753519_11	1521187.JPIM01000001_gene835	2.454e-13	84.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,2GA7Y@200795|Chloroflexi,376PQ@32061|Chloroflexia	32061|Chloroflexia	M	SMART Parallel beta-helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NPCBM_assoc
DPH1_k127_3753519_9	945713.IALB_0393	6.63e-40	156.0	COG2324@1|root,COG2324@2|Bacteria	2|Bacteria	S	Carotenoid biosynthesis protein	cruF	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
DPH1_k127_3753519_3	368407.Memar_0117	5.17e-97	324.0	COG1562@1|root,arCOG02936@2157|Archaea,2XTG2@28890|Euryarchaeota	28890|Euryarchaeota	I	Phytoene squalene synthetase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
DPH1_k127_3753519_1	889378.Spiaf_1662	8.256e-190	608.0	COG1233@1|root,COG1233@2|Bacteria,2J5I9@203691|Spirochaetes	203691|Spirochaetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37	ko:K10027,ko:K20611	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DPH1_k127_3753519_8	945713.IALB_0397	7.371e-51	190.0	arCOG05416@1|root,2ZZTD@2|Bacteria	2|Bacteria	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_3753519_7	368407.Memar_2408	1.774e-54	203.0	COG1575@1|root,arCOG00480@2157|Archaea,2XXM6@28890|Euryarchaeota	28890|Euryarchaeota	H	PFAM UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_3753519_12	589924.Ferp_2499	2.73e-10	67.0	COG1180@1|root,arCOG00947@2157|Archaea,2XWY1@28890|Euryarchaeota,246TQ@183980|Archaeoglobi	183980|Archaeoglobi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
DPH1_k127_3753519_16	387631.Asulf_01333	2.779e-05	53.0	COG1708@1|root,arCOG01208@2157|Archaea,2Y0ZT@28890|Euryarchaeota	28890|Euryarchaeota	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
DPH1_k127_3753519_19	386456.JQKN01000001_gene2286	0.0003059	46.0	COG1895@1|root,arCOG02123@2157|Archaea,2Y56Q@28890|Euryarchaeota	28890|Euryarchaeota	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
DPH1_k127_3753519_13	368407.Memar_2114	1.919e-08	59.0	COG1895@1|root,arCOG02123@2157|Archaea,2Y56Q@28890|Euryarchaeota,2NBDH@224756|Methanomicrobia	224756|Methanomicrobia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
DPH1_k127_3753519_5	694429.Pyrfu_1862	1.659e-73	266.0	COG1180@1|root,arCOG00947@2157|Archaea,2XPYQ@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
DPH1_k127_3753519_14	1117647.M5M_14925	1.422e-06	62.0	COG3291@1|root,COG3397@1|root,COG3291@2|Bacteria,COG3397@2|Bacteria,1QUSE@1224|Proteobacteria,1T4GG@1236|Gammaproteobacteria,1JC3E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CBD_II	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,PKD
DPH1_k127_3753519_18	1121377.KB906434_gene693	0.0002671	55.0	COG2885@1|root,COG4386@1|root,COG2885@2|Bacteria,COG4386@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K16191,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6.1.3	-	-	Big_3_2,CHU_C,Calx-beta,DUF11,OmpA
DPH1_k127_3753519_2	1123008.KB905696_gene2997	4.057e-103	347.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,2FM2M@200643|Bacteroidia,22WBA@171551|Porphyromonadaceae	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
DPH1_k127_3753519_4	673860.AciM339_1144	2.731e-96	331.0	COG0045@1|root,arCOG01337@2157|Archaea,2XTSC@28890|Euryarchaeota,3F389@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	ATP-grasp domain	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DPH1_k127_3753519_15	1006006.Mcup_1387	3.884e-06	52.0	COG1599@1|root,arCOG01510@2157|Archaea,2XQQM@28889|Crenarchaeota	28889|Crenarchaeota	L	PFAM nucleic acid binding, OB-fold, tRNA helicase-type	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
DPH1_k127_3753519_10	1382356.JQMP01000003_gene2551	5.571e-30	129.0	COG1515@1|root,COG1515@2|Bacteria,2G6SS@200795|Chloroflexi,27Y9X@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
DPH1_k127_375818_1	1457250.BBMO01000001_gene1581	2.612e-125	447.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_375818_5	215803.DB30_0610	1.061e-13	86.0	COG2854@1|root,COG2854@2|Bacteria	2|Bacteria	Q	intermembrane phospholipid transfer	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
DPH1_k127_375818_2	1047013.AQSP01000105_gene1451	1.669e-117	394.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DPH1_k127_375818_3	457570.Nther_0880	1.78e-43	163.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_1,Flavodoxin_5
DPH1_k127_375818_4	1537994.JQFW01000031_gene1084	3.569e-18	101.0	COG2373@1|root,COG2911@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,1P8N9@1224|Proteobacteria,1T1IH@1236|Gammaproteobacteria,465B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Bacterial Ig-like domain (group 3)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3
DPH1_k127_375818_0	1041930.Mtc_0274	1.163e-125	409.0	COG1257@1|root,arCOG04260@2157|Archaea,2XTV9@28890|Euryarchaeota	28890|Euryarchaeota	I	Belongs to the HMG-CoA reductase family	hmgA-1	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
DPH1_k127_375912_7	1121363.KB902235_gene1443	6.179e-05	45.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,22MWH@1653|Corynebacteriaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DPH1_k127_375912_8	1323663.AROI01000031_gene1925	8.172e-05	47.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DPH1_k127_375912_4	1203611.KB894541_gene1268	2.35e-30	124.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,2FSA5@200643|Bacteroidia,22VA7@171550|Rikenellaceae	976|Bacteroidetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DPH1_k127_375912_5	383372.Rcas_0555	4.86e-14	87.0	COG2152@1|root,COG2152@2|Bacteria,2G86G@200795|Chloroflexi,376E1@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DPH1_k127_375912_1	1347368.HG964403_gene4490	2.865e-63	250.0	COG4632@1|root,COG5492@1|root,COG4632@2|Bacteria,COG5492@2|Bacteria,1V706@1239|Firmicutes,4IQJJ@91061|Bacilli	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_375912_2	1205753.A989_00025	1.256e-43	171.0	COG0500@1|root,COG2226@2|Bacteria,1NNRW@1224|Proteobacteria,1T8Z5@1236|Gammaproteobacteria,1XBFC@135614|Xanthomonadales	135614|Xanthomonadales	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
DPH1_k127_375912_0	861299.J421_0848	6.505e-86	302.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
DPH1_k127_375912_6	234267.Acid_6626	2.301e-05	49.0	COG0500@1|root,COG2226@2|Bacteria,3Y58M@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DPH1_k127_3765977_1	436308.Nmar_1073	1.747e-50	208.0	COG3794@1|root,arCOG05978@1|root,arCOG07813@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea,arCOG07813@2157|Archaea	2157|Archaea	C	LamG domain protein jellyroll fold domain protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	Copper-bind,GSDH,Laminin_G_3,ThuA,fn3
DPH1_k127_3765977_0	1123252.ATZF01000027_gene1612	1.457e-80	306.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DPH1_k127_3765977_2	324602.Caur_1238	5.725e-07	60.0	COG2823@1|root,COG5297@1|root,COG2823@2|Bacteria,COG5297@2|Bacteria,2GA85@200795|Chloroflexi,376AG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_378638_1	1487923.DP73_04955	4.474e-33	136.0	COG0467@1|root,COG0467@2|Bacteria,1TSIM@1239|Firmicutes,24DRY@186801|Clostridia,260SN@186807|Peptococcaceae	186801|Clostridia	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
DPH1_k127_378638_0	693661.Arcve_1631	8.812e-70	252.0	COG0467@1|root,COG2229@1|root,arCOG00362@2157|Archaea,arCOG01171@2157|Archaea,2XXH5@28890|Euryarchaeota	28890|Euryarchaeota	T	small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATPase,Arf,Robl_LC7
DPH1_k127_378638_2	415426.Hbut_0418	8.053e-08	63.0	COG0467@1|root,arCOG01171@2157|Archaea,2XPNC@28889|Crenarchaeota	28889|Crenarchaeota	T	Belongs to the UPF0273 family	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_382966_1	880073.Calab_2183	1.514e-22	115.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Calx-beta,DUF5122,Haemagg_act,HemolysinCabind,PPC,VCBS
DPH1_k127_382966_0	1408433.JHXV01000002_gene442	1.83e-95	346.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DPH1_k127_384902_0	439481.Aboo_0956	1.033e-45	176.0	COG0164@1|root,arCOG04121@2157|Archaea,2XWYC@28890|Euryarchaeota,3F2N8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DPH1_k127_384902_2	263820.PTO0559	1.263e-10	66.0	COG3255@1|root,arCOG01843@2157|Archaea,2Y0F9@28890|Euryarchaeota,241WX@183967|Thermoplasmata	183967|Thermoplasmata	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
DPH1_k127_384902_1	309801.trd_1708	7.078e-15	77.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
DPH1_k127_384902_3	1121459.AQXE01000001_gene2877	2.824e-08	62.0	2BTXB@1|root,32P5F@2|Bacteria,1Q42W@1224|Proteobacteria,439WH@68525|delta/epsilon subdivisions,2XA0S@28221|Deltaproteobacteria,2MC3G@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
DPH1_k127_3864822_4	1229203.KI301992_gene132	1.576e-53	203.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,3UWPT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
DPH1_k127_3864822_6	1278073.MYSTI_03161	5.247e-06	61.0	COG2885@1|root,COG2931@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42T9J@68525|delta/epsilon subdivisions,2WU7T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MQ	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
DPH1_k127_3864822_7	67373.JOBF01000007_gene2414	0.0006424	50.0	COG2021@1|root,COG2021@2|Bacteria,2I36C@201174|Actinobacteria	201174|Actinobacteria	E	Alpha beta hydrolase	pcaD	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
DPH1_k127_3864822_2	1382306.JNIM01000001_gene2829	1.346e-74	265.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N,Peptidase_S8
DPH1_k127_3864822_5	348780.NP_2480A	5.573e-48	196.0	COG4948@1|root,arCOG01168@2157|Archaea,2XUAK@28890|Euryarchaeota,23S9R@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DPH1_k127_3864822_1	439481.Aboo_1435	1.548e-149	490.0	COG0174@1|root,arCOG01909@2157|Archaea,2XSYS@28890|Euryarchaeota,3F33N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DPH1_k127_3864822_3	243231.GSU0751	2.616e-58	208.0	COG5423@1|root,COG5423@2|Bacteria,1N9C0@1224|Proteobacteria,42W42@68525|delta/epsilon subdivisions,2WR81@28221|Deltaproteobacteria,43TPZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
DPH1_k127_3864822_0	1236689.MMALV_12140	9.54e-270	851.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,3F2MC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DPH1_k127_3882689_1	742738.HMPREF9460_03352	2.725e-119	393.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,26804@186813|unclassified Clostridiales	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DPH1_k127_3882689_0	635013.TherJR_2732	2.347e-185	595.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DPH1_k127_3947791_0	220341.16505249	2.433e-16	93.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,3ZJZS@590|Salmonella	1236|Gammaproteobacteria	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,VCBS
DPH1_k127_395392_0	457398.HMPREF0326_01887	8.371e-60	215.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2MAZS@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
DPH1_k127_395392_1	439481.Aboo_0002	8.337e-33	139.0	COG0681@1|root,arCOG01739@2157|Archaea,2Y6XH@28890|Euryarchaeota,3F2QN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
DPH1_k127_3963721_0	673860.AciM339_1019	2.405e-203	643.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,3F2GK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	tRNA-splicing ligase RtcB	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
DPH1_k127_3963721_1	1047013.AQSP01000117_gene640	1.33e-54	206.0	COG1373@1|root,COG1373@2|Bacteria,2NQPG@2323|unclassified Bacteria	2|Bacteria	S	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DPH1_k127_3964811_0	1120949.KB903357_gene4768	8.74e-77	265.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4D8QU@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_3964811_2	797209.ZOD2009_10725	1.224e-18	98.0	arCOG08617@1|root,arCOG08617@2157|Archaea,2XW39@28890|Euryarchaeota,23SYN@183963|Halobacteria	183963|Halobacteria	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DPH1_k127_3964811_1	643648.Slip_1398	6.264e-23	104.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DPH1_k127_4016187_3	765912.Thimo_1752	2.046e-16	90.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1RZ6G@1236|Gammaproteobacteria,1X1H2@135613|Chromatiales	135613|Chromatiales	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_4016187_1	383372.Rcas_3603	8.475e-32	131.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
DPH1_k127_4016187_2	351160.LRC375	1.558e-20	103.0	arCOG02346@1|root,arCOG03799@1|root,arCOG06940@1|root,arCOG02346@2157|Archaea,arCOG03799@2157|Archaea,arCOG06940@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Anticodon_1,DUF835,GAF_2,GAF_3,HAMP,HATPase_c,PAS,PAS_3,PAS_9,Response_reg,zinc_ribbon_2
DPH1_k127_4016187_4	765420.OSCT_0225	9.953e-08	61.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,HTH_8,Sigma54_activat,V4R,XylR_N
DPH1_k127_4016187_5	511051.CSE_09290	8.761e-07	60.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
DPH1_k127_4016187_0	1123371.ATXH01000033_gene427	3.724e-96	333.0	COG1004@1|root,COG1004@2|Bacteria,2GGQN@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DPH1_k127_402808_8	118161.KB235922_gene3252	2.815e-08	59.0	COG2823@1|root,COG2885@1|root,COG2823@2|Bacteria,COG2885@2|Bacteria,1G2YF@1117|Cyanobacteria,3VIP9@52604|Pleurocapsales	1117|Cyanobacteria	M	peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	BON,OmpA
DPH1_k127_402808_1	717606.PaecuDRAFT_2033	1.221e-84	316.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_402808_5	246197.MXAN_7458	8.813e-21	109.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K07114,ko:K07169,ko:K12065	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3,3.A.7.11.1	-	-	-
DPH1_k127_402808_6	244447.XP_008327204.1	1.079e-17	97.0	KOG0613@1|root,KOG3510@1|root,KOG4222@1|root,KOG0613@2759|Eukaryota,KOG3510@2759|Eukaryota,KOG4222@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata	33208|Metazoa	T	Titin-like	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
DPH1_k127_402808_7	324602.Caur_1238	5.205e-10	72.0	COG2823@1|root,COG5297@1|root,COG2823@2|Bacteria,COG5297@2|Bacteria,2GA85@200795|Chloroflexi,376AG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_402808_9	1125971.ASJB01000045_gene3917	2.293e-05	56.0	COG0454@1|root,COG0454@2|Bacteria,2I3BJ@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_9
DPH1_k127_402808_3	589924.Ferp_1929	8.133e-34	140.0	COG1968@1|root,arCOG04761@2157|Archaea,2XTYX@28890|Euryarchaeota	28890|Euryarchaeota	I	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DPH1_k127_402808_4	195522.BD01_0344	2.96e-29	130.0	COG1437@1|root,arCOG01723@2157|Archaea,2XYQS@28890|Euryarchaeota,2440H@183968|Thermococci	183968|Thermococci	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
DPH1_k127_402808_10	351160.RCIX1229	5.426e-05	53.0	COG0716@1|root,arCOG00519@2157|Archaea	2157|Archaea	C	Flavodoxin	-	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_3
DPH1_k127_402808_0	439481.Aboo_1162	4.897e-134	442.0	COG0015@1|root,arCOG01747@2157|Archaea,2XUQ5@28890|Euryarchaeota,3F2GT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
DPH1_k127_402808_2	868131.MSWAN_2212	1.727e-36	143.0	COG1985@1|root,arCOG01489@2157|Archaea,2Y3MD@28890|Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
DPH1_k127_4049283_2	386456.JQKN01000008_gene1391	2.563e-40	154.0	COG0419@1|root,arCOG00368@2157|Archaea,2XTC7@28890|Euryarchaeota	28890|Euryarchaeota	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex	rad50	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_21,AAA_23,Rad50_zn_hook,SMC_N
DPH1_k127_4049283_1	562970.Btus_3137	1.321e-62	231.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4HFM3@91061|Bacilli,2781W@186823|Alicyclobacillaceae	91061|Bacilli	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DPH1_k127_4049283_0	1173020.Cha6605_3384	2.699e-165	531.0	COG0504@1|root,COG0504@2|Bacteria,1G0ET@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DPH1_k127_4098311_1	673860.AciM339_1211	2.042e-35	147.0	COG1361@1|root,arCOG02079@2157|Archaea,2Y6ZQ@28890|Euryarchaeota,3F30V@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4098311_0	439481.Aboo_0661	4.679e-39	156.0	COG0644@1|root,arCOG00570@2157|Archaea,2XUI9@28890|Euryarchaeota,3F2N1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	geranylgeranyl reductase	bchP	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3,HI0933_like
DPH1_k127_4127923_0	1054217.TALC_00034	2.255e-122	400.0	COG0519@1|root,arCOG00085@2157|Archaea,2XT82@28890|Euryarchaeota,241KI@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the synthesis of GMP from XMP	guaAB	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GMP_synt_C,NAD_synthase
DPH1_k127_4127923_4	387631.Asulf_00165	1.567e-25	124.0	COG0794@1|root,arCOG00068@2157|Archaea,2XX86@28890|Euryarchaeota,2464Z@183980|Archaeoglobi	183980|Archaeoglobi	M	PFAM Sugar isomerase (SIS)	-	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
DPH1_k127_4127923_1	673860.AciM339_0397	1.235e-96	328.0	COG0648@1|root,arCOG01894@2157|Archaea,2XU62@28890|Euryarchaeota,3F2J1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
DPH1_k127_4127923_3	673860.AciM339_0341	1.352e-36	151.0	COG1608@1|root,arCOG00860@2157|Archaea,2XSUI@28890|Euryarchaeota,3F2MV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids	argB1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DPH1_k127_4127923_2	485913.Krac_11901	3.536e-53	209.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
DPH1_k127_4142257_0	439481.Aboo_1190	1.126e-21	102.0	COG3815@1|root,arCOG03949@2157|Archaea,2Y6YC@28890|Euryarchaeota,3F307@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
DPH1_k127_4142257_1	1120958.AULD01000005_gene1946	0.0004221	50.0	2DSXT@1|root,32UTZ@2|Bacteria,2GKR7@201174|Actinobacteria,4FK4Z@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
DPH1_k127_4174884_4	1118054.CAGW01000089_gene3463	2.261e-27	129.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes,4HCR1@91061|Bacilli,27690@186822|Paenibacillaceae	91061|Bacilli	S	Peptidase family M28	ywaD	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28
DPH1_k127_4174884_3	1347392.CCEZ01000015_gene2772	1.907e-28	125.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,36FKV@31979|Clostridiaceae	186801|Clostridia	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DPH1_k127_4174884_1	269797.Mbar_A3266	6.084e-39	159.0	COG0778@1|root,arCOG00288@2157|Archaea,2Y6YN@28890|Euryarchaeota,2NB04@224756|Methanomicrobia	224756|Methanomicrobia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_4174884_5	357808.RoseRS_1151	8.092e-27	119.0	COG1011@1|root,COG1011@2|Bacteria,2G73G@200795|Chloroflexi,3760J@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
DPH1_k127_4174884_2	1094980.Mpsy_1303	8.577e-35	139.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2N9YG@224756|Methanomicrobia	224756|Methanomicrobia	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DPH1_k127_4174884_0	234267.Acid_5088	3.765e-207	655.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DPH1_k127_4182093_1	756272.Plabr_3976	1.649e-17	88.0	COG0576@1|root,COG0576@2|Bacteria,2J0MS@203682|Planctomycetes	203682|Planctomycetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DPH1_k127_4182093_0	477974.Daud_2057	5.164e-244	767.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,260NN@186807|Peptococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DPH1_k127_4257900_2	744872.Spica_2207	1.651e-11	66.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria	2|Bacteria	L	Protein of unknown function (DUF1722)	ybgA	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
DPH1_k127_4257900_0	555079.Toce_0464	1.33e-68	248.0	COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,24F1Y@186801|Clostridia,42G35@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
DPH1_k127_4257900_1	880073.Calab_2841	2.045e-15	86.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
DPH1_k127_428586_1	673860.AciM339_1477	2.795e-71	260.0	COG2047@1|root,arCOG00348@2157|Archaea,2XSX4@28890|Euryarchaeota,3F2K5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
DPH1_k127_428586_4	529709.PYCH_04040	1.649e-07	63.0	COG2260@1|root,arCOG00906@2157|Archaea,2Y1HX@28890|Euryarchaeota,244PG@183968|Thermococci	183968|Thermococci	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
DPH1_k127_428586_0	439481.Aboo_1152	4.151e-82	280.0	COG1093@1|root,arCOG04107@2157|Archaea,2XTV0@28890|Euryarchaeota,3F2GS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2a	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
DPH1_k127_428586_3	456442.Mboo_1952	1.301e-11	73.0	COG2051@1|root,arCOG04108@2157|Archaea,2XZW2@28890|Euryarchaeota,2NA0J@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM Ribosomal protein S27E	rps27e	-	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
DPH1_k127_428586_2	439481.Aboo_1154	2.65e-38	145.0	COG1631@1|root,arCOG04109@2157|Archaea,2XXV3@28890|Euryarchaeota,3F2Q7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl44e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
DPH1_k127_4298168_2	649764.HMPREF0762_00780	0.0006253	47.0	COG2332@1|root,COG2332@2|Bacteria,2HUFT@201174|Actinobacteria,4CUH1@84998|Coriobacteriia	84998|Coriobacteriia	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
DPH1_k127_4298168_0	593117.TGAM_1945	1.077e-17	94.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWJA@28890|Euryarchaeota,243ZM@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_4298168_1	635013.TherJR_2595	2.955e-17	97.0	COG3303@1|root,COG3303@2|Bacteria,1VQ4R@1239|Firmicutes,24VCY@186801|Clostridia,265U5@186807|Peptococcaceae	186801|Clostridia	P	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554
DPH1_k127_4311805_1	368407.Memar_1117	2.032e-59	212.0	COG3382@1|root,arCOG04250@2157|Archaea,2Y2KD@28890|Euryarchaeota,2NAIE@224756|Methanomicrobia	224756|Methanomicrobia	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
DPH1_k127_4311805_0	944480.ATUV01000001_gene602	1.245e-182	584.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria	1224|Proteobacteria	Q	4-hydroxyphenylacetate	-	-	-	-	-	-	-	-	-	-	-	-	HpaB,HpaB_N
DPH1_k127_4317262_1	673860.AciM339_0236	8.705e-40	157.0	COG1056@1|root,arCOG00972@2157|Archaea,2XUF7@28890|Euryarchaeota,3F2N0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Cytidylyltransferase-like	nadM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DPH1_k127_4317262_0	673860.AciM339_1547	1.548e-242	766.0	COG0466@1|root,arCOG02160@2157|Archaea,2XTT0@28890|Euryarchaeota,3F2HW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Belongs to the peptidase S16 family	lon	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
DPH1_k127_4324015_1	1298863.AUEP01000001_gene908	2.002e-19	105.0	COG1629@1|root,COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG4771@2|Bacteria,COG5297@2|Bacteria,2I7N8@201174|Actinobacteria	201174|Actinobacteria	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4324015_0	644966.Tmar_1048	1.005e-66	239.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WCDK@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_4387900_4	436308.Nmar_1073	3.673e-48	200.0	COG3794@1|root,arCOG05978@1|root,arCOG07813@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea,arCOG07813@2157|Archaea	2157|Archaea	C	LamG domain protein jellyroll fold domain protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	Copper-bind,GSDH,Laminin_G_3,ThuA,fn3
DPH1_k127_4387900_1	717606.PaecuDRAFT_2033	1.951e-91	341.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_4387900_3	479434.Sthe_1936	1.403e-54	199.0	COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi,27Y7D@189775|Thermomicrobia	189775|Thermomicrobia	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
DPH1_k127_4387900_2	647113.Metok_0799	5.733e-79	272.0	COG0152@1|root,arCOG04421@2157|Archaea,2XUKC@28890|Euryarchaeota,23Q1A@183939|Methanococci	183939|Methanococci	F	PFAM SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DPH1_k127_4387900_5	439481.Aboo_0646	2.38e-19	94.0	COG1522@1|root,arCOG01580@2157|Archaea,2Y746@28890|Euryarchaeota,3F3D8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_4387900_6	673860.AciM339_0164	1.72e-12	68.0	arCOG05368@1|root,arCOG05368@2157|Archaea,2Y1EG@28890|Euryarchaeota,3F2W6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4387900_0	351160.RCIX501	2.146e-107	363.0	COG0446@1|root,arCOG01069@2157|Archaea,2XT0A@28890|Euryarchaeota,2N97N@224756|Methanomicrobia	224756|Methanomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	ndh	-	1.6.3.3	ko:K17870	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
DPH1_k127_4387900_7	1121405.dsmv_3277	1.07e-08	56.0	2E32K@1|root,32Y2U@2|Bacteria,1N8SE@1224|Proteobacteria,42WC1@68525|delta/epsilon subdivisions,2WS7P@28221|Deltaproteobacteria,2MNVF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4405347_1	1123508.JH636447_gene7923	2.572e-11	79.0	COG1657@1|root,COG1657@2|Bacteria,2IZ5Q@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
DPH1_k127_4405347_0	720554.Clocl_2107	2.867e-12	83.0	COG1305@1|root,COG1305@2|Bacteria,1UVFG@1239|Firmicutes,2496A@186801|Clostridia,3WIAW@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,Transglut_core
DPH1_k127_4405347_2	1416752.AYME01000012_gene1036	1.941e-06	61.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_4419818_0	760568.Desku_2121	8.539e-91	316.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,2609U@186807|Peptococcaceae	186801|Clostridia	E	Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
DPH1_k127_4419818_1	247490.KSU1_C1240	2.178e-65	234.0	COG1924@1|root,COG1924@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DPH1_k127_442741_2	698757.Pogu_2279	2.856e-26	123.0	COG0477@1|root,arCOG00130@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DPH1_k127_442741_3	1089551.KE386572_gene1743	7.88e-15	84.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria,4BRG6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_442741_0	706587.Desti_3910	9.131e-69	246.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DPH1_k127_442741_1	706587.Desti_3909	1.634e-28	123.0	COG0524@1|root,COG0524@2|Bacteria,1Q29R@1224|Proteobacteria,43F2W@68525|delta/epsilon subdivisions,2X369@28221|Deltaproteobacteria,2MS4I@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DPH1_k127_4428260_1	634497.HAH_1990	6.225e-07	61.0	COG4083@1|root,arCOG04471@2157|Archaea,2XTQZ@28890|Euryarchaeota,23TMZ@183963|Halobacteria	183963|Halobacteria	S	Membrane	artA	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
DPH1_k127_4428260_0	1284352.AOIG01000013_gene3550	3.338e-39	169.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
DPH1_k127_4428260_2	745718.JADT01000017_gene1033	2.308e-05	58.0	COG5276@1|root,COG5276@2|Bacteria,4NPJY@976|Bacteroidetes,1I2K9@117743|Flavobacteriia	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SusE,fn3
DPH1_k127_444987_0	1313172.YM304_36720	7.654e-07	62.0	COG2931@1|root,COG5184@1|root,COG2931@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,RCC1,RCC1_2,VCBS
DPH1_k127_444987_1	483219.LILAB_26110	1.506e-05	47.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	1.1.98.6	ko:K03676,ko:K06191,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000,ko03110	-	-	-	ATP-cone,Glutaredoxin,NRDD
DPH1_k127_4458514_3	880073.Calab_0674	1.49e-08	68.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
DPH1_k127_4458514_1	224719.Abm4_0045	1.512e-13	77.0	arCOG07681@1|root,arCOG07681@2157|Archaea,2Y5MU@28890|Euryarchaeota	28890|Euryarchaeota	S	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
DPH1_k127_4458514_0	1054217.TALC_00899	1.255e-78	274.0	COG2144@1|root,arCOG00640@2157|Archaea,2XTU9@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM AIR synthase related protein	-	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DPH1_k127_4458514_4	1210908.HSB1_29920	9.791e-05	50.0	arCOG03232@1|root,arCOG03232@2157|Archaea,2Y0EC@28890|Euryarchaeota,23Y9D@183963|Halobacteria	183963|Halobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
DPH1_k127_4458514_2	460265.Mnod_1454	8.194e-10	63.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2TSK5@28211|Alphaproteobacteria,1JS9V@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DPH1_k127_4469054_6	1123393.KB891326_gene172	0.0001756	51.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria,1KSU9@119069|Hydrogenophilales	119069|Hydrogenophilales	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4469054_1	768066.HELO_3578	7.804e-47	177.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,1XJCR@135619|Oceanospirillales	135619|Oceanospirillales	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DPH1_k127_4469054_3	401053.AciPR4_2332	2.812e-35	155.0	COG2374@1|root,COG4932@1|root,COG5276@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,3Y8ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
