## Mon Feb 16 12:05:34 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/DTH1_bin.5.fa -m mmseqs --output DTH1_bin.5 --output_dir /data/result/bins/wyx/eggqs50+/DTH1_bin.5 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DTH1_k127_10005658_4	323850.Shew_1118	0.0002544	44.0	COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria,1S1E0@1236|Gammaproteobacteria,2Q8JZ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
DTH1_k127_10005658_1	1210884.HG799472_gene14911	2.628e-115	384.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_10005658_2	1396418.BATQ01000058_gene110	4.757e-21	95.0	2EMGZ@1|root,33F5K@2|Bacteria,46TB4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_10005658_3	357808.RoseRS_4349	1.515e-13	78.0	COG1247@1|root,COG1247@2|Bacteria,2G9YI@200795|Chloroflexi,377A3@32061|Chloroflexia	32061|Chloroflexia	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_10005658_0	497964.CfE428DRAFT_1508	6.781e-169	538.0	COG1620@1|root,COG1620@2|Bacteria,46UQW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	L-lactate permease	-	-	-	-	-	-	-	-	-	-	-	-	Lactate_perm
DTH1_k127_1003307_3	497964.CfE428DRAFT_3580	5.796e-27	112.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_1003307_0	497964.CfE428DRAFT_3579	2.664e-234	750.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_1003307_1	1123070.KB899248_gene60	3.941e-214	674.0	COG0017@1|root,COG0017@2|Bacteria,46TN6@74201|Verrucomicrobia,2ITHF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH1_k127_1003307_2	243231.GSU3381	2.313e-154	518.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,43TFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH1_k127_10059478_0	1121904.ARBP01000042_gene4905	2.697e-115	400.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH1_k127_10059478_3	1396141.BATP01000060_gene4559	0.0004003	48.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
DTH1_k127_10059478_1	452637.Oter_4097	5.871e-112	374.0	COG0385@1|root,COG0385@2|Bacteria,46YMH@74201|Verrucomicrobia,3K9UA@414999|Opitutae	414999|Opitutae	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
DTH1_k127_10059478_2	497964.CfE428DRAFT_4161	1.232e-68	241.0	COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
DTH1_k127_10074736_0	1123242.JH636434_gene3333	7.416e-95	319.0	COG4692@1|root,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_10074736_2	575540.Isop_1614	2.365e-55	220.0	COG2373@1|root,COG2373@2|Bacteria,2IZBV@203682|Planctomycetes	203682|Planctomycetes	Q	aggregation factor core protein MAFp3, isoform C	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
DTH1_k127_10074736_1	1192034.CAP_0893	9.136e-59	230.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
DTH1_k127_10074736_3	1121405.dsmv_0737	5.421e-10	71.0	COG1649@1|root,COG2133@1|root,COG2755@1|root,COG3023@1|root,COG3250@1|root,COG3291@1|root,COG1649@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3023@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,1R2HQ@1224|Proteobacteria,42ZN7@68525|delta/epsilon subdivisions,2WUV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
DTH1_k127_1010556_3	382464.ABSI01000011_gene2813	1.711e-11	66.0	COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
DTH1_k127_1010556_1	243090.RB11088	3.629e-199	637.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DTH1_k127_1010556_0	452637.Oter_2956	9.294e-227	713.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
DTH1_k127_1010556_2	452637.Oter_2957	7.936e-118	388.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
DTH1_k127_10106593_0	1396418.BATQ01000175_gene2745	1.51e-75	260.0	COG1387@1|root,COG1387@2|Bacteria,46SMB@74201|Verrucomicrobia,2IU6X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
DTH1_k127_10106593_2	1125863.JAFN01000001_gene1790	6.526e-43	163.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH1_k127_10106593_1	452637.Oter_2449	1.807e-66	233.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K7Y9@414999|Opitutae	414999|Opitutae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH1_k127_10106593_5	1453505.JASY01000013_gene4343	0.0004876	49.0	2CIT3@1|root,32Y0C@2|Bacteria,4NUWR@976|Bacteroidetes,1I533@117743|Flavobacteriia,2NWGN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
DTH1_k127_1019494_4	1158338.JNLJ01000001_gene244	1.025e-11	65.0	COG1127@1|root,COG1127@2|Bacteria,2G3XY@200783|Aquificae	200783|Aquificae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH1_k127_1019494_3	1123371.ATXH01000005_gene2035	2.283e-35	147.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH1_k127_1019494_0	709986.Deima_0518	2.155e-156	513.0	COG1092@1|root,COG1092@2|Bacteria,1WK2R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH1_k127_1019494_1	1254432.SCE1572_02560	5.216e-139	456.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH1_k127_1019494_5	1096930.L284_00460	4.083e-05	55.0	COG5349@1|root,COG5349@2|Bacteria,1N0PN@1224|Proteobacteria,2UBSH@28211|Alphaproteobacteria,2K5S3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
DTH1_k127_1019494_2	1267534.KB906755_gene4489	3.631e-87	301.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH1_k127_1019494_6	595460.RRSWK_00638	0.0001056	46.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2IWZA@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,ABC_tran
DTH1_k127_1025513_0	1396141.BATP01000003_gene4934	8.856e-104	373.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
DTH1_k127_1036613_2	1123508.JH636439_gene1468	8.739e-23	112.0	COG0515@1|root,COG3642@1|root,COG0515@2|Bacteria,COG3642@2|Bacteria,2IZTN@203682|Planctomycetes	203682|Planctomycetes	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
DTH1_k127_1036613_1	237368.SCABRO_03057	4.199e-77	274.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
DTH1_k127_1036613_0	204669.Acid345_0011	5.208e-158	512.0	COG5316@1|root,COG5316@2|Bacteria,3Y4FP@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
DTH1_k127_1049238_2	1385935.N836_19490	7.953e-22	108.0	COG3464@1|root,COG3464@2|Bacteria,1G9CU@1117|Cyanobacteria,1HGU0@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1049238_0	886293.Sinac_3103	1.723e-83	287.0	COG1082@1|root,COG1082@2|Bacteria,2IZ3D@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_1049238_1	1396418.BATQ01000175_gene2763	1.526e-47	173.0	COG3119@1|root,COG3119@2|Bacteria,46V0M@74201|Verrucomicrobia,2IU1S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
DTH1_k127_1058668_1	42256.RradSPS_2550	3.025e-20	96.0	COG0212@1|root,COG0212@2|Bacteria	2|Bacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
DTH1_k127_1058668_2	344747.PM8797T_00964	1.198e-07	62.0	2FF0U@1|root,346Z8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1058668_0	497964.CfE428DRAFT_0415	3.809e-175	560.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DTH1_k127_1077088_2	84531.JMTZ01000052_gene1595	3.616e-92	308.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1X3YD@135614|Xanthomonadales	135614|Xanthomonadales	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DTH1_k127_1077088_3	1123073.KB899243_gene738	3.292e-60	217.0	COG1392@1|root,COG1392@2|Bacteria,1PKQF@1224|Proteobacteria,1SMFE@1236|Gammaproteobacteria,1X412@135614|Xanthomonadales	135614|Xanthomonadales	P	Pit accessory protein	VL23_21310	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DTH1_k127_1077088_1	1123242.JH636435_gene3064	7.889e-108	365.0	COG0477@1|root,COG0477@2|Bacteria,2IX7U@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
DTH1_k127_1077088_0	497964.CfE428DRAFT_0621	7.392e-117	387.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH1_k127_1077088_5	443598.AUFA01000004_gene5330	0.0004591	45.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,3JW83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
DTH1_k127_1077088_4	1267535.KB906767_gene1409	8.375e-09	62.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria,2JHNA@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
DTH1_k127_1086995_0	521674.Plim_3779	6.94e-111	374.0	COG2755@1|root,COG2755@2|Bacteria,2IZBK@203682|Planctomycetes	203682|Planctomycetes	E	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase
DTH1_k127_1086995_1	204669.Acid345_4052	1.589e-84	293.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
DTH1_k127_1093217_1	926550.CLDAP_39920	1.786e-08	68.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
DTH1_k127_1093217_0	696747.NIES39_O02270	3.252e-29	137.0	COG2931@1|root,COG4675@1|root,COG2931@2|Bacteria,COG4675@2|Bacteria,1GFPS@1117|Cyanobacteria,1HHVN@1150|Oscillatoriales	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH1_k127_1124667_2	1303518.CCALI_00133	2.848e-18	100.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	galA	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_4_9,CBM_6,DUF1565
DTH1_k127_1124667_1	118173.KB235914_gene3829	2.623e-138	463.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1124667_0	497964.CfE428DRAFT_3698	5.66e-141	467.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
DTH1_k127_113077_4	1227497.C491_00797	1.028e-16	79.0	COG2311@1|root,arCOG06418@2157|Archaea,2XUST@28890|Euryarchaeota,23U4C@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
DTH1_k127_113077_2	1439940.BAY1663_01913	9.5e-99	336.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
DTH1_k127_113077_0	240016.ABIZ01000001_gene5721	7.837e-255	817.0	COG0577@1|root,COG0577@2|Bacteria,46S5D@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_113077_1	452637.Oter_2206	4.581e-108	356.0	COG1136@1|root,COG1136@2|Bacteria,46SAX@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_113077_3	794903.OPIT5_24500	1.457e-19	90.0	COG0657@1|root,COG0657@2|Bacteria,46VDF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
DTH1_k127_1147294_2	886293.Sinac_6489	5.715e-114	388.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
DTH1_k127_1147294_3	497964.CfE428DRAFT_4864	1.035e-62	224.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1147294_1	1226325.HMPREF1548_02230	1.126e-137	464.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
DTH1_k127_1147294_0	760568.Desku_2930	1.952e-169	546.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,260H6@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DTH1_k127_1173321_0	497964.CfE428DRAFT_0259	8.043e-59	209.0	COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH1_k127_1173321_1	278957.ABEA03000019_gene1865	4.364e-32	133.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
DTH1_k127_1173321_2	404380.Gbem_3451	5.942e-23	103.0	COG1215@1|root,COG1215@2|Bacteria,1NFA4@1224|Proteobacteria,42WEV@68525|delta/epsilon subdivisions,2WS1J@28221|Deltaproteobacteria,43U0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
DTH1_k127_1175184_3	497964.CfE428DRAFT_6471	9.669e-30	119.0	COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH1_k127_1175184_0	521674.Plim_2636	2.141e-140	463.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
DTH1_k127_1175184_1	1111479.AXAR01000001_gene213	8.371e-61	222.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,278V8@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH1_k127_1175184_2	497964.CfE428DRAFT_4874	3.612e-32	131.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343,Lipase_GDSL,Lipase_GDSL_2
DTH1_k127_1189851_0	1396418.BATQ01000135_gene3650	4.514e-31	134.0	COG2165@1|root,COG2165@2|Bacteria,46W6U@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH1_k127_1196108_0	56780.SYN_03067	1.381e-36	149.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SmpA_OmlA,SusD-like_3
DTH1_k127_1196108_1	5145.XP_001903535.1	2.737e-28	128.0	KOG0272@1|root,KOG0272@2759|Eukaryota,3AFR9@33154|Opisthokonta,3Q43U@4751|Fungi,3RM91@4890|Ascomycota,21RI5@147550|Sordariomycetes	4751|Fungi	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,NACHT_N,WD40
DTH1_k127_1204654_3	880073.Calab_3717	4.408e-18	87.0	COG1232@1|root,COG1232@2|Bacteria,2NQ1W@2323|unclassified Bacteria	2|Bacteria	H	Flavin containing amine oxidoreductase	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
DTH1_k127_1204654_4	391625.PPSIR1_12288	1.195e-07	60.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
DTH1_k127_1204654_0	583355.Caka_2769	1.418e-159	515.0	COG0635@1|root,COG0635@2|Bacteria,46TQX@74201|Verrucomicrobia,3K7DD@414999|Opitutae	414999|Opitutae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH1_k127_1204654_1	382464.ABSI01000010_gene3644	7.281e-117	388.0	COG0407@1|root,COG0407@2|Bacteria,46X9N@74201|Verrucomicrobia,2IV4H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_1204654_2	452637.Oter_0906	6.472e-47	179.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH1_k127_1225923_0	497964.CfE428DRAFT_2154	7.734e-185	600.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH1_k127_1225923_2	926566.Terro_3682	3.094e-51	190.0	COG2152@1|root,COG2152@2|Bacteria,3Y5H3@57723|Acidobacteria,2JM4K@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_1225923_4	452637.Oter_1440	3.565e-08	57.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
DTH1_k127_1225923_3	1125863.JAFN01000001_gene83	4.272e-50	186.0	COG2020@1|root,COG2020@2|Bacteria,1RBUU@1224|Proteobacteria,42UT0@68525|delta/epsilon subdivisions,2WQKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DTH1_k127_1225923_1	926569.ANT_25430	1.501e-93	323.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
DTH1_k127_124464_1	595460.RRSWK_04460	4.02e-48	184.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH1_k127_124464_0	1123242.JH636436_gene23	1.562e-85	304.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_1255836_2	1403819.BATR01000057_gene1772	4.468e-51	188.0	COG3474@1|root,COG3474@2|Bacteria,46TEP@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_1255836_8	497964.CfE428DRAFT_6108	0.0005239	52.0	2FCZ3@1|root,3451R@2|Bacteria,46WBW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH1_k127_1255836_7	1124982.MSI_15100	2.094e-06	58.0	COG2834@1|root,COG2834@2|Bacteria,2J5AT@203691|Spirochaetes	203691|Spirochaetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
DTH1_k127_1255836_0	309799.DICTH_1451	1.362e-263	834.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DTH1_k127_1255836_4	515635.Dtur_1559	2.792e-17	87.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH1_k127_1255836_3	589865.DaAHT2_0883	6.02e-18	90.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2MMDF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH1_k127_1255836_1	1267535.KB906767_gene952	2.214e-155	505.0	COG0673@1|root,COG0673@2|Bacteria,3Y65Y@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_1255836_5	243090.RB7746	3.363e-11	68.0	COG3119@1|root,COG3119@2|Bacteria,2J2HN@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_1255836_6	1142394.PSMK_09720	4.005e-11	75.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_125887_3	1082933.MEA186_06837	9.573e-35	136.0	COG4122@1|root,COG4122@2|Bacteria,1NR4H@1224|Proteobacteria	1224|Proteobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_125887_4	690850.Desaf_2652	4.068e-26	122.0	COG0438@1|root,COG0438@2|Bacteria,1R9QG@1224|Proteobacteria,42PQQ@68525|delta/epsilon subdivisions,2WTQJ@28221|Deltaproteobacteria,2M9KJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH1_k127_125887_10	491915.Aflv_2575	0.0001404	53.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HCKY@91061|Bacilli,21WRB@150247|Anoxybacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_16,TPR_8
DTH1_k127_125887_9	1246445.ANAY01000001_gene403	3.581e-05	56.0	COG0438@1|root,COG0438@2|Bacteria,2GNUU@201174|Actinobacteria,4EI9I@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH1_k127_125887_1	521011.Mpal_2181	1.055e-38	154.0	COG0500@1|root,arCOG01789@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH1_k127_125887_5	926554.KI912668_gene5115	1.299e-20	103.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH1_k127_125887_6	1396141.BATP01000035_gene4053	2.351e-17	96.0	29ZA9@1|root,30M8M@2|Bacteria,46XI8@74201|Verrucomicrobia,2IVZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_125887_2	497964.CfE428DRAFT_0276	3.098e-37	145.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH1_k127_125887_0	935567.JAES01000014_gene1558	1.555e-102	350.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
DTH1_k127_125887_8	278957.ABEA03000185_gene1564	4.255e-08	55.0	COG1613@1|root,COG1613@2|Bacteria,46S73@74201|Verrucomicrobia,3K7QE@414999|Opitutae	414999|Opitutae	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
DTH1_k127_125947_8	589865.DaAHT2_0558	2.285e-23	102.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2MIBY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
DTH1_k127_125947_1	497964.CfE428DRAFT_6291	2.707e-169	544.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
DTH1_k127_125947_7	497964.CfE428DRAFT_2488	4.808e-79	285.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_125947_5	497964.CfE428DRAFT_2489	6.721e-83	283.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
DTH1_k127_125947_2	497964.CfE428DRAFT_2490	5.667e-158	519.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
DTH1_k127_125947_3	1123242.JH636434_gene3280	7.698e-158	511.0	COG0823@1|root,COG0823@2|Bacteria,2IYQ1@203682|Planctomycetes	203682|Planctomycetes	U	Protein of unknown function (DUF3748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
DTH1_k127_125947_6	269799.Gmet_2367	1.585e-79	287.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH1_k127_125947_4	1211777.BN77_p2190020	5.677e-117	387.0	COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,2TTTJ@28211|Alphaproteobacteria,4BCIX@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	NAD(P)H-binding	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH1_k127_125947_0	240016.ABIZ01000001_gene2819	1.766e-183	591.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
DTH1_k127_1271998_1	926569.ANT_13690	7.311e-55	196.0	COG2407@1|root,COG2407@2|Bacteria,2G84V@200795|Chloroflexi	200795|Chloroflexi	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
DTH1_k127_1271998_0	237368.SCABRO_00906	3.537e-110	377.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH1_k127_1271998_2	269799.Gmet_2529	2.088e-42	164.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WNZ3@28221|Deltaproteobacteria,43SW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH1_k127_1287811_1	622637.KE124774_gene1017	3.102e-75	260.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria,2U18H@28211|Alphaproteobacteria,36Z9T@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DTH1_k127_1287811_2	632518.Calow_0752	4.229e-24	103.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
DTH1_k127_1287811_4	289376.THEYE_A0819	3.69e-17	83.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
DTH1_k127_1287811_0	1382315.JPOI01000001_gene3005	4.162e-87	293.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1WE2C@129337|Geobacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DTH1_k127_1287811_3	497964.CfE428DRAFT_0567	3.444e-22	97.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DTH1_k127_1306515_11	1185876.BN8_03583	6.058e-06	51.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,47NRI@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
DTH1_k127_1306515_5	525904.Tter_2139	7.8e-67	239.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH1_k127_1306515_1	525904.Tter_2133	1.325e-128	421.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
DTH1_k127_1306515_8	1163409.UUA_06087	1.132e-21	106.0	COG0697@1|root,COG0697@2|Bacteria,1PXBY@1224|Proteobacteria,1TCXJ@1236|Gammaproteobacteria,1X9UW@135614|Xanthomonadales	135614|Xanthomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH1_k127_1306515_10	1457250.BBMO01000003_gene3175	1.639e-11	72.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0NY@28890|Euryarchaeota,23Y3K@183963|Halobacteria	183963|Halobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_1306515_7	66874.JOFS01000006_gene4504	6.977e-44	186.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
DTH1_k127_1306515_4	502025.Hoch_1100	2.159e-80	305.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
DTH1_k127_1306515_0	1047013.AQSP01000089_gene1181	2.411e-139	468.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
DTH1_k127_1306515_2	1210884.HG799469_gene14163	1.673e-121	406.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_1306515_9	1303518.CCALI_01258	1.107e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_1306515_3	1396141.BATP01000056_gene3118	1.197e-117	400.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,2IWN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
DTH1_k127_1306515_6	382464.ABSI01000010_gene3853	2.293e-62	225.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DTH1_k127_1306515_12	452637.Oter_1848	0.000958	45.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH1_k127_1306515_13	452637.Oter_1848	0.0009726	42.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH1_k127_1308951_2	234267.Acid_2801	7.228e-107	350.0	COG3386@1|root,COG3386@2|Bacteria,3Y5XH@57723|Acidobacteria	2|Bacteria	G	SMP-30/Gluconolaconase/LRE-like region	MA20_02675	-	3.1.1.17	ko:K01053,ko:K13735	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05100,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220,map05100	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	NHL,SGL
DTH1_k127_1308951_0	1396141.BATP01000033_gene4259	3.952e-171	560.0	COG1200@1|root,COG1200@2|Bacteria,46TTC@74201|Verrucomicrobia,2ITXG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RecG wedge domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DTH1_k127_1308951_1	886293.Sinac_4612	3.122e-111	365.0	2BZ6M@1|root,2Z7HW@2|Bacteria,2IXV4@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_1320693_4	269799.Gmet_2345	2.351e-11	68.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH1_k127_1320693_3	497964.CfE428DRAFT_3455	1.693e-40	165.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
DTH1_k127_1320693_1	1156937.MFUM_690053	1.168e-118	392.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,37G5N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
DTH1_k127_1320693_0	344747.PM8797T_07534	9.909e-174	557.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1320693_2	452637.Oter_2739	9.307e-66	237.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,3K7I6@414999|Opitutae	414999|Opitutae	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
DTH1_k127_1320783_0	497964.CfE428DRAFT_1043	6.081e-127	415.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DTH1_k127_1320783_1	1396141.BATP01000023_gene577	1.637e-27	122.0	COG0132@1|root,COG0132@2|Bacteria,46VJB@74201|Verrucomicrobia,2IUDQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
DTH1_k127_1320783_2	670487.Ocepr_1062	1.294e-19	91.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,1WN2N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
DTH1_k127_1325343_2	344747.PM8797T_11389	5.426e-121	395.0	COG1172@1|root,COG1172@2|Bacteria,2IZWQ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K10559,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
DTH1_k127_1325343_0	344747.PM8797T_11384	6.426e-189	601.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	2|Bacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA_3	-	3.6.3.17	ko:K10441,ko:K17210	ko02010,map02010	M00212,M00592	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21	-	-	ABC_tran
DTH1_k127_1325343_1	344747.PM8797T_11379	3.309e-130	424.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
DTH1_k127_1325343_3	797209.ZOD2009_14571	5.173e-69	256.0	COG1621@1|root,arCOG08134@2157|Archaea,2XUXA@28890|Euryarchaeota,23UA6@183963|Halobacteria	183963|Halobacteria	G	COG1621 Beta-fructosidases (levanase invertase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
DTH1_k127_1331780_0	886293.Sinac_7494	2.626e-157	499.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_1331780_2	1235803.C825_05233	4.373e-33	149.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes,2FY0D@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1331780_1	639030.JHVA01000001_gene3738	5.836e-89	302.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
DTH1_k127_1332314_3	1122176.KB903531_gene3073	1.85e-11	76.0	COG2312@1|root,COG2312@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
DTH1_k127_1332314_2	497964.CfE428DRAFT_4549	5.058e-65	230.0	COG0800@1|root,COG0800@2|Bacteria,46VG5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
DTH1_k127_1332314_0	1396418.BATQ01000185_gene2103	1.757e-219	711.0	COG1572@1|root,COG2010@1|root,COG2133@1|root,COG1572@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH1_k127_1332314_1	1396141.BATP01000021_gene161	9.108e-120	392.0	COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,2ITX7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
DTH1_k127_1335350_1	1210884.HG799466_gene12644	1.112e-39	152.0	COG1680@1|root,COG1680@2|Bacteria,2IX14@203682|Planctomycetes	203682|Planctomycetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH1_k127_1335350_0	247490.KSU1_C1712	3.014e-130	436.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1335350_2	1380391.JIAS01000005_gene2424	4.679e-18	98.0	28Q55@1|root,2ZCN6@2|Bacteria,1P7CW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1342125_2	1122971.BAME01000022_gene2388	1.472e-08	59.0	COG1520@1|root,COG4225@1|root,COG1520@2|Bacteria,COG4225@2|Bacteria,4NM00@976|Bacteroidetes,2FR1A@200643|Bacteroidia,22X4Z@171551|Porphyromonadaceae	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,Glyco_hydro_88,PQQ_2
DTH1_k127_1342125_0	509191.AEDB02000002_gene1137	1.837e-105	377.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH1_k127_1342125_1	1096546.WYO_5203	2.118e-22	114.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R07A@1224|Proteobacteria,2UYK8@28211|Alphaproteobacteria,1JWQY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH1_k127_1343484_5	580332.Slit_2078	1.186e-67	239.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_1343484_8	65093.PCC7418_1588	4.193e-55	201.0	2EWKK@1|root,33PYP@2|Bacteria,1GC1A@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1343484_1	1173263.Syn7502_02619	6.382e-126	413.0	COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1H2TB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DTH1_k127_1343484_4	1198232.CYCME_1216	3.496e-74	255.0	COG1715@1|root,COG1715@2|Bacteria,1R2JZ@1224|Proteobacteria,1T5RK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1343484_10	215803.DB30_8826	2.985e-29	124.0	28H95@1|root,2Z7KY@2|Bacteria,1RA0C@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
DTH1_k127_1343484_7	272123.Anacy_0345	2.378e-59	213.0	COG5483@1|root,COG5483@2|Bacteria,1G5J1@1117|Cyanobacteria,1HP7V@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH1_k127_1343484_6	1121004.ATVC01000068_gene1663	2.528e-61	217.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,2VV76@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH1_k127_1343484_11	1121004.ATVC01000068_gene1664	1.158e-17	93.0	2DQR1@1|root,32UPK@2|Bacteria,1NKZE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1343484_2	765911.Thivi_0930	6.975e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_1343484_3	580332.Slit_2080	6.521e-75	272.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
DTH1_k127_1343484_0	497964.CfE428DRAFT_5498	2.11e-143	468.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	cefD	-	5.1.1.17	ko:K04127,ko:K11325,ko:K21174	ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130	M00673,M00825	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
DTH1_k127_1343484_9	1403819.BATR01000069_gene2016	2.965e-29	119.0	COG2197@1|root,COG2197@2|Bacteria,46U17@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_1356416_3	344747.PM8797T_02169	1.673e-94	332.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
DTH1_k127_1356416_5	203275.BFO_2526	2.607e-44	164.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,2FTDQ@200643|Bacteroidia,22Z1W@171551|Porphyromonadaceae	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
DTH1_k127_1356416_2	700598.Niako_3627	2.805e-133	433.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,1IVNN@117747|Sphingobacteriia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
DTH1_k127_1356416_0	313628.LNTAR_22814	1.355e-301	951.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
DTH1_k127_1356416_1	1454007.JAUG01000073_gene4094	6.362e-166	544.0	COG2247@1|root,COG2247@2|Bacteria,4P17J@976|Bacteroidetes	976|Bacteroidetes	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5013
DTH1_k127_1356416_4	1502724.FF80_02428	2.474e-44	179.0	COG3533@1|root,COG3533@2|Bacteria,1MWEN@1224|Proteobacteria,2U1Q4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
DTH1_k127_1358458_3	697282.Mettu_0535	5.529e-33	132.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DTH1_k127_1358458_0	1396141.BATP01000022_gene356	2.997e-98	333.0	COG0654@1|root,COG0654@2|Bacteria,46WJF@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DTH1_k127_1358458_1	1396141.BATP01000018_gene1534	6.256e-61	214.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc,Polyketide_cyc2
DTH1_k127_1358458_2	1869.MB27_10910	4.551e-48	175.0	COG1090@1|root,COG1090@2|Bacteria,2GU34@201174|Actinobacteria,4DH4S@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
DTH1_k127_1359169_2	1123242.JH636434_gene5414	4.719e-20	93.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH1_k127_1359169_0	583355.Caka_0779	3.457e-79	278.0	COG2304@1|root,COG2304@2|Bacteria,46SKE@74201|Verrucomicrobia,3K7H6@414999|Opitutae	414999|Opitutae	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
DTH1_k127_1359169_1	1167006.UWK_00742	2.24e-71	254.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
DTH1_k127_1362178_3	530564.Psta_4263	2.959e-25	110.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	psrP1	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHU_C,GSDH,Malectin
DTH1_k127_1362178_0	1123277.KB893176_gene3715	2.88e-230	722.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,SLH
DTH1_k127_1362178_2	521674.Plim_1676	1.586e-101	341.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH1_k127_1362178_1	1121904.ARBP01000013_gene349	1.078e-135	444.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
DTH1_k127_1362178_5	1540221.JQNI01000002_gene2916	3.26e-09	67.0	COG0491@1|root,COG0491@2|Bacteria,1WI41@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH1_k127_1362178_4	1121920.AUAU01000013_gene1721	2.676e-09	62.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH1_k127_1364559_0	1396141.BATP01000003_gene4967	3.506e-208	677.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
DTH1_k127_1364559_1	278963.ATWD01000001_gene2920	2.218e-179	569.0	2CK7V@1|root,2Z9WF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1364559_3	497964.CfE428DRAFT_6276	3.102e-73	266.0	COG2755@1|root,COG2755@2|Bacteria,46SVE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_1364559_2	1123508.JH636441_gene3126	6.022e-138	455.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_1368107_1	225937.HP15_1897	4.854e-63	249.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
DTH1_k127_1368107_0	118173.KB235914_gene3829	8.986e-102	374.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1368107_2	1121481.AUAS01000007_gene1191	8.01e-53	215.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF4091,Laminin_G_3,Lipase_GDSL_2,Peptidase_C25
DTH1_k127_136865_3	1123508.JH636439_gene1132	4.222e-13	76.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
DTH1_k127_136865_1	1120953.AUBH01000005_gene2232	5.16e-38	155.0	COG3595@1|root,COG3595@2|Bacteria,1RFCY@1224|Proteobacteria,1S5RB@1236|Gammaproteobacteria,467PX@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
DTH1_k127_136865_2	439235.Dalk_3988	9.421e-36	141.0	COG3809@1|root,COG3809@2|Bacteria,1QSA6@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
DTH1_k127_136865_0	1183438.GKIL_2151	4.216e-64	237.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DTH1_k127_1371328_5	1396141.BATP01000038_gene1208	5.797e-10	60.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH1_k127_1371328_1	1396141.BATP01000038_gene1207	1.658e-144	466.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia,2IVHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
DTH1_k127_1371328_2	1501230.ET33_33510	4.161e-91	312.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HACU@91061|Bacilli,26SWK@186822|Paenibacillaceae	91061|Bacilli	G	1,3--beta-D-glucan 3-glucanohydrolase	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CBM_4_9,Glyco_hydro_16,RicinB_lectin_2
DTH1_k127_1371328_4	1047013.AQSP01000097_gene1961	5.754e-31	132.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	mdmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
DTH1_k127_1371328_0	497964.CfE428DRAFT_1708	1.279e-168	539.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
DTH1_k127_1371328_3	903818.KI912268_gene822	3.485e-32	129.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
DTH1_k127_1371499_0	595460.RRSWK_04460	1.016e-67	234.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH1_k127_1371499_1	530564.Psta_3954	6.294e-61	221.0	COG4785@1|root,COG4785@2|Bacteria,2IZYN@203682|Planctomycetes	203682|Planctomycetes	S	May be involved in cell division	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16
DTH1_k127_1371499_2	1270193.JARP01000004_gene1522	2.744e-20	103.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,1I7I9@117743|Flavobacteriia,2NSYV@237|Flavobacterium	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
DTH1_k127_1384845_1	945713.IALB_2754	4.331e-85	299.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
DTH1_k127_1384845_0	497964.CfE428DRAFT_3359	3.892e-245	771.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
DTH1_k127_1384845_2	452637.Oter_2805	1.69e-54	193.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia,3K7A8@414999|Opitutae	414999|Opitutae	C	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DTH1_k127_1398517_1	794903.OPIT5_10630	6.504e-19	100.0	COG2133@1|root,COG3266@1|root,COG5184@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria,COG5184@2|Bacteria,46Z90@74201|Verrucomicrobia,3K9IV@414999|Opitutae	414999|Opitutae	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH1_k127_1398517_0	344747.PM8797T_02169	2.625e-94	327.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
DTH1_k127_1412345_4	481448.Minf_1754	1.71e-05	48.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia,37GAG@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
DTH1_k127_1412345_1	224325.AF_2211	5.756e-50	184.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
DTH1_k127_1412345_2	497964.CfE428DRAFT_5353	1.026e-35	151.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH1_k127_1412345_3	1219084.AP014508_gene1338	2.151e-13	82.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DTH1_k127_1412345_0	926560.KE387023_gene1701	1.771e-197	639.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH1_k127_1415717_1	326427.Cagg_3632	1.707e-65	230.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
DTH1_k127_1415717_0	452637.Oter_3464	2.443e-132	438.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
DTH1_k127_1417231_0	497964.CfE428DRAFT_3580	9.108e-224	700.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_1417231_2	497964.CfE428DRAFT_5946	4.243e-41	161.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_1417231_1	243233.MCA2756	5.009e-106	348.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
DTH1_k127_1418811_2	1123070.KB899251_gene725	5.481e-61	216.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia,2IU4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
DTH1_k127_1418811_1	1396418.BATQ01000015_gene4297	2.176e-81	284.0	COG2870@1|root,COG2870@2|Bacteria,46T1J@74201|Verrucomicrobia,2IVXQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
DTH1_k127_1418811_0	1396141.BATP01000009_gene2657	3.15e-128	414.0	COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia,2ITYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiazole biosynthesis protein ThiG	-	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
DTH1_k127_1418811_3	314256.OG2516_10581	4.585e-05	53.0	COG3637@1|root,COG3637@2|Bacteria,1RBBG@1224|Proteobacteria,2U5ED@28211|Alphaproteobacteria,2PE89@252301|Oceanicola	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	lpxQ	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl
DTH1_k127_1439015_4	497964.CfE428DRAFT_5038	1.338e-109	370.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DTH1_k127_1439015_12	497964.CfE428DRAFT_3571	2.133e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,46VJX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH1_k127_1439015_11	759914.BP951000_1517	8.379e-25	123.0	COG0457@1|root,COG0457@2|Bacteria	759914.BP951000_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1439015_10	497964.CfE428DRAFT_3654	2.55e-35	143.0	COG0576@1|root,COG0576@2|Bacteria,46T79@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH1_k127_1439015_2	382464.ABSI01000010_gene3750	1.169e-139	453.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH1_k127_1439015_6	497964.CfE428DRAFT_3657	6.529e-65	230.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
DTH1_k127_1439015_7	1396418.BATQ01000014_gene4333	6.744e-58	216.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,2IU90@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
DTH1_k127_1439015_3	1304888.ATWF01000001_gene1852	1.966e-128	420.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH1_k127_1439015_1	56780.SYN_00126	1.681e-157	505.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH1_k127_1439015_13	497964.CfE428DRAFT_5639	1.367e-12	74.0	COG0745@1|root,COG0745@2|Bacteria	497964.CfE428DRAFT_5639|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1439015_5	667014.Thein_0763	3.656e-74	258.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
DTH1_k127_1439015_8	1123070.KB899253_gene998	6.359e-54	201.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,2IUD8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NAD_kinase
DTH1_k127_1439015_9	1225184.ALXE01000044_gene644	1.267e-53	203.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN8T@1236|Gammaproteobacteria,3VZKY@53335|Pantoea	1236|Gammaproteobacteria	K	Transcriptional regulator	cytR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
DTH1_k127_1439015_14	1403819.BATR01000042_gene1260	2.485e-10	67.0	COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N,T2SSG
DTH1_k127_1439015_0	794903.OPIT5_16815	1.597e-166	527.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,3K7UQ@414999|Opitutae	414999|Opitutae	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DTH1_k127_1445443_1	521674.Plim_1879	1.433e-113	385.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH1_k127_1445443_2	1304872.JAGC01000003_gene2354	5.749e-67	248.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
DTH1_k127_1445443_0	1249627.D779_1354	1.659e-122	409.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
DTH1_k127_1453322_4	1267535.KB906767_gene4834	3.172e-29	130.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
DTH1_k127_1453322_2	344747.PM8797T_24141	4.089e-130	426.0	COG1520@1|root,COG1520@2|Bacteria,2IYK2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_1453322_3	1396418.BATQ01000132_gene3982	2.793e-102	346.0	COG1250@1|root,COG1250@2|Bacteria,46TNQ@74201|Verrucomicrobia,2IWBJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1453322_1	1123508.JH636448_gene7659	6.355e-200	629.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
DTH1_k127_1453322_0	452637.Oter_3479	0.0	1022.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
DTH1_k127_1471188_9	794903.OPIT5_03390	1.145e-31	124.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
DTH1_k127_1471188_2	1396418.BATQ01000136_gene3697	9.311e-289	899.0	COG0665@1|root,COG0665@2|Bacteria,46TKJ@74201|Verrucomicrobia,2IWQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH1_k127_1471188_11	595460.RRSWK_04460	7.081e-26	108.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH1_k127_1471188_13	330214.NIDE2936	5.49e-19	89.0	COG1598@1|root,COG1598@2|Bacteria,3J1EZ@40117|Nitrospirae	40117|Nitrospirae	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1471188_14	589924.Ferp_2052	8.694e-19	91.0	arCOG03086@1|root,arCOG03086@2157|Archaea,2Y7EV@28890|Euryarchaeota,247AD@183980|Archaeoglobi	183980|Archaeoglobi	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DTH1_k127_1471188_7	309799.DICTH_0179	6.057e-64	237.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
DTH1_k127_1471188_6	383372.Rcas_1067	1.105e-73	256.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
DTH1_k127_1471188_0	497964.CfE428DRAFT_4373	0.0	1112.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DTH1_k127_1471188_1	278957.ABEA03000202_gene4301	0.0	1073.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH1_k127_1471188_8	1142394.PSMK_14730	7.353e-56	207.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH1_k127_1471188_4	497964.CfE428DRAFT_4175	8.438e-87	296.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_1471188_10	1403819.BATR01000069_gene2089	2.035e-29	125.0	COG4968@1|root,COG4968@2|Bacteria,46VT8@74201|Verrucomicrobia,2IW29@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH1_k127_1471188_15	794903.OPIT5_29655	4.501e-10	71.0	COG4968@1|root,COG4968@2|Bacteria	794903.OPIT5_29655|-	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1471188_12	497964.CfE428DRAFT_4171	3.29e-20	98.0	2ETM2@1|root,33M4S@2|Bacteria,46WNN@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1471188_3	1396418.BATQ01000076_gene732	1.831e-141	465.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,2ITXY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DTH1_k127_1471188_5	452637.Oter_3825	2.035e-86	292.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,3K7RD@414999|Opitutae	414999|Opitutae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
DTH1_k127_1482360_0	497964.CfE428DRAFT_0593	1.606e-139	462.0	COG3666@1|root,COG3666@2|Bacteria,46S8M@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
DTH1_k127_1483205_1	1121924.ATWH01000017_gene3159	3.649e-32	145.0	COG3408@1|root,COG3408@2|Bacteria,2GYU2@201174|Actinobacteria,4FR4D@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl-hydrolase family 116, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DUF608
DTH1_k127_1483205_0	1028800.RG540_PA04370	3.008e-86	315.0	COG5652@1|root,COG5652@2|Bacteria,1MX6C@1224|Proteobacteria,2U18Q@28211|Alphaproteobacteria,4BBZB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
DTH1_k127_1483205_2	91604.ID47_04525	2.385e-26	115.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,47F9T@766|Rickettsiales	766|Rickettsiales	G	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DTH1_k127_1489233_1	697281.Mahau_0407	3.569e-70	257.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH1_k127_1489233_0	497964.CfE428DRAFT_4093	0.0	1283.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia	74201|Verrucomicrobia	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
DTH1_k127_1489608_1	1348663.KCH_70110	2.167e-44	164.0	COG1090@1|root,COG1090@2|Bacteria,2GU34@201174|Actinobacteria,2M17T@2063|Kitasatospora	201174|Actinobacteria	S	overlaps another CDS with the same product name	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
DTH1_k127_1489608_2	1396418.BATQ01000041_gene6305	4.091e-24	115.0	COG2010@1|root,COG2010@2|Bacteria,46T74@74201|Verrucomicrobia,2IWN4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH1_k127_1489608_0	1396141.BATP01000018_gene1534	1.089e-63	222.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc,Polyketide_cyc2
DTH1_k127_1500494_4	521674.Plim_0128	4.711e-117	386.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
DTH1_k127_1500494_2	521674.Plim_0129	4.807e-175	581.0	COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,2IY3X@203682|Planctomycetes	203682|Planctomycetes	CL	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
DTH1_k127_1500494_1	886293.Sinac_0942	1.665e-224	705.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH1_k127_1500494_6	448385.sce0162	1.902e-47	182.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH1_k127_1500494_3	595460.RRSWK_05849	1.71e-137	455.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,2J2W6@203682|Planctomycetes	203682|Planctomycetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
DTH1_k127_1500494_0	595460.RRSWK_06189	8.752e-262	832.0	COG1894@1|root,COG1894@2|Bacteria,2IXJ8@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
DTH1_k127_1500494_5	497964.CfE428DRAFT_5712	3.838e-116	398.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_1500494_7	595460.RRSWK_06187	3.844e-44	169.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_5
DTH1_k127_1510385_2	1123508.JH636450_gene7203	5.642e-85	290.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Laminin_G_3
DTH1_k127_1510385_0	314230.DSM3645_25492	5.007e-96	329.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_1510385_1	595460.RRSWK_04460	4.667e-94	316.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH1_k127_1512232_1	395961.Cyan7425_0748	5.016e-52	186.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH1_k127_1512232_0	1173027.Mic7113_4161	1.162e-168	586.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
DTH1_k127_1540930_1	313628.LNTAR_20062	6.452e-09	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_1540930_0	382464.ABSI01000013_gene1723	4.253e-109	383.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
DTH1_k127_155200_2	1131269.AQVV01000100_gene2556	1.254e-16	89.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_155200_1	243233.MCA2161	1.358e-166	548.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_155200_0	640081.Dsui_0821	2.636e-297	932.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
DTH1_k127_1560397_0	1173024.KI912153_gene315	1.49e-204	644.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1JIBX@1189|Stigonemataceae	1117|Cyanobacteria	E	Glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
DTH1_k127_1560397_1	1122185.N792_05380	2.248e-147	477.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1X35C@135614|Xanthomonadales	135614|Xanthomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
DTH1_k127_1560397_2	398512.JQKC01000010_gene143	1.96e-108	368.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH1_k127_1560397_3	794903.OPIT5_05545	2.157e-73	251.0	COG0306@1|root,COG0306@2|Bacteria,46SDP@74201|Verrucomicrobia,3K7HD@414999|Opitutae	414999|Opitutae	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DTH1_k127_1560749_5	196162.Noca_4116	1.646e-08	58.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
DTH1_k127_1560749_6	1192034.CAP_6765	1.663e-05	51.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	-	ko:K21781	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002	-	-	-	PP-binding
DTH1_k127_1560749_4	1116472.MGMO_20c00250	1.042e-20	106.0	COG1020@1|root,COG1020@2|Bacteria,1NK69@1224|Proteobacteria,1SKZR@1236|Gammaproteobacteria,1XFVG@135618|Methylococcales	135618|Methylococcales	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1560749_3	933262.AXAM01000001_gene381	3.742e-35	154.0	COG0644@1|root,COG0644@2|Bacteria,1QM8G@1224|Proteobacteria	1224|Proteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH1_k127_1560749_0	338966.Ppro_0910	3.41e-103	354.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42QET@68525|delta/epsilon subdivisions,2WIZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DTH1_k127_1560749_1	1123008.KB905694_gene1758	6.929e-74	268.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,2FQIT@200643|Bacteroidia,22X2B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
DTH1_k127_1560749_2	1249975.JQLP01000005_gene2306	1.176e-66	258.0	COG4258@1|root,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1HYZW@117743|Flavobacteriia,2P5PX@244698|Gillisia	976|Bacteroidetes	I	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
DTH1_k127_1566591_3	102125.Xen7305DRAFT_00040820	5.939e-61	225.0	COG1305@1|root,COG1305@2|Bacteria,1G1YY@1117|Cyanobacteria,3VKRN@52604|Pleurocapsales	1117|Cyanobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH1_k127_1566591_7	382464.ABSI01000010_gene3682	1.82e-18	97.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DTH1_k127_1566591_6	935948.KE386495_gene2110	1.202e-37	144.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GS3@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH1_k127_1566591_5	247490.KSU1_C0572	3.963e-45	175.0	COG0115@1|root,COG0115@2|Bacteria,2J20K@203682|Planctomycetes	203682|Planctomycetes	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
DTH1_k127_1566591_0	1122947.FR7_2048	6.301e-107	363.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4H6Y8@909932|Negativicutes	909932|Negativicutes	EH	Anthranilate synthase component I, N terminal region	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH1_k127_1566591_2	861299.J421_0058	5.964e-67	238.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH1_k127_1566591_1	521045.Kole_0981	1.242e-78	275.0	COG0524@1|root,COG0524@2|Bacteria,2GDS1@200918|Thermotogae	200918|Thermotogae	H	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH1_k127_1566591_4	1035193.HMPREF9073_03223	1.503e-48	179.0	COG2271@1|root,COG2271@2|Bacteria,4NGX4@976|Bacteroidetes,1I4JV@117743|Flavobacteriia	976|Bacteroidetes	G	Major Facilitator Superfamily	glpT	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
DTH1_k127_1568345_3	1485544.JQKP01000003_gene284	3.632e-08	67.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
DTH1_k127_1568345_1	478741.JAFS01000001_gene1166	1.826e-24	120.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia,37FXR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH1_k127_1568345_0	580331.Thit_1828	4.309e-25	120.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,42FP0@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC-type uncharacterised transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
DTH1_k127_1568345_2	1123508.JH636448_gene7558	1.655e-17	86.0	COG1277@1|root,COG1277@2|Bacteria,2J0HW@203682|Planctomycetes	203682|Planctomycetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH1_k127_1600262_1	1906.SFRA_03940	1.112e-15	85.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH1_k127_1600262_0	1121106.JQKB01000056_gene5865	1.686e-122	409.0	28MUA@1|root,2ZB28@2|Bacteria,1R8RF@1224|Proteobacteria	1224|Proteobacteria	S	Capsule biosynthesis CapC	-	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
DTH1_k127_1601804_0	1123242.JH636435_gene793	8.011e-183	584.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DTH1_k127_1601804_2	1499967.BAYZ01000171_gene5584	5.867e-125	409.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_1601804_4	1300345.LF41_1322	1.524e-99	336.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1S5WE@1236|Gammaproteobacteria,1X3ZI@135614|Xanthomonadales	135614|Xanthomonadales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH1_k127_1601804_8	497964.CfE428DRAFT_2483	6.467e-66	235.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH1_k127_1601804_7	497964.CfE428DRAFT_1729	8.788e-72	248.0	COG0122@1|root,COG0122@2|Bacteria,46V2J@74201|Verrucomicrobia	74201|Verrucomicrobia	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
DTH1_k127_1601804_9	583355.Caka_1102	2.309e-37	149.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH1_k127_1601804_5	497964.CfE428DRAFT_3666	4.147e-92	311.0	COG1409@1|root,COG1409@2|Bacteria,46TUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH1_k127_1601804_6	192952.MM_1779	6.856e-74	254.0	COG1926@1|root,arCOG06847@2157|Archaea,2XWRW@28890|Euryarchaeota,2NABG@224756|Methanomicrobia	224756|Methanomicrobia	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
DTH1_k127_1601804_3	555779.Dthio_PD2105	4.368e-117	384.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,43B03@68525|delta/epsilon subdivisions,2X6E6@28221|Deltaproteobacteria,2MH1Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
DTH1_k127_1601804_1	999419.HMPREF1077_00773	1.035e-125	416.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,2FTQH@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_1604392_3	324057.Pjdr2_4676	8.122e-19	102.0	COG1409@1|root,COG3291@1|root,COG3537@1|root,COG3693@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG3537@2|Bacteria,COG3693@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,26VY4@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_92
DTH1_k127_1604392_1	1396141.BATP01000043_gene1929	1.184e-35	158.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_1604392_0	1396141.BATP01000042_gene1928	7.004e-40	171.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_1604392_2	1123508.JH636442_gene4323	1.893e-25	115.0	COG4409@1|root,COG4932@1|root,COG4409@2|Bacteria,COG4932@2|Bacteria,2J4JQ@203682|Planctomycetes	203682|Planctomycetes	M	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1620161_4	497964.CfE428DRAFT_2131	2.716e-22	100.0	29NX7@1|root,309VB@2|Bacteria,46WPG@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1620161_3	1128421.JAGA01000002_gene1111	2.018e-29	123.0	COG0622@1|root,COG0622@2|Bacteria,2NQ04@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
DTH1_k127_1620161_2	483219.LILAB_36295	1.421e-44	180.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH1_k127_1620161_1	313628.LNTAR_05744	1.944e-85	301.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH1_k127_1620161_0	204669.Acid345_4052	2.532e-308	962.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
DTH1_k127_1624292_2	509191.AEDB02000067_gene820	1.52e-47	177.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHXD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
DTH1_k127_1624292_1	497964.CfE428DRAFT_6353	7.236e-82	281.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
DTH1_k127_1624292_0	497964.CfE428DRAFT_6354	2.821e-92	309.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
DTH1_k127_1624292_3	1184267.A11Q_876	6.144e-15	76.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2MT6A@213481|Bdellovibrionales,2WN8K@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
DTH1_k127_1633541_0	382464.ABSI01000013_gene1549	5.648e-125	425.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH1_k127_1633541_1	583355.Caka_0634	6.167e-13	82.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.178	ko:K20830	-	-	-	-	ko00000,ko01000	-	GH16	-	CBM_2,CBM_4_9,CBM_6,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_76,Glyco_hydro_81,Laminin_G_3,RicinB_lectin_2
DTH1_k127_1634231_0	344747.PM8797T_05400	3.197e-82	289.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_1634231_1	1267535.KB906767_gene241	1.327e-69	267.0	COG3345@1|root,COG3345@2|Bacteria,3Y3UB@57723|Acidobacteria,2JKQN@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Glycoside hydrolase, clan GH-D	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
DTH1_k127_1634231_2	67281.JNZZ01000017_gene6006	1.306e-14	89.0	COG0366@1|root,COG3345@1|root,COG0366@2|Bacteria,COG3345@2|Bacteria,2HEIR@201174|Actinobacteria,419QT@629295|Streptomyces griseus group	201174|Actinobacteria	G	Glycosyl hydrolase 101 beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_101C,Glyco_hydro_101,NPCBM,NPCBM_assoc
DTH1_k127_1648384_6	690850.Desaf_0024	8.695e-53	190.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MHBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH1_k127_1648384_4	690850.Desaf_0021	3.037e-61	226.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2MG43@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH1_k127_1648384_7	1485545.JQLW01000005_gene1063	1.202e-42	165.0	COG2227@1|root,COG2227@2|Bacteria,1QY24@1224|Proteobacteria	1224|Proteobacteria	H	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
DTH1_k127_1648384_0	926549.KI421517_gene437	5.156e-84	285.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,SAM_MT
DTH1_k127_1648384_8	756067.MicvaDRAFT_4986	1.55e-10	73.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
DTH1_k127_1648384_5	402881.Plav_1911	5.442e-57	215.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Cons_hypoth95,SAM_MT
DTH1_k127_1648384_9	1167006.UWK_02438	1.154e-05	57.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH,EcKinase,HMG-CoA_red
DTH1_k127_1648384_3	880072.Desac_2043	5.002e-70	252.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria,2MRJ3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH1_k127_1648384_1	335543.Sfum_3152	1.661e-80	275.0	COG0500@1|root,COG2226@2|Bacteria,1NGTM@1224|Proteobacteria	1224|Proteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH1_k127_1648384_2	497964.CfE428DRAFT_3065	1.132e-71	250.0	2F2JH@1|root,33VGF@2|Bacteria	2|Bacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH1_k127_1651521_1	439235.Dalk_2653	1.696e-67	241.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MPU9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH1_k127_1651521_3	530564.Psta_1718	6.164e-23	101.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DTH1_k127_1651521_2	497964.CfE428DRAFT_6239	4.062e-53	188.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
DTH1_k127_1651521_0	497964.CfE428DRAFT_2289	5.908e-99	334.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DTH1_k127_1654693_1	1123242.JH636435_gene944	1.882e-108	370.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_1654693_2	497964.CfE428DRAFT_0215	1.901e-58	213.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
DTH1_k127_1654693_3	1303518.CCALI_02394	3.073e-15	86.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_1654693_4	1303518.CCALI_00378	7.723e-15	84.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_1654693_0	497964.CfE428DRAFT_4557	4.871e-166	531.0	COG2133@1|root,COG2133@2|Bacteria,46U0G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1655840_0	867903.ThesuDRAFT_00190	1.355e-74	265.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WCJP@538999|Clostridiales incertae sedis	186801|Clostridia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DTH1_k127_1655840_4	1177154.Y5S_00007	8.499e-14	83.0	2FA92@1|root,342HR@2|Bacteria,1NYCG@1224|Proteobacteria,1SQ6S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1655840_2	1121468.AUBR01000001_gene497	1.102e-52	194.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
DTH1_k127_1655840_1	864702.OsccyDRAFT_0533	1.328e-71	253.0	COG1043@1|root,COG1043@2|Bacteria,1G3IU@1117|Cyanobacteria,1H8PD@1150|Oscillatoriales	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH1_k127_1655840_3	62928.azo1562	1.771e-49	186.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,2KVAD@206389|Rhodocyclales	206389|Rhodocyclales	H	Molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DTH1_k127_1667650_3	338966.Ppro_2636	3.22e-06	57.0	COG3637@1|root,COG3637@2|Bacteria,1NGKR@1224|Proteobacteria,42XMD@68525|delta/epsilon subdivisions,2WSIW@28221|Deltaproteobacteria,43UMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH1_k127_1667650_0	290315.Clim_0430	1.471e-93	324.0	COG1409@1|root,COG1785@1|root,COG2931@1|root,COG3391@1|root,COG1409@2|Bacteria,COG1785@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1FDAF@1090|Chlorobi	1090|Chlorobi	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,SWM_repeat
DTH1_k127_1667650_1	886293.Sinac_4026	2.145e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH1_k127_1667650_2	1449049.JONW01000008_gene340	1.795e-37	146.0	COG2730@1|root,COG2730@2|Bacteria,1N2XP@1224|Proteobacteria,2TSHY@28211|Alphaproteobacteria,2KIB4@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH1_k127_1678251_2	1396141.BATP01000032_gene4314	3.261e-92	315.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH1_k127_1678251_6	349521.HCH_00950	2.466e-23	109.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DTH1_k127_1678251_7	324602.Caur_3413	2.115e-14	87.0	COG0497@1|root,COG1196@1|root,COG0497@2|Bacteria,COG1196@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1678251_1	886293.Sinac_2616	3.195e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH1_k127_1678251_0	1121440.AUMA01000005_gene2707	8.964e-136	441.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2WNAF@28221|Deltaproteobacteria,2M9I9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
DTH1_k127_1678251_4	177437.HRM2_24220	4.509e-55	200.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_1678251_3	378806.STAUR_4743	4.985e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,43A1N@68525|delta/epsilon subdivisions,2X25S@28221|Deltaproteobacteria,2YYJ4@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase dehydratase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH1_k127_1678251_5	641524.ADICYQ_0788	3.394e-25	107.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_1688605_1	1267534.KB906758_gene2376	5.194e-198	627.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_1688605_0	1123276.KB893270_gene4720	2.937e-200	635.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,47KJR@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_1688605_2	497964.CfE428DRAFT_0793	1.189e-74	253.0	COG0450@1|root,COG0450@2|Bacteria,46STI@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH1_k127_1688605_3	1173025.GEI7407_2938	5.041e-11	63.0	COG1225@1|root,COG1225@2|Bacteria,1G6AA@1117|Cyanobacteria,1HBBD@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH1_k127_1689116_1	1403819.BATR01000002_gene28	7.113e-155	500.0	COG1253@1|root,COG1253@2|Bacteria,46U7J@74201|Verrucomicrobia,2IVE3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DTH1_k127_1689116_4	756272.Plabr_1391	3.359e-79	275.0	COG1082@1|root,COG1082@2|Bacteria,2IXXX@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
DTH1_k127_1689116_0	452637.Oter_0071	9.429e-221	713.0	COG3127@1|root,COG3127@2|Bacteria,46UKQ@74201|Verrucomicrobia,3K7U2@414999|Opitutae	414999|Opitutae	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_1689116_3	1121957.ATVL01000008_gene3992	2.038e-93	313.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_1689116_6	517418.Ctha_1767	2.322e-67	237.0	COG2755@1|root,COG2755@2|Bacteria,1FET3@1090|Chlorobi	1090|Chlorobi	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
DTH1_k127_1689116_5	344747.PM8797T_07504	6.24e-71	250.0	COG0428@1|root,COG0428@2|Bacteria,2IZ3C@203682|Planctomycetes	203682|Planctomycetes	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
DTH1_k127_1689116_7	1303518.CCALI_02381	2.278e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_1689116_2	1449126.JQKL01000015_gene2921	3.582e-138	451.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,26865@186813|unclassified Clostridiales	186801|Clostridia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DTH1_k127_1689116_9	858619.CVAR_1175	4.195e-09	68.0	2DBMC@1|root,2Z9YC@2|Bacteria,2IR9W@201174|Actinobacteria,22M4K@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1699631_1	497964.CfE428DRAFT_1053	6.964e-82	279.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH1_k127_1699631_0	1123508.JH636439_gene1370	3.713e-193	622.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
DTH1_k127_1699631_2	1396141.BATP01000022_gene421	1.018e-57	214.0	2BVGP@1|root,32QVG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_170684_3	1385935.N836_35430	1.867e-22	100.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_170684_4	749414.SBI_05800	2.435e-05	51.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria	201174|Actinobacteria	L	DNA replication protein	-	-	-	ko:K02315,ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
DTH1_k127_170684_2	880072.Desac_0910	5.02e-31	128.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria	1224|Proteobacteria	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HTH_31,HsdM_N,N6_Mtase
DTH1_k127_170684_1	1192034.CAP_5127	4.897e-33	146.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,4341P@68525|delta/epsilon subdivisions,2X4PD@28221|Deltaproteobacteria,2YZCK@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
DTH1_k127_170684_0	661478.OP10G_0514	1.492e-233	753.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,F5_F8_type_C,Lactonase,Phosphoesterase
DTH1_k127_1712598_1	497964.CfE428DRAFT_1935	9.381e-130	422.0	COG2870@1|root,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,Hydrolase,PfkB
DTH1_k127_1712598_0	1123242.JH636434_gene3161	1.214e-151	488.0	COG1915@1|root,COG1915@2|Bacteria,2IXX9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1712598_2	1499967.BAYZ01000068_gene1935	1.488e-72	274.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
DTH1_k127_1712598_3	498761.HM1_0137	1.3e-30	141.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
DTH1_k127_1719571_3	595460.RRSWK_06263	5.237e-41	169.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH1_k127_1719571_4	1047013.AQSP01000114_gene693	6.43e-28	119.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1719571_1	497964.CfE428DRAFT_3356	3.103e-118	399.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,46TMH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
DTH1_k127_1719571_0	497964.CfE428DRAFT_2607	3.1e-133	431.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH1_k127_1719571_2	1521187.JPIM01000042_gene1869	5.637e-56	202.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,375J4@32061|Chloroflexia	32061|Chloroflexia	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DTH1_k127_1719571_5	497964.CfE428DRAFT_2605	1.125e-13	70.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
DTH1_k127_1744597_0	452637.Oter_1389	7.369e-150	515.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_1748793_2	1043205.AFYF01000030_gene487	3.903e-13	85.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
DTH1_k127_1748793_4	1250005.PHEL85_0454	3.051e-08	68.0	COG1404@1|root,COG2312@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2312@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,3VX3A@52959|Polaribacter	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH1_k127_1748793_0	351160.RRC213	5.93e-67	262.0	COG3391@1|root,arCOG02544@1|root,arCOG02544@2157|Archaea,arCOG02562@2157|Archaea,2Y7T2@28890|Euryarchaeota,2NBM7@224756|Methanomicrobia	224756|Methanomicrobia	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
DTH1_k127_1748793_3	879243.Poras_0890	1.485e-09	73.0	COG3630@1|root,COG3630@2|Bacteria,4NIHN@976|Bacteroidetes,2FMSV@200643|Bacteroidia,22W1S@171551|Porphyromonadaceae	976|Bacteroidetes	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,OAD_gamma
DTH1_k127_1748793_1	1396141.BATP01000043_gene1929	4.826e-42	180.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_174900_1	313612.L8106_20308	7.199e-86	296.0	COG4301@1|root,COG4301@2|Bacteria,1G4VW@1117|Cyanobacteria,1HF60@1150|Oscillatoriales	1117|Cyanobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
DTH1_k127_174900_6	1279038.KB907352_gene2224	3.809e-31	128.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,2UJ8D@28211|Alphaproteobacteria,2JX8I@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
DTH1_k127_174900_7	478741.JAFS01000002_gene875	1.723e-30	129.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH1_k127_174900_4	497964.CfE428DRAFT_2235	7.857e-69	242.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
DTH1_k127_174900_8	1396141.BATP01000045_gene1834	4.483e-08	60.0	2DR0H@1|root,339NS@2|Bacteria,46ZIA@74201|Verrucomicrobia,2IUYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
DTH1_k127_174900_2	481448.Minf_1950	1.248e-85	291.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH1_k127_174900_0	234267.Acid_5590	5.986e-161	527.0	COG0843@1|root,COG0843@2|Bacteria,3Y2NS@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DTH1_k127_174900_3	234267.Acid_4382	7.255e-76	265.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DTH1_k127_174900_5	478741.JAFS01000001_gene1116	5.053e-65	239.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
DTH1_k127_175546_3	702438.HMPREF9431_00108	1.445e-21	101.0	COG1569@1|root,COG1569@2|Bacteria,4NSS3@976|Bacteroidetes,2FTP8@200643|Bacteroidia	976|Bacteroidetes	S	toxin-antitoxin system toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
DTH1_k127_175546_0	497964.CfE428DRAFT_1743	2.211e-268	840.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
DTH1_k127_175546_1	497964.CfE428DRAFT_0749	2.987e-88	299.0	COG0327@1|root,COG0327@2|Bacteria	2|Bacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
DTH1_k127_175546_4	497964.CfE428DRAFT_6193	8.828e-07	58.0	2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_175546_2	880072.Desac_1280	1.137e-49	183.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MQGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH1_k127_1755788_1	75379.Tint_2570	1.253e-25	108.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VK17@28216|Betaproteobacteria,1KK0X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH1_k127_1755788_0	398512.JQKC01000004_gene5249	6.634e-154	519.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH1_k127_1756611_1	1123242.JH636434_gene4299	3.934e-77	275.0	COG2755@1|root,COG2755@2|Bacteria,2IZUG@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_1756611_4	1118059.CAHC01000003_gene959	2.304e-08	63.0	COG0507@1|root,COG0507@2|Bacteria,1V27I@1239|Firmicutes,24GPP@186801|Clostridia	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1756611_6	1396141.BATP01000060_gene4629	7.066e-05	46.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia,2IU0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
DTH1_k127_1756611_2	443144.GM21_2431	1.848e-27	133.0	COG1572@1|root,COG1657@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG4733@1|root,COG1572@2|Bacteria,COG1657@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
DTH1_k127_1756611_0	696747.NIES39_C05180	6.82e-81	310.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
DTH1_k127_1756611_7	867845.KI911784_gene2206	0.0002414	56.0	COG1716@1|root,COG3391@1|root,COG4733@1|root,COG1716@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	2.7.11.1,3.2.1.78	ko:K01218,ko:K12132	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01001	-	GH26	-	FHA,NHL,PA14,fn3
DTH1_k127_1756611_5	1502851.FG93_00043	3.339e-07	66.0	COG1404@1|root,COG2931@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1QYHZ@1224|Proteobacteria,2UHT4@28211|Alphaproteobacteria,3K04W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
DTH1_k127_1756611_3	856793.MICA_148	4.848e-13	85.0	COG1520@1|root,COG1520@2|Bacteria,1R0E4@1224|Proteobacteria,2UJBQ@28211|Alphaproteobacteria,4BSD7@82117|unclassified Alphaproteobacteria	1224|Proteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
DTH1_k127_1791638_2	886293.Sinac_1763	6.639e-129	424.0	COG1830@1|root,COG1830@2|Bacteria,2IXP8@203682|Planctomycetes	203682|Planctomycetes	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1791638_0	1121017.AUFG01000010_gene1661	1.413e-174	557.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4FEQ1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DTH1_k127_1791638_3	1173028.ANKO01000195_gene5986	2.489e-104	350.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
DTH1_k127_1791638_1	382464.ABSI01000011_gene3117	9.604e-149	475.0	COG0074@1|root,COG0074@2|Bacteria,46TRM@74201|Verrucomicrobia,2ITVZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