DPH1_k127_4469054_5	673860.AciM339_0905	1.241e-13	75.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DPH1_k127_4469054_4	1144275.COCOR_06089	5.499e-18	99.0	COG2885@1|root,COG4733@1|root,COG2885@2|Bacteria,COG4733@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
DPH1_k127_4469054_0	439481.Aboo_0589	4.098e-114	379.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F38N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DPH1_k127_4469054_2	439481.Aboo_0790	1.082e-41	166.0	COG1938@1|root,arCOG00347@2157|Archaea,2XT93@28890|Euryarchaeota,3F2T7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
DPH1_k127_4474558_5	1121423.JONT01000008_gene701	1.082e-64	232.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes	1239|Firmicutes	C	binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
DPH1_k127_4474558_7	877455.Metbo_0010	1.156e-18	90.0	COG3350@1|root,arCOG04507@2157|Archaea,2Y15C@28890|Euryarchaeota	28890|Euryarchaeota	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
DPH1_k127_4474558_6	192952.MM_1902	2.358e-50	185.0	COG1247@1|root,arCOG00830@2157|Archaea,2XXA1@28890|Euryarchaeota,2NAY3@224756|Methanomicrobia	224756|Methanomicrobia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
DPH1_k127_4474558_11	357804.Ping_0248	1.291e-05	58.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743	-	ko:K13732,ko:K13733	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Collagen_bind,Gram_pos_anchor,HemolysinCabind,MucBP,SdrG_C_C,YSIRK_signal
DPH1_k127_4474558_4	523850.TON_0846	1.665e-74	260.0	COG0672@1|root,arCOG04330@2157|Archaea,2XU9A@28890|Euryarchaeota,243FI@183968|Thermococci	183968|Thermococci	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
DPH1_k127_4474558_12	1112274.KI911560_gene2245	0.0001423	53.0	COG2510@1|root,COG2510@2|Bacteria,1RJ4E@1224|Proteobacteria,2VS3K@28216|Betaproteobacteria,2KNB8@206350|Nitrosomonadales	206350|Nitrosomonadales	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
DPH1_k127_4474558_2	1121405.dsmv_1159	1.369e-78	277.0	COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,43DQS@68525|delta/epsilon subdivisions,2X6WA@28221|Deltaproteobacteria,2MID9@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
DPH1_k127_4474558_0	926569.ANT_30560	1.739e-138	462.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
DPH1_k127_4474558_3	1382356.JQMP01000003_gene1745	2.077e-78	277.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi,27YZ2@189775|Thermomicrobia	189775|Thermomicrobia	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DPH1_k127_4474558_9	589924.Ferp_0979	1.015e-08	66.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,246C7@183980|Archaeoglobi	183980|Archaeoglobi	V	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DPH1_k127_4474558_8	1216976.AX27061_3298	1.261e-15	89.0	COG0477@1|root,COG2814@2|Bacteria,1R3YS@1224|Proteobacteria,2VN82@28216|Betaproteobacteria,3T724@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DPH1_k127_4474558_1	944481.JAFP01000001_gene1601	9.941e-94	315.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria,2M691@213113|Desulfurellales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DPH1_k127_447974_2	545695.TREAZ_2782	1.323e-41	156.0	COG2309@1|root,COG2309@2|Bacteria,2J605@203691|Spirochaetes	203691|Spirochaetes	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
DPH1_k127_447974_3	316067.Geob_0814	1.907e-12	79.0	COG1361@1|root,COG1520@1|root,COG1657@1|root,COG4257@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1657@2|Bacteria,COG4257@2|Bacteria,COG4733@2|Bacteria,1QYWJ@1224|Proteobacteria,43CDC@68525|delta/epsilon subdivisions,2X7P6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_447974_4	439481.Aboo_0010	1.42e-10	75.0	COG1361@1|root,COG1572@1|root,arCOG01917@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG02532@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
DPH1_k127_447974_0	991905.SL003B_3564	3.876e-148	515.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria,4BRG6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_447974_1	673860.AciM339_1466	2.045e-53	196.0	COG0284@1|root,arCOG00081@2157|Archaea,2XU66@28890|Euryarchaeota,3F2M4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0060	OMPdecase
DPH1_k127_450469_0	452637.Oter_1254	5.911e-140	451.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
DPH1_k127_450469_3	402777.KB235903_gene647	1.654e-24	105.0	COG2361@1|root,COG2361@2|Bacteria,1G7XA@1117|Cyanobacteria,1HCYZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
DPH1_k127_450469_2	324602.Caur_2099	7.326e-30	126.0	COG1669@1|root,COG1669@2|Bacteria,2G76P@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA polymerase, beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
DPH1_k127_450469_1	1173024.KI912149_gene6263	1.548e-92	315.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1GKR9@1117|Cyanobacteria,1JMKR@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DPH1_k127_450469_4	519442.Huta_2938	9.194e-10	67.0	COG5340@1|root,arCOG04793@2157|Archaea,2XVVB@28890|Euryarchaeota,23UHQ@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
DPH1_k127_4531138_0	483219.LILAB_35455	9.411e-33	146.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,TSP_3
DPH1_k127_4531138_3	439481.Aboo_0347	1.153e-05	58.0	arCOG02170@1|root,arCOG02170@2157|Archaea,2Y6ZT@28890|Euryarchaeota,3F310@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
DPH1_k127_4531138_2	309800.C498_06128	3.458e-13	83.0	arCOG01314@1|root,arCOG01314@2157|Archaea,2XVNC@28890|Euryarchaeota,23TF3@183963|Halobacteria	183963|Halobacteria	L	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
DPH1_k127_4531138_1	1410666.JHXG01000003_gene1225	1.569e-18	99.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DPH1_k127_4542291_1	391625.PPSIR1_35507	1.731e-39	152.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
DPH1_k127_4542291_0	118173.KB235914_gene4095	2.43e-43	173.0	COG0501@1|root,COG0501@2|Bacteria,1G16J@1117|Cyanobacteria,1H9Q8@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
DPH1_k127_4545024_3	1348583.ATLH01000017_gene2670	3.716e-28	130.0	COG3291@1|root,COG3291@2|Bacteria,4PKJH@976|Bacteroidetes,1IJAY@117743|Flavobacteriia,1FAMT@104264|Cellulophaga	976|Bacteroidetes	E	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PKD
DPH1_k127_4545024_5	192952.MM_1508	2.371e-15	86.0	arCOG02911@1|root,arCOG02911@2157|Archaea,2Y0M6@28890|Euryarchaeota,2N9ZD@224756|Methanomicrobia	224756|Methanomicrobia	U	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4545024_0	439481.Aboo_0009	7.483e-188	604.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,3F2TI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DPH1_k127_4545024_1	439481.Aboo_0007	7.049e-61	223.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,3F36C@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DPH1_k127_4545024_2	439481.Aboo_0008	7.893e-56	207.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,3F37F@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DPH1_k127_4545024_4	1324957.K933_05011	8.771e-27	127.0	COG3534@1|root,arCOG10185@2157|Archaea,2XVXP@28890|Euryarchaeota,23USN@183963|Halobacteria	183963|Halobacteria	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C
DPH1_k127_4575464_11	272563.CD630_03960	0.0006531	44.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,25R3G@186804|Peptostreptococcaceae	186801|Clostridia	I	R-phenyllactate dehydratase activator	fldI	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DPH1_k127_4575464_9	1463934.JOCF01000035_gene2420	4.828e-05	56.0	COG4409@1|root,COG4409@2|Bacteria,2ID1A@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4575464_6	411464.DESPIG_01024	3.943e-16	89.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2M86G@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DPH1_k127_4575464_2	679926.Mpet_0519	7.143e-81	284.0	COG2100@1|root,arCOG00951@2157|Archaea	2157|Archaea	S	SMART Elongator protein 3 MiaB NifB	-	-	2.1.1.192	ko:K06935,ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
DPH1_k127_4575464_8	593907.Celgi_0669	3.45e-09	70.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4F0U1@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
DPH1_k127_4575464_3	1236689.MMALV_05600	6.411e-74	255.0	COG1709@1|root,arCOG04060@2157|Archaea,2XT58@28890|Euryarchaeota,3F2M5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07731	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3,HTH_31
DPH1_k127_4575464_0	243232.MJ_1546	3.889e-140	454.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23Q7Q@183939|Methanococci	183939|Methanococci	I	Belongs to the UPF0219 family	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,HMG_CoA_synt_N
DPH1_k127_4575464_1	192952.MM_0870	5.343e-128	422.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
DPH1_k127_4575464_4	673860.AciM339_0716	6.094e-36	154.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,3F2RZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	DUF35 OB-fold domain, acyl-CoA-associated	acaC	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DPH1_k127_4575464_7	1054217.TALC_01337	3.968e-15	79.0	COG4004@1|root,arCOG04412@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4575464_10	338966.Ppro_3330	0.0001408	50.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,42T06@68525|delta/epsilon subdivisions,2WWM4@28221|Deltaproteobacteria,43UKV@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DPH1_k127_4575464_5	1041930.Mtc_0367	5.57e-27	119.0	COG1926@1|root,arCOG00041@2157|Archaea,2XWHP@28890|Euryarchaeota,2N9V9@224756|Methanomicrobia	224756|Methanomicrobia	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
DPH1_k127_4642966_4	589924.Ferp_0134	5.591e-24	109.0	COG3413@1|root,arCOG02271@2157|Archaea,2XU8X@28890|Euryarchaeota	28890|Euryarchaeota	K	Bacterio-opsin activator HTH domain-containing protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
DPH1_k127_4642966_2	1094980.Mpsy_1158	7.219e-55	205.0	COG0122@1|root,arCOG00464@2157|Archaea,2XU5Y@28890|Euryarchaeota,2N9M2@224756|Methanomicrobia	224756|Methanomicrobia	L	8-oxoguanine DNA glycosylase domain protein	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
DPH1_k127_4642966_6	1123386.AUIW01000012_gene2080	1.495e-07	60.0	COG1917@1|root,COG1917@2|Bacteria,1WJWS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DPH1_k127_4642966_5	1121413.JMKT01000009_gene1999	6.134e-21	96.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MDCB@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
DPH1_k127_4642966_3	747365.Thena_1618	3.286e-30	124.0	COG4802@1|root,COG4802@2|Bacteria	2|Bacteria	C	ferredoxin-thioredoxin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B,Rhodanese
DPH1_k127_4642966_1	218284.CCDN010000001_gene27	3.322e-69	243.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
DPH1_k127_4642966_0	1121335.Clst_2624	1.975e-296	931.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,3WGZ6@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
DPH1_k127_4642966_7	1121035.AUCH01000001_gene1768	3.024e-05	47.0	COG0477@1|root,COG2814@2|Bacteria,1PATR@1224|Proteobacteria,2WEDY@28216|Betaproteobacteria,2KZV7@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_4643131_6	1227453.C444_00737	0.0004082	44.0	COG0025@1|root,COG0569@1|root,arCOG01957@2157|Archaea,arCOG01961@2157|Archaea,2XT52@28890|Euryarchaeota,23SVP@183963|Halobacteria	183963|Halobacteria	P	COG0025 NhaP-type Na H and K H antiporters	kef1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
DPH1_k127_4643131_4	439481.Aboo_0715	2.442e-32	132.0	arCOG02452@1|root,arCOG02452@2157|Archaea,2Y71S@28890|Euryarchaeota,3F36K@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	COG0467 RecA-superfamily ATPases implicated in signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4643131_3	439481.Aboo_0716	5.777e-70	244.0	COG0467@1|root,arCOG01171@2157|Archaea,2XTU3@28890|Euryarchaeota,3F31P@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Rad51	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_4643131_5	224325.AF_0936	9.559e-08	63.0	COG1989@1|root,arCOG02298@2157|Archaea,2XUQP@28890|Euryarchaeota,24693@183980|Archaeoglobi	183980|Archaeoglobi	N	Peptidase A24B, FlaK domain protein	-	-	3.4.23.52	ko:K07991	-	-	-	-	ko00000,ko01000,ko01002,ko02035,ko02044	-	-	-	Arc_PepC_II,Peptidase_A24
DPH1_k127_4643131_1	673860.AciM339_0590	2.036e-149	490.0	COG0269@1|root,arCOG00053@2157|Archaea,2XV47@28890|Euryarchaeota,3F2IP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Aldolase/RraA	-	-	4.1.2.43,5.3.1.27	ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
DPH1_k127_4643131_2	1379698.RBG1_1C00001G0361	6.096e-77	276.0	COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DPH1_k127_4643131_0	1041930.Mtc_2296	4.023e-286	908.0	COG0495@1|root,arCOG00809@2157|Archaea,2XU7M@28890|Euryarchaeota,2N99R@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
DPH1_k127_4670066_3	1473546.CH76_05805	0.000184	51.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,3IXZ4@400634|Lysinibacillus	91061|Bacilli	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DPH1_k127_4670066_2	387631.Asulf_00050	7.366e-70	246.0	COG1028@1|root,arCOG01259@2157|Archaea,2XSWX@28890|Euryarchaeota,2469N@183980|Archaeoglobi	183980|Archaeoglobi	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DPH1_k127_4670066_4	694430.Natoc_1372	0.0006832	51.0	arCOG06343@1|root,arCOG06343@2157|Archaea,2XTS0@28890|Euryarchaeota,23S72@183963|Halobacteria	183963|Halobacteria	S	poly-hydroxybutyrate biosynthetic process	phaE	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
DPH1_k127_4670066_0	795797.C497_13081	8.713e-114	394.0	COG3243@1|root,arCOG06234@1|root,arCOG06234@2157|Archaea,arCOG06344@2157|Archaea,2XSZS@28890|Euryarchaeota,23SX8@183963|Halobacteria	183963|Halobacteria	I	poly(R)-hydroxyalkanoic acid synthase subunit PhaC	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,HHH_5
DPH1_k127_4670066_1	273068.TTE0544	1.222e-74	264.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,42EVN@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DPH1_k127_4700612_0	273075.Ta0724	4.384e-73	263.0	COG1373@1|root,arCOG03167@2157|Archaea	2157|Archaea	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DPH1_k127_4700612_1	1121481.AUAS01000003_gene3739	2.732e-52	213.0	COG2931@1|root,COG5184@1|root,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
DPH1_k127_4700612_3	573063.Metin_0746	2.515e-34	143.0	COG2890@1|root,arCOG00109@2157|Archaea,2XWJZ@28890|Euryarchaeota,23QUN@183939|Methanococci	183939|Methanococci	J	PFAM methyltransferase small	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,PrmA
DPH1_k127_4700612_6	224325.AF_2282	6.518e-05	54.0	COG0202@1|root,arCOG04241@2157|Archaea,2XTQB@28890|Euryarchaeota,246MA@183980|Archaeoglobi	183980|Archaeoglobi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoD	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Fer4,RNA_pol_A_bac,RNA_pol_L
DPH1_k127_4700612_4	1380354.JIAN01000008_gene3362	4.59e-28	134.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,Malectin,PKD
DPH1_k127_4700612_7	327079.R9P9S0	9.764e-05	46.0	COG0484@1|root,KOG0714@2759|Eukaryota,38BTN@33154|Opisthokonta,3NW97@4751|Fungi,3UY1G@5204|Basidiomycota	4751|Fungi	O	DnaJ-domain-containing protein	SIS1	GO:0002181,GO:0002183,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005840,GO:0006403,GO:0006404,GO:0006412,GO:0006413,GO:0006457,GO:0006508,GO:0006511,GO:0006515,GO:0006518,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006950,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0010033,GO:0010467,GO:0010498,GO:0015031,GO:0015833,GO:0015931,GO:0015935,GO:0019538,GO:0019941,GO:0022626,GO:0022627,GO:0030163,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033554,GO:0034613,GO:0034641,GO:0034645,GO:0035719,GO:0035966,GO:0035967,GO:0042221,GO:0042886,GO:0043043,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0050657,GO:0050658,GO:0050896,GO:0051031,GO:0051082,GO:0051169,GO:0051170,GO:0051179,GO:0051234,GO:0051236,GO:0051603,GO:0051641,GO:0051649,GO:0051716,GO:0051787,GO:0051788,GO:0070727,GO:0070843,GO:0070887,GO:0071218,GO:0071310,GO:0071630,GO:0071702,GO:0071704,GO:0071705,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K09510	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,DnaJ_C
DPH1_k127_4700612_5	1041930.Mtc_1686	5.106e-08	63.0	COG2253@1|root,arCOG03839@2157|Archaea,2XWPU@28890|Euryarchaeota	28890|Euryarchaeota	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	ko:K09144	-	-	-	-	ko00000	-	-	-	AbiEii
DPH1_k127_4701190_1	1289387.AUKW01000013_gene4162	2.015e-09	68.0	COG0500@1|root,COG2226@2|Bacteria,2I35J@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DPH1_k127_4701190_0	272557.APE_2578	3.894e-31	130.0	COG0842@1|root,arCOG01467@2157|Archaea,2XQF4@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DPH1_k127_4716841_0	1236689.MMALV_00300	8.169e-73	259.0	COG1676@1|root,arCOG01701@2157|Archaea,2XTKB@28890|Euryarchaeota,3F2U2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	tRNA intron endonuclease, catalytic C-terminal domain	endA	GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
DPH1_k127_4754355_0	479434.Sthe_2481	4.4e-60	220.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Hydantoinaseoxoprolinase domain protein	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
DPH1_k127_476624_4	529709.PYCH_02380	5.91e-47	174.0	COG0674@1|root,arCOG01607@2157|Archaea,2XW4W@28890|Euryarchaeota,2434K@183968|Thermococci	183968|Thermococci	C	ferredoxin oxidoreductase, subunit alpha	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DPH1_k127_476624_1	1343739.PAP_05655	1.732e-98	334.0	COG1013@1|root,arCOG01599@2157|Archaea,2XUSE@28890|Euryarchaeota,2436C@183968|Thermococci	183968|Thermococci	C	ferredoxin oxidoreductase, subunit beta	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DPH1_k127_476624_5	523845.AQXV01000053_gene693	2.51e-31	138.0	COG1014@1|root,arCOG01602@2157|Archaea,2XUK0@28890|Euryarchaeota,23QJ8@183939|Methanococci	183939|Methanococci	C	PFAM Pyruvate	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
DPH1_k127_476624_0	2325.TKV_c19240	2.419e-195	639.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,42EZ8@68295|Thermoanaerobacterales	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,Fer4_10,POR_N,TPP_enzyme_C
DPH1_k127_476624_3	316067.Geob_2795	1.004e-50	190.0	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
DPH1_k127_476624_2	639282.DEFDS_0964	4.826e-60	213.0	COG1541@1|root,COG1541@2|Bacteria,2GEXG@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DPH1_k127_4794728_0	370438.PTH_2131	5.636e-290	903.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24BRX@186801|Clostridia,260H8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DPH1_k127_4794728_1	292459.STH1673	3.099e-69	246.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
DPH1_k127_4808216_4	1047013.AQSP01000144_gene917	1.528e-17	82.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
DPH1_k127_4808216_0	1047013.AQSP01000144_gene916	4.286e-162	522.0	COG1104@1|root,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DPH1_k127_4808216_2	1047013.AQSP01000144_gene915	4.89e-82	299.0	COG0492@1|root,COG0822@1|root,COG0492@2|Bacteria,COG0822@2|Bacteria,2NPRS@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_oxidored,FeS_assembly_P,NifU_N,Pyr_redox_2,cNMP_binding
DPH1_k127_4808216_3	523850.TON_0876	8.888e-31	134.0	arCOG07677@1|root,arCOG07677@2157|Archaea,2XWVM@28890|Euryarchaeota,244MD@183968|Thermococci	183968|Thermococci	S	Possible catecholamine-binding domain present in a variety of eukaryotic proteins.	-	-	-	-	-	-	-	-	-	-	-	-	DOMON
DPH1_k127_4808216_1	351160.RCIX79	2.48e-130	434.0	COG1249@1|root,arCOG01068@2157|Archaea,2XTJE@28890|Euryarchaeota,2N9NV@224756|Methanomicrobia	224756|Methanomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DPH1_k127_4865642_0	192952.MM_1914	1.02e-51	192.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,2N9DU@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM metallophosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DPH1_k127_4865642_2	368407.Memar_0521	3.269e-16	88.0	COG2426@1|root,arCOG01330@2157|Archaea,2Y4KG@28890|Euryarchaeota	28890|Euryarchaeota	S	Small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DPH1_k127_4865642_1	1396141.BATP01000003_gene4864	9.838e-30	138.0	COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	2|Bacteria	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	oprH	-	3.2.1.4,3.2.1.73	ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449	ko00500,ko01100,ko05133,map00500,map01100,map05133	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko02000	1.B.14,1.B.14.2,1.B.40.2	GH5,GH9	-	Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3
DPH1_k127_4881880_0	644281.MFS40622_1675	1.205e-48	186.0	COG0524@1|root,arCOG00014@2157|Archaea,2XU7Z@28890|Euryarchaeota,23QJY@183939|Methanococci	183939|Methanococci	G	Belongs to the carbohydrate kinase PfkB family	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.1.213,2.7.1.73	ko:K22026	ko00230,ko00240,map00230,map00240	-	R00513,R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DPH1_k127_4881880_1	497964.CfE428DRAFT_5247	4.763e-06	59.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
DPH1_k127_4884965_0	439235.Dalk_2289	4.776e-09	69.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
DPH1_k127_4908_6	1457250.BBMO01000002_gene2838	2.108e-12	81.0	arCOG02420@1|root,arCOG03991@1|root,arCOG02420@2157|Archaea,arCOG03991@2157|Archaea,2Y822@28890|Euryarchaeota	28890|Euryarchaeota	S	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Pilin_N
DPH1_k127_4908_2	397948.Cmaq_0743	9.03e-43	179.0	COG0163@1|root,arCOG01703@2157|Archaea,2XQJ7@28889|Crenarchaeota	28889|Crenarchaeota	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DPH1_k127_4908_5	673860.AciM339_0905	8.793e-19	91.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DPH1_k127_4908_3	673860.AciM339_0905	2.229e-23	103.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DPH1_k127_4908_1	867903.ThesuDRAFT_02027	5.088e-110	363.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3WCFU@538999|Clostridiales incertae sedis	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
DPH1_k127_4908_4	29176.XP_003881633.1	5.534e-20	96.0	COG0071@1|root,KOG0710@2759|Eukaryota,3YCB3@5794|Apicomplexa,3YM5V@5796|Coccidia,3YTY4@5809|Sarcocystidae	5794|Apicomplexa	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DPH1_k127_4908_0	673860.AciM339_0643	1.688e-309	965.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,3F39E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
DPH1_k127_4927222_1	1042877.GQS_07795	4.771e-47	176.0	COG2109@1|root,arCOG04678@2157|Archaea,2XUZ3@28890|Euryarchaeota,242IY@183968|Thermococci	183968|Thermococci	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
DPH1_k127_4927222_0	555079.Toce_1834	3.699e-236	749.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DPH1_k127_4942058_1	1121406.JAEX01000002_gene805	1.318e-57	211.0	COG1035@1|root,COG1152@1|root,COG1035@2|Bacteria,COG1152@2|Bacteria,1R4GN@1224|Proteobacteria,42P9J@68525|delta/epsilon subdivisions,2WJ9S@28221|Deltaproteobacteria,2MGKM@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_17,FrhB_FdhB_C
DPH1_k127_4942058_4	456442.Mboo_0005	4.385e-14	73.0	COG2835@1|root,arCOG04124@2157|Archaea,2XZRS@28890|Euryarchaeota,2NA4S@224756|Methanomicrobia	224756|Methanomicrobia	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
DPH1_k127_4942058_2	1382356.JQMP01000004_gene20	2.909e-42	160.0	COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi,27YEK@189775|Thermomicrobia	189775|Thermomicrobia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DPH1_k127_4942058_0	926569.ANT_14870	1.889e-255	829.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DPH1_k127_4942058_3	1122222.AXWR01000060_gene813	1.796e-35	147.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DPH1_k127_499072_0	368407.Memar_1634	3.019e-63	228.0	COG2102@1|root,arCOG00035@2157|Archaea,2XTNJ@28890|Euryarchaeota,2N9QU@224756|Methanomicrobia	224756|Methanomicrobia	E	Diphthamide synthase	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
DPH1_k127_499072_1	387631.Asulf_01695	5.155e-07	55.0	COG4068@1|root,arCOG04390@2157|Archaea	2157|Archaea	S	Uncharacterized protein containing a Zn-ribbon (DUF2116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
DPH1_k127_499139_0	1054217.TALC_01077	7.253e-127	418.0	COG0423@1|root,arCOG00405@2157|Archaea,2XSZK@28890|Euryarchaeota,241J5@183967|Thermoplasmata	183967|Thermoplasmata	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DPH1_k127_499139_2	1041930.Mtc_1235	3.576e-43	164.0	COG4800@1|root,arCOG04375@2157|Archaea,2XXJS@28890|Euryarchaeota,2N9MB@224756|Methanomicrobia	224756|Methanomicrobia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DPH1_k127_499139_3	706587.Desti_5346	1.031e-39	161.0	COG0715@1|root,COG0715@2|Bacteria,1RHDX@1224|Proteobacteria,42V6G@68525|delta/epsilon subdivisions,2WRZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	iAF987.Gmet_0996	NMT1_2
DPH1_k127_499139_4	706587.Desti_5345	1.717e-39	159.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,42SE1@68525|delta/epsilon subdivisions,2WPX3@28221|Deltaproteobacteria,2MRIM@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
DPH1_k127_499139_1	368407.Memar_0849	9.584e-84	297.0	COG1116@1|root,arCOG00193@2157|Archaea,2XT97@28890|Euryarchaeota,2N9FI@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM ABC transporter related	ssuB	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
DPH1_k127_499583_1	1296415.JACC01000002_gene3181	4.198e-11	78.0	COG3291@1|root,COG3397@1|root,COG4412@1|root,COG3291@2|Bacteria,COG3397@2|Bacteria,COG4412@2|Bacteria,4PHYH@976|Bacteroidetes,1IGDD@117743|Flavobacteriia,2YHN3@290174|Aquimarina	976|Bacteroidetes	G	Lytic polysaccharide mono-oxygenase, cellulose-degrading	-	-	-	-	-	-	-	-	-	-	-	-	LPMO_10,PKD
DPH1_k127_499583_2	765420.OSCT_1540	3.953e-05	58.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria,2G8N3@200795|Chloroflexi,3757D@32061|Chloroflexia	32061|Chloroflexia	MT	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_499583_0	926562.Oweho_0360	3.447e-20	108.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,VCBS
DPH1_k127_4998329_4	643648.Slip_1415	7.001e-34	148.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,42KB4@68298|Syntrophomonadaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DPH1_k127_4998329_0	1487921.DP68_00495	1.648e-142	464.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,36DVG@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the thiolase family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DPH1_k127_4998329_11	1266998.ATUJ01000004_gene1433	1.141e-05	57.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,2TTDM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
DPH1_k127_4998329_7	926566.Terro_1691	7.593e-09	69.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
DPH1_k127_4998329_2	644282.Deba_0614	5.923e-40	158.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
DPH1_k127_4998329_6	1267533.KB906740_gene137	4.444e-10	65.0	29Y1S@1|root,30JUQ@2|Bacteria,3Y90C@57723|Acidobacteria,2JNWN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4998329_5	410358.Mlab_1688	8.96e-29	123.0	arCOG03622@1|root,arCOG03622@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4998329_8	1541960.KQ78_01444	2.111e-08	66.0	2E6H4@1|root,3314B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_4998329_12	196162.Noca_3920	0.0009907	51.0	COG4978@1|root,COG4978@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
DPH1_k127_4998329_1	1313421.JHBV01000033_gene2422	2.452e-52	209.0	COG5587@1|root,COG5587@2|Bacteria,4NRNM@976|Bacteroidetes	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
DPH1_k127_4998329_3	1041930.Mtc_0093	5.763e-36	150.0	COG0301@1|root,arCOG00038@2157|Archaea,2XUHM@28890|Euryarchaeota,2N98H@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
DPH1_k127_4998329_9	344747.PM8797T_31438	4.914e-08	65.0	COG2268@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG4254@1|root,COG4932@1|root,COG5276@1|root,COG2268@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4254@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
DPH1_k127_5006708_0	391612.CY0110_15537	5.792e-73	267.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,1G1I0@1117|Cyanobacteria,3KK8R@43988|Cyanothece	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Lectin_C
DPH1_k127_5006708_1	1379698.RBG1_1C00001G1047	1.059e-31	131.0	COG1913@1|root,COG1913@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