DTH1_k127_1791638_4	497964.CfE428DRAFT_4129	6.604e-41	155.0	COG0346@1|root,COG0346@2|Bacteria,46T5V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH1_k127_1791638_5	278957.ABEA03000013_gene2636	1.282e-32	127.0	COG0045@1|root,COG0045@2|Bacteria,46TDG@74201|Verrucomicrobia,3K7AB@414999|Opitutae	414999|Opitutae	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DTH1_k127_1810913_0	909663.KI867150_gene1425	1.669e-97	323.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DTH1_k127_1810913_1	1220534.B655_1532	4.486e-21	102.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH1_k127_1824604_1	909663.KI867150_gene1086	2.353e-64	231.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_1824604_0	404589.Anae109_0137	1.854e-74	269.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
DTH1_k127_1825210_2	596324.TREVI0001_1041	8.824e-11	75.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Collagen,DUF4347,PPC,RHS_repeat,SdrD_B,VWD
DTH1_k127_1825210_0	1403819.BATR01000125_gene4494	3.635e-173	580.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH1_k127_1825210_1	485918.Cpin_3102	5.583e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_1825210_3	906968.Trebr_0705	0.000154	49.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,2J6UE@203691|Spirochaetes	203691|Spirochaetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
DTH1_k127_183310_3	1121403.AUCV01000010_gene1383	1.824e-46	177.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
DTH1_k127_183310_0	1403819.BATR01000067_gene2010	6.61e-148	472.0	COG2326@1|root,COG2326@2|Bacteria,46UWN@74201|Verrucomicrobia,2IVFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
DTH1_k127_183310_1	204669.Acid345_4072	9.892e-122	411.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
DTH1_k127_183310_2	1122603.ATVI01000007_gene1570	5.084e-80	273.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales	135614|Xanthomonadales	V	Efflux pump membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH1_k127_1849774_0	583355.Caka_0705	1.986e-151	486.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_1849774_3	579405.Dd703_0239	1.218e-77	269.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,2JCM1@204037|Dickeya	1236|Gammaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
DTH1_k127_1849774_1	1123070.KB899255_gene1382	1.074e-123	417.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,2ITRD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DHHA1 domain	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH1_k127_1849774_2	867845.KI911784_gene850	1.566e-79	273.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
DTH1_k127_1857499_8	379066.GAU_2005	5.117e-53	194.0	COG1301@1|root,COG1301@2|Bacteria,1ZT91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
DTH1_k127_1857499_5	1382356.JQMP01000004_gene323	5.322e-88	301.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
DTH1_k127_1857499_7	1396141.BATP01000057_gene2952	3.312e-72	256.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DTH1_k127_1857499_4	1414720.CBYM010000003_gene388	3.968e-97	329.0	COG0524@1|root,COG0524@2|Bacteria,1V4QY@1239|Firmicutes,24HRA@186801|Clostridia,36S3G@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH1_k127_1857499_9	497964.CfE428DRAFT_6518	1.163e-49	193.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DTH1_k127_1857499_0	344747.PM8797T_13063	2.516e-171	552.0	COG3119@1|root,COG3119@2|Bacteria,2IXUN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_1857499_1	1123242.JH636434_gene3814	3.959e-146	475.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_1857499_2	95619.PM1_0204860	6.673e-132	433.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280	Aldedh
DTH1_k127_1857499_11	388467.A19Y_2770	0.0001133	51.0	COG4636@1|root,COG4636@2|Bacteria,1G4JH@1117|Cyanobacteria,1H9Q5@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DTH1_k127_1857499_3	497964.CfE428DRAFT_4568	4.255e-129	429.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1857499_6	945713.IALB_0134	4.734e-85	299.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
DTH1_k127_1857499_10	408672.NBCG_05273	1.156e-07	65.0	COG1749@1|root,COG1749@2|Bacteria,2I2X3@201174|Actinobacteria	201174|Actinobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,Mo-co_dimer,fn3
DTH1_k127_1864055_0	525904.Tter_2007	4.504e-111	379.0	2CB42@1|root,2Z7Y3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1864055_1	761193.Runsl_3635	1.731e-74	263.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	HemolysinCabind,PD40
DTH1_k127_1875638_1	700598.Niako_1079	1.164e-10	64.0	COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,4NHK1@976|Bacteroidetes,1J0FS@117747|Sphingobacteriia	976|Bacteroidetes	L	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
DTH1_k127_1875638_0	1487953.JMKF01000078_gene4088	1.132e-53	198.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
DTH1_k127_1894905_0	864702.OsccyDRAFT_2745	5.465e-109	404.0	COG2931@1|root,COG2931@2|Bacteria,1GHDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH1_k127_1894905_5	929703.KE386491_gene2364	1.727e-06	64.0	COG2373@1|root,COG3209@1|root,COG3291@1|root,COG4386@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,COG4932@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH1_k127_1894905_3	929556.Solca_2367	1.97e-42	183.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,HemolysinCabind,IgGFc_binding
DTH1_k127_1894905_2	1173263.Syn7502_00897	1.418e-79	306.0	COG2931@1|root,COG3210@1|root,COG3386@1|root,COG5276@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG5276@2|Bacteria,1G1I0@1117|Cyanobacteria,1H1YG@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG2931 RTX toxins and related Ca2 -binding proteins	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,P_proprotein,Peptidase_S8
DTH1_k127_1894905_1	96561.Dole_1791	3.853e-80	292.0	COG1044@1|root,COG1361@1|root,COG1653@1|root,COG1044@2|Bacteria,COG1361@2|Bacteria,COG1653@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1894905_4	313606.M23134_07854	1.605e-07	64.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,47U5Y@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
DTH1_k127_1907310_1	402777.KB235903_gene2334	1.855e-78	276.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1H72B@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
DTH1_k127_1907310_4	382464.ABSI01000020_gene148	6.704e-07	57.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
DTH1_k127_1907310_0	269797.Mbar_A1995	9.821e-115	387.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
DTH1_k127_1907310_3	485913.Krac_7095	7.867e-10	67.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
DTH1_k127_1907310_5	1353531.AZNX01000014_gene3212	0.0003267	46.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,2U26E@28211|Alphaproteobacteria,4BCIN@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
DTH1_k127_1907310_2	380394.Lferr_0309	4.171e-74	265.0	COG5433@1|root,COG5433@2|Bacteria,1RAHU@1224|Proteobacteria,1S1TZ@1236|Gammaproteobacteria,2NDWK@225057|Acidithiobacillales	1236|Gammaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
DTH1_k127_1909759_2	1396418.BATQ01000083_gene1173	8.486e-54	199.0	COG0438@1|root,COG0438@2|Bacteria,46ZHN@74201|Verrucomicrobia,2IUVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH1_k127_1909759_4	926551.KB900703_gene1072	9.18e-18	95.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1HYFM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
DTH1_k127_1909759_3	1395587.P364_0100735	1.68e-31	136.0	COG1409@1|root,COG1409@2|Bacteria,1V574@1239|Firmicutes,4HW52@91061|Bacilli,26S57@186822|Paenibacillaceae	91061|Bacilli	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH1_k127_1909759_1	481448.Minf_0292	2.058e-59	217.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,37G1D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
DTH1_k127_1909759_0	316067.Geob_0443	1.331e-76	268.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,43SZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
DTH1_k127_1910676_2	497964.CfE428DRAFT_4495	1.527e-110	366.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DTH1_k127_1910676_6	497964.CfE428DRAFT_4494	5.125e-18	93.0	2DS8G@1|root,33EZT@2|Bacteria,46T9M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DTH1_k127_1910676_4	497964.CfE428DRAFT_4493	1.721e-43	164.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
DTH1_k127_1910676_5	1403819.BATR01000049_gene1414	3.351e-27	116.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DTH1_k127_1910676_0	497964.CfE428DRAFT_4491	1.55e-251	783.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DTH1_k127_1910676_3	497964.CfE428DRAFT_4490	7.007e-92	310.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DTH1_k127_1910676_1	481448.Minf_2423	9.877e-209	656.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,37FV6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH1_k127_1929695_3	118168.MC7420_6062	5.75e-40	165.0	COG0438@1|root,COG0438@2|Bacteria,1G0EX@1117|Cyanobacteria,1H9C2@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH1_k127_1929695_4	452637.Oter_0284	9.11e-33	141.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
DTH1_k127_1929695_5	240016.ABIZ01000001_gene498	6.154e-14	82.0	2DKIU@1|root,309MI@2|Bacteria,46W7D@74201|Verrucomicrobia,2IUZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
DTH1_k127_1929695_1	497964.CfE428DRAFT_4614	6.474e-118	395.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
DTH1_k127_1929695_0	497964.CfE428DRAFT_4613	4.108e-145	466.0	COG0451@1|root,COG0451@2|Bacteria,46S80@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH1_k127_1929695_2	497964.CfE428DRAFT_4611	9.207e-48	179.0	COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DTH1_k127_193824_2	1379698.RBG1_1C00001G1874	5.157e-66	234.0	COG0351@1|root,COG0351@2|Bacteria,2NP3M@2323|unclassified Bacteria	2|Bacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00941,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI
DTH1_k127_193824_3	344747.PM8797T_07909	2.216e-14	85.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_193824_1	224911.27351242	4.129e-108	376.0	COG4191@1|root,COG4191@2|Bacteria,1NC2U@1224|Proteobacteria,2U484@28211|Alphaproteobacteria,3K3MC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MASE3,Response_reg
DTH1_k127_193824_0	478741.JAFS01000002_gene302	5.369e-175	566.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,37G1H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
DTH1_k127_1942633_0	234267.Acid_2264	1.448e-206	652.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
DTH1_k127_1942633_6	926551.KB900703_gene1072	4.82e-17	89.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1HYFM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
DTH1_k127_1942633_2	1499967.BAYZ01000026_gene1631	1.088e-128	434.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH1_k127_1942633_3	497964.CfE428DRAFT_0088	1.182e-53	199.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH1_k127_1942633_1	240016.ABIZ01000001_gene2673	1.204e-174	580.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
DTH1_k127_1942633_4	1396141.BATP01000035_gene4047	7.45e-51	192.0	COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
DTH1_k127_1942633_5	313606.M23134_05981	1.368e-29	128.0	COG4123@1|root,COG4123@2|Bacteria,4NKPF@976|Bacteroidetes,47SG7@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH1_k127_1944661_0	1254432.SCE1572_04430	1.105e-101	338.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,43C30@68525|delta/epsilon subdivisions,2X7DN@28221|Deltaproteobacteria,2YUXV@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
DTH1_k127_1944661_1	448385.sce0660	8.466e-80	286.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
DTH1_k127_1960376_0	1077285.AGDG01000045_gene2975	1.731e-266	847.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH1_k127_19651_2	497964.CfE428DRAFT_5370	1.444e-47	173.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
DTH1_k127_19651_0	234267.Acid_0830	7.279e-159	511.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DTH1_k127_19651_1	234267.Acid_0830	3.674e-73	254.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DTH1_k127_19651_3	865861.AZSU01000005_gene945	1.18e-27	116.0	COG1680@1|root,COG1680@2|Bacteria,1TRR5@1239|Firmicutes,249KP@186801|Clostridia,36H4V@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
DTH1_k127_1972186_2	1216932.CM240_0778	1.842e-05	55.0	COG2244@1|root,COG2244@2|Bacteria,1TQ51@1239|Firmicutes,24DRX@186801|Clostridia,36G90@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH1_k127_1972186_1	452637.Oter_3990	1.134e-138	449.0	COG0451@1|root,COG0451@2|Bacteria,46TXA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH1_k127_1972186_0	313624.NSP_23270	2.19e-176	558.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria,1HM8T@1161|Nostocales	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH1_k127_1980924_2	497964.CfE428DRAFT_3997	1.652e-62	226.0	COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RicinB_lectin_2
DTH1_k127_1980924_1	435832.HMPREF0604_01422	1.103e-67	239.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
DTH1_k127_1980924_0	861299.J421_5600	2.736e-94	320.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
DTH1_k127_1980924_3	861299.J421_5609	2.124e-62	219.0	COG1879@1|root,COG1879@2|Bacteria,1ZV3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
DTH1_k127_1997803_1	1121957.ATVL01000006_gene2545	6.165e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,4NMRH@976|Bacteroidetes,47QKT@768503|Cytophagia	976|Bacteroidetes	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
DTH1_k127_1997803_0	382464.ABSI01000005_gene1011	5.938e-162	526.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,2IVDM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
DTH1_k127_1997803_3	497964.CfE428DRAFT_6409	9.454e-11	68.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
DTH1_k127_1997803_2	497964.CfE428DRAFT_6409	4.312e-15	79.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
DTH1_k127_1999376_4	1122989.KB898579_gene1140	3.544e-41	158.0	COG3408@1|root,COG3408@2|Bacteria,4NESP@976|Bacteroidetes,2FMGH@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH1_k127_1999376_2	497964.CfE428DRAFT_6227	1.577e-67	240.0	COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
DTH1_k127_1999376_3	452637.Oter_4232	2.237e-53	192.0	2F7MR@1|root,34028@2|Bacteria,46VN7@74201|Verrucomicrobia,3K85B@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_1999376_0	452637.Oter_2033	1.086e-256	798.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
DTH1_k127_2009138_3	1242864.D187_003088	8.365e-77	273.0	COG2931@1|root,COG3055@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
DTH1_k127_2009138_2	452637.Oter_1332	1.251e-79	275.0	COG1075@1|root,COG1075@2|Bacteria,46VJF@74201|Verrucomicrobia,3K9J6@414999|Opitutae	414999|Opitutae	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2009138_4	1168289.AJKI01000040_gene3174	1.39e-72	277.0	2DYE6@1|root,349BE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2009138_5	497964.CfE428DRAFT_0242	7.321e-20	106.0	COG1858@1|root,COG3391@1|root,COG3534@1|root,COG5276@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,COG3534@2|Bacteria,COG5276@2|Bacteria,46U43@74201|Verrucomicrobia	74201|Verrucomicrobia	C	SMART LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,Laminin_G_3,PKD
DTH1_k127_2009138_0	278957.ABEA03000206_gene3779	1.814e-120	395.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
DTH1_k127_2009138_1	1121920.AUAU01000007_gene416	1.409e-94	316.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
DTH1_k127_2010633_3	1342301.JASD01000008_gene1718	5.244e-16	81.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,3ZV5Z@60136|Sulfitobacter	28211|Alphaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism	glnD	GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
DTH1_k127_2010633_1	497964.CfE428DRAFT_0262	1.285e-41	161.0	COG0688@1|root,COG0688@2|Bacteria,46VRI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DTH1_k127_2010633_0	497964.CfE428DRAFT_0263	2.226e-72	254.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DTH1_k127_2010633_4	1201288.M900_1405	9.831e-16	88.0	COG1280@1|root,COG1280@2|Bacteria,1N227@1224|Proteobacteria,43DA6@68525|delta/epsilon subdivisions,2WVZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
DTH1_k127_2010633_2	204669.Acid345_3346	3.269e-31	129.0	2E0G4@1|root,32W27@2|Bacteria	2|Bacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
DTH1_k127_2023913_5	886293.Sinac_6923	5.666e-43	158.0	COG2159@1|root,COG2159@2|Bacteria,2IZCY@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DTH1_k127_2023913_1	886293.Sinac_6924	1.003e-86	297.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DTH1_k127_2023913_4	697282.Mettu_1034	1.289e-44	168.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,1T0Q8@1236|Gammaproteobacteria,1XFBQ@135618|Methylococcales	135618|Methylococcales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
DTH1_k127_2023913_2	517418.Ctha_0234	8.128e-52	191.0	COG1225@1|root,COG1225@2|Bacteria,1FF4E@1090|Chlorobi	1090|Chlorobi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH1_k127_2023913_3	644282.Deba_0317	4.901e-45	173.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
DTH1_k127_2023913_0	452637.Oter_0819	0.0	1295.0	COG0574@1|root,COG0574@2|Bacteria,46XFR@74201|Verrucomicrobia,3K763@414999|Opitutae	414999|Opitutae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
DTH1_k127_2057772_5	269798.CHU_0938	5.364e-49	202.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
DTH1_k127_2057772_0	1173024.KI912153_gene216	0.0	1669.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH1_k127_2057772_2	1173024.KI912153_gene217	1.875e-153	490.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH1_k127_2057772_3	909663.KI867150_gene2007	2.578e-85	299.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DTH1_k127_2057772_1	765952.PUV_14580	6.589e-303	940.0	COG0365@1|root,COG0365@2|Bacteria,2JFRM@204428|Chlamydiae	204428|Chlamydiae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH1_k127_2057772_4	497964.CfE428DRAFT_0827	1.58e-72	250.0	COG2223@1|root,COG2223@2|Bacteria,46UH2@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_2061430_1	497964.CfE428DRAFT_0064	3.491e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
DTH1_k127_2061430_0	1229909.NSED_00255	1.166e-67	231.0	COG0432@1|root,arCOG04214@2157|Archaea,41T31@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH1_k127_2061430_2	640081.Dsui_2056	7.046e-18	90.0	COG1403@1|root,COG1403@2|Bacteria,1RIEZ@1224|Proteobacteria,2VTF6@28216|Betaproteobacteria,2KWR0@206389|Rhodocyclales	206389|Rhodocyclales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
DTH1_k127_2061430_3	1303518.CCALI_00913	7.607e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_2061430_4	103733.JNYO01000039_gene4416	3.874e-06	53.0	COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4E0PM@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulose Binding Domain Type IV	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	CBM_4_9,CBM_6,Glyco_hydro_43
DTH1_k127_208013_2	1396141.BATP01000046_gene1870	5.798e-91	309.0	COG4946@1|root,COG4946@2|Bacteria,46TXN@74201|Verrucomicrobia,2IV9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_208013_0	530564.Psta_2150	6.457e-114	383.0	COG1520@1|root,COG1520@2|Bacteria,2IYV0@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_208013_1	768671.ThimaDRAFT_4530	1.995e-91	306.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,1TKAD@1236|Gammaproteobacteria,1X15X@135613|Chromatiales	135613|Chromatiales	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_208013_3	240016.ABIZ01000001_gene398	3.288e-47	171.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
DTH1_k127_2082460_0	401053.AciPR4_2231	2.722e-164	560.0	COG3250@1|root,COG3250@2|Bacteria,3Y62S@57723|Acidobacteria,2JM9E@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH1_k127_2082460_1	1288963.ADIS_1157	1.975e-138	448.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2086967_2	452637.Oter_2161	1.769e-167	531.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
DTH1_k127_2086967_1	452637.Oter_2162	3.458e-172	544.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
DTH1_k127_2086967_0	1403819.BATR01000114_gene3945	6.208e-207	653.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia,2IU4V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
DTH1_k127_2097864_0	1379270.AUXF01000002_gene1201	4.854e-33	138.0	COG0204@1|root,COG0204@2|Bacteria,1ZUGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH1_k127_2097864_1	316067.Geob_3122	1.546e-22	111.0	COG0236@1|root,COG0236@2|Bacteria,1NE99@1224|Proteobacteria	1224|Proteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2097864_3	197221.22295598	7.785e-06	58.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH1_k127_2097864_2	929704.Myrod_3095	1.36e-17	93.0	2EEBB@1|root,3385N@2|Bacteria,4NV0N@976|Bacteroidetes,1I5RP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2108065_0	1123320.KB889712_gene8041	1.939e-52	211.0	COG1501@1|root,COG5492@1|root,COG1501@2|Bacteria,COG5492@2|Bacteria,2I4RN@201174|Actinobacteria	201174|Actinobacteria	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
DTH1_k127_2108065_1	203119.Cthe_1271	4.278e-06	60.0	COG2273@1|root,COG3507@1|root,COG4193@1|root,COG2273@2|Bacteria,COG3507@2|Bacteria,COG4193@2|Bacteria,1TR04@1239|Firmicutes,24ATC@186801|Clostridia,3WG7I@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	AbfB,Big_3,CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_43,RicinB_lectin_2
DTH1_k127_212662_0	1123508.JH636440_gene2840	4.777e-92	312.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_212662_4	635013.TherJR_2042	3.607e-25	112.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DTH1_k127_212662_3	497964.CfE428DRAFT_6522	5.808e-38	153.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
DTH1_k127_212662_1	497964.CfE428DRAFT_5454	3.737e-64	233.0	COG0122@1|root,COG0122@2|Bacteria,46SVK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	8-oxoguanine DNA glycosylase, N-terminal domain	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
DTH1_k127_212662_2	1396141.BATP01000057_gene2980	6.208e-56	201.0	COG0503@1|root,COG0503@2|Bacteria,46SV8@74201|Verrucomicrobia,2IUHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
DTH1_k127_212662_5	278957.ABEA03000020_gene1730	2.968e-23	101.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia,3K77A@414999|Opitutae	414999|Opitutae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH1_k127_2137585_2	1097668.BYI23_C006580	1.183e-35	144.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
DTH1_k127_2137585_1	344747.PM8797T_14579	3.447e-49	180.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_2137585_0	497964.CfE428DRAFT_1053	3.778e-156	501.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH1_k127_213961_0	497964.CfE428DRAFT_2672	3.69e-200	634.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH1_k127_213961_4	103733.JNYO01000007_gene5239	6.016e-05	57.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4E1H7@85010|Pseudonocardiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH1_k127_213961_2	1291050.JAGE01000002_gene3876	1.099e-26	129.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3WIWU@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
DTH1_k127_213961_1	926549.KI421517_gene3311	1.114e-40	175.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH1_k127_213961_3	530564.Psta_3017	3.303e-14	75.0	COG1053@1|root,COG1053@2|Bacteria,2IXHQ@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH1_k127_2140032_0	1123242.JH636434_gene4307	1.356e-105	351.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH1_k127_2140032_1	1191523.MROS_0856	9.244e-57	203.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
DTH1_k127_2140032_2	1283283.ATXA01000005_gene2190	6.493e-05	48.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESQP@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
DTH1_k127_2159396_0	452637.Oter_0138	1.499e-126	422.0	COG3934@1|root,COG3934@2|Bacteria,46YQT@74201|Verrucomicrobia,3KA0N@414999|Opitutae	414999|Opitutae	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2159396_1	497964.CfE428DRAFT_2588	4.707e-40	162.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH1_k127_2159396_2	497964.CfE428DRAFT_3386	1.117e-06	52.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
DTH1_k127_2162421_0	1121904.ARBP01000032_gene2006	2.349e-94	321.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,47RDC@768503|Cytophagia	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
DTH1_k127_2162421_1	1123073.KB899241_gene3101	6.865e-83	283.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1XCBQ@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH1_k127_2162421_3	391596.PBAL39_10776	2.852e-46	171.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,1ISZ2@117747|Sphingobacteriia	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
DTH1_k127_2162421_2	1408813.AYMG01000023_gene2064	4.894e-67	239.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IQDG@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH1_k127_217752_6	452637.Oter_2645	6.364e-33	130.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,3K83I@414999|Opitutae	414999|Opitutae	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
DTH1_k127_217752_4	1123489.AUAN01000002_gene1017	8.272e-40	158.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
DTH1_k127_217752_3	1396141.BATP01000058_gene1952	4.333e-44	172.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
DTH1_k127_217752_0	497964.CfE428DRAFT_2029	9.753e-101	338.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH1_k127_217752_5	1156937.MFUM_930026	9.993e-37	149.0	COG4137@1|root,COG4137@2|Bacteria,46T0T@74201|Verrucomicrobia,37GN8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DTH1_k127_217752_1	1396141.BATP01000057_gene2984	3.456e-85	295.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,2IU0T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Glutamyl-tRNAGlu reductase, N-terminal domain	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
DTH1_k127_217752_2	1337093.MBE-LCI_1964	6.491e-57	211.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,2P8HN@245186|Loktanella	28211|Alphaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
DTH1_k127_217752_7	1121434.AULY01000011_gene1739	3.162e-13	71.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MADW@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART Protein phosphatase	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
DTH1_k127_2183297_2	1254432.SCE1572_04435	4.048e-78	275.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
DTH1_k127_2183297_0	575540.Isop_0300	9.057e-134	437.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
DTH1_k127_2183297_1	1236514.BAKL01000065_gene4242	7.626e-113	376.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FM6F@200643|Bacteroidia,4AND4@815|Bacteroidaceae	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_2183297_3	497964.CfE428DRAFT_5022	8.849e-11	63.0	COG1136@1|root,COG1136@2|Bacteria,46SKR@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_218454_1	1449126.JQKL01000018_gene3257	2.58e-52	190.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,268GC@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
DTH1_k127_218454_0	1121930.AQXG01000003_gene2719	5.616e-103	347.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH1_k127_218454_2	709032.Sulku_1776	6.23e-36	151.0	COG0823@1|root,COG0823@2|Bacteria,1QXUF@1224|Proteobacteria,43234@68525|delta/epsilon subdivisions,2YTHN@29547|Epsilonproteobacteria	1224|Proteobacteria	U	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4214,DUF5122,HYR,VCBS
DTH1_k127_222345_4	1042163.BRLA_c034220	1.206e-17	89.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	-	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	DUF4332,HHH_5,Jacalin,Ribosomal_L4
DTH1_k127_222345_6	1089553.Tph_c21120	3.504e-05	55.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH1_k127_222345_5	1123508.JH636442_gene4113	1.774e-07	62.0	COG1413@1|root,COG1413@2|Bacteria,2J418@203682|Planctomycetes	203682|Planctomycetes	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH1_k127_222345_1	714943.Mucpa_7156	1.414e-99	343.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH1_k127_222345_3	649638.Trad_0164	2.748e-52	191.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_222345_0	1380391.JIAS01000012_gene4362	1.469e-109	375.0	COG3525@1|root,COG3525@2|Bacteria,1QR2G@1224|Proteobacteria,2UDYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	beta-N-acetylglucosaminidase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	NAGidase
DTH1_k127_222345_2	1254432.SCE1572_38245	1.624e-56	225.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
DTH1_k127_2235342_1	307480.IW16_23585	5.166e-28	132.0	COG5184@1|root,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,1IIHQ@117743|Flavobacteriia,3ZNMC@59732|Chryseobacterium	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
DTH1_k127_2235342_0	497964.CfE428DRAFT_5035	5.316e-80	268.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DTH1_k127_2240208_4	1242864.D187_001666	5.238e-28	119.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
DTH1_k127_2240208_1	1403819.BATR01000112_gene3876	4.557e-80	278.0	COG1082@1|root,COG1082@2|Bacteria,46T96@74201|Verrucomicrobia,2IUNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_2240208_3	240016.ABIZ01000001_gene3878	2.324e-33	140.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DTH1_k127_2240208_5	794903.OPIT5_29840	1.429e-23	107.0	2FBS3@1|root,307HF@2|Bacteria,46W7T@74201|Verrucomicrobia,3K85M@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2240208_2	530564.Psta_2414	8.649e-52	186.0	COG0346@1|root,COG0346@2|Bacteria,2J1AZ@203682|Planctomycetes	203682|Planctomycetes	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH1_k127_2240208_0	497964.CfE428DRAFT_3658	3.015e-155	501.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CBM_6,Glyco_hydro_16,Trypsin,VCBS
DTH1_k127_2258513_0	349966.DJ58_4193	3.184e-80	277.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,1SXIQ@1236|Gammaproteobacteria,41HAT@629|Yersinia	1236|Gammaproteobacteria	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
DTH1_k127_2258513_1	861299.J421_6031	1.207e-24	110.0	COG0517@1|root,COG0517@2|Bacteria,1ZV6T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH1_k127_226848_0	330214.NIDE3236	7.924e-177	564.0	COG1140@1|root,COG1140@2|Bacteria,3J1FU@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
DTH1_k127_226848_6	247490.KSU1_B0259	3.383e-24	116.0	COG3381@1|root,COG3381@2|Bacteria,2J3EZ@203682|Planctomycetes	203682|Planctomycetes	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
DTH1_k127_226848_5	237368.SCABRO_01075	6.967e-32	136.0	2AKTZ@1|root,31BM1@2|Bacteria,2J2UU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_226848_8	452637.Oter_3126	8.37e-20	93.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
DTH1_k127_226848_4	290397.Adeh_3087	7.198e-86	293.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
DTH1_k127_226848_2	1379698.RBG1_1C00001G0297	8.387e-124	409.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
DTH1_k127_226848_7	1121920.AUAU01000009_gene1858	5.66e-22	104.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH1_k127_226848_3	1125863.JAFN01000001_gene561	1.411e-109	364.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
DTH1_k127_226848_1	1396141.BATP01000019_gene1673	3.277e-127	426.0	COG5557@1|root,COG5557@2|Bacteria,46U15@74201|Verrucomicrobia,2ITS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
DTH1_k127_2269125_2	1009370.ALO_04341	2.191e-45	167.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H29G@909932|Negativicutes	909932|Negativicutes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DTH1_k127_2269125_0	1123070.KB899251_gene679	1.055e-192	620.0	COG0488@1|root,COG0488@2|Bacteria,46SJA@74201|Verrucomicrobia,2ITVQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH1_k127_2269125_1	768710.DesyoDRAFT_1775	4.325e-61	227.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
DTH1_k127_2276299_1	497964.CfE428DRAFT_0873	3.35e-91	306.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
DTH1_k127_2276299_2	1156937.MFUM_260026	1.941e-26	117.0	COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,37H9P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
DTH1_k127_2276299_0	497964.CfE428DRAFT_0194	2.063e-295	915.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
DTH1_k127_228403_0	497964.CfE428DRAFT_5737	1.409e-198	626.0	COG0673@1|root,COG0673@2|Bacteria,46UQI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_228403_4	449447.MAE_07890	2.125e-10	73.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G233@1117|Cyanobacteria	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14
DTH1_k127_228403_1	935948.KE386494_gene695	1.541e-145	486.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
DTH1_k127_228403_5	1273125.Rrhod_2956	0.0003437	49.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FUXM@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
DTH1_k127_228403_2	471223.GWCH70_1512	3.284e-21	100.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1WEX0@129337|Geobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
DTH1_k127_228403_3	1123248.KB893324_gene1755	3.451e-17	88.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH1_k127_2323899_2	373994.Riv7116_6589	9.812e-52	212.0	COG2755@1|root,COG2755@2|Bacteria,1GHUC@1117|Cyanobacteria,1HSHZ@1161|Nostocales	1117|Cyanobacteria	E	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_2323899_4	1122176.KB903570_gene4811	0.0007917	54.0	COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1J10W@117747|Sphingobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,SprB,TSP_3
DTH1_k127_2323899_1	1121920.AUAU01000009_gene1881	4.799e-56	226.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH1_k127_2323899_0	1353529.M899_0311	2.215e-124	404.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
DTH1_k127_2323899_3	864051.BurJ1DRAFT_0895	5.968e-07	56.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R1VH@1224|Proteobacteria,2WI5Y@28216|Betaproteobacteria,1KP12@119065|unclassified Burkholderiales	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,RCC1,RCC1_2,SLH,WD40
DTH1_k127_2339501_4	575540.Isop_3679	3.521e-101	341.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
DTH1_k127_2339501_2	1123242.JH636434_gene5489	1.518e-139	458.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
DTH1_k127_2339501_12	1297865.APJD01000005_gene3689	8.097e-07	60.0	2BPPV@1|root,32IH2@2|Bacteria,1NFYU@1224|Proteobacteria,2UIKJ@28211|Alphaproteobacteria,3K4IG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2339501_9	383372.Rcas_1314	5.438e-20	91.0	2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2339501_6	1499967.BAYZ01000119_gene3173	5.651e-53	194.0	28JE3@1|root,2Z98B@2|Bacteria,2NQ8M@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
DTH1_k127_2339501_0	497964.CfE428DRAFT_3901	1.155e-229	729.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH1_k127_2339501_1	1396141.BATP01000032_gene4274	4.051e-215	687.0	COG1073@1|root,COG1073@2|Bacteria,46Z70@74201|Verrucomicrobia,2IWQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH1_k127_2339501_7	261292.Nit79A3_1788	9.597e-33	148.0	28HU5@1|root,2Z80X@2|Bacteria,1R55N@1224|Proteobacteria,2VI32@28216|Betaproteobacteria,372Y4@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM TIGR03790 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2339501_11	113355.CM001775_gene3666	1.203e-13	83.0	COG1404@1|root,COG1404@2|Bacteria,1G1G8@1117|Cyanobacteria	1117|Cyanobacteria	O	Subtilisin-like serine protease	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH1_k127_2339501_5	765420.OSCT_3130	2.06e-67	245.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
DTH1_k127_2339501_8	313628.LNTAR_18430	2.138e-28	120.0	COG1372@1|root,COG1372@2|Bacteria	2|Bacteria	L	intein-mediated protein splicing	-	-	1.1.98.6,3.6.3.14,3.6.3.15,4.1.1.35	ko:K02117,ko:K08678,ko:K21636	ko00190,ko00230,ko00240,ko00520,ko01100,map00190,map00230,map00240,map00520,map01100	M00053,M00159,M00361	R01384,R11633,R11634,R11635,R11636	RC00508,RC00613	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-cone,DUF4280,Intein_splicing,LAGLIDADG_3,NRDD,PT-HINT
DTH1_k127_2339501_3	1123242.JH636434_gene4307	9.388e-108	357.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH1_k127_2343962_0	1303518.CCALI_00634	2.246e-305	959.0	28K2K@1|root,2Z9RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2349111_2	945713.IALB_1296	3.824e-23	113.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Y_Y_Y
DTH1_k127_2349111_1	1089550.ATTH01000001_gene181	7.483e-31	130.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1FJDT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
DTH1_k127_2349111_3	316274.Haur_4882	1.921e-12	79.0	2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi,375HC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LIM, zinc-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DA1-like
DTH1_k127_2349111_0	330214.NIDE2536	1.114e-217	691.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
DTH1_k127_2383363_1	1396141.BATP01000060_gene4765	7.724e-29	133.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
DTH1_k127_2383363_0	497964.CfE428DRAFT_2630	2.939e-80	271.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2386013_3	2903.EOD40718	8.03e-36	143.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
DTH1_k127_2386013_1	1123070.KB899248_gene161	1.214e-43	167.0	COG0283@1|root,COG0283@2|Bacteria,46VD5@74201|Verrucomicrobia,2IUAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Cytidylate kinase	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
DTH1_k127_2386013_2	1396418.BATQ01000073_gene500	2.098e-40	157.0	COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,2IUG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH1_k127_2386013_0	925409.KI911562_gene2080	7.191e-148	482.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1IX0E@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_2386013_5	497964.CfE428DRAFT_4596	6.776e-21	109.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283,ko:K02454,ko:K03220,ko:K03466	ko03070,ko05111,map03070,map05111	M00331,M00332	-	-	ko00000,ko00001,ko00002,ko02035,ko02044,ko03036	3.A.12,3.A.15,3.A.6.1	-	-	Cytochrom_c3_2,FHA,FtsK_SpoIIIE,Response_reg,T2SSE,Yop-YscD_cpl,Yop-YscD_ppl
DTH1_k127_2386013_4	497964.CfE428DRAFT_5353	4.654e-23	116.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH1_k127_2386013_6	497964.CfE428DRAFT_4993	9.321e-16	82.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2390429_1	1463936.JOJI01000044_gene7868	5.864e-40	160.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DTH1_k127_2390429_0	1123508.JH636439_gene1348	7.819e-101	355.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG3794@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3794@2|Bacteria,2IX6X@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
DTH1_k127_2394253_0	1045855.DSC_09435	1.746e-25	107.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1X7HF@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH1_k127_2394253_1	1303518.CCALI_02493	3.22e-18	94.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_2394253_2	886293.Sinac_1857	1.407e-13	81.0	COG2165@1|root,COG2165@2|Bacteria,2IYXI@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_239913_0	760568.Desku_0794	1.568e-39	157.0	COG3547@1|root,COG3547@2|Bacteria,1V0B6@1239|Firmicutes,248VY@186801|Clostridia,264BH@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase, IS111A IS1328 IS1533	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
DTH1_k127_239913_2	208444.JNYY01000009_gene3473	6.745e-18	89.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4E1BS@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
DTH1_k127_239913_1	443152.MDG893_11576	1.536e-18	94.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4643S@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH1_k127_242076_0	1227360.C176_13277	2.968e-53	210.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,26EP7@186818|Planococcaceae	91061|Bacilli	S	Penicillin acylase	acyII	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DTH1_k127_2424101_0	1380394.JADL01000003_gene4962	1.478e-175	576.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
DTH1_k127_2424101_5	497964.CfE428DRAFT_3384	3.213e-138	442.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DTH1_k127_2424101_4	886293.Sinac_4629	1.496e-142	468.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_2424101_1	1123242.JH636434_gene4648	2.944e-175	562.0	COG0673@1|root,COG0673@2|Bacteria,2IXDR@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_2424101_3	1303518.CCALI_00393	8.106e-152	496.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DUF1080,DUF4241
DTH1_k127_2424101_2	497964.CfE428DRAFT_5395	3.469e-160	514.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH1_k127_2424101_9	1396418.BATQ01000003_gene1334	1.235e-11	75.0	COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia,2IUR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH1_k127_2424101_6	481448.Minf_0919	5.412e-40	156.0	COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia,37GG9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH1_k127_2424101_10	382464.ABSI01000010_gene3336	1.885e-09	69.0	COG3064@1|root,COG3064@2|Bacteria,46VZ5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2424101_7	456442.Mboo_0115	2.612e-22	110.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
DTH1_k127_2424101_8	215803.DB30_6944	4.363e-13	70.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2X2JP@28221|Deltaproteobacteria,2YY11@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
DTH1_k127_2450715_1	1267535.KB906767_gene3867	1.543e-21	100.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N
DTH1_k127_2450715_2	1303518.CCALI_00602	1.196e-14	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_2450715_0	344747.PM8797T_26405	5.519e-104	354.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_2450715_3	575540.Isop_0126	6.514e-14	83.0	COG2165@1|root,COG2165@2|Bacteria,2J1UJ@203682|Planctomycetes	2|Bacteria	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_2465668_7	402777.KB235904_gene4520	1.724e-13	81.0	COG2931@1|root,COG3266@1|root,COG3391@1|root,COG4257@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria,COG4257@2|Bacteria,1GCE0@1117|Cyanobacteria,1HEJN@1150|Oscillatoriales	1117|Cyanobacteria	QV	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,DUF5122,HemolysinCabind
DTH1_k127_2465668_2	449447.MAE_29050	3.369e-53	199.0	COG1621@1|root,COG2931@1|root,COG1621@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
DTH1_k127_2465668_3	1123399.AQVE01000001_gene684	3.635e-48	184.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
DTH1_k127_2465668_0	1380394.JADL01000003_gene4962	9.019e-214	691.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
DTH1_k127_2465668_1	497964.CfE428DRAFT_2511	1.1e-67	235.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
DTH1_k127_2465668_5	398767.Glov_1965	3.713e-23	109.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,42ZGY@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH1_k127_2465668_6	401526.TcarDRAFT_1486	4.406e-23	111.0	COG1127@1|root,COG1127@2|Bacteria,1UGV0@1239|Firmicutes,4H251@909932|Negativicutes	909932|Negativicutes	Q	ABC transporter, ATP-binding protein	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH1_k127_2465668_8	243231.GSU1899	1.259e-05	57.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43UDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH1_k127_2465668_9	1121468.AUBR01000018_gene2682	0.0001166	53.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH1_k127_2465668_4	1280390.CBQR020000006_gene132	1.406e-26	120.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,26RNV@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	addA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DTH1_k127_2470643_0	118173.KB235914_gene2616	2.983e-137	462.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
DTH1_k127_2470643_1	314345.SPV1_01182	3.971e-43	168.0	28N94@1|root,2ZBD8@2|Bacteria,1MWA4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2471188_0	1382359.JIAL01000001_gene1319	1.79e-63	221.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnC	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
DTH1_k127_2471188_2	1123508.JH636441_gene3117	3.377e-33	138.0	COG1413@1|root,COG1413@2|Bacteria,2J2VX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_2471188_3	458817.Shal_3325	4.753e-05	55.0	COG4932@1|root,COG4932@2|Bacteria,1R94W@1224|Proteobacteria,1RSPU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2471188_1	1499967.BAYZ01000147_gene711	7.823e-41	163.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_2491803_1	1169161.KB897722_gene4484	2.438e-11	78.0	COG3250@1|root,COG3250@2|Bacteria,2I3FI@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
DTH1_k127_2491803_0	1123248.KB893318_gene4130	5.902e-255	812.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IUSY@117747|Sphingobacteriia	976|Bacteroidetes	G	family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
DTH1_k127_2491803_2	305700.B447_09528	4.587e-05	46.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,2KVKA@206389|Rhodocyclales	206389|Rhodocyclales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
DTH1_k127_2541523_1	1500301.JQMF01000013_gene4490	8.298e-19	85.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,4BDVM@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
DTH1_k127_2541523_0	335543.Sfum_1471	3.373e-311	968.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,2MQ9F@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
DTH1_k127_2541523_2	99598.Cal7507_2587	6.89e-09	61.0	COG0385@1|root,COG0385@2|Bacteria,1GJMF@1117|Cyanobacteria,1HMZI@1161|Nostocales	1117|Cyanobacteria	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
DTH1_k127_2552818_0	1453501.JELR01000001_gene2132	9.857e-75	267.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,1RR8K@1236|Gammaproteobacteria,466XF@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH1_k127_2557679_1	497964.CfE428DRAFT_4695	1.585e-105	353.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DTH1_k127_2557679_0	317936.Nos7107_4863	4.473e-177	568.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
DTH1_k127_256151_3	794903.OPIT5_12085	7.251e-36	137.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46UZR@74201|Verrucomicrobia,3K795@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
DTH1_k127_256151_0	309807.SRU_0678	1.773e-105	355.0	COG3829@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
DTH1_k127_256151_1	452637.Oter_1551	1.637e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,46SRM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_256151_2	313628.LNTAR_08349	1.905e-54	203.0	COG0472@1|root,COG0472@2|Bacteria	313628.LNTAR_08349|-	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_256151_4	530564.Psta_4220	7.359e-24	104.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH1_k127_2562555_2	497964.CfE428DRAFT_1374	4.793e-17	93.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
DTH1_k127_2562555_0	653733.Selin_0475	3.618e-144	465.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
DTH1_k127_2562555_1	234267.Acid_1623	8.753e-94	315.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
DTH1_k127_2565036_1	1287276.X752_02890	1.173e-87	302.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2UQQC@28211|Alphaproteobacteria,43N9M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
DTH1_k127_2565036_2	530564.Psta_3458	2.213e-69	250.0	COG1416@1|root,COG4798@1|root,COG1416@2|Bacteria,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
DTH1_k127_2565036_0	1396141.BATP01000040_gene2167	0.0	1260.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH1_k127_2565065_0	452637.Oter_3509	4.539e-89	311.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_257595_7	497964.CfE428DRAFT_0970	3.068e-12	68.0	COG0457@1|root,COG0457@2|Bacteria,46UPB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_8
DTH1_k127_257595_3	671143.DAMO_1689	2.969e-31	131.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
DTH1_k127_257595_0	671143.DAMO_1688	8.684e-80	285.0	COG3278@1|root,COG3278@2|Bacteria,2NRHY@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_257595_4	1051632.TPY_0746	4.737e-30	125.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,24VD9@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH1_k127_257595_5	278957.ABEA03000176_gene2840	5.885e-25	107.0	COG4309@1|root,COG4309@2|Bacteria,46XTU@74201|Verrucomicrobia,3K814@414999|Opitutae	414999|Opitutae	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
DTH1_k127_257595_2	392500.Swoo_0456	9.391e-44	173.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,1RQJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH1_k127_257595_6	497964.CfE428DRAFT_4993	2.252e-12	80.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_257595_1	406124.ACPC01000017_gene625	6.091e-69	257.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
DTH1_k127_2579367_0	1121405.dsmv_1085	5.272e-123	415.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
DTH1_k127_2579367_1	1396418.BATQ01000106_gene5306	9.285e-43	173.0	2DTXG@1|root,33N3G@2|Bacteria,46WXU@74201|Verrucomicrobia,2IVTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH1_k127_2589864_1	1056820.KB900635_gene967	7.953e-30	123.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,2PN6F@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Sodium:solute symporter family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH1_k127_2589864_0	264732.Moth_1872	1.112e-121	436.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
DTH1_k127_2592321_0	497964.CfE428DRAFT_3562	3.899e-129	424.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DTH1_k127_2592321_1	1209989.TepiRe1_1813	1.052e-110	367.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,42EMP@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ketose-bisphosphate aldolase, class-II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
DTH1_k127_2592321_2	497964.CfE428DRAFT_3685	4.416e-45	168.0	COG0071@1|root,COG0071@2|Bacteria,46T3G@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the small heat shock protein (HSP20) family	ibpA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH1_k127_2592321_4	497964.CfE428DRAFT_3684	4.488e-30	124.0	COG0071@1|root,COG0071@2|Bacteria,46WRX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
DTH1_k127_2592321_5	1210884.HG799466_gene12517	9.608e-12	75.0	COG4968@1|root,COG4968@2|Bacteria,2J4X1@203682|Planctomycetes	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_2601385_2	909663.KI867150_gene2890	9.637e-45	174.0	COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,42PA3@68525|delta/epsilon subdivisions,2WM6X@28221|Deltaproteobacteria,2MQSC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
DTH1_k127_2601385_3	247490.KSU1_C1448	6.357e-31	130.0	2CA7I@1|root,30E5G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2601385_1	1088869.GMO_02930	1.03e-49	189.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria	1224|Proteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
DTH1_k127_2601385_4	1336233.JAEH01000025_gene1035	4.658e-08	63.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,2Q9HF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
DTH1_k127_2601385_0	870187.Thini_1169	7.806e-72	252.0	COG0589@1|root,COG0589@2|Bacteria,1N5Z8@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH1_k127_2614068_0	1396141.BATP01000003_gene5036	3.229e-263	854.0	COG2931@1|root,COG3299@1|root,COG4733@1|root,COG5267@1|root,COG2931@2|Bacteria,COG3299@2|Bacteria,COG4733@2|Bacteria,COG5267@2|Bacteria,46TXW@74201|Verrucomicrobia,2IWPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH1_k127_2614068_1	497964.CfE428DRAFT_5081	3.971e-150	489.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_2614068_4	497964.CfE428DRAFT_5080	3.794e-26	116.0	29N11@1|root,344HT@2|Bacteria,46WBB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2614068_7	452637.Oter_2961	1.939e-15	79.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	e_coli_core.b2415,iAF1260.b2415,iB21_1397.B21_02276,iBWG_1329.BWG_2177,iE2348C_1286.E2348C_2601,iEC042_1314.EC042_2624,iEC55989_1330.EC55989_2705,iECABU_c1320.ECABU_c27360,iECBD_1354.ECBD_1266,iECB_1328.ECB_02315,iECDH10B_1368.ECDH10B_2580,iECDH1ME8569_1439.ECDH1ME8569_2349,iECDH1ME8569_1439.EcDH1_1246,iECD_1391.ECD_02315,iECED1_1282.ECED1_2859,iECH74115_1262.ECH74115_3646,iECIAI1_1343.ECIAI1_2473,iECIAI39_1322.ECIAI39_2561,iECNA114_1301.ECNA114_2492,iECO103_1326.ECO103_2934,iECO111_1330.ECO111_3145,iECO26_1355.ECO26_3468,iECOK1_1307.ECOK1_2732,iECP_1309.ECP_2439,iECS88_1305.ECS88_2605,iECSE_1348.ECSE_2706,iECSF_1327.ECSF_2279,iECSP_1301.ECSP_3363,iECUMN_1333.ECUMN_2737,iECW_1372.ECW_m2644,iECs_1301.ECs3287,iEKO11_1354.EKO11_1313,iETEC_1333.ETEC_2528,iEcDH1_1363.EcDH1_1246,iEcE24377_1341.EcE24377A_2702,iEcHS_1320.EcHS_A2550,iEcSMS35_1347.EcSMS35_2570,iEcolC_1368.EcolC_1263,iG2583_1286.G2583_2947,iJO1366.b2415,iJR904.b2415,iLF82_1304.LF82_1769,iNRG857_1313.NRG857_12110,iPC815.YPO2993,iSBO_1134.SBO_2439,iSDY_1059.SDY_2612,iSFV_1184.SFV_2467,iSF_1195.SF2470,iSFxv_1172.SFxv_2719,iSSON_1240.SSON_2504,iS_1188.S2616,iSbBS512_1146.SbBS512_E2765,iUMN146_1321.UM146_04545,iUMNK88_1353.UMNK88_3017,iUTI89_1310.UTI89_C2749,iWFL_1372.ECW_m2644,iY75_1357.Y75_RS12655,iZ_1308.Z3681,ic_1306.c2950	PTS-HPr
DTH1_k127_2614068_5	331678.Cphamn1_0275	3.417e-20	98.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DTH1_k127_2614068_2	1122927.KB895429_gene355	3.188e-80	275.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH1_k127_2614068_8	497964.CfE428DRAFT_5371	5.286e-05	53.0	COG4121@1|root,COG4121@2|Bacteria	2|Bacteria	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151	ko:K00773,ko:K07319,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110	-	R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko02048,ko03016	-	-	-	DAO,Methyltransf_30
DTH1_k127_2614068_3	1403819.BATR01000167_gene5697	5.512e-30	128.0	COG2453@1|root,COG2453@2|Bacteria,46XSU@74201|Verrucomicrobia,2IWHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Protein-tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
DTH1_k127_2614068_6	478741.JAFS01000002_gene94	1.399e-18	92.0	COG0792@1|root,COG0792@2|Bacteria,46ZGA@74201|Verrucomicrobia,37H17@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DTH1_k127_2618218_0	886293.Sinac_0918	1.062e-172	557.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
DTH1_k127_2618218_1	497964.CfE428DRAFT_4863	3.793e-110	380.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2618218_2	497964.CfE428DRAFT_4864	2.56e-78	268.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2619851_4	497964.CfE428DRAFT_4177	9.037e-26	107.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH1_k127_2619851_5	1123256.KB907940_gene188	5.338e-23	105.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
DTH1_k127_2619851_2	1240350.AMZE01000024_gene1610	2.442e-98	337.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
DTH1_k127_2619851_1	1116369.KB890025_gene5283	4.816e-113	379.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,43GYK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
DTH1_k127_2619851_0	635013.TherJR_0057	1.442e-156	509.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
DTH1_k127_2619851_3	1380394.JADL01000001_gene2442	2.059e-57	216.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH1_k127_2622070_6	1232410.KI421424_gene1819	9.76e-08	57.0	2E9MH@1|root,333U5@2|Bacteria,1NDRZ@1224|Proteobacteria,42VYW@68525|delta/epsilon subdivisions,2WR91@28221|Deltaproteobacteria,43VTK@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2622070_2	1121403.AUCV01000020_gene3110	6.563e-120	395.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
DTH1_k127_2622070_1	1340493.JNIF01000003_gene3969	3.533e-175	561.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_2622070_0	452637.Oter_4336	7.164e-316	981.0	COG3534@1|root,COG3534@2|Bacteria,46UU3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
DTH1_k127_2622070_5	1117319.PSPO_04042	3.296e-08	64.0	2BCPH@1|root,3269T@2|Bacteria,1RJN1@1224|Proteobacteria,1S744@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4824)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4824
DTH1_k127_2622070_3	338963.Pcar_1339	2.065e-69	249.0	28IWG@1|root,2Z8US@2|Bacteria,1NHDW@1224|Proteobacteria,42MHT@68525|delta/epsilon subdivisions,2WMMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
DTH1_k127_2622070_4	1337936.IJ00_11875	1.768e-17	88.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1GQ7T@1117|Cyanobacteria,1HJ6I@1161|Nostocales	1117|Cyanobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
DTH1_k127_2635226_1	1168034.FH5T_19355	1.37e-33	141.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_2635226_2	1123242.JH636435_gene1168	1.138e-25	114.0	COG1413@1|root,COG1413@2|Bacteria,2J2I0@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_2635226_0	547042.BACCOPRO_00992	7.988e-122	419.0	COG1572@1|root,COG1572@2|Bacteria,4PJMZ@976|Bacteroidetes,2FZ9J@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
DTH1_k127_2639464_0	1403819.BATR01000031_gene981	4.276e-107	361.0	COG1793@1|root,COG1793@2|Bacteria,46TK9@74201|Verrucomicrobia,2IV60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_2639464_1	382464.ABSI01000014_gene1462	8.887e-35	140.0	COG3934@1|root,COG3934@2|Bacteria,46Z5X@74201|Verrucomicrobia,2IWQJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2648275_0	452637.Oter_0818	4.602e-252	785.0	COG0334@1|root,COG0334@2|Bacteria,46UBX@74201|Verrucomicrobia,3K7SK@414999|Opitutae	414999|Opitutae	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH1_k127_2648275_1	452637.Oter_0819	7.185e-63	224.0	COG0574@1|root,COG0574@2|Bacteria,46XFR@74201|Verrucomicrobia,3K763@414999|Opitutae	414999|Opitutae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
DTH1_k127_2652121_0	497964.CfE428DRAFT_1406	6.78e-53	199.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM CBS domain containing protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
DTH1_k127_2659787_1	1168289.AJKI01000021_gene1764	1.853e-86	303.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,2FPX5@200643|Bacteroidia,3XJSQ@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2
DTH1_k127_2659787_0	1123508.JH636439_gene600	1.417e-210	704.0	COG2755@1|root,COG5306@1|root,COG2755@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
DTH1_k127_2659787_2	435591.BDI_2049	1.092e-05	60.0	COG4733@1|root,COG4733@2|Bacteria,4PMY2@976|Bacteroidetes,2G0KB@200643|Bacteroidia	976|Bacteroidetes	S	Putative carbohydrate metabolism domain	-	-	-	-	-	-	-	-	-	-	-	-	PCMD
DTH1_k127_2664480_1	1267535.KB906767_gene3736	8.033e-103	338.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH1_k127_2664480_2	1307759.JOMJ01000004_gene2828	6.628e-56	205.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
DTH1_k127_2664480_0	335543.Sfum_1859	5.551e-213	685.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,42Q50@68525|delta/epsilon subdivisions,2WJN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2669565_0	1123508.JH636441_gene3756	5.279e-126	420.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_2672687_2	481448.Minf_1718	4.146e-91	326.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,37G03@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
DTH1_k127_2672687_3	452637.Oter_0292	4.094e-85	296.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
DTH1_k127_2672687_0	497964.CfE428DRAFT_3932	9.255e-201	644.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
DTH1_k127_2672687_7	497964.CfE428DRAFT_0896	4.642e-43	164.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_2672687_5	497964.CfE428DRAFT_1467	6.739e-63	222.0	COG0131@1|root,COG0131@2|Bacteria,46SR2@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
DTH1_k127_2672687_8	1265505.ATUG01000003_gene184	4.682e-12	76.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
DTH1_k127_2672687_4	886293.Sinac_6555	1.067e-67	238.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_2672687_1	1442599.JAAN01000005_gene1008	9.581e-150	480.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X46C@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH1_k127_2672687_6	595460.RRSWK_05819	1.576e-55	197.0	COG0677@1|root,COG0677@2|Bacteria,2IXVX@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH1_k127_2680406_2	1192034.CAP_7227	3.859e-38	153.0	COG1434@1|root,COG1434@2|Bacteria,1NDJM@1224|Proteobacteria,42XJW@68525|delta/epsilon subdivisions,2WSJ3@28221|Deltaproteobacteria,2YVV6@29|Myxococcales	28221|Deltaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH1_k127_2680406_1	360910.BAV2339	2.377e-76	271.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,3T1SB@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH1_k127_2680406_3	234267.Acid_3197	1.942e-08	56.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
DTH1_k127_2680406_0	714943.Mucpa_5012	2.722e-111	373.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IQDG@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH1_k127_2704486_3	452637.Oter_0799	2.3e-12	71.0	2910Q@1|root,2ZNNC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2704486_0	1395513.P343_05500	3.917e-50	185.0	COG1704@1|root,COG1704@2|Bacteria,1V3R9@1239|Firmicutes,4IR1H@91061|Bacilli,26PKG@186821|Sporolactobacillaceae	91061|Bacilli	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH1_k127_2704486_2	479435.Kfla_6730	4.619e-30	129.0	2CPKI@1|root,32SJC@2|Bacteria,2IQPS@201174|Actinobacteria,4DS6U@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
DTH1_k127_2704486_1	382464.ABSI01000010_gene3387	2.225e-48	182.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,2IU67@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH1_k127_2709383_0	794903.OPIT5_28445	2.508e-139	447.0	COG0677@1|root,COG0677@2|Bacteria	2|Bacteria	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	wbpA	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH1_k127_2709383_1	497964.CfE428DRAFT_1446	3.093e-125	434.0	COG2133@1|root,COG2133@2|Bacteria,46UME@74201|Verrucomicrobia	74201|Verrucomicrobia	G	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH1_k127_2709383_2	661478.OP10G_4722	7.195e-10	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_2713778_1	313612.L8106_04821	1.245e-91	321.0	2DNIH@1|root,32XPH@2|Bacteria,1G8A7@1117|Cyanobacteria,1HCDF@1150|Oscillatoriales	1117|Cyanobacteria	S	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
DTH1_k127_2713778_0	344747.PM8797T_00654	7.535e-146	479.0	COG2072@1|root,COG2072@2|Bacteria,2IZUB@203682|Planctomycetes	203682|Planctomycetes	P	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH1_k127_2713778_2	1107311.Q767_01615	7.63e-73	268.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
DTH1_k127_2713778_3	1267535.KB906767_gene1376	9.747e-12	68.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH1_k127_271935_0	391612.CY0110_28434	4.434e-123	401.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria,3KGGQ@43988|Cyanothece	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
DTH1_k127_271935_1	1267535.KB906767_gene4768	1.496e-80	276.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2725799_0	497964.CfE428DRAFT_3450	5.909e-56	205.0	COG2096@1|root,COG2096@2|Bacteria,46T1G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
DTH1_k127_2725799_1	497964.CfE428DRAFT_5078	9.285e-22	106.0	COG2133@1|root,COG2133@2|Bacteria,46V55@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH1_k127_2746614_2	1492737.FEM08_16420	6.176e-154	510.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
DTH1_k127_2746614_0	452637.Oter_1883	3.575e-311	972.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_2746614_1	452637.Oter_1829	1.117e-175	578.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_2746614_3	452637.Oter_1829	5.625e-129	434.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_2765694_5	234267.Acid_5634	5.53e-31	136.0	COG0823@1|root,COG4447@1|root,COG0823@2|Bacteria,COG4447@2|Bacteria,3Y9AF@57723|Acidobacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Peptidase_S8,SBBP
DTH1_k127_2765694_8	497964.CfE428DRAFT_4704	1.635e-14	82.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM outer membrane chaperone Skp (OmpH)	hlpA	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH1_k127_2765694_0	497964.CfE428DRAFT_6478	2.845e-188	596.0	COG1453@1|root,COG1453@2|Bacteria,46S6J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
DTH1_k127_2765694_6	497964.CfE428DRAFT_6673	8.788e-27	112.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH1_k127_2765694_2	1288963.ADIS_2835	2.45e-131	436.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH1_k127_2765694_1	478741.JAFS01000001_gene1976	1.795e-146	473.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
DTH1_k127_2765694_4	794903.OPIT5_06500	5.491e-32	141.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
DTH1_k127_2765694_3	1163617.SCD_n02152	1.44e-104	346.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
DTH1_k127_2773621_4	316274.Haur_3849	8.431e-21	97.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH1_k127_2773621_0	1403819.BATR01000093_gene2891	6.062e-233	735.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DTH1_k127_2773621_3	1038869.AXAN01000002_gene225	4.06e-30	132.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,2VIKI@28216|Betaproteobacteria,1K0I9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH1_k127_2773621_2	1125863.JAFN01000001_gene1724	1.516e-63	228.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
DTH1_k127_2773621_1	497964.CfE428DRAFT_1506	1.42e-147	478.0	COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
DTH1_k127_2782264_0	497964.CfE428DRAFT_1213	7.016e-105	351.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	DUF4388,HATPase_c,HTH_8,HisKA,Response_reg,SSF,Sigma54_activat
DTH1_k127_2791937_1	1235803.C825_03112	1.455e-40	163.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,2FN7Y@200643|Bacteroidia,22XPZ@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH1_k127_2791937_0	931627.MycrhDRAFT_5452	5.539e-55	199.0	COG1793@1|root,COG1793@2|Bacteria	2|Bacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,WGR
DTH1_k127_2793719_2	716544.wcw_0442	1.246e-16	83.0	COG1028@1|root,COG1028@2|Bacteria,2JG7F@204428|Chlamydiae	204428|Chlamydiae	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
DTH1_k127_2793719_0	497964.CfE428DRAFT_5990	1.136e-60	218.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_2793719_5	1387312.BAUS01000002_gene286	3.742e-05	53.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
DTH1_k127_2793719_4	948106.AWZT01000019_gene3975	3.641e-08	59.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2VXXB@28216|Betaproteobacteria,1K9C3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
DTH1_k127_2793719_1	880070.Cycma_1815	1.218e-52	192.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,AhpC-TSA_2
DTH1_k127_2793719_3	497964.CfE428DRAFT_6357	3.092e-10	62.0	COG3176@1|root,COG3176@2|Bacteria,46UGN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
DTH1_k127_2798361_1	1379270.AUXF01000004_gene3002	9.855e-108	365.0	COG2986@1|root,COG2986@2|Bacteria,1ZTEG@142182|Gemmatimonadetes	2|Bacteria	E	Aromatic amino acid lyase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009698,GO:0009699,GO:0009987,GO:0016043,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052883,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH1_k127_2798361_0	153721.MYP_192	6.115e-127	419.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DTH1_k127_2798361_2	485918.Cpin_1862	1.855e-73	256.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IUWM@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
DTH1_k127_2799122_0	497964.CfE428DRAFT_2425	8.015e-221	711.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U71@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Laminin_G_3
DTH1_k127_2799122_1	595460.RRSWK_04420	2.242e-119	400.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
DTH1_k127_2806425_2	323848.Nmul_A2162	1.264e-45	169.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
DTH1_k127_2806425_1	530564.Psta_1651	1.414e-76	271.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Peptidase_S9
DTH1_k127_2806425_3	861299.J421_1306	2.524e-12	70.0	COG0296@1|root,COG0296@2|Bacteria,1ZU2E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
DTH1_k127_2812103_5	1396418.BATQ01000058_gene90	2.599e-50	181.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DTH1_k127_2812103_0	234267.Acid_2416	1.196e-165	534.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
DTH1_k127_2812103_7	1303518.CCALI_02658	1.777e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_2812103_3	1123242.JH636435_gene1120	8.245e-97	327.0	COG1506@1|root,COG1506@2|Bacteria,2J1ST@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
DTH1_k127_2812103_2	215803.DB30_0528	1.287e-101	343.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2812103_4	382464.ABSI01000011_gene3037	1.384e-77	262.0	COG3837@1|root,COG3837@2|Bacteria,46T0V@74201|Verrucomicrobia,2IU8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH1_k127_2812103_8	1304874.JAFY01000001_gene2557	1.631e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,3TC3U@508458|Synergistetes	508458|Synergistetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
DTH1_k127_2812103_6	1380394.JADL01000003_gene4839	4.909e-23	104.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,2JTM5@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
DTH1_k127_2812103_1	794903.OPIT5_07185	4.355e-130	435.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,46V2T@74201|Verrucomicrobia,3K9RQ@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
DTH1_k127_2818284_7	497964.CfE428DRAFT_3481	2.625e-22	104.0	COG0443@1|root,COG0443@2|Bacteria,46TYN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
DTH1_k127_2818284_2	452637.Oter_0619	6.526e-68	239.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	VVA1313	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH1_k127_2818284_4	481448.Minf_1524	2.122e-34	141.0	COG0452@1|root,COG0452@2|Bacteria,46WUX@74201|Verrucomicrobia,37GRH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	DNA / pantothenate metabolism flavoprotein	-	-	6.3.2.5	ko:K21977	ko00770,map00770	M00120	R04231	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP
DTH1_k127_2818284_0	278957.ABEA03000085_gene2554	1.052e-108	359.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
DTH1_k127_2818284_3	335543.Sfum_2639	2.015e-59	227.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MQVW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DTH1_k127_2818284_5	880073.Calab_0824	6.553e-29	123.0	COG0295@1|root,COG0295@2|Bacteria,2NPJN@2323|unclassified Bacteria	2|Bacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_2618	dCMP_cyt_deam_1,dCMP_cyt_deam_2
DTH1_k127_2818284_1	1382315.JPOI01000001_gene1963	2.299e-72	256.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DTH1_k127_2818284_6	497964.CfE428DRAFT_5353	3.3e-28	127.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH1_k127_2821006_4	1158292.JPOE01000002_gene3555	1.262e-08	56.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH1_k127_2821006_5	194439.CT1119	6.608e-05	51.0	COG3449@1|root,COG3449@2|Bacteria,1FEK2@1090|Chlorobi	1090|Chlorobi	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
DTH1_k127_2821006_0	1278073.MYSTI_03564	2.147e-226	744.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH1_k127_2821006_3	929562.Emtol_2733	5.433e-22	110.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,47X99@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH1_k127_2821006_2	1303518.CCALI_02844	2.73e-23	106.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
DTH1_k127_2827976_0	661478.OP10G_2213	3.381e-101	344.0	COG1621@1|root,COG4354@1|root,COG1621@2|Bacteria,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
DTH1_k127_2827976_2	1046714.AMRX01000008_gene918	4.284e-11	65.0	COG4030@1|root,COG4030@2|Bacteria,1NSDB@1224|Proteobacteria,1SC1R@1236|Gammaproteobacteria,469NN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH1_k127_2827976_1	1303518.CCALI_02295	6.809e-13	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_2827976_3	278957.ABEA03000144_gene3994	2.045e-06	57.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_2829215_2	452637.Oter_2332	1.399e-35	143.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,3K82A@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
DTH1_k127_2829215_4	880073.Calab_2477	4.448e-07	58.0	2E5Q4@1|root,330ER@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2829215_0	1167006.UWK_00742	3.123e-107	368.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
DTH1_k127_2829215_1	497964.CfE428DRAFT_3459	8.463e-98	330.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
DTH1_k127_2829215_3	237368.SCABRO_01881	1.474e-15	80.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_283091_0	289376.THEYE_A0114	2.374e-166	530.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH1_k127_2847418_3	391625.PPSIR1_34952	1.654e-07	61.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	FHA,Trans_reg_C,Yop-YscD_cpl
DTH1_k127_2847418_2	643562.Daes_0072	1.342e-29	123.0	2DQ60@1|root,334WQ@2|Bacteria,1NADI@1224|Proteobacteria,42WP8@68525|delta/epsilon subdivisions,2WRS6@28221|Deltaproteobacteria,2MD9Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
DTH1_k127_2847418_1	1283300.ATXB01000001_gene2112	1.742e-46	170.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1T12G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2847418_0	323848.Nmul_A2162	7.533e-48	177.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
DTH1_k127_2867523_0	1123277.KB893211_gene4412	1.045e-111	380.0	COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_2867523_2	929703.KE386491_gene2889	3.984e-54	196.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
DTH1_k127_2867523_1	1410653.JHVC01000018_gene2284	6.566e-95	329.0	COG1404@1|root,COG1404@2|Bacteria,1VD5C@1239|Firmicutes,24C2E@186801|Clostridia,36H8D@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH1_k127_2867523_3	886293.Sinac_0056	4.211e-20	105.0	COG1595@1|root,COG1595@2|Bacteria,2J3QA@203682|Planctomycetes	2|Bacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_288537_1	269799.Gmet_2492	1.292e-59	214.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
DTH1_k127_288537_0	497964.CfE428DRAFT_2824	0.0	1335.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2890384_0	1396141.BATP01000060_gene4560	8.758e-174	581.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
DTH1_k127_2890384_2	1123242.JH636435_gene2613	3.537e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH1_k127_2890384_1	1123242.JH636434_gene3764	5.758e-114	383.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_2901689_2	575540.Isop_2812	1.197e-14	79.0	COG0673@1|root,COG0673@2|Bacteria,2IX34@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_2901689_3	493475.GARC_4248	3.617e-07	58.0	2EH3D@1|root,33AVD@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
DTH1_k127_2901689_1	314230.DSM3645_09917	1.605e-23	111.0	COG1082@1|root,COG1082@2|Bacteria,2J21B@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_2901689_0	1121022.ABENE_11795	1.716e-27	117.0	COG1082@1|root,COG1082@2|Bacteria,1NNTS@1224|Proteobacteria	1224|Proteobacteria	G	Alpha-glucosidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97,RicinB_lectin_2
DTH1_k127_2908852_2	344747.PM8797T_00507	2.583e-42	159.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
DTH1_k127_2908852_0	1123242.JH636435_gene1179	2.542e-261	813.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_2908852_1	595460.RRSWK_04657	6.12e-220	687.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_2917225_1	344747.PM8797T_31633	8.882e-96	320.0	COG0555@1|root,COG0555@2|Bacteria,2IYJ3@203682|Planctomycetes	203682|Planctomycetes	O	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
DTH1_k127_2917225_2	344747.PM8797T_31628	3.187e-71	247.0	COG3842@1|root,COG3842@2|Bacteria,2IZ85@203682|Planctomycetes	203682|Planctomycetes	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH1_k127_2917225_0	344747.PM8797T_31618	8.38e-106	357.0	COG0476@1|root,COG0476@2|Bacteria,2IY5K@203682|Planctomycetes	203682|Planctomycetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
DTH1_k127_2917225_3	1396141.BATP01000060_gene4727	2.399e-17	87.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
DTH1_k127_29285_1	1185876.BN8_04770	2.291e-66	241.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_29285_2	471854.Dfer_2640	1.343e-52	194.0	COG1082@1|root,COG1082@2|Bacteria,4NJF5@976|Bacteroidetes,47MRZ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH1_k127_29285_0	742725.HMPREF9450_00266	1.464e-301	954.0	COG3408@1|root,COG3408@2|Bacteria,4NJY8@976|Bacteroidetes,2G2N9@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH1_k127_29285_3	1246445.ANAY01000021_gene1781	0.0007277	51.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
DTH1_k127_2930400_3	497964.CfE428DRAFT_0981	3.426e-59	213.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
DTH1_k127_2930400_1	521674.Plim_1708	7.091e-114	381.0	COG1793@1|root,COG1793@2|Bacteria,2J0I2@203682|Planctomycetes	203682|Planctomycetes	L	secreted glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_2930400_0	1396141.BATP01000029_gene2231	2.774e-159	542.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH1_k127_2930400_2	485918.Cpin_3102	7.42e-60	214.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_2933480_1	1123242.JH636435_gene1136	2.435e-68	238.0	COG1082@1|root,COG2010@1|root,COG2133@1|root,COG1082@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
DTH1_k127_2933480_0	530564.Psta_0173	1.585e-95	330.0	COG0501@1|root,COG3170@1|root,COG0501@2|Bacteria,COG3170@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH1_k127_2933480_2	706587.Desti_1189	3.988e-64	235.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
DTH1_k127_2963868_2	1280950.HJO_06230	2.214e-16	89.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2V7MP@28211|Alphaproteobacteria,44089@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Guanylate_cyc
DTH1_k127_2963868_3	1089545.KB913037_gene8403	4.086e-08	66.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2HSAI@201174|Actinobacteria,4ED2E@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2963868_1	1218084.BBJK01000086_gene5778	1.15e-25	123.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
DTH1_k127_2963868_0	1396141.BATP01000060_gene4727	2.055e-60	222.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
DTH1_k127_2966126_0	880073.Calab_3508	4.126e-122	402.0	COG1446@1|root,COG1446@2|Bacteria,2NPFC@2323|unclassified Bacteria	2|Bacteria	E	Asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DTH1_k127_2966126_2	4555.Si032031m	0.0009014	46.0	COG1233@1|root,2QSIC@2759|Eukaryota,37N2T@33090|Viridiplantae,3GBKK@35493|Streptophyta,3KNEA@4447|Liliopsida,3ID4Z@38820|Poales	35493|Streptophyta	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DTH1_k127_297648_3	452637.Oter_2116	1.913e-45	172.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_297648_4	525146.Ddes_0534	2.336e-06	59.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,2MC24@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH1_k127_297648_1	644282.Deba_0203	6.165e-84	286.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH1_k127_297648_2	1396141.BATP01000007_gene5566	6.532e-70	246.0	COG0767@1|root,COG0767@2|Bacteria,46SXR@74201|Verrucomicrobia,2ITY5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
DTH1_k127_297648_0	886293.Sinac_4596	1.654e-139	454.0	2DBS0@1|root,2ZANT@2|Bacteria,2IY4P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2976894_2	497964.CfE428DRAFT_2419	3.754e-84	282.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia	74201|Verrucomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
DTH1_k127_2976894_5	497964.CfE428DRAFT_5396	8.751e-36	143.0	2DQE3@1|root,3368V@2|Bacteria,46WIA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2976894_6	1403819.BATR01000033_gene1102	1.742e-15	80.0	COG1526@1|root,COG1526@2|Bacteria,46SPA@74201|Verrucomicrobia,2IUBY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FdhD/NarQ family	-	-	-	-	-	-	-	-	-	-	-	-	FdhD-NarQ
DTH1_k127_2976894_3	1396141.BATP01000006_gene5486	3.635e-62	216.0	2DHFW@1|root,2ZZKM@2|Bacteria,46SNY@74201|Verrucomicrobia,2IVW8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2976894_0	497964.CfE428DRAFT_2417	5.361e-162	517.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
DTH1_k127_2976894_1	1382306.JNIM01000001_gene3956	5.549e-99	336.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
DTH1_k127_2976894_4	1122604.JONR01000006_gene2730	4.354e-53	193.0	COG0494@1|root,COG0494@2|Bacteria,1RI3B@1224|Proteobacteria,1S6HR@1236|Gammaproteobacteria,1X60F@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA mismatch repair protein MutT	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
DTH1_k127_2978423_4	497964.CfE428DRAFT_4114	1.935e-59	211.0	COG1043@1|root,COG1043@2|Bacteria,46SD4@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH1_k127_2978423_3	497964.CfE428DRAFT_0111	6.929e-67	251.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_2978423_5	497964.CfE428DRAFT_0110	4.871e-56	200.0	COG1595@1|root,COG1595@2|Bacteria,46VNT@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH1_k127_2978423_0	886293.Sinac_3371	9.965e-286	910.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_2978423_1	497964.CfE428DRAFT_3528	3.314e-255	793.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Laminin_G_3
DTH1_k127_2978423_2	497964.CfE428DRAFT_2433	1.981e-157	508.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
DTH1_k127_3024363_0	497964.CfE428DRAFT_5433	3.21e-20	103.0	COG4409@1|root,COG4409@2|Bacteria,46SCF@74201|Verrucomicrobia	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
DTH1_k127_3024363_2	237609.PSAKL28_18690	0.0007996	51.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD,Thioesterase
DTH1_k127_3024363_1	1209984.BN978_03254	3.254e-17	91.0	COG2020@1|root,COG2020@2|Bacteria,2IIDW@201174|Actinobacteria,238RM@1762|Mycobacteriaceae	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
DTH1_k127_3035153_0	344747.PM8797T_08174	5.821e-143	459.0	COG1574@1|root,COG1574@2|Bacteria,2IX0K@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH1_k127_3035153_1	748247.AZKH_2522	5.709e-129	413.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJFI@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DTH1_k127_3035153_3	1403819.BATR01000182_gene6271	4.95e-74	255.0	COG0778@1|root,COG0778@2|Bacteria,46V9P@74201|Verrucomicrobia,2IU8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Nitroreductase family	-	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
DTH1_k127_3035153_2	1403819.BATR01000053_gene1630	7.992e-82	275.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia,2IU6M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
DTH1_k127_3042092_6	1123274.KB899427_gene3319	8.775e-05	46.0	COG2942@1|root,COG2942@2|Bacteria,2J66W@203691|Spirochaetes	203691|Spirochaetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
DTH1_k127_3042092_0	452637.Oter_4539	4.638e-145	467.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
DTH1_k127_3042092_4	497964.CfE428DRAFT_4678	5.101e-08	66.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
DTH1_k127_3042092_2	880073.Calab_0674	4.083e-12	79.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
DTH1_k127_3042092_1	1121101.HMPREF1532_01876	2.621e-122	416.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FVA6@200643|Bacteroidia,4AT0B@815|Bacteroidaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
DTH1_k127_3042092_3	1192868.CAIU01000040_gene4440	1.488e-08	56.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH1_k127_3042092_5	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
DTH1_k127_3048215_1	497964.CfE428DRAFT_1993	1.825e-44	164.0	COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH1_k127_3048215_2	313612.L8106_03564	1.937e-12	69.0	COG0598@1|root,COG0598@2|Bacteria,1G4WV@1117|Cyanobacteria,1HEGB@1150|Oscillatoriales	1117|Cyanobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
DTH1_k127_3048215_0	497964.CfE428DRAFT_1398	5.156e-242	771.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U11@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_304969_1	886293.Sinac_3173	1.485e-18	91.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rfaY	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_304969_0	1380355.JNIJ01000041_gene5260	2.738e-97	329.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
DTH1_k127_3052621_2	498761.HM1_2111	1.802e-21	95.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DTH1_k127_3052621_1	1121423.JONT01000013_gene346	3.338e-105	349.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH1_k127_3052621_3	1379698.RBG1_1C00001G1401	3.776e-17	91.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
DTH1_k127_3052621_0	1123253.AUBD01000004_gene1089	3.285e-210	664.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1X3IR@135614|Xanthomonadales	135614|Xanthomonadales	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
DTH1_k127_3056950_3	583355.Caka_3040	5.458e-19	93.0	COG0823@1|root,COG0823@2|Bacteria,46XCP@74201|Verrucomicrobia,3K9X8@414999|Opitutae	414999|Opitutae	U	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3056950_4	1122214.AQWH01000036_gene5010	1.006e-14	76.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2PM48@255475|Aurantimonadaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	yhdN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH1_k127_3056950_1	1499967.BAYZ01000012_gene2475	5.784e-90	303.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	ydjG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0019170,GO:0055114	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
DTH1_k127_3056950_0	882378.RBRH_00535	2.058e-112	380.0	COG0308@1|root,COG0308@2|Bacteria,1NQIW@1224|Proteobacteria,2WA6B@28216|Betaproteobacteria,1K252@119060|Burkholderiaceae	28216|Betaproteobacteria	E	beta subunit of N-acylethanolamine-hydrolyzing acid amidase	-	-	-	-	-	-	-	-	-	-	-	-	NAAA-beta,Phospholip_B
DTH1_k127_3056950_2	880526.KE386488_gene1576	2.736e-32	145.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3057917_0	748280.NH8B_1377	0.0	1257.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales	206351|Neisseriales	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
DTH1_k127_3057917_3	1121878.AUGL01000017_gene1759	2.179e-45	170.0	2CWKB@1|root,32SZW@2|Bacteria,1RD54@1224|Proteobacteria,1S4QG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3057917_1	1166018.FAES_1357	2.442e-224	703.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47N60@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
DTH1_k127_3057917_2	1210884.HG799462_gene7872	2.117e-61	221.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DTH1_k127_3057917_4	1280944.HY17_00425	6.439e-25	107.0	COG2273@1|root,COG2273@2|Bacteria,1PG8G@1224|Proteobacteria,2V8W4@28211|Alphaproteobacteria,43XPI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH1_k127_3059425_2	394503.Ccel_0992	1.496e-40	162.0	COG3250@1|root,COG3250@2|Bacteria,1TU92@1239|Firmicutes,248WD@186801|Clostridia,36FQK@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH1_k127_3059425_4	278957.ABEA03000106_gene1817	1.407e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3059425_3	864051.BurJ1DRAFT_3700	3.098e-17	96.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
DTH1_k127_3059425_0	1396141.BATP01000002_gene4846	8.567e-84	302.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
DTH1_k127_3059425_1	1396141.BATP01000002_gene4845	2.762e-58	213.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_3062088_0	344747.PM8797T_29842	3.368e-35	145.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH1_k127_3081559_3	497964.CfE428DRAFT_0845	1.155e-66	230.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH1_k127_3081559_1	478741.JAFS01000002_gene596	1.438e-122	406.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,37G7B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH1_k127_3081559_0	497964.CfE428DRAFT_5386	1.46e-128	420.0	COG2876@1|root,COG2876@2|Bacteria,46SUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
DTH1_k127_3081559_5	497964.CfE428DRAFT_0260	1.448e-56	201.0	COG0822@1|root,COG0822@2|Bacteria,46VAC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
DTH1_k127_3081559_4	497964.CfE428DRAFT_0261	1.281e-59	213.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH1_k127_3081559_2	382464.ABSI01000007_gene4191	6.037e-88	297.0	COG2833@1|root,COG2833@2|Bacteria,46YYE@74201|Verrucomicrobia,2ITUP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
DTH1_k127_3102652_0	497964.CfE428DRAFT_0210	3.447e-138	454.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia	74201|Verrucomicrobia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DTH1_k127_3102652_1	497964.CfE428DRAFT_5484	2.709e-111	374.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH1_k127_3103903_1	1121904.ARBP01000011_gene1396	4.463e-12	79.0	COG1404@1|root,COG1572@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH1_k127_3103903_0	583355.Caka_1736	1.518e-63	234.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_3128321_1	1396418.BATQ01000093_gene5884	5.156e-91	304.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiC-associated domain	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
DTH1_k127_3128321_2	1157490.EL26_10960	2.069e-26	111.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,278HH@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the HesB IscA family	yutM	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
DTH1_k127_3128321_3	1499967.BAYZ01000088_gene5142	1.413e-17	98.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,2NRIW@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
DTH1_k127_3128321_0	1229204.AMYY01000005_gene1541	2.072e-239	756.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,4BP8W@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH1_k127_3152179_2	640511.BC1002_6686	2.639e-33	133.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3152179_0	1396141.BATP01000022_gene356	1.404e-109	366.0	COG0654@1|root,COG0654@2|Bacteria,46WJF@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DTH1_k127_3152179_1	1038859.AXAU01000001_gene3812	6.772e-73	253.0	COG0702@1|root,COG0702@2|Bacteria,1Q5QN@1224|Proteobacteria,2U3R1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
DTH1_k127_317223_2	481448.Minf_1759	4.41e-32	135.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,37GRJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DTH1_k127_317223_1	497964.CfE428DRAFT_0115	2.924e-94	314.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
DTH1_k127_317223_0	330214.NIDE0577	9.325e-313	982.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
DTH1_k127_317682_3	1379698.RBG1_1C00001G0984	0.0002645	47.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
DTH1_k127_317682_2	794903.OPIT5_04765	5.388e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_317682_1	234267.Acid_6615	5.591e-18	95.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3180312_4	1382359.JIAL01000001_gene1944	9.646e-20	90.0	COG3250@1|root,COG3250@2|Bacteria,3Y6RC@57723|Acidobacteria,2JKAB@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH1_k127_3180312_0	556261.HMPREF0240_00553	5.894e-150	482.0	COG0407@1|root,COG0407@2|Bacteria,1UGIQ@1239|Firmicutes,25P0U@186801|Clostridia,36RQW@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_3180312_2	697281.Mahau_1209	4.199e-102	350.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_3180312_1	471854.Dfer_2296	6.776e-130	425.0	COG2152@1|root,COG2152@2|Bacteria,4P1IV@976|Bacteroidetes	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3180312_3	484018.BACPLE_03677	1.423e-43	176.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,2FPEC@200643|Bacteroidia,4AKUZ@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
DTH1_k127_3180312_5	314230.DSM3645_24670	1.368e-17	96.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYJR@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
DTH1_k127_3199158_2	344747.PM8797T_00347	1.225e-112	374.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
DTH1_k127_3199158_1	240016.ABIZ01000001_gene2661	1.831e-171	543.0	COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH1_k127_3199158_4	1121441.AUCX01000016_gene2382	1.256e-42	180.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,42RTP@68525|delta/epsilon subdivisions,2WN9M@28221|Deltaproteobacteria,2M9XH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_8,Response_reg,SpoIIE
DTH1_k127_3199158_0	118168.MC7420_4981	2.437e-186	612.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH1_k127_3199158_6	661478.OP10G_2992	3.044e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_3199158_3	247634.GPB2148_909	9.989e-75	262.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1J6J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Microcin C7 resistance	ldcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641	Peptidase_S66
DTH1_k127_3199158_5	1173028.ANKO01000018_gene1201	2.9e-16	93.0	COG1404@1|root,COG2931@1|root,COG3210@1|root,COG3940@1|root,COG4447@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3940@2|Bacteria,COG4447@2|Bacteria,1G4T5@1117|Cyanobacteria,1HHYV@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,Haemagg_act,HemolysinCabind
DTH1_k127_3199158_7	768706.Desor_1391	2.738e-12	80.0	COG2247@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3386@2|Bacteria,1VMQN@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
DTH1_k127_3201145_2	382464.ABSI01000021_gene419	1.129e-63	221.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DTH1_k127_3201145_1	1267535.KB906767_gene5199	4.197e-109	362.0	COG1082@1|root,COG1082@2|Bacteria,3Y78R@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_3201145_0	794903.OPIT5_18315	2.979e-133	430.0	COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia,3K7KW@414999|Opitutae	414999|Opitutae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DTH1_k127_3205748_1	485913.Krac_6798	2.97e-56	209.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_3205748_0	1403819.BATR01000164_gene5577	5.239e-217	686.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,2ITYS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH1_k127_3217575_0	326297.Sama_0297	2.239e-111	373.0	COG3828@1|root,COG3828@2|Bacteria,1QVR0@1224|Proteobacteria,1SN58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl hydrolase family 99	-	-	3.2.1.130	ko:K15538	-	-	-	-	ko00000,ko01000	-	GH99	-	Glyco_hydro_99
DTH1_k127_3217575_1	1123508.JH636450_gene7204	1.316e-61	233.0	COG0673@1|root,COG0673@2|Bacteria,2IXVF@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_3217575_3	344747.PM8797T_17187	6.99e-07	62.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3217575_2	234267.Acid_7405	6.727e-61	220.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
DTH1_k127_3226138_5	521011.Mpal_2572	7.831e-67	235.0	COG4063@1|root,arCOG03221@2157|Archaea	2157|Archaea	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA-2	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
DTH1_k127_3226138_6	1283300.ATXB01000001_gene1577	4.532e-44	167.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH1_k127_3226138_15	1283300.ATXB01000001_gene1577	1.269e-15	79.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH1_k127_3226138_1	478741.JAFS01000001_gene1976	5.099e-147	477.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
DTH1_k127_3226138_8	1156937.MFUM_270017	5.351e-30	132.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,37GID@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
DTH1_k127_3226138_18	1112216.JH594425_gene2614	0.0001643	51.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG4566@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG4566@2|Bacteria,1NRP8@1224|Proteobacteria,2TWP9@28211|Alphaproteobacteria,2KETS@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GerE,HATPase_c,HisKA,PAS_10,Response_reg
DTH1_k127_3226138_14	794903.OPIT5_07895	2.691e-16	80.0	COG2331@1|root,COG2331@2|Bacteria,46ZFV@74201|Verrucomicrobia,3K8G5@414999|Opitutae	414999|Opitutae	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3226138_0	530564.Psta_1209	1.385e-216	696.0	COG0003@1|root,COG0003@2|Bacteria,2IY37@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM arsenite-activated ATPase (arsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
DTH1_k127_3226138_9	1269813.ATUL01000021_gene759	3.876e-27	127.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor arsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
DTH1_k127_3226138_3	556269.ACDQ01000009_gene1948	2.403e-95	331.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
DTH1_k127_3226138_17	1280953.HOC_18234	6.001e-07	55.0	2EPBI@1|root,33GYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3226138_4	1396141.BATP01000003_gene5267	5.248e-71	244.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
DTH1_k127_3226138_7	278957.ABEA03000004_gene4516	1.147e-33	136.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
DTH1_k127_3226138_13	1408428.JNJP01000055_gene143	1.21e-18	91.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria,2MC9Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DTH1_k127_3226138_16	521674.Plim_0147	7.594e-08	61.0	2DMHQ@1|root,32RMG@2|Bacteria,2J02C@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
DTH1_k127_3226138_12	1304885.AUEY01000001_gene3204	5.788e-20	101.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3226138_11	402880.MmarC5_0718	3.513e-21	102.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23QEP@183939|Methanococci	183939|Methanococci	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH1_k127_3226138_2	909663.KI867150_gene1425	2.055e-101	334.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DTH1_k127_3240540_3	1500281.JQKZ01000022_gene837	0.0001565	52.0	COG3637@1|root,COG3637@2|Bacteria,4PKKK@976|Bacteroidetes,1HYEJ@117743|Flavobacteriia,3ZP50@59732|Chryseobacterium	976|Bacteroidetes	M	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
DTH1_k127_3240540_1	247639.MGP2080_02111	3.519e-31	132.0	COG2067@1|root,COG2067@2|Bacteria,1NDQA@1224|Proteobacteria,1TIWZ@1236|Gammaproteobacteria,1JBA2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3240540_0	497964.CfE428DRAFT_5778	3.849e-105	351.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
DTH1_k127_3240540_2	1304885.AUEY01000019_gene1169	1.913e-08	63.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DTH1_k127_3252099_2	1396141.BATP01000004_gene5820	2.74e-59	217.0	COG0551@1|root,COG0551@2|Bacteria,46SJD@74201|Verrucomicrobia,2IVAK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
DTH1_k127_3252099_1	292563.Cyast_2134	1.998e-59	214.0	COG0642@1|root,COG2205@2|Bacteria,1G3D2@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
DTH1_k127_3252099_3	575540.Isop_1515	4.296e-45	176.0	COG1975@1|root,COG1975@2|Bacteria,2IXRN@203682|Planctomycetes	203682|Planctomycetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
DTH1_k127_3252099_6	1173263.Syn7502_01724	1.218e-10	66.0	COG4634@1|root,COG4634@2|Bacteria,1GA41@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3252099_5	1173023.KE650771_gene588	1.074e-17	84.0	COG2442@1|root,COG2442@2|Bacteria,1G9FC@1117|Cyanobacteria,1JMBK@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
DTH1_k127_3252099_0	237368.SCABRO_01787	2.812e-131	436.0	COG2963@1|root,COG3335@1|root,COG2963@2|Bacteria,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_28,HTH_Tnp_1
DTH1_k127_3252099_7	118161.KB235918_gene5	9.142e-10	63.0	2DTC9@1|root,33JP3@2|Bacteria,1GB2W@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3256052_4	1120792.JAFV01000001_gene1790	8.432e-29	128.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
DTH1_k127_3256052_3	316056.RPC_4535	3.657e-44	171.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TTR3@28211|Alphaproteobacteria,3JR5N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
DTH1_k127_3256052_2	349521.HCH_05416	2.617e-58	215.0	COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,1RN60@1236|Gammaproteobacteria,1XJ0F@135619|Oceanospirillales	135619|Oceanospirillales	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
DTH1_k127_3256052_0	1142394.PSMK_04700	1.234e-167	546.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
DTH1_k127_3256052_1	1121904.ARBP01000032_gene2006	1.481e-110	386.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,47RDC@768503|Cytophagia	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
DTH1_k127_3256053_4	1242864.D187_007480	7.408e-08	57.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
DTH1_k127_3256053_2	1283284.AZUK01000001_gene812	5.564e-30	123.0	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,1RU3S@1236|Gammaproteobacteria,1Y501@135624|Aeromonadales	135624|Aeromonadales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
DTH1_k127_3256053_3	382464.ABSI01000005_gene1380	3.587e-09	68.0	2B7DQ@1|root,320HD@2|Bacteria,46XRQ@74201|Verrucomicrobia,2IWFK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3256053_0	243090.RB7928	4.496e-155	526.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,2IY76@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RDD
DTH1_k127_3256053_1	497964.CfE428DRAFT_2982	6.955e-67	238.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH1_k127_3281406_1	1142394.PSMK_11740	1.921e-09	68.0	COG2165@1|root,COG2165@2|Bacteria,2IXWH@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_3281406_0	497964.CfE428DRAFT_0840	7.807e-57	205.0	COG3011@1|root,COG3011@2|Bacteria,46U84@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
DTH1_k127_3287269_3	1185876.BN8_02520	2.94e-08	63.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,4NN1P@976|Bacteroidetes,47T2G@768503|Cytophagia	976|Bacteroidetes	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3287269_2	1122919.KB905591_gene4021	4.655e-61	229.0	COG1520@1|root,COG1520@2|Bacteria,1UIHU@1239|Firmicutes,4ISIB@91061|Bacilli,2773B@186822|Paenibacillaceae	91061|Bacilli	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3287269_0	794903.OPIT5_28170	3.096e-210	668.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
DTH1_k127_3287269_1	435591.BDI_2467	1.013e-90	315.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,2FNQN@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
DTH1_k127_3290413_2	1408254.T458_20750	2.336e-13	74.0	COG0654@1|root,COG0654@2|Bacteria,1UZNW@1239|Firmicutes,4HB88@91061|Bacilli,26VD7@186822|Paenibacillaceae	91061|Bacilli	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DTH1_k127_3290413_1	697282.Mettu_0535	8.823e-43	166.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DTH1_k127_3290413_0	756272.Plabr_0697	2.775e-45	176.0	2DBTJ@1|root,2ZAYX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DTH1_k127_3303239_1	1265505.ATUG01000002_gene1309	1.006e-65	228.0	COG0160@1|root,COG0160@2|Bacteria,1QTZ3@1224|Proteobacteria,43D42@68525|delta/epsilon subdivisions,2X8AU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH1_k127_3303239_3	329726.AM1_2164	1.579e-16	82.0	COG1100@1|root,COG2319@1|root,COG4916@1|root,COG1100@2|Bacteria,COG2319@2|Bacteria,COG4916@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
DTH1_k127_3303239_4	247490.KSU1_D0453	6.142e-05	47.0	2EGSE@1|root,33AII@2|Bacteria,2J3TB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3303239_0	1142394.PSMK_12900	4.244e-87	312.0	COG2103@1|root,COG2103@2|Bacteria	2|Bacteria	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
DTH1_k127_3303239_2	382464.ABSI01000011_gene2535	2.471e-53	194.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DTH1_k127_3313789_0	497964.CfE428DRAFT_3817	2.734e-162	518.0	COG1690@1|root,COG1690@2|Bacteria,46SU0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
DTH1_k127_3314868_3	886293.Sinac_3363	1.072e-26	123.0	COG4299@1|root,COG4299@2|Bacteria,2IYKU@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH1_k127_3314868_2	1294143.H681_11855	3.414e-30	134.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RZB6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
DTH1_k127_3314868_0	404589.Anae109_4094	0.0	1174.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
DTH1_k127_3314868_1	768671.ThimaDRAFT_4573	3.547e-31	125.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,1T9ZT@1236|Gammaproteobacteria,1WYMB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
DTH1_k127_332862_0	1054213.HMPREF9946_02237	2.376e-33	137.0	COG3056@1|root,COG3056@2|Bacteria,1NKTA@1224|Proteobacteria,2UT4N@28211|Alphaproteobacteria,2JX6F@204441|Rhodospirillales	204441|Rhodospirillales	M	Uncharacterized lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_16
DTH1_k127_3331425_1	595460.RRSWK_05050	1.944e-62	219.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH1_k127_3331425_5	69014.TK0917	4.552e-11	66.0	COG2886@1|root,arCOG00722@2157|Archaea,2Y0J3@28890|Euryarchaeota,244GE@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
DTH1_k127_3331425_7	395961.Cyan7425_2060	0.0002688	44.0	COG2405@1|root,COG2405@2|Bacteria,1G6NZ@1117|Cyanobacteria,3KKNI@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF3368)	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
DTH1_k127_3331425_6	278963.ATWD01000001_gene2663	0.0002416	44.0	COG2405@1|root,COG2405@2|Bacteria,3Y95W@57723|Acidobacteria,2JNS5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
DTH1_k127_3331425_4	1303518.CCALI_00532	4.572e-20	99.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
DTH1_k127_3331425_3	272123.Anacy_4446	3.153e-20	93.0	COG2442@1|root,COG2442@2|Bacteria,1G7T6@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
DTH1_k127_3331425_2	1499967.BAYZ01000141_gene6156	2.366e-38	146.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
DTH1_k127_3331425_0	522306.CAP2UW1_3000	2.981e-68	239.0	28IHG@1|root,2Z8IP@2|Bacteria,1R4RG@1224|Proteobacteria,2VVIT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3340683_0	595460.RRSWK_03373	1.058e-235	745.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Beta_helix,PDZ_2,PEGA,Trypsin_2
DTH1_k127_3340683_1	530564.Psta_1668	7.835e-116	384.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_3361584_6	761193.Runsl_3310	4.792e-21	106.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_3361584_1	497964.CfE428DRAFT_4312	8.686e-100	334.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
DTH1_k127_3361584_0	240016.ABIZ01000001_gene1668	7.811e-157	501.0	COG3239@1|root,COG3239@2|Bacteria,46SX7@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid desaturase	desA	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH1_k127_3361584_5	497964.CfE428DRAFT_6672	1.055e-21	100.0	COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH1_k127_3361584_3	497964.CfE428DRAFT_6673	2.585e-37	144.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH1_k127_3361584_2	1268635.Loa_01459	4.826e-80	271.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria,1JD7P@118969|Legionellales	118969|Legionellales	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DTH1_k127_3361584_4	56780.SYN_00581	2.813e-31	127.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
DTH1_k127_3370757_3	395493.BegalDRAFT_0204	3.646e-18	86.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,4615Z@72273|Thiotrichales	72273|Thiotrichales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH1_k127_3370757_1	497964.CfE428DRAFT_6050	5.539e-117	383.0	COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
DTH1_k127_3370757_0	1191523.MROS_1318	7.574e-133	439.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH1_k127_3370757_2	1038862.KB893840_gene976	8.286e-50	184.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria,3JYJ9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH1_k127_3377207_2	1396141.BATP01000028_gene2287	3.573e-97	323.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria,46WKF@74201|Verrucomicrobia,2IVDI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,HEAT_2,Lipase_GDSL_2
DTH1_k127_3377207_7	498211.CJA_2236	2.744e-09	61.0	COG1396@1|root,COG1396@2|Bacteria,1R0M5@1224|Proteobacteria,1TBAA@1236|Gammaproteobacteria,1FHSR@10|Cellvibrio	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DTH1_k127_3377207_3	316274.Haur_2251	3.184e-31	144.0	COG1629@1|root,COG3055@1|root,COG1629@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Kelch_1,Plug
DTH1_k127_3377207_6	522373.Smlt0682	3.008e-11	74.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1X5BZ@135614|Xanthomonadales	135614|Xanthomonadales	G	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Calx-beta,Glyco_hydro_18,fn3
DTH1_k127_3377207_1	1396418.BATQ01000014_gene4352	6.585e-151	485.0	COG3616@1|root,COG3616@2|Bacteria,46TAP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
DTH1_k127_3377207_5	661478.OP10G_4802	4.2e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_3377207_0	240016.ABIZ01000001_gene3033	0.0	1129.0	COG2010@1|root,COG2010@2|Bacteria,46TQ0@74201|Verrucomicrobia,2ITRS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_3377207_8	504487.JCM19302_1724	1.598e-07	59.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH1_k127_3377207_4	886293.Sinac_6958	4.328e-23	100.0	COG1524@1|root,COG1524@2|Bacteria,2J563@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_3379556_2	1268068.PG5_29530	9.711e-12	65.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH1_k127_3379556_0	317936.Nos7107_1299	6.799e-179	568.0	COG0579@1|root,COG0579@2|Bacteria,1G0XV@1117|Cyanobacteria,1HIW2@1161|Nostocales	1117|Cyanobacteria	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
DTH1_k127_3379556_1	395495.Lcho_1395	4.713e-33	134.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VQBN@28216|Betaproteobacteria,1KKM2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
DTH1_k127_3389720_0	573413.Spirs_4003	1.457e-191	620.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH1_k127_3389720_2	1121447.JONL01000003_gene3289	8.548e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria,42VPE@68525|delta/epsilon subdivisions,2WRZ3@28221|Deltaproteobacteria,2MBFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
DTH1_k127_3389720_1	886293.Sinac_7042	2.138e-191	622.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
DTH1_k127_3395471_0	243090.RB11084	1.909e-279	874.0	COG0457@1|root,COG0795@1|root,COG0457@2|Bacteria,COG0795@2|Bacteria,2IXP3@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_16
DTH1_k127_3395471_1	861299.J421_1753	8.601e-11	69.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH1_k127_3412102_0	1122605.KB893625_gene1943	4.997e-83	287.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1IUUU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH1_k127_3412102_1	1121920.AUAU01000009_gene1881	1.774e-38	162.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH1_k127_3419360_0	583355.Caka_3117	9.355e-214	694.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Beta_helix,DUF1565
DTH1_k127_3419360_1	471854.Dfer_4144	1.6e-38	152.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_3423879_0	1121930.AQXG01000001_gene1486	5.358e-111	369.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1INYZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH1_k127_3423879_1	497964.CfE428DRAFT_1931	1.331e-91	310.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH1_k127_3423879_2	105559.Nwat_2046	5.134e-74	250.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH1_k127_3428900_3	861299.J421_2229	9.324e-19	87.0	COG3525@1|root,COG3525@2|Bacteria,1ZT3V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
DTH1_k127_3428900_2	180332.JTGN01000003_gene1997	1.793e-40	169.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_3428900_0	443143.GM18_2242	6.237e-103	356.0	COG2730@1|root,COG2730@2|Bacteria,1R4XH@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH1_k127_3428900_1	794903.OPIT5_03205	4.245e-91	305.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,3K7EN@414999|Opitutae	414999|Opitutae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
DTH1_k127_3432360_0	497964.CfE428DRAFT_2729	2.562e-54	196.0	COG1209@1|root,COG1209@2|Bacteria,46T9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Nucleotidyl transferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH1_k127_3432360_2	1123247.AUIJ01000005_gene313	2.267e-29	130.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH1_k127_3432360_4	324602.Caur_0299	3.475e-11	75.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
DTH1_k127_3432360_3	870187.Thini_1532	2.904e-17	94.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Cadherin_3,Calx-beta,DUF4347,He_PIG,Invasin_D3,Laminin_G_3,Lectin_C,PA14,Pentaxin,Peptidase_S74
DTH1_k127_3432360_5	316274.Haur_2191	5.917e-10	66.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K11904,ko:K12132	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02044	3.A.23.1	-	-	DUF1565,DUF3494,Pkinase,SLH,TadE
DTH1_k127_3432360_1	762968.HMPREF9441_02048	8.666e-53	187.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,2FNBD@200643|Bacteroidia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DTH1_k127_3433949_0	1408813.AYMG01000012_gene1033	1.47e-185	588.0	COG3250@1|root,COG3250@2|Bacteria,4PN2B@976|Bacteroidetes,1IQ6X@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Glyco_hydro_2_N
DTH1_k127_3433949_1	1123278.KB893574_gene6157	3.921e-126	419.0	COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes,47R5K@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20b
DTH1_k127_3453599_0	1396418.BATQ01000117_gene4594	9.417e-124	404.0	2DBKQ@1|root,2Z9U7@2|Bacteria,46XD4@74201|Verrucomicrobia,2IVHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3453599_3	1232437.KL662027_gene2817	1.762e-06	60.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQGJ@28221|Deltaproteobacteria,2MKF4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH1_k127_3453599_2	794903.OPIT5_30270	1.142e-22	108.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	mauE	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
DTH1_k127_3453599_1	1192034.CAP_5545	1.494e-100	334.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH1_k127_3461478_2	1329516.JPST01000001_gene934	2.72e-29	117.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4HBUQ@91061|Bacilli,27B1T@186824|Thermoactinomycetaceae	91061|Bacilli	E	Thermophilic metalloprotease (M29)	ampS5	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
DTH1_k127_3461478_1	1183438.GKIL_2152	7.474e-98	336.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH1_k127_3461478_0	1379698.RBG1_1C00001G1671	5.026e-151	497.0	COG1228@1|root,COG1228@2|Bacteria,2NPD9@2323|unclassified Bacteria	2|Bacteria	Q	Amidohydrolase family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DTH1_k127_34810_6	404589.Anae109_1185	8.103e-20	91.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
DTH1_k127_34810_1	56780.SYN_00905	6.64e-172	557.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2MQBJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
DTH1_k127_34810_3	443143.GM18_1309	5.207e-40	156.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
DTH1_k127_34810_2	756499.Desde_1902	2.412e-164	533.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
DTH1_k127_34810_4	321332.CYB_1025	2.166e-39	149.0	COG0607@1|root,COG0607@2|Bacteria,1GPXG@1117|Cyanobacteria,1H0XW@1129|Synechococcus	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH1_k127_34810_5	530564.Psta_0575	8.473e-37	143.0	COG0662@1|root,COG0662@2|Bacteria,2J4Q9@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH1_k127_34810_0	761193.Runsl_5537	2.652e-218	687.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,4NK15@976|Bacteroidetes,47MMH@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SGL
DTH1_k127_3499895_1	234267.Acid_2265	5.099e-205	643.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_3499895_0	234267.Acid_2266	8.769e-219	704.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
DTH1_k127_3499895_3	1122135.KB893134_gene3934	8.042e-57	207.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
DTH1_k127_3499895_2	1122135.KB893134_gene3933	2.487e-95	320.0	COG0518@1|root,COG0518@2|Bacteria,1Q2PQ@1224|Proteobacteria,2U196@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DTH1_k127_3510655_4	452637.Oter_2093	2.093e-12	68.0	COG0828@1|root,COG0828@2|Bacteria,46WBR@74201|Verrucomicrobia,3K8F7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
DTH1_k127_3510655_2	497964.CfE428DRAFT_1667	4.572e-75	263.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_3510655_1	1396418.BATQ01000091_gene5765	1.395e-121	406.0	COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia,2ITTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Poly A polymerase head domain	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
DTH1_k127_3510655_0	382464.ABSI01000010_gene3676	1.026e-153	499.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,2IU0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
DTH1_k127_3510655_3	391623.TERMP_00885	1.29e-46	178.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH1_k127_3510655_6	47839.CCAU010000018_gene4176	0.000313	53.0	COG2244@1|root,COG2244@2|Bacteria,2I8M1@201174|Actinobacteria,2372Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3510655_5	1210884.HG799462_gene8751	4.284e-11	64.0	COG0624@1|root,COG0624@2|Bacteria,2IYA5@203682|Planctomycetes	203682|Planctomycetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DTH1_k127_3517900_0	497964.CfE428DRAFT_4539	1.104e-258	810.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
DTH1_k127_3517900_2	1089549.AZUQ01000001_gene203	4.071e-43	170.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4EXWS@85014|Glycomycetales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
DTH1_k127_3517900_1	886293.Sinac_2390	1.159e-232	729.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_352318_0	717606.PaecuDRAFT_2033	1.032e-49	194.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DTH1_k127_352318_2	243090.RB10666	7.894e-21	109.0	COG1361@1|root,COG1361@2|Bacteria,2IYS8@203682|Planctomycetes	203682|Planctomycetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DTH1_k127_352318_1	331678.Cphamn1_2540	1.817e-42	158.0	2DNV7@1|root,32ZAW@2|Bacteria	2|Bacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH1_k127_352318_3	1396418.BATQ01000041_gene6297	2.405e-07	54.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia,2ITM8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
DTH1_k127_3556957_4	574087.Acear_1299	1.369e-45	171.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia	186801|Clostridia	E	PFAM dihydropteroate synthase, DHPS	acsE	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DTH1_k127_3556957_3	1540257.JQMW01000013_gene1215	5.769e-46	179.0	COG1810@1|root,COG1810@2|Bacteria,1V28Y@1239|Firmicutes,24DXC@186801|Clostridia,36DES@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF166
DTH1_k127_3556957_2	42256.RradSPS_2576	2.03e-84	288.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DTH1_k127_3556957_5	1123009.AUID01000009_gene494	6.201e-41	157.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
DTH1_k127_3556957_1	1042877.GQS_04965	2.086e-236	751.0	COG1894@1|root,COG4231@1|root,arCOG01609@2157|Archaea,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota,243V2@183968|Thermococci	183968|Thermococci	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
DTH1_k127_3556957_0	903818.KI912268_gene1122	0.0	1129.0	COG3383@1|root,COG3383@2|Bacteria,3Y2KP@57723|Acidobacteria	57723|Acidobacteria	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
DTH1_k127_3556957_6	1121403.AUCV01000002_gene556	7.729e-05	48.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2MHRX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH1_k127_3564678_2	243090.RB728	0.0001061	54.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
DTH1_k127_3564678_1	742725.HMPREF9450_01131	3.82e-74	262.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,2FPEC@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
DTH1_k127_3564678_0	1122605.KB893648_gene3690	1.085e-110	374.0	28J61@1|root,2Z91S@2|Bacteria,4NKJU@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
DTH1_k127_3592687_1	945713.IALB_0431	5.572e-58	213.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DTH1_k127_3592687_0	278957.ABEA03000027_gene1659	5.223e-86	298.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
DTH1_k127_3619750_3	368408.Tpen_1559	3.062e-13	70.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3619750_0	218284.CCDN010000001_gene723	3.367e-32	143.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
DTH1_k127_3619750_1	482537.XP_008561699.1	2.592e-30	136.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTYV@33213|Bilateria,47YVC@7711|Chordata,497BX@7742|Vertebrata,3JCD1@40674|Mammalia,35A0A@314146|Euarchontoglires	33208|Metazoa	T	positive regulation of presynaptic membrane organization	LRP4	GO:0000902,GO:0000904,GO:0001655,GO:0001822,GO:0001932,GO:0001934,GO:0001941,GO:0001942,GO:0003002,GO:0003674,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007389,GO:0007399,GO:0007416,GO:0007528,GO:0008104,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009893,GO:0009950,GO:0009953,GO:0009954,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010648,GO:0010721,GO:0010769,GO:0010771,GO:0010975,GO:0010977,GO:0014069,GO:0016020,GO:0016043,GO:0016055,GO:0016358,GO:0017147,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022404,GO:0022405,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030278,GO:0030279,GO:0030326,GO:0030424,GO:0030425,GO:0030971,GO:0031175,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031399,GO:0031401,GO:0031594,GO:0032268,GO:0032270,GO:0032279,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034185,GO:0034613,GO:0035107,GO:0035108,GO:0035113,GO:0036477,GO:0038023,GO:0040007,GO:0042303,GO:0042325,GO:0042327,GO:0042475,GO:0042476,GO:0042633,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042995,GO:0043005,GO:0043025,GO:0043113,GO:0043226,GO:0043235,GO:0043588,GO:0043679,GO:0043933,GO:0044085,GO:0044091,GO:0044297,GO:0044306,GO:0044332,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045937,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048736,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050770,GO:0050771,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051093,GO:0051124,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051641,GO:0051668,GO:0051716,GO:0051960,GO:0051961,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060828,GO:0061024,GO:0065003,GO:0065007,GO:0065008,GO:0070727,GO:0071340,GO:0071709,GO:0071840,GO:0071944,GO:0072001,GO:0072657,GO:0080090,GO:0090090,GO:0097060,GO:0097090,GO:0097104,GO:0097105,GO:0097110,GO:0097447,GO:0097458,GO:0098590,GO:0098773,GO:0098793,GO:0098794,GO:0098984,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099175,GO:0099572,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:0198738,GO:1901626,GO:1901628,GO:1901629,GO:1901631,GO:1903827,GO:1903829,GO:1903909,GO:1903911,GO:1904393,GO:1904395,GO:1904396,GO:1904398,GO:1905114,GO:1905475,GO:1905477,GO:1990709,GO:1990782,GO:2000026	-	ko:K20051	-	-	-	-	ko00000,ko04131	-	-	-	EGF_CA,FXa_inhibition,Ldl_recept_a,Ldl_recept_b,cEGF
DTH1_k127_3619750_2	938709.AUSH02000027_gene1961	2.969e-19	102.0	COG3405@1|root,COG4886@1|root,COG3405@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_15,CHU_C,DUF11,Flg_new,I-set,Laminin_G_3,fn3
DTH1_k127_3645588_2	1286106.MPL1_00887	1.515e-25	113.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH1_k127_3645588_3	1217656.F964_03877	1.254e-24	114.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria,3NKGV@468|Moraxellaceae	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
DTH1_k127_3645588_1	1403819.BATR01000112_gene3842	4.869e-74	258.0	COG0745@1|root,COG0745@2|Bacteria	1403819.BATR01000112_gene3842|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3645588_0	240016.ABIZ01000001_gene5833	1.003e-82	289.0	COG0642@1|root,COG2205@2|Bacteria,46V7H@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DTH1_k127_3653957_3	1298867.AUES01000018_gene4117	2.581e-27	111.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,2TVAP@28211|Alphaproteobacteria,3JRAG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
DTH1_k127_3653957_1	1298867.AUES01000063_gene24	9.877e-63	226.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DTH1_k127_3653957_2	1267533.KB906737_gene1998	3.254e-50	186.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3653957_0	1267534.KB906760_gene1239	1.071e-142	466.0	COG4325@1|root,COG4325@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
DTH1_k127_3653957_4	1397527.Q670_02705	2.601e-24	114.0	COG3637@1|root,COG3637@2|Bacteria,1NE9Q@1224|Proteobacteria,1T3ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3660122_1	357808.RoseRS_3616	7.813e-106	356.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
DTH1_k127_3660122_2	497964.CfE428DRAFT_2508	2.109e-77	263.0	COG0066@1|root,COG0066@2|Bacteria,46TAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
DTH1_k127_3660122_0	661478.OP10G_1743	8.664e-222	707.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127,RicinB_lectin_2
DTH1_k127_3679752_3	234267.Acid_2457	1.501e-15	79.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	polX	-	-	ko:K02347,ko:K04477	-	-	-	-	ko00000,ko03400	-	-	-	HHH_8,PHP
DTH1_k127_3679752_1	88036.EFJ24329	6.318e-57	206.0	COG0637@1|root,KOG2177@1|root,KOG2177@2759|Eukaryota,KOG2914@2759|Eukaryota,37MAK@33090|Viridiplantae,3GD1A@35493|Streptophyta	35493|Streptophyta	O	NHL repeat-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066	-	-	-	-	-	-	-	-	-	-	HAD_2,NHL,Thioredoxin_8
DTH1_k127_3679752_4	608538.HTH_0820	6.1e-08	58.0	COG0268@1|root,COG0268@2|Bacteria,2G49M@200783|Aquificae	200783|Aquificae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
DTH1_k127_3679752_5	452637.Oter_0873	3.61e-06	53.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
DTH1_k127_3679752_2	497964.CfE428DRAFT_6371	5.824e-17	83.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
DTH1_k127_3679752_0	452637.Oter_0871	5.225e-178	581.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
DTH1_k127_368194_7	543728.Vapar_0410	0.0001101	52.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSMV@28216|Betaproteobacteria,4AEE0@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
DTH1_k127_368194_2	278957.ABEA03000094_gene4754	3.835e-49	184.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH1_k127_368194_1	278957.ABEA03000094_gene4751	4.514e-54	192.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia,3K7ZP@414999|Opitutae	414999|Opitutae	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
DTH1_k127_368194_3	324602.Caur_2619	2.004e-48	177.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_368194_0	497964.CfE428DRAFT_2513	3.791e-189	604.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
DTH1_k127_368194_4	497964.CfE428DRAFT_4931	1.774e-31	139.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
DTH1_k127_368194_5	335543.Sfum_2943	1.12e-12	73.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
DTH1_k127_3684778_0	1307759.JOMJ01000004_gene2829	5.174e-135	442.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria,2MBAU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
DTH1_k127_3684778_10	1448139.AI20_18275	0.0008665	48.0	COG2207@1|root,COG2207@2|Bacteria,1QTTB@1224|Proteobacteria,1T1GI@1236|Gammaproteobacteria,1Y5WC@135624|Aeromonadales	135624|Aeromonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
DTH1_k127_3684778_4	883080.HMPREF9697_03953	4e-25	111.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2VGZ3@28211|Alphaproteobacteria,3JZA4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
DTH1_k127_3684778_5	562970.Btus_3182	8.382e-11	65.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
DTH1_k127_3684778_8	1469607.KK073768_gene4628	0.0004793	45.0	2EHRH@1|root,33BH9@2|Bacteria,1GA8J@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
DTH1_k127_3684778_7	1492922.GY26_17225	0.0003676	45.0	COG2944@1|root,COG2944@2|Bacteria,1NH2C@1224|Proteobacteria,1TBCJ@1236|Gammaproteobacteria,1JBN2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
DTH1_k127_3684778_1	1396141.BATP01000006_gene5432	6.034e-114	394.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH1_k127_3684778_3	167539.Pro_1266	3.215e-34	140.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH1_k127_3684778_2	167539.Pro_1264	6.453e-41	160.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
DTH1_k127_3684778_9	1101192.KB910516_gene2785	0.0008562	43.0	COG0265@1|root,COG0265@2|Bacteria,1MV63@1224|Proteobacteria,2TS54@28211|Alphaproteobacteria,1JRCY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Trypsin_2
DTH1_k127_3684778_6	1229487.AMYW01000032_gene3041	1.443e-07	61.0	COG1361@1|root,COG3210@1|root,COG3291@1|root,COG4932@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
DTH1_k127_3687109_1	204669.Acid345_3430	1.27e-23	102.0	COG0673@1|root,COG0673@2|Bacteria,3Y3FR@57723|Acidobacteria,2JKWF@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_3687109_0	595460.RRSWK_04532	1.15e-186	591.0	COG0673@1|root,COG0673@2|Bacteria,2IXPT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_3687109_3	530564.Psta_3258	1.114e-10	63.0	COG1363@1|root,COG1363@2|Bacteria,2IXMY@203682|Planctomycetes	203682|Planctomycetes	G	COG1363 Cellulase M and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH1_k127_3707711_4	1283284.AZUK01000001_gene1086	0.0004557	49.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1Y3N2@135624|Aeromonadales	135624|Aeromonadales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
DTH1_k127_3707711_3	452637.Oter_1613	8.89e-19	87.0	2BFNH@1|root,329GX@2|Bacteria,46WJ5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
DTH1_k127_3707711_1	452637.Oter_1612	2.247e-38	150.0	COG0526@1|root,COG0526@2|Bacteria,46W0W@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
DTH1_k127_3707711_0	452637.Oter_1611	4.59e-109	364.0	COG1477@1|root,COG1477@2|Bacteria,46V6N@74201|Verrucomicrobia,3K9VB@414999|Opitutae	414999|Opitutae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH1_k127_3707711_2	382464.ABSI01000012_gene2160	8.695e-25	107.0	COG2831@1|root,COG2831@2|Bacteria,46TZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
DTH1_k127_3712072_0	1396141.BATP01000057_gene3053	1.497e-157	541.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH1_k127_3712072_1	414684.RC1_4050	0.0001718	51.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
DTH1_k127_3717991_5	1499967.BAYZ01000013_gene6462	3.878e-32	130.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH1_k127_3717991_1	234267.Acid_7735	1.45e-161	518.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH1_k127_3717991_4	706587.Desti_0559	8.246e-35	143.0	COG1225@1|root,COG1225@2|Bacteria,1NZF4@1224|Proteobacteria,42ZRX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3717991_0	293826.Amet_3280	3.413e-182	581.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,36F9T@31979|Clostridiaceae	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH1_k127_3717991_2	382464.ABSI01000020_gene153	1.652e-51	190.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3717991_3	1396141.BATP01000023_gene616	5.419e-48	181.0	2B5SN@1|root,31YNB@2|Bacteria,46XHC@74201|Verrucomicrobia,2IVXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3718805_0	1396141.BATP01000040_gene2082	4.416e-223	712.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH1_k127_372472_2	497964.CfE428DRAFT_1789	1.883e-34	135.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DTH1_k127_372472_3	247490.KSU1_C0931	1.21e-21	98.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DTH1_k127_372472_1	264732.Moth_0582	2.527e-79	280.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH1_k127_372472_0	497964.CfE428DRAFT_3913	2.07e-165	530.0	COG3119@1|root,COG3119@2|Bacteria,46TFH@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_375146_1	497964.CfE428DRAFT_5992	3.564e-84	284.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
DTH1_k127_375146_2	1396418.BATQ01000011_gene4474	5.413e-77	262.0	COG3576@1|root,COG3576@2|Bacteria,46SQM@74201|Verrucomicrobia,2IVR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
DTH1_k127_375146_5	1267534.KB906760_gene1563	9.717e-15	77.0	29A7N@1|root,2ZX8K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_375146_3	497964.CfE428DRAFT_5990	1.067e-38	153.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_375146_0	861299.J421_1876	5.753e-184	594.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
DTH1_k127_375146_6	344747.PM8797T_01589	4.057e-06	58.0	COG3266@1|root,COG3266@2|Bacteria,2IZW5@203682|Planctomycetes	203682|Planctomycetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_375146_4	1185653.A1A1_08864	1.801e-18	98.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26EYU@186818|Planococcaceae	91061|Bacilli	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH1_k127_3755017_3	857087.Metme_0310	2.912e-19	89.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1XEDR@135618|Methylococcales	135618|Methylococcales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_3755017_1	357804.Ping_3708	2.865e-117	393.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,2QJ8J@267894|Psychromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_3755017_0	497964.CfE428DRAFT_6681	2.711e-184	589.0	COG0535@1|root,COG0535@2|Bacteria,46V38@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
DTH1_k127_3755017_2	497964.CfE428DRAFT_2907	1.964e-89	302.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DTH1_k127_3757694_4	1121123.AUAO01000003_gene2394	4.929e-20	94.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2KIF5@204458|Caulobacterales	204458|Caulobacterales	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
DTH1_k127_3757694_0	886293.Sinac_5714	7.575e-247	796.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYA8@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_3757694_2	448385.sce7786	1.626e-152	497.0	COG3104@1|root,COG3104@2|Bacteria,1P6K2@1224|Proteobacteria	1224|Proteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_3757694_7	344747.PM8797T_25596	7.102e-08	63.0	COG3137@1|root,COG3137@2|Bacteria,2J024@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
DTH1_k127_3757694_3	700598.Niako_1749	6.094e-61	219.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
DTH1_k127_3757694_6	293613.A1E_02110	1.825e-11	74.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,47EYI@766|Rickettsiales	766|Rickettsiales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH1_k127_3757694_1	497964.CfE428DRAFT_4660	6.321e-178	569.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_3757694_5	1121957.ATVL01000014_gene1459	1.005e-11	70.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3757694_8	740709.A10D4_00975	1.226e-05	51.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
DTH1_k127_3770310_2	481448.Minf_1864	2.178e-68	237.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,37FYY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
DTH1_k127_3770310_4	32057.KB217478_gene5529	1.289e-12	73.0	COG0858@1|root,COG0858@2|Bacteria,1G6JJ@1117|Cyanobacteria,1HNRI@1161|Nostocales	1117|Cyanobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
DTH1_k127_3770310_1	497964.CfE428DRAFT_1792	8.771e-69	245.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH1_k127_3770310_0	452637.Oter_2817	1.1e-79	272.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,3K75I@414999|Opitutae	414999|Opitutae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
DTH1_k127_3770310_3	1396418.BATQ01000085_gene1110	2.652e-66	239.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
DTH1_k127_3770310_5	1191523.MROS_0400	1.073e-08	60.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH1_k127_3771286_0	1226994.AMZB01000119_gene3308	6.335e-116	393.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria,1YD63@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_3771286_1	1089550.ATTH01000001_gene2299	9.049e-73	253.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
DTH1_k127_3771286_2	368407.Memar_0224	1.304e-08	59.0	COG2768@1|root,arCOG02448@2157|Archaea,2XW30@28890|Euryarchaeota,2N9AE@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
DTH1_k127_3780778_0	497964.CfE428DRAFT_2414	1.709e-97	334.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DTH1_k127_3780778_1	118166.JH976537_gene2419	1.035e-52	190.0	28NY3@1|root,2ZBVC@2|Bacteria,1G5MR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3780840_0	521674.Plim_4045	3.3e-40	174.0	2CGJ6@1|root,31UKG@2|Bacteria,2J1GT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3780840_1	935557.ATYB01000008_gene5010	2.053e-33	132.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,4B8TC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
DTH1_k127_3791304_3	365046.Rta_17060	8.035e-20	102.0	COG4447@1|root,COG4447@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3791304_0	478741.JAFS01000002_gene564	1.957e-166	533.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,37GDA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DTH1_k127_3791304_2	1201288.M900_A0014	6.502e-77	261.0	COG1838@1|root,COG1838@2|Bacteria,1R33Y@1224|Proteobacteria,43DIX@68525|delta/epsilon subdivisions,2MUNI@213481|Bdellovibrionales,2WK6Z@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
DTH1_k127_3791304_1	247490.KSU1_B0100	1.413e-149	483.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
DTH1_k127_3791354_4	324057.Pjdr2_0886	7.555e-57	209.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
DTH1_k127_3791354_0	452637.Oter_1389	6.206e-165	547.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_3791354_5	452637.Oter_2422	1.725e-56	204.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH1_k127_3791354_1	452637.Oter_0016	3.658e-108	369.0	COG0530@1|root,COG0530@2|Bacteria,46Y13@74201|Verrucomicrobia,3K8RV@414999|Opitutae	414999|Opitutae	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DTH1_k127_3791354_7	583355.Caka_0236	1.457e-25	111.0	2A5NK@1|root,30UDC@2|Bacteria,46YMP@74201|Verrucomicrobia,3K9UM@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3791354_9	28444.JODQ01000003_gene4977	2.289e-07	62.0	COG2324@1|root,COG2324@2|Bacteria,2IIUJ@201174|Actinobacteria,4EIUK@85012|Streptosporangiales	201174|Actinobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
DTH1_k127_3791354_3	696281.Desru_1739	2.908e-104	353.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
DTH1_k127_3791354_8	497964.CfE428DRAFT_0673	5.115e-23	112.0	COG1253@1|root,COG1253@2|Bacteria,46W8Q@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	DUF21
DTH1_k127_3791354_6	525904.Tter_0015	1.986e-51	205.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
DTH1_k127_3791354_2	497964.CfE428DRAFT_4760	9.334e-105	344.0	COG1082@1|root,COG1082@2|Bacteria,46SWE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_37982_1	1268240.ATFI01000001_gene3102	1.208e-22	103.0	COG0673@1|root,COG0673@2|Bacteria,4NFFJ@976|Bacteroidetes,2FQ50@200643|Bacteroidia,4AMH5@815|Bacteroidaceae	976|Bacteroidetes	S	Tat pathway signal sequence domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_37982_0	243090.RB8979	1.53e-179	576.0	COG1760@1|root,COG1760@2|Bacteria	2|Bacteria	E	l-serine dehydratase	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
DTH1_k127_3798543_1	452637.Oter_3509	1.228e-105	357.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_3798543_0	452637.Oter_2356	1.964e-112	373.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,3K7U5@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DTH1_k127_3798543_2	1396141.BATP01000003_gene5267	3.733e-66	229.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
DTH1_k127_3798543_3	497964.CfE428DRAFT_4165	2.982e-56	200.0	COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
DTH1_k127_3798543_4	309801.trd_1022	3.444e-37	153.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi,27YBG@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
DTH1_k127_3798543_5	1499967.BAYZ01000195_gene3085	3.554e-29	124.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH1_k127_3799497_4	1396141.BATP01000024_gene849	2.88e-06	49.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
DTH1_k127_3799497_0	1396141.BATP01000024_gene848	8.779e-166	539.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
DTH1_k127_3799497_3	1385515.N791_00065	1.004e-11	77.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria,1X406@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH1_k127_3799497_2	1396141.BATP01000024_gene851	6.181e-19	90.0	2EM29@1|root,33ERR@2|Bacteria,46WJK@74201|Verrucomicrobia,2IWEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3799497_1	886293.Sinac_6493	2.085e-95	327.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH1_k127_3803412_0	156889.Mmc1_2179	4.441e-09	70.0	COG1357@1|root,COG2931@1|root,COG3184@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3184@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Collar,HemolysinCabind,Peptidase_M10_C