DPH1_k127_5006708_2	44056.XP_009041975.1	7.648e-05	55.0	COG0459@1|root,KOG0358@2759|Eukaryota	2759|Eukaryota	O	unfolded protein binding	CCT4	GO:0000003,GO:0000166,GO:0002199,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0006403,GO:0006457,GO:0006458,GO:0006810,GO:0007275,GO:0007338,GO:0007339,GO:0008037,GO:0008144,GO:0008150,GO:0009566,GO:0009653,GO:0009791,GO:0009886,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010035,GO:0010038,GO:0010171,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0015630,GO:0017076,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0031974,GO:0031981,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0035036,GO:0035639,GO:0036094,GO:0040032,GO:0042221,GO:0043085,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044093,GO:0044183,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045935,GO:0046686,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050896,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051338,GO:0051347,GO:0051704,GO:0051972,GO:0051973,GO:0060255,GO:0060341,GO:0061077,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070202,GO:0070203,GO:0080090,GO:0090666,GO:0090670,GO:0090685,GO:0097159,GO:0097367,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:1901265,GO:1901363,GO:1901998,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904872,GO:1904874,GO:1904951,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09496,ko:K09500	-	-	-	-	ko00000,ko03036,ko03110,ko04147	-	-	-	Cpn60_TCP1
DPH1_k127_5033790_1	234267.Acid_7234	1.742e-53	209.0	COG0457@1|root,COG0457@2|Bacteria,3Y5ID@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5033790_4	1096930.L284_08345	2.64e-05	51.0	COG1522@1|root,COG1522@2|Bacteria,1RAP6@1224|Proteobacteria,2U5FX@28211|Alphaproteobacteria,2KE1U@204457|Sphingomonadales	204457|Sphingomonadales	K	AsnC family	-	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
DPH1_k127_5033790_3	1054217.TALC_00187	1.418e-13	72.0	COG1986@1|root,arCOG01221@2157|Archaea,2Y53C@28890|Euryarchaeota	28890|Euryarchaeota	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5033790_0	1457250.BBMO01000001_gene1581	2.904e-63	250.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_5033790_2	880073.Calab_1823	2.208e-17	98.0	COG0860@1|root,COG4412@1|root,COG0860@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	bpr	GO:0005575,GO:0005576	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K09955,ko:K13276	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036,ko03110	-	-	-	CHAP,CarbopepD_reg_2,CarboxypepD_reg,GBS_Bsp-like,Glyco_hydro_25,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8,SH3_5,VanY,YSIRK_signal
DPH1_k127_5066544_5	304371.MCP_2783	3.429e-43	167.0	COG2042@1|root,arCOG04733@2157|Archaea,2XVBD@28890|Euryarchaeota,2N9PH@224756|Methanomicrobia	224756|Methanomicrobia	J	pre-rRNA processing protein involved in ribosome biogenesis	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
DPH1_k127_5066544_3	273075.Ta0516m	1.849e-113	381.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,241M8@183967|Thermoplasmata	183967|Thermoplasmata	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
DPH1_k127_5066544_6	304371.MCP_0503	2.995e-13	73.0	COG1145@1|root,arCOG00958@2157|Archaea,2Y1CC@28890|Euryarchaeota,2NA30@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
DPH1_k127_5066544_1	439481.Aboo_0580	7.695e-162	527.0	COG1964@1|root,arCOG00933@2157|Archaea,2XTMK@28890|Euryarchaeota,3F2FE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Intein_splicing,LAGLIDADG_3,Radical_SAM
DPH1_k127_5066544_4	673860.AciM339_1568	7.793e-60	216.0	COG1378@1|root,arCOG02038@2157|Archaea,2Y7FZ@28890|Euryarchaeota,3F2ZR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
DPH1_k127_5066544_0	272844.PAB1172	1.78e-178	571.0	COG1003@1|root,arCOG00076@2157|Archaea,2XT3V@28890|Euryarchaeota,242MV@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
DPH1_k127_5066544_2	768706.Desor_4793	5.548e-121	403.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
DPH1_k127_5096258_8	1054217.TALC_00205	1.23e-16	91.0	COG1571@1|root,arCOG01116@2157|Archaea,2XTUY@28890|Euryarchaeota	28890|Euryarchaeota	S	methanogenesis marker protein 11	-	-	-	-	-	-	-	-	-	-	-	-	DUF1743
DPH1_k127_5096258_1	192952.MM_2300	1.055e-71	249.0	COG2220@1|root,arCOG00497@2157|Archaea,2XTCN@28890|Euryarchaeota,2N9ME@224756|Methanomicrobia	224756|Methanomicrobia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
DPH1_k127_5096258_5	224324.aq_2028	8.8e-28	118.0	COG0490@1|root,COG0490@2|Bacteria,2G45Z@200783|Aquificae	200783|Aquificae	P	TrkA-C domain protein	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
DPH1_k127_5096258_4	1500897.JQNA01000001_gene6416	1.3e-34	153.0	COG4651@1|root,COG4651@2|Bacteria,1QUQS@1224|Proteobacteria,2WH05@28216|Betaproteobacteria,1K26F@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
DPH1_k127_5096258_3	1234364.AMSF01000016_gene1615	2.465e-43	180.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1GS@1236|Gammaproteobacteria,1XDBH@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
DPH1_k127_5096258_7	264732.Moth_1410	2.405e-20	91.0	COG2768@1|root,COG2768@2|Bacteria,1UJ45@1239|Firmicutes,24W31@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
DPH1_k127_5096258_10	1193181.BN10_450002	0.0002535	46.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4FHC8@85021|Intrasporangiaceae	201174|Actinobacteria	K	AsnC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DPH1_k127_5096258_6	304371.MCP_1009	3.745e-25	110.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,2NB7P@224756|Methanomicrobia	224756|Methanomicrobia	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
DPH1_k127_5096258_2	439481.Aboo_1449	7.286e-70	243.0	COG2078@1|root,arCOG01336@2157|Archaea,2XUAP@28890|Euryarchaeota,3F2RN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
DPH1_k127_5096258_0	592015.HMPREF1705_01410	6.187e-115	390.0	COG0624@1|root,COG0624@2|Bacteria,3TAG2@508458|Synergistetes	508458|Synergistetes	E	TIGRFAM acetylornithine deacetylase or	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DPH1_k127_5096258_9	1267535.KB906767_gene2592	2.5e-06	55.0	COG0611@1|root,COG0611@2|Bacteria,3Y30U@57723|Acidobacteria,2JHT0@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DPH1_k127_5111127_2	911045.PSE_3802	6.189e-05	54.0	COG1247@1|root,COG1247@2|Bacteria,1N04H@1224|Proteobacteria,2UQB4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	YoaP
DPH1_k127_5111127_0	316274.Haur_1012	2.204e-49	194.0	COG0454@1|root,COG1246@1|root,COG0456@2|Bacteria,COG1246@2|Bacteria,2G8UQ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DPH1_k127_5126768_0	555088.DealDRAFT_0595	1.95e-143	462.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,42KZ0@68298|Syntrophomonadaceae	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DPH1_k127_5129808_1	1343739.PAP_02640	1.18e-33	141.0	arCOG07677@1|root,arCOG07677@2157|Archaea,2XWVM@28890|Euryarchaeota,244MD@183968|Thermococci	183968|Thermococci	S	Possible catecholamine-binding domain present in a variety of eukaryotic proteins.	-	-	-	-	-	-	-	-	-	-	-	-	DOMON
DPH1_k127_5129808_2	1158165.KB898872_gene1088	7.21e-17	82.0	COG3450@1|root,COG3450@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
DPH1_k127_5129808_4	1254432.SCE1572_40415	5.631e-06	58.0	COG3450@1|root,COG3450@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
DPH1_k127_5129808_0	1120951.AUBG01000012_gene1660	4.146e-37	151.0	COG3177@1|root,COG3177@2|Bacteria,4NESH@976|Bacteroidetes,1HZ51@117743|Flavobacteriia	976|Bacteroidetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
DPH1_k127_515291_0	634498.mru_0392	2.159e-126	418.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,23NP9@183925|Methanobacteria	183925|Methanobacteria	S	C-terminal region of MMR_HSR1 domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
DPH1_k127_515291_2	1278073.MYSTI_02730	5.141e-12	79.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,42TB9@68525|delta/epsilon subdivisions,2WXEF@28221|Deltaproteobacteria,2YW3Y@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
DPH1_k127_515291_1	1236689.MMALV_16740	2.868e-99	357.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,3F2IQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DEAD/H associated	lhr2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DPH1_k127_5154308_0	452637.Oter_3066	4.144e-25	125.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DctA-YdbH
DPH1_k127_5154308_1	215803.DB30_5453	6.49e-24	120.0	COG1372@1|root,COG2911@1|root,COG3209@1|root,COG3391@1|root,COG1372@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1PEID@1224|Proteobacteria,438II@68525|delta/epsilon subdivisions,2X3TD@28221|Deltaproteobacteria,2YX2B@29|Myxococcales	28221|Deltaproteobacteria	LM	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5154308_2	1226994.AMZB01000136_gene5045	3.136e-11	78.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,1YHF1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	von willebrand factor, type A	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,VCBS
DPH1_k127_5179482_0	1236689.MMALV_01850	6.932e-11	70.0	arCOG05338@1|root,arCOG05338@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_518631_0	439481.Aboo_1543	1.455e-121	403.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
DPH1_k127_518631_1	1223521.BBJX01000019_gene613	4.084e-06	56.0	COG0716@1|root,COG0716@2|Bacteria,1NANK@1224|Proteobacteria,2VW78@28216|Betaproteobacteria,4AHHR@80864|Comamonadaceae	28216|Betaproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
DPH1_k127_521289_2	744872.Spica_1727	2.625e-35	144.0	COG0095@1|root,COG0095@2|Bacteria,2J7CV@203691|Spirochaetes	203691|Spirochaetes	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
DPH1_k127_521289_1	224719.Abm4_0181	7.155e-90	321.0	COG0119@1|root,arCOG02092@2157|Archaea,2XV8D@28890|Euryarchaeota,23PFQ@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	aksA	-	2.3.3.14	ko:K10977	ko00300,ko00620,ko00680,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00620,map00680,map01100,map01120,map01130,map01210,map01230	M00608	R00271,R08213,R08331,R08332	RC00004,RC00067,RC02149,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
DPH1_k127_521289_0	1054217.TALC_01406	1.443e-112	374.0	COG0057@1|root,arCOG00493@2157|Archaea,2XT16@28890|Euryarchaeota,241JM@183967|Thermoplasmata	183967|Thermoplasmata	G	4-hydroxy-tetrahydrodipicolinate reductase	gap	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
DPH1_k127_521289_3	269797.Mbar_A1940	4.62e-12	78.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,2NAZY@224756|Methanomicrobia	224756|Methanomicrobia	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
DPH1_k127_5232369_3	469383.Cwoe_1689	0.0005556	51.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CQ7N@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
DPH1_k127_5232369_1	192952.MM_0338	1.147e-85	305.0	COG0351@1|root,arCOG00020@2157|Archaea,2XSW8@28890|Euryarchaeota,2N9G9@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
DPH1_k127_5232369_0	525904.Tter_2612	2.578e-119	404.0	COG0477@1|root,COG2814@2|Bacteria,2NQSV@2323|unclassified Bacteria	2|Bacteria	P	Fungal trichothecene efflux pump (TRI12)	mdr	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_5232369_2	635013.TherJR_1083	7.152e-57	209.0	arCOG14814@1|root,2ZC63@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5238458_1	1487923.DP73_05415	2.573e-30	131.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,261IU@186807|Peptococcaceae	186801|Clostridia	I	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DPH1_k127_5238458_0	644281.MFS40622_0126	4.573e-89	305.0	COG1775@1|root,arCOG04464@2157|Archaea	2157|Archaea	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
DPH1_k127_5238458_2	880073.Calab_2183	5.782e-07	63.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Calx-beta,DUF5122,Haemagg_act,HemolysinCabind,PPC,VCBS
DPH1_k127_5264733_0	1463895.JODA01000010_gene7153	1.977e-39	165.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria	201174|Actinobacteria	I	Squalene--hopene cyclase	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	ko:K17811	-	-	-	-	ko00000,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
DPH1_k127_5264733_1	419947.MRA_3418	1.12e-09	72.0	28XHJ@1|root,2ZJEY@2|Bacteria	2|Bacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	ko:K15911,ko:K22313	-	-	-	-	ko00000,ko01000	-	-	-	-
DPH1_k127_5264733_2	1343739.PAP_09865	4.509e-06	60.0	arCOG03797@1|root,arCOG03797@2157|Archaea,2Y8H0@28890|Euryarchaeota,24488@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
DPH1_k127_5264733_3	1121479.AUBS01000002_gene3633	0.0002133	52.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_5294757_1	69014.TK1248	7.735e-33	140.0	COG1786@1|root,arCOG04279@2157|Archaea,2XYXJ@28890|Euryarchaeota,2445F@183968|Thermococci	183968|Thermococci	C	Belongs to the UPF0107 family	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
DPH1_k127_5294757_0	1054217.TALC_00511	2.483e-112	375.0	COG1679@1|root,arCOG04278@2157|Archaea,2XTY6@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
DPH1_k127_5329218_4	1459636.NTE_01386	3.386e-06	59.0	COG0350@1|root,arCOG02724@2157|Archaea,41SR8@651137|Thaumarchaeota	651137|Thaumarchaeota	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
DPH1_k127_5329218_0	1280390.CBQR020000036_gene737	9.115e-21	101.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26XRF@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DPH1_k127_5329218_3	1128398.Curi_c00890	7.455e-07	61.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,26BUH@186813|unclassified Clostridiales	186801|Clostridia	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
DPH1_k127_5329218_1	797299.HALLA_21305	3.623e-19	101.0	arCOG04522@1|root,arCOG04522@2157|Archaea,2XTU5@28890|Euryarchaeota,23U1D@183963|Halobacteria	183963|Halobacteria	O	cytochrome c biogenesis protein	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DPH1_k127_5329218_2	3067.XP_002946103.1	1.582e-11	67.0	COG1397@1|root,2QUER@2759|Eukaryota,380MV@33090|Viridiplantae,34MGQ@3041|Chlorophyta	3041|Chlorophyta	O	ADP-ribosylglycohydrolase	-	-	3.2.1.143	ko:K11687	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
DPH1_k127_5354950_0	1236689.MMALV_10340	1.595e-156	512.0	COG0175@1|root,arCOG00073@2157|Archaea,2XUPU@28890|Euryarchaeota,3F2GA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0559	Fer4,Fer4_10,Fer4_7,PAPS_reduct,PUA
DPH1_k127_5354950_3	7668.SPU_028311-tr	1.764e-36	148.0	COG1618@1|root,2QVJ8@2759|Eukaryota,38FT1@33154|Opisthokonta,3BGUB@33208|Metazoa,3CSDG@33213|Bilateria	33208|Metazoa	O	nucleotide phosphatase activity, acting on free nucleotides	NTPCR	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
DPH1_k127_5354950_1	456442.Mboo_1987	8.411e-60	213.0	COG0301@1|root,arCOG00038@2157|Archaea,2XYMB@28890|Euryarchaeota,2NBHY@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiI
DPH1_k127_5354950_2	309801.trd_1568	3.625e-49	184.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi,27XM2@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
DPH1_k127_5377174_1	368407.Memar_1626	1.973e-112	370.0	COG0863@1|root,arCOG00115@2157|Archaea,2XWB2@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DPH1_k127_5377174_6	589924.Ferp_1587	1.494e-05	50.0	arCOG10363@1|root,arCOG10363@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5377174_0	1236689.MMALV_07230	4.84e-124	412.0	COG0520@1|root,arCOG00065@2157|Archaea,2XSYI@28890|Euryarchaeota	2157|Archaea	E	Cysteine desulfurase	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DPH1_k127_5377174_3	1047013.AQSP01000089_gene1177	3.08e-15	79.0	COG0011@1|root,COG0011@2|Bacteria,2NQ69@2323|unclassified Bacteria	2|Bacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
DPH1_k127_5377174_2	439481.Aboo_0591	1.083e-63	229.0	COG1798@1|root,arCOG04161@2157|Archaea,2XV63@28890|Euryarchaeota,3F2J0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis	dphB	GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	iAF692.Mbar_A2900	TP_methylase
DPH1_k127_5377174_4	694429.Pyrfu_1333	7.518e-12	74.0	arCOG09415@1|root,arCOG09415@2157|Archaea,2XS53@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DPH1_k127_5377174_5	1453500.AT05_07840	9.478e-09	66.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DPH1_k127_5399679_3	237368.SCABRO_03173	1.831e-90	308.0	COG0493@1|root,COG0493@2|Bacteria,2J2W6@203682|Planctomycetes	203682|Planctomycetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
DPH1_k127_5399679_0	690850.Desaf_0585	1.102e-117	401.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIWK@28221|Deltaproteobacteria,2M8CW@213115|Desulfovibrionales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05559,ko:K14086	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M,Proton_antipo_N
DPH1_k127_5399679_8	643562.Daes_2374	2.606e-60	220.0	COG0650@1|root,COG0650@2|Bacteria,1QUK1@1224|Proteobacteria,42PHN@68525|delta/epsilon subdivisions,2WKPJ@28221|Deltaproteobacteria,2M94K@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM respiratory-chain NADH dehydrogenase subunit 1	-	-	-	ko:K14087	-	-	-	-	ko00000	-	-	-	NADHdh
DPH1_k127_5399679_11	1089553.Tph_c21340	8.745e-55	211.0	COG3260@1|root,COG3260@2|Bacteria,1UHYA@1239|Firmicutes,24I1D@186801|Clostridia,42GCG@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.6.5.3	ko:K00331,ko:K14088	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DPH1_k127_5399679_19	411471.SUBVAR_06255	9.142e-07	56.0	COG0852@1|root,COG0852@2|Bacteria,1VF7W@1239|Firmicutes,24R5W@186801|Clostridia,3WMFT@541000|Ruminococcaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	ko:K14089	-	-	-	-	ko00000	-	-	-	Complex1_30kDa
DPH1_k127_5399679_1	526222.Desal_3237	2.5e-111	370.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,43DST@68525|delta/epsilon subdivisions,2WJ4E@28221|Deltaproteobacteria,2M872@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM NADH-ubiquinone oxidoreductase chain 49kDa	-	-	1.6.5.3	ko:K00333,ko:K14090	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
DPH1_k127_5399679_13	1089553.Tph_c21310	2.5e-22	108.0	COG1143@1|root,COG1143@2|Bacteria,1VDBV@1239|Firmicutes,24SHQ@186801|Clostridia,42GU6@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K14091	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4,Fer4_7
DPH1_k127_5399679_14	1408422.JHYF01000003_gene819	1.132e-21	106.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,36KWH@31979|Clostridiaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_5399679_9	416591.Tlet_1498	1.813e-57	203.0	COG2033@1|root,COG2033@2|Bacteria,2GD7N@200918|Thermotogae	200918|Thermotogae	C	Desulfoferrodoxin ferrous iron-binding	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
DPH1_k127_5399679_5	679926.Mpet_2814	3.579e-83	284.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XSXC@28890|Euryarchaeota,2N9K5@224756|Methanomicrobia	224756|Methanomicrobia	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
DPH1_k127_5399679_16	1047013.AQSP01000109_gene2440	4.446e-19	93.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
DPH1_k127_5399679_7	204669.Acid345_1869	3.63e-70	254.0	COG0577@1|root,COG0577@2|Bacteria,3Y36A@57723|Acidobacteria,2JIYT@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_5399679_6	926561.KB900623_gene833	9.341e-80	275.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_5399679_15	269799.Gmet_1554	1.178e-21	108.0	COG4393@1|root,COG4393@2|Bacteria,1R507@1224|Proteobacteria,42NQA@68525|delta/epsilon subdivisions,2WQ0C@28221|Deltaproteobacteria,43UZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
DPH1_k127_5399679_17	1459636.NTE_00644	2.375e-14	81.0	arCOG07179@1|root,arCOG07179@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5399679_10	357808.RoseRS_0015	3.547e-56	208.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi,376R3@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DPH1_k127_5399679_4	416591.Tlet_1834	2.428e-84	304.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DPH1_k127_5399679_2	688269.Theth_0193	2.186e-95	319.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_5399679_18	136993.KB900626_gene761	1.815e-08	67.0	COG2020@1|root,COG2020@2|Bacteria,1MXP9@1224|Proteobacteria,2U2A4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DPH1_k127_5399679_12	1047013.AQSP01000139_gene2368	9.657e-34	149.0	COG0730@1|root,COG0730@2|Bacteria,2NRZN@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DPH1_k127_5402282_2	269797.Mbar_A0753	3.148e-54	197.0	COG1830@1|root,arCOG04044@2157|Archaea,2XTBQ@28890|Euryarchaeota,2N93C@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	-	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DPH1_k127_5402282_3	1380390.JIAT01000010_gene4274	1.138e-17	94.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4CRMM@84995|Rubrobacteria	84995|Rubrobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DPH1_k127_5402282_0	868131.MSWAN_2165	1.344e-126	418.0	COG2327@1|root,arCOG04826@2157|Archaea	2157|Archaea	S	PFAM Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
DPH1_k127_5402282_1	868131.MSWAN_2166	9.277e-100	342.0	COG0451@1|root,COG1022@1|root,arCOG01369@2157|Archaea,arCOG04199@2157|Archaea	2157|Archaea	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,Epimerase,NAD_binding_4
DPH1_k127_5408533_0	243164.DET1501	8.8e-28	118.0	COG0716@1|root,COG0716@2|Bacteria,2GAZ4@200795|Chloroflexi,34DME@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_54340_3	351160.RCIX198	2.008e-73	255.0	COG1208@1|root,arCOG00664@2157|Archaea,2XUHB@28890|Euryarchaeota,2N995@224756|Methanomicrobia	224756|Methanomicrobia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DPH1_k127_54340_6	1144275.COCOR_04814	1.447e-46	180.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WJC2@28221|Deltaproteobacteria,2YW3A@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DPH1_k127_54340_5	760568.Desku_0717	1.566e-56	203.0	COG1898@1|root,COG1898@2|Bacteria,1V4G5@1239|Firmicutes,24IZ8@186801|Clostridia,262MP@186807|Peptococcaceae	186801|Clostridia	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
DPH1_k127_54340_0	368407.Memar_0186	6.257e-108	359.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DPH1_k127_54340_4	386456.JQKN01000003_gene387	6.693e-59	214.0	COG1083@1|root,arCOG04817@2157|Archaea	2157|Archaea	M	PFAM acylneuraminate cytidylyltransferase	neuA	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,Glyco_tran_28_C
DPH1_k127_54340_1	720554.Clocl_4180	6.278e-90	317.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,3WHC1@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylneuraminate synthase	neuB	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
DPH1_k127_54340_2	316274.Haur_4322	7.736e-84	292.0	COG0399@1|root,COG0399@2|Bacteria,2G5QG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DPH1_k127_54340_7	1227495.C487_03928	2.198e-34	147.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,23STH@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DPH1_k127_54340_8	1292034.OR37_03855	2.25e-30	123.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,2UBQS@28211|Alphaproteobacteria,2KJCS@204458|Caulobacterales	204458|Caulobacterales	S	TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	-	-	-	ko:K13006	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Hexapep
DPH1_k127_5440136_3	192952.MM_0693	1.776e-26	119.0	COG1418@1|root,arCOG01858@2157|Archaea,2XY7Y@28890|Euryarchaeota,2N9UQ@224756|Methanomicrobia	224756|Methanomicrobia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
DPH1_k127_5440136_2	673860.AciM339_0550	9.746e-43	170.0	COG1303@1|root,arCOG01857@2157|Archaea,2XV35@28890|Euryarchaeota,3F2NN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	trm56	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
DPH1_k127_5440136_1	1054217.TALC_01532	2.904e-50	184.0	COG4860@1|root,arCOG04366@2157|Archaea,2XYAX@28890|Euryarchaeota,241R5@183967|Thermoplasmata	183967|Thermoplasmata	K	ArsR transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ArsR
DPH1_k127_5440136_0	1457250.BBMO01000001_gene1581	2.289e-68	263.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_5440445_2	443254.Marpi_1007	6.39e-18	99.0	COG1520@1|root,COG1520@2|Bacteria,2GD9T@200918|Thermotogae	200918|Thermotogae	S	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5440445_3	416591.Tlet_1231	0.0003014	54.0	COG1520@1|root,COG1716@1|root,COG1520@2|Bacteria,COG1716@2|Bacteria,2GDJT@200918|Thermotogae	200918|Thermotogae	T	peptidase C11 clostripain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
DPH1_k127_5440445_0	324602.Caur_3920	8.728e-193	626.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,3756Y@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DPH1_k127_5440445_1	1041930.Mtc_1491	6.679e-57	227.0	COG0857@1|root,arCOG00099@2157|Archaea,2XU0G@28890|Euryarchaeota	28890|Euryarchaeota	C	COG0857 BioD-like N-terminal domain of phosphotransacetylase	cbiA1	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
DPH1_k127_5451108_4	1236689.MMALV_12690	2.139e-07	57.0	COG4023@1|root,arCOG02957@2157|Archaea,2Y1AH@28890|Euryarchaeota,3F2U9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	but it may be involved in stabilization of the trimeric complex	secG	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
DPH1_k127_5451108_2	589924.Ferp_0854	2.409e-85	299.0	COG0621@1|root,arCOG01358@2157|Archaea,2XSVB@28890|Euryarchaeota,2460N@183980|Archaeoglobi	183980|Archaeoglobi	J	MiaB-like tRNA modifying enzyme	-	-	2.8.4.5	ko:K15865	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DPH1_k127_5451108_3	673860.AciM339_0375	1.334e-77	270.0	COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,3F2X0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
DPH1_k127_5451108_1	673860.AciM339_0508	4.895e-147	477.0	COG0012@1|root,arCOG00357@2157|Archaea,2XTZG@28890|Euryarchaeota,3F2GD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	GTPase of unknown function C-terminal	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
DPH1_k127_5451108_0	673860.AciM339_1269	3.717e-192	617.0	COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,3F2F0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DNA polymerase type-B family	polB1	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1,Intein_splicing
DPH1_k127_5606218_3	351160.RCIX1724	8.497e-05	55.0	COG1470@1|root,arCOG02081@2157|Archaea,2Y7MM@28890|Euryarchaeota,2NASI@224756|Methanomicrobia	224756|Methanomicrobia	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
DPH1_k127_5606218_0	639282.DEFDS_1228	3.861e-237	748.0	COG4799@1|root,COG4799@2|Bacteria,2GEP0@200930|Deferribacteres	200930|Deferribacteres	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DPH1_k127_5606218_1	1123368.AUIS01000009_gene2491	4.688e-162	524.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CI	Oxaloacetate	oadA	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_5346	Biotin_lipoyl,HMGL-like,PYC_OADA
DPH1_k127_5606218_2	580340.Tlie_0406	3.21e-15	83.0	COG4770@1|root,COG4770@2|Bacteria,3TBAA@508458|Synergistetes	508458|Synergistetes	I	Biotin carboxyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
DPH1_k127_5606218_4	645512.GCWU000246_00251	0.0005941	48.0	COG0069@1|root,COG0069@2|Bacteria	2|Bacteria	E	glutamate synthase activity	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GXGXG,Glu_synthase,Rubredoxin
DPH1_k127_5620348_1	485913.Krac_12474	7.532e-29	120.0	COG1051@1|root,COG1051@2|Bacteria,2GA98@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DPH1_k127_5620348_0	342949.PNA2_1750	1.206e-44	172.0	COG0005@1|root,arCOG01327@2157|Archaea,2XUJX@28890|Euryarchaeota,242V8@183968|Thermococci	183968|Thermococci	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DPH1_k127_5641352_2	66373.JOFQ01000025_gene4510	0.0001112	51.0	COG1846@1|root,COG1846@2|Bacteria,2IM35@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
DPH1_k127_5641352_0	118168.MC7420_3051	2.239e-178	610.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DPH1_k127_5641352_1	673860.AciM339_0019	1.164e-12	82.0	COG0457@1|root,arCOG02493@1|root,arCOG02493@2157|Archaea,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	HTH_24,PQQ_2,PQQ_3,TPR_12,TPR_16,TPR_2,TPR_8
DPH1_k127_5653000_4	530564.Psta_2214	3.531e-05	57.0	COG1572@1|root,COG1572@2|Bacteria,2IYZF@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DPH1_k127_5653000_3	45351.EDO26116	1.399e-07	66.0	KOG0613@1|root,KOG0613@2759|Eukaryota	2759|Eukaryota	S	cytoskeletal protein binding	-	-	-	ko:K06768	-	-	-	-	ko00000,ko04516	-	-	-	I-set,Ig_3,fn3
DPH1_k127_5653000_1	1280390.CBQR020000166_gene4414	1.576e-41	178.0	COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase family 6	guxA	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
DPH1_k127_5653000_0	1123252.ATZF01000027_gene1612	4.247e-93	347.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DPH1_k127_5656479_3	1121405.dsmv_2612	8.911e-132	429.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2MJ2T@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DPH1_k127_5656479_0	1121405.dsmv_2611	2.569e-297	933.0	COG0603@1|root,COG1402@1|root,COG0603@2|Bacteria,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2X9RQ@28221|Deltaproteobacteria,2MPA0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