DTH1_k127_3804498_3	479434.Sthe_2210	5.752e-55	201.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27XZ7@189775|Thermomicrobia	200795|Chloroflexi	E	TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DTH1_k127_3804498_1	1232410.KI421415_gene3062	1.871e-103	345.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,43U74@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH1_k127_3804498_0	880070.Cycma_3617	6.937e-129	434.0	2DBT1@1|root,2ZAV2@2|Bacteria,4NK57@976|Bacteroidetes,47XPG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3804498_2	497964.CfE428DRAFT_2622	2.897e-93	311.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DTH1_k127_3808913_2	314230.DSM3645_20627	2.311e-39	151.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_3808913_1	497964.CfE428DRAFT_0022	1.551e-80	275.0	COG0217@1|root,COG0217@2|Bacteria,46SMV@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DTH1_k127_3808913_0	240016.ABIZ01000001_gene4136	4.354e-286	894.0	COG2010@1|root,COG3241@1|root,COG2010@2|Bacteria,COG3241@2|Bacteria	2|Bacteria	C	Transfers electrons from cytochrome c551 to cytochrome oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
DTH1_k127_3817827_2	663610.JQKO01000019_gene3046	3.511e-21	110.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
DTH1_k127_3817827_0	509191.AEDB02000002_gene1137	5.035e-96	349.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH1_k127_3817827_1	663610.JQKO01000019_gene3046	1.385e-24	115.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
DTH1_k127_3820921_2	1142394.PSMK_15610	8.178e-14	82.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH1_k127_3820921_1	313628.LNTAR_13872	1.845e-20	102.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DTH1_k127_3820921_0	41431.PCC8801_4418	4.116e-71	253.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,3KFP8@43988|Cyanothece	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
DTH1_k127_3820921_4	530564.Psta_1300	1.422e-06	61.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,CW_binding_2,Calx-beta,HemolysinCabind,LTD,Metallophos,Peptidase_S8
DTH1_k127_3820921_3	243090.RB5356	2.82e-13	76.0	COG4968@1|root,COG4968@2|Bacteria,2J4ZS@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_3824786_3	497964.CfE428DRAFT_0567	2.62e-31	124.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DTH1_k127_3824786_0	478741.JAFS01000002_gene722	1.452e-120	400.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,37G1T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DTH1_k127_3824786_2	1396141.BATP01000027_gene1118	1.643e-32	129.0	COG0776@1|root,COG0776@2|Bacteria,46T4V@74201|Verrucomicrobia,2IUR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
DTH1_k127_3824786_1	1267533.KB906741_gene521	7.57e-120	392.0	COG0008@1|root,COG0008@2|Bacteria,3Y4TS@57723|Acidobacteria,2JKAU@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH1_k127_3850437_2	869213.JCM21142_93751	2.081e-49	183.0	COG2273@1|root,COG2273@2|Bacteria,4P0F6@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH1_k127_3850437_1	1123278.KB893597_gene2721	2.588e-125	423.0	COG1621@1|root,COG1621@2|Bacteria,4NJ8X@976|Bacteroidetes,47N6D@768503|Cytophagia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
DTH1_k127_3850437_0	240016.ABIZ01000001_gene5569	1.984e-138	462.0	COG1053@1|root,COG1053@2|Bacteria,46S51@74201|Verrucomicrobia,2IVH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH1_k127_3853550_1	616991.JPOO01000003_gene29	5.124e-100	341.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH1_k127_3853550_0	1267533.KB906739_gene2717	3.91e-231	737.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid_C,Bgal_small_N,Glyco_hydro_2,Glyco_hydro_28,Glyco_hydro_2_C,Glyco_hydro_2_N,fn3
DTH1_k127_3863373_3	452637.Oter_0712	6.438e-23	106.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
DTH1_k127_3863373_4	886293.Sinac_0920	4.106e-14	78.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_3863373_0	118166.JH976538_gene5057	4.576e-92	327.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
DTH1_k127_3863373_1	497964.CfE428DRAFT_2060	7.402e-75	263.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH1_k127_3863373_2	240016.ABIZ01000001_gene3616	1.769e-59	214.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_3864211_0	1303518.CCALI_02393	1.159e-53	205.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
DTH1_k127_3864211_1	402777.KB235904_gene3508	8.311e-10	70.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1H8BH@1150|Oscillatoriales	1117|Cyanobacteria	CT	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
DTH1_k127_3864211_2	81824.XP_001744199.1	6.34e-08	58.0	292VX@1|root,2R9SM@2759|Eukaryota	2759|Eukaryota	S	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
DTH1_k127_3873036_1	589865.DaAHT2_2431	2.85e-56	200.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MPFP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
DTH1_k127_3873036_0	237609.PSAKL28_31720	2.478e-279	880.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,1RZMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH1_k127_3873036_2	497964.CfE428DRAFT_1385	4.441e-29	119.0	COG3344@1|root,COG3344@2|Bacteria,46SUD@74201|Verrucomicrobia	2|Bacteria	L	Group II intron maturase-specific domain protein	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
DTH1_k127_387492_2	1121440.AUMA01000008_gene860	2.171e-49	186.0	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria,42VFT@68525|delta/epsilon subdivisions,2WRGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH1_k127_387492_1	497964.CfE428DRAFT_5265	2.38e-80	282.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_387492_0	661478.OP10G_3197	1.476e-102	350.0	28MB8@1|root,2ZAPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3881898_3	870187.Thini_4435	2.875e-05	55.0	28XJT@1|root,2ZJGX@2|Bacteria,1P89B@1224|Proteobacteria,1SWA4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3881898_2	794903.OPIT5_03260	3.837e-22	108.0	COG4783@1|root,COG4783@2|Bacteria,46TAI@74201|Verrucomicrobia,3K7ZQ@414999|Opitutae	414999|Opitutae	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3881898_0	497964.CfE428DRAFT_1756	4.36e-72	257.0	COG2207@1|root,COG2207@2|Bacteria,46T4M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, arabinose operon control protein	araC	-	-	-	-	-	-	-	-	-	-	-	HTH_18
DTH1_k127_3881898_1	497964.CfE428DRAFT_2397	2.549e-27	113.0	COG1858@1|root,COG1858@2|Bacteria,46SJU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem cytochrome c peroxidase	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
DTH1_k127_3882617_2	349741.Amuc_1436	2.716e-82	277.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH1_k127_3882617_0	1210884.HG799467_gene13206	2.95e-171	547.0	COG0205@1|root,COG0205@2|Bacteria,2IXXF@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DTH1_k127_3882617_3	1121324.CLIT_23c01830	1.86e-40	158.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH1_k127_3882617_1	497964.CfE428DRAFT_5019	2.612e-117	388.0	COG0077@1|root,COG0077@2|Bacteria,46U8V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
DTH1_k127_388613_2	1237149.C900_04129	6.238e-14	85.0	COG2911@1|root,COG3469@1|root,COG3979@1|root,COG2911@2|Bacteria,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
DTH1_k127_388613_1	1042376.AFPK01000062_gene1333	1.482e-99	349.0	COG2503@1|root,COG2503@2|Bacteria,4PN2E@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_388613_3	1303518.CCALI_02394	1.044e-06	56.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_388613_0	1396418.BATQ01000185_gene2115	2.903e-112	381.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
DTH1_k127_3890386_1	1121438.JNJA01000001_gene2267	1.22e-163	528.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
DTH1_k127_3890386_3	497964.CfE428DRAFT_1901	4.068e-29	119.0	COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH1_k127_3890386_0	349741.Amuc_1327	2.354e-166	532.0	COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,2ITS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH1_k127_3890386_2	1192868.CAIU01000002_gene149	5.391e-31	126.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,43JB7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
DTH1_k127_389120_0	1229780.BN381_640005	5.343e-118	407.0	29GCA@1|root,303A5@2|Bacteria,2H1W0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3898563_3	497964.CfE428DRAFT_2622	4.152e-55	195.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DTH1_k127_3898563_1	1122149.BACN01000037_gene1000	3.565e-66	238.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH1_k127_3898563_4	498761.HM1_0137	5.787e-27	129.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
DTH1_k127_3898563_0	886293.Sinac_4934	1.069e-70	271.0	COG3420@1|root,COG3420@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3898563_5	661367.LLO_1892	2.782e-25	124.0	COG3250@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Malectin,fn3
DTH1_k127_3898563_2	1232410.KI421425_gene1538	2.7e-64	230.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
DTH1_k127_3898635_3	411477.PARMER_01862	1.14e-28	117.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,2FNDG@200643|Bacteroidia,22X4T@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DTH1_k127_3898635_0	497964.CfE428DRAFT_0418	1.851e-80	279.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DTH1_k127_3898635_2	497964.CfE428DRAFT_5674	6.588e-50	186.0	COG0586@1|root,COG0586@2|Bacteria,46SWW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH1_k127_3898635_1	452637.Oter_0887	2.547e-50	196.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3899561_0	1210884.HG799466_gene12517	2.456e-14	81.0	COG4968@1|root,COG4968@2|Bacteria,2J4X1@203682|Planctomycetes	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_3912313_2	240016.ABIZ01000001_gene4784	6.39e-38	145.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,2IU02@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DTH1_k127_3912313_1	1396418.BATQ01000167_gene1768	3.193e-65	228.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH1_k127_3912313_0	1123070.KB899248_gene182	1.309e-81	274.0	COG0377@1|root,COG0377@2|Bacteria,46SMM@74201|Verrucomicrobia,2ITJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH1_k127_3914161_0	404589.Anae109_2915	6.706e-59	210.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3914161_5	983544.Lacal_2171	0.0009364	50.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I70K@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
DTH1_k127_3914161_1	452637.Oter_2699	5.549e-37	145.0	COG4430@1|root,COG4430@2|Bacteria,46WQC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
DTH1_k127_3914161_2	1122919.KB905557_gene1198	3.243e-17	87.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,26QK1@186822|Paenibacillaceae	91061|Bacilli	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH1_k127_3914161_3	1235803.C825_03137	1.646e-07	54.0	COG3547@1|root,COG3547@2|Bacteria,4PB8R@976|Bacteroidetes,2FYNJ@200643|Bacteroidia	976|Bacteroidetes	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3914161_4	1216976.AX27061_1104	1.522e-06	51.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VKHY@28216|Betaproteobacteria,3T90F@506|Alcaligenaceae	28216|Betaproteobacteria	LV	Retron-type reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
DTH1_k127_3926131_0	1396141.BATP01000006_gene5477	8.941e-241	762.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,46TDA@74201|Verrucomicrobia,2IV8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH1_k127_3932656_4	497964.CfE428DRAFT_3286	9.58e-06	53.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3932656_0	1156937.MFUM_920003	2.874e-145	473.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,37GCZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH1_k127_3932656_2	452637.Oter_2441	1.975e-60	217.0	COG0284@1|root,COG0284@2|Bacteria,46T17@74201|Verrucomicrobia,3K7VT@414999|Opitutae	414999|Opitutae	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DTH1_k127_3932656_1	240016.ABIZ01000001_gene2328	4.389e-124	410.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DTH1_k127_3932656_3	1267535.KB906767_gene933	7.626e-34	133.0	COG3669@1|root,COG3669@2|Bacteria,3Y37T@57723|Acidobacteria,2JKVF@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH1_k127_3938415_2	313624.NSP_15730	2.404e-23	104.0	COG2319@1|root,COG2319@2|Bacteria,1G0XZ@1117|Cyanobacteria,1HMMY@1161|Nostocales	1117|Cyanobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2,WD40
DTH1_k127_3938415_1	203124.Tery_0657	4.638e-28	132.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
DTH1_k127_3938415_0	1192034.CAP_0893	9.47e-59	231.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
DTH1_k127_3943954_4	164757.Mjls_1689	7.641e-09	63.0	COG3583@1|root,COG3666@1|root,COG3583@2|Bacteria,COG3666@2|Bacteria,2H4RU@201174|Actinobacteria,235V0@1762|Mycobacteriaceae	201174|Actinobacteria	L	Resuscitation-promoting factor rpfB	rpfB	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
DTH1_k127_3943954_1	483219.LILAB_30160	2.045e-154	497.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
DTH1_k127_3943954_0	497964.CfE428DRAFT_4597	3.24e-231	726.0	COG4108@1|root,COG4108@2|Bacteria,46SF9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
DTH1_k127_3943954_2	62928.azo2300	9.391e-139	452.0	COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,2VH3A@28216|Betaproteobacteria,2KVZG@206389|Rhodocyclales	206389|Rhodocyclales	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
DTH1_k127_3943954_3	756272.Plabr_3165	1.622e-66	229.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_396680_0	314230.DSM3645_04800	1.143e-85	307.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
DTH1_k127_3966826_0	1396141.BATP01000006_gene5432	1.663e-179	599.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH1_k127_3968615_1	118166.JH976538_gene5065	4.567e-63	238.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
DTH1_k127_3968615_0	452637.Oter_1700	3.397e-65	229.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_3970860_1	1403819.BATR01000184_gene6352	2.7e-92	309.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DTH1_k127_3970860_3	497964.CfE428DRAFT_4834	3.792e-59	216.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DTH1_k127_3970860_0	1396418.BATQ01000139_gene3250	9.547e-140	454.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,2ITI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
DTH1_k127_3970860_2	452637.Oter_4633	1.095e-72	263.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,3K73Q@414999|Opitutae	414999|Opitutae	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
DTH1_k127_3970860_4	497964.CfE428DRAFT_4831	1.228e-29	119.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
DTH1_k127_3978732_0	1454004.AW11_02080	0.0	1356.0	COG0166@1|root,COG0166@2|Bacteria,1PQU4@1224|Proteobacteria,2VKX3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the GPI family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_3978732_1	1496688.ER33_11555	1.224e-60	214.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
DTH1_k127_3994958_1	314230.DSM3645_26609	1.167e-53	196.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
DTH1_k127_3994958_0	452637.Oter_1501	2.552e-98	342.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
DTH1_k127_4006560_1	1403819.BATR01000191_gene6501	4.584e-44	166.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
DTH1_k127_4006560_0	1288963.ADIS_0485	1.055e-176	569.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_4021443_0	452637.Oter_2954	6.704e-295	921.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4021443_1	324057.Pjdr2_2563	7.628e-09	70.0	COG4447@1|root,COG4733@1|root,COG5297@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	dex	-	3.2.1.11	ko:K05988,ko:K06882	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	fn3
DTH1_k127_4021443_2	1403819.BATR01000069_gene2031	9.871e-06	59.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4024936_0	886293.Sinac_0949	3.454e-232	733.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
DTH1_k127_4024936_1	1396141.BATP01000030_gene3773	2.39e-184	589.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
DTH1_k127_4037212_1	1396141.BATP01000017_gene2771	1.176e-81	277.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia,2ITSD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DTH1_k127_4037212_0	382464.ABSI01000002_gene4277	1.514e-140	455.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,2ITV8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DTH1_k127_4037212_3	382464.ABSI01000013_gene1727	5.877e-57	207.0	COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia	74201|Verrucomicrobia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM
DTH1_k127_4037212_2	240016.ABIZ01000001_gene621	4.404e-64	236.0	COG4714@1|root,COG4714@2|Bacteria,46WYQ@74201|Verrucomicrobia,2IUN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
DTH1_k127_4037212_4	1192034.CAP_8221	1.608e-18	91.0	2C9T2@1|root,347D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4058911_10	1191523.MROS_2035	1.545e-49	180.0	COG0606@1|root,COG0606@2|Bacteria	2|Bacteria	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH1_k127_4058911_9	497964.CfE428DRAFT_6475	4.219e-58	211.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia	2|Bacteria	G	Domain of Unknown Function (DUF1080)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C
DTH1_k127_4058911_2	1396141.BATP01000060_gene4642	2.34e-124	408.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DTH1_k127_4058911_3	756499.Desde_3002	4.27e-103	348.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH1_k127_4058911_6	452637.Oter_0382	4.896e-85	287.0	COG2041@1|root,COG2041@2|Bacteria,46TCM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
DTH1_k127_4058911_8	1123508.JH636443_gene4582	5.391e-65	236.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH1_k127_4058911_7	1384056.N787_01780	1.354e-68	239.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4058911_4	1173028.ANKO01000017_gene232	2.522e-89	312.0	COG0378@1|root,COG0378@2|Bacteria,1G2X6@1117|Cyanobacteria,1H8P3@1150|Oscillatoriales	1117|Cyanobacteria	KO	Ni2 binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
DTH1_k127_4058911_11	65093.PCC7418_1276	3.992e-31	126.0	COG0375@1|root,COG0375@2|Bacteria,1G89Y@1117|Cyanobacteria	1117|Cyanobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
DTH1_k127_4058911_0	272134.KB731324_gene5867	7.605e-261	827.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
DTH1_k127_4058911_12	518766.Rmar_2594	1.395e-27	113.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes	976|Bacteroidetes	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
DTH1_k127_4058911_1	204669.Acid345_1705	1.022e-177	566.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia	204432|Acidobacteriia	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
DTH1_k127_4058911_5	56110.Oscil6304_5908	1.192e-87	294.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1H82T@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DTH1_k127_4063852_3	1120944.JONS01000015_gene2423	4.013e-15	86.0	COG0463@1|root,COG0463@2|Bacteria,2GT8V@201174|Actinobacteria,4D7WR@85005|Actinomycetales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH1_k127_4063852_5	481448.Minf_0708	5.983e-05	53.0	COG2242@1|root,COG2242@2|Bacteria,46WJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH1_k127_4063852_2	497964.CfE428DRAFT_1387	3.445e-38	158.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH1_k127_4063852_0	497964.CfE428DRAFT_6143	3.106e-62	221.0	COG0163@1|root,COG0163@2|Bacteria,46V9E@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DTH1_k127_4063852_1	984262.SGRA_1441	1.284e-59	218.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH1_k127_406956_0	926569.ANT_29620	2.354e-130	430.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DTH1_k127_406956_2	765912.Thimo_3050	1.45e-94	318.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
DTH1_k127_406956_4	504728.K649_06595	5.752e-63	226.0	COG3257@1|root,COG3257@2|Bacteria,1WJWA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein possibly involved in glyoxylate utilization	-	-	3.5.3.26	ko:K14977	ko00230,ko01120,map00230,map01120	-	R05554	RC01419	ko00000,ko00001,ko01000	-	-	-	Cupin_2
DTH1_k127_406956_1	391625.PPSIR1_08312	1.139e-125	435.0	COG5434@1|root,COG5434@2|Bacteria,1RJPM@1224|Proteobacteria,42T21@68525|delta/epsilon subdivisions,2WPCS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_406956_5	1396141.BATP01000045_gene1848	1.966e-08	68.0	COG2911@1|root,COG3866@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG3866@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH1_k127_406956_3	314230.DSM3645_10162	5.234e-87	297.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH1_k127_4076703_0	1267535.KB906767_gene2459	2.797e-53	196.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,DUF4832,DUF4978,FIVAR,Glyco_hydro_42,Glyco_hydro_42M
DTH1_k127_4076703_1	1121272.KB903251_gene659	0.000541	51.0	COG3866@1|root,COG4733@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria,2GNKW@201174|Actinobacteria,4DAGW@85008|Micromonosporales	201174|Actinobacteria	G	Amb_all	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	DUF1080,Pec_lyase_C
DTH1_k127_4080255_2	521674.Plim_2802	1.893e-11	63.0	COG0673@1|root,COG0673@2|Bacteria,2IXUF@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_4080255_1	1396418.BATQ01000117_gene4568	2.169e-231	727.0	COG0738@1|root,COG0738@2|Bacteria,46U7F@74201|Verrucomicrobia,2IUMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_4080255_0	497964.CfE428DRAFT_0141	1.991e-297	937.0	COG1082@1|root,COG4993@1|root,COG1082@2|Bacteria,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
DTH1_k127_4092124_3	246197.MXAN_0623	4.194e-40	159.0	COG3428@1|root,COG3428@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
DTH1_k127_4092124_1	452637.Oter_0623	2.064e-55	199.0	COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
DTH1_k127_4092124_6	935863.AWZR01000007_gene245	2.068e-11	67.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales	135614|Xanthomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH1_k127_4092124_4	383372.Rcas_0336	5.561e-25	122.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
DTH1_k127_4092124_7	1120949.KB903306_gene7572	1.103e-05	59.0	COG1361@1|root,COG2304@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,2I8F1@201174|Actinobacteria,4DFBB@85008|Micromonosporales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3344
DTH1_k127_4092124_5	794903.OPIT5_07325	1.499e-18	92.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH1_k127_4092124_2	926560.KE387023_gene2150	7.223e-47	196.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2
DTH1_k127_4092124_0	1121920.AUAU01000009_gene1881	1.733e-66	260.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH1_k127_4092124_8	400682.PAC_15716390	0.0004911	54.0	2DZK8@1|root,2S73K@2759|Eukaryota,3AA3U@33154|Opisthokonta,3BU2C@33208|Metazoa	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_4095154_1	234267.Acid_6968	5.897e-45	167.0	COG5012@1|root,COG5012@2|Bacteria,3Y88D@57723|Acidobacteria	57723|Acidobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
DTH1_k127_4095154_3	278957.ABEA03000093_gene4635	7.387e-20	94.0	arCOG03330@1|root,2Z82Q@2|Bacteria	2|Bacteria	S	PFAM Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
DTH1_k127_4095154_0	1123242.JH636435_gene1092	2.368e-179	572.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_4095154_2	519989.ECTPHS_02009	4.388e-43	162.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DTH1_k127_410022_1	1382356.JQMP01000003_gene1715	3.841e-21	97.0	COG0684@1|root,COG0684@2|Bacteria,2GBDU@200795|Chloroflexi,27Z0W@189775|Thermomicrobia	189775|Thermomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DTH1_k127_410022_3	1121445.ATUZ01000020_gene2153	0.000111	51.0	COG2755@1|root,COG2755@2|Bacteria,1P2JM@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_410022_2	1151117.AJLF01000001_gene1466	1.329e-12	79.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
DTH1_k127_410022_0	56780.SYN_02389	8.855e-99	336.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH1_k127_4101218_1	351348.Maqu_4129	1.805e-78	273.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,4679W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
DTH1_k127_4101218_0	1117958.PE143B_0105790	2.318e-165	535.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
DTH1_k127_4103474_3	1123242.JH636435_gene772	1.719e-28	115.0	COG0477@1|root,COG2814@2|Bacteria,2J4VW@203682|Planctomycetes	1123242.JH636435_gene772|-	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4103474_0	1123242.JH636434_gene3154	4.862e-126	413.0	COG2159@1|root,COG2159@2|Bacteria,2J3RZ@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH1_k127_4103474_1	861299.J421_5653	9.316e-114	389.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_4103474_2	1123242.JH636435_gene769	6.486e-73	259.0	2DBNR@1|root,2ZA54@2|Bacteria,2IYX9@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
DTH1_k127_4118232_5	583355.Caka_1736	6.454e-34	145.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_4118232_6	56780.SYN_01800	1.271e-31	134.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH1_k127_4118232_2	314230.DSM3645_06659	2.411e-73	265.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
DTH1_k127_4118232_3	543728.Vapar_4986	9.236e-66	238.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria,2VKVF@28216|Betaproteobacteria,4AFFZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315,2.4.1.46	ko:K03429,ko:K03715	ko00561,ko01100,map00561,map01100	-	R02689,R02691,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
DTH1_k127_4118232_0	886293.Sinac_0656	1.385e-239	754.0	COG1053@1|root,COG1053@2|Bacteria,2IYNS@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH1_k127_4118232_7	977880.RALTA_A2916	2.352e-22	100.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,1KHET@119060|Burkholderiaceae	28216|Betaproteobacteria	P	tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DTH1_k127_4118232_4	215803.DB30_3302	2.678e-38	151.0	2F6YT@1|root,33ZET@2|Bacteria,1Q2TV@1224|Proteobacteria,438FU@68525|delta/epsilon subdivisions,2X3QS@28221|Deltaproteobacteria,2YWVH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4118232_1	497964.CfE428DRAFT_1508	7.538e-128	419.0	COG1620@1|root,COG1620@2|Bacteria,46UQW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	L-lactate permease	-	-	-	-	-	-	-	-	-	-	-	-	Lactate_perm
DTH1_k127_4121821_3	258594.RPA3342	8.38e-51	187.0	COG3693@1|root,COG3693@2|Bacteria,1QXZM@1224|Proteobacteria,2TXEV@28211|Alphaproteobacteria,3K6U7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
DTH1_k127_4121821_5	313590.MED134_04514	2.928e-15	88.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,37EHK@326319|Dokdonia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH1_k127_4121821_2	32057.KB217478_gene7545	3.069e-67	245.0	COG2730@1|root,COG2730@2|Bacteria,1G3EZ@1117|Cyanobacteria	1117|Cyanobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
DTH1_k127_4121821_0	861299.J421_5653	5.273e-127	422.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_4121821_1	1267535.KB906767_gene3448	1.474e-73	262.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Pectate_lyase_3
DTH1_k127_4121821_4	1122611.KB903963_gene4742	8.925e-37	151.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria,4EGCR@85012|Streptosporangiales	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
DTH1_k127_4121821_6	1122611.KB904012_gene6811	0.0002397	52.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria,4EK62@85012|Streptosporangiales	201174|Actinobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,Laminin_G_3,PT-HINT,RHS_repeat
DTH1_k127_4130022_5	452637.Oter_2330	8.72e-33	130.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
DTH1_k127_4130022_2	1267535.KB906767_gene1118	7.684e-69	243.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria,2JJIJ@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH1_k127_4130022_1	641524.ADICYQ_2355	1.916e-93	330.0	COG4403@1|root,COG4403@2|Bacteria,4PMC1@976|Bacteroidetes,47Y49@768503|Cytophagia	976|Bacteroidetes	V	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH1_k127_4130022_3	1156937.MFUM_920008	6.231e-48	175.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,37GI8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
DTH1_k127_4130022_4	240016.ABIZ01000001_gene908	1.968e-40	165.0	COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DTH1_k127_4130022_6	478741.JAFS01000002_gene252	1.473e-13	77.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,37GXU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	STAS domain	rsbS	-	-	-	-	-	-	-	-	-	-	-	STAS
DTH1_k127_4130022_0	497964.CfE428DRAFT_3487	2.988e-138	478.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
DTH1_k127_4141705_6	595460.RRSWK_05050	7.411e-06	49.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH1_k127_4141705_2	1303518.CCALI_00532	1.936e-161	518.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
DTH1_k127_4141705_0	886293.Sinac_5668	1.876e-219	688.0	COG2115@1|root,COG2115@2|Bacteria,2IWUS@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH1_k127_4141705_3	497964.CfE428DRAFT_0773	2.577e-100	336.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH1_k127_4141705_4	86416.Clopa_2098	3.722e-24	110.0	2A1FW@1|root,30PPA@2|Bacteria,1UA53@1239|Firmicutes,254CY@186801|Clostridia,36TYS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4141705_5	497964.CfE428DRAFT_0773	3.169e-14	75.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH1_k127_4141705_1	1210884.HG799465_gene11752	7.433e-188	602.0	COG1012@1|root,COG1012@2|Bacteria,2IYRE@203682|Planctomycetes	203682|Planctomycetes	C	ketoglutarate semialdehyde dehydrogenase	-	-	1.2.1.4	ko:K14519	ko00930,ko01100,ko01120,ko01220,map00930,map01100,map01120,map01220	-	R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
DTH1_k127_4151367_3	497964.CfE428DRAFT_3787	1.067e-06	61.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4151367_1	478741.JAFS01000001_gene1574	4.317e-55	203.0	COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia,37G0D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH1_k127_4151367_2	497964.CfE428DRAFT_1105	6.564e-43	173.0	COG1427@1|root,COG1427@2|Bacteria,46VTU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH1_k127_4151367_0	1125863.JAFN01000001_gene1137	1.715e-74	259.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42TJM@68525|delta/epsilon subdivisions,2WQGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DTH1_k127_4152953_0	1267533.KB906733_gene3043	2.097e-180	580.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria,2JIRH@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH1_k127_4152953_1	1123227.KB899339_gene1445	2.898e-27	118.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
DTH1_k127_4158294_1	1396141.BATP01000003_gene5168	2.543e-136	451.0	2EKQJ@1|root,33EEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4158294_0	1132441.KI519454_gene1142	4.805e-267	846.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4158294_2	273068.TTE2349	3.153e-88	308.0	COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,249YD@186801|Clostridia,42HSQ@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
DTH1_k127_416647_0	497964.CfE428DRAFT_6644	5.5e-241	763.0	COG1657@1|root,COG1657@2|Bacteria,46TK5@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	sqhC	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
DTH1_k127_416647_1	338966.Ppro_2630	2.21e-45	173.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DTH1_k127_4177096_2	379066.GAU_1612	7.242e-60	214.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH1_k127_4177096_4	693977.Deipr_0877	0.0002902	51.0	COG4700@1|root,COG4700@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	GerE,PLDc_N,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
DTH1_k127_4177096_0	497964.CfE428DRAFT_2485	2.92e-185	587.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4177096_1	562970.Btus_1769	5.694e-109	370.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
DTH1_k127_4177096_3	497964.CfE428DRAFT_2523	1.057e-15	79.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
DTH1_k127_4177588_0	1396418.BATQ01000120_gene3087	2.07e-17	97.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH1_k127_4177588_2	794903.OPIT5_22725	2.606e-09	69.0	COG2165@1|root,COG2165@2|Bacteria,46YHE@74201|Verrucomicrobia,3K9KI@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH1_k127_4177588_1	344747.PM8797T_04455	6.192e-14	81.0	COG2165@1|root,COG2165@2|Bacteria,2J1XE@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10
DTH1_k127_4177588_3	1396141.BATP01000019_gene1725	1.569e-07	59.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46WVI@74201|Verrucomicrobia,2IW5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH1_k127_4183331_0	861299.J421_1753	2.781e-133	447.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH1_k127_4183331_1	504472.Slin_3038	3.581e-116	393.0	COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,47K44@768503|Cytophagia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH1_k127_4183331_2	1303518.CCALI_01258	1.324e-06	58.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_41944_2	1288963.ADIS_1386	5.088e-76	268.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_41944_0	861299.J421_1753	9.439e-294	943.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH1_k127_41944_1	861299.J421_1753	9.606e-126	416.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH1_k127_4195548_2	1210884.HG799470_gene14459	5.44e-43	162.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
DTH1_k127_4195548_0	452637.Oter_3498	3.587e-135	439.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH1_k127_4195548_3	742742.HMPREF9452_01467	7.64e-21	99.0	COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DTH1_k127_4195548_1	497964.CfE428DRAFT_3924	7.857e-64	224.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DTH1_k127_4195548_4	1122135.KB893135_gene779	2.101e-07	55.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
DTH1_k127_4199783_0	497964.CfE428DRAFT_4932	2.666e-130	420.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH1_k127_4211362_0	1123073.KB899245_gene180	1.85e-66	238.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,1X595@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
DTH1_k127_4211362_2	583355.Caka_1868	7.605e-41	155.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,3K871@414999|Opitutae	414999|Opitutae	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
DTH1_k127_4211362_1	338963.Pcar_1829	9.683e-54	197.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,43TKK@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
DTH1_k127_4244623_1	497964.CfE428DRAFT_5731	5.169e-43	164.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_4244623_0	1396141.BATP01000057_gene2930	3.977e-118	413.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH1_k127_4251177_0	497964.CfE428DRAFT_2824	0.0	1658.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4251177_1	497964.CfE428DRAFT_2825	8.189e-124	402.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46TEF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Von Willebrand factor	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,VWA_3,vWF_A
DTH1_k127_4259988_0	497964.CfE428DRAFT_0339	3.027e-141	462.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
DTH1_k127_4259988_1	497964.CfE428DRAFT_1897	2.508e-88	304.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
DTH1_k127_4259988_3	717605.Theco_1040	1.484e-28	124.0	COG0128@1|root,COG0128@2|Bacteria,1VK19@1239|Firmicutes,4HQZ9@91061|Bacilli,26WZM@186822|Paenibacillaceae	91061|Bacilli	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4259988_2	309807.SRU_2566	3.395e-35	153.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1FJBA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
DTH1_k127_4259988_4	391587.KAOT1_16038	3.996e-15	81.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH1_k127_427198_1	497964.CfE428DRAFT_5288	3.26e-45	172.0	COG0811@1|root,COG0811@2|Bacteria,46V4I@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
DTH1_k127_427198_2	497964.CfE428DRAFT_5287	1.76e-21	99.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH1_k127_427198_3	1121456.ATVA01000013_gene1066	9.766e-05	53.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,42XAV@68525|delta/epsilon subdivisions,2WSJJ@28221|Deltaproteobacteria,2M7R0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
DTH1_k127_427198_0	404380.Gbem_3513	2.616e-49	192.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
DTH1_k127_4275719_2	794903.OPIT5_20565	8.299e-105	347.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,3K7IM@414999|Opitutae	414999|Opitutae	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH1_k127_4275719_7	1403819.BATR01000031_gene994	6.007e-07	57.0	2EMM1@1|root,33F9E@2|Bacteria,46TBT@74201|Verrucomicrobia,2IUX2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4275719_4	325452.fgenesh_scip_prom.46568.7654	3.228e-67	231.0	COG0318@1|root,COG0590@1|root,KOG1018@2759|Eukaryota,KOG1176@2759|Eukaryota,3Q9PC@4776|Peronosporales	4776|Peronosporales	I	AMP-binding enzyme C-terminal domain	-	-	-	ko:K18660	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
DTH1_k127_4275719_0	497964.CfE428DRAFT_6179	6.673e-171	561.0	COG3875@1|root,COG3875@2|Bacteria,46TVY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
DTH1_k127_4275719_3	768671.ThimaDRAFT_3418	2.054e-77	269.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WXRA@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH1_k127_4275719_1	497964.CfE428DRAFT_5037	3.561e-141	462.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
DTH1_k127_4275719_6	1120971.AUCA01000003_gene1386	8.614e-22	99.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,27A9H@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix gluconate operon transcriptional repressor	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
DTH1_k127_4275719_5	935839.JAGJ01000016_gene2387	6.869e-42	162.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4F45P@85017|Promicromonosporaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DTH1_k127_4282108_3	1219035.NT2_01_05550	2.578e-06	49.0	28J0M@1|root,2Z8XS@2|Bacteria,1RKDT@1224|Proteobacteria,2U9QW@28211|Alphaproteobacteria,2KA4X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4282108_2	794903.OPIT5_14770	6.939e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_4282108_1	661478.OP10G_1032	2.949e-45	188.0	COG4354@1|root,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
DTH1_k127_4282108_0	661478.OP10G_1031	7.034e-225	726.0	COG1621@1|root,COG4354@1|root,COG1621@2|Bacteria,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
DTH1_k127_4327181_6	497964.CfE428DRAFT_4379	1.275e-26	116.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH1_k127_4327181_7	497964.CfE428DRAFT_4380	4.136e-25	113.0	COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH1_k127_4327181_5	497964.CfE428DRAFT_3022	2.959e-35	138.0	COG2363@1|root,COG2363@2|Bacteria,46T86@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
DTH1_k127_4327181_10	497964.CfE428DRAFT_5963	5.293e-12	78.0	2F7AY@1|root,33ZS4@2|Bacteria,46VZW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4327181_8	1396141.BATP01000023_gene664	3.376e-18	99.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
DTH1_k127_4327181_0	452637.Oter_4549	2.639e-110	366.0	28JIN@1|root,30U02@2|Bacteria,46YTT@74201|Verrucomicrobia,3K7XH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4327181_1	382464.ABSI01000013_gene1636	7.292e-93	313.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DTH1_k127_4327181_4	525904.Tter_2300	4.556e-36	142.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
DTH1_k127_4327181_11	316274.Haur_4856	1.564e-11	79.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
DTH1_k127_4327181_9	661478.OP10G_4013	3.176e-15	86.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,T2SSG
DTH1_k127_4327181_2	880070.Cycma_0098	1.026e-64	239.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K02347,ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	PHP
DTH1_k127_4327181_3	1121012.AUKX01000034_gene615	3.67e-46	176.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,1I821@117743|Flavobacteriia,23FKJ@178469|Arenibacter	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH1_k127_4328472_5	240015.ACP_1472	6.76e-06	57.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria,2JHRN@204432|Acidobacteriia	204432|Acidobacteriia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH1_k127_4328472_2	99598.Cal7507_3402	1.77e-62	223.0	2EY4W@1|root,33RDQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4328472_1	99598.Cal7507_3403	2.282e-131	434.0	COG0754@1|root,COG0754@2|Bacteria	2|Bacteria	E	glutathionylspermidine amidase activity	gsp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464	3.5.1.78,6.3.1.8	ko:K01460	ko00480,ko01100,map00480,map01100	-	R01917,R01918	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3484	CHAP,GSP_synth
DTH1_k127_4328472_3	99598.Cal7507_3404	7.104e-52	193.0	2F1DQ@1|root,33UEG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4328472_4	1232410.KI421424_gene1610	4.592e-42	175.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
DTH1_k127_4328472_0	240016.ABIZ01000001_gene5947	1.721e-148	475.0	COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia,2ITXS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH1_k127_4341687_3	794903.OPIT5_08425	5.545e-06	57.0	COG4968@1|root,COG4968@2|Bacteria,46YJJ@74201|Verrucomicrobia,3K9QQ@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4341687_0	1396141.BATP01000007_gene5570	4.154e-116	409.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH1_k127_4341687_2	1303518.CCALI_02638	3.783e-11	74.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_4341687_1	886293.Sinac_6980	1.426e-91	303.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_4353902_0	1403819.BATR01000057_gene1772	3.794e-196	640.0	COG3474@1|root,COG3474@2|Bacteria,46TEP@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_4353902_1	521674.Plim_0111	6.966e-133	438.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_4397666_1	161156.JQKW01000008_gene436	1.183e-13	76.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K19093	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
DTH1_k127_4397666_0	1499967.BAYZ01000009_gene5298	1.701e-273	866.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
DTH1_k127_4401361_0	595460.RRSWK_04184	3.219e-150	493.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DTH1_k127_4403873_1	886293.Sinac_0185	4.134e-37	160.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
DTH1_k127_4403873_0	1210884.HG799476_gene15380	2.525e-58	226.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
DTH1_k127_441547_2	1385935.N836_16125	7.238e-84	284.0	COG5434@1|root,COG5434@2|Bacteria,1GC14@1117|Cyanobacteria,1HF7U@1150|Oscillatoriales	1117|Cyanobacteria	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
DTH1_k127_441547_3	530564.Psta_4257	6.06e-72	256.0	COG2755@1|root,COG5306@1|root,COG2755@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
DTH1_k127_441547_4	391735.Veis_0534	1.237e-07	65.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VJM2@28216|Betaproteobacteria,4A9PV@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH1_k127_441547_1	1123073.KB899241_gene3085	6.247e-123	425.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Big_2,Big_4,F5_F8_type_C,Glyco_hydro_16,Inhibitor_I9,PA,Peptidase_S8,SLH
DTH1_k127_441547_0	521674.Plim_3713	1.567e-248	775.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Glyco_hydro_28
DTH1_k127_4416299_5	768066.HELO_3427	6.777e-05	50.0	COG3339@1|root,COG3339@2|Bacteria,1N9BI@1224|Proteobacteria,1SC8Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
DTH1_k127_4416299_0	1070319.CAGGBEG34_190038	2.741e-110	375.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
DTH1_k127_4416299_3	330214.NIDE3682	1.799e-24	108.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
DTH1_k127_4416299_2	1280950.HJO_06350	1.38e-27	115.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,43XSM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
DTH1_k127_4416299_1	497964.CfE428DRAFT_6605	3.799e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DTH1_k127_4416299_4	334545.CCMG01000011_gene846	1.225e-21	95.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,47F1I@766|Rickettsiales	766|Rickettsiales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DTH1_k127_4427210_1	1379698.RBG1_1C00001G0109	7.825e-71	248.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
DTH1_k127_4427210_0	247490.KSU1_D0783	8.521e-86	297.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
DTH1_k127_4427210_2	247490.KSU1_D0782	3.214e-29	119.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4439581_1	497964.CfE428DRAFT_6252	2.813e-81	282.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DTH1_k127_4439581_0	471853.Bcav_3390	4.736e-132	444.0	COG2730@1|root,COG3537@1|root,COG4225@1|root,COG2730@2|Bacteria,COG3537@2|Bacteria,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,F5_F8_type_C,Hepar_II_III,Ricin_B_lectin
DTH1_k127_4439581_6	203119.Cthe_3006	0.0002602	51.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1V9XU@1239|Firmicutes,24NW6@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
DTH1_k127_4439581_2	945713.IALB_3143	3.158e-62	219.0	COG0229@1|root,COG0229@2|Bacteria	2|Bacteria	O	peptide-methionine (R)-S-oxide reductase activity	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DTH1_k127_4439581_4	756272.Plabr_3911	5.013e-22	106.0	COG4632@1|root,COG4632@2|Bacteria,2J149@203682|Planctomycetes	203682|Planctomycetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
DTH1_k127_4446506_2	926562.Oweho_2087	9.402e-28	114.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia,2PAXX@246874|Cryomorphaceae	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
DTH1_k127_4446506_0	1121930.AQXG01000002_gene2269	5.155e-161	520.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
DTH1_k127_4446506_3	1356852.N008_20380	4.096e-24	109.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
DTH1_k127_4446506_1	313606.M23134_03514	7.81e-52	191.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
DTH1_k127_4449745_0	1396141.BATP01000030_gene3715	6.458e-93	331.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH1_k127_4449745_1	485918.Cpin_7074	2.82e-37	162.0	COG3115@1|root,COG3115@2|Bacteria,4PN8V@976|Bacteroidetes,1J0PP@117747|Sphingobacteriia	976|Bacteroidetes	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4453499_0	497964.CfE428DRAFT_1603	9.47e-170	544.0	COG0673@1|root,COG0673@2|Bacteria,46TYR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_4453499_3	323261.Noc_1412	3.747e-58	209.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1X0Q2@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
DTH1_k127_4453499_2	530564.Psta_1556	2.811e-60	221.0	29525@1|root,2ZSEY@2|Bacteria,2IZ8U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4453499_4	497964.CfE428DRAFT_3900	4.251e-58	211.0	2AU2S@1|root,31JP5@2|Bacteria,46VDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_4453499_5	635013.TherJR_1860	4.712e-15	79.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DTH1_k127_4453499_1	498848.TaqDRAFT_4878	4.514e-65	237.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4498439_3	240016.ABIZ01000001_gene5629	4.253e-43	166.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	CP_0628	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2,VIT
DTH1_k127_4498439_0	526218.Sterm_4083	2.594e-103	351.0	COG5505@1|root,COG5505@2|Bacteria,37B8T@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
DTH1_k127_4498439_1	443143.GM18_3718	2.066e-93	316.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
DTH1_k127_4498439_2	497964.CfE428DRAFT_1669	5.111e-69	241.0	COG0563@1|root,COG0563@2|Bacteria,46SW4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
DTH1_k127_44996_6	861299.J421_5620	3.133e-18	88.0	28J3W@1|root,2Z900@2|Bacteria	2|Bacteria	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
DTH1_k127_44996_3	448385.sce3153	3.265e-90	302.0	COG0670@1|root,COG0670@2|Bacteria,1R7VN@1224|Proteobacteria,43DVQ@68525|delta/epsilon subdivisions,2WZ04@28221|Deltaproteobacteria,2Z11K@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
DTH1_k127_44996_8	94122.Shewana3_0285	2.452e-12	69.0	COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,1SGD5@1236|Gammaproteobacteria,2QCT8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
DTH1_k127_44996_1	278957.ABEA03000091_gene714	6.855e-111	365.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,3K7VW@414999|Opitutae	414999|Opitutae	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DTH1_k127_44996_0	1396418.BATQ01000078_gene592	1.648e-153	494.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia,2IWM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cobalamin-independent synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
DTH1_k127_44996_2	1185876.BN8_00813	2.48e-108	358.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
DTH1_k127_44996_10	682795.AciX8_1050	2.364e-06	59.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria,2JJP2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_44996_4	497964.CfE428DRAFT_1749	1.921e-46	171.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
DTH1_k127_44996_7	497964.CfE428DRAFT_3480	1.582e-13	78.0	2FHXR@1|root,349QR@2|Bacteria,46WDM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
DTH1_k127_44996_9	1173263.Syn7502_00565	1.554e-06	55.0	COG2104@1|root,COG2104@2|Bacteria,1G986@1117|Cyanobacteria	1117|Cyanobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
DTH1_k127_44996_5	589865.DaAHT2_0949	1.529e-18	89.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
DTH1_k127_4553455_10	240015.ACP_2565	6.53e-46	167.0	COG0838@1|root,COG0838@2|Bacteria,3Y8B8@57723|Acidobacteria,2JN67@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH1_k127_4553455_4	1267534.KB906754_gene3780	3.37e-103	338.0	COG0377@1|root,COG0377@2|Bacteria,3Y74G@57723|Acidobacteria,2JKT1@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH1_k127_4553455_5	1267534.KB906754_gene3779	1.88e-90	306.0	COG0852@1|root,COG0852@2|Bacteria,3Y72R@57723|Acidobacteria,2JM53@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH1_k127_4553455_0	1267534.KB906754_gene3778	8.662e-199	625.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DTH1_k127_4553455_3	1216966.BAUC01000035_gene3110	4.924e-104	357.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Glutamate synthase	gltD	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_3503,iYL1228.KPN_03625	Fer4_20,Pyr_redox_2
DTH1_k127_4553455_8	452637.Oter_0743	9.92e-52	186.0	COG0838@1|root,COG0838@2|Bacteria,46XVA@74201|Verrucomicrobia,3K8I9@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH1_k127_4553455_6	452637.Oter_0744	5.931e-90	298.0	COG0377@1|root,COG0377@2|Bacteria,46YVB@74201|Verrucomicrobia,3K85T@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH1_k127_4553455_7	452637.Oter_0745	1.229e-57	206.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH1_k127_4553455_1	452637.Oter_0746	7.986e-190	598.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K8K5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DTH1_k127_4553455_2	452637.Oter_0747	1.24e-152	488.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K82N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH1_k127_4553455_9	452637.Oter_0748	2.64e-50	193.0	COG1143@1|root,COG1143@2|Bacteria,46YB4@74201|Verrucomicrobia,3K98S@414999|Opitutae	414999|Opitutae	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
DTH1_k127_4553455_11	452637.Oter_0749	9.191e-43	162.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH1_k127_4553455_13	452637.Oter_0750	1.802e-36	141.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH1_k127_4553455_12	452637.Oter_0751	1.575e-39	151.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH1_k127_4562068_0	1121335.Clst_0783	5.09e-143	459.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
DTH1_k127_4562068_1	1123508.JH636442_gene3883	1.735e-21	108.0	COG3779@1|root,COG3779@2|Bacteria,2J1PD@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314
DTH1_k127_4603230_1	886293.Sinac_2421	1.665e-29	123.0	COG0673@1|root,COG0673@2|Bacteria,2IWZY@203682|Planctomycetes	203682|Planctomycetes	G	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_4603230_0	509191.AEDB02000022_gene2935	1.38e-113	390.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
DTH1_k127_4603230_2	1396141.BATP01000005_gene6014	1.079e-09	63.0	COG2312@1|root,COG4625@1|root,COG2312@2|Bacteria,COG4625@2|Bacteria,46WKK@74201|Verrucomicrobia,2IWCX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4646496_2	1403819.BATR01000135_gene4816	8.796e-249	775.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
DTH1_k127_4646496_3	234267.Acid_7032	2.146e-104	353.0	COG2271@1|root,COG2271@2|Bacteria,3Y3FW@57723|Acidobacteria	57723|Acidobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_4646496_1	886293.Sinac_7008	2.052e-252	784.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_4646496_0	497964.CfE428DRAFT_0238	0.0	1268.0	COG2010@1|root,COG2010@2|Bacteria,46TSG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_4650144_3	177437.HRM2_29480	0.0002138	50.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2WM9F@28221|Deltaproteobacteria,2MJ6C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
DTH1_k127_4650144_2	478741.JAFS01000002_gene111	1.018e-06	59.0	COG1196@1|root,COG1196@2|Bacteria,46Z83@74201|Verrucomicrobia,37GKF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4650144_0	986075.CathTA2_2568	1.165e-138	457.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli	91061|Bacilli	D	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DTH1_k127_4650144_1	1158338.JNLJ01000001_gene166	2.41e-17	83.0	COG0212@1|root,COG0212@2|Bacteria,2G47M@200783|Aquificae	200783|Aquificae	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
DTH1_k127_4673440_1	856793.MICA_129	7.876e-34	153.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Mfa_like_1,PQQ_2,RCC1,RCC1_2
DTH1_k127_4673440_0	99598.Cal7507_3395	5.004e-99	366.0	COG1520@1|root,COG1520@2|Bacteria,1GHEB@1117|Cyanobacteria,1HKIG@1161|Nostocales	1117|Cyanobacteria	C	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PPC
DTH1_k127_4673440_2	1380391.JIAS01000011_gene4618	2.04e-10	76.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2JWHH@204441|Rhodospirillales	204441|Rhodospirillales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
DTH1_k127_4689509_2	1122194.AUHU01000009_gene3274	2.953e-33	150.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,GDE_C
DTH1_k127_4689509_1	382464.ABSI01000010_gene3515	4.276e-41	166.0	2F006@1|root,33T46@2|Bacteria,46U4Y@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4692150_1	661478.OP10G_4802	2.433e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_4692150_0	1121346.KB899824_gene3032	9.354e-55	208.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
DTH1_k127_4693364_0	497964.CfE428DRAFT_3455	1.451e-45	173.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
DTH1_k127_4693364_1	1211813.CAPH01000017_gene773	2.809e-45	190.0	COG3408@1|root,COG3408@2|Bacteria,4P4HZ@976|Bacteroidetes	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4693364_2	1123276.KB893246_gene561	4.429e-08	67.0	COG2010@1|root,COG3345@1|root,COG4625@1|root,COG2010@2|Bacteria,COG3345@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
DTH1_k127_470456_0	1123242.JH636435_gene1022	1.252e-76	271.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
DTH1_k127_470456_1	886293.Sinac_6513	2.415e-10	73.0	291K2@1|root,2ZP6D@2|Bacteria,2IZ9X@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
DTH1_k127_4728943_3	189425.PGRAT_08230	2.051e-19	99.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,271NY@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_4728943_1	1303518.CCALI_02490	5.762e-83	285.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_4728943_0	382464.ABSI01000009_gene3917	1.169e-131	428.0	COG1131@1|root,COG1131@2|Bacteria,46SHV@74201|Verrucomicrobia,2ITWN@203494|Verrucomicrobiae	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_4728943_2	382464.ABSI01000009_gene3916	2.917e-35	146.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
DTH1_k127_4739843_0	497964.CfE428DRAFT_4166	1.84e-153	499.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DTH1_k127_4739843_1	497964.CfE428DRAFT_5925	5.167e-57	208.0	COG0125@1|root,COG0125@2|Bacteria,46ST1@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DTH1_k127_4739843_2	909663.KI867150_gene972	6.979e-31	124.0	2CIE9@1|root,32S7U@2|Bacteria,1P112@1224|Proteobacteria,431TX@68525|delta/epsilon subdivisions,2WWP3@28221|Deltaproteobacteria,2MS3R@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
DTH1_k127_4769332_0	880526.KE386488_gene1576	2.515e-171	553.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4772913_6	1403819.BATR01000005_gene177	4.892e-09	69.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia,2IVFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,VCBS
DTH1_k127_4772913_0	223192.XP_007915956.1	2.126e-137	458.0	COG4030@1|root,2SKR2@2759|Eukaryota,39W5K@33154|Opisthokonta,3NXCY@4751|Fungi,3QPYP@4890|Ascomycota,21CB8@147550|Sordariomycetes	4751|Fungi	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH1_k127_4772913_5	111781.Lepto7376_3756	6.151e-12	79.0	COG1572@1|root,COG3209@1|root,COG3210@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CARDB,RHS_repeat
DTH1_k127_4772913_2	1403819.BATR01000008_gene271	5.451e-25	111.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH1_k127_4772913_1	1496688.ER33_13835	5.821e-129	414.0	COG0426@1|root,COG0426@2|Bacteria,1GPET@1117|Cyanobacteria,22SW2@167375|Cyanobium	1117|Cyanobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4772913_7	1123035.ARLA01000028_gene2103	2.474e-05	54.0	COG2350@1|root,COG2350@2|Bacteria,4NRC1@976|Bacteroidetes,1I447@117743|Flavobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
DTH1_k127_4772913_3	497964.CfE428DRAFT_0072	4.161e-16	81.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH1_k127_4772913_4	1123277.KB893244_gene5105	5.852e-15	81.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH1_k127_4781317_1	497964.CfE428DRAFT_4938	6.795e-113	372.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
DTH1_k127_4781317_0	497964.CfE428DRAFT_4937	1.113e-115	382.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM phosphate acetyl butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
DTH1_k127_4781317_2	1123242.JH636434_gene3755	2.082e-98	331.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_4784487_0	886293.Sinac_5843	6.621e-45	187.0	COG3210@1|root,COG3391@1|root,COG3420@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,Big_2,Big_5,DUF3494,Haemagg_act
DTH1_k127_4784487_1	243231.GSU0754	2.519e-17	97.0	COG2373@1|root,COG2931@1|root,COG3210@1|root,COG3637@1|root,COG4625@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria,COG4625@2|Bacteria,1QWN8@1224|Proteobacteria,42TGT@68525|delta/epsilon subdivisions,2WQPA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4800738_9	1173028.ANKO01000058_gene3042	0.0009684	46.0	COG1404@1|root,COG2931@1|root,COG4447@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,1G1I0@1117|Cyanobacteria,1HAPI@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,P_proprotein,Peptidase_M10_C,Peptidase_S8
DTH1_k127_4800738_3	278957.ABEA03000104_gene310	3.228e-81	275.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
DTH1_k127_4800738_4	452637.Oter_3648	7.62e-50	190.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
DTH1_k127_4800738_1	471854.Dfer_1899	4.072e-155	499.0	COG4409@1|root,COG4409@2|Bacteria,4NKEW@976|Bacteroidetes,47U77@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_4800738_7	247490.KSU1_D0417	2.151e-13	71.0	COG1052@1|root,COG1052@2|Bacteria,2IWTC@203682|Planctomycetes	203682|Planctomycetes	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH1_k127_4800738_2	641524.ADICYQ_2925	4.523e-143	461.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_4800738_5	234267.Acid_3103	6.766e-45	166.0	COG4948@1|root,COG4948@2|Bacteria,3Y46A@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
DTH1_k127_4800738_6	247490.KSU1_C1333	1.277e-13	82.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_4800738_0	886293.Sinac_6825	2.27e-156	503.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH1_k127_4801046_0	278957.ABEA03000010_gene3912	5.89e-172	550.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH1_k127_4801046_1	1298863.AUEP01000009_gene40	3.523e-14	88.0	COG0681@1|root,COG0681@2|Bacteria,2HES2@201174|Actinobacteria,4DUMF@85009|Propionibacteriales	201174|Actinobacteria	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Peptidase_S24
DTH1_k127_4801046_2	682795.AciX8_3725	2.344e-10	75.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
DTH1_k127_4852048_3	330214.NIDE4374	1.543e-34	136.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DTH1_k127_4852048_0	278957.ABEA03000112_gene1387	1.039e-152	488.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,3K7B2@414999|Opitutae	414999|Opitutae	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
DTH1_k127_4852048_1	452637.Oter_2651	7.425e-104	348.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_4852048_4	330214.NIDE4047	2.482e-27	114.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH1_k127_4852048_2	243231.GSU2683	2.18e-74	261.0	COG1893@1|root,COG1893@2|Bacteria,1RFSW@1224|Proteobacteria,43AIX@68525|delta/epsilon subdivisions,2X5Z6@28221|Deltaproteobacteria,43T9T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2643	ApbA,ApbA_C
DTH1_k127_4854631_0	497964.CfE428DRAFT_4013	2.287e-162	522.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
DTH1_k127_4854631_1	1303518.CCALI_00634	1.606e-26	113.0	28K2K@1|root,2Z9RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4854839_0	452637.Oter_0239	3.394e-195	615.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DTH1_k127_4854839_7	59374.Fisuc_1277	7.689e-06	53.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
DTH1_k127_4854839_3	278957.ABEA03000094_gene4759	2.669e-59	212.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,3K7UE@414999|Opitutae	414999|Opitutae	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
DTH1_k127_4854839_2	1156937.MFUM_210036	6.472e-62	215.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,37GN5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DTH1_k127_4854839_1	497964.CfE428DRAFT_5605	9.259e-87	294.0	COG0081@1|root,COG0081@2|Bacteria,46S7K@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DTH1_k127_4854839_4	1403819.BATR01000191_gene6561	3.397e-45	169.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DTH1_k127_4854839_5	497964.CfE428DRAFT_5603	5.499e-16	79.0	COG0222@1|root,COG0222@2|Bacteria,46SWC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DTH1_k127_486999_0	1396141.BATP01000016_gene2780	2.636e-115	405.0	COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.5.4.40	ko:K18286,ko:K20276	ko00130,ko01110,ko02024,map00130,map01110,map02024	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_8,Big_5,SLH,SWM_repeat
DTH1_k127_486999_2	243231.GSU0006	2.182e-82	290.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
DTH1_k127_486999_4	1123070.KB899247_gene1454	1.426e-43	167.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Glycerol-3-phosphate acyltransferase	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
DTH1_k127_486999_1	497964.CfE428DRAFT_0881	1.925e-107	359.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_486999_3	1156937.MFUM_680012	5.75e-64	238.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,37GGI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
DTH1_k127_4885326_1	694440.JOMF01000004_gene1346	2.233e-23	104.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota,2N9E7@224756|Methanomicrobia	224756|Methanomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_4885326_2	469618.FVAG_00642	3.837e-23	103.0	COG3952@1|root,COG3952@2|Bacteria,37AN1@32066|Fusobacteria	32066|Fusobacteria	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
DTH1_k127_4885326_0	1286106.MPL1_00887	1.489e-57	219.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH1_k127_4885915_1	583355.Caka_0200	1.005e-69	249.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
DTH1_k127_4885915_0	1123278.KB893563_gene4551	8.651e-260	811.0	COG3507@1|root,COG3507@2|Bacteria,4NEVJ@976|Bacteroidetes,47JBZ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM_6,Glyco_hydro_43
DTH1_k127_4885915_2	661478.OP10G_2561	2.41e-23	115.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
DTH1_k127_4886767_1	722419.PH505_co00060	3.864e-33	134.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,2Q2CW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
DTH1_k127_4886767_0	886293.Sinac_0540	2.819e-76	261.0	COG0279@1|root,COG0279@2|Bacteria,2IZQU@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
DTH1_k127_4886767_3	1403819.BATR01000104_gene3607	3.452e-06	52.0	2EKXK@1|root,33EM4@2|Bacteria,46WCN@74201|Verrucomicrobia,2IUG6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_4921959_0	671143.DAMO_0532	0.0	1345.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DTH1_k127_4921959_1	1121354.AQUV01000002_gene956	2.371e-18	86.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,22N5E@1653|Corynebacteriaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DTH1_k127_493785_2	497964.CfE428DRAFT_5266	1.443e-41	158.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_493785_0	1121904.ARBP01000009_gene4249	2.085e-180	576.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH1_k127_493785_1	1121875.KB907550_gene801	1.954e-96	332.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1HYXI@117743|Flavobacteriia	976|Bacteroidetes	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DTH1_k127_493785_3	641524.ADICYQ_2828	6.963e-08	55.0	COG4948@1|root,COG4948@2|Bacteria,4NE9A@976|Bacteroidetes,47NDY@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
DTH1_k127_496433_0	497964.CfE428DRAFT_5270	4.888e-71	246.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH1_k127_496433_1	404589.Anae109_3548	4.256e-68	265.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
DTH1_k127_4987397_0	208439.AJAP_24615	5.18e-136	473.0	COG1361@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4935@2|Bacteria,2I2W6@201174|Actinobacteria,4EDRS@85010|Pseudonocardiales	201174|Actinobacteria	MO	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
DTH1_k127_5008719_1	240016.ABIZ01000001_gene2350	1.437e-31	126.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH1_k127_5008719_3	886293.Sinac_7506	2.64e-08	65.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH1_k127_5008719_2	216594.MMAR_5269	4.846e-09	70.0	COG4402@1|root,COG4402@2|Bacteria,2I90K@201174|Actinobacteria,236XA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
DTH1_k127_5008719_0	497964.CfE428DRAFT_0815	9.767e-246	766.0	COG1482@1|root,COG1482@2|Bacteria,46VQS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5026686_1	504472.Slin_2839	2.976e-115	385.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_5026686_0	240016.ABIZ01000001_gene281	2.314e-172	546.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
DTH1_k127_504898_0	1140.Synpcc7942_0722	4.492e-45	179.0	28JXH@1|root,2ZA3Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RecT
DTH1_k127_5066303_1	251221.35213668	1.732e-26	111.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH1_k127_5066303_2	661478.OP10G_3764	6.638e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_5066303_0	497964.CfE428DRAFT_2042	3.08e-66	228.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH1_k127_5066392_2	344747.PM8797T_04855	7.791e-10	61.0	COG2165@1|root,COG2165@2|Bacteria,2J1YI@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_5066392_3	1396141.BATP01000006_gene5432	6.289e-06	58.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH1_k127_5066392_1	452637.Oter_3823	5.951e-67	244.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5066392_0	452637.Oter_3823	5.601e-177	571.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5067445_1	1396141.BATP01000002_gene4802	4.325e-177	559.0	COG0387@1|root,COG0387@2|Bacteria,46UPT@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
DTH1_k127_5067445_2	768671.ThimaDRAFT_0622	4.582e-49	186.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,1WZGU@135613|Chromatiales	135613|Chromatiales	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH1_k127_5067445_0	1396141.BATP01000001_gene5389	9.67e-231	726.0	COG0659@1|root,COG0659@2|Bacteria,46TUB@74201|Verrucomicrobia,2IVJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
DTH1_k127_5067445_3	224911.27351746	7.957e-13	69.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2TTM8@28211|Alphaproteobacteria,3JW7P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
DTH1_k127_5072313_2	945713.IALB_0509	1.095e-59	216.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
DTH1_k127_5072313_1	945713.IALB_0510	2.117e-104	350.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
DTH1_k127_5072313_0	385682.AFSL01000102_gene55	1.379e-205	649.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
DTH1_k127_5072313_3	1403819.BATR01000062_gene1902	2.005e-31	128.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,2IW1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH1_k127_5084622_2	43354.JOIJ01000012_gene959	1.914e-14	76.0	COG3568@1|root,COG3568@2|Bacteria,2HEP6@201174|Actinobacteria,4E819@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH1_k127_5084622_0	497964.CfE428DRAFT_4279	1.574e-161	521.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase middle domain protein	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH1_k127_5084622_1	903818.KI912268_gene1381	4.347e-42	164.0	COG3863@1|root,COG3863@2|Bacteria	2|Bacteria	T	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
DTH1_k127_5090415_0	2340.JV46_09630	1.717e-192	612.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
DTH1_k127_5090415_1	448385.sce4706	8.494e-143	466.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH1_k127_5090415_2	583355.Caka_0067	1.684e-118	389.0	COG0437@1|root,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
DTH1_k127_5090415_5	706587.Desti_4133	3.28e-26	118.0	28JYU@1|root,2Z9NZ@2|Bacteria,1N5J2@1224|Proteobacteria,42UJJ@68525|delta/epsilon subdivisions,2X7XY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5090415_3	497964.CfE428DRAFT_2435	8.264e-47	177.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
DTH1_k127_5090415_7	1385521.N803_05605	6.086e-06	52.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4FG9T@85021|Intrasporangiaceae	201174|Actinobacteria	M	sugar transferase	epsL	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
DTH1_k127_5090415_4	1192034.CAP_8221	5.563e-39	158.0	2C9T2@1|root,347D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5094162_3	485913.Krac_6839	3.183e-08	56.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