DPH1_k127_5656479_2	1121405.dsmv_2609	9.506e-140	471.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,42PSH@68525|delta/epsilon subdivisions,2WJYZ@28221|Deltaproteobacteria,2MIFM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
DPH1_k127_5656479_1	1121405.dsmv_2608	1.039e-153	494.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
DPH1_k127_5656479_7	517433.PanABDRAFT_2663	1.276e-05	60.0	COG2911@1|root,COG2911@2|Bacteria,1P8N9@1224|Proteobacteria,1T1IH@1236|Gammaproteobacteria,3VXVZ@53335|Pantoea	1236|Gammaproteobacteria	M	PFAM FecR protein	yeeJ	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3
DPH1_k127_5656479_5	426117.M446_3777	2.104e-20	104.0	COG1765@1|root,COG1765@2|Bacteria,1N1RR@1224|Proteobacteria,2UTTM@28211|Alphaproteobacteria,1JV1I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DPH1_k127_5656479_6	247490.KSU1_B0439	1.139e-05	54.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DPH1_k127_5656479_4	1071679.BG57_31840	5.045e-37	143.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,2VUWB@28216|Betaproteobacteria,1KG4W@119060|Burkholderiaceae	28216|Betaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DPH1_k127_5662631_2	693746.OBV_03430	2.193e-27	119.0	COG0500@1|root,COG2226@2|Bacteria,1UTRA@1239|Firmicutes,25401@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DPH1_k127_5662631_4	1122611.KB903971_gene2665	1.118e-16	91.0	COG1183@1|root,COG1183@2|Bacteria,2I3MV@201174|Actinobacteria,4EGBR@85012|Streptosporangiales	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pssA	GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
DPH1_k127_5662631_3	386456.JQKN01000002_gene2525	2.55e-27	120.0	COG1669@1|root,arCOG01206@2157|Archaea,2Y02Z@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM DNA polymerase, beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
DPH1_k127_5662631_1	13035.Dacsa_0098	2.232e-28	118.0	COG2361@1|root,COG2361@2|Bacteria,1G9J5@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
DPH1_k127_5662631_0	243164.DET1501	1.309e-32	131.0	COG0716@1|root,COG0716@2|Bacteria,2GAZ4@200795|Chloroflexi,34DME@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5676700_0	673860.AciM339_1497	0.0	1123.0	COG1933@1|root,arCOG04447@2157|Archaea,2XU5S@28890|Euryarchaeota,3F2HV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Intein_splicing,LAGLIDADG_3,PolC_DP2
DPH1_k127_5676700_3	1156919.QWC_09581	2.842e-06	59.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,3T3SQ@506|Alcaligenaceae	28216|Betaproteobacteria	GM	NAD dependent epimerase dehydratase family protein	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
DPH1_k127_5676700_1	529709.PYCH_16880	6.819e-133	448.0	COG1297@1|root,arCOG04807@2157|Archaea,2XVCD@28890|Euryarchaeota,243GY@183968|Thermococci	183968|Thermococci	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DPH1_k127_5676700_2	903814.ELI_1761	3.045e-11	69.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,25X6B@186806|Eubacteriaceae	186801|Clostridia	S	NOG20192 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
DPH1_k127_5680218_3	1197130.BAFM01000005_gene1173	4.818e-13	70.0	COG1370@1|root,arCOG00991@2157|Archaea,2XYFT@28890|Euryarchaeota,23W9Y@183963|Halobacteria	183963|Halobacteria	O	COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit	-	-	-	ko:K07398	-	-	-	-	ko00000	-	-	-	PUA,TGT_C2
DPH1_k127_5680218_2	926569.ANT_01120	8.661e-20	105.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_5680218_0	1123288.SOV_3c05790	5.374e-73	254.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_5680218_1	1197130.BAFM01000005_gene1173	1.515e-25	109.0	COG1370@1|root,arCOG00991@2157|Archaea,2XYFT@28890|Euryarchaeota,23W9Y@183963|Halobacteria	183963|Halobacteria	O	COG1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit	-	-	-	ko:K07398	-	-	-	-	ko00000	-	-	-	PUA,TGT_C2
DPH1_k127_569412_0	717606.PaecuDRAFT_2033	2.742e-65	246.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_569412_1	189425.PGRAT_26160	1.497e-12	76.0	COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Flg_new,SLH,fn3
DPH1_k127_569572_0	66269.NL54_14970	3.133e-15	90.0	COG2911@1|root,COG2911@2|Bacteria,1P8N9@1224|Proteobacteria,1T1IH@1236|Gammaproteobacteria,3VXVZ@53335|Pantoea	1236|Gammaproteobacteria	M	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3
DPH1_k127_569572_1	90371.CY43_22240	1.511e-13	86.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,3ZJZS@590|Salmonella	1236|Gammaproteobacteria	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,VCBS
DPH1_k127_569572_2	1307761.L21SP2_3111	3e-09	71.0	COG3210@1|root,COG3210@2|Bacteria,2JBDG@203691|Spirochaetes	203691|Spirochaetes	U	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
DPH1_k127_5744923_0	273116.14325439	1.025e-96	331.0	COG1960@1|root,arCOG04310@2157|Archaea,2XXBZ@28890|Euryarchaeota,2426V@183967|Thermoplasmata	183967|Thermoplasmata	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_5744923_2	1121396.KB893071_gene1266	1.413e-15	87.0	COG1146@1|root,COG1146@2|Bacteria,1N25W@1224|Proteobacteria,42UPT@68525|delta/epsilon subdivisions,2WQT1@28221|Deltaproteobacteria,2MKHB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
DPH1_k127_5744923_1	523850.TON_0584	1.072e-72	252.0	COG0674@1|root,arCOG01607@2157|Archaea,2Y7K5@28890|Euryarchaeota,2439W@183968|Thermococci	183968|Thermococci	C	ferredoxin oxidoreductase, subunit alpha	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DPH1_k127_5764022_2	1449063.JMLS01000030_gene469	6.961e-07	62.0	2DBQW@1|root,2ZAH4@2|Bacteria,1UYN3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_5764022_3	857293.CAAU_2425	1.475e-05	58.0	COG1387@1|root,COG1409@1|root,COG5263@1|root,COG1387@2|Bacteria,COG1409@2|Bacteria,COG5263@2|Bacteria,1VUGT@1239|Firmicutes,25F7D@186801|Clostridia,36UY8@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,DUF3604
DPH1_k127_5764022_0	593117.TGAM_0168	5.305e-45	171.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,243RS@183968|Thermococci	183968|Thermococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DPH1_k127_5764022_1	5061.CADANGAP00007804	2.034e-12	72.0	COG3642@1|root,KOG3087@2759|Eukaryota,38E5H@33154|Opisthokonta,3NVEV@4751|Fungi,3QMMM@4890|Ascomycota,20AHT@147545|Eurotiomycetes,3S3ED@5042|Eurotiales	4751|Fungi	T	Component of the EKC KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Bud32 has ATPase activity in the context of the EKC KEOPS complex and likely plays a supporting role to the catalytic subunit kae1. The EKC KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators (By similarity)	BUD32	GO:0000003,GO:0000166,GO:0000278,GO:0000281,GO:0000282,GO:0000408,GO:0000722,GO:0000723,GO:0000910,GO:0002949,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006312,GO:0006355,GO:0006357,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007163,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009653,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019954,GO:0022402,GO:0030010,GO:0030154,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032200,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043934,GO:0043936,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051276,GO:0051301,GO:0060249,GO:0060255,GO:0061640,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902680,GO:1903047,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	APH,Kdo,Pkinase
DPH1_k127_5803648_2	246197.MXAN_3564	0.000149	53.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36,Peptidase_M6
DPH1_k127_5803648_1	765420.OSCT_0887	3.546e-50	206.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
DPH1_k127_5803648_0	439481.Aboo_1545	1.801e-57	209.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota,3F328@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_5887768_5	1440774.Y900_002195	0.0009201	45.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria,23APC@1762|Mycobacteriaceae	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
DPH1_k127_5887768_0	1054217.TALC_01492	3.434e-110	367.0	COG0309@1|root,arCOG00636@2157|Archaea,2XTAH@28890|Euryarchaeota,241W7@183967|Thermoplasmata	183967|Thermoplasmata	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DPH1_k127_5887768_1	1382306.JNIM01000001_gene194	4.985e-103	348.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi	200795|Chloroflexi	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
DPH1_k127_5887768_4	647113.Metok_1476	4.96e-17	87.0	COG0375@1|root,arCOG04426@2157|Archaea,2XY46@28890|Euryarchaeota,23QZX@183939|Methanococci	183939|Methanococci	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
DPH1_k127_5887768_3	1054217.TALC_01355	1.058e-18	92.0	COG0298@1|root,arCOG04427@2157|Archaea,2Y0AJ@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
DPH1_k127_5887768_2	1236689.MMALV_04840	1.312e-68	246.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota,3F2IG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TIGRFAM NiFe hydrogenase maturation protein HypF	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
DPH1_k127_5892881_5	765910.MARPU_10900	1.088e-12	72.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria,1WY53@135613|Chromatiales	135613|Chromatiales	P	Belongs to the DsrF TusC family	dsrF	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
DPH1_k127_5892881_3	187272.Mlg_1655	6.708e-15	79.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1WY2D@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein TusD DsrE	dsrE	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
DPH1_k127_5892881_1	419665.Maeo_0966	9.187e-35	138.0	COG2210@1|root,arCOG02064@2157|Archaea,2XT1G@28890|Euryarchaeota	28890|Euryarchaeota	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
DPH1_k127_5892881_2	1121101.HMPREF1532_03733	4.998e-31	143.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
DPH1_k127_5892881_4	344747.PM8797T_02424	4.568e-13	84.0	COG1404@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG4932@1|root,COG5276@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.4,3.4.21.62,3.4.24.40	ko:K01179,ko:K01342,ko:K01406,ko:K07004,ko:K12287,ko:K14194,ko:K15125,ko:K20276	ko00500,ko01100,ko01503,ko02024,ko05133,ko05150,map00500,map01100,map01503,map02024,map05133,map05150	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko02044,ko03110	-	GH5,GH9	-	Calx-beta,Exo_endo_phos,HemolysinCabind,VCBS
DPH1_k127_5892881_0	1054217.TALC_01148	1.97e-39	153.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,241NZ@183967|Thermoplasmata	183967|Thermoplasmata	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
DPH1_k127_5925118_3	1440053.JOEI01000007_gene2532	3.175e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
DPH1_k127_5925118_1	439481.Aboo_0164	8.512e-67	237.0	COG1578@1|root,arCOG04410@2157|Archaea,2XWGU@28890|Euryarchaeota,3F2KN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
DPH1_k127_5925118_2	935948.KE386495_gene1762	1.379e-18	96.0	COG2119@1|root,COG2119@2|Bacteria,1UFX2@1239|Firmicutes,24DHF@186801|Clostridia,42GAG@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
DPH1_k127_5925118_0	1291050.JAGE01000001_gene1624	7.848e-90	298.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,3WI1K@541000|Ruminococcaceae	186801|Clostridia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
DPH1_k127_5971856_4	693661.Arcve_1632	4.015e-10	66.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
DPH1_k127_5971856_2	582515.KR51_00015040	6.956e-19	104.0	COG0457@1|root,COG0457@2|Bacteria,1G3E6@1117|Cyanobacteria	1117|Cyanobacteria	L	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
DPH1_k127_5971856_0	269797.Mbar_A0011	5.685e-114	417.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
DPH1_k127_5971856_3	744872.Spica_2769	3.252e-17	98.0	COG0457@1|root,COG0457@2|Bacteria,2J780@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
DPH1_k127_5971856_1	33898.JRHJ01000050_gene8112	4.822e-21	102.0	COG2153@1|root,COG2153@2|Bacteria,2IFAM@201174|Actinobacteria	201174|Actinobacteria	F	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
DPH1_k127_5971856_5	1112216.JH594425_gene1244	9.611e-08	66.0	COG2911@1|root,COG2931@1|root,COG2982@1|root,COG3637@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3637@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K0IP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,He_PIG,HemolysinCabind
DPH1_k127_597482_0	1379281.AVAG01000078_gene1562	2.021e-149	486.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2M8W7@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DPH1_k127_597482_1	529709.PYCH_09500	2.614e-81	284.0	COG0281@1|root,arCOG01331@2157|Archaea,2XTRZ@28890|Euryarchaeota,242SQ@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
DPH1_k127_5992150_0	673860.AciM339_0266	5.112e-88	301.0	COG1235@1|root,arCOG00499@2157|Archaea,2XT48@28890|Euryarchaeota,3F2JB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DPH1_k127_5992150_2	644966.Tmar_1747	2.367e-45	185.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia	1239|Firmicutes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DPH1_k127_5992150_1	589924.Ferp_0942	1.039e-46	182.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota,245SC@183980|Archaeoglobi	183980|Archaeoglobi	C	4Fe-4S dicluster domain	-	-	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17
DPH1_k127_6019617_8	888064.HMPREF9088_1142	1.664e-12	72.0	COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,4B0MV@81852|Enterococcaceae	91061|Bacilli	S	Flotillin	floL	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
DPH1_k127_6019617_7	1125863.JAFN01000001_gene1784	1.076e-34	138.0	COG1150@1|root,COG1150@2|Bacteria,1NFJN@1224|Proteobacteria,43B2A@68525|delta/epsilon subdivisions,2X6GB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17
DPH1_k127_6019617_3	765912.Thimo_0248	3.686e-86	294.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,1SBBX@1236|Gammaproteobacteria,1X060@135613|Chromatiales	135613|Chromatiales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DPH1_k127_6019617_0	443143.GM18_3239	2.102e-231	735.0	COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,FlpD,Pyr_redox_2
DPH1_k127_6019617_5	429009.Adeg_2015	1.586e-56	201.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
DPH1_k127_6019617_4	1125863.JAFN01000001_gene1776	2.981e-63	230.0	COG1150@1|root,COG1150@2|Bacteria,1R1YD@1224|Proteobacteria,43DCI@68525|delta/epsilon subdivisions,2X8II@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6019617_2	760568.Desku_1500	1.643e-88	299.0	COG1152@1|root,COG1152@2|Bacteria,1UKJG@1239|Firmicutes,25FYP@186801|Clostridia,26446@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_10,Fer4_9
DPH1_k127_6019617_1	760568.Desku_1499	1.768e-222	701.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,264B9@186807|Peptococcaceae	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
DPH1_k127_6019617_6	429009.Adeg_0342	1.819e-55	205.0	COG1148@1|root,COG1148@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,42FPJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	FlpD,Pyr_redox_2
DPH1_k127_611300_1	330214.NIDE3695	0.0001273	45.0	COG5033@1|root,COG5033@2|Bacteria	2|Bacteria	K	chromatin organization	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,YEATS
DPH1_k127_611300_0	243164.DET0811	2.88e-73	258.0	COG1233@1|root,COG1233@2|Bacteria,2G5ZA@200795|Chloroflexi,34D93@301297|Dehalococcoidia	301297|Dehalococcoidia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DPH1_k127_6129774_0	290318.Cvib_0321	4.309e-05	55.0	COG1629@1|root,COG4771@2|Bacteria,1FDET@1090|Chlorobi	1090|Chlorobi	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DPH1_k127_6152843_0	1379698.RBG1_1C00001G0047	8.374e-121	396.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
DPH1_k127_6152843_2	1236689.MMALV_13670	2.764e-47	178.0	COG2048@1|root,arCOG00964@2157|Archaea,2XZ7E@28890|Euryarchaeota,3F2WA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
DPH1_k127_6152843_1	224719.Abm4_1308	6.424e-102	338.0	COG2048@1|root,arCOG00338@2157|Archaea,2XTWJ@28890|Euryarchaeota,23NJW@183925|Methanobacteria	183925|Methanobacteria	C	reductase, subunit	hdrB1	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DPH1_k127_6152843_3	572477.Alvin_0806	3.674e-13	77.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,1SIG2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Hydrogenase maturation protease	vhtD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
DPH1_k127_6152843_4	572477.Alvin_0806	0.0003244	48.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,1SIG2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Hydrogenase maturation protease	vhtD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
DPH1_k127_6152968_3	1216932.CM240_2715	2.748e-05	51.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,36K5Z@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DPH1_k127_6152968_1	652103.Rpdx1_0901	7.724e-41	156.0	COG0662@1|root,COG0662@2|Bacteria,1NG5P@1224|Proteobacteria,2UMGS@28211|Alphaproteobacteria,3K68C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DPH1_k127_6152968_0	880073.Calab_1228	3.139e-60	215.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
DPH1_k127_6152968_2	1247726.MIM_c23970	1.435e-05	52.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VR8Y@28216|Betaproteobacteria,3T3IJ@506|Alcaligenaceae	28216|Betaproteobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DPH1_k127_6183654_12	1226322.HMPREF1545_01985	2.94e-06	52.0	COG0110@1|root,COG0110@2|Bacteria,1V8CV@1239|Firmicutes,25KVH@186801|Clostridia,2N8KK@216572|Oscillospiraceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DPH1_k127_6183654_8	398512.JQKC01000002_gene1894	1.025e-19	91.0	COG0381@1|root,COG0381@2|Bacteria,1TQKQ@1239|Firmicutes,24A0H@186801|Clostridia,3WIAQ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing	neuC	-	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DPH1_k127_6183654_4	547559.Nmag_0149	6.448e-76	265.0	COG0381@1|root,arCOG01392@2157|Archaea,2XW1D@28890|Euryarchaeota,23ZM3@183963|Halobacteria	183963|Halobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2
DPH1_k127_6183654_5	717606.PaecuDRAFT_2136	8.473e-33	147.0	COG1520@1|root,COG3210@1|root,COG4412@1|root,COG5276@1|root,COG5492@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG4412@2|Bacteria,COG5276@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
DPH1_k127_6183654_6	383372.Rcas_0459	4.746e-23	116.0	COG1216@1|root,COG1216@2|Bacteria,2G6TR@200795|Chloroflexi,3769F@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
DPH1_k127_6183654_0	593750.Metfor_1238	9.328e-284	895.0	COG2217@1|root,arCOG02763@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DPH1_k127_6183654_11	673860.AciM339_1041	1.455e-06	56.0	arCOG03672@1|root,arCOG08126@1|root,arCOG03672@2157|Archaea,arCOG08126@2157|Archaea,2Y73H@28890|Euryarchaeota,3F3BZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
DPH1_k127_6183654_3	251221.35214774	3.944e-111	405.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
DPH1_k127_6183654_10	1219076.N646_4601	1.026e-06	63.0	COG2911@1|root,COG2931@1|root,COG3209@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0044877,GO:0051704,GO:0070051,GO:0098630,GO:0098743	-	ko:K14192,ko:K14194,ko:K14201	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	Gram_pos_anchor
DPH1_k127_6183654_2	945713.IALB_2155	2.095e-138	455.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iPC815.YPO3230,iSBO_1134.SBO_0243	M20_dimer,Peptidase_M20
DPH1_k127_6183654_1	880073.Calab_1015	8.273e-164	541.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	PD40,Peptidase_S9
DPH1_k127_6183654_7	386456.JQKN01000009_gene1129	5.359e-21	109.0	COG3291@1|root,arCOG02555@1|root,arCOG07611@1|root,arCOG02546@2157|Archaea,arCOG02555@2157|Archaea,arCOG07611@2157|Archaea	2157|Archaea	E	Conserved repeat domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_5,CARDB,CHB_HEX_C_1,CarboxypepD_reg,Cellulase,DUF11,PKD,PQQ_3,SBBP,VWA
DPH1_k127_6207276_0	264732.Moth_0808	2.717e-31	138.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,24BZ3@186801|Clostridia,42GGS@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DPH1_k127_6207276_1	880073.Calab_2183	3.344e-14	87.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Calx-beta,DUF5122,Haemagg_act,HemolysinCabind,PPC,VCBS
DPH1_k127_6209983_0	641526.ADIWIN_4066	1.029e-13	85.0	COG2706@1|root,COG2706@2|Bacteria,4NN57@976|Bacteroidetes,1I1TD@117743|Flavobacteriia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_6209983_1	756883.Halar_3273	4.57e-07	61.0	COG3398@1|root,arCOG02611@2157|Archaea	2157|Archaea	K	protein conserved in archaea	gntR	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	HTH_24,HTH_5,MarR_2,V4R
DPH1_k127_6220757_3	751944.HALDL1_08460	1.066e-15	90.0	COG0577@1|root,arCOG02312@2157|Archaea,2XUEE@28890|Euryarchaeota,23T52@183963|Halobacteria	183963|Halobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_6220757_4	457412.RSAG_03346	2.005e-12	80.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3WHUM@541000|Ruminococcaceae	186801|Clostridia	V	MacB-like periplasmic core domain	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_6220757_0	273068.TTE0257	7.543e-69	242.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,42FTY@68295|Thermoanaerobacterales	186801|Clostridia	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_6220757_1	1042877.GQS_03500	3.602e-39	156.0	COG0561@1|root,arCOG01213@2157|Archaea,2XX94@28890|Euryarchaeota,242JB@183968|Thermococci	183968|Thermococci	G	Catalyzes the dephosphorylation of 2-phosphoglycolate	-	-	3.1.3.18	ko:K22223	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
DPH1_k127_6220757_2	273075.Ta0724	5.414e-38	148.0	COG1373@1|root,arCOG03167@2157|Archaea	2157|Archaea	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DPH1_k127_6223943_4	439481.Aboo_1487	3.559e-07	55.0	COG3390@1|root,arCOG02258@2157|Archaea,2Y7QP@28890|Euryarchaeota,3F2PB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	protein conserved in archaea	-	-	-	ko:K09746	-	-	-	-	ko00000	-	-	-	-
DPH1_k127_6223943_1	521011.Mpal_1231	3.241e-41	160.0	COG4978@1|root,arCOG03200@2157|Archaea,2XYDM@28890|Euryarchaeota,2NBJ9@224756|Methanomicrobia	224756|Methanomicrobia	K	transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
DPH1_k127_6223943_2	679926.Mpet_1614	2.309e-28	120.0	arCOG03571@1|root,arCOG03571@2157|Archaea,2Y1I5@28890|Euryarchaeota,2NB7Q@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
DPH1_k127_6223943_0	387631.Asulf_00513	1.897e-41	156.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,2469B@183980|Archaeoglobi	183980|Archaeoglobi	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DPH1_k127_6223943_3	439235.Dalk_3455	1.405e-18	93.0	COG0655@1|root,COG0655@2|Bacteria,1NANP@1224|Proteobacteria,42Q16@68525|delta/epsilon subdivisions,2WIJ7@28221|Deltaproteobacteria,2MIC1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,LMWPc
DPH1_k127_6225811_2	479434.Sthe_1775	1.69e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_6225811_1	479434.Sthe_1776	5.086e-99	358.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
DPH1_k127_6225811_3	368407.Memar_1073	7.458e-50	188.0	arCOG02449@1|root,arCOG02449@2157|Archaea,2XZ1K@28890|Euryarchaeota,2NAXS@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
DPH1_k127_6225811_0	562970.Btus_0928	5.943e-252	788.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,2782U@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
DPH1_k127_6225811_4	1448860.BBJO01000014_gene1427	2.497e-31	131.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XVHG@28890|Euryarchaeota,23SZN@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	HTH_10
DPH1_k127_6225811_5	1033743.CAES01000085_gene2958	3.157e-18	98.0	COG1404@1|root,COG2730@1|root,COG1404@2|Bacteria,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	celA7	-	3.2.1.4,3.2.1.78	ko:K01179,ko:K01218	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH26,GH5,GH9	-	CBM_3,CBM_35,F5_F8_type_C,Glyco_hydro_26,Glyco_hydro_44,Peptidase_S8,SLH,fn3
DPH1_k127_6305855_3	1455608.JDTH01000002_gene1656	5.881e-46	176.0	COG0500@1|root,arCOG04989@2157|Archaea,2XWEU@28890|Euryarchaeota,23V0C@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DPH1_k127_6305855_5	673860.AciM339_0947	4.295e-39	159.0	COG1041@1|root,arCOG00047@2157|Archaea,2XTD6@28890|Euryarchaeota,3F2QX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Pfam:Methyltransf_26	trmG10	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
DPH1_k127_6305855_2	439481.Aboo_0831	4.933e-49	198.0	COG0543@1|root,arCOG02199@2157|Archaea,2XSY9@28890|Euryarchaeota,3F2KR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DPH1_k127_6305855_1	186497.PF1539	2.589e-81	280.0	COG0167@1|root,arCOG00603@2157|Archaea,2XTMB@28890|Euryarchaeota,2430R@183968|Thermococci	183968|Thermococci	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DPH1_k127_6305855_4	351160.RCIX1084	2.799e-44	184.0	COG0840@1|root,arCOG02348@1|root,arCOG02320@2157|Archaea,arCOG02348@2157|Archaea	2157|Archaea	T	PAS domain	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
DPH1_k127_6305855_0	673860.AciM339_0595	1.446e-96	328.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTI9@28890|Euryarchaeota,3F2JJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Belongs to the peptidase M24B family	pepQ1	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
DPH1_k127_6305855_6	877455.Metbo_0292	1.773e-30	128.0	COG0720@1|root,arCOG02172@2157|Archaea,2XXFY@28890|Euryarchaeota,23PMK@183925|Methanobacteria	183925|Methanobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DPH1_k127_6348323_0	179408.Osc7112_5813	2.38e-79	299.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
DPH1_k127_6348323_1	215803.DB30_1737	1.248e-34	155.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1QABW@1224|Proteobacteria,43DZH@68525|delta/epsilon subdivisions,2WZ9U@28221|Deltaproteobacteria,2Z1NM@29|Myxococcales	28221|Deltaproteobacteria	O	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6348323_2	1174528.JH992898_gene984	0.0005541	54.0	COG2319@1|root,COG2319@2|Bacteria,1G2F6@1117|Cyanobacteria,1JH3N@1189|Stigonemataceae	1117|Cyanobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,WD40
DPH1_k127_6376207_3	644966.Tmar_0853	2.275e-93	318.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WCFH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DPH1_k127_6376207_2	266117.Rxyl_1330	1.403e-100	344.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CPB3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DPH1_k127_6376207_5	439481.Aboo_0797	5.226e-27	117.0	COG1599@1|root,arCOG01510@2157|Archaea,2Y72Y@28890|Euryarchaeota,3F3AT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
DPH1_k127_6376207_4	398767.Glov_1752	2.597e-45	172.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2WMR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
DPH1_k127_6376207_0	697303.Thewi_0932	7.656e-129	428.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,42FDT@68295|Thermoanaerobacterales	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DPH1_k127_6376207_7	1121396.KB893070_gene1332	1.028e-22	108.0	COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42P2D@68525|delta/epsilon subdivisions,2WKSQ@28221|Deltaproteobacteria,2MJF4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DPH1_k127_6376207_1	593750.Metfor_2721	6.748e-116	391.0	COG0798@1|root,arCOG02190@2157|Archaea,2XTQC@28890|Euryarchaeota,2N935@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
DPH1_k127_6376207_10	1165841.SULAR_02313	2.086e-07	63.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2YP7U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
DPH1_k127_6376207_6	368407.Memar_0018	7.279e-25	106.0	COG0526@1|root,arCOG02713@2157|Archaea,2Y18H@28890|Euryarchaeota,2NA1S@224756|Methanomicrobia	224756|Methanomicrobia	O	Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
DPH1_k127_6376207_8	593750.Metfor_2728	1.412e-13	73.0	arCOG03645@1|root,arCOG03645@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6376207_9	760568.Desku_0294	6.435e-11	64.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,260D6@186807|Peptococcaceae	186801|Clostridia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
DPH1_k127_6431892_8	362976.HQ_3250A	0.0001412	49.0	COG2811@1|root,arCOG03363@2157|Archaea,2XXSF@28890|Euryarchaeota,23W9I@183963|Halobacteria	183963|Halobacteria	C	TIGRFAM ATP synthase	atpH	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_B,V-ATPase_G_2
DPH1_k127_6431892_2	304371.MCP_0344	8.31e-87	312.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2N9EB@224756|Methanomicrobia	224756|Methanomicrobia	C	Belongs to the V-ATPase 116 kDa subunit family	atpI-1	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
DPH1_k127_6431892_7	523841.HFX_0298	6.479e-10	63.0	COG0636@1|root,arCOG02455@2157|Archaea,2XZRP@28890|Euryarchaeota,23XH5@183963|Halobacteria	183963|Halobacteria	C	F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K	atpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