DTH1_k127_5094162_0	1297742.A176_06707	7.961e-73	261.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
DTH1_k127_5094162_5	1144342.PMI40_00304	0.0002146	51.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQV@28216|Betaproteobacteria,474MH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
DTH1_k127_5094162_2	1385517.N800_00590	2.694e-08	64.0	COG4795@1|root,COG4795@2|Bacteria,1MYPS@1224|Proteobacteria,1SHGQ@1236|Gammaproteobacteria,1X6ZS@135614|Xanthomonadales	135614|Xanthomonadales	U	General secretion pathway protein	xpsJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_5094162_1	933262.AXAM01000042_gene1817	4.387e-27	124.0	COG1555@1|root,COG3156@1|root,COG1555@2|Bacteria,COG3156@2|Bacteria,1PQMW@1224|Proteobacteria,42T9B@68525|delta/epsilon subdivisions,2WPYT@28221|Deltaproteobacteria,2MKAN@213118|Desulfobacterales	28221|Deltaproteobacteria	LU	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
DTH1_k127_5100896_1	497964.CfE428DRAFT_1025	2.388e-71	248.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	2.1.1.331,2.1.1.332	ko:K13601,ko:K13602	ko00860,ko01110,map00860,map01110	-	R11507,R11508,R11509	RC03457,RC03458,RC03459	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH1_k127_5100896_2	497964.CfE428DRAFT_1024	9.486e-40	152.0	2EBIG@1|root,335IZ@2|Bacteria,46WF8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5100896_0	240016.ABIZ01000001_gene654	4.552e-80	277.0	COG0583@1|root,COG0583@2|Bacteria,46V15@74201|Verrucomicrobia,2IUGE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
DTH1_k127_5100896_3	404589.Anae109_0686	4.005e-28	126.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DTH1_k127_5100896_4	1195246.AGRI_14210	1.01e-15	90.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,465HK@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG4796 Type II secretory pathway, component HofQ	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
DTH1_k127_5103107_6	452637.Oter_4609	6.719e-92	310.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DTH1_k127_5103107_4	1396418.BATQ01000078_gene597	3.093e-129	424.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia,2IVAY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH1_k127_5103107_5	452637.Oter_1514	1.185e-114	376.0	COG1136@1|root,COG1136@2|Bacteria,46YZ8@74201|Verrucomicrobia,3K9FX@414999|Opitutae	414999|Opitutae	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_5103107_2	1403819.BATR01000150_gene5077	7.079e-155	499.0	COG0577@1|root,COG0577@2|Bacteria,46UT6@74201|Verrucomicrobia,2IVGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_5103107_0	1396418.BATQ01000078_gene594	8.082e-169	538.0	COG0577@1|root,COG0577@2|Bacteria,46UQN@74201|Verrucomicrobia,2IVBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_5103107_8	452637.Oter_0096	4.564e-63	239.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5103107_7	452637.Oter_0095	1.989e-68	254.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia,3K7T2@414999|Opitutae	414999|Opitutae	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5103107_3	240016.ABIZ01000001_gene2203	2.73e-136	443.0	COG2021@1|root,COG2021@2|Bacteria,46U58@74201|Verrucomicrobia,2ITGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
DTH1_k127_5103107_1	1403819.BATR01000087_gene2529	4.733e-163	516.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH1_k127_5110880_1	1123242.JH636435_gene2066	5.533e-44	175.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DTH1_k127_5110880_0	1274374.CBLK010000061_gene596	2.781e-115	383.0	2CAEK@1|root,2ZCPG@2|Bacteria,1U07Z@1239|Firmicutes,4I9IQ@91061|Bacilli,271MJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5111536_1	1121920.AUAU01000024_gene2384	2.387e-29	126.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
DTH1_k127_5111536_0	1121920.AUAU01000024_gene2382	1.998e-198	652.0	COG3303@1|root,COG4733@1|root,COG3303@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Big_2,DUF285,HYR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N,Paired_CXXCH_1,SLH,fn3
DTH1_k127_5111536_2	579138.Zymop_1135	2.855e-26	115.0	COG1959@1|root,COG1959@2|Bacteria,1RGUG@1224|Proteobacteria,2UANJ@28211|Alphaproteobacteria,2K4GF@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH1_k127_5126381_0	1345023.M467_12970	6.95e-171	546.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,3WDYC@539002|Bacillales incertae sedis	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DTH1_k127_5134887_8	1415166.NONO_c61490	3.196e-06	50.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4G061@85025|Nocardiaceae	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_5134887_0	1121033.AUCF01000009_gene1174	8.43e-133	428.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,2JSGM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG3959 Transketolase, N-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DTH1_k127_5134887_2	1121033.AUCF01000009_gene1173	1.077e-121	397.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,2JSWY@204441|Rhodospirillales	204441|Rhodospirillales	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH1_k127_5134887_6	1121440.AUMA01000005_gene2574	4.832e-81	291.0	COG0546@1|root,COG3173@1|root,COG0546@2|Bacteria,COG3173@2|Bacteria,1R5MY@1224|Proteobacteria,435UQ@68525|delta/epsilon subdivisions,2X9D0@28221|Deltaproteobacteria,2MBGQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
DTH1_k127_5134887_7	756272.Plabr_2390	1.867e-51	194.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
DTH1_k127_5134887_5	497964.CfE428DRAFT_3169	2.359e-91	317.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
DTH1_k127_5134887_1	497964.CfE428DRAFT_0922	3.033e-129	422.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH1_k127_5134887_9	96561.Dole_1196	8.771e-05	53.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
DTH1_k127_5134887_3	1156937.MFUM_1020111	2.205e-118	396.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,37FVJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
DTH1_k127_5134887_4	1121428.DESHY_110314___1	1.082e-107	374.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,260SC@186807|Peptococcaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
DTH1_k127_5143524_0	1123242.JH636435_gene1197	1.072e-140	452.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH1_k127_5143524_1	661478.OP10G_0861	6.753e-131	429.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH1_k127_5143524_3	344747.PM8797T_29862	1.687e-86	297.0	COG1082@1|root,COG1082@2|Bacteria,2J0ZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_5143524_2	247634.GPB2148_1563	5.451e-88	304.0	COG3746@1|root,COG3746@2|Bacteria,1NT6B@1224|Proteobacteria,1SM5C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH1_k127_5143524_4	290397.Adeh_4006	1.1e-82	284.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH1_k127_5144696_6	497964.CfE428DRAFT_1398	1.062e-104	349.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U11@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_5144696_10	945713.IALB_0431	1.146e-52	194.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DTH1_k127_5144696_16	909663.KI867150_gene1096	3.095e-19	93.0	294CD@1|root,2ZRSF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5144696_5	909663.KI867150_gene1095	1.435e-106	356.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
DTH1_k127_5144696_3	909663.KI867150_gene1094	6.753e-230	729.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42SY2@68525|delta/epsilon subdivisions,2X5C4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
DTH1_k127_5144696_12	452637.Oter_1848	2.162e-37	144.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH1_k127_5144696_15	909663.KI867150_gene1093	7.187e-31	125.0	COG0636@1|root,COG0636@2|Bacteria,1NG0V@1224|Proteobacteria,42XT7@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
DTH1_k127_5144696_13	909663.KI867150_gene1092	1.125e-36	140.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
DTH1_k127_5144696_9	909663.KI867150_gene1091	1.699e-59	214.0	2FA6P@1|root,342FE@2|Bacteria	2|Bacteria	S	ATP synthase (E/31 kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
DTH1_k127_5144696_0	909663.KI867150_gene1090	0.0	1016.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
DTH1_k127_5144696_1	909663.KI867150_gene1089	8.847e-273	845.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH1_k127_5144696_7	909663.KI867150_gene1088	1.387e-90	303.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
DTH1_k127_5144696_14	296591.Bpro_3359	4.459e-33	133.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
DTH1_k127_5144696_11	1123368.AUIS01000029_gene1290	3.952e-49	182.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
DTH1_k127_5144696_17	1121939.L861_16535	2.945e-10	62.0	COG2331@1|root,COG2331@2|Bacteria,1NMRY@1224|Proteobacteria	1224|Proteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH1_k127_5144696_18	880073.Calab_3105	6.101e-07	62.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
DTH1_k127_5144696_8	234267.Acid_1882	1.825e-76	264.0	2DF1J@1|root,2ZQ4G@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH1_k127_5144696_4	234267.Acid_1881	9.695e-115	377.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_5144696_2	880073.Calab_3105	6.243e-230	727.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
DTH1_k127_5149193_3	1162668.LFE_1500	2.72e-33	135.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
DTH1_k127_5149193_1	452637.Oter_2584	4.518e-134	443.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
DTH1_k127_5149193_0	1379698.RBG1_1C00001G0297	1.48e-135	449.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
DTH1_k127_5149193_2	1379698.RBG1_1C00001G0296	1.8e-56	199.0	COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	ttrB	-	-	ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4_11,Fer4_3,Fer4_7
DTH1_k127_5159316_2	324057.Pjdr2_4676	8.814e-15	85.0	COG1409@1|root,COG3291@1|root,COG3537@1|root,COG3693@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG3537@2|Bacteria,COG3693@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,26VY4@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_92
DTH1_k127_5159316_1	1396418.BATQ01000025_gene5257	9.757e-42	162.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,2IUGA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
DTH1_k127_5159316_0	1535287.JP74_20325	2.979e-114	381.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
DTH1_k127_5159316_3	886293.Sinac_6923	1.339e-08	56.0	COG2159@1|root,COG2159@2|Bacteria,2IZCY@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DTH1_k127_5159675_1	926560.KE387027_gene1014	6.011e-08	68.0	COG2247@1|root,COG2247@2|Bacteria,1WNI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5159675_0	52598.EE36_14662	7.949e-37	163.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3ZUZ8@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
DTH1_k127_5164374_3	395493.BegalDRAFT_2362	1.101e-63	227.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,461AE@72273|Thiotrichales	72273|Thiotrichales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
DTH1_k127_5164374_5	1254432.SCE1572_38305	2.165e-17	91.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	pp2c12	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
DTH1_k127_5164374_2	452637.Oter_3080	4.137e-69	246.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
DTH1_k127_5164374_4	1121033.AUCF01000020_gene699	4.89e-39	154.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yqfZ	-	-	-	-	-	-	-	-	-	-	-	LysM
DTH1_k127_5164374_1	118168.MC7420_3120	2.337e-127	431.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H72F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
DTH1_k127_5164374_0	330214.NIDE0551	2.307e-166	550.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
DTH1_k127_5169650_1	497964.CfE428DRAFT_4304	4.245e-88	300.0	COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DTH1_k127_5169650_3	1121447.JONL01000003_gene3115	1.874e-39	158.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MBDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	hydrolase, HAD-superfamily, subfamily IIIA	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
DTH1_k127_5169650_5	886293.Sinac_6222	8.787e-14	81.0	COG2165@1|root,COG2165@2|Bacteria,2J4VP@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_5169650_4	378806.STAUR_1759	1.777e-19	104.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
DTH1_k127_5169650_0	378806.STAUR_7504	8.785e-161	544.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QUYA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
DTH1_k127_5169650_2	497964.CfE428DRAFT_5731	7.579e-64	225.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_5169650_6	497964.CfE428DRAFT_6370	1.74e-11	64.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
DTH1_k127_5171206_3	1396418.BATQ01000168_gene1810	2.094e-11	76.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DTH1_k127_5171206_0	1123242.JH636435_gene2138	1.335e-140	458.0	COG0673@1|root,COG0673@2|Bacteria,2IX05@203682|Planctomycetes	203682|Planctomycetes	S	NADH-dependent dyhydrogenase related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_5171206_1	1173028.ANKO01000246_gene4011	1.998e-69	240.0	COG2110@1|root,COG2110@2|Bacteria,1G5VN@1117|Cyanobacteria,1HB5V@1150|Oscillatoriales	1117|Cyanobacteria	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
DTH1_k127_5171206_4	479435.Kfla_5346	0.0008199	48.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DTH1_k127_5171206_2	1335757.SPICUR_06740	8.47e-33	128.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RQ0G@1236|Gammaproteobacteria,1WXEX@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH1_k127_518781_7	1121403.AUCV01000010_gene1377	3.891e-51	201.0	COG2885@1|root,COG3221@1|root,COG2885@2|Bacteria,COG3221@2|Bacteria,1R687@1224|Proteobacteria,42ZCB@68525|delta/epsilon subdivisions,2WTSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,OmpA
DTH1_k127_518781_8	1238190.AMQY01000023_gene441	3.428e-15	87.0	COG2304@1|root,COG2304@2|Bacteria,1RGCN@1224|Proteobacteria,1S5GI@1236|Gammaproteobacteria,1XPSH@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
DTH1_k127_518781_5	335543.Sfum_3489	5.725e-103	358.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,1QU25@1224|Proteobacteria,42YRH@68525|delta/epsilon subdivisions,2WUGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
DTH1_k127_518781_10	1123400.KB904788_gene192	1.41e-05	58.0	COG3266@1|root,COG3266@2|Bacteria,1R0CZ@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH1_k127_518781_11	3694.POPTR_0006s25110.1	5.46e-05	55.0	2CN88@1|root,2QUFZ@2759|Eukaryota,37NST@33090|Viridiplantae,3GD0N@35493|Streptophyta,4JGBC@91835|fabids	35493|Streptophyta	S	glycine-rich protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_518781_0	234267.Acid_2664	1.103e-202	642.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
DTH1_k127_518781_2	330214.NIDE1620	6.369e-136	441.0	COG1118@1|root,COG1118@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25,3.6.3.29	ko:K02017,ko:K02045,ko:K10112,ko:K16787	ko00920,ko02010,map00920,map02010	M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00582,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE,TOBE_3
DTH1_k127_518781_3	1121035.AUCH01000001_gene1959	1.902e-123	404.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,2KV49@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysW	-	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
DTH1_k127_518781_4	640081.Dsui_0260	6.626e-112	370.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KV4D@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
DTH1_k127_518781_1	1122236.KB905142_gene569	2.493e-149	481.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KKVC@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
DTH1_k127_518781_9	1288494.EBAPG3_24600	4.705e-08	55.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,2W0HU@28216|Betaproteobacteria,373ZH@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
DTH1_k127_5203632_2	234267.Acid_5864	1.018e-57	214.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_5203632_4	761193.Runsl_2772	3.656e-50	190.0	COG0329@1|root,COG0329@2|Bacteria,4NI1I@976|Bacteroidetes,47NMJ@768503|Cytophagia	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH1_k127_5203632_0	1123242.JH636436_gene23	1.092e-154	505.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_5203632_5	522306.CAP2UW1_1267	1.6e-18	93.0	2EBP0@1|root,335P6@2|Bacteria,1N33Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5203632_1	575540.Isop_2535	5.304e-76	265.0	COG0580@1|root,COG0580@2|Bacteria,2IZDN@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DTH1_k127_5203632_3	525897.Dbac_1089	6.626e-55	199.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria,2MFM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5203632_6	1454004.AW11_02387	1.142e-10	66.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
DTH1_k127_5230996_2	696747.NIES39_A01900	2.571e-34	138.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
DTH1_k127_5230996_1	1396418.BATQ01000056_gene181	3.252e-99	334.0	COG4188@1|root,COG4188@2|Bacteria,46TTD@74201|Verrucomicrobia,2IVPV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
DTH1_k127_5230996_0	1123242.JH636435_gene1598	1.902e-106	354.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DTH1_k127_5242397_1	497964.CfE428DRAFT_4587	3.047e-232	725.0	COG2895@1|root,COG2895@2|Bacteria,46SN4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
DTH1_k127_5242397_2	452637.Oter_2430	6.826e-169	533.0	COG0175@1|root,COG0175@2|Bacteria,46TUQ@74201|Verrucomicrobia,3K7NR@414999|Opitutae	74201|Verrucomicrobia	H	PFAM phosphoadenosine phosphosulfate reductase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH1_k127_5242397_5	497964.CfE428DRAFT_4585	1.996e-112	365.0	COG0175@1|root,COG0175@2|Bacteria,46SNE@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH1_k127_5242397_0	452637.Oter_2432	7.918e-259	807.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,3K77C@414999|Opitutae	414999|Opitutae	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
DTH1_k127_5242397_4	497964.CfE428DRAFT_4701	7.558e-116	387.0	COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DTH1_k127_5242397_3	1156937.MFUM_870060	6.498e-130	421.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,37GGN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
DTH1_k127_5242397_6	497964.CfE428DRAFT_1544	2.227e-55	204.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DTH1_k127_5242397_7	111781.Lepto7376_3170	9.656e-50	184.0	COG0193@1|root,COG0193@2|Bacteria,1G0D0@1117|Cyanobacteria,1H70D@1150|Oscillatoriales	1117|Cyanobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DTH1_k127_5242397_9	478741.JAFS01000001_gene1845	8.799e-12	69.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,37GXZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DTH1_k127_5242397_8	794903.OPIT5_19655	7.163e-42	163.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH1_k127_5271648_0	497964.CfE428DRAFT_0257	7.411e-211	685.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
DTH1_k127_5273014_0	1038860.AXAP01000015_gene2094	1.242e-270	838.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,3JRH2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	aldehyde-lyase activity	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
DTH1_k127_5273014_1	1449049.JONW01000013_gene4657	1.29e-115	388.0	COG5164@1|root,COG5164@2|Bacteria,1MX1Z@1224|Proteobacteria,2TWHE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5301227_6	1286632.P278_17170	1.988e-13	78.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DTH1_k127_5301227_0	497964.CfE428DRAFT_3889	1.266e-128	428.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH1_k127_5301227_1	497964.CfE428DRAFT_3890	1.072e-83	290.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DTH1_k127_5301227_4	316067.Geob_2610	6.255e-14	74.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DTH1_k127_5301227_5	313628.LNTAR_24436	1.353e-13	78.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
DTH1_k127_5301227_2	497964.CfE428DRAFT_3893	4.53e-56	201.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH1_k127_5301227_3	404380.Gbem_0296	8.642e-47	192.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
DTH1_k127_5301227_7	1144319.PMI16_03860	0.0004237	48.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,478QH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
DTH1_k127_5302611_7	1117319.PSPO_04287	3.016e-15	79.0	COG1520@1|root,COG1520@2|Bacteria,1N8KC@1224|Proteobacteria,1SF02@1236|Gammaproteobacteria,2Q4VQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_5302611_8	1487923.DP73_02105	2.1e-13	76.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,2609M@186807|Peptococcaceae	186801|Clostridia	F	TIGRFAM Pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
DTH1_k127_5302611_2	1121428.DESHY_40194___1	3.139e-107	354.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,263IX@186807|Peptococcaceae	186801|Clostridia	G	Major intrinsic protein	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	iHN637.CLJU_RS07630	MIP
DTH1_k127_5302611_0	243231.GSU2762	1.734e-227	715.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
DTH1_k127_5302611_3	756272.Plabr_3925	1.895e-85	291.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH1_k127_5302611_4	1396418.BATQ01000013_gene4380	1.295e-82	284.0	COG0515@1|root,COG0515@2|Bacteria,46UMT@74201|Verrucomicrobia,2IVH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,PG_binding_1,Pkinase
DTH1_k127_5302611_1	497964.CfE428DRAFT_0790	1.309e-187	597.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
DTH1_k127_5302611_6	639030.JHVA01000001_gene2022	3.052e-36	150.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
DTH1_k127_5302611_5	946483.Cenrod_1961	1.024e-39	153.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VMDU@28216|Betaproteobacteria,4AJA8@80864|Comamonadaceae	28216|Betaproteobacteria	L	Group II intron, maturase-specific domain	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
DTH1_k127_5302611_9	933262.AXAM01000191_gene3347	9.016e-05	44.0	COG3668@1|root,COG3668@2|Bacteria,1N8DJ@1224|Proteobacteria,42VZU@68525|delta/epsilon subdivisions,2WRB9@28221|Deltaproteobacteria,2MM4U@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5304973_1	497964.CfE428DRAFT_2656	1.016e-80	283.0	2EQIM@1|root,2ZBQ8@2|Bacteria,46TFZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
DTH1_k127_5304973_5	497964.CfE428DRAFT_2655	1.207e-26	112.0	2ES4R@1|root,33JPJ@2|Bacteria,46T9B@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5304973_9	398767.Glov_3581	2.332e-14	83.0	2B0DH@1|root,31SQS@2|Bacteria,1P6ED@1224|Proteobacteria,4328H@68525|delta/epsilon subdivisions,2WXMR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5304973_4	439235.Dalk_0968	4.539e-31	129.0	2ECUE@1|root,336RY@2|Bacteria,1P3V9@1224|Proteobacteria,431ZA@68525|delta/epsilon subdivisions,2WX45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5304973_8	583355.Caka_1232	2.312e-22	109.0	COG5523@1|root,COG5523@2|Bacteria,46ZK6@74201|Verrucomicrobia,3KA3R@414999|Opitutae	2|Bacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
DTH1_k127_5304973_11	771875.Ferpe_1246	9.727e-10	62.0	COG0230@1|root,COG0230@2|Bacteria,2GDMP@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DTH1_k127_5304973_10	756499.Desde_4254	1.815e-11	70.0	COG0594@1|root,COG0594@2|Bacteria,1TV50@1239|Firmicutes,259HJ@186801|Clostridia,2633N@186807|Peptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DTH1_k127_5304973_7	1244869.H261_16660	3.446e-23	104.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2JTTP@204441|Rhodospirillales	204441|Rhodospirillales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DTH1_k127_5304973_0	583355.Caka_2475	6.138e-88	313.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,3K72P@414999|Opitutae	414999|Opitutae	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
DTH1_k127_5304973_6	497964.CfE428DRAFT_1418	7.571e-25	109.0	COG1847@1|root,COG1847@2|Bacteria,46VYD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	R3H
DTH1_k127_5304973_3	497964.CfE428DRAFT_4578	1.549e-37	146.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
DTH1_k127_5304973_2	497964.CfE428DRAFT_4579	3.669e-49	181.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH1_k127_5313791_0	452637.Oter_1547	2.451e-158	503.0	COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,3K82Q@414999|Opitutae	414999|Opitutae	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DTH1_k127_5313791_3	1210884.HG799465_gene12051	1.208e-08	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_5313791_2	278957.ABEA03000062_gene3554	4.681e-13	79.0	COG2165@1|root,COG2165@2|Bacteria,46YIN@74201|Verrucomicrobia,3K9NX@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH1_k127_5313791_1	240016.ABIZ01000001_gene1545	2.366e-45	170.0	COG0346@1|root,COG0346@2|Bacteria,46SUF@74201|Verrucomicrobia,2IUKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH1_k127_5313791_4	1089553.Tph_c26760	2.392e-06	52.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,42FAT@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
DTH1_k127_5348571_5	686340.Metal_3863	1.077e-05	47.0	COG2084@1|root,COG2084@2|Bacteria,1NS71@1224|Proteobacteria,1S043@1236|Gammaproteobacteria,1XEIU@135618|Methylococcales	135618|Methylococcales	C	6-phosphogluconate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
DTH1_k127_5348571_3	497964.CfE428DRAFT_2594	1.55e-60	219.0	COG2138@1|root,COG2138@2|Bacteria,46SPE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
DTH1_k127_5348571_4	324602.Caur_0211	7.314e-15	91.0	COG1319@1|root,COG3391@1|root,COG1319@2|Bacteria,COG3391@2|Bacteria,2GA7F@200795|Chloroflexi,376QS@32061|Chloroflexia	32061|Chloroflexia	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5348571_0	1396141.BATP01000006_gene5432	1.354e-126	460.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH1_k127_5348571_2	1396141.BATP01000034_gene4198	5.37e-64	254.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
DTH1_k127_5348571_6	1274374.CBLK010000059_gene442	0.0006721	55.0	COG1520@1|root,COG1621@1|root,COG4724@1|root,COG1520@2|Bacteria,COG1621@2|Bacteria,COG4724@2|Bacteria,1TPGB@1239|Firmicutes,4HEA6@91061|Bacilli,275I9@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 85	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_6,Glyco_hydro_85
DTH1_k127_5348571_1	497964.CfE428DRAFT_1451	3.083e-92	312.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DTH1_k127_5357273_1	1279017.AQYJ01000023_gene3265	8.727e-71	265.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	2.4.1.10	ko:K00692	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R05140	RC00077	ko00000,ko00001,ko01000,ko01003	-	GH68	-	Alpha-L-AF_C,Alpha-amylase,Big_2,CBM_4_9,Glyco_hydro_32N,Glyco_hydro_43,Glyco_hydro_66,Glyco_hydro_68,Laminin_G_3,PUD,SLH,VCBS
DTH1_k127_5357273_0	1168289.AJKI01000021_gene1764	3.053e-106	357.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,2FPX5@200643|Bacteroidia,3XJSQ@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2
DTH1_k127_5374369_0	1173027.Mic7113_2682	2.509e-166	541.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
DTH1_k127_5394094_0	1156937.MFUM_230006	4.526e-103	352.0	COG1956@1|root,COG2203@1|root,COG4191@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,37G69@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
DTH1_k127_5394094_1	574087.Acear_2177	7.724e-28	127.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,24CCP@186801|Clostridia,3WAFW@53433|Halanaerobiales	186801|Clostridia	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH1_k127_5394094_2	497964.CfE428DRAFT_0332	2.657e-26	115.0	COG2518@1|root,COG2518@2|Bacteria,46UEK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
DTH1_k127_5418374_1	111780.Sta7437_4041	1.551e-108	354.0	COG1902@1|root,COG1902@2|Bacteria,1FZYT@1117|Cyanobacteria,3VIN3@52604|Pleurocapsales	1117|Cyanobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
DTH1_k127_5418374_2	1173026.Glo7428_3316	5.776e-61	218.0	COG0432@1|root,COG0432@2|Bacteria,1G61Z@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH1_k127_5418374_0	1123242.JH636434_gene3629	2.874e-118	391.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
DTH1_k127_5418374_3	290512.Paes_2385	1.099e-58	216.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH1_k127_5420364_3	1123508.JH636439_gene1281	0.0002207	45.0	COG2304@1|root,COG2304@2|Bacteria,2IXP0@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
DTH1_k127_5420364_0	1121403.AUCV01000002_gene446	9.787e-62	225.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,42P50@68525|delta/epsilon subdivisions,2WKU5@28221|Deltaproteobacteria,2MMX2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
DTH1_k127_5420364_1	533240.CRC_01736	8.627e-07	58.0	COG4276@1|root,COG4276@2|Bacteria,1G939@1117|Cyanobacteria,1HNWV@1161|Nostocales	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5420364_2	1121106.JQKB01000041_gene1565	0.0001484	47.0	COG1176@1|root,COG1176@2|Bacteria,1MVFG@1224|Proteobacteria,2TSSR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component I	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
DTH1_k127_5424578_2	1121440.AUMA01000005_gene2575	1.932e-43	165.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2WQ8F@28221|Deltaproteobacteria,2MB41@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH1_k127_5424578_0	402777.KB235904_gene3439	6.394e-135	446.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1G2IU@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM rfaE bifunctional protein, domain I	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
DTH1_k127_5424578_1	614083.AWQR01000023_gene151	1.969e-54	195.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_5426399_1	1237149.C900_03088	5.835e-43	164.0	2E3CB@1|root,32YBM@2|Bacteria,4PPUF@976|Bacteroidetes	2|Bacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
DTH1_k127_5426399_0	497964.CfE428DRAFT_4749	1.113e-103	367.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K13598,ko:K13924	ko02020,ko02030,map02020,map02030	M00498,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	ABC_sub_bind,CHASE4,GAF,HAMP,HATPase_c,HDOD,HisKA,PAS,PAS_3,PAS_4,PAS_9
DTH1_k127_5436442_2	1396141.BATP01000027_gene1089	5.429e-39	162.0	COG5373@1|root,COG5373@2|Bacteria,46S9T@74201|Verrucomicrobia,2IUWT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
DTH1_k127_5436442_3	497964.CfE428DRAFT_4665	2.8e-34	140.0	COG0781@1|root,COG0781@2|Bacteria,46T7V@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DTH1_k127_5436442_1	1379698.RBG1_1C00001G1246	6.618e-65	235.0	COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria	2|Bacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
DTH1_k127_5436442_0	313628.LNTAR_04061	1.013e-74	259.0	COG0552@1|root,COG0552@2|Bacteria	2|Bacteria	U	SRP-dependent cotranslational protein targeting to membrane	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DTH1_k127_5446532_1	575540.Isop_0616	2.165e-68	248.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
DTH1_k127_5446532_0	530564.Psta_1668	1.347e-128	426.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_5446532_2	1120966.AUBU01000002_gene1998	1.124e-05	55.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5446535_0	243090.RB700	1.003e-311	972.0	COG3408@1|root,COG3408@2|Bacteria,2J2NJ@203682|Planctomycetes	203682|Planctomycetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH1_k127_5446535_1	497964.CfE428DRAFT_1804	5.231e-13	77.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH1_k127_5455105_0	1453501.JELR01000001_gene3053	7.988e-74	259.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,464CX@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
DTH1_k127_5455105_1	324057.Pjdr2_3895	3.991e-10	69.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,26S7A@186822|Paenibacillaceae	91061|Bacilli	M	Stage V sporulation protein d	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH1_k127_5462775_0	521674.Plim_1473	7.247e-71	247.0	COG0515@1|root,COG0515@2|Bacteria,2J50A@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Serine threonine protein kinase-related	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,dCache_1
DTH1_k127_5462775_1	443143.GM18_0341	1.515e-32	143.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5466533_3	497964.CfE428DRAFT_2817	1.19e-46	181.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,46UEP@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
DTH1_k127_5466533_2	748247.AZKH_p0390	3.17e-56	205.0	COG0835@1|root,COG0835@2|Bacteria,1RIUD@1224|Proteobacteria,2VSFU@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis signal transduction protein	wspD	-	-	ko:K13489	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
DTH1_k127_5466533_1	240016.ABIZ01000001_gene190	9.573e-100	340.0	COG1352@1|root,COG1352@2|Bacteria,46U91@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Methyltransferase, chemotaxis proteins	-	-	-	-	-	-	-	-	-	-	-	-	CheR,TPR_2
DTH1_k127_5466533_4	629265.PMA4326_11447	1.795e-37	146.0	COG0835@1|root,COG0835@2|Bacteria,1N0R3@1224|Proteobacteria,1SG9X@1236|Gammaproteobacteria,1Z7ZK@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	NT	COG0835 Chemotaxis signal transduction protein	wspB	-	-	ko:K13488	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
DTH1_k127_5466533_0	1122132.AQYH01000005_gene433	1.783e-124	408.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,4B9N4@82115|Rhizobiaceae	28211|Alphaproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
DTH1_k127_5468681_3	478741.JAFS01000002_gene322	1.851e-113	387.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,37G1G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
DTH1_k127_5468681_6	289376.THEYE_A0281	5.764e-20	95.0	COG1862@1|root,COG1862@2|Bacteria,3J0UB@40117|Nitrospirae	40117|Nitrospirae	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
DTH1_k127_5468681_1	240016.ABIZ01000001_gene3247	8.469e-143	462.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,2IU5S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH1_k127_5468681_5	497964.CfE428DRAFT_5371	9.899e-57	210.0	COG4121@1|root,COG4121@2|Bacteria	2|Bacteria	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151	ko:K00773,ko:K07319,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110	-	R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko02048,ko03016	-	-	-	DAO,Methyltransf_30
DTH1_k127_5468681_8	671143.DAMO_2125	1.263e-14	77.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH1_k127_5468681_7	382464.ABSI01000001_gene4245	1.135e-18	94.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DTH1_k127_5468681_4	497964.CfE428DRAFT_2716	2.03e-96	326.0	COG0533@1|root,COG0533@2|Bacteria,46SEH@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DTH1_k127_5468681_2	497964.CfE428DRAFT_2715	2.907e-124	412.0	COG0793@1|root,COG0793@2|Bacteria,46SM7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH1_k127_5468681_0	497964.CfE428DRAFT_0809	1.152e-180	574.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5487217_2	118161.KB235922_gene1342	8.134e-62	229.0	COG3420@1|root,COG3420@2|Bacteria,1GPUW@1117|Cyanobacteria,3VJI4@52604|Pleurocapsales	1117|Cyanobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_5487217_1	1158294.JOMI01000007_gene112	7.881e-166	534.0	COG5434@1|root,COG5434@2|Bacteria,4NIYD@976|Bacteroidetes,2FRQ9@200643|Bacteroidia	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
DTH1_k127_5487217_0	1396141.BATP01000030_gene3773	0.0	1059.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
DTH1_k127_5487217_3	240016.ABIZ01000001_gene63	1.066e-07	66.0	COG1793@1|root,COG1793@2|Bacteria,46TK9@74201|Verrucomicrobia,2IV60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_549542_5	278957.ABEA03000189_gene956	4.565e-48	178.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
DTH1_k127_549542_0	278957.ABEA03000189_gene958	6.083e-212	667.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH1_k127_549542_4	794903.OPIT5_22590	2.684e-60	214.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
DTH1_k127_549542_6	794903.OPIT5_22595	6.059e-42	163.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia,3K7Z7@414999|Opitutae	414999|Opitutae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH1_k127_549542_3	452637.Oter_3930	6.78e-69	250.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,3K79U@414999|Opitutae	414999|Opitutae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_549542_9	452637.Oter_3929	0.000182	49.0	2B8Q9@1|root,321ZW@2|Bacteria,46XX6@74201|Verrucomicrobia,3K8IF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_549542_2	794903.OPIT5_22615	1.694e-90	316.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
DTH1_k127_549542_7	1123508.JH636443_gene5054	7.764e-36	151.0	COG2993@1|root,COG2993@2|Bacteria,2IZNM@203682|Planctomycetes	203682|Planctomycetes	C	COGs COG2993 Cbb3-type cytochrome oxidase cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
DTH1_k127_549542_8	1288963.ADIS_1441	5.395e-25	112.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,47MTS@768503|Cytophagia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
DTH1_k127_549542_1	761193.Runsl_1002	1.907e-91	302.0	COG3119@1|root,COG3119@2|Bacteria,4PKKW@976|Bacteroidetes,47KTM@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_5506600_4	1433126.BN938_0042	4.022e-24	117.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,22UKP@171550|Rikenellaceae	976|Bacteroidetes	S	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
DTH1_k127_5506600_5	395961.Cyan7425_3030	1.533e-11	72.0	2E1H4@1|root,33JV3@2|Bacteria,1GGCX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5506600_1	1328313.DS2_07733	4.463e-221	693.0	COG2407@1|root,COG2407@2|Bacteria,1R5ZQ@1224|Proteobacteria,1RNGR@1236|Gammaproteobacteria,469P5@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	L-fucose isomerase, C-terminal domain	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
DTH1_k127_5506600_0	1267535.KB906767_gene1403	4.531e-284	906.0	COG3408@1|root,COG3408@2|Bacteria,3Y2YG@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH1_k127_5506600_2	382464.ABSI01000010_gene3476	1.085e-39	160.0	COG0407@1|root,COG5012@1|root,COG0407@2|Bacteria,COG5012@2|Bacteria,46V92@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_5506600_3	665956.HMPREF1032_00855	2.642e-35	141.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24E75@186801|Clostridia,3WPCX@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_5508122_8	298655.KI912266_gene4813	3.03e-07	62.0	COG2801@1|root,COG2801@2|Bacteria,2ITCD@201174|Actinobacteria	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
DTH1_k127_5508122_4	566466.NOR53_2312	1.102e-78	276.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
DTH1_k127_5508122_1	1121447.JONL01000009_gene2551	1.145e-157	521.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2M8H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
DTH1_k127_5508122_0	340177.Cag_1407	2.068e-208	670.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH1_k127_5508122_2	340177.Cag_1408	1.726e-127	430.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
DTH1_k127_5508122_7	118005.AWNK01000004_gene1113	5.416e-19	96.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH1_k127_5508122_5	340177.Cag_0615	1.075e-62	241.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
DTH1_k127_5508122_3	378806.STAUR_2903	2.958e-89	322.0	COG3291@1|root,COG4257@1|root,COG3291@2|Bacteria,COG4257@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
DTH1_k127_5508122_6	102129.Lepto7375DRAFT_5860	8.373e-21	108.0	COG2304@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG4964@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG4964@2|Bacteria,1G54N@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the GSP D family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_552182_19	497964.CfE428DRAFT_4965	8.523e-16	82.0	COG2165@1|root,COG2165@2|Bacteria,46T8M@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH1_k127_552182_15	497964.CfE428DRAFT_6230	1.423e-24	108.0	COG0784@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K01991,ko:K03413	ko02020,ko02026,ko02030,map02020,map02026,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035	1.B.18	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
DTH1_k127_552182_7	1123278.KB893545_gene4805	9.004e-81	293.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,47K8Y@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
DTH1_k127_552182_4	429009.Adeg_0221	8.048e-117	382.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,42F8X@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH1_k127_552182_12	497964.CfE428DRAFT_3441	9.509e-52	189.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
DTH1_k127_552182_3	497964.CfE428DRAFT_3440	2.416e-129	426.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Protein-arginine kinase	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
DTH1_k127_552182_0	1396141.BATP01000059_gene2466	0.0	1015.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DTH1_k127_552182_9	880073.Calab_1235	1.86e-62	228.0	COG0035@1|root,COG0035@2|Bacteria,2NP5M@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
DTH1_k127_552182_10	497964.CfE428DRAFT_3693	2.295e-61	226.0	COG0616@1|root,COG0616@2|Bacteria,46SQ5@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
DTH1_k127_552182_17	696281.Desru_0074	1.038e-18	93.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261Y7@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DTH1_k127_552182_20	661478.OP10G_4100	0.0002177	44.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,VCBS
DTH1_k127_552182_8	497964.CfE428DRAFT_0202	5.804e-69	241.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
DTH1_k127_552182_5	1519464.HY22_06025	9.18e-117	385.0	COG0040@1|root,COG0040@2|Bacteria,1FDU2@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
DTH1_k127_552182_13	497964.CfE428DRAFT_5668	2.825e-46	188.0	COG0457@1|root,COG0457@2|Bacteria,46V4J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_8
DTH1_k127_552182_18	309801.trd_A0913	2.689e-17	87.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
DTH1_k127_552182_1	497964.CfE428DRAFT_0348	7.995e-237	760.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH1_k127_552182_14	452637.Oter_2367	2.665e-36	145.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_552182_11	452637.Oter_1864	3.602e-54	199.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
DTH1_k127_552182_6	452637.Oter_1808	9.2e-84	290.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
DTH1_k127_552182_2	497964.CfE428DRAFT_4940	7.955e-137	440.0	COG1099@1|root,COG1099@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
DTH1_k127_552182_16	497964.CfE428DRAFT_4941	2.012e-22	101.0	2E5PI@1|root,330E7@2|Bacteria,46W49@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5528432_0	886293.Sinac_2434	8.162e-75	257.0	COG2730@1|root,COG3250@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
DTH1_k127_5528432_1	1396418.BATQ01000049_gene432	1.078e-41	170.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_5528432_2	1123508.JH636447_gene7922	7.623e-25	119.0	COG0265@1|root,COG0265@2|Bacteria,2IX93@203682|Planctomycetes	203682|Planctomycetes	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5534376_3	794903.OPIT5_11525	4.338e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,46Z9D@74201|Verrucomicrobia,3K9IE@414999|Opitutae	2|Bacteria	U	Protein of unknown function (DUF1559)	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_5534376_1	452637.Oter_3570	1.997e-25	116.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5534376_0	1396141.BATP01000032_gene4324	2.188e-157	521.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH1_k127_5534376_2	637910.ROD_44971	2.409e-17	86.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,3WZ8G@544|Citrobacter	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
DTH1_k127_553483_3	240016.ABIZ01000001_gene2580	5.608e-39	150.0	2DBKQ@1|root,2Z9U7@2|Bacteria,46XD4@74201|Verrucomicrobia,2IVHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_553483_4	880072.Desac_0616	2.623e-34	145.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
DTH1_k127_553483_0	926550.CLDAP_10330	5.475e-68	238.0	COG0328@1|root,COG0328@2|Bacteria,2G6PS@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
DTH1_k127_553483_2	497964.CfE428DRAFT_5842	1.027e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,46W91@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_553483_6	292415.Tbd_1428	0.0001242	44.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
DTH1_k127_5550301_1	485917.Phep_0675	2.406e-64	229.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
DTH1_k127_5550301_0	1121904.ARBP01000038_gene2566	2.234e-198	637.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
DTH1_k127_5551665_5	1123508.JH636444_gene5158	0.0008381	44.0	COG2165@1|root,COG2165@2|Bacteria,2IZG4@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_5551665_2	1123296.JQKE01000075_gene375	1.698e-37	156.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
DTH1_k127_5551665_4	497964.CfE428DRAFT_0698	9.444e-21	97.0	COG3558@1|root,COG3558@2|Bacteria,46T07@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
DTH1_k127_5551665_3	575609.HMPREF0629_01045	3.334e-22	105.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,22HAS@1570339|Peptoniphilaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH1_k127_5551665_0	1396418.BATQ01000026_gene5276	2.481e-195	614.0	COG0156@1|root,COG0156@2|Bacteria,46SSH@74201|Verrucomicrobia,2ITW1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH1_k127_5551665_1	497964.CfE428DRAFT_4082	1.513e-151	491.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF3472,DUF5077,Gram_pos_anchor,Reprolysin_4
DTH1_k127_5563386_1	530564.Psta_0688	5.177e-134	435.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5563386_2	700598.Niako_5388	2.159e-52	198.0	COG3669@1|root,COG3669@2|Bacteria,4NWP5@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
DTH1_k127_5563386_0	452637.Oter_2229	2.102e-273	871.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
DTH1_k127_5567083_1	395493.BegalDRAFT_2362	7.191e-76	270.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,461AE@72273|Thiotrichales	72273|Thiotrichales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
DTH1_k127_5567083_0	395493.BegalDRAFT_0706	6.828e-90	325.0	COG3210@1|root,COG3210@2|Bacteria,1QMZZ@1224|Proteobacteria,1SG2Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
DTH1_k127_5567083_2	1279009.ADICEAN_00140	2.569e-22	109.0	COG3291@1|root,COG3391@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,47SFQ@768503|Cytophagia	976|Bacteroidetes	O	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB
DTH1_k127_5567230_1	1167006.UWK_00360	5.661e-105	357.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
DTH1_k127_5567230_2	269799.Gmet_1668	8.604e-44	165.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria,43VIR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
DTH1_k127_5567230_0	497964.CfE428DRAFT_6499	8.199e-177	584.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MEDS,PAS_4,PAS_9,Response_reg
DTH1_k127_5567230_3	497964.CfE428DRAFT_0286	5.799e-41	153.0	2DR28@1|root,339V9@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
DTH1_k127_5573407_1	1042375.AFPL01000004_gene651	4.101e-24	106.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,4678W@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363	1.5.1.3	ko:K00287,ko:K18590	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020	DHFR_1
DTH1_k127_5573407_2	742159.HMPREF0004_3321	5.768e-09	64.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,2W0FN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
DTH1_k127_5573407_3	1125700.HMPREF9195_01844	2.118e-06	58.0	2AIAW@1|root,318RT@2|Bacteria,2J6NU@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5573407_0	497964.CfE428DRAFT_6595	1.317e-268	838.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH1_k127_5581042_6	1267535.KB906767_gene950	1.957e-17	84.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria,2JKD5@204432|Acidobacteriia	204432|Acidobacteriia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH1_k127_5581042_2	452637.Oter_0820	9.39e-84	284.0	COG0012@1|root,COG0012@2|Bacteria	2|Bacteria	J	GTP binding	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DTH1_k127_5581042_4	1396141.BATP01000032_gene4325	2.214e-53	199.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5581042_0	1396141.BATP01000032_gene4324	5.084e-219	700.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH1_k127_5581042_3	1403819.BATR01000104_gene3588	5.658e-77	267.0	COG1082@1|root,COG1082@2|Bacteria,46UGG@74201|Verrucomicrobia,2IU3P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_5581042_1	497964.CfE428DRAFT_4945	1.49e-136	447.0	COG1541@1|root,COG1541@2|Bacteria,46SVW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DTH1_k127_5581042_5	497964.CfE428DRAFT_4946	1.65e-28	117.0	2EK8J@1|root,33DYX@2|Bacteria,46VTQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5584804_0	1267533.KB906738_gene2186	2.999e-261	819.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
DTH1_k127_5584804_1	1267533.KB906738_gene2187	1.593e-57	203.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DTH1_k127_5584804_3	889378.Spiaf_1653	4.312e-15	79.0	2EH48@1|root,33AW7@2|Bacteria,2J921@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5584804_2	497964.CfE428DRAFT_4116	6.668e-19	95.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH1_k127_5585944_3	1218084.BBJK01000086_gene5778	0.0004004	53.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
DTH1_k127_5585944_0	1117315.AHCA01000001_gene2142	4.927e-33	148.0	COG3537@1|root,COG5492@1|root,COG3537@2|Bacteria,COG5492@2|Bacteria,1R4VD@1224|Proteobacteria,1RZJ5@1236|Gammaproteobacteria,2Q5IB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH1_k127_5585944_1	1303518.CCALI_02579	8.909e-22	106.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_5585944_2	278957.ABEA03000004_gene4552	6.703e-15	78.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,46Y61@74201|Verrucomicrobia,3K8ZZ@414999|Opitutae	414999|Opitutae	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
DTH1_k127_5596084_3	530564.Psta_2754	4.9e-20	99.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	2|Bacteria	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	SASA
DTH1_k127_5596084_1	583355.Caka_2934	1.529e-126	421.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
DTH1_k127_5596084_0	1492737.FEM08_16470	6.632e-132	434.0	COG1680@1|root,COG1680@2|Bacteria,4P506@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5596084_4	240016.ABIZ01000001_gene4411	1.4e-14	82.0	COG2755@1|root,COG2755@2|Bacteria,46S6X@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Acyl-CoA thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_5596084_2	1123278.KB893574_gene6157	7.709e-87	299.0	COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes,47R5K@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20b
DTH1_k127_5597685_1	452637.Oter_0207	2.808e-131	429.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DTH1_k127_5597685_3	497964.CfE428DRAFT_0506	4.038e-84	286.0	COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DTH1_k127_5597685_9	1410670.JHXF01000006_gene1255	1.959e-16	81.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3WK1D@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH1_k127_5597685_10	754252.PFREUD_06030	3.528e-12	67.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
DTH1_k127_5597685_6	497964.CfE428DRAFT_0508	1.171e-50	182.0	COG0099@1|root,COG0099@2|Bacteria,46STA@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DTH1_k127_5597685_5	497964.CfE428DRAFT_0509	2.446e-55	199.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DTH1_k127_5597685_4	278957.ABEA03000041_gene2061	1.713e-77	265.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,3K7K0@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DTH1_k127_5597685_0	1396141.BATP01000018_gene1517	2.303e-146	470.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,2ITN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DTH1_k127_5597685_8	1156937.MFUM_1030013	1.676e-30	127.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,37GVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
DTH1_k127_5597685_2	1123242.JH636435_gene1577	3.654e-108	371.0	COG0477@1|root,COG0477@2|Bacteria,2J544@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DTH1_k127_5597685_7	1123242.JH636434_gene5469	2.704e-32	128.0	COG2818@1|root,COG2818@2|Bacteria,2IZYU@203682|Planctomycetes	203682|Planctomycetes	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DTH1_k127_5608105_4	1499967.BAYZ01000095_gene4126	4.133e-12	66.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
DTH1_k127_5608105_1	314345.SPV1_00507	3.429e-21	98.0	COG2192@1|root,COG2192@2|Bacteria,1R3MX@1224|Proteobacteria	1224|Proteobacteria	O	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5608105_2	156889.Mmc1_1079	4.79e-17	93.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_5608105_3	1191523.MROS_1643	2.13e-12	69.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5608105_0	497964.CfE428DRAFT_2202	2.316e-37	158.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH1_k127_5608218_0	1123508.JH636439_gene1118	2.55e-183	579.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_5608218_2	402777.KB235903_gene687	4.973e-51	185.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DTH1_k127_5608218_1	880073.Calab_3423	1.577e-156	513.0	COG3525@1|root,COG3525@2|Bacteria,2NNQC@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
DTH1_k127_5637035_0	1403819.BATR01000104_gene3539	8.195e-191	617.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
DTH1_k127_5639128_2	1210884.HG799463_gene9871	8.686e-27	128.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,WD40
DTH1_k127_5639128_1	497964.CfE428DRAFT_0066	7.664e-79	295.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
DTH1_k127_5639128_0	1396418.BATQ01000041_gene6298	1.385e-139	458.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,2IU0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
DTH1_k127_5655226_3	1185876.BN8_06021	6.289e-05	53.0	COG5434@1|root,COG5434@2|Bacteria,4NID5@976|Bacteroidetes,47S55@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
DTH1_k127_5655226_1	1449063.JMLS01000009_gene2209	3.57e-134	454.0	28H6M@1|root,2Z7J0@2|Bacteria	2|Bacteria	G	Pectate lyase	pelY	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase_2
DTH1_k127_5655226_0	497964.CfE428DRAFT_4394	1.187e-213	670.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Beta_helix,F5_F8_type_C,Glyco_hydro_28,Melibiase_2,Pectate_lyase_3
DTH1_k127_5655226_2	525309.HMPREF0494_1039	5.426e-08	58.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,4HC24@91061|Bacilli,3F5KT@33958|Lactobacillaceae	91061|Bacilli	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_5663178_1	1536769.P40081_17515	1.826e-39	154.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H9KJ@91061|Bacilli,26STY@186822|Paenibacillaceae	91061|Bacilli	G	sugar phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_5663178_2	1280947.HY30_08240	4.081e-11	74.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2TR27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_19820	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH1_k127_5663178_0	497964.CfE428DRAFT_5399	3.039e-68	249.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
DTH1_k127_5664446_3	1254432.SCE1572_30435	1.47e-35	136.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH1_k127_5664446_1	504472.Slin_1223	1.893e-107	361.0	COG2755@1|root,COG2755@2|Bacteria,4NIBN@976|Bacteroidetes,47NY7@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_5664446_0	472759.Nhal_2032	2.194e-160	520.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales	135613|Chromatiales	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
DTH1_k127_5664446_4	452637.Oter_1883	3.984e-28	121.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_5664446_2	1122931.AUAE01000004_gene3022	1.227e-97	331.0	COG0383@1|root,COG0383@2|Bacteria,4P1Z7@976|Bacteroidetes,2FTJ7@200643|Bacteroidia	976|Bacteroidetes	G	alpha-mannosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_38,Glyco_hydro_38C
DTH1_k127_5675245_2	1125863.JAFN01000001_gene1123	7.36e-61	218.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DTH1_k127_5675245_3	1396141.BATP01000057_gene2939	2.213e-53	203.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	cqsA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K10915	ko00260,ko00780,ko01100,ko02024,ko05111,map00260,map00780,map01100,map02024,map05111	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding
DTH1_k127_5675245_1	240016.ABIZ01000001_gene2198	1.359e-62	218.0	COG0521@1|root,COG0521@2|Bacteria,46SVJ@74201|Verrucomicrobia,2IUE2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
DTH1_k127_5675245_5	1128421.JAGA01000004_gene2494	5.892e-47	173.0	COG0315@1|root,COG0315@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
DTH1_k127_5675245_4	497964.CfE428DRAFT_2363	9.313e-49	177.0	2DN6W@1|root,32UIF@2|Bacteria,46WNT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5675245_0	497964.CfE428DRAFT_0875	8.793e-77	265.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
DTH1_k127_5676596_2	243090.RB10165	3.082e-30	127.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
DTH1_k127_5676596_0	1150600.ADIARSV_4037	9.637e-132	433.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,1INR1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5676596_1	661478.OP10G_2091	3.416e-79	273.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH1_k127_5680723_1	1210884.HG799466_gene12852	1.785e-18	91.0	COG1520@1|root,COG1520@2|Bacteria,2IX03@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_5680723_2	368408.Tpen_0246	4.01e-11	68.0	COG0182@1|root,arCOG01123@2157|Archaea,2XPZU@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
DTH1_k127_570604_2	1442599.JAAN01000013_gene3669	2.902e-05	50.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1X6Q2@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DTH1_k127_570604_0	497964.CfE428DRAFT_4667	1.5e-179	572.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
DTH1_k127_570604_1	639030.JHVA01000001_gene2022	1.567e-41	163.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
DTH1_k127_570619_4	886293.Sinac_2760	1.269e-15	79.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH1_k127_570619_3	1168034.FH5T_21220	1.123e-82	284.0	COG0667@1|root,COG0667@2|Bacteria,4NP8D@976|Bacteroidetes,2FTGW@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH1_k127_570619_2	204669.Acid345_3213	1.247e-91	307.0	COG0563@1|root,COG0563@2|Bacteria,3Y421@57723|Acidobacteria,2JI14@204432|Acidobacteriia	57723|Acidobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
DTH1_k127_570619_1	661478.OP10G_0366	4.252e-172	548.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH1_k127_570619_0	661478.OP10G_0382	5.976e-284	902.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
DTH1_k127_5727579_4	378806.STAUR_5473	2.385e-11	64.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
DTH1_k127_5727579_3	1197906.CAJQ02000023_gene2158	1.263e-12	80.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2U5ZN@28211|Alphaproteobacteria,3JY4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
DTH1_k127_5727579_2	1279009.ADICEAN_02097	5.095e-33	143.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5727579_0	1123278.KB893448_gene1541	6.089e-192	616.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
DTH1_k127_5727579_1	313590.MED134_09431	6.579e-80	273.0	COG2374@1|root,COG2374@2|Bacteria,4NI8T@976|Bacteroidetes,1I0TH@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH1_k127_5729981_5	497964.CfE428DRAFT_4542	2.341e-120	395.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,DUF4091,Glyco_hydro_71,HYR,Hint_2,Peptidase_C11
DTH1_k127_5729981_1	497964.CfE428DRAFT_2093	9.649e-251	793.0	COG2304@1|root,COG2304@2|Bacteria,46UTA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5729981_0	497964.CfE428DRAFT_4534	1.717e-261	837.0	COG1196@1|root,COG1196@2|Bacteria,46TX7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5729981_6	497964.CfE428DRAFT_4533	6.755e-88	297.0	COG1657@1|root,COG1657@2|Bacteria,46TYK@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH1_k127_5729981_2	497964.CfE428DRAFT_4532	2.32e-159	516.0	COG0737@1|root,COG0737@2|Bacteria,46TFI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
DTH1_k127_5729981_7	794903.OPIT5_25305	2.129e-27	121.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
DTH1_k127_5729981_4	886293.Sinac_2458	2.521e-132	432.0	COG0399@1|root,COG0399@2|Bacteria,2IXZR@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH1_k127_5729981_9	243230.DR_0026	5.101e-09	67.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
DTH1_k127_5729981_3	1236959.BAMT01000001_gene1712	1.338e-154	514.0	COG0515@1|root,COG0515@2|Bacteria,1R6F6@1224|Proteobacteria,2W1UW@28216|Betaproteobacteria,2KKN2@206350|Nitrosomonadales	206350|Nitrosomonadales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
DTH1_k127_5729981_8	240016.ABIZ01000001_gene3798	2.398e-22	111.0	COG0582@1|root,COG0582@2|Bacteria,46T2Q@74201|Verrucomicrobia,2IV0J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DTH1_k127_5739061_0	1267534.KB906755_gene4821	1.278e-176	577.0	COG3345@1|root,COG3345@2|Bacteria,3Y44J@57723|Acidobacteria,2JIVW@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5739061_2	1499967.BAYZ01000095_gene4068	6.264e-18	96.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_5739061_3	1303518.CCALI_02173	3.557e-10	71.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_5739061_1	411479.BACUNI_04071	6.237e-113	390.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH1_k127_5742536_4	1340493.JNIF01000003_gene1731	9.362e-58	206.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH1_k127_5742536_3	1403819.BATR01000092_gene2754	1.43e-131	431.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
DTH1_k127_5742536_6	86106.I862_01655	7.955e-10	69.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,47F1D@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DTH1_k127_5742536_1	1267534.KB906754_gene3770	5.837e-172	554.0	COG1007@1|root,COG1007@2|Bacteria,3Y73U@57723|Acidobacteria,2JMM8@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH1_k127_5742536_0	1267534.KB906754_gene3771	1.004e-224	706.0	COG1008@1|root,COG1008@2|Bacteria,3Y6FA@57723|Acidobacteria,2JM6J@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH1_k127_5742536_2	1267534.KB906754_gene3772	3.93e-147	473.0	COG1008@1|root,COG1008@2|Bacteria,3Y6ZF@57723|Acidobacteria,2JMB1@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH1_k127_5744710_3	1288963.ADIS_1386	4.273e-52	208.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5744710_5	580331.Thit_1725	1.109e-33	150.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,24DCW@186801|Clostridia,42FHF@68295|Thermoanaerobacterales	186801|Clostridia	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
DTH1_k127_5744710_0	452637.Oter_2942	9.573e-204	652.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
DTH1_k127_5744710_4	234267.Acid_6078	1.007e-35	153.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PD40,SdrD_B
DTH1_k127_5744710_1	335543.Sfum_1622	2.646e-130	443.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C554
DTH1_k127_5744710_2	234267.Acid_6081	4.599e-71	254.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,HATPase_c,PKD_3,Reg_prop
DTH1_k127_5749552_3	1296990.H845_3380	9.821e-100	341.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,2JU31@204441|Rhodospirillales	204441|Rhodospirillales	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
DTH1_k127_5749552_6	522306.CAP2UW1_3973	2.814e-13	71.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH1_k127_5749552_1	420324.KI911938_gene9	4.865e-185	607.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,1JXMK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
DTH1_k127_5749552_5	305700.B447_20945	1.459e-58	211.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH1_k127_5749552_2	177437.HRM2_38050	5.299e-138	447.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DTH1_k127_5749552_0	497964.CfE428DRAFT_0990	3.718e-260	822.0	COG0514@1|root,COG0514@2|Bacteria,46S7V@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
DTH1_k127_5749552_4	1304872.JAGC01000003_gene3301	4.27e-69	243.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
DTH1_k127_5749680_4	1403819.BATR01000118_gene4116	8.163e-76	265.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
DTH1_k127_5749680_1	1499967.BAYZ01000093_gene4011	3.751e-160	513.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
DTH1_k127_5749680_2	1166018.FAES_2374	2.049e-119	388.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
DTH1_k127_5749680_6	667014.Thein_1367	3.298e-42	162.0	COG0563@1|root,COG0563@2|Bacteria,2GI9A@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Adenylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	ADK
DTH1_k127_5749680_0	478741.JAFS01000001_gene1962	3.775e-169	551.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,37G93@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH1_k127_5749680_3	1396141.BATP01000060_gene4695	1.082e-98	337.0	COG0546@1|root,COG1051@1|root,COG0546@2|Bacteria,COG1051@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX
DTH1_k127_5749680_7	1132855.KB913035_gene572	2.284e-14	77.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,2KMXM@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
DTH1_k127_5749680_5	1500893.JQNB01000001_gene1609	5.403e-48	177.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1SBBF@1236|Gammaproteobacteria,1XDAF@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH1_k127_5749680_10	864051.BurJ1DRAFT_1395	0.0003976	51.0	2E8G8@1|root,332UI@2|Bacteria,1N7XZ@1224|Proteobacteria,2W3AB@28216|Betaproteobacteria,1KNT8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
DTH1_k127_5749680_8	661478.OP10G_2195	1.506e-05	49.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,T2SSG
DTH1_k127_5755441_0	1210884.HG799464_gene10582	3.788e-133	437.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	mtsE	-	-	ko:K11089	ko05322,map05322	-	-	-	ko00000,ko00001	-	-	-	TROVE,VWA_2
DTH1_k127_5755441_1	1403819.BATR01000181_gene6219	9.28e-56	209.0	COG0583@1|root,COG0583@2|Bacteria,46V82@74201|Verrucomicrobia,2IVST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
DTH1_k127_5755441_4	46234.ANA_C11864	0.0004438	47.0	COG3668@1|root,COG3668@2|Bacteria,1GM0N@1117|Cyanobacteria,1HSNW@1161|Nostocales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
DTH1_k127_5755441_2	1303518.CCALI_00163	3.156e-32	144.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Metallophos
DTH1_k127_5755441_3	1123242.JH636434_gene4912	9.682e-31	126.0	COG1053@1|root,COG1053@2|Bacteria,2J3SP@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
DTH1_k127_576469_0	886293.Sinac_3465	1.097e-168	543.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH1_k127_576469_2	247490.KSU1_C1131	3.111e-57	205.0	COG1881@1|root,COG1881@2|Bacteria,2J1MM@203682|Planctomycetes	203682|Planctomycetes	G	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP,YHYH
DTH1_k127_576469_1	1185876.BN8_01260	5.151e-116	378.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH1_k127_5767044_1	1142394.PSMK_04880	2.471e-14	83.0	COG2165@1|root,COG2165@2|Bacteria,2IY1V@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_5767044_2	521674.Plim_1480	8.029e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,2IYXM@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_5767044_0	1396141.BATP01000033_gene4254	7.242e-188	617.0	COG5434@1|root,COG5434@2|Bacteria,46TEZ@74201|Verrucomicrobia,2IWAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5767044_3	1463820.JOGW01000001_gene5446	1.902e-05	58.0	COG1409@1|root,COG5492@1|root,COG1409@2|Bacteria,COG5492@2|Bacteria,2GKTR@201174|Actinobacteria	201174|Actinobacteria	N	polysaccharide lyase family 8	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Lyase_8,Lyase_8_C,Lyase_8_N
DTH1_k127_5794762_1	1274374.CBLK010000019_gene2757	2.904e-32	143.0	COG1409@1|root,COG3291@1|root,COG3537@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG3537@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,26VY4@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_92
DTH1_k127_5794762_2	489825.LYNGBM3L_19240	3.565e-14	85.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,1G0EK@1117|Cyanobacteria,1H8VS@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act,P_proprotein
DTH1_k127_5794762_0	497964.CfE428DRAFT_0570	3.562e-142	482.0	COG1621@1|root,COG1621@2|Bacteria,46WGP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
DTH1_k127_5794762_3	661478.OP10G_4327	2.983e-08	58.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,DUF4038,DUF5060,F5_F8_type_C,Glyco_hydro_81
DTH1_k127_5797628_2	1128421.JAGA01000003_gene2817	3.591e-75	259.0	COG0596@1|root,COG0596@2|Bacteria,2NQV9@2323|unclassified Bacteria	2|Bacteria	S	Alpha/beta hydrolase family	ybfF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
DTH1_k127_5797628_3	240016.ABIZ01000001_gene5350	4.079e-64	230.0	COG3267@1|root,COG3267@2|Bacteria,46XMZ@74201|Verrucomicrobia,2IW82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
DTH1_k127_5797628_4	240016.ABIZ01000001_gene5349	6.936e-44	183.0	COG1596@1|root,COG3206@1|root,COG1596@2|Bacteria,COG3206@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
DTH1_k127_5797628_0	1123070.KB899258_gene1891	9.653e-88	310.0	COG1596@1|root,COG1596@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
DTH1_k127_5797628_1	240016.ABIZ01000001_gene5347	2.286e-85	295.0	COG1596@1|root,COG1596@2|Bacteria,46XCW@74201|Verrucomicrobia,2IVGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
DTH1_k127_5797628_5	1123070.KB899249_gene319	6.165e-06	53.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,2ITQW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH1_k127_5799434_0	321332.CYB_2140	1.23e-71	276.0	COG2373@1|root,COG2373@2|Bacteria,1G1A1@1117|Cyanobacteria,1H0M9@1129|Synechococcus	1117|Cyanobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,CarboxypepD_reg,MG1,Thiol-ester_cl
DTH1_k127_5809100_1	309807.SRU_1452	1.595e-24	119.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5809100_0	1173026.Glo7428_2698	6.89e-115	402.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH1_k127_5812874_1	497964.CfE428DRAFT_3049	6.55e-152	484.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10559,ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2,Peripla_BP_4
DTH1_k127_5812874_2	497964.CfE428DRAFT_3050	2.634e-130	424.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