DPH1_k127_6431892_5	1094980.Mpsy_2503	3.905e-23	106.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,2N9TB@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
DPH1_k127_6431892_4	351160.RCIX2028	5.59e-60	221.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,2N9HH@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0388	vATP-synt_AC39
DPH1_k127_6431892_6	351160.RCIX2029	5.291e-17	85.0	COG1436@1|root,arCOG04102@2157|Archaea,2XXYI@28890|Euryarchaeota,2N9YY@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
DPH1_k127_6431892_0	565033.GACE_1731	6.132e-259	809.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,246Y7@183980|Archaeoglobi	183980|Archaeoglobi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
DPH1_k127_6431892_1	1041930.Mtc_1395	1.426e-241	758.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2N97D@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
DPH1_k127_6431892_3	1094980.Mpsy_2508	4.911e-64	244.0	COG1394@1|root,arCOG04101@2157|Archaea,2XTQ5@28890|Euryarchaeota,2N9IG@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0384	ATP-synt_D
DPH1_k127_6478992_0	349520.PPE_04510	4.55e-102	351.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBVK@91061|Bacilli,26QF5@186822|Paenibacillaceae	91061|Bacilli	L	helicase	deaD3	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
DPH1_k127_6478992_1	46234.ANA_C13379	1.402e-07	65.0	COG1572@1|root,COG4932@1|root,COG1572@2|Bacteria,COG4932@2|Bacteria,1G1E0@1117|Cyanobacteria,1HMS7@1161|Nostocales	1117|Cyanobacteria	M	Calpain-like thiol protease family.	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,PPC,Peptidase_C2
DPH1_k127_6478992_2	1348908.KI518590_gene2796	0.0005607	53.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8
DPH1_k127_6517627_3	673860.AciM339_0143	6.235e-05	51.0	COG2443@1|root,arCOG02204@2157|Archaea,2Y6IU@28890|Euryarchaeota,3F2UZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	TIGRFAM protein translocase SEC61 complex gamma subunit	-	-	-	ko:K07342	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.7,3.A.5.8,3.A.5.9	-	-	-
DPH1_k127_6517627_0	673860.AciM339_0142	9.354e-143	462.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F32D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DPH1_k127_6517627_1	673860.AciM339_0142	2.859e-132	436.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F32D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DPH1_k127_6517627_2	673860.AciM339_0010	3.906e-12	81.0	COG1361@1|root,arCOG01917@1|root,arCOG05791@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG04400@2157|Archaea,arCOG05791@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
DPH1_k127_6545991_0	237368.SCABRO_03564	2.065e-15	91.0	COG3291@1|root,COG3291@2|Bacteria,2J1GZ@203682|Planctomycetes	203682|Planctomycetes	U	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_6545991_2	394503.Ccel_1097	0.0008415	53.0	COG1657@1|root,COG3055@1|root,COG3469@1|root,COG4257@1|root,COG1657@2|Bacteria,COG3055@2|Bacteria,COG3469@2|Bacteria,COG4257@2|Bacteria,1V2M9@1239|Firmicutes,24BYK@186801|Clostridia,36J6S@31979|Clostridiaceae	186801|Clostridia	GIV	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Prenyltrans
DPH1_k127_6583792_0	1227497.C491_05201	9.945e-87	308.0	COG1574@1|root,arCOG00691@2157|Archaea,2XUUZ@28890|Euryarchaeota,23SFX@183963|Halobacteria	183963|Halobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DPH1_k127_6583792_1	426355.Mrad2831_4421	7.24e-24	117.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,1JU5H@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
DPH1_k127_6586327_1	572479.Hprae_0073	2.365e-92	338.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WBDU@53433|Halanaerobiales	186801|Clostridia	E	threonine ammonia-lyase, biosynthetic, long form	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
DPH1_k127_6586327_0	1047013.AQSP01000140_gene2450	5.3e-127	418.0	COG0065@1|root,COG0065@2|Bacteria,2NNYT@2323|unclassified Bacteria	2|Bacteria	E	Aconitase family (aconitate hydratase)	hacA	-	4.2.1.114,4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01705,ko:K16792	ko00290,ko00300,ko00660,ko00680,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00680,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535,M00608	R03444,R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R09720,R10170,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DPH1_k127_6586327_2	867903.ThesuDRAFT_01082	6.287e-52	188.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WD25@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
DPH1_k127_6645554_2	1157638.KB892179_gene2270	0.0002896	45.0	COG1131@1|root,COG1131@2|Bacteria,2GNQJ@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_6645554_0	1386089.N865_05350	6.477e-55	219.0	COG4733@1|root,COG4733@2|Bacteria,2I7XV@201174|Actinobacteria,4FK2V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DPH1_k127_6645554_1	251221.35214774	2.322e-20	107.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
DPH1_k127_6648447_0	797303.Natpe_3933	7.11e-35	146.0	COG0438@1|root,arCOG01411@2157|Archaea,2Y8BS@28890|Euryarchaeota,2418K@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_6648447_2	760568.Desku_2432	4.618e-06	59.0	2B79F@1|root,320C5@2|Bacteria,1UV9B@1239|Firmicutes,25I7N@186801|Clostridia,266CF@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6648447_1	7739.XP_002600439.1	1.52e-06	61.0	29BDQ@1|root,2RIGR@2759|Eukaryota,39XEG@33154|Opisthokonta,3BY63@33208|Metazoa,3DE57@33213|Bilateria	33208|Metazoa	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF642
DPH1_k127_6682074_1	673860.AciM339_0730	6.62e-32	134.0	COG4934@1|root,arCOG05978@1|root,arCOG03669@2157|Archaea,arCOG05978@2157|Archaea,2Y7X2@28890|Euryarchaeota,3F38G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ,fn3
DPH1_k127_6682074_0	717606.PaecuDRAFT_2033	1.775e-74	284.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_6682074_2	673860.AciM339_0730	9.007e-29	136.0	COG4934@1|root,arCOG05978@1|root,arCOG03669@2157|Archaea,arCOG05978@2157|Archaea,2Y7X2@28890|Euryarchaeota,3F38G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ,fn3
DPH1_k127_6682074_3	1122222.AXWR01000037_gene279	3.894e-09	71.0	COG2372@1|root,COG4733@1|root,COG2372@2|Bacteria,COG4733@2|Bacteria,1WN17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DPH1_k127_6682527_1	1144275.COCOR_02134	3.755e-10	69.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,PKD
DPH1_k127_6682527_0	589924.Ferp_0234	1.956e-66	250.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
DPH1_k127_6693883_2	880072.Desac_0254	1.234e-19	91.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,NHL,Thioredoxin_8
DPH1_k127_6693883_0	1408422.JHYF01000018_gene1745	5.537e-110	368.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia,36E7U@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DPH1_k127_6693883_1	269799.Gmet_2510	9.766e-34	141.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,43T7Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DPH1_k127_6751711_0	572546.Arcpr_0668	9.831e-141	462.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,245RD@183980|Archaeoglobi	183980|Archaeoglobi	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DPH1_k127_6751711_3	457415.HMPREF1006_01186	6.719e-06	57.0	2ENZG@1|root,33GKC@2|Bacteria,3TBSZ@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6751711_1	112098.XP_008617539.1	1.84e-11	77.0	COG5599@1|root,KOG0613@1|root,KOG0613@2759|Eukaryota,KOG4228@2759|Eukaryota	2759|Eukaryota	T	protein tyrosine phosphatase activity	USH2A	-	-	ko:K17341,ko:K19636	-	-	-	-	ko00000,ko03036	-	-	-	Calx-beta,I-set,Ig_3,LRR_8,Laminin_EGF,Laminin_G_2,Laminin_G_3,Laminin_N,TRP,fn3,ig
DPH1_k127_6751711_2	1408433.JHXV01000041_gene3590	9.375e-07	62.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DPH1_k127_6777163_2	666510.ASAC_1278	9.924e-56	201.0	COG1838@1|root,arCOG04406@2157|Archaea,2XQ9V@28889|Crenarchaeota	28889|Crenarchaeota	C	Fe-S type, tartrate fumarate subfamily, beta	-	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
DPH1_k127_6777163_0	304371.MCP_0509	2.781e-90	319.0	COG1951@1|root,arCOG04407@2157|Archaea,2XUQI@28890|Euryarchaeota,2N9FT@224756|Methanomicrobia	224756|Methanomicrobia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
DPH1_k127_6777163_4	456442.Mboo_1722	2.281e-17	93.0	COG1836@1|root,arCOG02245@2157|Archaea,2XTBR@28890|Euryarchaeota,2N936@224756|Methanomicrobia	224756|Methanomicrobia	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
DPH1_k127_6777163_3	326427.Cagg_1210	1.046e-23	115.0	COG0382@1|root,COG0382@2|Bacteria,2GAH1@200795|Chloroflexi,3763F@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM bacteriochlorophyll chlorophyll synthetase	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_6777163_1	1236689.MMALV_01510	7.09e-65	239.0	COG1100@1|root,arCOG01225@2157|Archaea,2XWN4@28890|Euryarchaeota,3F2J6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
DPH1_k127_6784077_1	1265505.ATUG01000001_gene3591	4.226e-48	195.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MIBB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9,FlpD
DPH1_k127_6784077_2	1210908.HSB1_10950	4.289e-24	119.0	COG1290@1|root,arCOG04594@2157|Archaea,2XUW1@28890|Euryarchaeota,23S8Q@183963|Halobacteria	183963|Halobacteria	C	COG1290 Cytochrome b subunit of the bc complex	petD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
DPH1_k127_6784077_0	1132509.C447_07278	2.386e-82	296.0	COG1290@1|root,arCOG01721@2157|Archaea,2XUQH@28890|Euryarchaeota,23TXF@183963|Halobacteria	183963|Halobacteria	C	COG1290 Cytochrome b subunit of the bc complex	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
DPH1_k127_6806107_2	1231391.AMZF01000043_gene831	9.429e-07	53.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,3T4AX@506|Alcaligenaceae	28216|Betaproteobacteria	L	Uracil-DNA glycosylase	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DPH1_k127_6806107_1	439481.Aboo_0215	1.114e-11	70.0	COG1719@1|root,arCOG01688@2157|Archaea	2157|Archaea	K	PFAM 4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	DUF2507,V4R
DPH1_k127_6806107_0	673860.AciM339_0604	1.198e-40	161.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4UK@28890|Euryarchaeota,3F2ZZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	GvpD gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_6806107_3	523841.HFX_0561	4.131e-05	49.0	COG3609@1|root,arCOG01009@2157|Archaea,2XZTH@28890|Euryarchaeota,23XHR@183963|Halobacteria	183963|Halobacteria	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
DPH1_k127_6839288_1	342949.PNA2_1011	1.511e-06	60.0	arCOG01314@1|root,arCOG01314@2157|Archaea,2XVNC@28890|Euryarchaeota,243S2@183968|Thermococci	183968|Thermococci	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
DPH1_k127_6839288_0	935845.JADQ01000033_gene2150	6.978e-13	83.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,26QNY@186822|Paenibacillaceae	91061|Bacilli	O	CarboxypepD_reg-like domain	bprF	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
DPH1_k127_684569_0	404589.Anae109_1425	1.881e-41	168.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2Z144@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_684569_1	535289.Dtpsy_1808	9.819e-07	52.0	COG0697@1|root,COG0697@2|Bacteria,1N3FA@1224|Proteobacteria,2VHAD@28216|Betaproteobacteria,4ABD4@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Drug metabolite transporter	cnrT	-	-	-	-	-	-	-	-	-	-	-	EamA
DPH1_k127_6850343_5	266117.Rxyl_3161	0.0004185	44.0	COG0457@1|root,COG0457@2|Bacteria	266117.Rxyl_3161|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_6850343_2	1128421.JAGA01000003_gene2766	1.041e-60	241.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
DPH1_k127_6850343_3	1128421.JAGA01000003_gene2766	2.351e-45	189.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
DPH1_k127_6850343_1	1379698.RBG1_1C00001G1092	9.21e-68	262.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
DPH1_k127_6850343_0	555079.Toce_1201	4.902e-174	554.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DPH1_k127_6850343_4	478741.JAFS01000001_gene1052	1.811e-07	53.0	COG2379@1|root,COG2379@2|Bacteria	2|Bacteria	G	hydroxypyruvate reductase	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
DPH1_k127_6887692_0	1094980.Mpsy_1982	2.699e-80	300.0	arCOG02487@1|root,arCOG02487@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
DPH1_k127_6891662_3	439481.Aboo_0002	7.162e-35	147.0	COG0681@1|root,arCOG01739@2157|Archaea,2Y6XH@28890|Euryarchaeota,3F2QN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
DPH1_k127_6891662_0	439481.Aboo_0001	9.071e-139	454.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,3F2IJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in regulation of DNA replication	cdc6	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA,AAA_16,AAA_22,Cdc6_C
DPH1_k127_6891662_1	1343739.PAP_04290	2.025e-64	245.0	COG2262@1|root,arCOG00353@2157|Archaea,2XT2W@28890|Euryarchaeota,2431W@183968|Thermococci	183968|Thermococci	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DPH1_k127_6891662_2	765910.MARPU_08855	1.144e-58	211.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HhH-GPD	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
DPH1_k127_6891662_4	1094980.Mpsy_2612	1.723e-34	141.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_6891662_5	593750.Metfor_0996	1.176e-20	94.0	COG1243@1|root,arCOG01361@2157|Archaea,2XT9Z@28890|Euryarchaeota,2N9D5@224756|Methanomicrobia	224756|Methanomicrobia	K	TIGRFAM histone acetyltransferase, ELP3 family	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
DPH1_k127_6915525_0	1001530.BACE01000026_gene1351	3.52e-23	117.0	COG1075@1|root,COG2304@1|root,COG5183@1|root,COG1075@2|Bacteria,COG2304@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,1XVD5@135623|Vibrionales	135623|Vibrionales	A	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,TSP_3
DPH1_k127_6915525_1	357809.Cphy_3771	7.37e-05	55.0	COG1198@1|root,COG4260@1|root,COG1198@2|Bacteria,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,21Z80@1506553|Lachnoclostridium	186801|Clostridia	L	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
DPH1_k127_6915525_2	1460634.JCM19037_2771	0.0001795	53.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M_N,CarboxypepD_reg
DPH1_k127_694986_6	90814.KL370892_gene2138	8.229e-07	62.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,1RS7G@1236|Gammaproteobacteria,46256@72273|Thiotrichales	72273|Thiotrichales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DPH1_k127_694986_4	383372.Rcas_3603	4.795e-26	123.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
DPH1_k127_694986_2	269797.Mbar_A1866	1.138e-67	241.0	COG1712@1|root,arCOG00254@2157|Archaea,2XUNA@28890|Euryarchaeota,2NBJI@224756|Methanomicrobia	224756|Methanomicrobia	F	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
DPH1_k127_694986_1	1343739.PAP_08635	1.4e-81	285.0	COG1313@1|root,arCOG00934@2157|Archaea,2XUM6@28890|Euryarchaeota,242QN@183968|Thermococci	183968|Thermococci	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DPH1_k127_694986_5	323259.Mhun_0933	1.001e-18	96.0	COG2426@1|root,arCOG01330@2157|Archaea,2Y4KG@28890|Euryarchaeota	28890|Euryarchaeota	S	Small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DPH1_k127_694986_0	523845.AQXV01000019_gene364	6.977e-265	840.0	COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,23QDK@183939|Methanococci	183939|Methanococci	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
DPH1_k127_694986_3	926554.KI912660_gene2372	2.766e-41	178.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
DPH1_k127_6966579_4	445972.ANACOL_04086	2.953e-11	72.0	COG1251@1|root,COG1251@2|Bacteria,1TQYX@1239|Firmicutes,24AD5@186801|Clostridia,3WHY7@541000|Ruminococcaceae	186801|Clostridia	C	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
DPH1_k127_6966579_3	192952.MM_2042	2.078e-18	96.0	COG3355@1|root,arCOG02242@2157|Archaea,2XX1H@28890|Euryarchaeota,2NB0S@224756|Methanomicrobia	224756|Methanomicrobia	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DPH1_k127_6966579_2	264732.Moth_0436	1.133e-20	95.0	COG0425@1|root,COG0425@2|Bacteria,1UF14@1239|Firmicutes,25K1R@186801|Clostridia,42IV0@68295|Thermoanaerobacterales	2|Bacteria	O	Sulfurtransferase TusA	yrkI	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	-	-	-	-	-	-	-	-	-	Rhodanese,TusA
DPH1_k127_6966579_5	1121015.N789_04830	0.000488	48.0	COG1765@1|root,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,1RMZV@1236|Gammaproteobacteria,1XBZ8@135614|Xanthomonadales	135614|Xanthomonadales	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DPH1_k127_6966579_0	269797.Mbar_A1077	1.374e-36	147.0	COG1237@1|root,arCOG00503@2157|Archaea,2XXGE@28890|Euryarchaeota,2N9XT@224756|Methanomicrobia	224756|Methanomicrobia	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
DPH1_k127_6966579_1	439481.Aboo_0741	2.492e-23	112.0	COG1672@1|root,COG3398@1|root,arCOG02611@2157|Archaea,arCOG03166@2157|Archaea	2157|Archaea	K	ATPase, AAA superfamily	deoR2	-	3.6.4.12,4.2.3.1,6.3.4.15	ko:K01733,ko:K02039,ko:K03436,ko:K03524,ko:K03655	ko00260,ko00750,ko00780,ko01100,ko01110,ko01120,ko01230,ko03440,map00260,map00750,map00780,map01100,map01110,map01120,map01230,map03440	M00018	R01074,R01466,R05086,R05145	RC00017,RC00043,RC00070,RC00096,RC00526,RC02896	ko00000,ko00001,ko00002,ko01000,ko03000,ko03400	-	-	-	BPL_C,BPL_LplA_LipB,DeoRC,HTH_11,HTH_24,HTH_DeoR,MarR_2,PhoU
DPH1_k127_6973833_0	374847.Kcr_0030	1.037e-67	246.0	COG1042@1|root,arCOG01340@2157|Archaea	2157|Archaea	C	Acyl-CoA synthetase (NDP forming)	acdA	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DPH1_k127_6973833_2	1104324.P186_1420	1.399e-31	141.0	COG1042@1|root,arCOG01338@2157|Archaea,2XQ9M@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM ATP-grasp domain	-	-	6.2.1.13	ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5
DPH1_k127_6973833_1	555088.DealDRAFT_2234	3.555e-61	222.0	COG0778@1|root,COG0778@2|Bacteria,1UY72@1239|Firmicutes,248YJ@186801|Clostridia,42KUP@68298|Syntrophomonadaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DPH1_k127_6981487_0	439481.Aboo_0612	2.464e-106	356.0	COG1311@1|root,arCOG04455@2157|Archaea,2XSUG@28890|Euryarchaeota,3F2GQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B,Metallophos
DPH1_k127_6991898_2	1236689.MMALV_10930	2.582e-42	170.0	COG0517@1|root,arCOG00601@2157|Archaea,2XT75@28890|Euryarchaeota,3F2MU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	cbs1	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_6991898_1	1254432.SCE1572_37155	1.849e-64	233.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,2Z31P@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
DPH1_k127_6991898_5	693661.Arcve_1047	5.984e-06	53.0	COG1369@1|root,arCOG01365@2157|Archaea,2Y7CZ@28890|Euryarchaeota,246I3@183980|Archaeoglobi	183980|Archaeoglobi	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp2	-	3.1.26.5	ko:K03537	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	RNase_P_Rpp14
DPH1_k127_6991898_3	368408.Tpen_1488	1.764e-26	119.0	COG0340@1|root,arCOG01940@2157|Archaea,2XQ93@28889|Crenarchaeota	28889|Crenarchaeota	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
DPH1_k127_6991898_0	593750.Metfor_1649	1.506e-312	1039.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG03042@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAN4@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DPH1_k127_6991898_4	673860.AciM339_1260	1.026e-25	115.0	COG2524@1|root,arCOG00610@2157|Archaea,2Y88Y@28890|Euryarchaeota,3F2VE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DPH1_k127_7019520_0	945713.IALB_3185	3.163e-141	460.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DPH1_k127_7019520_1	565033.GACE_1287	8.146e-53	203.0	COG1024@1|root,arCOG00239@2157|Archaea,2Y2NP@28890|Euryarchaeota,246M0@183980|Archaeoglobi	183980|Archaeoglobi	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
DPH1_k127_7075001_0	926560.KE387023_gene2481	2.181e-119	395.0	COG0667@1|root,COG0667@2|Bacteria,1WM4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DPH1_k127_7115579_0	1121405.dsmv_2622	1.366e-88	310.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42PZ6@68525|delta/epsilon subdivisions,2WKNQ@28221|Deltaproteobacteria,2MI1H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
DPH1_k127_7115579_1	523850.TON_1137	2.869e-29	125.0	COG1685@1|root,arCOG01025@2157|Archaea,2XUI2@28890|Euryarchaeota,243I7@183968|Thermococci	183968|Thermococci	E	shikimate kinase activity	aroK	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
DPH1_k127_7117385_2	86416.Clopa_0839	5.428e-17	93.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,2496J@186801|Clostridia,36VG5@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_7117385_1	1236689.MMALV_00410	7.396e-24	104.0	COG1698@1|root,arCOG04308@2157|Archaea,2XZVX@28890|Euryarchaeota,3F2TA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterised protein family (UPF0147)	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
DPH1_k127_7117385_0	593117.TGAM_1546	2.323e-26	117.0	COG1266@1|root,arCOG05750@2157|Archaea,2XTC5@28890|Euryarchaeota,24431@183968|Thermococci	183968|Thermococci	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DPH1_k127_7117385_3	747365.Thena_0464	8.932e-13	79.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,42FJG@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
DPH1_k127_7119842_0	290397.Adeh_0831	1.411e-105	347.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YU0C@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
DPH1_k127_7119842_3	1459636.NTE_01131	5.645e-24	106.0	COG5646@1|root,arCOG09457@2157|Archaea	2157|Archaea	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DPH1_k127_7119842_2	644282.Deba_1407	7.363e-25	110.0	COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Ribonuclease H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
DPH1_k127_7119842_1	717606.PaecuDRAFT_2033	1.413e-75	285.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_7119842_4	9361.ENSDNOP00000034538	0.000754	53.0	KOG3513@1|root,KOG3513@2759|Eukaryota,38C7V@33154|Opisthokonta,3B984@33208|Metazoa,3CS11@33213|Bilateria,486YA@7711|Chordata,496MP@7742|Vertebrata,3JCD7@40674|Mammalia	33208|Metazoa	T	positive regulation of axon extension	L1CAM	GO:0000003,GO:0000132,GO:0000226,GO:0000278,GO:0000902,GO:0000904,GO:0001101,GO:0001501,GO:0001558,GO:0001667,GO:0001932,GO:0002009,GO:0002064,GO:0002165,GO:0002252,GO:0002376,GO:0003007,GO:0003381,GO:0003382,GO:0003383,GO:0003384,GO:0003674,GO:0004888,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005886,GO:0005887,GO:0005911,GO:0005912,GO:0005913,GO:0005918,GO:0005919,GO:0006582,GO:0006725,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007010,GO:0007017,GO:0007043,GO:0007049,GO:0007154,GO:0007155,GO:0007156,GO:0007157,GO:0007158,GO:0007159,GO:0007160,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007173,GO:0007272,GO:0007275,GO:0007369,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007420,GO:0007424,GO:0007444,GO:0007507,GO:0007552,GO:0007560,GO:0007610,GO:0007617,GO:0007618,GO:0007619,GO:0008037,GO:0008038,GO:0008045,GO:0008049,GO:0008050,GO:0008092,GO:0008150,GO:0008152,GO:0008361,GO:0008366,GO:0009410,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010001,GO:0010033,GO:0010243,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010810,GO:0010811,GO:0010975,GO:0010976,GO:0012505,GO:0014070,GO:0014823,GO:0016020,GO:0016021,GO:0016043,GO:0016049,GO:0016319,GO:0016328,GO:0016358,GO:0016477,GO:0017154,GO:0018958,GO:0019098,GO:0019220,GO:0019222,GO:0019748,GO:0019904,GO:0019953,GO:0019991,GO:0021675,GO:0021682,GO:0021700,GO:0021782,GO:0022008,GO:0022402,GO:0022407,GO:0022409,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030010,GO:0030016,GO:0030017,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030155,GO:0030165,GO:0030175,GO:0030182,GO:0030307,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030506,GO:0030516,GO:0030673,GO:0030855,GO:0031099,GO:0031102,GO:0031103,GO:0031175,GO:0031224,GO:0031226,GO:0031252,GO:0031253,GO:0031256,GO:0031323,GO:0031344,GO:0031346,GO:0031399,GO:0031406,GO:0031410,GO:0031589,GO:0031960,GO:0031982,GO:0032101,GO:0032268,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032589,GO:0032590,GO:0032809,GO:0032870,GO:0032879,GO:0032989,GO:0032990,GO:0033267,GO:0033554,GO:0033563,GO:0033564,GO:0033627,GO:0033631,GO:0033691,GO:0033993,GO:0034109,GO:0034329,GO:0034330,GO:0035006,GO:0035010,GO:0035011,GO:0035150,GO:0035151,GO:0035152,GO:0035239,GO:0035295,GO:0035690,GO:0036094,GO:0036477,GO:0038023,GO:0038127,GO:0040001,GO:0040007,GO:0040008,GO:0040011,GO:0040012,GO:0042063,GO:0042074,GO:0042221,GO:0042325,GO:0042330,GO:0042440,GO:0042493,GO:0042734,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043195,GO:0043200,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043296,GO:0043297,GO:0043408,GO:0043621,GO:0043679,GO:0044085,GO:0044237,GO:0044292,GO:0044294,GO:0044295,GO:0044297,GO:0044298,GO:0044304,GO:0044306,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045087,GO:0045121,GO:0045202,GO:0045216,GO:0045471,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045785,GO:0045924,GO:0045927,GO:0046677,GO:0046872,GO:0048036,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048588,GO:0048589,GO:0048598,GO:0048609,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048675,GO:0048678,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048812,GO:0048813,GO:0048814,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050773,GO:0050775,GO:0050789,GO:0050793,GO:0050794,GO:0050808,GO:0050839,GO:0050848,GO:0050850,GO:0050896,GO:0050900,GO:0050920,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051270,GO:0051293,GO:0051294,GO:0051384,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0051960,GO:0051962,GO:0060089,GO:0060179,GO:0060180,GO:0060255,GO:0060284,GO:0060322,GO:0060429,GO:0060536,GO:0060541,GO:0060560,GO:0060562,GO:0060856,GO:0060857,GO:0061343,GO:0061387,GO:0061448,GO:0061564,GO:0065007,GO:0065008,GO:0070160,GO:0070161,GO:0070252,GO:0070372,GO:0070593,GO:0070848,GO:0070887,GO:0071229,GO:0071230,GO:0071236,GO:0071310,GO:0071361,GO:0071363,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071526,GO:0071542,GO:0071548,GO:0071549,GO:0071559,GO:0071560,GO:0071695,GO:0071704,GO:0071840,GO:0071944,GO:0072359,GO:0072499,GO:0080090,GO:0090066,GO:0097060,GO:0097066,GO:0097067,GO:0097068,GO:0097069,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:0097367,GO:0097447,GO:0097458,GO:0097485,GO:0097708,GO:0098552,GO:0098589,GO:0098590,GO:0098609,GO:0098742,GO:0098793,GO:0098805,GO:0098857,GO:0098858,GO:0099080,GO:0099081,GO:0099512,GO:0106030,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1900006,GO:1901360,GO:1901615,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533,GO:1902667,GO:1902850,GO:1903047,GO:1903859,GO:1904386,GO:1904387,GO:1990089,GO:1990090,GO:1990138,GO:2000026	-	ko:K06550,ko:K06756,ko:K06760	ko04360,ko04514,map04360,map04514	-	-	-	ko00000,ko00001,ko00537,ko04090,ko04091,ko04516	-	-	-	Bravo_FIGEY,I-set,Ig_3,fn3
DPH1_k127_715953_0	401053.AciPR4_1884	1.646e-20	100.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria,2JHKB@204432|Acidobacteriia	204432|Acidobacteriia	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_717423_0	439481.Aboo_0942	1.833e-206	666.0	COG0532@1|root,arCOG01560@2157|Archaea,2XU09@28890|Euryarchaeota,3F2FJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D4,IF-2,Intein_splicing,LAGLIDADG_3
DPH1_k127_717423_1	224325.AF_0767	1.634e-55	199.0	COG0105@1|root,arCOG04313@2157|Archaea,2XWSK@28890|Euryarchaeota,2465T@183980|Archaeoglobi	183980|Archaeoglobi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DPH1_k127_717423_6	224325.AF_0766	1.006e-22	98.0	COG2075@1|root,arCOG01950@2157|Archaea,2Y00Q@28890|Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl24e	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
DPH1_k127_717423_4	1054217.TALC_00113	1.968e-27	112.0	COG2053@1|root,arCOG04314@2157|Archaea,2XYMV@28890|Euryarchaeota,241VA@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	-	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
DPH1_k127_717423_2	1151117.AJLF01000001_gene890	1.547e-39	151.0	COG1358@1|root,arCOG01751@2157|Archaea,2XX4C@28890|Euryarchaeota,2444W@183968|Thermococci	183968|Thermococci	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
DPH1_k127_717423_8	797302.Halru_1965	1.374e-05	53.0	arCOG01917@1|root,arCOG10346@1|root,arCOG01917@2157|Archaea,arCOG10346@2157|Archaea	2157|Archaea	M	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zinc_ribbon_2
DPH1_k127_717423_3	415426.Hbut_1332	8.239e-39	155.0	COG0639@1|root,arCOG01143@2157|Archaea,2XQ9H@28889|Crenarchaeota	28889|Crenarchaeota	T	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2