DTH1_k127_5812874_0	497964.CfE428DRAFT_3051	1.493e-228	718.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	rbsA	-	3.6.3.17	ko:K10441,ko:K10562	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	ABC_tran,BPD_transp_2
DTH1_k127_5818997_0	240016.ABIZ01000001_gene2256	2.076e-176	583.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
DTH1_k127_5818997_1	497964.CfE428DRAFT_3584	7.654e-174	554.0	COG5441@1|root,COG5441@2|Bacteria,46U7U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
DTH1_k127_5818997_2	545695.TREAZ_3516	6.065e-68	243.0	COG5492@1|root,COG5492@2|Bacteria,2J5ZN@203691|Spirochaetes	203691|Spirochaetes	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
DTH1_k127_5821212_3	1123242.JH636434_gene5340	2.23e-14	82.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH1_k127_5821212_1	452637.Oter_3509	1.878e-88	308.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_5821212_0	595460.RRSWK_06183	1.018e-113	383.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_5821212_2	1168034.FH5T_01570	1.99e-23	109.0	COG3391@1|root,COG3391@2|Bacteria,4PC69@976|Bacteroidetes,2G01G@200643|Bacteroidia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5822124_10	1121406.JAEX01000007_gene2416	1.093e-16	83.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2M8WT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
DTH1_k127_5822124_8	497964.CfE428DRAFT_0221	9.381e-40	155.0	2EKW2@1|root,33EJK@2|Bacteria,46VZV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5822124_5	1403819.BATR01000031_gene1028	6.313e-61	218.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DTH1_k127_5822124_2	1031288.AXAA01000009_gene666	7.818e-168	548.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
DTH1_k127_5822124_3	497964.CfE428DRAFT_4748	8.159e-97	323.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH1_k127_5822124_0	452637.Oter_3558	3.272e-249	776.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH1_k127_5822124_1	1403819.BATR01000125_gene4494	1.799e-180	603.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH1_k127_5822124_6	1396141.BATP01000002_gene4845	9.621e-54	196.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_5822124_4	794903.OPIT5_24610	4.363e-82	286.0	COG0657@1|root,COG0657@2|Bacteria,46UVS@74201|Verrucomicrobia	2|Bacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
DTH1_k127_5822124_9	794903.OPIT5_12525	3.03e-20	100.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_5832729_1	1125863.JAFN01000001_gene972	2.923e-41	162.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
DTH1_k127_5832729_0	472759.Nhal_3844	3.104e-63	224.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1WWQ9@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
DTH1_k127_5832729_2	403833.Pmob_0717	2.976e-32	138.0	COG1597@1|root,COG1597@2|Bacteria,2GCWI@200918|Thermotogae	200918|Thermotogae	I	diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH1_k127_5851962_0	861299.J421_1753	8.856e-259	832.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH1_k127_5851962_1	1123242.JH636434_gene4592	8.903e-17	94.0	COG3712@1|root,COG3712@2|Bacteria,2IZ99@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,Laminin_G_3
DTH1_k127_5851962_2	1121373.KB903632_gene508	1.789e-08	67.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
DTH1_k127_5854035_0	886293.Sinac_0430	1.395e-253	810.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXGT@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
DTH1_k127_5854035_2	1120999.JONM01000010_gene4084	3.848e-80	274.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,2VMCV@28216|Betaproteobacteria,2KSDG@206351|Neisseriales	206351|Neisseriales	P	CutC family	-	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
DTH1_k127_5854035_1	1121403.AUCV01000047_gene1054	2.985e-134	445.0	COG1028@1|root,COG1028@2|Bacteria,1MWC8@1224|Proteobacteria	1224|Proteobacteria	IQ	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5868522_4	452637.Oter_1864	5.239e-09	68.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
DTH1_k127_5868522_5	761193.Runsl_2845	0.0001362	52.0	COG0793@1|root,COG0793@2|Bacteria,4NIGU@976|Bacteroidetes,47RTV@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
DTH1_k127_5868522_2	1122165.AUHS01000032_gene2254	2.436e-23	113.0	2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,1STBF@1236|Gammaproteobacteria,1JD5H@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5868522_1	589865.DaAHT2_0221	2.193e-91	314.0	COG2172@1|root,COG2208@1|root,COG5002@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,1PGCN@1224|Proteobacteria,42ZJ2@68525|delta/epsilon subdivisions,2WUYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
DTH1_k127_5868522_0	330214.NIDE3482	5.065e-219	685.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
DTH1_k127_5873409_2	1123242.JH636434_gene4287	9.805e-51	207.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH1_k127_5873409_1	1403819.BATR01000125_gene4449	8.102e-94	341.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH1_k127_5873409_0	1121904.ARBP01000012_gene1301	1.134e-102	368.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,47MUQ@768503|Cytophagia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5881941_2	1122917.KB899666_gene3406	1.093e-14	80.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.46	ko:K01190,ko:K01202,ko:K12308	ko00052,ko00511,ko00600,ko01100,ko04142,map00052,map00511,map00600,map01100,map04142	-	R01105,R01678,R03355,R03617,R04783,R06114	RC00049,RC00059,RC00451,RC00452	ko00000,ko00001,ko01000	-	GH59	-	Cellulase,DUF4978,Glyco_hydro_42,Glyco_hydro_42M
DTH1_k127_5881941_0	344747.PM8797T_25701	1.072e-153	496.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH1_k127_5881941_1	543728.Vapar_4636	5.783e-105	349.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VM9V@28216|Betaproteobacteria,4ADDA@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Periplasmic binding protein LacI transcriptional regulator	rbsB2	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
DTH1_k127_5901790_2	641112.ACOK01000066_gene116	3.985e-11	77.0	COG5337@1|root,COG5337@2|Bacteria,1UZ0S@1239|Firmicutes,24UMA@186801|Clostridia,3WRYB@541000|Ruminococcaceae	186801|Clostridia	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CotH,Fn3_assoc,LTD
DTH1_k127_5901790_0	1396141.BATP01000034_gene4198	3.038e-167	562.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
DTH1_k127_5901790_1	1232410.KI421412_gene312	2.344e-149	496.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43RY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH1_k127_5903516_1	1121381.JNIV01000084_gene822	1.163e-56	203.0	COG0087@1|root,COG0087@2|Bacteria,1WI2F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DTH1_k127_5903516_2	497964.CfE428DRAFT_0485	1.222e-46	169.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DTH1_k127_5903516_4	382464.ABSI01000005_gene1327	3.348e-17	81.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5903516_0	1122130.AUHN01000008_gene1512	1.493e-59	214.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH1_k127_5903516_6	1301100.HG529244_gene2342	3.268e-08	65.0	COG3103@1|root,COG3807@1|root,COG4193@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,COG4193@2|Bacteria,COG4991@2|Bacteria,1V0NC@1239|Firmicutes,25BAR@186801|Clostridia,36WMT@31979|Clostridiaceae	186801|Clostridia	GT	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
DTH1_k127_5903516_3	1236689.MMALV_01900	3.923e-26	114.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,3F2M9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH1_k127_5903516_5	794903.OPIT5_05255	9.946e-12	74.0	COG0457@1|root,COG1652@1|root,COG0457@2|Bacteria,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
DTH1_k127_5919472_3	1210884.HG799462_gene8241	3.315e-09	59.0	COG1520@1|root,COG1520@2|Bacteria,2J1S1@203682|Planctomycetes	203682|Planctomycetes	P	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_5919472_1	1313301.AUGC01000009_gene1068	2.968e-58	212.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes	976|Bacteroidetes	T	protein tyrosine phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
DTH1_k127_5919472_0	886293.Sinac_3461	1.759e-222	704.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_5919472_2	886293.Sinac_0924	1.862e-36	140.0	COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
DTH1_k127_593621_1	867845.KI911784_gene1741	2.802e-30	127.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,374X2@32061|Chloroflexia	32061|Chloroflexia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
DTH1_k127_593621_2	903818.KI912268_gene3014	4.788e-19	100.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc
DTH1_k127_593621_3	1303518.CCALI_02036	7.49e-14	80.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_593621_0	1317122.ATO12_00675	1.487e-87	300.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2YI4W@290174|Aquimarina	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
DTH1_k127_5954291_0	1396141.BATP01000016_gene2780	0.0	1159.0	COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.5.4.40	ko:K18286,ko:K20276	ko00130,ko01110,ko02024,map00130,map01110,map02024	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_8,Big_5,SLH,SWM_repeat
DTH1_k127_5954291_1	1385935.N836_13145	2.715e-15	92.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5954431_0	489825.LYNGBM3L_30850	1.091e-152	519.0	COG2843@1|root,COG2843@2|Bacteria,1G20Q@1117|Cyanobacteria,1H7BE@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
DTH1_k127_5954431_6	1396141.BATP01000029_gene2242	2.925e-05	58.0	COG1404@1|root,COG1404@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH1_k127_5954431_3	886293.Sinac_2505	1.14e-27	119.0	2ESSA@1|root,33KAQ@2|Bacteria,2J1KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_5954431_2	234267.Acid_6639	4.492e-54	201.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
DTH1_k127_5954431_4	395961.Cyan7425_5164	4.218e-11	69.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH1_k127_5954431_5	640512.BC1003_5144	4.084e-07	53.0	COG1064@1|root,COG1064@2|Bacteria,1P0UC@1224|Proteobacteria,2VPCZ@28216|Betaproteobacteria,1KGVQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_5954431_1	1242864.D187_008109	4.033e-124	407.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42PV7@68525|delta/epsilon subdivisions,2WKXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
DTH1_k127_5954431_7	1242864.D187_001577	0.0001245	54.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria	1224|Proteobacteria	P	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_5964761_0	452637.Oter_0135	9.967e-73	249.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
DTH1_k127_59703_0	1166018.FAES_pFAES01098	2.298e-115	392.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,47KSB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM multicopper oxidase type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH1_k127_5980800_3	595460.RRSWK_02092	3.823e-106	349.0	COG1069@1|root,COG1069@2|Bacteria,2IY2X@203682|Planctomycetes	203682|Planctomycetes	G	FGGY family of carbohydrate kinases, N-terminal domain	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
DTH1_k127_5980800_4	1235797.C816_02559	2.01e-92	310.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,2N6GG@216572|Oscillospiraceae	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
DTH1_k127_5980800_0	234267.Acid_1458	6.716e-141	459.0	COG2017@1|root,COG2017@2|Bacteria,3Y3D2@57723|Acidobacteria	57723|Acidobacteria	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
DTH1_k127_5980800_1	1396141.BATP01000038_gene1209	1.353e-137	444.0	COG1879@1|root,COG1879@2|Bacteria,46XDV@74201|Verrucomicrobia,2IVKX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
DTH1_k127_5980800_2	1123508.JH636443_gene4763	6.651e-122	407.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
DTH1_k127_6005416_0	497964.CfE428DRAFT_3146	1.162e-181	583.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	thiamine pyrophosphate protein TPP binding domain protein	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH1_k127_6005416_2	497964.CfE428DRAFT_3392	5.916e-72	254.0	COG3828@1|root,COG3828@2|Bacteria,46UCF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
DTH1_k127_6005416_1	1303518.CCALI_00783	2.2e-96	337.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_600669_1	1232410.KI421425_gene1538	3.728e-59	211.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
DTH1_k127_600669_0	1232410.KI421425_gene1538	1.829e-166	545.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
DTH1_k127_600669_2	498761.HM1_0138	3.19e-10	72.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
DTH1_k127_601501_3	1096546.WYO_3182	6.639e-22	96.0	COG1943@1|root,COG1943@2|Bacteria,1QKQ4@1224|Proteobacteria,2VBPK@28211|Alphaproteobacteria,1JYW9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH1_k127_601501_1	240016.ABIZ01000001_gene2641	3.595e-33	130.0	COG4842@1|root,COG4842@2|Bacteria,46VM0@74201|Verrucomicrobia,2IVW9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
DTH1_k127_601501_2	497964.CfE428DRAFT_3534	4.695e-29	125.0	2ET52@1|root,33KP5@2|Bacteria,46VY7@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_601501_4	1396141.BATP01000058_gene2012	6.251e-06	51.0	2DD5J@1|root,2ZGMA@2|Bacteria,46WYE@74201|Verrucomicrobia,2IWBI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_601501_0	1403819.BATR01000114_gene3955	1.268e-180	596.0	COG1674@1|root,COG1674@2|Bacteria,46V0I@74201|Verrucomicrobia,2IVES@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	FtsK/SpoIIIE family	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
DTH1_k127_6019607_0	1192034.CAP_5178	7.49e-115	382.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
DTH1_k127_6019607_4	517418.Ctha_2510	7.149e-30	127.0	COG3258@1|root,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3,DUF3365
DTH1_k127_6019607_2	382464.ABSI01000007_gene4118	1.424e-87	294.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH1_k127_6019607_1	240292.Ava_3452	8.085e-99	342.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria,1HME7@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DTH1_k127_6019607_5	246197.MXAN_4314	7.142e-14	76.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2Z1G5@29|Myxococcales	28221|Deltaproteobacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
DTH1_k127_6019607_3	452637.Oter_1623	6.896e-34	131.0	COG0082@1|root,COG0082@2|Bacteria,46SEA@74201|Verrucomicrobia,3K7DA@414999|Opitutae	414999|Opitutae	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DTH1_k127_6020302_0	886293.Sinac_6122	6.017e-217	687.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
DTH1_k127_6020302_4	1042377.AFPJ01000055_gene971	6.057e-07	59.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1S85D@1236|Gammaproteobacteria,468T5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K20988	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
DTH1_k127_6020302_3	700598.Niako_6563	4.666e-08	56.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
DTH1_k127_6020302_1	232348.ADXL01000014_gene730	1.045e-30	123.0	COG4634@1|root,COG4634@2|Bacteria,1G6S3@1117|Cyanobacteria,1H23Q@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6020302_2	278957.ABEA03000095_gene4585	6.473e-13	69.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
DTH1_k127_6048403_2	497964.CfE428DRAFT_2273	1.332e-77	262.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
DTH1_k127_6048403_1	1379698.RBG1_1C00001G0123	3.721e-90	306.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH1_k127_6048403_0	880073.Calab_3201	3.205e-120	395.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
DTH1_k127_6049224_1	485918.Cpin_1862	4.234e-64	223.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IUWM@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
DTH1_k127_6049224_0	1116472.MGMO_20c00270	2.99e-113	380.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1XDKP@135618|Methylococcales	1236|Gammaproteobacteria	C	Tryptophan halogenase	pltM	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
DTH1_k127_6049224_2	671143.DAMO_0701	1.66e-36	150.0	COG0500@1|root,COG2226@2|Bacteria,2NRU8@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
DTH1_k127_6049224_5	998674.ATTE01000001_gene3175	0.0001715	55.0	COG1649@1|root,COG4932@1|root,COG1649@2|Bacteria,COG4932@2|Bacteria,1NP4V@1224|Proteobacteria	1224|Proteobacteria	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
DTH1_k127_6049224_4	160799.PBOR_01905	3.083e-14	87.0	COG1409@1|root,COG3250@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
DTH1_k127_6049224_3	452637.Oter_2184	2.659e-23	116.0	COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae	2|Bacteria	S	SMART Immunoglobulin C2 type	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,Ig_3,VCBS
DTH1_k127_6060107_0	632335.Calkr_2625	1.215e-136	447.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,42F32@68295|Thermoanaerobacterales	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
DTH1_k127_6060107_1	1396418.BATQ01000146_gene3489	6.704e-102	340.0	COG1082@1|root,COG1082@2|Bacteria,46SR1@74201|Verrucomicrobia,2IW0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_6060107_4	1303518.CCALI_01326	3.414e-41	155.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
DTH1_k127_6060107_2	744872.Spica_1339	1.199e-73	256.0	COG0217@1|root,COG0217@2|Bacteria,2J634@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DTH1_k127_6060107_3	1123242.JH636437_gene5953	2.259e-42	170.0	COG4258@1|root,COG4258@2|Bacteria,2IYH7@203682|Planctomycetes	203682|Planctomycetes	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH1_k127_6060869_2	518766.Rmar_1742	1.181e-12	79.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1FJG8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_6060869_1	1396141.BATP01000006_gene5462	7.562e-28	128.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	FecR,Lectin_C,Polyketide_cyc2,VIT,VWA_2,VWA_3
DTH1_k127_6060869_3	1384065.JAGS01000001_gene3122	6.635e-11	74.0	COG2304@1|root,COG4886@1|root,COG2304@2|Bacteria,COG4886@2|Bacteria,1VKTN@1239|Firmicutes	1239|Firmicutes	KLT	Lectin C-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Lectin_C
DTH1_k127_6060869_0	1449063.JMLS01000020_gene5285	9.69e-36	140.0	COG1262@1|root,COG1262@2|Bacteria,1V2AE@1239|Firmicutes,4HFRF@91061|Bacilli,26TF9@186822|Paenibacillaceae	1239|Firmicutes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH1_k127_6062336_0	794903.OPIT5_26140	0.0	1204.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,3K7A5@414999|Opitutae	414999|Opitutae	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH1_k127_6062336_1	448385.sce7733	7.057e-308	954.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
DTH1_k127_6068931_2	439235.Dalk_4465	1.301e-24	109.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2MI2R@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DTH1_k127_6068931_1	497964.CfE428DRAFT_6359	4.632e-121	401.0	COG1104@1|root,COG1104@2|Bacteria,46SFF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH1_k127_6068931_0	344747.PM8797T_24941	6.126e-221	695.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_6068931_3	521674.Plim_0006	8.979e-20	93.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_6089924_0	1210884.HG799464_gene11107	5.778e-44	169.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_6089924_3	452637.Oter_1389	5.972e-05	45.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_6089924_2	452637.Oter_1389	1.358e-16	83.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_6089924_1	237368.SCABRO_03851	2.511e-17	92.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_6095537_1	870187.Thini_0809	1.026e-09	73.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
DTH1_k127_6095537_0	935845.JADQ01000029_gene1230	3.675e-91	341.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
DTH1_k127_6096579_1	1235803.C825_03594	1.564e-31	127.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH1_k127_6096579_0	1288963.ADIS_4732	2.925e-120	392.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH1_k127_6096579_2	886293.Sinac_0062	1.081e-11	65.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
DTH1_k127_613883_4	999541.bgla_2g01540	5.064e-08	62.0	COG2120@1|root,COG2120@2|Bacteria,1NUQU@1224|Proteobacteria,2W27T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DTH1_k127_613883_2	631362.Thi970DRAFT_04074	1.137e-27	120.0	COG2337@1|root,COG2337@2|Bacteria,1NCU5@1224|Proteobacteria,1SDRI@1236|Gammaproteobacteria,1X1EX@135613|Chromatiales	135613|Chromatiales	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
DTH1_k127_613883_3	706587.Desti_3032	8.267e-14	75.0	2EGSU@1|root,33AIY@2|Bacteria,1NKKM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_613883_0	497964.CfE428DRAFT_5010	2.474e-175	561.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_613883_1	530564.Psta_1962	1.856e-94	327.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6156630_0	497964.CfE428DRAFT_5033	5.884e-101	329.0	COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6156630_1	497964.CfE428DRAFT_0111	3.087e-23	117.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6156630_2	886293.Sinac_2826	0.0003484	54.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH1_k127_6175141_3	1121272.KB903272_gene462	3.993e-07	59.0	COG1409@1|root,COG1409@2|Bacteria,2GIT1@201174|Actinobacteria,4DM0J@85008|Micromonosporales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH1_k127_6175141_0	1396418.BATQ01000020_gene5035	3.66e-207	656.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_6175141_1	497964.CfE428DRAFT_1056	4.919e-119	398.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
DTH1_k127_6175141_2	234267.Acid_1623	1.143e-37	144.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
DTH1_k127_6252814_1	1396418.BATQ01000083_gene1173	4.104e-35	154.0	COG0438@1|root,COG0438@2|Bacteria,46ZHN@74201|Verrucomicrobia,2IUVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH1_k127_6252814_0	497964.CfE428DRAFT_0084	1.824e-59	230.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
DTH1_k127_6252814_3	573064.Mefer_0518	2.723e-15	84.0	COG0500@1|root,arCOG04347@2157|Archaea,2Y7Z9@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH1_k127_6252814_2	1499967.BAYZ01000181_gene4493	1.311e-26	112.0	COG0337@1|root,COG0337@2|Bacteria,2NP5Z@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.152,4.2.3.154,4.2.3.4	ko:K01735,ko:K13829,ko:K19969,ko:K21342	ko00400,ko00525,ko01100,ko01110,ko01130,ko01230,map00400,map00525,map01100,map01110,map01130,map01230	M00022,M00814,M00815	R02412,R03083,R10937	RC00002,RC00078,RC00847,RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH1_k127_6253817_3	596152.DesU5LDRAFT_2094	1.25e-07	64.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2M82M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH1_k127_6253817_0	497964.CfE428DRAFT_4864	2.918e-78	270.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6253817_1	221288.JH992901_gene3760	3.405e-68	237.0	COG1247@1|root,COG1247@2|Bacteria,1G8E2@1117|Cyanobacteria	1117|Cyanobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
DTH1_k127_6253817_2	323261.Noc_1851	3.38e-33	132.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1X0HU@135613|Chromatiales	135613|Chromatiales	S	PFAM Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6271022_2	118168.MC7420_2811	2.295e-21	107.0	COG2133@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1G3EW@1117|Cyanobacteria,1HBBU@1150|Oscillatoriales	1117|Cyanobacteria	Q	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8,HemolysinCabind,Laminin_G_3,PKD
DTH1_k127_6271022_1	1403819.BATR01000011_gene418	9.084e-23	111.0	COG2931@1|root,COG5267@1|root,COG2931@2|Bacteria,COG5267@2|Bacteria,46YYY@74201|Verrucomicrobia,2ITXB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH1_k127_6271022_0	1499967.BAYZ01000062_gene6031	2.617e-32	136.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_6274268_1	237368.SCABRO_03600	1.168e-14	78.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6274268_0	497964.CfE428DRAFT_3135	2.272e-166	530.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH1_k127_6281495_9	452637.Oter_2144	2.454e-18	89.0	COG5074@1|root,COG5074@2|Bacteria,46W5A@74201|Verrucomicrobia,3K8CX@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6281495_1	1128421.JAGA01000003_gene2773	1.644e-118	400.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	femD	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH1_k127_6281495_4	1123070.KB899257_gene2284	1.702e-60	216.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,2IU4U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DTH1_k127_6281495_6	382464.ABSI01000021_gene406	7.271e-41	156.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
DTH1_k127_6281495_0	1403819.BATR01000164_gene5622	9.553e-223	711.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
DTH1_k127_6281495_5	198628.Dda3937_00205	1.181e-45	176.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,2JE6U@204037|Dickeya	1236|Gammaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
DTH1_k127_6281495_2	1134413.ANNK01000094_gene900	2.99e-69	252.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,1ZCXK@1386|Bacillus	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH1_k127_6281495_8	1197130.BAFM01000020_gene2812	2.053e-21	108.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVPQ@28890|Euryarchaeota,23TTF@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_6281495_3	1116472.MGMO_10c00180	1.413e-61	220.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1XDRK@135618|Methylococcales	135618|Methylococcales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
DTH1_k127_6281495_7	448385.sce8624	5.145e-29	123.0	COG0318@1|root,COG0318@2|Bacteria,1QXPD@1224|Proteobacteria,43C59@68525|delta/epsilon subdivisions,2WRV5@28221|Deltaproteobacteria,2Z0SY@29|Myxococcales	28221|Deltaproteobacteria	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
DTH1_k127_6286837_0	1121012.AUKX01000016_gene3001	2.001e-150	481.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,1I164@117743|Flavobacteriia,23IAD@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_6286837_1	485917.Phep_3119	2.156e-65	234.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NG20@976|Bacteroidetes,1J03Z@117747|Sphingobacteriia	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
DTH1_k127_6286837_2	1396141.BATP01000028_gene2285	9.595e-41	168.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
DTH1_k127_6286837_3	759362.KVU_2390	0.0009685	48.0	COG2304@1|root,COG2304@2|Bacteria,1RIUR@1224|Proteobacteria,2UB3N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
DTH1_k127_6305666_0	452637.Oter_3478	6.95e-195	612.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
DTH1_k127_6305666_1	1452718.JBOY01000064_gene2578	4.273e-39	166.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	General Secretion Pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	SPOR,Secretin,Secretin_N
DTH1_k127_6311462_1	156889.Mmc1_0977	2.781e-78	272.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
DTH1_k127_6311462_0	497964.CfE428DRAFT_5133	4.995e-281	873.0	COG1164@1|root,COG1164@2|Bacteria,46UYB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
DTH1_k127_6311462_3	203119.Cthe_2878	1.145e-12	79.0	COG3271@1|root,COG3271@2|Bacteria,1VXMN@1239|Firmicutes,251IP@186801|Clostridia,3WPTR@541000|Ruminococcaceae	186801|Clostridia	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
DTH1_k127_6311462_2	700598.Niako_5012	1.041e-35	156.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Amidase_3,ChW,SpoIID
DTH1_k127_6338996_1	1123269.NX02_16050	2.057e-32	135.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CarboxypepD_reg,DUF11,NPCBM_assoc,Peptidase_M66
DTH1_k127_6338996_0	794903.OPIT5_13385	1.733e-195	619.0	COG2271@1|root,COG2271@2|Bacteria,46TJN@74201|Verrucomicrobia,3KA33@414999|Opitutae	74201|Verrucomicrobia	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
DTH1_k127_6339710_10	1042375.AFPL01000004_gene630	3.043e-17	85.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1S39E@1236|Gammaproteobacteria,46837@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG2716 Glycine cleavage system regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_4,ACT_6
DTH1_k127_6339710_12	1210884.HG799464_gene10603	6.822e-14	85.0	2A5PP@1|root,30UEI@2|Bacteria,2J4IH@203682|Planctomycetes	1210884.HG799464_gene10603|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6339710_9	497964.CfE428DRAFT_2283	4.239e-28	117.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH1_k127_6339710_3	1396141.BATP01000003_gene5199	8.261e-171	546.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
DTH1_k127_6339710_5	1396418.BATQ01000136_gene3705	3.452e-91	314.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
DTH1_k127_6339710_6	1051632.TPY_0383	7.052e-56	207.0	COG2912@1|root,COG2912@2|Bacteria,1VXJ8@1239|Firmicutes,25294@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
DTH1_k127_6339710_8	497964.CfE428DRAFT_4835	4.687e-42	157.0	COG4747@1|root,COG4747@2|Bacteria,46WIS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
DTH1_k127_6339710_4	1156844.KB891831_gene4705	3.397e-119	400.0	COG0366@1|root,COG0366@2|Bacteria,2GN52@201174|Actinobacteria	201174|Actinobacteria	G	Alpha amylase catalytic	amyA	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
DTH1_k127_6339710_0	1173027.Mic7113_1425	0.0	2326.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H9JF@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
DTH1_k127_6339710_1	497965.Cyan7822_2990	9.44e-280	865.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,3KJF4@43988|Cyanothece	1117|Cyanobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
DTH1_k127_6339710_14	1379281.AVAG01000028_gene128	2.278e-07	55.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria,431E8@68525|delta/epsilon subdivisions,2WWUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6339710_11	102232.GLO73106DRAFT_00035810	3.747e-15	77.0	COG1724@1|root,COG1724@2|Bacteria,1GAH0@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DTH1_k127_6339710_13	118168.MC7420_7676	2.001e-08	59.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,1H8CN@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
DTH1_k127_6339710_7	349741.Amuc_1517	6.621e-49	182.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
DTH1_k127_6339710_2	1041142.ATTP01000026_gene5081	3.341e-184	589.0	COG0671@1|root,COG0671@2|Bacteria,1R91F@1224|Proteobacteria,2U31R@28211|Alphaproteobacteria,4BCD3@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Acid phosphatase homologues	-	-	3.1.3.2	ko:K09474	ko00740,ko01100,ko02020,map00740,map01100,map02020	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	PAP2
DTH1_k127_6345111_2	794903.OPIT5_09305	2.543e-11	75.0	COG2165@1|root,COG2165@2|Bacteria,46YH2@74201|Verrucomicrobia,3K9K1@414999|Opitutae	414999|Opitutae	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6345111_0	509635.N824_16950	9.184e-70	260.0	28MSZ@1|root,2ZB1A@2|Bacteria,4NHVN@976|Bacteroidetes	976|Bacteroidetes	S	GxGYxY sequence motif in domain of unknown function N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
DTH1_k127_6345111_1	497964.CfE428DRAFT_3506	3.613e-38	153.0	COG4409@1|root,COG4409@2|Bacteria,46SHF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_6347949_1	525904.Tter_1408	1.282e-106	360.0	COG2262@1|root,COG2262@2|Bacteria,2NNWI@2323|unclassified Bacteria	2|Bacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DTH1_k127_6347949_2	1519464.HY22_08455	9.565e-68	235.0	COG0225@1|root,COG0225@2|Bacteria,1FE4X@1090|Chlorobi	1090|Chlorobi	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
DTH1_k127_6347949_0	478741.JAFS01000002_gene146	3.585e-122	411.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,37FVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	tail specific protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
DTH1_k127_6354150_2	313628.LNTAR_07769	7.923e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_6354150_0	497964.CfE428DRAFT_5370	4.297e-110	361.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
DTH1_k127_6395595_3	1396141.BATP01000007_gene5571	1.823e-17	93.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
DTH1_k127_6395595_4	380358.XALC_2323	0.0001815	45.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR3Q@1236|Gammaproteobacteria,1XCRD@135614|Xanthomonadales	135614|Xanthomonadales	L	Isxal7 transposase orfb protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
DTH1_k127_6395595_1	663321.REG_1035	4.953e-76	263.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
DTH1_k127_6395595_0	237609.PSAKL28_31720	7.144e-282	882.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,1RZMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH1_k127_6395595_2	497964.CfE428DRAFT_3367	3.091e-28	117.0	COG3344@1|root,COG3344@2|Bacteria,46UR2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
DTH1_k127_6399403_2	1122135.KB893134_gene3491	3.517e-45	170.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH1_k127_6399403_1	926550.CLDAP_13850	1.44e-129	424.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	2|Bacteria	E	PFAM aminotransferase class V	phnW	GO:0003674,GO:0003824	2.5.1.49,2.6.1.37,3.11.1.1	ko:K01740,ko:K03430,ko:K05306	ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120	-	R00747,R01287,R04152,R04859	RC00008,RC00020,RC00062,RC00368,RC02821,RC02848	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
DTH1_k127_6399403_4	376686.Fjoh_2192	1.488e-09	67.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
DTH1_k127_6399403_3	1403819.BATR01000123_gene4356	8.563e-33	139.0	28KDQ@1|root,2ZA05@2|Bacteria,46VJS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6399403_0	1396141.BATP01000024_gene849	0.0	1751.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
DTH1_k127_6412523_3	452637.Oter_2822	1.708e-29	121.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
DTH1_k127_6412523_2	497964.CfE428DRAFT_1210	2.139e-51	197.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6412523_1	1156937.MFUM_810001	5.112e-189	602.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,37G72@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DTH1_k127_6412523_0	1125863.JAFN01000001_gene34	1.143e-192	624.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DTH1_k127_6412523_4	521045.Kole_0482	9.39e-19	100.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SH3_3
DTH1_k127_6415045_0	497964.CfE428DRAFT_0876	2.508e-126	413.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
DTH1_k127_6415045_1	1396141.BATP01000023_gene745	1.107e-92	310.0	COG1482@1|root,COG1482@2|Bacteria,46SVM@74201|Verrucomicrobia,2IU31@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
DTH1_k127_644801_4	794903.OPIT5_23685	3.158e-12	72.0	COG1820@1|root,COG1820@2|Bacteria,46SRF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DTH1_k127_644801_3	497964.CfE428DRAFT_2661	2.989e-94	315.0	COG1714@1|root,COG1714@2|Bacteria,46UT5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
DTH1_k127_644801_1	439235.Dalk_0975	1.228e-118	392.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2MNT3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
DTH1_k127_644801_0	497964.CfE428DRAFT_2659	9.92e-163	525.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH1_k127_644801_2	497964.CfE428DRAFT_2658	1.634e-107	352.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH1_k127_6469454_1	452637.Oter_0622	9.982e-138	441.0	COG0160@1|root,COG0160@2|Bacteria,46TE8@74201|Verrucomicrobia,3KA3D@414999|Opitutae	2|Bacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	dgdA	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
DTH1_k127_6469454_9	1131269.AQVV01000001_gene1323	7.928e-74	263.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6469454_5	497964.CfE428DRAFT_5470	1.061e-97	334.0	COG2204@1|root,COG2204@2|Bacteria,46VVS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH1_k127_6469454_0	497964.CfE428DRAFT_5468	4.276e-191	620.0	COG5000@1|root,COG5000@2|Bacteria,46THS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH1_k127_6469454_4	382464.ABSI01000020_gene123	1.879e-101	344.0	COG3437@1|root,COG3437@2|Bacteria,46Z3C@74201|Verrucomicrobia,2IUIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
DTH1_k127_6469454_10	402626.Rpic_2975	7.785e-62	231.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VZJ3@28216|Betaproteobacteria,1JZS4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	phcS	-	2.7.13.3	ko:K19621	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH1_k127_6469454_2	382464.ABSI01000020_gene121	7.562e-121	403.0	COG0500@1|root,COG0500@2|Bacteria,46YTR@74201|Verrucomicrobia,2IU3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Response_reg
DTH1_k127_6469454_11	1434929.X946_843	9.907e-58	220.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VNF0@28216|Betaproteobacteria,1K2XK@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Carbohydrate-selective porin, OprB family	oprB	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
DTH1_k127_6469454_13	351348.Maqu_2225	4.439e-32	139.0	COG2898@1|root,COG2898@2|Bacteria,1N1JA@1224|Proteobacteria,1S7E5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2156
DTH1_k127_6469454_8	349521.HCH_05076	2.833e-76	266.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
DTH1_k127_6469454_12	243231.GSU1004	4.07e-44	175.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
DTH1_k127_6469454_6	240016.ABIZ01000001_gene2650	3.144e-97	345.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,2ITQV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
DTH1_k127_6469454_14	111780.Sta7437_2149	1.855e-16	90.0	2CFCI@1|root,32S1P@2|Bacteria,1G4ST@1117|Cyanobacteria,3VJTA@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
DTH1_k127_6469454_3	1158318.ATXC01000001_gene495	1.248e-119	403.0	COG0113@1|root,COG0113@2|Bacteria,2G3MJ@200783|Aquificae	200783|Aquificae	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
DTH1_k127_6469454_15	290397.Adeh_3650	3.967e-12	73.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,BTAD,DUF4242,FHA,Guanylate_cyc,Trans_reg_C
DTH1_k127_6469454_7	926550.CLDAP_16750	8.745e-85	289.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH1_k127_6471464_4	886293.Sinac_7347	8.049e-08	58.0	COG3507@1|root,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6471464_1	1499967.BAYZ01000137_gene111	6.59e-51	191.0	2FGP7@1|root,348IT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6471464_0	1403819.BATR01000104_gene3538	1.949e-87	302.0	COG3618@1|root,COG3618@2|Bacteria,46SN7@74201|Verrucomicrobia,2IUQ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH1_k127_6471464_3	935567.JAES01000033_gene858	1.37e-20	93.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,1SJFZ@1236|Gammaproteobacteria,1X82Y@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6471464_2	1140.Synpcc7942_1288	3.052e-42	162.0	COG3831@1|root,COG3831@2|Bacteria,1GPKY@1117|Cyanobacteria,1H3GN@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF4240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4240
DTH1_k127_6471464_6	497964.CfE428DRAFT_2905	2.443e-05	47.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH1_k127_6494526_2	761193.Runsl_4067	1.92e-67	239.0	COG1082@1|root,COG1082@2|Bacteria,4NFS5@976|Bacteroidetes,47NAA@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
DTH1_k127_6494526_0	886293.Sinac_6980	6.133e-150	489.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_6494526_3	234267.Acid_6615	9.592e-18	95.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6494526_1	679935.Alfi_1534	9.75e-77	277.0	COG0204@1|root,COG2813@1|root,COG4258@1|root,COG0204@2|Bacteria,COG2813@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,2FQP4@200643|Bacteroidia	976|Bacteroidetes	I	Acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
DTH1_k127_6497310_2	452637.Oter_2376	2.012e-59	209.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH1_k127_6497310_3	246197.MXAN_1687	1.278e-31	137.0	2A102@1|root,30P5F@2|Bacteria,1NQ9E@1224|Proteobacteria	1224|Proteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
DTH1_k127_6497310_1	1156937.MFUM_170024	1.714e-87	295.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,37G7G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DTH1_k127_6497310_0	511062.GU3_08515	8.914e-156	502.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1Y3ZI@135624|Aeromonadales	135624|Aeromonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DTH1_k127_6499985_1	530564.Psta_1962	4.893e-33	134.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6499985_4	1120950.KB892753_gene6100	2.551e-13	83.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_39
DTH1_k127_6499985_0	479434.Sthe_1775	3.279e-71	249.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_6499985_3	40571.JOEA01000008_gene2733	3.635e-23	117.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4DXTW@85010|Pseudonocardiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_6499985_2	868131.MSWAN_1282	6.901e-31	131.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH1_k127_6509637_1	497964.CfE428DRAFT_3605	5.011e-157	509.0	COG0364@1|root,COG0364@2|Bacteria,46SHX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
DTH1_k127_6509637_2	1499967.BAYZ01000164_gene6663	3.611e-151	492.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_6509637_0	1123073.KB899241_gene3060	3.826e-193	614.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XDA0@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08137	-	-	-	-	ko00000,ko02000	2.A.1.1.1	-	-	Sugar_tr
DTH1_k127_6509764_0	497964.CfE428DRAFT_0777	4.644e-174	568.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
DTH1_k127_6509764_1	1210884.HG799463_gene9708	5.969e-47	181.0	COG1196@1|root,COG1196@2|Bacteria,2IYCW@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6512504_0	278957.ABEA03000130_gene1701	8.64e-241	754.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
DTH1_k127_6512504_4	278957.ABEA03000130_gene1703	3.322e-94	320.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
DTH1_k127_6512504_6	278957.ABEA03000130_gene1706	1.215e-62	220.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH1_k127_6512504_8	497964.CfE428DRAFT_4274	2.231e-32	130.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
DTH1_k127_6512504_3	497964.CfE428DRAFT_4273	6.93e-107	355.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
DTH1_k127_6512504_5	671143.DAMO_1189	1.807e-92	310.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
DTH1_k127_6512504_1	497964.CfE428DRAFT_4290	3.332e-167	535.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH1_k127_6512504_9	269482.Bcep1808_6245	4.315e-23	101.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
DTH1_k127_6512504_7	1210884.HG799462_gene8243	2.913e-37	156.0	2F56K@1|root,33XTB@2|Bacteria,2J30K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6512504_2	1123242.JH636434_gene4668	1.565e-135	452.0	COG1520@1|root,COG3221@1|root,COG1520@2|Bacteria,COG3221@2|Bacteria,2J1S1@203682|Planctomycetes	203682|Planctomycetes	P	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_6522733_0	272123.Anacy_5162	4.772e-17	96.0	COG0739@1|root,COG2931@1|root,COG0739@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
DTH1_k127_6522733_2	1303518.CCALI_00162	1.977e-13	81.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
DTH1_k127_6522733_1	794903.OPIT5_23755	1.456e-15	76.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DTH1_k127_6535469_1	1396141.BATP01000030_gene3715	1.376e-13	85.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH1_k127_6535469_0	313603.FB2170_10111	6.402e-48	197.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
DTH1_k127_6551534_1	1353531.AZNX01000014_gene3221	3.952e-24	117.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH1_k127_6551534_0	1210884.HG799471_gene14593	2.863e-142	466.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXJQ@203682|Planctomycetes	203682|Planctomycetes	C	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Cytochrom_C
DTH1_k127_6551534_2	1246626.BleG1_3629	5.702e-06	51.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC6I@91061|Bacilli,1ZD0V@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_655627_0	485913.Krac_5916	1.881e-257	804.0	COG0578@1|root,COG0578@2|Bacteria	2|Bacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3,3.1.21.3	ko:K00111,ko:K01153	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000,ko02048	-	-	-	DAO,DAO_C,DUF4145,EcoEI_R_C,FAD_oxidored,HSDR_N,Helicase_C,ResIII
DTH1_k127_655627_1	1288963.ADIS_1960	3.184e-209	676.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Beta_helix,CBM26,CBM_6,CHB_HEX_C_1,CotH,Glyco_hydro_31,YSIRK_signal
DTH1_k127_655627_3	880070.Cycma_3826	1.869e-19	96.0	COG0654@1|root,COG0654@2|Bacteria,4PKHJ@976|Bacteroidetes,47YCY@768503|Cytophagia	976|Bacteroidetes	CH	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH1_k127_655627_4	383372.Rcas_3244	1.653e-07	61.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
DTH1_k127_655627_2	794903.OPIT5_13385	1.144e-26	111.0	COG2271@1|root,COG2271@2|Bacteria,46TJN@74201|Verrucomicrobia,3KA33@414999|Opitutae	74201|Verrucomicrobia	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
DTH1_k127_6558636_0	1469245.JFBG01000044_gene1864	2.564e-60	218.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1WYE1@135613|Chromatiales	135613|Chromatiales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
DTH1_k127_6558636_1	880072.Desac_0729	1.246e-59	226.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MQB5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DTH1_k127_6579263_2	497964.CfE428DRAFT_3745	9.254e-170	543.0	COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	lytB	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
DTH1_k127_6579263_3	497964.CfE428DRAFT_2138	8.042e-89	306.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia	74201|Verrucomicrobia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
DTH1_k127_6579263_4	1121430.JMLG01000021_gene1382	2.866e-56	208.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
DTH1_k127_6579263_0	478741.JAFS01000001_gene1775	6.773e-219	688.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,37FVD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DTH1_k127_6579263_1	1396418.BATQ01000106_gene5285	5.126e-170	548.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,2ITWC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
DTH1_k127_6579263_5	497964.CfE428DRAFT_6239	2.161e-49	178.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
DTH1_k127_6589286_1	404380.Gbem_3420	2.098e-73	253.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,43TDJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH1_k127_6589286_0	234267.Acid_2668	1.001e-111	371.0	COG0407@1|root,COG0407@2|Bacteria,3Y8YA@57723|Acidobacteria	57723|Acidobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_6589286_3	1089547.KB913013_gene3400	3.78e-11	77.0	COG1874@1|root,COG2133@1|root,COG1874@2|Bacteria,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
DTH1_k127_6589286_2	1280390.CBQR020000048_gene957	1.165e-31	144.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
DTH1_k127_6604341_1	370438.PTH_1110	1.415e-22	106.0	COG1388@1|root,COG1388@2|Bacteria,1VJ2T@1239|Firmicutes,24YEF@186801|Clostridia,264FH@186807|Peptococcaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6604341_0	1449063.JMLS01000020_gene5285	1.555e-52	200.0	COG1262@1|root,COG1262@2|Bacteria,1V2AE@1239|Firmicutes,4HFRF@91061|Bacilli,26TF9@186822|Paenibacillaceae	1239|Firmicutes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH1_k127_6604550_2	497964.CfE428DRAFT_0139	2.911e-25	106.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_6604550_0	1123242.JH636434_gene3346	0.0	1189.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_6604550_1	314230.DSM3645_06756	1.176e-85	288.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_6611550_1	1123070.KB899247_gene1500	1.451e-15	79.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6611550_0	886293.Sinac_0668	7.229e-128	419.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH1_k127_6619926_0	481448.Minf_0805	0.0	1345.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,37G3C@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DTH1_k127_6628351_2	240016.ABIZ01000001_gene2058	2.132e-53	194.0	COG0644@1|root,COG0644@2|Bacteria,46U5W@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DTH1_k127_6628351_1	497964.CfE428DRAFT_4864	2.112e-57	208.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6628351_0	886293.Sinac_6489	3.862e-135	461.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
DTH1_k127_6636366_8	378806.STAUR_5237	1.24e-45	184.0	COG0860@1|root,COG0860@2|Bacteria,1NTG0@1224|Proteobacteria,4390F@68525|delta/epsilon subdivisions,2X45H@28221|Deltaproteobacteria,2YYB1@29|Myxococcales	28221|Deltaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
DTH1_k127_6636366_0	1396141.BATP01000032_gene4423	7.899e-286	897.0	COG5297@1|root,COG5297@2|Bacteria,46UD4@74201|Verrucomicrobia,2IVIH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6636366_5	1499967.BAYZ01000095_gene4228	1.211e-74	258.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH1_k127_6636366_9	1156937.MFUM_700051	4.021e-22	107.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,37G1G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
DTH1_k127_6636366_10	867845.KI911784_gene1416	1.39e-05	54.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
DTH1_k127_6636366_2	452637.Oter_2109	9.17e-168	535.0	COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,3K7UW@414999|Opitutae	414999|Opitutae	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DTH1_k127_6636366_6	257314.LJ_0003	1.423e-61	226.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
DTH1_k127_6636366_3	269799.Gmet_1782	5.694e-89	301.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
DTH1_k127_6636366_7	1384056.N787_02850	3.082e-53	203.0	2F24D@1|root,33V2Z@2|Bacteria,1NV0Y@1224|Proteobacteria,1SN7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6636366_1	243233.MCA2119	4.045e-257	799.0	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1XG1U@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
DTH1_k127_6636366_4	1283300.ATXB01000001_gene664	7.197e-79	267.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1XFWC@135618|Methylococcales	135618|Methylococcales	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	hDGE_amylase
DTH1_k127_663671_2	504472.Slin_2839	5.168e-47	176.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_663671_1	452637.Oter_2196	2.125e-189	601.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_663671_0	502025.Hoch_2528	1.305e-206	665.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DTH1_k127_664133_3	1396141.BATP01000025_gene931	9.598e-06	49.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH1_k127_664133_1	649639.Bcell_1282	3.827e-28	120.0	2E58T@1|root,33017@2|Bacteria,1VARJ@1239|Firmicutes,4HKU9@91061|Bacilli,1ZHPC@1386|Bacillus	91061|Bacilli	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
DTH1_k127_664133_0	1303518.CCALI_02909	7.456e-107	360.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
DTH1_k127_664133_2	234267.Acid_0995	4.743e-10	70.0	COG3391@1|root,COG3391@2|Bacteria,3Y7I2@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6652025_4	1396141.BATP01000003_gene4975	8.032e-07	55.0	COG1361@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,46WJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DTH1_k127_6652025_1	1454004.AW11_02365	6.763e-138	455.0	COG3385@1|root,COG3385@2|Bacteria,1RA6A@1224|Proteobacteria,2VUMQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
DTH1_k127_6652025_3	1396141.BATP01000034_gene4147	5.175e-17	88.0	COG3189@1|root,COG3189@2|Bacteria,46VV6@74201|Verrucomicrobia,2IWA9@203494|Verrucomicrobiae	2|Bacteria	S	Protein of unknown function, DUF488	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH1_k127_6652025_0	525904.Tter_0327	5.507e-282	884.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
DTH1_k127_6652025_6	1207075.PputUW4_04220	0.0001286	52.0	COG3708@1|root,COG3708@2|Bacteria,1NBPE@1224|Proteobacteria,1SFP2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
DTH1_k127_6652025_2	481448.Minf_1329	2.832e-19	89.0	COG1449@1|root,COG1449@2|Bacteria,46Z1Y@74201|Verrucomicrobia,37H38@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
DTH1_k127_6665803_2	314230.DSM3645_08622	7.761e-38	153.0	COG3391@1|root,COG3391@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
DTH1_k127_6665803_0	886293.Sinac_2617	2.165e-104	364.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
DTH1_k127_6665803_1	575540.Isop_2740	2.219e-44	174.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
DTH1_k127_6665803_3	240016.ABIZ01000001_gene2409	2.389e-15	79.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,2IUZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
DTH1_k127_6678705_0	497964.CfE428DRAFT_0809	2.109e-202	643.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6678705_6	555088.DealDRAFT_2373	1.396e-21	102.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42K3B@68298|Syntrophomonadaceae	186801|Clostridia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_6678705_3	497964.CfE428DRAFT_0417	5.078e-85	292.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH1_k127_6678705_5	794903.OPIT5_05580	2.242e-24	110.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,3K87P@414999|Opitutae	414999|Opitutae	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
DTH1_k127_6678705_8	661478.OP10G_4109	9.94e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_6678705_4	497964.CfE428DRAFT_5027	1.803e-74	270.0	COG1520@1|root,COG1520@2|Bacteria,46U9S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_6678705_7	756272.Plabr_0281	4.123e-12	76.0	COG4968@1|root,COG4968@2|Bacteria,2J53J@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_6678705_2	945713.IALB_2894	1.788e-113	371.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
DTH1_k127_6678705_1	290397.Adeh_0843	9.588e-137	437.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions,2WM3R@28221|Deltaproteobacteria,2YX6W@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DTH1_k127_6679048_1	1340493.JNIF01000003_gene3916	6.293e-86	302.0	COG2006@1|root,COG2006@2|Bacteria,3Y6M1@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH1_k127_6679048_2	497964.CfE428DRAFT_0699	1.287e-85	301.0	COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,46UKB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DTH1_k127_6679048_0	1403819.BATR01000153_gene5138	1.605e-136	449.0	COG4948@1|root,COG4948@2|Bacteria,46S7G@74201|Verrucomicrobia,2IV9V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6679048_3	1340493.JNIF01000003_gene1832	1.639e-09	58.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
DTH1_k127_6681441_0	1396141.BATP01000034_gene4198	5.494e-19	103.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
DTH1_k127_6681441_1	8364.ENSXETP00000010179	2.396e-10	74.0	2CMMP@1|root,2QQVA@2759|Eukaryota,38DQG@33154|Opisthokonta,3BC84@33208|Metazoa,3CVS6@33213|Bilateria,487IG@7711|Chordata,48ZK4@7742|Vertebrata	33208|Metazoa	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH1_k127_6689520_5	243090.RB3966	1.119e-05	52.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
DTH1_k127_6689520_1	1403819.BATR01000120_gene4247	1.811e-38	155.0	COG3932@1|root,COG3932@2|Bacteria,46T8A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
DTH1_k127_6689520_2	240016.ABIZ01000001_gene760	5.886e-31	137.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like,Usp
DTH1_k127_6689520_3	1089550.ATTH01000001_gene756	3.19e-22	108.0	COG0589@1|root,COG0589@2|Bacteria,4PICI@976|Bacteroidetes,1FK3M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH1_k127_6689520_4	452637.Oter_1439	5.536e-21	98.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
DTH1_k127_6689520_0	1403819.BATR01000124_gene4434	3.647e-86	289.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH1_k127_6693124_4	635013.TherJR_0274	1.646e-17	89.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,261WW@186807|Peptococcaceae	186801|Clostridia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
DTH1_k127_6693124_1	1210884.HG799466_gene12649	2.886e-106	350.0	COG1131@1|root,COG1131@2|Bacteria,2IY1H@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_6693124_3	1123508.JH636441_gene3735	6.306e-89	315.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
DTH1_k127_6693124_0	886293.Sinac_0926	1.363e-212	671.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
DTH1_k127_6693124_6	452637.Oter_1161	1.166e-14	83.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
DTH1_k127_6693124_7	278957.ABEA03000005_gene4419	3.617e-10	65.0	COG5393@1|root,COG5393@2|Bacteria,46XW8@74201|Verrucomicrobia,3K8G8@414999|Opitutae	414999|Opitutae	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
DTH1_k127_6693124_2	382464.ABSI01000013_gene1799	3.642e-105	357.0	COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,2IU82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Divalent cation transporter	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
DTH1_k127_6693124_5	589865.DaAHT2_0949	3.361e-16	81.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
DTH1_k127_6694658_0	1492737.FEM08_22110	2.332e-95	324.0	COG2273@1|root,COG2273@2|Bacteria,4NTIB@976|Bacteroidetes	976|Bacteroidetes	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_67N
DTH1_k127_6698021_1	1125863.JAFN01000001_gene3036	4.501e-58	221.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
DTH1_k127_6698021_0	251221.35213566	6.521e-67	256.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6698021_2	526225.Gobs_3888	2.487e-13	80.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria	201174|Actinobacteria	P	Heavy metal translocating P-type atpase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DTH1_k127_6699684_2	633.DJ40_2401	9.516e-08	54.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,41DMN@629|Yersinia	1236|Gammaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.98.3	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R06895	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403	HemN_C,Radical_SAM
DTH1_k127_6699684_0	1379270.AUXF01000005_gene406	7.788e-112	377.0	COG1232@1|root,COG1232@2|Bacteria,1ZUZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
DTH1_k127_6699684_1	925409.KI911562_gene1437	1.467e-76	263.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1IQ8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
DTH1_k127_6700399_0	382464.ABSI01000013_gene1839	1.727e-97	358.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
DTH1_k127_6700399_3	251221.35213566	8.598e-30	139.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6700399_4	404380.Gbem_1922	1.448e-23	119.0	COG1361@1|root,COG3055@1|root,COG3420@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
DTH1_k127_6700399_1	290397.Adeh_2684	3.757e-41	158.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
DTH1_k127_6700399_2	1396141.BATP01000034_gene4147	5.242e-31	126.0	COG3189@1|root,COG3189@2|Bacteria,46VV6@74201|Verrucomicrobia,2IWA9@203494|Verrucomicrobiae	2|Bacteria	S	Protein of unknown function, DUF488	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH1_k127_6707916_2	1122179.KB890464_gene358	1.075e-13	86.0	COG4733@1|root,COG5295@1|root,COG4733@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Flg_new,He_PIG
DTH1_k127_6707916_1	472759.Nhal_0193	2.706e-114	407.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
DTH1_k127_6707916_0	760192.Halhy_6811	4.224e-140	455.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH1_k127_6707944_1	1231241.Mc24_08639	4.941e-50	195.0	COG0265@1|root,COG0265@2|Bacteria,2GCIH@200918|Thermotogae	200918|Thermotogae	M	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH1_k127_6707944_0	247490.KSU1_C0522	6.227e-94	317.0	COG1131@1|root,COG1131@2|Bacteria,2IX20@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_6707944_2	1192034.CAP_7501	3.452e-25	111.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2Z111@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH1_k127_6709973_6	1283287.KB822578_gene2242	3.994e-21	100.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria,4DNZE@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
DTH1_k127_6709973_0	1123242.JH636436_gene130	7.869e-165	537.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DTH1_k127_6709973_1	1123508.JH636439_gene1318	2.683e-64	237.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
DTH1_k127_6709973_2	1125863.JAFN01000001_gene2967	1.562e-36	143.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
DTH1_k127_6709973_10	745411.B3C1_05932	0.0002703	51.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1J9VA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein	xpsH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
DTH1_k127_6709973_9	1479238.JQMZ01000001_gene267	0.0001671	49.0	COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria,2UK2Q@28211|Alphaproteobacteria,43YW6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NU	General secretion pathway protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
DTH1_k127_6709973_7	1123508.JH636450_gene7091	6.833e-07	60.0	COG4795@1|root,COG4795@2|Bacteria,2J03I@203682|Planctomycetes	203682|Planctomycetes	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH1_k127_6709973_4	1123242.JH636435_gene2166	2.985e-32	143.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
DTH1_k127_6709973_8	1540221.JQNI01000002_gene1751	8.43e-06	58.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DTH1_k127_6709973_5	1121921.KB898712_gene2233	3.839e-23	115.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,2PN33@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
DTH1_k127_6709973_3	661478.OP10G_4206	5.735e-35	146.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
DTH1_k127_6715737_2	1396418.BATQ01000088_gene1036	7.92e-97	327.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
DTH1_k127_6715737_3	1121430.JMLG01000019_gene1656	1.103e-84	297.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
DTH1_k127_6715737_4	497964.CfE428DRAFT_0998	7.179e-52	192.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DTH1_k127_6715737_5	497964.CfE428DRAFT_1520	2.729e-42	158.0	COG0251@1|root,COG0251@2|Bacteria,46T40@74201|Verrucomicrobia	74201|Verrucomicrobia	J	endoribonuclease L-PSP	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Ribonuc_L-PSP
DTH1_k127_6715737_1	1121875.KB907547_gene3471	6.071e-117	393.0	2C20F@1|root,32R9J@2|Bacteria,4P0SP@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
DTH1_k127_6715737_0	497964.CfE428DRAFT_0978	4.17e-122	400.0	COG0165@1|root,COG0165@2|Bacteria,46SCX@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
DTH1_k127_6718396_0	1173027.Mic7113_4161	1.176e-168	588.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
DTH1_k127_6718396_1	402777.KB235898_gene5702	7.954e-11	71.0	COG3291@1|root,COG4675@1|root,COG5276@1|root,COG3291@2|Bacteria,COG4675@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF859,LVIVD,Laminin_G_3
DTH1_k127_6725302_2	1127673.GLIP_1568	5.515e-39	156.0	COG3832@1|root,COG3832@2|Bacteria,1RDGX@1224|Proteobacteria,1S4FQ@1236|Gammaproteobacteria,4675R@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DTH1_k127_6725302_1	794903.OPIT5_23665	8.743e-78	267.0	COG0730@1|root,COG0730@2|Bacteria,46V74@74201|Verrucomicrobia,3K8YW@414999|Opitutae	414999|Opitutae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH1_k127_6725302_0	452637.Oter_0693	1.222e-172	548.0	COG0019@1|root,COG0019@2|Bacteria,46WJD@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH1_k127_6731347_0	429009.Adeg_0173	1.016e-110	373.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH1_k127_6731347_1	497964.CfE428DRAFT_2670	8.939e-66	234.0	COG1562@1|root,COG1562@2|Bacteria,46TVP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Amino_oxidase,SQS_PSY
DTH1_k127_6731347_4	596328.HMPREF0578_1655	3.463e-05	54.0	COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4D3DV@85005|Actinomycetales	201174|Actinobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DTH1_k127_6731347_2	1191523.MROS_1767	1.518e-59	215.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
DTH1_k127_6731347_3	77586.LPERR03G21500.1	3.82e-07	52.0	COG4826@1|root,KOG2392@2759|Eukaryota,37ITN@33090|Viridiplantae,3GFCA@35493|Streptophyta,3KRGS@4447|Liliopsida,3I60N@38820|Poales	35493|Streptophyta	V	Belongs to the serpin family	-	GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044421,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
DTH1_k127_6736354_3	243090.RB3842	2.716e-27	111.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2J2KJ@203682|Planctomycetes	203682|Planctomycetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
DTH1_k127_6736354_0	452637.Oter_3229	4.087e-109	366.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,46TZS@74201|Verrucomicrobia,3K85D@414999|Opitutae	414999|Opitutae	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
DTH1_k127_6736354_1	935837.JAEK01000008_gene3348	9.195e-107	353.0	COG3618@1|root,COG3618@2|Bacteria,1URZE@1239|Firmicutes,4HAYX@91061|Bacilli,1ZG0M@1386|Bacillus	91061|Bacilli	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
DTH1_k127_6736354_2	1121028.ARQE01000007_gene3924	2.944e-86	299.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,2PKKM@255475|Aurantimonadaceae	28211|Alphaproteobacteria	E	Zinc-binding dehydrogenase	-	-	1.1.1.264	ko:K00098	-	-	R05684	RC00089	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_6736354_4	279238.Saro_3424	3.136e-08	59.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TUKJ@28211|Alphaproteobacteria,2K6RN@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH1_k127_6777997_0	497964.CfE428DRAFT_0232	7.78e-217	689.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6782981_0	886293.Sinac_0401	4.692e-192	618.0	COG5426@1|root,COG5426@2|Bacteria,2IWWQ@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
DTH1_k127_6787748_0	240016.ABIZ01000001_gene4315	9.677e-159	520.0	COG1167@1|root,COG1167@2|Bacteria,46STK@74201|Verrucomicrobia,2IVDB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EK	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
DTH1_k127_6787748_1	1403819.BATR01000069_gene2027	3.123e-158	507.0	COG2382@1|root,COG3693@1|root,COG2382@2|Bacteria,COG3693@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH1_k127_6787748_2	886293.Sinac_6937	2.357e-57	202.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_6796308_2	1191523.MROS_2309	4.504e-91	314.0	COG1570@1|root,COG1570@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
DTH1_k127_6796308_1	452637.Oter_2196	5.453e-148	485.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_6796308_4	487796.Flav2ADRAFT_1690	1.265e-40	159.0	COG3291@1|root,COG3291@2|Bacteria,4NH7R@976|Bacteroidetes,1IJC3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_6796308_3	886293.Sinac_4026	1.458e-58	210.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH1_k127_6796308_0	452637.Oter_1389	8.49e-161	522.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_680004_3	243090.RB6850	0.0004167	46.0	COG2165@1|root,COG2165@2|Bacteria,2IWSH@203682|Planctomycetes	203682|Planctomycetes	NU	best DB hits PFAM PF00114	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_680004_1	1123508.JH636446_gene6227	6.337e-06	57.0	COG2165@1|root,COG2165@2|Bacteria,2J1RN@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_680004_2	1121946.AUAX01000016_gene4757	0.0001707	53.0	COG2755@1|root,COG3266@1|root,COG2755@2|Bacteria,COG3266@2|Bacteria,2I2V4@201174|Actinobacteria,4D9Z9@85008|Micromonosporales	201174|Actinobacteria	E	Parallel beta-helix repeats	pelX	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_2,CBM_35,CBM_6
DTH1_k127_680004_0	1110502.TMO_0647	1.521e-33	138.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VEVK@28211|Alphaproteobacteria,2JYN8@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH1_k127_6809112_0	105559.Nwat_1144	4.023e-156	505.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
DTH1_k127_6809112_1	300852.55771566	1.105e-104	354.0	COG0508@1|root,COG0508@2|Bacteria,1WI1G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH1_k127_6809112_5	497964.CfE428DRAFT_6358	5.386e-54	198.0	COG0204@1|root,COG0204@2|Bacteria,46VUC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH1_k127_6809112_7	452637.Oter_3514	4.609e-44	170.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6809112_6	452637.Oter_3514	1.186e-44	171.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6809112_3	240016.ABIZ01000001_gene2631	3.213e-85	302.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH1_k127_6809112_4	5786.XP_003293123.1	6.983e-66	244.0	COG1409@1|root,KOG1378@2759|Eukaryota,3XGP6@554915|Amoebozoa	554915|Amoebozoa	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Pur_ac_phosph_N
DTH1_k127_6809112_10	497964.CfE428DRAFT_2341	3.871e-13	77.0	COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein S18	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DTH1_k127_6809112_9	1353529.M899_0700	1.099e-19	89.0	COG0267@1|root,COG0267@2|Bacteria,1Q1V0@1224|Proteobacteria,437HE@68525|delta/epsilon subdivisions,2MTDQ@213481|Bdellovibrionales,2X2QY@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DTH1_k127_6809112_8	497964.CfE428DRAFT_2343	3.845e-31	130.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
DTH1_k127_6809112_2	497964.CfE428DRAFT_3386	1.872e-104	346.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
DTH1_k127_6812918_2	497964.CfE428DRAFT_1388	2.568e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_6812918_5	497964.CfE428DRAFT_1390	8.943e-20	94.0	2ET1N@1|root,33KJT@2|Bacteria,46TA1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6812918_3	411490.ANACAC_03351	4.425e-47	183.0	COG0371@1|root,COG0371@2|Bacteria,1V994@1239|Firmicutes	1239|Firmicutes	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
DTH1_k127_6812918_0	452637.Oter_1839	1.181e-257	809.0	COG5492@1|root,COG5492@2|Bacteria,46UXF@74201|Verrucomicrobia,3K8Z6@414999|Opitutae	414999|Opitutae	N	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
DTH1_k127_6812918_1	497964.CfE428DRAFT_0138	2.437e-120	392.0	28ND0@1|root,2ZBFU@2|Bacteria,46UZ8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6812918_6	485917.Phep_4007	9.436e-10	72.0	28KZC@1|root,2ZAEP@2|Bacteria,4NITB@976|Bacteroidetes,1IVQJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6834262_0	497964.CfE428DRAFT_4284	3.85e-164	523.0	COG0674@1|root,COG0674@2|Bacteria,46SM9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH1_k127_6834262_3	497964.CfE428DRAFT_4443	2.79e-26	113.0	COG0561@1|root,COG0561@2|Bacteria,46SWT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
DTH1_k127_6834262_1	443143.GM18_2768	5.903e-109	370.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,42X93@68525|delta/epsilon subdivisions,2WSXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