DPH1_k127_717423_7	263820.PTO0507	1.653e-18	93.0	COG2151@1|root,arCOG01845@2157|Archaea,2Y0P6@28890|Euryarchaeota,242AR@183967|Thermoplasmata	183967|Thermoplasmata	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DPH1_k127_717423_5	589924.Ferp_0134	6.995e-25	112.0	COG3413@1|root,arCOG02271@2157|Archaea,2XU8X@28890|Euryarchaeota	28890|Euryarchaeota	K	Bacterio-opsin activator HTH domain-containing protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
DPH1_k127_7182147_0	1150399.AQYK01000002_gene3209	2.426e-29	137.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_7186568_0	357809.Cphy_2417	1.899e-64	230.0	COG0454@1|root,COG0456@2|Bacteria,1TYX1@1239|Firmicutes,24BZP@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DPH1_k127_7207130_2	94122.Shewana3_3368	8.07e-10	66.0	COG1846@1|root,COG1846@2|Bacteria,1QVN5@1224|Proteobacteria,1T2FF@1236|Gammaproteobacteria,2Q8T4@267890|Shewanellaceae	1236|Gammaproteobacteria	K	regulatory protein MarR	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,MarR,MarR_2
DPH1_k127_7207130_0	368408.Tpen_0334	8.406e-37	152.0	COG0639@1|root,arCOG01143@2157|Archaea,2XQS4@28889|Crenarchaeota	28889|Crenarchaeota	T	SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
DPH1_k127_7207130_1	880073.Calab_0825	6.114e-17	96.0	COG1404@1|root,COG3637@1|root,COG1404@2|Bacteria,COG3637@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	DUF3138,Peptidase_S8
DPH1_k127_7238924_0	351160.RCIX1783	6.629e-57	209.0	COG1620@1|root,arCOG04386@2157|Archaea	2157|Archaea	C	L-lactate permease	lctP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
DPH1_k127_7238924_1	1379698.RBG1_1C00001G1092	7.005e-48	193.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
DPH1_k127_7238924_2	273116.14325439	2.367e-28	117.0	COG1960@1|root,arCOG04310@2157|Archaea,2XXBZ@28890|Euryarchaeota,2426V@183967|Thermoplasmata	183967|Thermoplasmata	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_724502_2	30611.ENSOGAP00000000193	0.0006044	48.0	KOG1721@1|root,KOG1721@2759|Eukaryota,39T7Z@33154|Opisthokonta,3BMHB@33208|Metazoa,3D3DJ@33213|Bilateria,4874B@7711|Chordata,495J9@7742|Vertebrata,3JA7V@40674|Mammalia,35NZQ@314146|Euarchontoglires,4MC82@9443|Primates	33208|Metazoa	K	leucine rich region	ZNF500	GO:0000122,GO:0000981,GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070013,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K09229	-	-	-	-	ko00000,ko03000	-	-	-	KRAB,SCAN,zf-C2H2
DPH1_k127_724502_0	1041930.Mtc_1630	1.472e-51	204.0	COG2202@1|root,arCOG02353@1|root,arCOG02353@2157|Archaea,arCOG06515@2157|Archaea	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_724502_1	765910.MARPU_10645	7.251e-09	67.0	COG3829@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2SJ@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,Response_reg
DPH1_k127_7256429_5	673860.AciM339_0759	6.457e-49	185.0	COG1468@1|root,arCOG00786@2157|Archaea,2Y71A@28890|Euryarchaeota,3F34X@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	TIGRFAM CRISPR-associated protein Cas4	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PDDEXK_1
DPH1_k127_7256429_3	673860.AciM339_0766	5.192e-61	215.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,3F2RB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.7.1,1.2.7.7	ko:K00172,ko:K00189	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
DPH1_k127_7256429_6	768679.TTX_1784	3.729e-24	106.0	COG1144@1|root,arCOG01605@2157|Archaea,2XQW3@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
DPH1_k127_7256429_0	673860.AciM339_0764	4.996e-131	434.0	COG0674@1|root,arCOG01608@2157|Archaea,2XTB0@28890|Euryarchaeota,3F36A@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorA	-	1.2.7.1,1.2.7.7	ko:K00169,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DPH1_k127_7256429_1	439481.Aboo_0301	1.728e-119	391.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,3F2JH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorB	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DPH1_k127_7256429_9	69014.TK0691	5.233e-11	70.0	arCOG03805@1|root,arCOG03803@2157|Archaea,2Y30J@28890|Euryarchaeota,242VU@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
DPH1_k127_7256429_8	313596.RB2501_11797	4.562e-17	88.0	COG3832@1|root,COG3832@2|Bacteria,4NPKI@976|Bacteroidetes,1I28I@117743|Flavobacteriia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DPH1_k127_7256429_7	1134413.ANNK01000072_gene2843	1.975e-21	111.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,4HHPY@91061|Bacilli,1ZIDI@1386|Bacillus	91061|Bacilli	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
DPH1_k127_7256429_4	224325.AF_1728	4.827e-56	211.0	COG0438@1|root,arCOG01403@2157|Archaea,2XVAJ@28890|Euryarchaeota,245P8@183980|Archaeoglobi	183980|Archaeoglobi	M	Glycosyltransferase Family 4	-	-	2.4.1.87	ko:K00743	ko00601,map00601	-	R05978,R06169	-	ko00000,ko00001,ko01000,ko01003	-	GT6	-	Glyco_transf_4,Glycos_transf_1
DPH1_k127_7256429_2	565033.GACE_1114	1.053e-107	364.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,245ZX@183980|Archaeoglobi	183980|Archaeoglobi	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DPH1_k127_7281084_2	1041930.Mtc_1662	3.302e-58	221.0	arCOG04521@1|root,arCOG04521@2157|Archaea,2XUMG@28890|Euryarchaeota,2NAW2@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7281084_1	304371.MCP_1765	6.771e-75	262.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT2Y@28890|Euryarchaeota,2N9GE@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_7281084_0	439481.Aboo_1323	1.094e-86	297.0	COG1577@1|root,arCOG01028@2157|Archaea,2XSUB@28890|Euryarchaeota,3F2JQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
DPH1_k127_7360433_2	880073.Calab_2183	3.79e-11	77.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Calx-beta,DUF5122,Haemagg_act,HemolysinCabind,PPC,VCBS
DPH1_k127_7360433_5	324602.Caur_1238	0.0002539	55.0	COG2823@1|root,COG5297@1|root,COG2823@2|Bacteria,COG5297@2|Bacteria,2GA85@200795|Chloroflexi,376AG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7360433_3	68260.JOAY01000017_gene3476	1.09e-08	66.0	COG0500@1|root,COG2226@2|Bacteria,2I1M7@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DPH1_k127_7360433_0	1047013.AQSP01000081_gene96	8.223e-95	319.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DPH1_k127_7360433_1	797209.ZOD2009_00895	4.237e-12	77.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XWRN@28890|Euryarchaeota,23VH4@183963|Halobacteria	183963|Halobacteria	K	DNA binding	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	HTH_10
DPH1_k127_7360433_4	1132509.C447_03891	3.55e-05	51.0	COG1617@1|root,arCOG02197@2157|Archaea,2XXRY@28890|Euryarchaeota,23W8H@183963|Halobacteria	183963|Halobacteria	S	KEOPS complex Cgi121-like subunit	cgi121	-	-	ko:K09119	-	-	-	-	ko00000,ko03016	-	-	-	CGI-121
DPH1_k127_736384_0	439481.Aboo_1121	7.957e-124	405.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,3F2F5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1168	OTCace,OTCace_N
DPH1_k127_736384_1	439481.Aboo_1120	1.151e-38	161.0	COG1781@1|root,arCOG04229@2157|Archaea,2XWP4@28890|Euryarchaeota,3F2R2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
DPH1_k127_7384128_6	56110.Oscil6304_0577	2.178e-27	123.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,1G2F0@1117|Cyanobacteria,1HF0C@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DPH1_k127_7384128_2	224325.AF_1788	1.417e-50	194.0	COG0005@1|root,arCOG01327@2157|Archaea,2XUJX@28890|Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DPH1_k127_7384128_0	456442.Mboo_0768	1.161e-115	386.0	COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,2N91D@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent	dadD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DPH1_k127_7384128_3	673860.AciM339_0168	1.466e-50	186.0	COG0503@1|root,arCOG00030@2157|Archaea,2XTWM@28890|Euryarchaeota,3F2QV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	iAF692.Mbar_A1633	Pribosyltran
DPH1_k127_7384128_5	1232410.KI421426_gene1328	1.045e-38	159.0	COG0535@1|root,COG0535@2|Bacteria,1RADC@1224|Proteobacteria,43DPS@68525|delta/epsilon subdivisions,2X6SW@28221|Deltaproteobacteria,43TGW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
DPH1_k127_7384128_7	673860.AciM339_0628	2.389e-24	105.0	arCOG05238@1|root,arCOG05238@2157|Archaea,2Y0YG@28890|Euryarchaeota,3F3EA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7384128_1	673860.AciM339_1443	3.532e-115	390.0	COG0608@1|root,arCOG00427@2157|Archaea,2XT8Y@28890|Euryarchaeota,3F2FV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	recJ	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
DPH1_k127_7384128_4	926550.CLDAP_28350	6.172e-50	194.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
DPH1_k127_7404991_0	1047013.AQSP01000140_gene2469	1.246e-246	771.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DPH1_k127_7404991_1	1345697.M493_08290	1.88e-233	734.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1WEPJ@129337|Geobacillus	91061|Bacilli	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	iYO844.BSU18210	Carboxyl_trans
DPH1_k127_7404991_3	1120973.AQXL01000074_gene1036	1.566e-86	297.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,2790J@186823|Alicyclobacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
DPH1_k127_7404991_7	1408254.T458_17930	2.653e-20	91.0	COG1038@1|root,COG1038@2|Bacteria,1UIWR@1239|Firmicutes,4ISV0@91061|Bacilli,270FY@186822|Paenibacillaceae	91061|Bacilli	C	Biotin-requiring enzyme	yngHB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
DPH1_k127_7404991_2	1345697.M493_08270	1.372e-167	537.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1WEIT@129337|Geobacillus	91061|Bacilli	I	Biotin carboxylase C-terminal domain	yngH	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DPH1_k127_7404991_6	448385.sce2686	9.117e-32	136.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YU5N@29|Myxococcales	28221|Deltaproteobacteria	T	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
DPH1_k127_7404991_9	1123024.AUII01000004_gene1469	0.0003014	51.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_11,Methyltransf_12,Methyltransf_25,PP-binding
DPH1_k127_7404991_8	378806.STAUR_8259	8.22e-16	94.0	COG3391@1|root,COG4412@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CARDB,Peptidase_M30,VCBS
DPH1_k127_7404991_10	1284352.AOIG01000036_gene3394	0.0009136	54.0	COG4124@1|root,COG4124@2|Bacteria,1V0UJ@1239|Firmicutes,4HGW4@91061|Bacilli,26T9Y@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 26 family	celA7	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_3,CBM_35,Glyco_hydro_26,Glyco_hydro_44,fn3
DPH1_k127_7404991_4	1386089.N865_05350	3.774e-51	211.0	COG4733@1|root,COG4733@2|Bacteria,2I7XV@201174|Actinobacteria,4FK2V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DPH1_k127_7404991_5	471854.Dfer_2684	5.786e-32	137.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DPH1_k127_7433002_0	529709.PYCH_06990	5.507e-78	281.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,242SX@183968|Thermococci	183968|Thermococci	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DPH1_k127_7433002_1	439481.Aboo_0021	1.693e-27	125.0	COG1522@1|root,arCOG01580@2157|Archaea,2Y6YT@28890|Euryarchaeota,3F2Y0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7460417_0	1184251.TCELL_0821	0.0002256	53.0	COG1305@1|root,arCOG02165@2157|Archaea,2XRIK@28889|Crenarchaeota	28889|Crenarchaeota	E	transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DPH1_k127_7463124_0	1041930.Mtc_0662	1.513e-51	190.0	COG0468@1|root,arCOG00417@2157|Archaea,2XTI2@28890|Euryarchaeota,2N9KC@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange	radB	-	-	ko:K04484	-	-	-	-	ko00000,ko03400	-	-	-	Rad51
DPH1_k127_7463124_1	56780.SYN_02192	2.112e-43	171.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,2MQGJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	nucleic acid binding	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
DPH1_k127_7463124_2	693661.Arcve_1550	3.153e-20	93.0	COG0640@1|root,arCOG01683@2157|Archaea,2Y0SK@28890|Euryarchaeota,2476X@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DPH1_k127_7511638_3	1125863.JAFN01000001_gene1911	4.93e-05	57.0	COG0457@1|root,COG1018@1|root,COG0457@2|Bacteria,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7511638_2	646529.Desaci_4543	2.7e-21	111.0	COG2247@1|root,COG2372@1|root,COG5492@1|root,COG2247@2|Bacteria,COG2372@2|Bacteria,COG5492@2|Bacteria,1UIDD@1239|Firmicutes,25EIH@186801|Clostridia,264RK@186807|Peptococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,fn3
DPH1_k127_7511638_0	251221.35214774	1.009e-87	327.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
DPH1_k127_7511638_1	649831.L083_3335	5.079e-48	191.0	COG4733@1|root,COG4733@2|Bacteria,2I61V@201174|Actinobacteria,4DJUW@85008|Micromonosporales	201174|Actinobacteria	MU	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DPH1_k127_7513462_1	673860.AciM339_0321	1.398e-167	533.0	COG1697@1|root,arCOG04143@2157|Archaea,2XTNQ@28890|Euryarchaeota,3F2HT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
DPH1_k127_7513462_0	673860.AciM339_0322	1.615e-189	624.0	COG1389@1|root,arCOG01165@2157|Archaea,2XTZQ@28890|Euryarchaeota,3F2EU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
DPH1_k127_7513462_3	935557.ATYB01000008_gene5407	1.316e-09	73.0	COG2911@1|root,COG2911@2|Bacteria,1P8N9@1224|Proteobacteria,2TWRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
DPH1_k127_7513462_2	861299.J421_0120	4.979e-11	77.0	COG3291@1|root,COG3325@1|root,COG3291@2|Bacteria,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.1.3.5,3.2.1.14	ko:K01081,ko:K01183,ko:K20276	ko00230,ko00240,ko00520,ko00760,ko01100,ko01110,ko02024,map00230,map00240,map00520,map00760,map01100,map01110,map02024	-	R00183,R00511,R00963,R01126,R01206,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02334,R02719,R03346	RC00017,RC00467	ko00000,ko00001,ko01000	-	GH18	-	F5_F8_type_C,Glyco_hydro_18,NPCBM_assoc,PKD,PPC,Trypsin_2,fn3
DPH1_k127_7536961_1	246969.TAM4_180	1.322e-24	105.0	COG1831@1|root,arCOG00893@2157|Archaea,2XTX7@28890|Euryarchaeota,243FU@183968|Thermococci	183968|Thermococci	S	TatD related DNase	-	-	-	ko:K07049	-	-	-	-	ko00000	-	-	-	TatD_DNase
DPH1_k127_7536961_0	1236689.MMALV_01470	1.23e-92	312.0	COG0047@1|root,arCOG00102@2157|Archaea,2XTPA@28890|Euryarchaeota,3F2JR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2755	GATase_5
DPH1_k127_7536968_1	264732.Moth_2333	9.366e-21	96.0	COG1569@1|root,COG1569@2|Bacteria,1VCZ6@1239|Firmicutes,24Q32@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
DPH1_k127_7536968_2	69014.TK0888	1.283e-11	68.0	COG2002@1|root,arCOG00812@2157|Archaea,2Y6IB@28890|Euryarchaeota,244N0@183968|Thermococci	183968|Thermococci	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
DPH1_k127_7536968_0	1261545.MBE-HAL_0987	1.123e-100	344.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,23SS9@183963|Halobacteria	183963|Halobacteria	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
DPH1_k127_7542569_3	644282.Deba_2985	3.823e-27	119.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42R1T@68525|delta/epsilon subdivisions,2WN88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cysteine-rich domain	-	-	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
DPH1_k127_7542569_0	584708.Apau_0281	3.25e-39	151.0	COG0652@1|root,COG0652@2|Bacteria,3TBKH@508458|Synergistetes	508458|Synergistetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
DPH1_k127_7542569_2	1183377.Py04_0867	2.149e-31	133.0	COG0432@1|root,arCOG04214@2157|Archaea,2XXSW@28890|Euryarchaeota,2449A@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DPH1_k127_7542569_1	1147.D082_14820	2.43e-33	149.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
DPH1_k127_7548909_2	1236689.MMALV_10400	3.521e-34	138.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,3F2IJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22
DPH1_k127_7548909_1	795797.C497_10093	8.244e-78	276.0	COG0044@1|root,arCOG00689@2157|Archaea,2XTQU@28890|Euryarchaeota,23TFD@183963|Halobacteria	183963|Halobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3,3.5.2.5	ko:K01465,ko:K01466	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00051,M00546	R01993,R02425	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DPH1_k127_7548909_0	1054217.TALC_01079	1.21e-281	892.0	COG0525@1|root,arCOG00808@2157|Archaea,2XSXQ@28890|Euryarchaeota,241KT@183967|Thermoplasmata	183967|Thermoplasmata	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DPH1_k127_7549427_0	529709.PYCH_08260	9.625e-49	183.0	COG2519@1|root,arCOG00978@2157|Archaea,2XTV7@28890|Euryarchaeota,2439X@183968|Thermococci	183968|Thermococci	J	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
DPH1_k127_7549427_1	273116.14324441	3.776e-37	156.0	COG0477@1|root,arCOG00130@2157|Archaea,2Y8EG@28890|Euryarchaeota,2424M@183967|Thermoplasmata	183967|Thermoplasmata	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_7549427_2	589865.DaAHT2_1653	1.497e-33	133.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WMVB@28221|Deltaproteobacteria,2MQ2W@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DPH1_k127_7549802_0	1236689.MMALV_04840	1.85e-116	400.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota,3F2IG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TIGRFAM NiFe hydrogenase maturation protein HypF	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
DPH1_k127_7549802_1	593750.Metfor_0350	2.787e-75	259.0	COG0378@1|root,arCOG01231@2157|Archaea,2XUJS@28890|Euryarchaeota,2N9SQ@224756|Methanomicrobia	224756|Methanomicrobia	O	TIGRFAM hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
DPH1_k127_7549802_3	1242864.D187_000023	6.801e-19	99.0	29Z39@1|root,30M0T@2|Bacteria,1Q3Q8@1224|Proteobacteria,439HD@68525|delta/epsilon subdivisions,2X4TN@28221|Deltaproteobacteria,2YZK3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7549802_2	1158318.ATXC01000001_gene574	1.303e-35	140.0	COG0864@1|root,COG0864@2|Bacteria,2G47H@200783|Aquificae	200783|Aquificae	K	Transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
DPH1_k127_7563780_0	224325.AF_1424	1.991e-121	411.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,245T6@183980|Archaeoglobi	183980|Archaeoglobi	J	phenylalanyl-tRNA synthetase, beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
DPH1_k127_7563780_1	1232410.KI421417_gene2716	1.548e-118	394.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DPH1_k127_7563780_2	880073.Calab_0825	7.599e-38	166.0	COG1404@1|root,COG3637@1|root,COG1404@2|Bacteria,COG3637@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	DUF3138,Peptidase_S8
DPH1_k127_7592358_16	56110.Oscil6304_0755	7.44e-17	85.0	COG0517@1|root,COG0517@2|Bacteria,1G08K@1117|Cyanobacteria,1H9HG@1150|Oscillatoriales	1117|Cyanobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CP12
DPH1_k127_7592358_19	868131.MSWAN_1551	8.26e-05	55.0	COG4009@1|root,arCOG04905@2157|Archaea,2Y0I1@28890|Euryarchaeota,23P7W@183925|Methanobacteria	183925|Methanobacteria	S	Domain of unknown function (DUF749)	-	-	-	-	-	-	-	-	-	-	-	-	DUF749
DPH1_k127_7592358_6	267377.MMP1053	2.166e-101	337.0	COG2048@1|root,arCOG00338@2157|Archaea,2XTWJ@28890|Euryarchaeota,23Q3U@183939|Methanococci	183939|Methanococci	C	heterodisulfide reductase, subunit B	hdrB2	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DPH1_k127_7592358_14	1236689.MMALV_13670	6.321e-46	179.0	COG2048@1|root,arCOG00964@2157|Archaea,2XZ7E@28890|Euryarchaeota,3F2WA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
DPH1_k127_7592358_17	634498.mru_0249	2.442e-14	84.0	COG0583@1|root,arCOG00225@2157|Archaea,2XYM3@28890|Euryarchaeota,23P3T@183925|Methanobacteria	183925|Methanobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
DPH1_k127_7592358_2	647113.Metok_0186	3.174e-266	835.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
DPH1_k127_7592358_15	1054217.TALC_01277	2.698e-27	118.0	COG2048@1|root,arCOG00964@2157|Archaea,2XXYP@28890|Euryarchaeota	28890|Euryarchaeota	C	heterodisulfide reductase subunit C	hdrC1	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8,Fer4_9
DPH1_k127_7592358_8	267377.MMP1053	4.531e-80	278.0	COG2048@1|root,arCOG00338@2157|Archaea,2XTWJ@28890|Euryarchaeota,23Q3U@183939|Methanococci	183939|Methanococci	C	heterodisulfide reductase, subunit B	hdrB2	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DPH1_k127_7592358_11	429009.Adeg_2015	2.348e-50	197.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
DPH1_k127_7592358_1	387631.Asulf_01816	0.0	1031.0	COG1148@1|root,arCOG02234@2157|Archaea,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
DPH1_k127_7592358_13	429009.Adeg_2015	8.914e-48	191.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
DPH1_k127_7592358_7	335543.Sfum_1176	8.95e-98	340.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
DPH1_k127_7592358_4	647113.Metok_0186	1.385e-136	457.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
DPH1_k127_7592358_3	335543.Sfum_1179	1.921e-157	534.0	COG1148@1|root,COG1148@2|Bacteria,1PZ04@1224|Proteobacteria,42PT3@68525|delta/epsilon subdivisions,2WMJU@28221|Deltaproteobacteria,2MR5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
DPH1_k127_7592358_12	880072.Desac_0835	3.972e-48	182.0	COG1908@1|root,COG2512@1|root,COG1908@2|Bacteria,COG2512@2|Bacteria,1RCZY@1224|Proteobacteria,42TFE@68525|delta/epsilon subdivisions,2WPDR@28221|Deltaproteobacteria,2MRBM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
DPH1_k127_7592358_0	387631.Asulf_01816	0.0	1091.0	COG1148@1|root,arCOG02234@2157|Archaea,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
DPH1_k127_7592358_9	1236689.MMALV_03040	8.595e-62	216.0	COG1908@1|root,arCOG02475@2157|Archaea,2XY1E@28890|Euryarchaeota,3F2PR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Methyl-viologen-reducing hydrogenase, delta subunit	mvhD-2	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
DPH1_k127_7592358_18	335543.Sfum_1180	1.675e-10	69.0	COG1908@1|root,COG1908@2|Bacteria,1RDMH@1224|Proteobacteria,42RX1@68525|delta/epsilon subdivisions,2WNT8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CK	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD,HTH_5
DPH1_k127_7592358_5	1121422.AUMW01000038_gene3024	2.238e-111	374.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia,264VD@186807|Peptococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
DPH1_k127_7592358_10	1379698.RBG1_1C00001G0047	2.564e-53	190.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
DPH1_k127_7624245_2	69014.TK2264	6.11e-21	106.0	COG1800@1|root,arCOG07561@1|root,arCOG02164@2157|Archaea,arCOG07561@2157|Archaea,2XV3J@28890|Euryarchaeota,2435K@183968|Thermococci	183968|Thermococci	K	Transglutaminase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF553
DPH1_k127_7624245_3	439481.Aboo_0800	1.749e-17	89.0	arCOG13537@1|root,arCOG13537@2157|Archaea,2Y1U2@28890|Euryarchaeota,3F2T4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_7624245_1	591019.Shell_0491	8.663e-51	207.0	COG0515@1|root,COG2319@1|root,arCOG03270@1|root,arCOG02491@2157|Archaea,arCOG03270@2157|Archaea,arCOG03682@2157|Archaea,2XQUK@28889|Crenarchaeota	28889|Crenarchaeota	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DPH1_k127_7624245_0	391623.TERMP_00992	6.627e-101	333.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
DPH1_k127_7639764_0	1121926.AXWO01000027_gene314	1.833e-24	119.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4EY01@85014|Glycomycetales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DPH1_k127_771915_0	679926.Mpet_1134	7.029e-46	188.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,2NAXD@224756|Methanomicrobia	224756|Methanomicrobia	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DPH1_k127_771915_1	1168034.FH5T_01530	2.417e-17	88.0	COG1520@1|root,COG1520@2|Bacteria,4P310@976|Bacteroidetes	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DPH1_k127_7805048_0	1089551.KE386572_gene1743	2.383e-47	195.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria,4BRG6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_7826159_1	673860.AciM339_1575	3.037e-36	145.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota,3F328@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DPH1_k127_7826159_0	1121468.AUBR01000046_gene1901	1.725e-158	513.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,42FMG@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
DPH1_k127_7851269_0	593117.TGAM_2017	2.113e-56	209.0	COG1831@1|root,arCOG00893@2157|Archaea,2XTX7@28890|Euryarchaeota,243FU@183968|Thermococci	183968|Thermococci	S	TatD related DNase	-	-	-	ko:K07049	-	-	-	-	ko00000	-	-	-	TatD_DNase
DPH1_k127_7854408_3	1432050.IE4771_CH00832	0.0007876	47.0	COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,4BBH7@82115|Rhizobiaceae	28211|Alphaproteobacteria	U	protein with a C-terminal OMP (outer membrane protein) domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
DPH1_k127_7854408_0	1041930.Mtc_0138	2.024e-125	423.0	COG0018@1|root,arCOG00487@2157|Archaea,2XTWP@28890|Euryarchaeota,2N9C5@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DPH1_k127_7854408_1	368407.Memar_1351	4.693e-34	152.0	COG0642@1|root,arCOG06516@1|root,arCOG06192@2157|Archaea,arCOG06516@2157|Archaea	2157|Archaea	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DPH1_k127_7854408_2	1089553.Tph_c27620	5.179e-10	67.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,42EKW@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
DPH1_k127_7908508_1	673860.AciM339_0324	1.931e-08	66.0	COG0640@1|root,arCOG03408@1|root,arCOG01683@2157|Archaea,arCOG03409@2157|Archaea	2157|Archaea	K	PFAM Archaeal ATPase	birA	-	6.3.4.15	ko:K03524,ko:K06921	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	AAA_16,ATPase_2,BPL_C,BPL_LplA_LipB,HTH_11,TPR_12
DPH1_k127_7908508_0	6087.XP_002167697.2	7.985e-18	98.0	COG2373@1|root,KOG1366@2759|Eukaryota,38DGN@33154|Opisthokonta,3BCF2@33208|Metazoa	33208|Metazoa	O	endopeptidase inhibitor activity	A2ML1	GO:0000003,GO:0001101,GO:0001553,GO:0001868,GO:0001869,GO:0002020,GO:0002376,GO:0002437,GO:0002438,GO:0002526,GO:0002576,GO:0002673,GO:0002682,GO:0002683,GO:0002697,GO:0002698,GO:0002920,GO:0002921,GO:0003006,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005096,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0006955,GO:0007275,GO:0007548,GO:0007565,GO:0007566,GO:0007584,GO:0007596,GO:0007597,GO:0007599,GO:0008047,GO:0008150,GO:0008152,GO:0008406,GO:0008585,GO:0009605,GO:0009611,GO:0009719,GO:0009725,GO:0009790,GO:0009892,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010037,GO:0010466,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016043,GO:0016192,GO:0019222,GO:0019538,GO:0019838,GO:0019899,GO:0019955,GO:0019956,GO:0019958,GO:0019959,GO:0019966,GO:0022411,GO:0022414,GO:0022602,GO:0022607,GO:0022617,GO:0023051,GO:0030141,GO:0030154,GO:0030162,GO:0030198,GO:0030234,GO:0030414,GO:0030449,GO:0030695,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031347,GO:0031348,GO:0031410,GO:0031667,GO:0031960,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032940,GO:0033993,GO:0034694,GO:0034695,GO:0034774,GO:0042060,GO:0042221,GO:0042493,GO:0042698,GO:0042802,GO:0042803,GO:0043062,GO:0043085,GO:0043086,GO:0043087,GO:0043120,GO:0043121,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043547,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044238,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0044877,GO:0045055,GO:0045088,GO:0045137,GO:0045824,GO:0045861,GO:0045916,GO:0046545,GO:0046660,GO:0046903,GO:0046983,GO:0048306,GO:0048403,GO:0048406,GO:0048511,GO:0048513,GO:0048519,GO:0048523,GO:0048545,GO:0048568,GO:0048583,GO:0048585,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0048863,GO:0048869,GO:0050727,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050817,GO:0050878,GO:0050896,GO:0051056,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0051345,GO:0051346,GO:0051384,GO:0051704,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060589,GO:0061134,GO:0061135,GO:0061458,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070542,GO:0070613,GO:0071704,GO:0071840,GO:0072347,GO:0072376,GO:0072378,GO:0080090,GO:0080134,GO:0097305,GO:0097708,GO:0098772,GO:0099503,GO:1901564,GO:1901654,GO:1901700,GO:1902531,GO:1903317,GO:1903318,GO:1990402,GO:2000257,GO:2000258	-	ko:K03910	ko04610,map04610	-	-	-	ko00000,ko00001,ko04131,ko04147	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
DPH1_k127_7941355_0	456442.Mboo_2190	1.832e-56	211.0	COG1478@1|root,arCOG02714@2157|Archaea,2XXJZ@28890|Euryarchaeota,2N9JQ@224756|Methanomicrobia	224756|Methanomicrobia	H	TIGRFAM F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
DPH1_k127_7971148_0	59374.Fisuc_0063	6.303e-12	79.0	COG2911@1|root,COG4254@1|root,COG2911@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	lgt	-	-	ko:K09800,ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001,ko02000	-	-	-	FecR
DPH1_k127_7984198_0	397278.JOJN01000019_gene2333	6.166e-20	104.0	COG2132@1|root,COG2133@1|root,COG2982@1|root,COG3291@1|root,COG3401@1|root,COG4733@1|root,COG2132@2|Bacteria,COG2133@2|Bacteria,COG2982@2|Bacteria,COG3291@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PA14
DPH1_k127_8083134_0	1121430.JMLG01000004_gene963	1.438e-107	355.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DPH1_k127_8083134_1	1232410.KI421428_gene1052	2.479e-101	353.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,42Q04@68525|delta/epsilon subdivisions,2WKF7@28221|Deltaproteobacteria,43S5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Transketolase, pyrimidine binding domain	tklB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DPH1_k127_8083134_2	864565.HMPREF0379_0991	5.012e-92	309.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DPH1_k127_8083134_3	306281.AJLK01000180_gene5325	1.161e-38	164.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1JJWZ@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_2,TPR_8
DPH1_k127_8098032_0	717606.PaecuDRAFT_2136	4.468e-35	151.0	COG1520@1|root,COG3210@1|root,COG4412@1|root,COG5276@1|root,COG5492@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG4412@2|Bacteria,COG5276@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
DPH1_k127_8099641_0	1121430.JMLG01000002_gene1327	4.898e-263	825.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DPH1_k127_8160072_0	342949.PNA2_0051	8.462e-117	401.0	COG1293@1|root,arCOG01695@2157|Archaea,2XTMF@28890|Euryarchaeota,243BD@183968|Thermococci	183968|Thermococci	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
DPH1_k127_8177368_0	889378.Spiaf_0758	8.565e-86	299.0	COG0452@1|root,COG0452@2|Bacteria,2J5EB@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DPH1_k127_8177368_1	413816.BBJP01000018_gene1311	5.846e-22	111.0	COG1829@1|root,arCOG04263@2157|Archaea,2XST6@28890|Euryarchaeota,23SPN@183963|Halobacteria	183963|Halobacteria	S	kinase, sugar kinase superfamily	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_N
DPH1_k127_8179319_3	1042877.GQS_02290	6.758e-31	131.0	COG2178@1|root,arCOG04318@2157|Archaea,2XYD0@28890|Euryarchaeota,242PY@183968|Thermococci	183968|Thermococci	J	Translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
DPH1_k127_8179319_2	224325.AF_2298	9.545e-76	265.0	COG1467@1|root,arCOG04110@2157|Archaea,2Y7DK@28890|Euryarchaeota,246SV@183980|Archaeoglobi	183980|Archaeoglobi	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8179319_0	909663.KI867150_gene2868	0.0	1021.0	COG0369@1|root,COG1151@2|Bacteria,1NRXN@1224|Proteobacteria,42Y5Y@68525|delta/epsilon subdivisions,2WUG6@28221|Deltaproteobacteria,2MSJ9@213462|Syntrophobacterales	2|Bacteria	P	Prismane/CO dehydrogenase family	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
DPH1_k127_8179319_1	439481.Aboo_1103	1.544e-140	469.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,3F2ID@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	helicase superfamily c-terminal domain	hef	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C,ResIII
DPH1_k127_8186543_0	693661.Arcve_0149	2.406e-14	87.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_8186543_1	1396141.BATP01000003_gene4864	2.579e-06	61.0	COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	2|Bacteria	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	oprH	-	3.2.1.4,3.2.1.73	ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449	ko00500,ko01100,ko05133,map00500,map01100,map05133	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko02000	1.B.14,1.B.14.2,1.B.40.2	GH5,GH9	-	Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3
DPH1_k127_8261897_1	1042877.GQS_04200	8.36e-40	162.0	arCOG11292@1|root,arCOG11292@2157|Archaea,2Y3FT@28890|Euryarchaeota,2443S@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8261897_0	1457250.BBMO01000001_gene1581	2.468e-43	181.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_8261897_2	243232.MJ_1172	4.452e-08	57.0	arCOG05071@1|root,arCOG05071@2157|Archaea,2Y0VX@28890|Euryarchaeota,23R7D@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF2683)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2683
DPH1_k127_8261897_3	252305.OB2597_03943	1.558e-07	65.0	COG2911@1|root,COG2931@1|root,COG4932@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2PF86@252301|Oceanicola	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HCBP_related,He_PIG,HemolysinCabind
DPH1_k127_8275722_1	673860.AciM339_0076	1.281e-66	239.0	COG1571@1|root,arCOG01115@2157|Archaea,2XTGD@28890|Euryarchaeota,3F2IS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743,tRNA_anti-codon
DPH1_k127_8275722_2	1054217.TALC_00178	5.393e-38	151.0	arCOG03678@1|root,arCOG03678@2157|Archaea,2XZ63@28890|Euryarchaeota,241VC@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8275722_0	1236689.MMALV_01670	5.152e-128	436.0	COG1199@1|root,arCOG00770@2157|Archaea,2XTH2@28890|Euryarchaeota,3F2IN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	HELICc2	rad3b	-	3.6.4.12	ko:K03722,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD_2,HBB,Helicase_C_2,ResIII
DPH1_k127_8275722_3	56780.SYN_01577	5.1e-11	70.0	COG1945@1|root,COG1945@2|Bacteria,1RE9E@1224|Proteobacteria,42RQ0@68525|delta/epsilon subdivisions,2WNKW@28221|Deltaproteobacteria,2MRSR@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
DPH1_k127_8290245_0	406124.ACPC01000017_gene625	6.851e-72	278.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
DPH1_k127_8342668_4	981369.JQMJ01000004_gene1018	3.748e-07	64.0	COG3291@1|root,COG3291@2|Bacteria,2HHTF@201174|Actinobacteria,2NHQJ@228398|Streptacidiphilus	201174|Actinobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Phosphoesterase,fn3
DPH1_k127_8342668_3	1453501.JELR01000002_gene104	1.049e-08	70.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,4672D@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glyco_18	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ
DPH1_k127_8342668_2	1313421.JHBV01000015_gene5729	5.794e-14	87.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Gram_pos_anchor
DPH1_k127_8342668_1	439481.Aboo_0014	2.618e-15	90.0	arCOG02780@1|root,arCOG02780@2157|Archaea,2Y714@28890|Euryarchaeota,3F34G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8342668_0	1501230.ET33_07355	2.645e-37	150.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HC2G@91061|Bacilli,26R4Z@186822|Paenibacillaceae	91061|Bacilli	S	MgtC SapB transporter	mgtC3	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
DPH1_k127_8342668_5	10224.XP_006822779.1	0.0005763	52.0	28IWW@1|root,2QR8M@2759|Eukaryota,38G0N@33154|Opisthokonta,3BCJK@33208|Metazoa,3CUA0@33213|Bilateria	33208|Metazoa	S	negative regulation of dendrite development	KIAA0319L	GO:0001764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0006928,GO:0007275,GO:0007399,GO:0008150,GO:0009987,GO:0010721,GO:0010975,GO:0010977,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016477,GO:0022008,GO:0030135,GO:0030136,GO:0030154,GO:0030659,GO:0030662,GO:0030665,GO:0031090,GO:0031344,GO:0031345,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0040011,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0048519,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051129,GO:0051179,GO:0051239,GO:0051241,GO:0051674,GO:0051960,GO:0051961,GO:0060284,GO:0061024,GO:0065007,GO:0071840,GO:0071944,GO:0097708,GO:0098588,GO:0098805,GO:0120035,GO:2000026,GO:2000171	-	-	-	-	-	-	-	-	-	-	REJ
DPH1_k127_8359423_3	926560.KE387027_gene350	2.321e-62	225.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_8359423_0	1236689.MMALV_00330	4.023e-169	535.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,3F2FH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DPH1_k127_8359423_4	1236689.MMALV_14300	3.618e-45	175.0	arCOG04990@1|root,arCOG04990@2157|Archaea,2XYVI@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function TPD sequence-motif	-	-	-	-	-	-	-	-	-	-	-	-	TPD
DPH1_k127_8359423_1	673860.AciM339_0533	2.55e-83	293.0	COG1746@1|root,arCOG04249@2157|Archaea,2XT5J@28890|Euryarchaeota,3F2HM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
DPH1_k127_8359423_6	263820.PTO0349	1.848e-06	59.0	arCOG02206@1|root,arCOG02206@2157|Archaea,2Y10D@28890|Euryarchaeota,242AI@183967|Thermoplasmata	183967|Thermoplasmata	S	ribosomal small subunit binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8359423_2	1151117.AJLF01000002_gene499	6.514e-71	246.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,24332@183968|Thermococci	183968|Thermococci	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
DPH1_k127_8359423_5	246969.TAM4_1610	4.728e-07	59.0	arCOG03797@1|root,arCOG03797@2157|Archaea,2Y3GC@28890|Euryarchaeota,2444Z@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
DPH1_k127_8397_0	1047013.AQSP01000125_gene2640	3.527e-126	415.0	COG2211@1|root,COG2211@2|Bacteria,2NPEZ@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
DPH1_k127_8397_2	688246.Premu_2183	5.27e-05	58.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes	976|Bacteroidetes	P	COG3420 Nitrous oxidase accessory protein	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DPH1_k127_8397_1	485918.Cpin_4113	2.781e-36	161.0	COG2911@1|root,COG2911@2|Bacteria,4NHHA@976|Bacteroidetes,1IVM6@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG
DPH1_k127_8427584_0	926569.ANT_09540	1.379e-25	119.0	COG1361@1|root,COG1721@1|root,COG1361@2|Bacteria,COG1721@2|Bacteria,2G7JJ@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DPH1_k127_8444101_0	118168.MC7420_4088	3.062e-05	58.0	COG2152@1|root,COG2152@2|Bacteria,1GCHI@1117|Cyanobacteria	1117|Cyanobacteria	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8444101_1	102129.Lepto7375DRAFT_0842	0.0002106	55.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,1G4UG@1117|Cyanobacteria,1HH6U@1150|Oscillatoriales	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
DPH1_k127_8466576_2	387092.NIS_0020	2.05e-20	102.0	COG0725@1|root,COG0725@2|Bacteria,1QD9D@1224|Proteobacteria,42QRE@68525|delta/epsilon subdivisions,2YQ3W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
DPH1_k127_8466576_0	439481.Aboo_0520	5.949e-86	291.0	COG0463@1|root,arCOG00894@2157|Archaea,2XUJ6@28890|Euryarchaeota,3F38U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DPH1_k127_8466576_3	1047013.AQSP01000052_gene2591	3.38e-07	58.0	COG1933@1|root,COG1933@2|Bacteria,2NRP4@2323|unclassified Bacteria	2|Bacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
DPH1_k127_8466576_1	694429.Pyrfu_0049	1.413e-23	111.0	COG0618@1|root,arCOG01565@2157|Archaea,2XQUB@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
DPH1_k127_8473368_0	1461693.ATO10_05417	1.347e-14	89.0	COG2911@1|root,COG2911@2|Bacteria,1P8N9@1224|Proteobacteria,2TXN3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_3,DUF4347
DPH1_k127_8516204_0	28072.Nos7524_5484	2.318e-28	133.0	COG2304@1|root,COG3209@1|root,COG3210@1|root,COG3266@1|root,COG5276@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG5276@2|Bacteria,1G4UG@1117|Cyanobacteria	1117|Cyanobacteria	M	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
DPH1_k127_8534635_4	1297742.A176_01260	3.342e-23	117.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36,Peptidase_M6
DPH1_k127_8534635_0	1469613.JT55_13250	1.396e-84	315.0	2F03P@1|root,33T7B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8534635_2	1030157.AFMP01000007_gene3148	5.123e-26	118.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2TQZQ@28211|Alphaproteobacteria,2K3T3@204457|Sphingomonadales	204457|Sphingomonadales	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DPH1_k127_8534635_5	1318628.MARLIPOL_09971	4.897e-07	63.0	COG1372@1|root,COG1520@1|root,COG3209@1|root,COG1372@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,46DDZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	LM	Rhs Family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF5122,He_PIG,PT-HINT,RHS_repeat
DPH1_k127_8534635_1	247490.KSU1_C0244	8.142e-37	161.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF285,DUF5011,PKD,SBBP,UnbV_ASPIC,VCBS,fn3
DPH1_k127_8534635_3	1227487.C474_14344	6.731e-24	112.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XVHG@28890|Euryarchaeota,23SZN@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	HTH_10
DPH1_k127_8535218_2	1125863.JAFN01000001_gene60	0.0005221	45.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CBM9_1,CBM_4_9,Cellulase,DUF285,Glyco_hydro_10,SLH,VCBS,fn3
DPH1_k127_8535218_0	304371.MCP_0066	3.114e-20	105.0	COG1497@1|root,arCOG04399@2157|Archaea,2XU16@28890|Euryarchaeota,2N9I6@224756|Methanomicrobia	224756|Methanomicrobia	K	SMART regulatory protein, Crp	-	-	-	ko:K07730	-	-	-	-	ko00000,ko03000	-	-	-	HTH_24,MarR_2
DPH1_k127_8535218_1	1041930.Mtc_0184	7.624e-20	104.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota	28890|Euryarchaeota	T	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DPH1_k127_853763_1	1236689.MMALV_00360	2.762e-41	163.0	COG0041@1|root,arCOG02464@2157|Archaea,2XU0P@28890|Euryarchaeota,3F2PJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DPH1_k127_853763_2	443143.GM18_0566	2.61e-06	62.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
DPH1_k127_853763_0	264732.Moth_0009	6.029e-94	312.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,42EVS@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
DPH1_k127_8544347_2	765420.OSCT_1615	2.91e-06	60.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi,375V5@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial Ig-like domain	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M_N,A2M_N_2,Big_5
DPH1_k127_8544347_0	266117.Rxyl_0085	6.45e-18	92.0	COG0723@1|root,COG0723@2|Bacteria,2HGHS@201174|Actinobacteria,4CTW3@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
DPH1_k127_8544347_1	1333523.L593_03300	5.064e-08	59.0	arCOG04596@1|root,arCOG04596@2157|Archaea,2XX20@28890|Euryarchaeota,23VPS@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8574227_0	439481.Aboo_0197	1.026e-263	849.0	COG0640@1|root,COG1201@1|root,arCOG00394@2157|Archaea,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,3F2IQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DEAD/H associated	lhr2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DPH1_k127_8590268_1	1227484.C471_07495	4.994e-32	145.0	COG2132@1|root,COG3291@1|root,arCOG11135@1|root,arCOG02546@2157|Archaea,arCOG03914@2157|Archaea,arCOG11135@2157|Archaea,2XZZB@28890|Euryarchaeota,23Y8X@183963|Halobacteria	183963|Halobacteria	Q	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DPH1_k127_8590268_0	273075.Ta0469	8.837e-139	452.0	COG0499@1|root,arCOG04137@2157|Archaea,2XT4S@28890|Euryarchaeota,241J8@183967|Thermoplasmata	183967|Thermoplasmata	F	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DPH1_k127_8616361_3	500153.JOEK01000006_gene5401	8.843e-07	53.0	COG2133@1|root,COG3291@1|root,COG3506@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1349,GSDH,PKD,ThuA
DPH1_k127_8616361_4	572546.Arcpr_0300	0.0003288	50.0	COG3291@1|root,arCOG03259@2157|Archaea,arCOG03396@2157|Archaea,2Y2R2@28890|Euryarchaeota,246MP@183980|Archaeoglobi	183980|Archaeoglobi	M	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,Prenyltrans
DPH1_k127_8616361_1	485916.Dtox_1966	4.532e-45	175.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,2616E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
DPH1_k127_8616361_0	760568.Desku_2237	2.789e-99	349.0	COG0488@1|root,COG0488@2|Bacteria,1UI2R@1239|Firmicutes,25EBF@186801|Clostridia,267CI@186807|Peptococcaceae	186801|Clostridia	S	PFAM ABC transporter related	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
DPH1_k127_8616361_2	555079.Toce_0351	3.69e-44	176.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,42G75@68295|Thermoanaerobacterales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
DPH1_k127_8620582_1	1396141.BATP01000022_gene486	2.634e-09	72.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
DPH1_k127_8620582_0	1144275.COCOR_01698	4.461e-22	114.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,Collagen,DUF4347,FG-GAP,He_PIG,HemolysinCabind,TIG,VCBS
DPH1_k127_8635824_2	525903.Taci_0034	1.284e-08	57.0	COG0524@1|root,COG0524@2|Bacteria,3TAXC@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DPH1_k127_8635824_1	1118054.CAGW01000061_gene2351	1.149e-59	217.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,4HBPD@91061|Bacilli	91061|Bacilli	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	ApbA,ApbA_C
DPH1_k127_8635824_0	388739.RSK20926_00655	1.067e-75	263.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,2P58I@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	mdeA	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
DPH1_k127_8650352_1	926550.CLDAP_28350	1.771e-37	160.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
DPH1_k127_8650352_0	1236689.MMALV_00620	9.953e-52	197.0	COG0558@1|root,arCOG00670@2157|Archaea,2XWJ0@28890|Euryarchaeota,3F2ME@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.39,2.7.8.5	ko:K00995,ko:K17884	ko00564,ko01100,map00564,map01100	-	R01801,R10464	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A1250	CDP-OH_P_transf
DPH1_k127_8650352_2	272844.PAB0757	8.177e-24	108.0	COG1936@1|root,arCOG01038@2157|Archaea,2XX2A@28890|Euryarchaeota,242QS@183968|Thermococci	183968|Thermococci	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
DPH1_k127_8663997_1	243231.GSU2914	2.475e-26	127.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,43C5A@68525|delta/epsilon subdivisions,2WNBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8663997_0	1054217.TALC_00658	1.381e-212	677.0	COG1245@1|root,arCOG00187@2157|Archaea,2XSZE@28890|Euryarchaeota,241KJ@183967|Thermoplasmata	183967|Thermoplasmata	E	Possible Fer4-like domain in RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
DPH1_k127_8663997_2	673860.AciM339_0905	3.489e-08	61.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DPH1_k127_8697502_0	1120973.AQXL01000114_gene713	3.141e-296	933.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,2783E@186823|Alicyclobacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DPH1_k127_8769551_4	679926.Mpet_0861	1.507e-10	75.0	COG3398@1|root,arCOG02611@2157|Archaea	679926.Mpet_0861|-	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8769551_1	493475.GARC_4265	2.014e-24	123.0	COG2931@1|root,COG2982@1|root,COG4733@1|root,COG2931@2|Bacteria,COG2982@2|Bacteria,COG4733@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS
DPH1_k127_8769551_6	102129.Lepto7375DRAFT_0842	6.707e-07	64.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,1G4UG@1117|Cyanobacteria,1HH6U@1150|Oscillatoriales	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
DPH1_k127_8769551_0	673860.AciM339_1234	3.011e-30	138.0	COG0361@1|root,arCOG01179@2157|Archaea,2XXX0@28890|Euryarchaeota,3F2RM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	eif1a	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
DPH1_k127_8769551_3	935866.JAER01000003_gene1293	2.159e-12	81.0	COG4932@1|root,COG4932@2|Bacteria,2I2ZN@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
DPH1_k127_8769551_5	1236689.MMALV_06090	3.791e-07	59.0	arCOG05357@1|root,arCOG05357@2157|Archaea,2Y1B1@28890|Euryarchaeota,3F2VN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8769551_2	9778.XP_004375522.1	3.457e-14	78.0	KOG0613@1|root,KOG4475@1|root,KOG0613@2759|Eukaryota,KOG4475@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata,48Y8I@7742|Vertebrata,3J1H6@40674|Mammalia,353MU@311790|Afrotheria	33208|Metazoa	T	Titin Z	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
DPH1_k127_8787833_1	1297742.A176_00747	4.09e-11	76.0	COG1372@1|root,COG2911@1|root,COG3209@1|root,COG1372@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,1PEID@1224|Proteobacteria,438II@68525|delta/epsilon subdivisions,2X3TD@28221|Deltaproteobacteria,2YX2B@29|Myxococcales	28221|Deltaproteobacteria	LM	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8787833_0	452637.Oter_3066	1.659e-23	119.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DctA-YdbH
DPH1_k127_8814931_1	269797.Mbar_A1433	4.542e-19	101.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTGJ@28890|Euryarchaeota,2N9QC@224756|Methanomicrobia	224756|Methanomicrobia	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
DPH1_k127_8814931_2	439481.Aboo_0587	0.0003034	50.0	COG2034@1|root,arCOG02717@2157|Archaea,2XZVB@28890|Euryarchaeota,3F3HD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF131	-	-	-	-	-	-	-	-	-	-	-	-	DUF131
DPH1_k127_8814931_0	439481.Aboo_0094	5.894e-193	632.0	COG0143@1|root,arCOG00810@2157|Archaea,2XTG5@28890|Euryarchaeota,3F2F7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A0543	Anticodon_1,tRNA-synt_1g,tRNA_bind
DPH1_k127_883724_0	545694.TREPR_2444	5.442e-228	727.0	COG3808@1|root,COG3808@2|Bacteria,2J6RD@203691|Spirochaetes	203691|Spirochaetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DPH1_k127_883724_2	273116.14324255	5.474e-08	59.0	arCOG05352@1|root,arCOG05352@2157|Archaea,2Y4MS@28890|Euryarchaeota,242C9@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_883724_1	1054217.TALC_01526	1.836e-19	96.0	COG0640@1|root,arCOG05349@2157|Archaea,2XYUG@28890|Euryarchaeota,241TE@183967|Thermoplasmata	183967|Thermoplasmata	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8854008_1	33876.JNXY01000033_gene2309	1e-16	91.0	COG0382@1|root,COG0382@2|Bacteria,2IJV5@201174|Actinobacteria,4DGXV@85008|Micromonosporales	201174|Actinobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
DPH1_k127_8854008_0	552811.Dehly_0435	3.519e-57	223.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
DPH1_k127_8870085_0	981383.AEWH01000063_gene1899	1.446e-17	98.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8
DPH1_k127_8879888_0	880071.Fleli_2410	3.695e-23	113.0	COG5492@1|root,COG5492@2|Bacteria,4PAER@976|Bacteroidetes,47TE8@768503|Cytophagia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8913278_0	1227454.C446_00425	5.803e-157	513.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,23RXX@183963|Halobacteria	183963|Halobacteria	O	COG0464 ATPases of the AAA class	cdc48a	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
DPH1_k127_8913278_3	1041930.Mtc_0083	3.153e-43	180.0	COG0619@1|root,arCOG02250@2157|Archaea,2Y0D5@28890|Euryarchaeota,2NAR1@224756|Methanomicrobia	224756|Methanomicrobia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
DPH1_k127_8913278_1	1041930.Mtc_0084	6.232e-101	346.0	COG1123@1|root,arCOG00185@2157|Archaea,2Y7PM@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC transporter	-	-	-	ko:K00400,ko:K16786,ko:K16787	ko00680,ko01100,ko01120,ko02010,map00680,map01100,map01120,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
DPH1_k127_8913278_2	351160.LRC325	3.425e-45	182.0	COG2041@1|root,arCOG00266@2157|Archaea	2157|Archaea	P	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	ABC_cobalt,Oxidored_molyb
DPH1_k127_8913278_4	1183377.Py04_1075	3.089e-22	106.0	arCOG03142@1|root,arCOG03142@2157|Archaea,2XTSE@28890|Euryarchaeota,242JN@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8920523_5	439481.Aboo_0536	2.253e-14	74.0	COG0371@1|root,arCOG00982@2157|Archaea,2XT0F@28890|Euryarchaeota,3F2IT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
DPH1_k127_8920523_4	1236689.MMALV_01400	4.98e-26	112.0	COG1849@1|root,arCOG01224@2157|Archaea,2XYS0@28890|Euryarchaeota,3F2SZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF357)	-	-	-	ko:K09728	-	-	-	-	ko00000	-	-	-	DUF357
DPH1_k127_8920523_1	673860.AciM339_1197	3.623e-128	427.0	COG0433@1|root,arCOG00280@2157|Archaea,2Y7MA@28890|Euryarchaeota,3F30Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
DPH1_k127_8920523_3	5888.CAK91022	4.27e-32	135.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
DPH1_k127_8920523_2	1094980.Mpsy_2342	4.48e-40	168.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	gvpD	-	-	-	-	-	-	-	-	-	-	-	GvpD
DPH1_k127_8920523_0	351160.RCIX231	3.016e-177	581.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,2N90P@224756|Methanomicrobia	224756|Methanomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DPH1_k127_8970912_6	215803.DB30_5453	4.772e-31	144.0	COG1372@1|root,COG2911@1|root,COG3209@1|root,COG3391@1|root,COG1372@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1PEID@1224|Proteobacteria,438II@68525|delta/epsilon subdivisions,2X3TD@28221|Deltaproteobacteria,2YX2B@29|Myxococcales	28221|Deltaproteobacteria	LM	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8970912_11	419665.Maeo_0963	2.819e-13	74.0	COG2923@1|root,arCOG02069@2157|Archaea	2157|Archaea	P	protein involved in the oxidation of intracellular sulfur	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
DPH1_k127_8970912_8	419665.Maeo_0964	6.509e-27	116.0	COG1553@1|root,arCOG02068@2157|Archaea,2Y0VW@28890|Euryarchaeota	28890|Euryarchaeota	P	DsrE/DsrF-like family	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
DPH1_k127_8970912_12	1123399.AQVE01000035_gene3179	3.059e-06	53.0	COG2168@1|root,COG2168@2|Bacteria,1PCBS@1224|Proteobacteria,1SX9A@1236|Gammaproteobacteria,46345@72273|Thiotrichales	72273|Thiotrichales	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
DPH1_k127_8970912_3	1220534.B655_0825	1.27e-51	189.0	COG0822@1|root,arCOG02077@2157|Archaea,2XX32@28890|Euryarchaeota,23PMF@183925|Methanobacteria	183925|Methanobacteria	C	Fe-S cluster	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DPH1_k127_8970912_0	1220534.B655_0826	1.429e-139	454.0	COG1104@1|root,arCOG00066@2157|Archaea,2Y7J8@28890|Euryarchaeota,23NPK@183925|Methanobacteria	183925|Methanobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DPH1_k127_8970912_10	439481.Aboo_0838	3.865e-15	81.0	arCOG05345@1|root,arCOG05345@2157|Archaea,2Y117@28890|Euryarchaeota,3F3G9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_8970912_9	1380394.JADL01000004_gene5737	2.19e-26	123.0	COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria,2TUBJ@28211|Alphaproteobacteria,2JPTM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DPH1_k127_8970912_7	453591.Igni_0451	2.437e-27	116.0	COG2058@1|root,arCOG04287@2157|Archaea,2XQSC@28889|Crenarchaeota	28889|Crenarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
DPH1_k127_8970912_2	1054217.TALC_00043	2.141e-75	265.0	COG0244@1|root,arCOG04288@2157|Archaea,2XU7C@28890|Euryarchaeota,241SB@183967|Thermoplasmata	183967|Thermoplasmata	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DPH1_k127_8970912_1	439481.Aboo_0862	1.068e-84	285.0	COG0081@1|root,arCOG04289@2157|Archaea,2XTJF@28890|Euryarchaeota,3F2IX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DPH1_k127_8970912_4	647113.Metok_0540	2.646e-49	180.0	COG0080@1|root,arCOG04372@2157|Archaea,2XTJN@28890|Euryarchaeota,23QV5@183939|Methanococci	183939|Methanococci	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DPH1_k127_8970912_5	351160.LRC28	2.287e-41	157.0	COG0250@1|root,arCOG01920@2157|Archaea,2XWGQ@28890|Euryarchaeota,2N9MV@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
DPH1_k127_8975166_1	926550.CLDAP_29090	1.172e-08	63.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
DPH1_k127_8975166_0	247490.KSU1_C0443	1.247e-157	521.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
DPH1_k127_8989822_2	103733.JNYO01000070_gene3646	1.271e-06	62.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4E8XQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
DPH1_k127_8989822_0	1094980.Mpsy_0983	3.002e-82	311.0	COG1404@1|root,arCOG02538@1|root,arCOG03439@1|root,arCOG00702@2157|Archaea,arCOG02538@2157|Archaea,arCOG03439@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Calx-beta,Inhibitor_I9,Peptidase_S8
DPH1_k127_8989822_1	195522.BD01_1926	1.21e-58	217.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,243JH@183968|Thermococci	183968|Thermococci	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DPH1_k127_8997483_4	1192034.CAP_6826	1.211e-10	68.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,43EDS@68525|delta/epsilon subdivisions,2X82V@28221|Deltaproteobacteria,2Z2G4@29|Myxococcales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DPH1_k127_8997483_0	1047013.AQSP01000059_gene2098	1.168e-137	445.0	COG0451@1|root,COG0451@2|Bacteria,2NQD6@2323|unclassified Bacteria	2|Bacteria	GM	RmlD substrate binding domain	ltd	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	Epimerase
DPH1_k127_8997483_1	351160.RRC81	6.679e-76	269.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DPH1_k127_8997483_3	1122614.JHZF01000015_gene2344	1.45e-17	97.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,2PD9R@252301|Oceanicola	28211|Alphaproteobacteria	V	Transport permease protein	yadH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DPH1_k127_8997483_2	932678.THERU_01550	6.486e-33	138.0	COG1189@1|root,COG1189@2|Bacteria,2G3MN@200783|Aquificae	200783|Aquificae	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