DTH1_k127_6834262_2	879212.DespoDRAFT_02828	1.361e-70	248.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2MPZT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
DTH1_k127_683479_1	583355.Caka_1736	7.89e-117	400.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_683479_0	1210884.HG799465_gene12283	0.0	1038.0	COG0542@1|root,COG0542@2|Bacteria,2IWYZ@203682|Planctomycetes	203682|Planctomycetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DTH1_k127_6847484_2	376686.Fjoh_2456	1.277e-10	76.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6847484_0	1403819.BATR01000069_gene2031	8.673e-40	171.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6847484_1	1403819.BATR01000151_gene5104	1.927e-29	138.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,PATR
DTH1_k127_6855564_2	330214.NIDE0935	5.788e-17	89.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
DTH1_k127_6855564_4	443143.GM18_0916	1.145e-15	84.0	COG2133@1|root,COG4447@1|root,COG4733@1|root,COG2133@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH1_k127_6855564_6	1123276.KB893245_gene1757	8.07e-10	66.0	29Q3N@1|root,30B2B@2|Bacteria,4NPCV@976|Bacteroidetes,47Q0V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6855564_1	794903.OPIT5_27320	2.157e-85	291.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH1_k127_6855564_0	794903.OPIT5_27315	3.757e-115	384.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	MA20_08125	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_trans_aux,MlaD
DTH1_k127_6855564_5	1167006.UWK_00985	2.21e-14	74.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6855564_3	278957.ABEA03000005_gene4416	8.395e-17	81.0	2EK6E@1|root,33DWT@2|Bacteria,46ZJP@74201|Verrucomicrobia,3K8CQ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
DTH1_k127_6892766_0	319795.Dgeo_0730	2.599e-56	199.0	COG0552@1|root,COG0552@2|Bacteria,1WI54@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DTH1_k127_6892766_1	1396141.BATP01000005_gene5990	3.898e-53	192.0	COG4185@1|root,COG4185@2|Bacteria,46XSJ@74201|Verrucomicrobia,2IWH1@203494|Verrucomicrobiae	2|Bacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
DTH1_k127_6892766_2	319795.Dgeo_0730	1.732e-24	105.0	COG0552@1|root,COG0552@2|Bacteria,1WI54@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DTH1_k127_6892766_3	395493.BegalDRAFT_2239	6.763e-17	91.0	COG2755@1|root,COG2755@2|Bacteria,1NUF4@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6892766_4	1550091.JROE01000008_gene3578	3.851e-05	51.0	2DBF9@1|root,2Z8X9@2|Bacteria,4NHC2@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109
DTH1_k127_6897918_3	391600.ABRU01000057_gene394	0.0003039	45.0	COG0464@1|root,COG0464@2|Bacteria,1QZRR@1224|Proteobacteria,2TYD6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	growth	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6897918_2	1188256.BASI01000001_gene341	1.915e-14	82.0	2C2XN@1|root,32GT6@2|Bacteria,1REZE@1224|Proteobacteria,2U8HW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM ERF family protein	-	-	-	-	-	-	-	-	-	-	-	-	ERF
DTH1_k127_6897918_1	1120792.JAFV01000001_gene582	8.825e-19	94.0	2DKVY@1|root,30IDW@2|Bacteria,1RE6Y@1224|Proteobacteria,2U8WV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
DTH1_k127_6900511_0	497964.CfE428DRAFT_3010	2.828e-265	833.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH1_k127_6900511_1	382464.ABSI01000010_gene3213	2.715e-153	496.0	COG0673@1|root,COG0673@2|Bacteria,46UYM@74201|Verrucomicrobia,2IVG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_6900511_2	1396141.BATP01000060_gene4588	6.646e-34	133.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_6910445_0	452637.Oter_3359	1.64e-316	992.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,3K7J2@414999|Opitutae	414999|Opitutae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
DTH1_k127_6934280_3	471854.Dfer_3168	1.138e-18	85.0	COG1082@1|root,COG1082@2|Bacteria,4NFSP@976|Bacteroidetes,47N5G@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_6934280_9	1452536.JARE01000052_gene1721	0.0002819	51.0	2EH4F@1|root,33AWE@2|Bacteria,2I6EJ@201174|Actinobacteria,4FTHX@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6934280_0	575540.Isop_0569	9.228e-206	645.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_6934280_4	880073.Calab_0868	2.783e-14	85.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH1_k127_6934280_8	349741.Amuc_1943	3.513e-05	57.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,2IUR7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
DTH1_k127_6934280_7	111781.Lepto7376_2051	1.804e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1H8XZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
DTH1_k127_6934280_1	478741.JAFS01000001_gene1963	3.678e-107	369.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,37GA0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
DTH1_k127_6934280_2	1396141.BATP01000002_gene4848	2.559e-22	101.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,GSDH,Laminin_G_3,PA14
DTH1_k127_6934280_6	1396141.BATP01000020_gene2	1.014e-10	71.0	COG2755@1|root,COG3317@1|root,COG4409@1|root,COG5267@1|root,COG2755@2|Bacteria,COG3317@2|Bacteria,COG4409@2|Bacteria,COG5267@2|Bacteria,46XM5@74201|Verrucomicrobia,2IW6D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,SASA
DTH1_k127_6934280_5	498761.HM1_0137	7.472e-14	81.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
DTH1_k127_6936164_2	497964.CfE428DRAFT_4346	7.114e-08	62.0	COG2730@1|root,COG2730@2|Bacteria,46UVM@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH1_k127_6936164_0	926569.ANT_25800	4.967e-93	318.0	28KCX@1|root,2Z9ZQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6936164_1	368408.Tpen_1559	4.605e-53	190.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6937299_1	1403819.BATR01000083_gene2420	3.445e-115	373.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,Peptidase_M57
DTH1_k127_6937299_0	497964.CfE428DRAFT_3502	7.924e-286	910.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46THN@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_6937299_2	1168034.FH5T_08245	1.945e-46	176.0	COG0667@1|root,COG0667@2|Bacteria,4PPAM@976|Bacteroidetes,2G14T@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH1_k127_6952417_1	497964.CfE428DRAFT_2087	2.075e-99	332.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia	74201|Verrucomicrobia	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
DTH1_k127_6952417_0	497964.CfE428DRAFT_5324	0.0	1109.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
DTH1_k127_6959688_3	1500893.JQNB01000001_gene2590	8.116e-21	97.0	COG4409@1|root,COG4409@2|Bacteria,1QWFX@1224|Proteobacteria,1T60N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_6959688_1	1499967.BAYZ01000095_gene4068	1.689e-167	535.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_6959688_0	1396141.BATP01000040_gene2191	3.44e-211	666.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_6959688_2	665956.HMPREF1032_00855	2.095e-78	269.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24E75@186801|Clostridia,3WPCX@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_6963077_0	1288963.ADIS_0489	2.561e-250	802.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes	976|Bacteroidetes	G	family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH1_k127_6963077_1	583355.Caka_2934	1.929e-64	228.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
DTH1_k127_6966963_4	1090320.KB900605_gene3525	0.0009778	51.0	COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,2U1SW@28211|Alphaproteobacteria,2K1C6@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
DTH1_k127_6966963_2	679199.HMPREF9332_01395	5.496e-75	284.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
DTH1_k127_6966963_1	497964.CfE428DRAFT_3514	3.002e-116	386.0	COG3055@1|root,COG3055@2|Bacteria,46T14@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6966963_0	1396141.BATP01000009_gene2639	6.807e-208	656.0	COG0477@1|root,COG2814@2|Bacteria,46Z9E@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_6966963_3	1396418.BATQ01000058_gene117	1.531e-73	253.0	COG0329@1|root,COG0329@2|Bacteria,46UHJ@74201|Verrucomicrobia,2IU2T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
DTH1_k127_6967962_3	886293.Sinac_2107	1.44e-40	153.0	COG0329@1|root,COG0329@2|Bacteria,2IYE2@203682|Planctomycetes	203682|Planctomycetes	EM	Dihydrodipicolinate synthase N-acetylneuraminate lyase	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
DTH1_k127_6967962_0	344747.PM8797T_29708	2.794e-179	568.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
DTH1_k127_6967962_1	1396418.BATQ01000150_gene2240	2.879e-173	553.0	COG2942@1|root,COG2942@2|Bacteria,46UIM@74201|Verrucomicrobia,2ITK6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
DTH1_k127_6967962_2	1303518.CCALI_02288	2.939e-45	178.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
DTH1_k127_6978456_6	362418.IW19_23790	1.494e-05	50.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,1I7I9@117743|Flavobacteriia,2NSYV@237|Flavobacterium	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
DTH1_k127_6978456_2	886293.Sinac_4751	4.057e-145	477.0	COG0584@1|root,COG0584@2|Bacteria,2IXVA@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH1_k127_6978456_4	1303518.CCALI_02038	6.815e-16	87.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_6978456_5	1396141.BATP01000007_gene5656	5.584e-07	64.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6978456_3	247490.KSU1_D0514	8.587e-40	173.0	COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14
DTH1_k127_6978456_0	583355.Caka_3109	4.382e-219	744.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
DTH1_k127_6978456_1	1267535.KB906767_gene2459	1.279e-207	659.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,DUF4832,DUF4978,FIVAR,Glyco_hydro_42,Glyco_hydro_42M
DTH1_k127_6981539_2	497964.CfE428DRAFT_4864	1.312e-53	194.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6981539_3	65393.PCC7424_4493	1.259e-31	129.0	COG0680@1|root,COG0680@2|Bacteria,1G7PP@1117|Cyanobacteria,3KI4D@43988|Cyanothece	1117|Cyanobacteria	C	TIGRFAM hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_6981539_1	118005.AWNK01000006_gene1372	2.657e-101	341.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	fas6	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH1_k127_6981539_0	1403819.BATR01000017_gene553	1.114e-107	357.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,46Z8S@74201|Verrucomicrobia,2IWNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM,ThuA
DTH1_k127_6981539_5	530564.Psta_2956	1.653e-05	53.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
DTH1_k127_7015968_1	794903.OPIT5_27630	6.947e-31	125.0	COG0251@1|root,COG0251@2|Bacteria,46V48@74201|Verrucomicrobia,3K8H7@414999|Opitutae	414999|Opitutae	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
DTH1_k127_7015968_0	1122931.AUAE01000028_gene155	2.174e-75	275.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7016789_4	497964.CfE428DRAFT_2928	5.651e-53	194.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DTH1_k127_7016789_6	478741.JAFS01000001_gene1135	1.625e-18	96.0	COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,37GQX@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
DTH1_k127_7016789_1	478741.JAFS01000001_gene1134	2.381e-78	273.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,37GF6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DTH1_k127_7016789_0	1156937.MFUM_1050006	6.106e-87	298.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,37G48@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase family, catalytic domain	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH1_k127_7016789_3	497964.CfE428DRAFT_2933	5.031e-66	243.0	COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DTH1_k127_7016789_2	497964.CfE428DRAFT_2934	1.073e-73	262.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DTH1_k127_7016789_5	1408422.JHYF01000017_gene1849	2.989e-22	101.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	1239|Firmicutes	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
DTH1_k127_7020385_6	1237149.C900_03909	9.683e-37	153.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,4PPUH@976|Bacteroidetes,47YSG@768503|Cytophagia	2|Bacteria	M	domain, Protein	-	-	-	ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,FG-GAP_2,Glug,PKD,SprB
DTH1_k127_7020385_4	429009.Adeg_0968	9.245e-90	315.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
DTH1_k127_7020385_3	639282.DEFDS_0642	1.25e-124	416.0	COG0318@1|root,COG0318@2|Bacteria,2GETC@200930|Deferribacteres	200930|Deferribacteres	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DTH1_k127_7020385_12	1131266.ARWQ01000091_gene18	5.691e-10	63.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7020385_2	497964.CfE428DRAFT_2462	3.82e-145	469.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Nucleoside diphosphate kinase	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DTH1_k127_7020385_7	671143.DAMO_2861	5.67e-35	141.0	COG0494@1|root,COG0494@2|Bacteria,2NPUY@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
DTH1_k127_7020385_0	481448.Minf_0010	5.058e-184	584.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH1_k127_7020385_13	481448.Minf_2089	6.539e-06	57.0	COG1729@1|root,COG1729@2|Bacteria,46ZG7@74201|Verrucomicrobia,37H0Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
DTH1_k127_7020385_1	478741.JAFS01000001_gene2106	5.3e-182	579.0	COG0498@1|root,COG0498@2|Bacteria,46TYU@74201|Verrucomicrobia,37G8J@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH1_k127_7020385_8	316067.Geob_0976	2.749e-31	130.0	28RF4@1|root,2ZDU9@2|Bacteria,1P7NC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7020385_9	638303.Thal_1379	4.527e-30	121.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DTH1_k127_7020385_10	497964.CfE428DRAFT_3331	3.239e-26	111.0	COG1135@1|root,COG1135@2|Bacteria,46WAD@74201|Verrucomicrobia	74201|Verrucomicrobia	P	NIL domain	-	-	-	-	-	-	-	-	-	-	-	-	NIL
DTH1_k127_7020385_11	478741.JAFS01000002_gene623	1.781e-22	101.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,37GUN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
DTH1_k127_7020385_5	926566.Terro_3850	2.092e-43	160.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH1_k127_7038014_5	1227360.C176_10252	2.038e-09	59.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26EKT@186818|Planococcaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DTH1_k127_7038014_3	481448.Minf_0381	4.143e-18	85.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,37GQD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
DTH1_k127_7038014_2	497964.CfE428DRAFT_6142	3.54e-26	117.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
DTH1_k127_7038014_0	497964.CfE428DRAFT_4571	3.753e-69	239.0	COG0632@1|root,COG0632@2|Bacteria,46SZF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DTH1_k127_7038014_1	1123070.KB899248_gene14	1.848e-29	128.0	COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DTH1_k127_7039657_3	1123242.JH636434_gene5260	2.17e-47	175.0	COG4654@1|root,COG4654@2|Bacteria,2J54P@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_7039657_0	1123242.JH636434_gene5259	1.579e-225	706.0	COG3119@1|root,COG3119@2|Bacteria,2IX9P@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_7039657_1	641524.ADICYQ_2511	3.038e-150	488.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
DTH1_k127_7039657_2	387093.SUN_1729	1.448e-56	201.0	COG1943@1|root,COG1943@2|Bacteria,1RF1K@1224|Proteobacteria,42VRT@68525|delta/epsilon subdivisions,2YQZ0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COGs COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DTH1_k127_7059634_2	1123242.JH636435_gene2068	9.707e-08	64.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH1_k127_7059634_0	1123508.JH636444_gene5476	7.691e-195	627.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
DTH1_k127_7059634_1	530564.Psta_4234	5.057e-180	578.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH1_k127_7066320_0	1123242.JH636434_gene3868	2.734e-65	234.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7066320_4	189426.PODO_28355	1.864e-05	51.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,26QNT@186822|Paenibacillaceae	91061|Bacilli	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH1_k127_7066320_1	485917.Phep_1253	2.321e-36	153.0	COG4409@1|root,COG4409@2|Bacteria,4P1PN@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_7066320_2	679926.Mpet_1520	3.634e-26	112.0	arCOG03403@1|root,arCOG03403@2157|Archaea,2Y5T8@28890|Euryarchaeota	28890|Euryarchaeota	K	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DTH1_k127_7071576_1	1173028.ANKO01000017_gene246	3.724e-74	253.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1H82T@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DTH1_k127_7071576_2	313628.LNTAR_17808	2.398e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_7071576_0	234267.Acid_5336	1.597e-108	383.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,3Y3IC@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
DTH1_k127_7071576_3	1123508.JH636439_gene1853	0.0001692	55.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH1_k127_7081207_3	1034769.KB910518_gene1041	0.0001326	51.0	COG1621@1|root,COG3204@1|root,COG3533@1|root,COG3940@1|root,COG1621@2|Bacteria,COG3204@2|Bacteria,COG3533@2|Bacteria,COG3940@2|Bacteria,1U157@1239|Firmicutes,4HT9T@91061|Bacilli,26UV2@186822|Paenibacillaceae	91061|Bacilli	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Laminin_G_3
DTH1_k127_7081207_2	1121101.HMPREF1532_01485	3.614e-07	63.0	COG0860@1|root,COG0860@2|Bacteria,4PPDZ@976|Bacteroidetes,2G15H@200643|Bacteroidia,4ATKG@815|Bacteroidaceae	976|Bacteroidetes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
DTH1_k127_7081207_0	497964.CfE428DRAFT_3199	2.654e-288	893.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DTH1_k127_7081207_1	1303518.CCALI_01797	4.752e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
DTH1_k127_7081646_1	234267.Acid_7084	1.422e-172	543.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
DTH1_k127_7081646_0	1210884.HG799473_gene15021	1.318e-184	586.0	2BXG3@1|root,2Z82R@2|Bacteria,2IXSD@203682|Planctomycetes	203682|Planctomycetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
DTH1_k127_7081646_2	880071.Fleli_3575	0.0005687	52.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,47KPQ@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH1_k127_7085694_4	696747.NIES39_O06680	1.146e-11	76.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DTH1_k127_7085694_2	575540.Isop_2533	2.873e-96	321.0	COG3485@1|root,COG3485@2|Bacteria,2IYK6@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
DTH1_k127_7085694_1	521674.Plim_3842	5.193e-102	340.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
DTH1_k127_7085694_0	497964.CfE428DRAFT_5375	1.864e-247	787.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,46U46@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH1_k127_7085694_5	768670.Calni_0018	0.0005322	49.0	COG0296@1|root,COG0296@2|Bacteria,2GFUK@200930|Deferribacteres	200930|Deferribacteres	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
DTH1_k127_7085694_3	329726.AM1_4632	4.819e-25	111.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
DTH1_k127_7091277_0	1396141.BATP01000060_gene4727	2.455e-195	651.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
DTH1_k127_7095289_0	1121920.AUAU01000009_gene1881	9.122e-15	87.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH1_k127_7100518_3	929562.Emtol_4141	8.615e-34	134.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_7100518_2	886293.Sinac_7126	4.23e-115	384.0	COG1524@1|root,COG1524@2|Bacteria,2IYCV@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH1_k127_7100518_1	452637.Oter_0961	1.326e-153	496.0	COG1171@1|root,COG1171@2|Bacteria,46TW9@74201|Verrucomicrobia,3K73X@414999|Opitutae	414999|Opitutae	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
DTH1_k127_7100518_0	1125863.JAFN01000001_gene1869	2.985e-159	524.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DTH1_k127_7104119_2	240016.ABIZ01000001_gene2409	7.545e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,2IUZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
DTH1_k127_7104119_0	497964.CfE428DRAFT_1198	2.573e-101	334.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
DTH1_k127_7104119_1	330214.NIDE3030	7.969e-56	209.0	COG0859@1|root,COG0859@2|Bacteria,3J0KI@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH1_k127_7104119_3	1396141.BATP01000036_gene3819	1.133e-14	83.0	2EV5U@1|root,33NKM@2|Bacteria,46WDA@74201|Verrucomicrobia,2IUTJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7104583_1	243233.MCA0809	7.024e-138	449.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,1RMRF@1236|Gammaproteobacteria,1XEQV@135618|Methylococcales	135618|Methylococcales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
DTH1_k127_7104583_0	478741.JAFS01000001_gene2129	9.884e-192	625.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,37FUI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
DTH1_k127_7125563_1	497964.CfE428DRAFT_2630	1.055e-95	324.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7125563_2	497964.CfE428DRAFT_2630	6.489e-08	60.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7125563_0	240016.ABIZ01000001_gene3830	3.048e-101	335.0	COG4260@1|root,COG4260@2|Bacteria,46UVR@74201|Verrucomicrobia,2IV4M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17
DTH1_k127_7128367_2	1267535.KB906767_gene3116	6.322e-99	331.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JKYS@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH1_k127_7128367_0	1031288.AXAA01000003_gene1700	8.842e-164	530.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
DTH1_k127_7128367_1	404589.Anae109_0983	3.7e-141	456.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42NZ7@68525|delta/epsilon subdivisions,2WKSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH1_k127_7142723_7	28072.Nos7524_5534	1.961e-05	53.0	COG3511@1|root,COG3511@2|Bacteria,1GHGK@1117|Cyanobacteria,1HRDE@1161|Nostocales	1117|Cyanobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7142723_4	1396141.BATP01000060_gene4563	2.293e-68	252.0	COG0457@1|root,COG0457@2|Bacteria,46W3Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
DTH1_k127_7142723_0	497964.CfE428DRAFT_3048	4.208e-154	497.0	COG1879@1|root,COG1879@2|Bacteria,46TWY@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
DTH1_k127_7142723_8	497964.CfE428DRAFT_5353	0.0009163	43.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH1_k127_7142723_5	886293.Sinac_0846	8.822e-63	228.0	COG0310@1|root,COG0310@2|Bacteria,2IZTS@203682|Planctomycetes	203682|Planctomycetes	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
DTH1_k127_7142723_6	675635.Psed_3353	1.126e-21	103.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria,4E0T6@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
DTH1_k127_7142723_3	886293.Sinac_0844	1.168e-72	252.0	COG1122@1|root,COG1122@2|Bacteria,2IZ47@203682|Planctomycetes	203682|Planctomycetes	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
DTH1_k127_7142723_1	452637.Oter_1576	8.09e-86	295.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,3K7J8@414999|Opitutae	414999|Opitutae	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DTH1_k127_7142723_2	497964.CfE428DRAFT_6711	1.98e-81	284.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
DTH1_k127_715484_1	1396418.BATQ01000041_gene6298	8.743e-34	133.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,2IU0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
DTH1_k127_715484_0	1403819.BATR01000094_gene2931	1.984e-161	515.0	COG1064@1|root,COG1064@2|Bacteria,46UV2@74201|Verrucomicrobia,2IVEY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_715484_2	1396141.BATP01000004_gene5888	1.296e-18	87.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7160213_0	497964.CfE428DRAFT_6615	4.31e-158	506.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
DTH1_k127_7160213_1	530564.Psta_1454	1.905e-139	447.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH1_k127_7160213_3	313612.L8106_06989	1.557e-20	97.0	COG2337@1|root,COG2337@2|Bacteria,1G72T@1117|Cyanobacteria,1HDXS@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DTH1_k127_7160213_4	530564.Psta_1454	3.656e-14	73.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH1_k127_7160213_2	530564.Psta_4484	5.824e-119	394.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_718094_4	880073.Calab_0696	1.231e-22	107.0	COG1262@1|root,COG2911@1|root,COG3055@1|root,COG3934@1|root,COG5492@1|root,COG1262@2|Bacteria,COG2911@2|Bacteria,COG3055@2|Bacteria,COG3934@2|Bacteria,COG5492@2|Bacteria,2NPU7@2323|unclassified Bacteria	2|Bacteria	G	Sulfatase-modifying factor enzyme 1	-	-	3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89	ko:K01176,ko:K01206,ko:K01218,ko:K01219,ko:K01224	ko00051,ko00500,ko00511,ko01100,ko02024,ko04973,map00051,map00500,map00511,map01100,map02024,map04973	-	R01332,R02108,R02112,R11262	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH13,GH26,GH29	-	Big_2,DctA-YdbH,FGE-sulfatase
DTH1_k127_718094_3	998674.ATTE01000001_gene970	3.752e-31	142.0	COG1881@1|root,COG1881@2|Bacteria,1NQK5@1224|Proteobacteria,1S0T6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP,YHYH
DTH1_k127_718094_0	593750.Metfor_1047	8.483e-120	412.0	arCOG09580@1|root,arCOG09580@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_718094_2	382464.ABSI01000007_gene4118	4.148e-86	290.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH1_k127_718094_1	272134.KB731324_gene3229	2.548e-107	365.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DTH1_k127_718094_5	204669.Acid345_0203	1.284e-08	57.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
DTH1_k127_7196032_1	1303518.CCALI_02493	9.535e-09	66.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_7196032_0	1089553.Tph_c09100	1.283e-97	336.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_7208079_1	497964.CfE428DRAFT_4695	3.116e-123	429.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DTH1_k127_7208079_3	247490.KSU1_C0252	0.000449	46.0	2EJYM@1|root,33DP8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7208079_2	391625.PPSIR1_09091	9.497e-12	77.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
DTH1_k127_7208079_0	452637.Oter_2475	3.827e-200	633.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,3K79T@414999|Opitutae	414999|Opitutae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DTH1_k127_7213861_2	1123401.JHYQ01000006_gene6	2.961e-29	126.0	COG1432@1|root,COG1432@2|Bacteria,1REF0@1224|Proteobacteria,1S545@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
DTH1_k127_7213861_1	404589.Anae109_3433	4.383e-99	336.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH1_k127_7213861_0	429009.Adeg_1724	2.547e-123	405.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH1_k127_7213861_3	215803.DB30_7168	2.272e-18	96.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
DTH1_k127_7213861_4	102125.Xen7305DRAFT_00008790	4.08e-08	59.0	2CRRJ@1|root,32SPH@2|Bacteria,1GGJ1@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
DTH1_k127_721710_0	886293.Sinac_3213	3.157e-210	665.0	COG4805@1|root,COG4805@2|Bacteria,2IXQZ@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DTH1_k127_721710_1	240016.ABIZ01000001_gene4797	8.611e-163	527.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH1_k127_721710_2	240016.ABIZ01000001_gene4794	5.389e-128	419.0	COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia,2ITPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH1_k127_7229377_0	370438.PTH_0469	3.22e-73	259.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
DTH1_k127_7229377_1	368408.Tpen_1559	4.952e-54	203.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7237464_3	457570.Nther_0516	1.925e-29	128.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DTH1_k127_7237464_1	1123070.KB899252_gene961	1.21e-155	497.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DTH1_k127_7237464_0	497964.CfE428DRAFT_1447	0.0	1159.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
DTH1_k127_7237464_5	180281.CPCC7001_1993	2.53e-13	72.0	COG0732@1|root,COG0732@2|Bacteria,1G6EU@1117|Cyanobacteria,22TSW@167375|Cyanobium	1117|Cyanobacteria	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
DTH1_k127_7237464_7	1078085.HMPREF1210_01122	3.4e-05	54.0	2DDVZ@1|root,2ZJI2@2|Bacteria,1W5EF@1239|Firmicutes,4I14U@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7237464_4	1042209.HK44_027725	2.055e-15	78.0	COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,1S29W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0732 Restriction endonuclease S subunits	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
DTH1_k127_7237464_2	1396141.BATP01000025_gene931	8.842e-77	271.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH1_k127_7237464_6	589865.DaAHT2_1405	1.248e-05	50.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MM6V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DTH1_k127_7244146_0	497964.CfE428DRAFT_1084	5.379e-256	807.0	COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
DTH1_k127_7244146_1	234267.Acid_6938	1.153e-150	488.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria	57723|Acidobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
DTH1_k127_7244146_2	452637.Oter_1760	6.265e-43	163.0	COG1057@1|root,COG1057@2|Bacteria,46T27@74201|Verrucomicrobia,3K85U@414999|Opitutae	414999|Opitutae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH1_k127_7244146_3	1283299.AUKG01000005_gene41	2.02e-28	119.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CQDN@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
DTH1_k127_7244146_4	1156937.MFUM_200030	6.367e-20	93.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,37HAT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	PurA ssDNA and RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PurA
DTH1_k127_7244219_1	373994.Riv7116_3284	1.251e-65	236.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	elrF	-	-	-	-	-	-	-	-	-	-	-	Cutinase,DUF1350,DUF1631
DTH1_k127_7244219_2	240016.ABIZ01000001_gene54	5.171e-18	85.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH1_k127_7244219_0	926550.CLDAP_30260	1.353e-100	355.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
DTH1_k127_7244641_1	595460.RRSWK_04029	0.0001548	46.0	COG4977@1|root,COG4977@2|Bacteria,2J536@203682|Planctomycetes	2|Bacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
DTH1_k127_7244641_0	1288963.ADIS_3575	1.625e-154	505.0	COG1470@1|root,COG1470@2|Bacteria,4NF75@976|Bacteroidetes	976|Bacteroidetes	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7256479_1	452637.Oter_1999	9.948e-06	59.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
DTH1_k127_7256479_0	760192.Halhy_4220	3.339e-66	250.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes	976|Bacteroidetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
DTH1_k127_7314623_1	221288.JH992901_gene992	2.47e-53	197.0	COG0583@1|root,COG0583@2|Bacteria,1G8J2@1117|Cyanobacteria,1JK83@1189|Stigonemataceae	1117|Cyanobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
DTH1_k127_7314623_2	1123368.AUIS01000009_gene2446	4.84e-33	133.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,1S205@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	redox protein regulator of disulfide bond formation	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
DTH1_k127_7314623_4	1123070.KB899266_gene2496	2.525e-11	68.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
DTH1_k127_7314623_3	481448.Minf_2177	1.195e-31	126.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DTH1_k127_7314623_0	452637.Oter_2054	8.663e-108	352.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH1_k127_731616_1	904296.HMPREF9124_0631	9.727e-35	153.0	28J61@1|root,2Z91S@2|Bacteria,1UYHJ@1239|Firmicutes,24EVG@186801|Clostridia,2PS0Q@265975|Oribacterium	186801|Clostridia	S	Endo-alpha-N-acetylgalactosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_101,Glyco_hydro_129
DTH1_k127_731616_0	1235803.C825_00157	1.036e-54	196.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
DTH1_k127_7347288_0	1396141.BATP01000034_gene4198	6.803e-139	465.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
DTH1_k127_7360165_0	497964.CfE428DRAFT_1215	1.571e-95	317.0	COG1100@1|root,COG1100@2|Bacteria,46VDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	Arf
DTH1_k127_7360165_2	497964.CfE428DRAFT_1216	8.747e-31	127.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
DTH1_k127_7360165_4	1312959.KI914674_gene3398	5.096e-06	60.0	COG3087@1|root,COG3291@1|root,COG3087@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Laminin_G_3,PKD
DTH1_k127_7360165_1	1396141.BATP01000060_gene4657	1.815e-39	169.0	COG2010@1|root,COG2312@1|root,COG3204@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD,Laminin_G_3
DTH1_k127_7366050_0	864702.OsccyDRAFT_2745	1.314e-131	477.0	COG2931@1|root,COG2931@2|Bacteria,1GHDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH1_k127_7374847_0	304371.MCP_2061	0.0009174	51.0	COG0457@1|root,arCOG02497@1|root,arCOG02497@2157|Archaea,arCOG03032@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	Beta_helix,TPR_16,TPR_19
DTH1_k127_7408123_0	481448.Minf_0686	4.561e-109	359.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,37FZV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DTH1_k127_7408123_10	794903.OPIT5_02410	8.864e-35	134.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,3K87G@414999|Opitutae	414999|Opitutae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DTH1_k127_7408123_14	497964.CfE428DRAFT_0492	1.696e-23	105.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia	74201|Verrucomicrobia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DTH1_k127_7408123_1	452637.Oter_0220	5.641e-87	298.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DTH1_k127_7408123_6	497964.CfE428DRAFT_0494	4.228e-54	193.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DTH1_k127_7408123_16	349741.Amuc_0295	0.0001941	51.0	COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia,2IUWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L29 protein	-	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DTH1_k127_7408123_13	1403819.BATR01000164_gene5565	1.51e-26	111.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,2IUPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DTH1_k127_7408123_8	1156937.MFUM_870033	8.151e-47	171.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,37GRN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DTH1_k127_7408123_15	382464.ABSI01000011_gene2659	3.926e-23	101.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DTH1_k127_7408123_3	649743.HMPREF0972_01639	3.564e-60	213.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4D3F1@85005|Actinomycetales	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DTH1_k127_7408123_11	1403819.BATR01000162_gene5349	2.62e-31	124.0	COG0199@1|root,COG0199@2|Bacteria,46TBH@74201|Verrucomicrobia,2IUM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DTH1_k127_7408123_9	265311.Mfl137	3.903e-40	152.0	COG0096@1|root,COG0096@2|Bacteria,3WTD8@544448|Tenericutes	544448|Tenericutes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DTH1_k127_7408123_2	240016.ABIZ01000001_gene4064	9.286e-68	234.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,2IU69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DTH1_k127_7408123_12	771875.Ferpe_1400	1.86e-28	119.0	COG0256@1|root,COG0256@2|Bacteria,2GD32@200918|Thermotogae	200918|Thermotogae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
DTH1_k127_7408123_4	497964.CfE428DRAFT_0503	6.899e-57	205.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DTH1_k127_7408123_7	497964.CfE428DRAFT_0504	5.387e-49	179.0	COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DTH1_k127_7408123_5	478741.JAFS01000001_gene1597	3.509e-54	196.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,37GAI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DTH1_k127_7408683_1	1303518.CCALI_00782	7.452e-70	250.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
DTH1_k127_7408683_0	1303518.CCALI_00781	7.45e-72	255.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE_1	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH1_k127_7408683_2	1396418.BATQ01000046_gene6161	1.46e-35	146.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH1_k127_7412748_3	357808.RoseRS_4080	8.817e-10	66.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_31
DTH1_k127_7412748_1	497964.CfE428DRAFT_0568	3.548e-61	217.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DTH1_k127_7412748_0	1123248.KB893385_gene4912	5.064e-177	557.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7412748_2	1396418.BATQ01000142_gene3260	1.471e-11	65.0	COG2120@1|root,COG2120@2|Bacteria,46SP2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DTH1_k127_7413566_0	1242864.D187_002616	1.829e-64	227.0	COG3507@1|root,COG3537@1|root,COG3507@2|Bacteria,COG3537@2|Bacteria,1R5VX@1224|Proteobacteria	1224|Proteobacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7413566_1	1396141.BATP01000047_gene3984	7.165e-33	145.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH1_k127_7418538_7	1385521.N803_04655	3.254e-33	136.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4FF2H@85021|Intrasporangiaceae	201174|Actinobacteria	H	molybdopterin	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DTH1_k127_7418538_1	944480.ATUV01000001_gene1378	2.606e-160	523.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
DTH1_k127_7418538_2	595460.RRSWK_04461	1.975e-147	479.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_7418538_8	671143.DAMO_0994	3.938e-29	124.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_7418538_4	523841.HFX_0260	5.664e-53	200.0	COG0421@1|root,COG0477@1|root,arCOG00050@2157|Archaea,arCOG02682@2157|Archaea,2XUEJ@28890|Euryarchaeota,23T1E@183963|Halobacteria	183963|Halobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
DTH1_k127_7418538_9	635013.TherJR_1799	1.891e-26	116.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
DTH1_k127_7418538_0	1396141.BATP01000030_gene3783	5.231e-313	974.0	28I74@1|root,2Z8A0@2|Bacteria,46TG0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7418538_5	479437.Elen_2127	1.429e-40	157.0	COG0330@1|root,COG0330@2|Bacteria,2GM0Z@201174|Actinobacteria,4CUCE@84998|Coriobacteriia	84998|Coriobacteriia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH1_k127_7420805_0	706587.Desti_1943	2.71e-116	377.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,42NEF@68525|delta/epsilon subdivisions,2WIVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
DTH1_k127_7420805_1	1283284.AZUK01000001_gene812	2.038e-98	328.0	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,1RU3S@1236|Gammaproteobacteria,1Y501@135624|Aeromonadales	135624|Aeromonadales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
DTH1_k127_7420805_3	1396141.BATP01000047_gene3930	2.655e-64	225.0	COG3476@1|root,COG3476@2|Bacteria,46SXT@74201|Verrucomicrobia,2IVZD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	TspO/MBR family	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
DTH1_k127_7420805_4	517417.Cpar_1952	1.887e-28	117.0	COG0702@1|root,COG0702@2|Bacteria,1FE8P@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
DTH1_k127_7420805_2	1158182.KB905020_gene2164	9.171e-66	229.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1WXQX@135613|Chromatiales	135613|Chromatiales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DTH1_k127_7432608_8	278957.ABEA03000195_gene475	6.338e-28	122.0	COG2165@1|root,COG2165@2|Bacteria,46X23@74201|Verrucomicrobia,3K9EQ@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_7432608_11	313606.M23134_01193	5.16e-13	82.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
DTH1_k127_7432608_10	649831.L083_3819	7.867e-19	101.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7432608_1	489825.LYNGBM3L_21200	5.408e-138	462.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH1_k127_7432608_2	335543.Sfum_3555	7.66e-138	463.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2MSIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH1_k127_7432608_5	1173026.Glo7428_0927	3.521e-39	154.0	COG0110@1|root,COG0110@2|Bacteria,1G9TY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
DTH1_k127_7432608_6	497964.CfE428DRAFT_2920	5.596e-39	153.0	COG0110@1|root,COG0110@2|Bacteria,46T6H@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH1_k127_7432608_0	335543.Sfum_3551	2.9e-178	565.0	COG0438@1|root,COG0438@2|Bacteria,1RAGT@1224|Proteobacteria,42Y8X@68525|delta/epsilon subdivisions,2WU97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7432608_7	1449976.KALB_4422	3.24e-33	143.0	COG0500@1|root,COG0500@2|Bacteria,2INXQ@201174|Actinobacteria,4EDFK@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DTH1_k127_7432608_3	489825.LYNGBM3L_21170	5.811e-136	443.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH1_k127_7432608_4	251229.Chro_0879	1.244e-70	252.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,3VKAC@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH1_k127_7432608_9	335541.Swol_2445	1.553e-23	104.0	COG2120@1|root,COG2120@2|Bacteria,1TUFP@1239|Firmicutes,25PKR@186801|Clostridia,42KY4@68298|Syntrophomonadaceae	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DTH1_k127_744143_0	509635.N824_15295	1.397e-123	422.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,1IVFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_744143_1	595460.RRSWK_00437	2.247e-38	146.0	COG1874@1|root,COG1874@2|Bacteria,2J2PX@203682|Planctomycetes	203682|Planctomycetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7451921_0	886293.Sinac_6954	3.629e-276	881.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH1_k127_7451921_1	886293.Sinac_5601	2.81e-146	479.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_7477757_1	1122925.KB895378_gene2565	2.45e-11	78.0	COG0383@1|root,COG1409@1|root,COG3537@1|root,COG3693@1|root,COG0383@2|Bacteria,COG1409@2|Bacteria,COG3537@2|Bacteria,COG3693@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,26VY4@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,Glyco_hydro_92
DTH1_k127_7477757_0	1396141.BATP01000043_gene1929	2.307e-85	321.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_7513499_0	1210884.HG799464_gene10641	9.547e-112	399.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPU@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
DTH1_k127_7513499_1	530564.Psta_4257	1.716e-68	265.0	COG2755@1|root,COG5306@1|root,COG2755@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
DTH1_k127_7519288_1	497964.CfE428DRAFT_6114	4.96e-126	429.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
DTH1_k127_7519288_2	794903.OPIT5_22505	1.179e-07	63.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia,3K89I@414999|Opitutae	414999|Opitutae	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
DTH1_k127_7519288_3	191610.CATYP_00200	0.0002279	49.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,22M4R@1653|Corynebacteriaceae	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
DTH1_k127_7519288_0	518766.Rmar_1873	1.172e-176	570.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1FIKP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DTH1_k127_7536510_0	886293.Sinac_5628	8.856e-107	354.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,2IX68@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_7536510_1	1499967.BAYZ01000089_gene5015	3.356e-82	280.0	COG1212@1|root,COG1212@2|Bacteria,2NP8R@2323|unclassified Bacteria	2|Bacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DTH1_k127_7536510_3	265072.Mfla_2506	1.308e-48	188.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KMRM@206350|Nitrosomonadales	206350|Nitrosomonadales	FG	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
DTH1_k127_7536510_2	469381.Dpep_0241	1.165e-68	247.0	COG0043@1|root,COG0043@2|Bacteria,3T9U4@508458|Synergistetes	508458|Synergistetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7539906_0	497964.CfE428DRAFT_4943	4.046e-67	238.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
DTH1_k127_7539906_3	756272.Plabr_3146	1.878e-13	80.0	COG5492@1|root,COG5492@2|Bacteria,2IYV9@203682|Planctomycetes	203682|Planctomycetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
DTH1_k127_7539906_2	497964.CfE428DRAFT_5026	1.42e-53	199.0	2DXTF@1|root,346G5@2|Bacteria,46W16@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7539906_1	555779.Dthio_PD1816	7.028e-61	221.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,2MGTS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
DTH1_k127_7539906_4	575540.Isop_0345	0.0007178	45.0	COG1167@1|root,COG1167@2|Bacteria,2IY9J@203682|Planctomycetes	203682|Planctomycetes	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
DTH1_k127_756344_1	1123508.JH636441_gene3126	7.619e-89	298.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_756344_2	1173027.Mic7113_4586	1.944e-40	157.0	COG4636@1|root,COG4636@2|Bacteria,1G2P0@1117|Cyanobacteria,1H6WC@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DTH1_k127_756344_0	452637.Oter_3559	1.348e-171	548.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
DTH1_k127_7567776_1	710696.Intca_1127	1.195e-26	125.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
DTH1_k127_7567776_0	497964.CfE428DRAFT_5484	4.576e-93	318.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH1_k127_758500_1	1120999.JONM01000002_gene700	1.247e-100	340.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VIYI@28216|Betaproteobacteria,2KSJR@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH1_k127_758500_0	684949.ATTJ01000001_gene2613	1.802e-114	383.0	COG3842@1|root,COG3842@2|Bacteria,1WIWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
DTH1_k127_758500_2	321327.CYA_1858	1.491e-87	298.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,1H1QV@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
DTH1_k127_758500_3	321332.CYB_2209	1.378e-49	185.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria,1H1XK@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
DTH1_k127_7602082_2	1303518.CCALI_00340	2.432e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH1_k127_7602082_0	861299.J421_6202	4.704e-128	424.0	COG1064@1|root,COG1064@2|Bacteria,1ZSXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_7602082_1	1303518.CCALI_02638	6.018e-16	87.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_7613130_0	1122176.KB903598_gene4712	2.354e-118	410.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
DTH1_k127_7613130_1	526227.Mesil_3282	8.112e-11	68.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	PIN
DTH1_k127_7627356_2	452637.Oter_0554	3.488e-190	605.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
DTH1_k127_7627356_0	1396141.BATP01000042_gene1909	1.984e-248	785.0	COG3829@1|root,COG3829@2|Bacteria,46UZT@74201|Verrucomicrobia,2IVHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
DTH1_k127_7627356_4	1396141.BATP01000042_gene1908	3.297e-84	283.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DTH1_k127_7627356_3	1396418.BATQ01000092_gene5859	3.807e-104	349.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
DTH1_k127_7627356_6	1385518.N798_14125	1.37e-34	137.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4FH30@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DTH1_k127_7627356_1	314230.DSM3645_26339	6.275e-194	614.0	COG2755@1|root,COG2755@2|Bacteria,2IYT9@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Lipase_GDSL_2
DTH1_k127_7627356_7	469383.Cwoe_4336	6.301e-09	65.0	2B4AG@1|root,31X1X@2|Bacteria,2GWKS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7627356_5	1121335.Clst_0783	2.31e-36	138.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
DTH1_k127_762772_3	1395587.P364_0117575	4.59e-26	116.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_762772_1	240016.ABIZ01000001_gene1086	2.043e-89	300.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,2IU40@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH1_k127_762772_0	382464.ABSI01000011_gene2675	8.562e-116	391.0	COG2610@1|root,COG2610@2|Bacteria,46UQS@74201|Verrucomicrobia,2IVYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
DTH1_k127_762772_2	1123508.JH636439_gene1058	1.047e-49	186.0	COG4221@1|root,COG4221@2|Bacteria,2IYVR@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH1_k127_7635659_2	497964.CfE428DRAFT_5350	7.438e-47	172.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH1_k127_7635659_1	1403819.BATR01000042_gene1250	1.032e-99	337.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_7635659_3	1366050.N234_08390	1.466e-28	122.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria,1K7HV@119060|Burkholderiaceae	2|Bacteria	E	ACT domain	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_6,Homoserine_dh,NAD_binding_3
DTH1_k127_7635659_0	497964.CfE428DRAFT_0788	1.128e-227	710.0	COG0362@1|root,COG0362@2|Bacteria,46SDE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
DTH1_k127_7652811_1	583355.Caka_3039	8.951e-14	78.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7652811_0	518766.Rmar_0474	9.18e-106	354.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
DTH1_k127_7652811_2	1396141.BATP01000034_gene4198	3.662e-12	76.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
DTH1_k127_7656906_0	497964.CfE428DRAFT_5662	1.878e-219	700.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DTH1_k127_7658669_11	1210884.HG799475_gene15301	5.681e-07	59.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_7658669_9	497964.CfE428DRAFT_6148	4.236e-28	115.0	2DTD6@1|root,33JTS@2|Bacteria,46WA4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
DTH1_k127_7658669_10	1396418.BATQ01000166_gene1838	2.879e-22	98.0	2FCWX@1|root,344ZT@2|Bacteria,46WDE@74201|Verrucomicrobia,2IUVW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
DTH1_k127_7658669_5	497964.CfE428DRAFT_1451	4.312e-136	446.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DTH1_k127_7658669_0	497964.CfE428DRAFT_1455	5.767e-217	687.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
DTH1_k127_7658669_3	452637.Oter_3084	1.454e-141	458.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	414999|Opitutae	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH1_k127_7658669_1	497964.CfE428DRAFT_1457	1.677e-198	633.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	General secretory system II protein E domain protein	pulE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DTH1_k127_7658669_2	344747.PM8797T_29708	5.036e-180	573.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
DTH1_k127_7658669_6	481448.Minf_0287	3.903e-112	372.0	COG0191@1|root,COG0191@2|Bacteria,46TAJ@74201|Verrucomicrobia,37GA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
DTH1_k127_7658669_7	649349.Lbys_0013	4.768e-106	352.0	COG3718@1|root,COG3718@2|Bacteria,4NKW4@976|Bacteroidetes,47TKD@768503|Cytophagia	976|Bacteroidetes	G	KduI/IolB family	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
DTH1_k127_7658669_4	485913.Krac_4319	2.724e-141	456.0	COG0524@1|root,COG0524@2|Bacteria,2G5XM@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DTH1_k127_7658669_8	926550.CLDAP_26240	5.585e-103	347.0	COG3962@1|root,COG3962@2|Bacteria,2G68S@200795|Chloroflexi	200795|Chloroflexi	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH1_k127_7658824_2	1159870.KB907784_gene1774	8.369e-08	57.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2VJSF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
DTH1_k127_7658824_0	768671.ThimaDRAFT_0859	0.0	1090.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1WWMT@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_7658824_1	1163408.UU9_09042	9.907e-48	173.0	COG5380@1|root,COG5380@2|Bacteria,1QG74@1224|Proteobacteria	1224|Proteobacteria	O	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
DTH1_k127_7658824_3	762376.AXYL_01385	1.815e-05	49.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2VJSF@28216|Betaproteobacteria,3T6Z5@506|Alcaligenaceae	28216|Betaproteobacteria	P	C-terminal region of aryl-sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
DTH1_k127_7659257_2	1095743.HMPREF1054_0309	2.833e-21	101.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y8T2@135625|Pasteurellales	135625|Pasteurellales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
DTH1_k127_7659257_0	452637.Oter_2821	5.632e-173	571.0	COG0755@1|root,COG0755@2|Bacteria,46SIH@74201|Verrucomicrobia,3K7UF@414999|Opitutae	414999|Opitutae	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DTH1_k127_7659257_1	452637.Oter_2587	9.118e-54	193.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
DTH1_k127_7667809_5	1122917.KB899659_gene5085	5.33e-10	64.0	2E9V0@1|root,3340V@2|Bacteria,1VBMU@1239|Firmicutes,4IRRQ@91061|Bacilli,26ZN3@186822|Paenibacillaceae	91061|Bacilli	I	carotenoid biosynthetic process	-	-	-	ko:K10212	ko00906,map00906	-	R07656	RC00041	ko00000,ko00001,ko01000	-	-	-	-
DTH1_k127_7667809_1	1396141.BATP01000003_gene5044	8.405e-95	321.0	COG1215@1|root,COG1215@2|Bacteria,46WX3@74201|Verrucomicrobia,2IVN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH1_k127_7667809_3	682795.AciX8_1298	2.367e-17	85.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DTH1_k127_7667809_2	240016.ABIZ01000001_gene1135	7.852e-41	155.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia,2IVXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH1_k127_7667809_4	1158292.JPOE01000002_gene3555	8.326e-11	66.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH1_k127_7667809_0	1396141.BATP01000003_gene5043	1.038e-136	439.0	COG1233@1|root,COG1233@2|Bacteria,46SE8@74201|Verrucomicrobia,2IVA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
DTH1_k127_7671704_3	1218084.BBJK01000086_gene5778	1.375e-06	61.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
DTH1_k127_7671704_2	927658.AJUM01000034_gene376	1.298e-49	194.0	COG2133@1|root,COG2312@1|root,COG5563@1|root,COG2133@2|Bacteria,COG2312@2|Bacteria,COG5563@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc,LTD
DTH1_k127_7671704_1	240016.ABIZ01000001_gene5895	1.352e-130	420.0	COG2133@1|root,COG2133@2|Bacteria,46ZKI@74201|Verrucomicrobia,2IVI9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH1_k127_7671704_0	521674.Plim_3206	1.015e-198	632.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
DTH1_k127_76862_1	1396141.BATP01000003_gene4967	3.389e-98	337.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
DTH1_k127_76862_0	497964.CfE428DRAFT_1577	1.542e-157	505.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
DTH1_k127_76862_2	395493.BegalDRAFT_2935	7.043e-79	273.0	COG1408@1|root,COG1408@2|Bacteria,1RK37@1224|Proteobacteria,1SEEW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase activity	yaeI	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DTH1_k127_7698636_1	497964.CfE428DRAFT_2266	1.395e-199	630.0	COG0477@1|root,COG2814@2|Bacteria,46U08@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
DTH1_k127_7698636_2	497964.CfE428DRAFT_0193	7.035e-111	364.0	COG1210@1|root,COG1210@2|Bacteria,46S5P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH1_k127_7698636_0	497964.CfE428DRAFT_0194	1.905e-251	785.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
DTH1_k127_7706583_1	1123070.KB899251_gene716	6.585e-132	430.0	COG0045@1|root,COG0045@2|Bacteria,46TDG@74201|Verrucomicrobia,2ITNQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DTH1_k127_7706583_2	313624.NSP_27450	2.674e-53	207.0	COG1075@1|root,COG1075@2|Bacteria,1GIQY@1117|Cyanobacteria,1HP99@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7706583_0	448385.sce4763	3.919e-217	691.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DTH1_k127_7706583_4	228405.HNE_2756	1.277e-06	57.0	COG0322@1|root,COG0322@2|Bacteria,1PVWI@1224|Proteobacteria,2V74B@28211|Alphaproteobacteria,4402D@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	COG0322 Nuclease subunit of the excinuclease complex	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
DTH1_k127_7710038_0	314230.DSM3645_28167	1.525e-110	373.0	COG3039@1|root,COG3039@2|Bacteria,2J1M4@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
DTH1_k127_7710038_2	56780.SYN_02999	8.409e-21	93.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MRJM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH1_k127_7710038_3	251229.Chro_2352	8.449e-21	103.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721,ko:K07011,ko:K20444	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
DTH1_k127_7710038_1	357808.RoseRS_2382	2.302e-24	113.0	COG1216@1|root,COG1216@2|Bacteria,2GB2A@200795|Chloroflexi,377SM@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH1_k127_7722088_4	497964.CfE428DRAFT_6195	9.065e-80	270.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_7722088_0	33876.JNXY01000025_gene5296	9.19e-197	623.0	COG4225@1|root,COG4225@2|Bacteria,2I2TJ@201174|Actinobacteria,4DGGH@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
DTH1_k127_7722088_3	794903.OPIT5_16130	7.436e-93	314.0	COG1028@1|root,COG1028@2|Bacteria,46TD2@74201|Verrucomicrobia,3K7W5@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH1_k127_7722088_2	696369.KI912183_gene1481	5.938e-104	349.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH1_k127_7722088_7	452637.Oter_4555	5.086e-55	198.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7722088_6	469383.Cwoe_4579	8.609e-61	220.0	COG1994@1|root,COG1994@2|Bacteria,2H6BD@201174|Actinobacteria,4CS7E@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7722088_5	497964.CfE428DRAFT_4990	2.386e-67	250.0	COG3071@1|root,COG3071@2|Bacteria,46VFP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7722088_8	118173.KB235914_gene3105	2.985e-38	154.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
DTH1_k127_7722088_1	234267.Acid_7728	1.846e-171	548.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
DTH1_k127_7725685_5	518766.Rmar_2227	6.5e-07	51.0	COG2197@1|root,COG2197@2|Bacteria,4NP2G@976|Bacteroidetes,1FIR1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_7725685_4	1396141.BATP01000023_gene664	1.02e-10	73.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
DTH1_k127_7725685_3	1042375.AFPL01000055_gene2315	2.289e-61	222.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,467K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
DTH1_k127_7725685_0	1131269.AQVV01000050_gene421	2.432e-181	580.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DTH1_k127_7725685_1	1156937.MFUM_230019	1.592e-158	530.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,37GCF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
DTH1_k127_7725685_2	247490.KSU1_C0714	2.013e-131	454.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH1_k127_7728174_0	661478.OP10G_3858	2.864e-119	391.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yrbE	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_7728174_1	497964.CfE428DRAFT_3531	1.452e-114	380.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
DTH1_k127_7728174_2	497964.CfE428DRAFT_0769	1.163e-108	370.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_7728174_3	1499967.BAYZ01000159_gene538	1.355e-69	251.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_7728174_4	314230.DSM3645_26039	2.424e-42	171.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
DTH1_k127_7731214_0	452637.Oter_1295	1.034e-172	555.0	COG1012@1|root,COG1012@2|Bacteria,46UYV@74201|Verrucomicrobia,3K7HF@414999|Opitutae	414999|Opitutae	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
DTH1_k127_7731214_5	1403819.BATR01000059_gene1822	2.922e-55	196.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
DTH1_k127_7731214_7	278957.ABEA03000086_gene2506	8.742e-37	141.0	COG4576@1|root,COG4576@2|Bacteria,46VMK@74201|Verrucomicrobia,3K8BF@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
DTH1_k127_7731214_10	794903.OPIT5_04210	5.565e-31	125.0	COG4577@1|root,COG4577@2|Bacteria,46W1J@74201|Verrucomicrobia,3K8AE@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
DTH1_k127_7731214_1	794903.OPIT5_04205	1.611e-149	485.0	COG0282@1|root,COG0282@2|Bacteria,46TZF@74201|Verrucomicrobia,3K7U1@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
DTH1_k127_7731214_8	452637.Oter_1291	2.565e-35	137.0	COG4577@1|root,COG4577@2|Bacteria,46WBA@74201|Verrucomicrobia,3K89K@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
DTH1_k127_7731214_9	794903.OPIT5_04195	2.659e-33	130.0	COG4577@1|root,COG4577@2|Bacteria,46W7U@74201|Verrucomicrobia,3K8C2@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
DTH1_k127_7731214_3	278957.ABEA03000087_gene601	2.807e-101	343.0	COG4869@1|root,COG4869@2|Bacteria,46UMP@74201|Verrucomicrobia,3K7FS@414999|Opitutae	414999|Opitutae	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
DTH1_k127_7731214_6	314230.DSM3645_04975	5.865e-50	188.0	COG1349@1|root,COG1349@2|Bacteria,2IYW0@203682|Planctomycetes	203682|Planctomycetes	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
DTH1_k127_7731214_2	886293.Sinac_2714	2.3e-136	450.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_7731214_4	240016.ABIZ01000001_gene272	2.618e-62	226.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
DTH1_k127_7731214_11	794903.OPIT5_29490	4.83e-16	86.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_773629_1	497964.CfE428DRAFT_1492	2.822e-40	149.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH1_k127_773629_0	497964.CfE428DRAFT_2099	9.992e-202	647.0	COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH1_k127_77366_2	305700.B447_10758	0.0004922	51.0	2DU19@1|root,33NHC@2|Bacteria,1NKNM@1224|Proteobacteria,2VYQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_77366_0	211165.AJLN01000061_gene3942	1.036e-220	702.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,1JHUA@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
DTH1_k127_77366_1	1403819.BATR01000054_gene1700	1.246e-72	249.0	COG0431@1|root,COG0431@2|Bacteria,46SXE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH1_k127_7746310_1	344747.PM8797T_06060	2.116e-130	432.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_7746310_6	1385935.N836_03200	1.271e-11	76.0	COG2207@1|root,COG2207@2|Bacteria,1GBJH@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Response_reg
DTH1_k127_7746310_5	661478.OP10G_4770	1.383e-14	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_7746310_2	525904.Tter_1997	4.311e-125	409.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_7746310_0	1123508.JH636448_gene7659	5.93e-232	726.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
DTH1_k127_7746310_3	344747.PM8797T_05400	1.065e-53	201.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_7746310_4	344747.PM8797T_05400	1.064e-21	96.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_7758892_3	247490.KSU1_C1712	2.47e-23	115.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7758892_0	1267535.KB906767_gene4768	1.288e-131	442.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7758892_1	1198452.Jab_2c25040	5.854e-128	420.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2VPXR@28216|Betaproteobacteria,474PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	xynB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
DTH1_k127_7758892_2	118173.KB235914_gene3829	3.76e-121	407.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7764476_1	344747.PM8797T_31653	9.922e-58	217.0	2F8GG@1|root,340VA@2|Bacteria,2J3K0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7764476_2	504472.Slin_2680	2.311e-36	150.0	COG2133@1|root,COG3291@1|root,COG4625@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
DTH1_k127_7764476_0	344747.PM8797T_32040	1.386e-216	710.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
DTH1_k127_7764476_3	345341.KUTG_02670	3.904e-07	61.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4E6DX@85010|Pseudonocardiales	201174|Actinobacteria	O	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
DTH1_k127_7777173_7	6183.Smp_085540.6	0.0001398	55.0	COG5022@1|root,KOG0161@2759|Eukaryota,38CVC@33154|Opisthokonta,3BBPR@33208|Metazoa,3CSM1@33213|Bilateria	33208|Metazoa	Z	motor activity	unc-54	GO:0000003,GO:0000146,GO:0001667,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003008,GO:0003012,GO:0003674,GO:0003774,GO:0003779,GO:0003824,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005700,GO:0005703,GO:0005737,GO:0005856,GO:0005859,GO:0005863,GO:0006928,GO:0006936,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007517,GO:0007525,GO:0007527,GO:0007610,GO:0007626,GO:0007631,GO:0008092,GO:0008150,GO:0008307,GO:0009653,GO:0009888,GO:0009987,GO:0010631,GO:0010927,GO:0014866,GO:0015629,GO:0016043,GO:0016459,GO:0016460,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018991,GO:0019098,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030241,GO:0030707,GO:0030855,GO:0030898,GO:0031032,GO:0031033,GO:0031034,GO:0031647,GO:0031672,GO:0032501,GO:0032502,GO:0032504,GO:0032956,GO:0032970,GO:0032982,GO:0032989,GO:0032991,GO:0033043,GO:0034622,GO:0035556,GO:0036379,GO:0040011,GO:0042623,GO:0042692,GO:0042755,GO:0042802,GO:0042803,GO:0043050,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043292,GO:0043519,GO:0043520,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044427,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044703,GO:0044877,GO:0045214,GO:0046983,GO:0048017,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048609,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051015,GO:0051128,GO:0051146,GO:0051179,GO:0051239,GO:0051240,GO:0051493,GO:0051674,GO:0051704,GO:0051716,GO:0055001,GO:0055002,GO:0060278,GO:0060279,GO:0060361,GO:0060429,GO:0061061,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071688,GO:0071689,GO:0071840,GO:0090130,GO:0090132,GO:0097435,GO:0098687,GO:0099080,GO:0099081,GO:0099512,GO:2000241,GO:2000243	-	ko:K10352,ko:K17751	ko04260,ko04261,ko04530,ko05416,map04260,map04261,map04530,map05416	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	IQ,Myosin_N,Myosin_head,Myosin_tail_1
DTH1_k127_7777173_4	1410620.SHLA_36c000140	4.438e-61	222.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_7777173_2	1267535.KB906767_gene368	1.936e-83	291.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_7777173_0	518766.Rmar_1439	2.14e-235	748.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1439|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7777173_1	518766.Rmar_1438	1.015e-134	461.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1438|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7777173_5	1541065.JRFE01000058_gene5541	5.331e-22	104.0	2DBIE@1|root,32ZYG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7777173_6	1121406.JAEX01000009_gene2643	4.918e-06	59.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42QZ1@68525|delta/epsilon subdivisions,2WKYF@28221|Deltaproteobacteria,2MA59@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
DTH1_k127_7777173_3	335543.Sfum_1620	2.001e-76	271.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
DTH1_k127_7778281_1	246194.CHY_0260	9.833e-13	80.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto,Paired_CXXCH_1
DTH1_k127_7778281_2	1396141.BATP01000019_gene1718	2.351e-12	78.0	COG3225@1|root,COG3225@2|Bacteria,46UZA@74201|Verrucomicrobia,2IUBV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
DTH1_k127_7778281_0	756272.Plabr_0818	7.59e-212	670.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
DTH1_k127_7778281_3	1499967.BAYZ01000068_gene1988	0.0002093	49.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_7784769_0	497964.CfE428DRAFT_3691	5.76e-51	188.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH1_k127_7784769_1	1042156.CXIVA_02020	8.212e-25	109.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,36IUF@31979|Clostridiaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DTH1_k127_7784769_2	1034345.CAEM01000007_gene1354	1.254e-16	89.0	COG0454@1|root,COG0533@1|root,COG0456@2|Bacteria,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CUKY@84998|Coriobacteriia	84998|Coriobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
DTH1_k127_7861325_1	1396141.BATP01000030_gene3546	2.071e-172	559.0	COG4654@1|root,COG4654@2|Bacteria,46U75@74201|Verrucomicrobia,2IVE5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
DTH1_k127_7861325_0	1210884.HG799462_gene7951	6.877e-233	728.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_7861325_2	1123267.JONN01000001_gene1815	2.154e-11	70.0	COG1426@1|root,COG1426@2|Bacteria,1ND8D@1224|Proteobacteria,2UB49@28211|Alphaproteobacteria,2K57P@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
DTH1_k127_7881791_1	1123277.KB893244_gene5166	2.474e-40	156.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH1_k127_7881791_0	530564.Psta_3476	2.15e-97	338.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,NPCBM
DTH1_k127_78893_2	234267.Acid_2129	7.213e-68	241.0	COG0693@1|root,COG0693@2|Bacteria,3Y3JB@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
DTH1_k127_78893_1	1123399.AQVE01000001_gene684	8.175e-106	381.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
DTH1_k127_78893_4	497964.CfE428DRAFT_5098	2.824e-29	137.0	COG1075@1|root,COG1404@1|root,COG3055@1|root,COG3391@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.1.3.6,3.2.1.4	ko:K01179,ko:K03333,ko:K12287	ko00500,ko00984,ko01100,ko01120,map00500,map00984,map01100,map01120	-	R01459,R06200,R11307,R11308	RC00146	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin
DTH1_k127_78893_6	497964.CfE428DRAFT_4431	1.517e-11	79.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
DTH1_k127_78893_7	246194.CHY_0024	2.089e-11	68.0	COG0432@1|root,COG0432@2|Bacteria,1V201@1239|Firmicutes,24FTY@186801|Clostridia,42G53@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH1_k127_78893_9	1123073.KB899242_gene1643	2.501e-05	57.0	COG1520@1|root,COG5571@1|root,COG1520@2|Bacteria,COG5571@2|Bacteria	2|Bacteria	N	outer membrane autotransporter	yhjY	-	-	ko:K12287,ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,DUF4421,Lipase_GDSL
DTH1_k127_78893_5	760192.Halhy_1640	2.026e-25	112.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1IQJB@117747|Sphingobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
DTH1_k127_78893_3	382464.ABSI01000011_gene2968	7.793e-53	210.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_78893_8	1189620.AJXL01000074_gene3244	3.324e-09	68.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia,2NSYB@237|Flavobacterium	976|Bacteroidetes	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_78893_0	1396141.BATP01000060_gene4727	1.384e-221	732.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
DTH1_k127_78893_10	268407.PWYN_09035	0.000334	50.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,26U3R@186822|Paenibacillaceae	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