DPH1_k127_8997483_5	630626.EBL_c25250	0.0001353	49.0	COG1178@1|root,COG1674@1|root,COG1178@2|Bacteria,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DPH1_k127_9053681_3	1463881.KL591008_gene1935	1.507e-10	66.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
DPH1_k127_9053681_1	459349.CLOAM1622	4.436e-14	87.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM
DPH1_k127_9053681_2	102125.Xen7305DRAFT_00030960	1.61e-12	81.0	COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G2S3@1117|Cyanobacteria,3VJDP@52604|Pleurocapsales	1117|Cyanobacteria	GQ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Polysacc_deac_1
DPH1_k127_9053681_0	192952.MM_3150	3.739e-60	219.0	COG2520@1|root,arCOG10124@2157|Archaea,2XTPV@28890|Euryarchaeota,2N953@224756|Methanomicrobia	224756|Methanomicrobia	J	S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe)	taw2	-	2.5.1.114	ko:K07055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Met_10
DPH1_k127_9072805_0	1054217.TALC_00183	1.287e-39	154.0	COG1096@1|root,arCOG00676@2157|Archaea,2XYYA@28890|Euryarchaeota,241TD@183967|Thermoplasmata	183967|Thermoplasmata	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N
DPH1_k127_9072805_2	1278073.MYSTI_05718	6.688e-13	84.0	COG0823@1|root,COG3291@1|root,COG4932@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DPH1_k127_9072805_1	1183438.GKIL_1150	1.003e-21	113.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,VCBS
DPH1_k127_9175750_0	1123508.JH636439_gene345	1.314e-23	119.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_9179494_0	673860.AciM339_1559	7.858e-52	196.0	COG0522@1|root,arCOG04239@2157|Archaea,2XXYX@28890|Euryarchaeota,3F2KM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DPH1_k127_9179494_1	439481.Aboo_1396	2.764e-38	162.0	COG0099@1|root,arCOG01722@2157|Archaea,2XWHE@28890|Euryarchaeota,3F2Q4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DPH1_k127_9179494_3	998674.ATTE01000001_gene2509	1.915e-05	58.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,1RS7G@1236|Gammaproteobacteria,46256@72273|Thiotrichales	72273|Thiotrichales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DPH1_k127_9179494_2	1457250.BBMO01000001_gene1581	3.915e-24	119.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_9188268_0	368407.Memar_1743	1.265e-34	138.0	arCOG06938@1|root,arCOG06938@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9188268_1	368407.Memar_1744	1.823e-26	113.0	arCOG06937@1|root,arCOG06937@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
DPH1_k127_9188268_3	627192.SLG_17800	0.0001325	51.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2K25K@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DPH1_k127_9251927_0	192952.MM_2581	9.558e-110	366.0	COG1180@1|root,arCOG00946@2157|Archaea,2XUB7@28890|Euryarchaeota,2N915@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM Radical SAM domain protein	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
DPH1_k127_9251927_2	387631.Asulf_01764	2.761e-97	329.0	COG0150@1|root,arCOG00639@2157|Archaea,2XTBA@28890|Euryarchaeota,245YB@183980|Archaeoglobi	183980|Archaeoglobi	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DPH1_k127_9251927_3	348780.NP_4470A	5.598e-18	94.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23SVZ@183963|Halobacteria	183963|Halobacteria	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	ubiA2	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DPH1_k127_9251927_1	673860.AciM339_0552	2.682e-103	346.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,3F2GZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
DPH1_k127_9251927_6	439481.Aboo_1528	3.258e-06	58.0	arCOG03397@1|root,arCOG03397@2157|Archaea,2Y76W@28890|Euryarchaeota,3F3HH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9251927_7	15368.BRADI1G08517.1	0.0002651	49.0	COG0589@1|root,2RXWD@2759|Eukaryota,37UWB@33090|Viridiplantae,3GI2N@35493|Streptophyta,3KZ66@4447|Liliopsida,3IH6Z@38820|Poales	35493|Streptophyta	T	Universal stress protein A-like protein	-	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Usp
DPH1_k127_9251927_4	1238425.J07HQW2_02767	2.042e-17	89.0	COG1326@1|root,arCOG02680@2157|Archaea,2XUFW@28890|Euryarchaeota,23T9W@183963|Halobacteria	183963|Halobacteria	S	archaeal Zn-finger protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9251927_5	1448860.BBJO01000014_gene1327	6.036e-13	77.0	COG0746@1|root,arCOG01872@2157|Archaea,2XWJR@28890|Euryarchaeota,23V5Y@183963|Halobacteria	183963|Halobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DPH1_k127_9263258_0	497964.CfE428DRAFT_4943	1.902e-71	274.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
DPH1_k127_9267444_0	744979.R2A130_3322	2.786e-09	70.0	COG2373@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG4932@1|root,COG2373@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
DPH1_k127_9272792_0	717606.PaecuDRAFT_3496	1.609e-07	65.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1UMJD@1239|Firmicutes,4ITWR@91061|Bacilli,277F2@186822|Paenibacillaceae	91061|Bacilli	DZ	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_927886_0	439481.Aboo_1131	4.544e-227	715.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,3F2FS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TCP-1/cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
DPH1_k127_927886_1	1054217.TALC_01481	1.219e-185	596.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,241IM@183967|Thermoplasmata	183967|Thermoplasmata	O	TCP-1/cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
DPH1_k127_9284785_0	673860.AciM339_1206	2.831e-135	444.0	COG1503@1|root,arCOG01742@2157|Archaea,2XSV5@28890|Euryarchaeota,3F2IF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
DPH1_k127_9293882_2	368407.Memar_1117	3.64e-24	108.0	COG3382@1|root,arCOG04250@2157|Archaea,2Y2KD@28890|Euryarchaeota,2NAIE@224756|Methanomicrobia	224756|Methanomicrobia	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
DPH1_k127_9293882_1	1173025.GEI7407_1372	3.452e-25	111.0	COG0853@1|root,COG0853@2|Bacteria,1G6IZ@1117|Cyanobacteria,1HAUK@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
DPH1_k127_9293882_0	589924.Ferp_0541	4.399e-41	159.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DPH1_k127_9365126_0	378806.STAUR_2341	1.383e-11	76.0	COG2885@1|root,COG2931@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42T9J@68525|delta/epsilon subdivisions,2WU7T@28221|Deltaproteobacteria,2YWI9@29|Myxococcales	28221|Deltaproteobacteria	MQ	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
DPH1_k127_9365126_1	304371.MCP_2061	4.071e-05	57.0	COG0457@1|root,arCOG02497@1|root,arCOG02497@2157|Archaea,arCOG03032@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	Beta_helix,TPR_16,TPR_19
DPH1_k127_9374199_0	1410653.JHVC01000001_gene1900	1.146e-34	143.0	COG0501@1|root,COG0501@2|Bacteria,1UQUC@1239|Firmicutes,258KQ@186801|Clostridia,36RJ9@31979|Clostridiaceae	186801|Clostridia	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DPH1_k127_9374199_2	102125.Xen7305DRAFT_00030960	1.132e-22	116.0	COG1572@1|root,COG1864@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G2S3@1117|Cyanobacteria,3VJDP@52604|Pleurocapsales	1117|Cyanobacteria	GQ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Polysacc_deac_1
DPH1_k127_9374199_3	1042877.GQS_00285	1.166e-06	63.0	arCOG02499@1|root,arCOG02526@1|root,arCOG02540@1|root,arCOG02499@2157|Archaea,arCOG02526@2157|Archaea,arCOG02540@2157|Archaea,2Y66W@28890|Euryarchaeota,242VN@183968|Thermococci	183968|Thermococci	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DPH1_k127_9374199_1	439481.Aboo_0463	2.772e-29	128.0	COG0477@1|root,arCOG00130@2157|Archaea,2Y726@28890|Euryarchaeota,3F38D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K19576	-	-	-	-	ko00000,ko02000	2.A.1.2.10	-	-	MFS_1
DPH1_k127_9385543_1	387631.Asulf_00521	2.101e-13	81.0	COG3979@1|root,COG5306@1|root,arCOG02420@1|root,arCOG03511@1|root,arCOG03553@1|root,arCOG09173@1|root,arCOG02420@2157|Archaea,arCOG03508@2157|Archaea,arCOG03511@2157|Archaea,arCOG03553@2157|Archaea,arCOG07581@2157|Archaea,arCOG09173@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF2341,PKD,Pilin_N,S_layer_C
DPH1_k127_9385543_0	1121406.JAEX01000001_gene433	8.086e-43	168.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WNYM@28221|Deltaproteobacteria,2MG63@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DPH1_k127_9389521_0	78398.KS43_06410	1.547e-11	79.0	COG1853@1|root,COG2373@1|root,COG1853@2|Bacteria,COG2373@2|Bacteria,1QV7E@1224|Proteobacteria,1SM3U@1236|Gammaproteobacteria,1MSAW@122277|Pectobacterium	1236|Gammaproteobacteria	S	TIGRFAM Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3
DPH1_k127_9393724_0	1382306.JNIM01000001_gene4190	3.163e-101	343.0	COG0863@1|root,COG0863@2|Bacteria,2G650@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
DPH1_k127_9393724_1	868131.MSWAN_2066	7.532e-61	225.0	COG1408@1|root,arCOG01156@2157|Archaea,2Y1DW@28890|Euryarchaeota,23PMV@183925|Methanobacteria	183925|Methanobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DPH1_k127_9399158_1	293826.Amet_1252	7.008e-85	287.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,249UD@186801|Clostridia,36DIK@31979|Clostridiaceae	186801|Clostridia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DPH1_k127_9399158_0	880072.Desac_2889	6.779e-108	368.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	bkdF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DPH1_k127_9399158_2	304371.MCP_1721	5.747e-40	158.0	COG0095@1|root,arCOG01939@2157|Archaea,2XUJ0@28890|Euryarchaeota	28890|Euryarchaeota	H	COG0095 Lipoate-protein ligase A	lpl	GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DPH1_k127_9399158_5	448385.sce4940	3.473e-10	74.0	COG1409@1|root,COG2133@1|root,COG5563@1|root,COG1409@2|Bacteria,COG2133@2|Bacteria,COG5563@2|Bacteria,1NS3S@1224|Proteobacteria,43AFC@68525|delta/epsilon subdivisions,2X64J@28221|Deltaproteobacteria,2Z0UN@29|Myxococcales	28221|Deltaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DPH1_k127_9399158_3	926550.CLDAP_33710	8.903e-28	132.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DPH1_k127_9399158_4	1128421.JAGA01000002_gene744	1.473e-18	102.0	COG2152@1|root,COG3291@1|root,COG2152@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DPH1_k127_9448566_4	8496.XP_006257898.1	6.929e-23	115.0	KOG0613@1|root,KOG0613@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata,48Y8I@7742|Vertebrata	33208|Metazoa	T	skeletal muscle myosin thick filament assembly	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
DPH1_k127_9448566_3	290397.Adeh_3181	4.689e-25	114.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42YYA@68525|delta/epsilon subdivisions,2WTU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
DPH1_k127_9448566_1	717606.PaecuDRAFT_2033	2.344e-86	325.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_9448566_2	1297742.A176_07579	8.736e-27	130.0	COG3170@1|root,COG3170@2|Bacteria,1R2XT@1224|Proteobacteria,43DHQ@68525|delta/epsilon subdivisions,2X8PG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_9448566_0	717606.PaecuDRAFT_2033	1.904e-95	344.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_9448566_5	235985.BBPN01000033_gene35	2.923e-07	64.0	COG3291@1|root,COG3291@2|Bacteria,2HHTF@201174|Actinobacteria,2NHQJ@228398|Streptacidiphilus	201174|Actinobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Phosphoesterase,fn3
DPH1_k127_9470024_0	1094980.Mpsy_3151	3.086e-43	175.0	COG5520@1|root,arCOG03769@1|root,arCOG07561@1|root,arCOG03769@2157|Archaea,arCOG07561@2157|Archaea,arCOG09138@2157|Archaea,2XV3J@28890|Euryarchaeota,2NBAU@224756|Methanomicrobia	224756|Methanomicrobia	K	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_948722_1	673860.AciM339_0274	6.363e-34	137.0	COG2125@1|root,arCOG01946@2157|Archaea,2XXZJ@28890|Euryarchaeota,3F2RJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
DPH1_k127_948722_0	673860.AciM339_0273	1.407e-165	539.0	COG3276@1|root,arCOG01563@2157|Archaea,2XUKU@28890|Euryarchaeota,3F2I7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2g	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,eIF2_C
DPH1_k127_948722_2	1236689.MMALV_01120	1.681e-11	75.0	COG1412@1|root,arCOG04312@2157|Archaea,2Y0D4@28890|Euryarchaeota,3F2SM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	Fcf1	-	-	-	ko:K07158	-	-	-	-	ko00000	-	-	-	PIN
DPH1_k127_9503686_0	1094980.Mpsy_3151	1.798e-88	321.0	COG5520@1|root,arCOG03769@1|root,arCOG07561@1|root,arCOG03769@2157|Archaea,arCOG07561@2157|Archaea,arCOG09138@2157|Archaea,2XV3J@28890|Euryarchaeota,2NBAU@224756|Methanomicrobia	224756|Methanomicrobia	K	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9517026_0	648996.Theam_1067	3.392e-67	241.0	COG1465@1|root,COG1465@2|Bacteria,2G4EK@200783|Aquificae	200783|Aquificae	E	Belongs to the archaeal-type DHQ synthase family	-	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
DPH1_k127_9517026_1	755731.Clo1100_1902	8.046e-38	154.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,36W9X@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
DPH1_k127_9529234_0	395495.Lcho_3739	3.316e-12	77.0	COG0689@1|root,COG5276@1|root,COG0689@2|Bacteria,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria	1224|Proteobacteria	N	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,He_PIG,LVIVD
DPH1_k127_9553441_14	304371.MCP_1024	2.188e-36	148.0	COG0312@1|root,arCOG00322@2157|Archaea,2XV41@28890|Euryarchaeota,2N939@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DPH1_k127_9553441_16	196367.JNFG01000016_gene4073	1.645e-19	102.0	COG0491@1|root,COG0491@2|Bacteria,1NFZ3@1224|Proteobacteria,2WEMI@28216|Betaproteobacteria,1KHSD@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DPH1_k127_9553441_0	1191523.MROS_2233	1.226e-118	390.0	COG0205@1|root,COG0205@2|Bacteria	2|Bacteria	G	6-phosphofructokinase activity	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
DPH1_k127_9553441_21	351160.RCIX2013	2.424e-05	55.0	COG2202@1|root,arCOG03567@1|root,arCOG03567@2157|Archaea,arCOG06515@2157|Archaea,2Y7NU@28890|Euryarchaeota,2NAAT@224756|Methanomicrobia	224756|Methanomicrobia	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MEDS,PAS_3
DPH1_k127_9553441_17	304371.MCP_1545	1.253e-18	90.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DPH1_k127_9553441_15	351160.LRC18	1.234e-35	152.0	COG1404@1|root,arCOG00702@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I9,Peptidase_S8
DPH1_k127_9553441_20	1293047.CBMA010000026_gene1675	9.437e-06	57.0	COG1378@1|root,arCOG02037@2157|Archaea,2XW87@28890|Euryarchaeota,23TZW@183963|Halobacteria	183963|Halobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DPH1_k127_9553441_2	234267.Acid_5783	3.038e-96	346.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DPH1_k127_9553441_8	868131.MSWAN_0873	1.205e-54	198.0	arCOG11509@1|root,arCOG11509@2157|Archaea,2Y3KG@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9553441_9	335543.Sfum_0395	9.08e-49	180.0	COG3945@1|root,COG3945@2|Bacteria,1N3AR@1224|Proteobacteria,42UWM@68525|delta/epsilon subdivisions,2WQEC@28221|Deltaproteobacteria,2MQIV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
DPH1_k127_9553441_6	573063.Metin_1020	1.213e-61	220.0	COG0108@1|root,arCOG01320@2157|Archaea,2XTDZ@28890|Euryarchaeota,23Q9J@183939|Methanococci	183939|Methanococci	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
DPH1_k127_9553441_13	673860.AciM339_0317	6.909e-37	156.0	COG0615@1|root,arCOG01222@2157|Archaea,2XX70@28890|Euryarchaeota,3F2RF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme	ribL	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.7.2	ko:K14656	ko00740,ko01100,ko01110,map00740,map01100,map01110	-	R00161	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DPH1_k127_9553441_5	439481.Aboo_0746	2.336e-63	230.0	COG1731@1|root,arCOG01322@2157|Archaea,2XX0K@28890|Euryarchaeota,3F2K2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	6,7-dimethyl-8-ribityllumazine synthase	ribC	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DPH1_k127_9553441_10	439481.Aboo_0745	3.8e-48	176.0	COG0054@1|root,arCOG01323@2157|Archaea,2XXXC@28890|Euryarchaeota,3F2P5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DPH1_k127_9553441_12	1304885.AUEY01000001_gene3149	3.389e-45	175.0	28JZ9@1|root,2Z9PC@2|Bacteria,1R7GE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9553441_22	1183438.GKIL_1089	0.0005938	52.0	COG0463@1|root,COG3420@1|root,COG0463@2|Bacteria,COG3420@2|Bacteria,1GHC6@1117|Cyanobacteria	1117|Cyanobacteria	P	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_9553441_3	1125863.JAFN01000001_gene2513	2.194e-87	310.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
DPH1_k127_9553441_7	1499967.BAYZ01000009_gene5246	5.981e-58	212.0	COG0778@1|root,COG0778@2|Bacteria,2NQZY@2323|unclassified Bacteria	2|Bacteria	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DPH1_k127_9553441_11	1379698.RBG1_1C00001G1377	2.449e-46	188.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
DPH1_k127_9553441_23	351160.RCIX1061	0.0005941	48.0	arCOG01210@1|root,arCOG01210@2157|Archaea	2157|Archaea	S	DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9553441_1	439481.Aboo_1224	5.235e-117	392.0	COG0252@1|root,arCOG01924@2157|Archaea,2XTN1@28890|Euryarchaeota,3F2GG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DPH1_k127_9553441_4	1236689.MMALV_16300	1.724e-85	292.0	COG2511@1|root,arCOG01719@2157|Archaea,2XT73@28890|Euryarchaeota,3F2IW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
DPH1_k127_9559268_0	717606.PaecuDRAFT_2033	8.947e-70	261.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_9565458_0	1041930.Mtc_0628	8.909e-128	419.0	COG1089@1|root,arCOG01373@2157|Archaea,2XUVY@28890|Euryarchaeota,2N9AM@224756|Methanomicrobia	224756|Methanomicrobia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DPH1_k127_9565458_3	300852.55771415	4.836e-05	53.0	COG1848@1|root,COG1848@2|Bacteria,1WK2Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
DPH1_k127_9565458_1	1457250.BBMO01000001_gene1581	9.97e-102	372.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
DPH1_k127_9565458_2	754477.Q7C_1866	1.59e-76	292.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,4608F@72273|Thiotrichales	72273|Thiotrichales	U	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
DPH1_k127_9574413_0	673860.AciM339_0069	1.064e-67	244.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUW2@28890|Euryarchaeota,3F2R0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Mechanosensitive ion channel	-	-	-	ko:K03442,ko:K05802,ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.2,1.A.23.4	-	-	MS_channel
DPH1_k127_9651485_1	443906.CMM_0825	2.439e-21	111.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DPH1_k127_9651485_2	81824.XP_001749093.1	1.147e-10	76.0	29QRV@1|root,2RX97@2759|Eukaryota,38CMN@33154|Opisthokonta	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DPH1_k127_9651485_0	204669.Acid345_0471	8.137e-28	125.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9680843_0	671143.DAMO_0892	2.65e-135	436.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.38	ko:K01371	ko04142,ko04210,ko04380,ko04620,ko05323,map04142,map04210,map04380,map04620,map05323	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_C1
DPH1_k127_9680843_3	1506583.JQJY01000001_gene324	2.858e-26	122.0	COG4932@1|root,COG4932@2|Bacteria,4NT1H@976|Bacteroidetes,1I663@117743|Flavobacteriia,2NV9S@237|Flavobacterium	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9680843_2	529709.PYCH_10030	3.328e-47	178.0	COG1756@1|root,arCOG04122@2157|Archaea,2XX9G@28890|Euryarchaeota,243H9@183968|Thermococci	183968|Thermococci	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
DPH1_k127_9680843_1	1304885.AUEY01000082_gene2157	2.463e-58	209.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42MSW@68525|delta/epsilon subdivisions,2WNY3@28221|Deltaproteobacteria,2MJ39@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DPH1_k127_9693656_1	251221.35214774	1.887e-67	262.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
DPH1_k127_9693656_2	649831.L083_3335	1.269e-55	224.0	COG4733@1|root,COG4733@2|Bacteria,2I61V@201174|Actinobacteria,4DJUW@85008|Micromonosporales	201174|Actinobacteria	MU	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DPH1_k127_9693656_0	717606.PaecuDRAFT_2033	3.59e-92	344.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_9693656_4	1536770.R50345_20080	7.899e-16	93.0	COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase family 6	guxA	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
DPH1_k127_9693656_3	1297742.A176_02953	4.296e-46	193.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DPH1_k127_9711725_2	224325.AF_0575	7.493e-34	142.0	COG0491@1|root,arCOG00504@2157|Archaea,2XURS@28890|Euryarchaeota,2467X@183980|Archaeoglobi	183980|Archaeoglobi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DPH1_k127_9711725_1	1304284.L21TH_1612	1.214e-123	413.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,36DFC@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	tnaT	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
DPH1_k127_9711725_0	1041930.Mtc_0639	4.37e-141	453.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,2N980@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
DPH1_k127_9711725_3	1227484.C471_01449	1.415e-29	123.0	COG0675@1|root,arCOG00679@2157|Archaea,2Y8F9@28890|Euryarchaeota,241A7@183963|Halobacteria	183963|Halobacteria	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
DPH1_k127_9728184_0	70601.3258073	2.408e-71	254.0	COG0130@1|root,arCOG00987@2157|Archaea,2XTUE@28890|Euryarchaeota,243K5@183968|Thermococci	183968|Thermococci	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481	-	ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
DPH1_k127_9728184_2	1094980.Mpsy_1120	3.521e-40	156.0	COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,2N9PR@224756|Methanomicrobia	224756|Methanomicrobia	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DPH1_k127_9728184_3	439481.Aboo_1496	3.974e-22	105.0	COG1422@1|root,arCOG02673@2157|Archaea,2XZDK@28890|Euryarchaeota,3F2U5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Integral membrane protein DUF106	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
DPH1_k127_9728184_1	573063.Metin_0612	4.447e-53	193.0	COG2019@1|root,arCOG01039@2157|Archaea,2XVK7@28890|Euryarchaeota,23Q7F@183939|Methanococci	183939|Methanococci	F	ATP-AMP transphosphorylase	adkA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
DPH1_k127_9807830_1	192952.MM_1297	2.493e-05	50.0	COG0430@1|root,arCOG04125@2157|Archaea,2XT7I@28890|Euryarchaeota,2N9B3@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
DPH1_k127_9807830_0	742818.HMPREF9451_01064	4.759e-30	130.0	COG0652@1|root,COG0652@2|Bacteria,2HUQ0@201174|Actinobacteria,4CVCH@84998|Coriobacteriia	84998|Coriobacteriia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DPH1_k127_9826514_4	523850.TON_1189	1.275e-16	88.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota,242UN@183968|Thermococci	183968|Thermococci	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB1	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_9826514_3	439481.Aboo_0143	4.813e-20	103.0	COG3351@1|root,arCOG02964@2157|Archaea,2XVP0@28890|Euryarchaeota,3F2YQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Flagella accessory protein C (FlaC)	flaD	-	-	ko:K07327,ko:K07328	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_fla_DE,FlaC_arch
DPH1_k127_9826514_6	413816.BBJP01000030_gene1945	2.067e-06	55.0	COG3353@1|root,arCOG01824@2157|Archaea	2157|Archaea	N	Archaeal flagellar protein F	flaF	-	-	ko:K07329	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_9826514_5	439481.Aboo_1320	5.943e-11	69.0	COG3354@1|root,arCOG01822@2157|Archaea,2Y176@28890|Euryarchaeota,3F3BF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Archaebacterial flagellin	-	-	-	ko:K07330	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DPH1_k127_9826514_2	1094980.Mpsy_2349	1.455e-61	220.0	COG2874@1|root,arCOG04148@2157|Archaea,2XUMD@28890|Euryarchaeota,2N9IB@224756|Methanomicrobia	224756|Methanomicrobia	N	KaiC	-	-	-	ko:K07331	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ATPase
DPH1_k127_9826514_0	573063.Metin_1102	5.327e-184	591.0	COG4962@1|root,arCOG01817@2157|Archaea,2XTDM@28890|Euryarchaeota,23Q0D@183939|Methanococci	183939|Methanococci	N	PFAM Type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DPH1_k127_9826514_1	439481.Aboo_1317	6.383e-91	321.0	COG1955@1|root,arCOG01809@2157|Archaea,2XTAX@28890|Euryarchaeota,3F2ZF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	flaJ	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DPH1_k127_9841306_1	1173028.ANKO01000216_gene6188	2.242e-15	91.0	COG0689@1|root,COG2931@1|root,COG5184@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Calx-beta,Chlam_PMP,DUF4347,HemolysinCabind
DPH1_k127_9841306_2	880073.Calab_2183	3.042e-12	81.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Calx-beta,DUF5122,Haemagg_act,HemolysinCabind,PPC,VCBS
DPH1_k127_9841306_0	717606.PaecuDRAFT_3496	4.432e-16	93.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1UMJD@1239|Firmicutes,4ITWR@91061|Bacilli,277F2@186822|Paenibacillaceae	91061|Bacilli	DZ	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DPH1_k127_9872050_0	1382306.JNIM01000001_gene441	3.028e-96	326.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DPH1_k127_9872050_1	269799.Gmet_1576	2.161e-93	324.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,42NBN@68525|delta/epsilon subdivisions,2WK8A@28221|Deltaproteobacteria,43U0B@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DPH1_k127_9872050_3	525904.Tter_1673	5.86e-56	199.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
DPH1_k127_9872050_2	479434.Sthe_1202	1.792e-72	246.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DPH1_k127_9900720_0	717606.PaecuDRAFT_2033	6.811e-90	334.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DPH1_k127_9900720_1	1386089.N865_05350	4.65e-47	196.0	COG4733@1|root,COG4733@2|Bacteria,2I7XV@201174|Actinobacteria,4FK2V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DPH1_k127_9904063_0	1236689.MMALV_02980	1.503e-92	310.0	COG0689@1|root,arCOG01575@2157|Archaea,2XVHI@28890|Euryarchaeota,3F2GE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DPH1_k127_9904063_1	673860.AciM339_0867	4.736e-67	244.0	COG1097@1|root,arCOG00678@2157|Archaea,2XWEN@28890|Euryarchaeota,3F2JY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,KH_1,KH_6,S1
DPH1_k127_9956065_1	909663.KI867150_gene2309	1.671e-06	55.0	COG4447@1|root,COG4447@2|Bacteria,1PFB5@1224|Proteobacteria,437G8@68525|delta/epsilon subdivisions,2X2NT@28221|Deltaproteobacteria,2MRPS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DPH1_k127_9956065_0	1236689.MMALV_03240	1.423e-69	237.0	COG0048@1|root,arCOG04255@2157|Archaea,2XX4A@28890|Euryarchaeota,3F2K0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DPH1_k127_9984684_2	1565129.JSFF01000014_gene434	4.286e-05	59.0	COG1361@1|root,COG1361@2|Bacteria,1R6R8@1224|Proteobacteria,1RZFS@1236|Gammaproteobacteria,2Q9ZJ@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
DPH1_k127_9984684_1	324602.Caur_0392	6.512e-32	147.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,2GA7Y@200795|Chloroflexi,376PQ@32061|Chloroflexia	32061|Chloroflexia	M	SMART Parallel beta-helix repeat	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NPCBM_assoc
DPH1_k127_9984684_0	673860.AciM339_0256	3.96e-173	578.0	COG1793@1|root,arCOG01347@2157|Archaea,2XTCK@28890|Euryarchaeota,3F2GX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
DPH1_k127_998569_4	1112216.JH594425_gene1244	1.225e-08	70.0	COG2911@1|root,COG2931@1|root,COG2982@1|root,COG3637@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3637@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K0IP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,He_PIG,HemolysinCabind
DPH1_k127_998569_3	471854.Dfer_3148	1.611e-21	113.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
DPH1_k127_998569_1	439481.Aboo_0635	2.846e-82	288.0	COG0112@1|root,arCOG00070@2157|Archaea,2XX80@28890|Euryarchaeota,3F334@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Serine hydroxymethyltransferase	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DPH1_k127_998569_5	1042877.GQS_07885	5.759e-08	63.0	COG1895@1|root,arCOG02123@2157|Archaea,2Y05T@28890|Euryarchaeota,244GD@183968|Thermococci	183968|Thermococci	S	HEPN domain	-	-	-	ko:K09132	-	-	-	-	ko00000	-	-	-	HEPN
DPH1_k127_998569_2	518766.Rmar_2866	8.835e-22	102.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
DPH1_k127_998569_0	1041930.Mtc_2490	1.168e-190	620.0	COG1204@1|root,arCOG00553@2157|Archaea,2XSV4@28890|Euryarchaeota,2N9A8@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
## 1924 queries scanned
## Total time (seconds): 7.107996940612793
## Rate: 270.68 q/s