DTH1_k127_7893209_3	1142394.PSMK_15610	4.099e-31	136.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH1_k127_7893209_2	1487923.DP73_10970	1.05e-33	141.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
DTH1_k127_7893209_4	1125863.JAFN01000001_gene727	1.726e-27	125.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
DTH1_k127_7893209_0	313628.LNTAR_12671	1.586e-184	598.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
DTH1_k127_7893209_1	313628.LNTAR_12676	8.602e-62	217.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_7893355_2	452637.Oter_0751	6.45e-211	661.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH1_k127_7893355_5	1121413.JMKT01000008_gene1370	5.199e-24	114.0	2BR4E@1|root,32K2C@2|Bacteria,1Q2KP@1224|Proteobacteria,42X9C@68525|delta/epsilon subdivisions,2WSUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7893355_0	452637.Oter_0753	1.92e-282	879.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	2|Bacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ndhD5	-	1.6.5.3	ko:K05568,ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2	-	iJN678.ndhD	Proton_antipo_M
DTH1_k127_7893355_1	452637.Oter_0754	2.21e-215	681.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,3K7XF@414999|Opitutae	414999|Opitutae	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH1_k127_7893355_3	452637.Oter_0755	1.926e-178	571.0	COG1007@1|root,COG1007@2|Bacteria,46W5N@74201|Verrucomicrobia,3K8V4@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH1_k127_7893355_4	1267534.KB906754_gene3777	3.974e-85	286.0	COG1143@1|root,COG1143@2|Bacteria,3Y6N6@57723|Acidobacteria,2JKQS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
DTH1_k127_7909215_7	1463861.JNXE01000016_gene7405	1.21e-10	64.0	COG5520@1|root,COG5520@2|Bacteria,2GMWN@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C,Ricin_B_lectin
DTH1_k127_7909215_1	1267535.KB906767_gene4130	9.154e-90	310.0	COG2133@1|root,COG2133@2|Bacteria,3Y6W0@57723|Acidobacteria	57723|Acidobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH1_k127_7909215_4	243090.RB2897	3.859e-36	145.0	COG3963@1|root,COG3963@2|Bacteria,2IZWV@203682|Planctomycetes	203682|Planctomycetes	I	Methyltransferase domain	-	-	2.1.1.344	ko:K22309	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
DTH1_k127_7909215_0	497964.CfE428DRAFT_3485	1.61e-175	558.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_7909215_3	459349.CLOAM0160	6.041e-41	164.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
DTH1_k127_7909215_6	755178.Cyan10605_0953	9.815e-11	74.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria	1117|Cyanobacteria	M	bicarbonate transporter, IctB family	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
DTH1_k127_7909215_5	338966.Ppro_1664	4.037e-32	138.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,43BTG@68525|delta/epsilon subdivisions,2X74B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
DTH1_k127_7909215_2	489825.LYNGBM3L_17040	5.999e-50	188.0	COG1266@1|root,COG1266@2|Bacteria,1G5HB@1117|Cyanobacteria,1HAXC@1150|Oscillatoriales	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DTH1_k127_7929536_5	1121918.ARWE01000001_gene1207	1.525e-08	60.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,43UIE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
DTH1_k127_7929536_4	1189620.AJXL01000002_gene1866	5.013e-19	95.0	COG2032@1|root,COG2032@2|Bacteria,4NGGW@976|Bacteroidetes,1HY8P@117743|Flavobacteriia,2NYDV@237|Flavobacterium	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
DTH1_k127_7929536_6	1089545.KB913037_gene8972	1.017e-06	58.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
DTH1_k127_7929536_2	886293.Sinac_3371	6.106e-29	135.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_7929536_0	452637.Oter_2583	4.917e-82	281.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH1_k127_7929536_1	452637.Oter_0299	1.663e-45	170.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_7929536_3	452637.Oter_0300	1.124e-22	108.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF3379
DTH1_k127_7929536_7	278957.ABEA03000106_gene1817	1.427e-06	59.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7931239_0	697284.ERIC2_c41250	1.455e-125	419.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,26RSI@186822|Paenibacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
DTH1_k127_7948188_1	1121920.AUAU01000004_gene839	5.488e-62	216.0	COG0590@1|root,COG0590@2|Bacteria,3Y4ZN@57723|Acidobacteria	57723|Acidobacteria	FJ	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
DTH1_k127_7948188_2	1125701.HMPREF1221_01616	1.509e-48	192.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_7948188_0	1242864.D187_003088	3.241e-114	382.0	COG2931@1|root,COG3055@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
DTH1_k127_7954298_0	794903.OPIT5_28885	2.272e-113	381.0	COG0489@1|root,COG0489@2|Bacteria,46SAV@74201|Verrucomicrobia,3K75Q@414999|Opitutae	414999|Opitutae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DTH1_k127_7954298_1	324057.Pjdr2_0886	5.183e-50	194.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
DTH1_k127_7954298_2	251221.35212624	8.908e-50	178.0	COG3961@1|root,COG3961@2|Bacteria,1G1A5@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the TPP enzyme family	pdc	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH1_k127_7985903_1	1120950.KB892744_gene2755	4.678e-45	189.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_6,DLH,Peptidase_S9
DTH1_k127_7985903_0	1120950.KB892756_gene6635	4.407e-90	332.0	29XIB@1|root,30J98@2|Bacteria,2H3UJ@201174|Actinobacteria	201174|Actinobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
DTH1_k127_7989845_1	1210884.HG799468_gene13605	3.06e-151	497.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
DTH1_k127_7989845_0	497964.CfE428DRAFT_5300	1.29e-159	513.0	COG0673@1|root,COG0673@2|Bacteria,46S8U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_7991286_2	1121015.N789_07310	7.037e-11	64.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RRY3@1236|Gammaproteobacteria,1XBYN@135614|Xanthomonadales	135614|Xanthomonadales	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH1_k127_7991286_1	1122138.AQUZ01000027_gene785	1.846e-39	169.0	COG3408@1|root,COG3408@2|Bacteria,2GYU2@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl-hydrolase family 116, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DUF608
DTH1_k127_7991286_0	497964.CfE428DRAFT_3520	1.038e-70	246.0	COG2197@1|root,COG2197@2|Bacteria,46UHN@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_7999300_2	411479.BACUNI_04071	7.174e-75	269.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH1_k127_7999300_0	1121106.JQKB01000056_gene5861	0.0	1143.0	COG1413@1|root,COG1413@2|Bacteria,1R5Z1@1224|Proteobacteria	1224|Proteobacteria	C	lyase activity	capB	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	-
DTH1_k127_8005171_3	251221.35214536	6.328e-93	337.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1G4UJ@1117|Cyanobacteria	1117|Cyanobacteria	CO	Disulphide bond corrector protein DsbC	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH1_k127_8005171_1	1123508.JH636442_gene3931	1.206e-147	477.0	COG1506@1|root,COG1506@2|Bacteria,2IWTJ@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH1_k127_8005171_2	240016.ABIZ01000001_gene4409	5.583e-103	342.0	COG3828@1|root,COG3828@2|Bacteria,46SV1@74201|Verrucomicrobia,2IV8Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
DTH1_k127_8005171_0	448385.sce7733	1.176e-304	947.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
DTH1_k127_8013828_1	572477.Alvin_0517	2.7e-64	230.0	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,1RWJZ@1236|Gammaproteobacteria,1WXIW@135613|Chromatiales	135613|Chromatiales	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
DTH1_k127_8013828_0	742725.HMPREF9450_01532	1.65e-68	251.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,2FQGR@200643|Bacteroidia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH1_k127_8018059_0	452637.Oter_2551	2.383e-96	326.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH1_k127_8018059_2	706587.Desti_5389	8.152e-22	99.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DTH1_k127_8018059_1	575540.Isop_2574	1.639e-92	310.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
DTH1_k127_8041858_0	1298867.AUES01000066_gene4685	1.498e-57	231.0	COG1572@1|root,COG1572@2|Bacteria,1QVRG@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Calx-beta,DUF5122
DTH1_k127_8041858_1	1353537.TP2_00585	1.297e-39	172.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG4625@1|root,COG4935@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4625@2|Bacteria,COG4935@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,DUF4214,HemolysinCabind,Hint_2
DTH1_k127_8041858_3	1190603.AJYD01000067_gene3196	1.756e-05	47.0	2DS85@1|root,33EYM@2|Bacteria,1NJQN@1224|Proteobacteria,1SHH9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8052559_0	742725.HMPREF9450_01261	5.9e-135	446.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,4PAMG@976|Bacteroidetes,2FXAJ@200643|Bacteroidia	976|Bacteroidetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
DTH1_k127_8052559_3	1123070.KB899250_gene635	0.0006183	48.0	COG1918@1|root,COG1918@2|Bacteria,46ZGK@74201|Verrucomicrobia,2IWG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
DTH1_k127_8052559_1	1550073.JROH01000032_gene1995	1.897e-123	411.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,2K21U@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
DTH1_k127_8052559_2	700598.Niako_5718	4.757e-60	211.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1IQ8D@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
DTH1_k127_8061267_1	1382359.JIAL01000001_gene1578	1.765e-91	307.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH1_k127_8061267_0	649638.Trad_2886	9.482e-120	396.0	COG1057@1|root,COG1057@2|Bacteria	2|Bacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	CTP_transf_like
DTH1_k127_8064645_1	589865.DaAHT2_1111	4.899e-167	535.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DTH1_k127_8064645_0	589865.DaAHT2_1112	2.465e-256	806.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
DTH1_k127_8064645_4	344747.PM8797T_28884	2.165e-58	214.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH1_k127_8064645_3	452637.Oter_0906	4.253e-74	266.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH1_k127_8064645_2	1379698.RBG1_1C00001G0011	3.603e-106	361.0	COG2010@1|root,COG2180@1|root,COG2010@2|Bacteria,COG2180@2|Bacteria,2NR8D@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K00405,ko:K17052	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko02000	3.D.4.3,5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
DTH1_k127_8079269_1	1123392.AQWL01000002_gene1978	3.42e-166	540.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH1_k127_8079269_3	1238182.C882_0258	1.699e-58	222.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
DTH1_k127_8079269_4	530564.Psta_0781	1.923e-17	90.0	COG1309@1|root,COG1309@2|Bacteria,2J1M7@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH1_k127_8079269_0	468059.AUHA01000006_gene2919	1.484e-196	624.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH1_k127_8079269_2	278963.ATWD01000002_gene820	8.877e-90	302.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JKYS@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH1_k127_8082851_1	886293.Sinac_3711	2.206e-97	330.0	COG2896@1|root,COG2896@2|Bacteria,2IXWS@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
DTH1_k127_8082851_3	452637.Oter_2046	8.147e-29	124.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia,3K9NW@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
DTH1_k127_8082851_4	1265505.ATUG01000001_gene3561	1.709e-10	68.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
DTH1_k127_8082851_2	1476973.JMMB01000007_gene3240	2.722e-34	146.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
DTH1_k127_8082851_0	497964.CfE428DRAFT_5481	6.593e-164	531.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
DTH1_k127_8084008_1	518766.Rmar_2306	1.163e-88	299.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DTH1_k127_8084008_4	1411123.JQNH01000001_gene19	5.086e-18	87.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DTH1_k127_8084008_2	857087.Metme_4292	1.477e-75	268.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1XH04@135618|Methylococcales	1236|Gammaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
DTH1_k127_8084008_0	452637.Oter_1491	6.735e-105	351.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH1_k127_8091263_3	1142394.PSMK_15660	7.07e-28	128.0	COG3147@1|root,COG3147@2|Bacteria,2IXFB@203682|Planctomycetes	203682|Planctomycetes	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8091263_2	867903.ThesuDRAFT_02283	2.717e-30	128.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WCD6@538999|Clostridiales incertae sedis	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH1_k127_8091263_0	156889.Mmc1_2003	1.339e-130	430.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
DTH1_k127_8091263_4	395494.Galf_1566	2.18e-15	78.0	COG0790@1|root,COG3087@1|root,COG0790@2|Bacteria,COG3087@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
DTH1_k127_8091263_1	497964.CfE428DRAFT_6151	8.573e-66	233.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH1_k127_809860_2	382464.ABSI01000007_gene4191	2.907e-102	351.0	COG2833@1|root,COG2833@2|Bacteria,46YYE@74201|Verrucomicrobia,2ITUP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
DTH1_k127_809860_1	497964.CfE428DRAFT_2502	5.689e-187	605.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DTH1_k127_809860_0	497964.CfE428DRAFT_1254	0.0	1156.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
DTH1_k127_8131007_0	1267535.KB906767_gene1553	1.838e-164	539.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
DTH1_k127_8131007_1	344747.PM8797T_03419	1.322e-58	214.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH1_k127_8131007_2	1385935.N836_16125	1.204e-47	178.0	COG5434@1|root,COG5434@2|Bacteria,1GC14@1117|Cyanobacteria,1HF7U@1150|Oscillatoriales	1117|Cyanobacteria	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
DTH1_k127_8133298_2	452637.Oter_2237	7.663e-83	278.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH1_k127_8133298_5	452637.Oter_2236	6.586e-12	66.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
DTH1_k127_8133298_1	526224.Bmur_0878	1.257e-114	378.0	COG0616@1|root,COG0616@2|Bacteria,2J9E9@203691|Spirochaetes	203691|Spirochaetes	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
DTH1_k127_8133298_3	452637.Oter_0107	4.261e-61	222.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	frnE	-	-	-	-	-	-	-	-	-	-	-	DSBA
DTH1_k127_8133298_0	497964.CfE428DRAFT_6515	5.567e-295	968.0	COG0457@1|root,COG0457@2|Bacteria,46UKC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	FAT,Peptidase_C39_2
DTH1_k127_8133298_4	497964.CfE428DRAFT_2396	4.209e-32	133.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
DTH1_k127_8133298_6	497964.CfE428DRAFT_2396	8.804e-11	64.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
DTH1_k127_8146755_2	673860.AciM339_1573	6.164e-11	65.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
DTH1_k127_8146755_0	880072.Desac_1581	3.119e-202	642.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MR7G@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH1_k127_8146755_1	1382359.JIAL01000001_gene620	1.085e-45	170.0	COG0414@1|root,COG0414@2|Bacteria,3Y40A@57723|Acidobacteria,2JHS1@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
DTH1_k127_8216352_1	278957.ABEA03000086_gene2488	1.006e-31	142.0	COG3170@1|root,COG3170@2|Bacteria,46Y8C@74201|Verrucomicrobia,3K93X@414999|Opitutae	414999|Opitutae	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8216352_0	234267.Acid_2413	1.349e-59	215.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
DTH1_k127_8257877_0	1125863.JAFN01000001_gene1060	4.656e-97	338.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH1_k127_8257877_1	382464.ABSI01000011_gene2595	4.18e-52	203.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
DTH1_k127_8257877_2	1123278.KB893412_gene2915	7.504e-50	201.0	COG1874@1|root,COG2755@1|root,COG4447@1|root,COG1874@2|Bacteria,COG2755@2|Bacteria,COG4447@2|Bacteria,4NX71@976|Bacteroidetes,47W14@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8261053_0	497964.CfE428DRAFT_4284	7.242e-260	814.0	COG0674@1|root,COG0674@2|Bacteria,46SM9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH1_k127_8261053_1	497964.CfE428DRAFT_4282	3.629e-151	482.0	COG1013@1|root,COG1013@2|Bacteria,46SRY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH1_k127_8261053_3	269799.Gmet_2576	3.53e-31	129.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,42SDV@68525|delta/epsilon subdivisions,2WPXR@28221|Deltaproteobacteria,43T4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH1_k127_8261053_2	756272.Plabr_2090	4.564e-79	271.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
DTH1_k127_8261053_4	909663.KI867150_gene2927	1.055e-21	102.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MR1B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	acs	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
DTH1_k127_8291035_0	1097668.BYI23_C006580	8.976e-74	262.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
DTH1_k127_8291035_1	1229205.BUPH_01539	1.348e-70	259.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
DTH1_k127_8291035_3	497964.CfE428DRAFT_0064	1.743e-56	205.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
DTH1_k127_8291035_4	518766.Rmar_1172	4.137e-51	193.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,4PEVF@976|Bacteroidetes,1FJP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
DTH1_k127_8291035_5	1396418.BATQ01000001_gene1289	4.228e-34	142.0	COG1321@1|root,COG1321@2|Bacteria,46VZN@74201|Verrucomicrobia,2IUJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
DTH1_k127_8291035_6	452637.Oter_1500	5.536e-29	123.0	COG3824@1|root,COG3824@2|Bacteria,46WK7@74201|Verrucomicrobia,3K8CH@414999|Opitutae	414999|Opitutae	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
DTH1_k127_8291035_2	326427.Cagg_0204	6.939e-68	255.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
DTH1_k127_8309752_2	1268240.ATFI01000008_gene2321	8.7e-109	363.0	COG2271@1|root,COG2271@2|Bacteria,4NH5M@976|Bacteroidetes,2FNV1@200643|Bacteroidia,4AMZP@815|Bacteroidaceae	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
DTH1_k127_8309752_0	1499967.BAYZ01000182_gene4442	9.504e-119	390.0	COG0673@1|root,COG0673@2|Bacteria,2NQJN@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_8309752_1	926550.CLDAP_26140	3.88e-109	359.0	COG1082@1|root,COG1082@2|Bacteria,2G613@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH1_k127_8311500_9	757424.Hsero_3022	2.518e-05	55.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VIZN@28216|Betaproteobacteria,473DT@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	wspA	-	-	ko:K13487	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
DTH1_k127_8311500_5	452637.Oter_0434	7.092e-46	172.0	COG0835@1|root,COG0835@2|Bacteria,46VRE@74201|Verrucomicrobia,3K82Y@414999|Opitutae	414999|Opitutae	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
DTH1_k127_8311500_1	671143.DAMO_1541	2.285e-146	473.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
DTH1_k127_8311500_2	497964.CfE428DRAFT_2620	3.736e-116	379.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH1_k127_8311500_6	665571.STHERM_c16620	5.125e-25	121.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH1_k127_8311500_8	1499967.BAYZ01000073_gene2050	3.004e-08	65.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD,HAD_2,Hydrolase,Hydrolase_like
DTH1_k127_8311500_4	1347392.CCEZ01000010_gene2401	8.406e-47	181.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,36EZ7@31979|Clostridiaceae	186801|Clostridia	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DTH1_k127_8311500_0	926550.CLDAP_09870	1.8e-180	582.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
DTH1_k127_8311500_3	744872.Spica_2486	8.542e-94	319.0	COG0438@1|root,COG0438@2|Bacteria,2J6VH@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH1_k127_8314535_0	497964.CfE428DRAFT_2718	5.495e-51	184.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH1_k127_8314535_1	1288963.ADIS_0819	1.325e-42	159.0	COG1501@1|root,COG1501@2|Bacteria,4NH0T@976|Bacteroidetes,47TMI@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
DTH1_k127_8326826_1	211165.AJLN01000100_gene4246	2.293e-86	291.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
DTH1_k127_8326826_6	1173023.KE650771_gene983	0.0001803	47.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
DTH1_k127_8326826_0	266117.Rxyl_3138	5.033e-140	454.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH1_k127_8326826_3	143224.JQMD01000002_gene4173	2.88e-34	137.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,1I340@117743|Flavobacteriia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
DTH1_k127_8326826_2	497964.CfE428DRAFT_4056	4.844e-67	235.0	COG2755@1|root,COG2755@2|Bacteria,46T12@74201|Verrucomicrobia	74201|Verrucomicrobia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH1_k127_8326826_5	566466.NOR53_2254	8.73e-13	79.0	COG2304@1|root,COG2931@1|root,COG3209@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1J94H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MQ	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,He_PIG,HemolysinCabind,VWA_2
DTH1_k127_8326826_4	471870.BACINT_01447	1.301e-31	141.0	2C4R9@1|root,32RED@2|Bacteria,4P0US@976|Bacteroidetes,2FRJU@200643|Bacteroidia,4AP05@815|Bacteroidaceae	976|Bacteroidetes	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH1_k127_8352995_2	1313172.YM304_11360	6.722e-46	172.0	COG2081@1|root,COG2081@2|Bacteria,2H11G@201174|Actinobacteria	201174|Actinobacteria	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH1_k127_8352995_0	452637.Oter_1311	1.948e-76	264.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8352995_3	886293.Sinac_3510	1.264e-42	170.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,PKD
DTH1_k127_8352995_1	1379698.RBG1_1C00001G0608	2.661e-68	253.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
DTH1_k127_8352995_5	35754.JNYJ01000007_gene2850	0.0003484	53.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DAT5@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
DTH1_k127_8352995_4	479432.Sros_0936	5.226e-11	75.0	COG3188@1|root,COG3188@2|Bacteria,2HQZC@201174|Actinobacteria,4EFZ0@85012|Streptosporangiales	201174|Actinobacteria	NU	Glycosyl hydrolase family 48	cbhB	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_48
DTH1_k127_8366100_0	240016.ABIZ01000001_gene3005	1.139e-82	280.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH1_k127_8366100_3	1499967.BAYZ01000171_gene5607	1.14e-36	145.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH1_k127_8366100_6	1499967.BAYZ01000171_gene5607	2.273e-08	56.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH1_k127_8366100_5	794903.OPIT5_26490	3.779e-14	76.0	2C4M3@1|root,2ZD1R@2|Bacteria,46WTA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_2
DTH1_k127_8366100_4	1007103.AFHW01000034_gene2097	8.41e-25	107.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,26QK1@186822|Paenibacillaceae	91061|Bacilli	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH1_k127_8366100_2	111781.Lepto7376_0105	8.063e-41	163.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
DTH1_k127_8366100_1	1510531.JQJJ01000010_gene2312	3.66e-76	268.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
DTH1_k127_8385310_0	1304872.JAGC01000003_gene2354	2.778e-128	427.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
DTH1_k127_8385310_1	706587.Desti_0466	9.362e-21	101.0	COG0265@1|root,COG1262@1|root,COG0265@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria,2MRZF@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Peptidase_C14
DTH1_k127_8402958_2	616991.JPOO01000003_gene1322	9.346e-22	100.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,23G5Z@178469|Arenibacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
DTH1_k127_8402958_0	1267535.KB906767_gene1828	7.015e-283	890.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	iraD	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11897,ko:K21637	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
DTH1_k127_8402958_1	497964.CfE428DRAFT_6180	1.642e-82	279.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
DTH1_k127_8404888_1	1396141.BATP01000056_gene3278	8.672e-25	121.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
DTH1_k127_8404888_0	56780.SYN_01127	5.334e-32	144.0	COG1345@1|root,COG1957@1|root,COG3204@1|root,COG1345@2|Bacteria,COG1957@2|Bacteria,COG3204@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8410728_3	7739.XP_002590144.1	2.678e-09	61.0	COG4287@1|root,2QU2G@2759|Eukaryota,38HH5@33154|Opisthokonta,3BGHK@33208|Metazoa,3D4EH@33213|Bilateria,48ENF@7711|Chordata	33208|Metazoa	S	PhoPQ-activated pathogenicity-related protein	-	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
DTH1_k127_8410728_1	1396418.BATQ01000058_gene90	1.075e-123	400.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DTH1_k127_8410728_2	1303518.CCALI_02658	2.614e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_8410728_0	1303518.CCALI_00581	7.658e-142	468.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	ywjF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Nitrate_red_gam
DTH1_k127_8413025_1	497964.CfE428DRAFT_5188	1.217e-95	319.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DTH1_k127_8413025_3	481448.Minf_2177	1.437e-34	135.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DTH1_k127_8413025_0	452637.Oter_2054	6.108e-272	844.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH1_k127_8413025_2	497964.CfE428DRAFT_1374	4.143e-59	223.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
DTH1_k127_8438667_1	1094980.Mpsy_1661	1.772e-25	114.0	arCOG03571@1|root,arCOG06820@1|root,arCOG03571@2157|Archaea,arCOG06820@2157|Archaea,2XVYD@28890|Euryarchaeota,2N917@224756|Methanomicrobia	224756|Methanomicrobia	S	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	YoaP
DTH1_k127_8438667_0	383372.Rcas_0560	1.111e-132	446.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
DTH1_k127_8455517_2	696281.Desru_0933	8.963e-41	156.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DTH1_k127_8455517_3	493475.GARC_3222	6.252e-31	135.0	COG0652@1|root,COG0652@2|Bacteria,1RCXX@1224|Proteobacteria,1S3ZN@1236|Gammaproteobacteria,466T7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DTH1_k127_8455517_0	497964.CfE428DRAFT_4164	1.474e-66	237.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DTH1_k127_8455517_1	1459636.NTE_02269	4.69e-50	184.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
DTH1_k127_8456632_0	452637.Oter_2235	6.38e-129	419.0	COG0460@1|root,COG0460@2|Bacteria,46TFC@74201|Verrucomicrobia,3K7MC@414999|Opitutae	414999|Opitutae	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
DTH1_k127_8456632_2	1396418.BATQ01000185_gene2133	2.54e-07	63.0	COG3203@1|root,COG3420@1|root,COG4782@1|root,COG5184@1|root,COG3203@2|Bacteria,COG3420@2|Bacteria,COG4782@2|Bacteria,COG5184@2|Bacteria,46TZK@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,Pectinesterase
DTH1_k127_8456632_1	1191523.MROS_2048	1.579e-66	247.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
DTH1_k127_8496598_8	243090.RB683	4.403e-17	81.0	COG1012@1|root,COG1012@2|Bacteria,2J2QD@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH1_k127_8496598_0	234267.Acid_4168	3.953e-195	619.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH1_k127_8496598_1	234267.Acid_4169	8.221e-163	524.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH1_k127_8496598_5	177439.DP2557	8.509e-35	145.0	2EVII@1|root,33NYR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8496598_3	177439.DP2558	8.955e-81	301.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K07459,ko:K10110	ko02010,map02010	M00194,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22,3.A.1.2	-	-	AAA_11,AAA_12,AAA_13,AAA_23
DTH1_k127_8496598_6	205918.Psyr_0855	9.424e-21	105.0	28IQ1@1|root,2Z8PV@2|Bacteria,1NYS1@1224|Proteobacteria,1RPR2@1236|Gammaproteobacteria,1Z57B@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	-	-	IV02_13120	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8496598_7	686340.Metal_0410	2.378e-20	96.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1XGTV@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
DTH1_k127_8496598_2	1183438.GKIL_2517	1.391e-129	429.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH1_k127_8496598_4	234267.Acid_6481	9.994e-66	227.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_8499751_0	926550.CLDAP_04870	3.114e-123	418.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH1_k127_8499751_2	1123242.JH636434_gene3261	0.0006341	44.0	2E02K@1|root,32KJE@2|Bacteria,2J430@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8499751_1	768710.DesyoDRAFT_1525	3.837e-59	221.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,2644X@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
DTH1_k127_8526299_2	443143.GM18_4055	1.607e-61	226.0	COG0304@1|root,COG0304@2|Bacteria,1RAFK@1224|Proteobacteria,42R69@68525|delta/epsilon subdivisions,2WMWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH1_k127_8526299_6	555779.Dthio_PD0800	1.263e-08	64.0	COG0304@1|root,COG0304@2|Bacteria,1R0WN@1224|Proteobacteria,43D2H@68525|delta/epsilon subdivisions,2X89P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ketoacyl-synt
DTH1_k127_8526299_4	1121918.ARWE01000001_gene3128	8.476e-24	105.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WQ0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH1_k127_8526299_0	575615.HMPREF0670_01520	7.467e-86	312.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,2FPUI@200643|Bacteroidia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_2,Ketoacyl-synt_C,ketoacyl-synt
DTH1_k127_8526299_3	1347393.HG726029_gene2088	1.466e-46	180.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,2FR15@200643|Bacteroidia,4AP6F@815|Bacteroidaceae	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
DTH1_k127_8526299_5	443143.GM18_4060	2.869e-14	81.0	COG2834@1|root,COG2834@2|Bacteria,1N3XP@1224|Proteobacteria,42TP4@68525|delta/epsilon subdivisions,2WQR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
DTH1_k127_8526299_7	1232437.KL661961_gene3016	2.863e-08	65.0	COG0764@1|root,COG0764@2|Bacteria,1NNU2@1224|Proteobacteria,437EX@68525|delta/epsilon subdivisions,2X2M8@28221|Deltaproteobacteria,2MP7V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
DTH1_k127_8526299_1	1313421.JHBV01000138_gene1213	8.309e-76	275.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,1J0M9@117747|Sphingobacteriia	976|Bacteroidetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
DTH1_k127_8537068_1	1396418.BATQ01000046_gene6113	3.367e-114	374.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,2ITSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	S4,tRNA-synt_1b
DTH1_k127_8537068_6	278957.ABEA03000069_gene3974	5.156e-05	53.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_8537068_2	452637.Oter_1562	3.514e-109	369.0	COG2271@1|root,COG2271@2|Bacteria,46W2G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Major Facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
DTH1_k127_8537068_4	1118054.CAGW01000014_gene225	4.437e-29	126.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,26XF4@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	adaB	-	2.1.1.63	ko:K00567,ko:K10778,ko:K13531	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DTH1_k127_8537068_5	481448.Minf_2165	9.117e-12	74.0	2FHDV@1|root,34981@2|Bacteria,46W9B@74201|Verrucomicrobia,37GRP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8537068_0	652103.Rpdx1_1424	1.339e-132	430.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,3JRQ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46,4.2.1.76,5.1.3.2	ko:K01710,ko:K01784,ko:K12450	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00293,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH1_k127_8537068_3	1121033.AUCF01000009_gene1195	2.683e-48	179.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria,2JRKZ@204441|Rhodospirillales	204441|Rhodospirillales	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH1_k127_8542787_1	1173027.Mic7113_2682	8.588e-25	111.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
DTH1_k127_8542787_2	314345.SPV1_00987	7.819e-08	61.0	2DPGY@1|root,3320R@2|Bacteria,1ND7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
DTH1_k127_8542787_0	1123393.KB891317_gene2207	3.745e-104	346.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VQ9J@28216|Betaproteobacteria,1KSDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
DTH1_k127_8542787_3	452637.Oter_1161	7.509e-07	53.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
DTH1_k127_8546310_0	497964.CfE428DRAFT_5031	2.125e-197	627.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_8546310_1	1396418.BATQ01000147_gene3609	3.648e-180	582.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_8551154_0	583355.Caka_3109	3.775e-112	394.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
DTH1_k127_8560511_1	1123073.KB899241_gene2073	7.552e-81	282.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,1RRWB@1236|Gammaproteobacteria,1X353@135614|Xanthomonadales	135614|Xanthomonadales	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
DTH1_k127_8560511_3	158787.BSCA_0674	8.644e-05	55.0	COG5305@1|root,COG5305@2|Bacteria,2HZBN@201174|Actinobacteria,4CZKJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH1_k127_8560511_0	497964.CfE428DRAFT_2614	7.144e-104	346.0	COG4989@1|root,COG4989@2|Bacteria,46SU2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH1_k127_8560511_2	309801.trd_0093	2.362e-21	101.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,27YFE@189775|Thermomicrobia	189775|Thermomicrobia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DTH1_k127_8561638_1	861299.J421_1753	2.338e-177	581.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH1_k127_8561638_0	1121346.KB899817_gene3149	1.367e-295	921.0	COG0129@1|root,COG0129@2|Bacteria,1U56J@1239|Firmicutes,4HD31@91061|Bacilli,26U7U@186822|Paenibacillaceae	91061|Bacilli	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
DTH1_k127_8568409_0	273068.TTE0217	4.473e-102	345.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia,42HVC@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
DTH1_k127_8568409_1	402777.KB235904_gene3701	0.0001961	51.0	2E1K5@1|root,32WXN@2|Bacteria,1G8HZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Immunity protein Imm1	-	-	-	-	-	-	-	-	-	-	-	-	Imm1
DTH1_k127_8597938_2	344747.PM8797T_13600	4.808e-11	72.0	COG2165@1|root,COG2165@2|Bacteria,2J223@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_8597938_3	794903.OPIT5_23755	0.0003797	46.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DTH1_k127_8597938_0	1396418.BATQ01000012_gene4420	1.716e-199	627.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH1_k127_8597938_1	1156937.MFUM_580004	5.776e-57	206.0	COG1060@1|root,COG1060@2|Bacteria,46TD4@74201|Verrucomicrobia,37FWU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DTH1_k127_8601405_0	794903.OPIT5_17320	2.865e-228	731.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CarboxypepD_reg,DUF11,NPCBM_assoc,Peptidase_M66
DTH1_k127_8627206_1	309799.DICTH_0054	2.497e-20	102.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	wrbA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_1,Flavodoxin_5,YjgF_endoribonc
DTH1_k127_8627206_0	1125701.HMPREF1221_01616	1.876e-47	190.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8627206_2	32057.KB217483_gene9816	0.0001477	46.0	COG1861@1|root,COG1861@2|Bacteria,1G3T7@1117|Cyanobacteria,1HS9T@1161|Nostocales	1117|Cyanobacteria	M	SPTR Transposase IS1380 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
DTH1_k127_86436_0	344747.PM8797T_17402	1.724e-154	497.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_86436_1	497964.CfE428DRAFT_0899	1.002e-127	420.0	COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
DTH1_k127_86436_3	1123376.AUIU01000011_gene924	1.047e-62	222.0	COG0118@1|root,COG0118@2|Bacteria,3J0K7@40117|Nitrospirae	40117|Nitrospirae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH1_k127_86436_2	1356854.N007_10430	3.238e-65	226.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH1_k127_8644753_2	497964.CfE428DRAFT_3334	1.959e-66	234.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH1_k127_8644753_0	497964.CfE428DRAFT_2596	5.165e-90	312.0	COG0402@1|root,COG0402@2|Bacteria,46TB5@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH1_k127_8644753_4	481448.Minf_1981	3.938e-09	64.0	COG1544@1|root,COG1544@2|Bacteria,46WSI@74201|Verrucomicrobia,37HA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
DTH1_k127_8644753_1	278957.ABEA03000097_gene778	6.315e-77	275.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,3K7TC@414999|Opitutae	414999|Opitutae	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DTH1_k127_8644753_3	278963.ATWD01000001_gene2445	1.177e-24	113.0	COG1018@1|root,COG1018@2|Bacteria,3Y3FD@57723|Acidobacteria,2JM1U@204432|Acidobacteriia	204432|Acidobacteriia	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,FAD_binding_6,Fer2,MOSC,NAD_binding_1
DTH1_k127_8658597_1	234267.Acid_7405	4.885e-58	213.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
DTH1_k127_8658597_0	616991.JPOO01000001_gene2853	5.951e-89	307.0	COG4409@1|root,COG4409@2|Bacteria,4PAPR@976|Bacteroidetes,1IF7B@117743|Flavobacteriia,23HKK@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_8658597_3	886293.Sinac_0556	2.497e-16	89.0	COG2165@1|root,COG2165@2|Bacteria,2IZ3B@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_8658597_2	1396141.BATP01000003_gene4864	2.671e-39	170.0	COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	2|Bacteria	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	oprH	-	3.2.1.4,3.2.1.73	ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449	ko00500,ko01100,ko05133,map00500,map01100,map05133	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko02000	1.B.14,1.B.14.2,1.B.40.2	GH5,GH9	-	Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3
DTH1_k127_8658597_4	1463879.JOHP01000017_gene2377	3.635e-10	70.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
DTH1_k127_8658597_5	234267.Acid_4454	9.705e-06	49.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_8712547_2	452637.Oter_0906	1.826e-10	66.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH1_k127_8712547_1	452637.Oter_2583	5.136e-88	299.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH1_k127_8712547_3	1123388.AQWU01000066_gene697	1.035e-05	55.0	2DRZU@1|root,33DVD@2|Bacteria,1WI81@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH1_k127_8719930_3	497964.CfE428DRAFT_2172	1.432e-33	133.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DTH1_k127_8719930_2	478741.JAFS01000001_gene1519	1.806e-36	139.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,37GX8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
DTH1_k127_8719930_1	485916.Dtox_1215	3.744e-101	349.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH1_k127_8719930_0	1156937.MFUM_940006	1.55e-110	369.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,37GAQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH1_k127_8722593_2	497964.CfE428DRAFT_3286	1.646e-34	145.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8722593_1	251229.Chro_1157	1.242e-67	235.0	COG1905@1|root,COG1905@2|Bacteria,1G54V@1117|Cyanobacteria,3VJR9@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
DTH1_k127_8722593_0	98439.AJLL01000016_gene1689	9.628e-246	767.0	COG1894@1|root,COG1894@2|Bacteria,1G2KY@1117|Cyanobacteria	1117|Cyanobacteria	C	NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit	hoxF	-	1.6.5.3	ko:K05587	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
DTH1_k127_8745680_1	670307.HYPDE_33213	5.269e-98	337.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
DTH1_k127_8745680_3	1173023.KE650771_gene1836	4.033e-24	113.0	COG1262@1|root,COG2944@1|root,COG1262@2|Bacteria,COG2944@2|Bacteria,1G0ZT@1117|Cyanobacteria	1117|Cyanobacteria	D	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
DTH1_k127_8745680_2	706587.Desti_1336	9.709e-25	110.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,42VEJ@68525|delta/epsilon subdivisions,2WS0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
DTH1_k127_8745680_0	452637.Oter_3479	1.945e-160	508.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
DTH1_k127_8751461_3	497964.CfE428DRAFT_2672	6.635e-61	212.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH1_k127_8751461_6	497964.CfE428DRAFT_2672	2.165e-11	66.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH1_k127_8751461_2	94624.Bpet1409	1.865e-66	236.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH1_k127_8751461_1	94624.Bpet1409	8.482e-164	535.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH1_k127_8751461_4	1366050.N234_27952	3.703e-32	132.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria,1KI6K@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
DTH1_k127_8751461_5	420324.KI911932_gene324	6.451e-19	90.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
DTH1_k127_8751461_0	395494.Galf_2787	1.63e-254	810.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,1P17M@1224|Proteobacteria,2WHHU@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat_2
DTH1_k127_8751461_7	35128.Thaps23576	0.0001803	47.0	2ENJE@1|root,2SRZD@2759|Eukaryota,2XGJZ@2836|Bacillariophyta	2836|Bacillariophyta	S	Helicase associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HA
DTH1_k127_8758497_1	886293.Sinac_2497	2.716e-45	186.0	COG1595@1|root,COG2373@1|root,COG1595@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K03088,ko:K06894	-	-	-	-	ko00000,ko03021	-	-	-	A2M_N,CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
DTH1_k127_8758497_0	1403819.BATR01000183_gene6316	1.37e-53	194.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,OMP_b-brl
DTH1_k127_8775683_1	1396141.BATP01000056_gene3278	2.749e-49	200.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
DTH1_k127_8775683_0	667632.KB890176_gene4536	2.186e-76	259.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1K0Y7@119060|Burkholderiaceae	28216|Betaproteobacteria	L	dna topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
DTH1_k127_8807509_2	1379698.RBG1_1C00001G0366	6.431e-07	60.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	Reg_prop,Y_Y_Y
DTH1_k127_8807509_0	485918.Cpin_0414	1.841e-60	212.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
DTH1_k127_8807509_1	794903.OPIT5_13650	1.667e-15	87.0	2AXAG@1|root,30YNX@2|Bacteria,46YVC@74201|Verrucomicrobia,3K96I@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8821273_0	497964.CfE428DRAFT_1905	1.035e-107	358.0	COG1045@1|root,COG1045@2|Bacteria,46S5J@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
DTH1_k127_8821273_1	477641.MODMU_0790	2.278e-07	55.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2I81M@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
DTH1_k127_8821273_2	1121287.AUMU01000010_gene1804	4.423e-05	57.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1IKPF@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
DTH1_k127_8821273_3	9713.XP_006733312.1	0.0001337	55.0	KOG0613@1|root,KOG4475@1|root,KOG0613@2759|Eukaryota,KOG4475@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata,48Y8I@7742|Vertebrata,3J1H6@40674|Mammalia,3EFX2@33554|Carnivora	33208|Metazoa	T	Titin Z	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
DTH1_k127_8863086_0	102125.Xen7305DRAFT_00043350	5.987e-112	384.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria,3VHP2@52604|Pleurocapsales	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH1_k127_8863086_1	28444.JODQ01000005_gene1401	3.552e-85	291.0	COG1572@1|root,COG2133@1|root,COG2374@1|root,COG3291@1|root,COG3828@1|root,COG1572@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4EKGY@85012|Streptosporangiales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	ASH,CBM_6,DUF1349,F5_F8_type_C,GSDH,PKD,Ricin_B_lectin,ThuA
DTH1_k127_8863086_2	452637.Oter_2056	7.827e-78	264.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
DTH1_k127_8863086_3	452637.Oter_2055	4.399e-54	192.0	COG4656@1|root,COG4656@2|Bacteria,46W83@74201|Verrucomicrobia	74201|Verrucomicrobia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
DTH1_k127_8868635_0	314230.DSM3645_06639	0.0	1191.0	COG2609@1|root,COG2609@2|Bacteria,2IXXY@203682|Planctomycetes	203682|Planctomycetes	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DTH1_k127_8868635_1	479434.Sthe_2682	2.334e-70	252.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
DTH1_k127_8870249_6	264203.ZMO0116	2.244e-27	117.0	COG1959@1|root,COG1959@2|Bacteria,1RGUG@1224|Proteobacteria,2UANJ@28211|Alphaproteobacteria,2K4GF@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH1_k127_8870249_5	1121920.AUAU01000009_gene1881	3.564e-31	143.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH1_k127_8870249_3	1121920.AUAU01000024_gene2381	2.926e-58	231.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DTH1_k127_8870249_0	243231.GSU2888	1.539e-161	528.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
DTH1_k127_8870249_1	1121920.AUAU01000024_gene2386	1.724e-116	381.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DTH1_k127_8870249_2	1121920.AUAU01000024_gene2384	5.547e-75	273.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
DTH1_k127_8876169_0	1349822.NSB1T_12810	5.893e-132	438.0	COG2189@1|root,COG2189@2|Bacteria,4NHTG@976|Bacteroidetes,2FQKU@200643|Bacteroidia,22YMU@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA methylase	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MerR,N6_N4_Mtase
DTH1_k127_8878361_0	886293.Sinac_7036	7.199e-176	559.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8878361_1	1245471.PCA10_37690	1.102e-18	93.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1SASQ@1236|Gammaproteobacteria,1YCT8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH1_k127_8889365_1	251221.35211558	1.871e-20	105.0	COG1404@1|root,COG2706@1|root,COG3391@1|root,COG1404@2|Bacteria,COG2706@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_S8,TIG,VCBS
DTH1_k127_8889365_0	1499967.BAYZ01000068_gene1988	5.261e-37	154.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH1_k127_8889365_2	1331060.RLDS_11615	7.511e-20	89.0	COG1993@1|root,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,2U9WX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
DTH1_k127_8894031_0	1396418.BATQ01000025_gene5262	7.062e-109	366.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,2IW1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH1_k127_8894031_1	240016.ABIZ01000001_gene4452	5.772e-105	350.0	COG1577@1|root,COG1577@2|Bacteria,46V85@74201|Verrucomicrobia	74201|Verrucomicrobia	I	mevalonate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH1_k127_8894031_2	234267.Acid_7362	7.727e-94	317.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	2|Bacteria	M	PFAM Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
DTH1_k127_8894031_4	290397.Adeh_3736	1.758e-10	66.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
DTH1_k127_8894031_3	497964.CfE428DRAFT_0566	2.672e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
DTH1_k127_8897959_0	697281.Mahau_1189	1.391e-160	527.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,42EMX@68295|Thermoanaerobacterales	186801|Clostridia	G	alpha-L-rhamnosidase domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH1_k127_8900438_0	583355.Caka_1736	4.417e-219	713.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_8901253_1	1167006.UWK_02169	1.738e-36	156.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH1_k127_8901253_0	1396418.BATQ01000113_gene4631	1.168e-118	392.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
DTH1_k127_8904921_2	448385.sce0471	9.449e-81	279.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
DTH1_k127_8904921_3	497964.CfE428DRAFT_3740	1.825e-15	77.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH1_k127_8904921_0	497964.CfE428DRAFT_3740	1.491e-180	572.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH1_k127_8904921_1	1096546.WYO_0480	3.784e-117	382.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2U1DA@28211|Alphaproteobacteria,1JTZ6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
DTH1_k127_8921779_1	886293.Sinac_0208	2.342e-06	58.0	COG2165@1|root,COG2165@2|Bacteria,2IX5U@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_8921779_0	278957.ABEA03000086_gene2490	3.364e-12	77.0	COG2165@1|root,COG2165@2|Bacteria,46Y25@74201|Verrucomicrobia,3K8TK@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_8927563_1	497964.CfE428DRAFT_4944	5.507e-40	153.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH1_k127_8927563_0	497964.CfE428DRAFT_4943	5.537e-168	567.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
DTH1_k127_8928275_0	335543.Sfum_1457	1.958e-246	784.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
DTH1_k127_8934016_3	497964.CfE428DRAFT_2334	2.344e-46	172.0	COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DTH1_k127_8934016_2	452637.Oter_2839	4.388e-150	484.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH1_k127_8934016_1	452637.Oter_3485	1.508e-230	739.0	COG2217@1|root,COG2217@2|Bacteria,46S53@74201|Verrucomicrobia,3K7EF@414999|Opitutae	414999|Opitutae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
DTH1_k127_8934016_4	1191523.MROS_2770	1.134e-32	135.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH1_k127_8934016_0	497964.CfE428DRAFT_6083	2.072e-286	894.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
DTH1_k127_8938751_9	1396141.BATP01000028_gene2285	1.989e-52	208.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
DTH1_k127_8938751_15	1303518.CCALI_00378	3.777e-17	92.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_8938751_12	1444309.JAQG01000181_gene3484	8.357e-34	147.0	COG2833@1|root,COG2833@2|Bacteria,1W5BJ@1239|Firmicutes,4I0UF@91061|Bacilli,26VKN@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
DTH1_k127_8938751_8	1499967.BAYZ01000017_gene6249	9.326e-63	229.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_8938751_5	97139.C824_01928	2.167e-86	300.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_8938751_10	497964.CfE428DRAFT_2346	2.271e-52	198.0	COG3694@1|root,COG3694@2|Bacteria,46VPX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
DTH1_k127_8938751_6	497964.CfE428DRAFT_2347	1.405e-71	251.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
DTH1_k127_8938751_0	1519464.HY22_04590	4.086e-242	768.0	COG0058@1|root,COG0058@2|Bacteria,1FD8Y@1090|Chlorobi	1090|Chlorobi	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
DTH1_k127_8938751_1	886293.Sinac_6975	8.02e-154	500.0	28KPG@1|root,2ZA7K@2|Bacteria,2J1E2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8938751_4	521674.Plim_2302	2.149e-93	321.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DTH1_k127_8938751_3	240016.ABIZ01000001_gene4766	5.514e-119	390.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH1_k127_8938751_14	497964.CfE428DRAFT_4596	2.342e-21	110.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283,ko:K02454,ko:K03220,ko:K03466	ko03070,ko05111,map03070,map05111	M00331,M00332	-	-	ko00000,ko00001,ko00002,ko02035,ko02044,ko03036	3.A.12,3.A.15,3.A.6.1	-	-	Cytochrom_c3_2,FHA,FtsK_SpoIIIE,Response_reg,T2SSE,Yop-YscD_cpl,Yop-YscD_ppl
DTH1_k127_8938751_13	497964.CfE428DRAFT_5353	1.199e-23	118.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH1_k127_8938751_11	452637.Oter_0887	1.597e-44	183.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8938751_7	497964.CfE428DRAFT_5952	3.307e-71	250.0	COG0745@1|root,COG0745@2|Bacteria,46V5I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH1_k127_8938751_2	497964.CfE428DRAFT_5953	2.313e-120	408.0	COG0642@1|root,COG2205@2|Bacteria,46Z6V@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH1_k127_8938751_16	1112217.PPL19_20816	2.813e-12	76.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_32,rve
DTH1_k127_8943879_8	349741.Amuc_0030	1.631e-119	396.0	COG2334@1|root,COG2334@2|Bacteria,46TIS@74201|Verrucomicrobia,2IVEV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
DTH1_k127_8943879_3	452637.Oter_0886	8.855e-139	449.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DTH1_k127_8943879_14	118005.AWNK01000005_gene1565	2.476e-46	177.0	COG0290@1|root,COG0290@2|Bacteria	2|Bacteria	J	translation initiation factor activity	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DTH1_k127_8943879_2	1396418.BATQ01000079_gene806	4.782e-178	567.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,2IU2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DTH1_k127_8943879_12	105559.Nwat_0649	7.133e-58	207.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1WY7B@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH1_k127_8943879_13	1042209.HK44_007325	1.478e-49	180.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DTH1_k127_8943879_4	794903.OPIT5_30480	1.355e-136	447.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
DTH1_k127_8943879_16	497964.CfE428DRAFT_5124	5.105e-25	109.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,LytTR,PAS,PAS_3,PAS_9,Response_reg,dCache_1
DTH1_k127_8943879_17	497964.CfE428DRAFT_1483	1.495e-06	49.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH1_k127_8943879_11	497964.CfE428DRAFT_5394	3.474e-60	230.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
DTH1_k127_8943879_1	497964.CfE428DRAFT_1483	1.028e-212	667.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH1_k127_8943879_9	215803.DB30_6514	2.153e-74	263.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YYHJ@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH1_k127_8943879_0	671143.DAMO_0980	5.471e-278	870.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH1_k127_8943879_7	234267.Acid_4784	1.454e-128	426.0	COG0591@1|root,COG0591@2|Bacteria,3Y419@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH1_k127_8943879_5	1403819.BATR01000098_gene3267	2.176e-135	439.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,2ITU4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
DTH1_k127_8943879_6	452637.Oter_1656	6.985e-133	427.0	COG2013@1|root,COG2013@2|Bacteria,46SY6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
DTH1_k127_8943879_10	661478.OP10G_3898	4.019e-70	250.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
DTH1_k127_8943879_15	1210884.HG799462_gene8039	1.882e-44	173.0	COG0845@1|root,COG0845@2|Bacteria,2IYMS@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH1_k127_8943879_18	2423.NA23_0209590	0.0002641	51.0	COG1413@1|root,COG1413@2|Bacteria,2GDN4@200918|Thermotogae	200918|Thermotogae	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
DTH1_k127_8961171_0	661478.OP10G_2626	2.904e-158	521.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
DTH1_k127_8961171_1	313628.LNTAR_00950	2.264e-121	410.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH1_k127_8969901_0	497964.CfE428DRAFT_2506	1.493e-219	685.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DTH1_k127_8969901_1	344747.PM8797T_15161	1.412e-62	225.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_8975844_0	794903.OPIT5_03555	2.278e-103	348.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
DTH1_k127_8975844_1	497964.CfE428DRAFT_2938	2.021e-92	320.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH1_k127_8975844_3	1121472.AQWN01000001_gene239	2.161e-41	164.0	COG2859@1|root,COG2859@2|Bacteria,1V1Q4@1239|Firmicutes,24GEE@186801|Clostridia,264GJ@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
DTH1_k127_8975844_2	635013.TherJR_2166	8.875e-54	196.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,260BS@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH1_k127_8978166_1	497964.CfE428DRAFT_5897	1.525e-130	438.0	COG1073@1|root,COG1073@2|Bacteria,46TMQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8978166_3	502025.Hoch_2530	8.318e-75	265.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42MPE@68525|delta/epsilon subdivisions,2X630@28221|Deltaproteobacteria,2Z38I@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH1_k127_8978166_0	502025.Hoch_2529	0.0	1186.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DTH1_k127_8978166_2	502025.Hoch_2528	6.975e-116	388.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DTH1_k127_8978726_2	324602.Caur_0299	1.476e-16	89.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
DTH1_k127_8978726_3	1121116.KB894765_gene643	0.000426	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,4AAY1@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
DTH1_k127_8978726_0	497964.CfE428DRAFT_0845	7.737e-120	392.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH1_k127_8978726_1	1396418.BATQ01000139_gene3235	1.781e-24	107.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,2ITW4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH1_k127_8979095_6	497964.CfE428DRAFT_1385	3.793e-16	83.0	COG3344@1|root,COG3344@2|Bacteria,46SUD@74201|Verrucomicrobia	2|Bacteria	L	Group II intron maturase-specific domain protein	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
DTH1_k127_8979095_4	713587.THITH_06000	4.619e-26	113.0	COG1569@1|root,COG1569@2|Bacteria,1NJ68@1224|Proteobacteria,1SAF3@1236|Gammaproteobacteria,1X17S@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
DTH1_k127_8979095_7	323098.Nwi_0269	9.838e-08	55.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2TQQA@28211|Alphaproteobacteria,3JZMK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,HsdM_N,N6_Mtase
DTH1_k127_8979095_8	682795.AciX8_1742	0.0007648	49.0	COG2165@1|root,COG2165@2|Bacteria,3Y4X6@57723|Acidobacteria,2JJEP@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
DTH1_k127_8979095_3	536233.CLO_0602	1.588e-30	128.0	COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1UKZ5@1239|Firmicutes,24X63@186801|Clostridia,36R4U@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
DTH1_k127_8979095_0	518766.Rmar_1740	3.699e-107	364.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_8979095_1	365046.Rta_00040	6.006e-67	230.0	COG0286@1|root,COG0286@2|Bacteria,1NN38@1224|Proteobacteria,2VNIU@28216|Betaproteobacteria,4AGSN@80864|Comamonadaceae	28216|Betaproteobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
DTH1_k127_8979095_5	331678.Cphamn1_0748	3.839e-21	93.0	COG0286@1|root,COG0286@2|Bacteria,1FERX@1090|Chlorobi	1090|Chlorobi	H	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
DTH1_k127_8979095_2	509191.AEDB02000022_gene2935	6.015e-43	162.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
DTH1_k127_8984758_2	1254432.SCE1572_38850	5.9e-75	270.0	COG0564@1|root,COG1092@1|root,COG0564@2|Bacteria,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2WPIN@28221|Deltaproteobacteria,2Z02J@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PseudoU_synth_2
DTH1_k127_8984758_0	452637.Oter_1454	0.0	1373.0	COG0841@1|root,COG0841@2|Bacteria,46SER@74201|Verrucomicrobia	74201|Verrucomicrobia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH1_k127_8984758_3	452637.Oter_1455	4.469e-63	231.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH1_k127_8984758_1	452637.Oter_1456	5.723e-83	295.0	COG1538@1|root,COG1538@2|Bacteria,46TY1@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH1_k127_8984758_4	1056820.KB900646_gene3544	5.229e-20	92.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,2PQGZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH1_k127_8984758_6	1168289.AJKI01000035_gene3570	4.022e-12	68.0	2AD45@1|root,312SH@2|Bacteria,4PHQV@976|Bacteroidetes,2G1PE@200643|Bacteroidia,3XKFZ@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_8984758_5	926566.Terro_2606	4.368e-19	90.0	COG0640@1|root,COG0640@2|Bacteria,3Y5UV@57723|Acidobacteria,2JNP2@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DTH1_k127_8995533_2	583355.Caka_1376	9.108e-52	190.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46UY4@74201|Verrucomicrobia,3K7AN@414999|Opitutae	414999|Opitutae	K	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
DTH1_k127_8995533_1	497964.CfE428DRAFT_2088	6.435e-196	616.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DTH1_k127_8995533_0	278957.ABEA03000091_gene684	2.944e-252	784.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH1_k127_8998031_0	240016.ABIZ01000001_gene3005	1.683e-70	241.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH1_k127_8998031_2	452637.Oter_1439	3.572e-20	96.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
DTH1_k127_8998031_1	240016.ABIZ01000001_gene760	2.19e-32	138.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like,Usp
DTH1_k127_9020682_2	886293.Sinac_1932	3.781e-102	361.0	COG2706@1|root,COG2706@2|Bacteria,2J55E@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH1_k127_9020682_3	543728.Vapar_2851	1.9e-58	205.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2WBQC@28216|Betaproteobacteria,4AI59@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH1_k127_9020682_5	1403819.BATR01000182_gene6270	2.4e-27	129.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,2IUR7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
DTH1_k127_9020682_6	56107.Cylst_5717	1.232e-14	87.0	COG1413@1|root,COG1672@1|root,COG1413@2|Bacteria,COG1672@2|Bacteria,1G2R4@1117|Cyanobacteria,1HMQH@1161|Nostocales	1117|Cyanobacteria	CT	HEAT repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
DTH1_k127_9020682_7	382464.ABSI01000005_gene1329	7.226e-09	61.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
DTH1_k127_9020682_4	945713.IALB_1744	4.814e-45	168.0	COG0691@1|root,COG0691@2|Bacteria	2|Bacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DTH1_k127_9020682_1	794903.OPIT5_26245	4.234e-188	613.0	COG4796@1|root,COG4796@2|Bacteria,46Y4X@74201|Verrucomicrobia,3K8XV@414999|Opitutae	414999|Opitutae	U	Bacterial type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
DTH1_k127_9020682_8	1210884.HG799463_gene10210	8.237e-09	68.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DTH1_k127_9020682_10	794903.OPIT5_26235	0.000419	52.0	2A3EY@1|root,31MUJ@2|Bacteria,46X6D@74201|Verrucomicrobia,3K9KW@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9020682_0	794903.OPIT5_26225	1.043e-195	626.0	COG2804@1|root,COG2804@2|Bacteria,46XZ0@74201|Verrucomicrobia,3K8NA@414999|Opitutae	414999|Opitutae	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
DTH1_k127_9020682_9	880072.Desac_2275	3.036e-06	50.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MSC9@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
DTH1_k127_9021298_0	452637.Oter_1374	2.457e-80	272.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
DTH1_k127_9026030_2	497964.CfE428DRAFT_4863	1.268e-104	379.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9026030_3	497964.CfE428DRAFT_4864	1.823e-65	236.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9026030_1	1217720.ALOX01000026_gene3512	5.083e-139	456.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPSC@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH1_k127_9026030_0	497964.CfE428DRAFT_1010	3.1e-173	554.0	COG0277@1|root,COG0277@2|Bacteria,46S85@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DTH1_k127_9026527_2	1340493.JNIF01000004_gene823	0.0004217	42.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH1_k127_9026527_1	1550091.JROE01000002_gene502	2.071e-93	322.0	2DBWR@1|root,2ZBIN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
DTH1_k127_9026527_0	497964.CfE428DRAFT_6195	1.529e-114	376.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_9031448_0	481448.Minf_1559	2.028e-306	959.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,37G1Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
DTH1_k127_9036611_3	383372.Rcas_0864	6.122e-11	74.0	COG0318@1|root,COG0318@2|Bacteria,2GBKJ@200795|Chloroflexi,3781K@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9036611_1	1123070.KB899254_gene1274	3.935e-61	217.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia,2IU8D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind,Peptidase_S24
DTH1_k127_9036611_2	1123508.JH636440_gene2371	4.646e-34	134.0	2CCSR@1|root,32RWC@2|Bacteria,2J1M5@203682|Planctomycetes	203682|Planctomycetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH1_k127_9036611_0	452637.Oter_3175	6.919e-86	300.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia,3K7SQ@414999|Opitutae	414999|Opitutae	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DTH1_k127_9052434_4	180332.JTGN01000022_gene1511	2.28e-62	228.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24G9W@186801|Clostridia	186801|Clostridia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_9052434_6	530564.Psta_0778	4.661e-39	149.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DTH1_k127_9052434_2	452637.Oter_0669	1.082e-118	385.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
DTH1_k127_9052434_1	452637.Oter_0670	0.0	1015.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH1_k127_9052434_5	583355.Caka_1740	3.076e-46	177.0	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
DTH1_k127_9052434_7	1125863.JAFN01000001_gene2910	5.401e-35	143.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
DTH1_k127_9052434_0	118168.MC7420_356	0.0	1086.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1H87F@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH1_k127_9052434_9	395493.BegalDRAFT_0545	3.625e-21	99.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
DTH1_k127_9052434_3	555079.Toce_0685	1.631e-96	332.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH1_k127_9052434_10	1123277.KB893217_gene4667	4.866e-19	91.0	COG2405@1|root,COG2405@2|Bacteria,4NVKA@976|Bacteroidetes,47X58@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
DTH1_k127_9052434_12	489825.LYNGBM3L_48350	1.164e-06	53.0	COG2405@1|root,COG2405@2|Bacteria,1G725@1117|Cyanobacteria,1HATZ@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
DTH1_k127_9052434_11	1209989.TepiRe1_1613	5.922e-15	77.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH1_k127_9052805_3	215803.DB30_5279	8.514e-49	185.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria,2YUCY@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
DTH1_k127_9052805_0	1123242.JH636435_gene2020	8.23e-271	842.0	COG2407@1|root,COG2407@2|Bacteria,2IXT8@203682|Planctomycetes	203682|Planctomycetes	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9052805_4	926566.Terro_1693	5.692e-17	88.0	COG2823@1|root,COG2823@2|Bacteria,3Y4FV@57723|Acidobacteria,2JJ5I@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
DTH1_k127_9052805_1	1304885.AUEY01000019_gene1169	1.136e-135	457.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DTH1_k127_9052805_2	497964.CfE428DRAFT_5778	6.304e-103	344.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
DTH1_k127_9061948_2	1265505.ATUG01000001_gene4678	5.276e-21	109.0	COG0584@1|root,COG1409@1|root,COG0584@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GDPD_2,Metallophos,Pur_ac_phosph_N
DTH1_k127_9061948_0	497964.CfE428DRAFT_2458	2.713e-80	277.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH1_k127_9061948_1	452637.Oter_1107	3.384e-35	138.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
DTH1_k127_9070610_4	90813.JQMT01000001_gene1896	1.208e-16	90.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,462JF@72273|Thiotrichales	72273|Thiotrichales	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
DTH1_k127_9070610_5	610130.Closa_1802	0.0001348	45.0	COG2515@1|root,COG2515@2|Bacteria,1UDCW@1239|Firmicutes,24BXZ@186801|Clostridia,220EC@1506553|Lachnoclostridium	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
DTH1_k127_9070610_3	1380391.JIAS01000012_gene4181	7.406e-22	100.0	COG4566@1|root,COG4566@2|Bacteria,1N5R5@1224|Proteobacteria,2UE41@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH1_k127_9070610_2	443598.AUFA01000003_gene2204	1.362e-58	212.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,3JQPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH1_k127_9070610_0	335543.Sfum_0581	9.247e-94	347.0	COG2202@1|root,COG2984@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3
DTH1_k127_9070610_1	1121413.JMKT01000008_gene1013	2.681e-63	249.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
DTH1_k127_9076041_2	497964.CfE428DRAFT_4167	1.085e-76	263.0	COG1208@1|root,COG1208@2|Bacteria,46SP1@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH1_k127_9076041_4	382464.ABSI01000012_gene2250	4.804e-51	184.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DTH1_k127_9076041_5	1341157.RF007C_09585	7.408e-41	156.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DTH1_k127_9076041_0	497964.CfE428DRAFT_2151	1.98e-130	425.0	COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH1_k127_9076041_1	497964.CfE428DRAFT_2167	1.735e-105	360.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
DTH1_k127_9076041_3	886293.Sinac_5728	6.485e-72	248.0	COG2264@1|root,COG2264@2|Bacteria,2J3H0@203682|Planctomycetes	203682|Planctomycetes	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH1_k127_9076041_6	1158294.JOMI01000004_gene3543	7.606e-27	115.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,2FSDK@200643|Bacteroidia	976|Bacteroidetes	G	SMP-30 Gluconolaconase LRE-like	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pectate_lyase_3,SGL
DTH1_k127_9085105_1	1382306.JNIM01000001_gene2623	3.823e-31	126.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH1_k127_9085105_2	1123070.KB899249_gene301	4.115e-11	72.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,2IUVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DTH1_k127_9085105_0	1120973.AQXL01000133_gene1776	5.295e-167	546.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,2783C@186823|Alicyclobacillaceae	91061|Bacilli	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH
DTH1_k127_9099046_2	497964.CfE428DRAFT_2419	8.221e-50	181.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia	74201|Verrucomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
DTH1_k127_9099046_0	1123242.JH636434_gene4856	1.13e-202	645.0	COG0591@1|root,COG0591@2|Bacteria,2J2KC@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH1_k127_9099046_1	1156935.QWE_19483	1.367e-92	315.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4B993@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	gluconolactonase	-	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
DTH1_k127_9099752_0	1117108.PAALTS15_29431	7.706e-111	370.0	COG3669@1|root,COG3669@2|Bacteria,1TSG7@1239|Firmicutes,4HEKS@91061|Bacilli,26UH5@186822|Paenibacillaceae	91061|Bacilli	G	alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH1_k127_9099752_1	313606.M23134_04526	6.126e-100	351.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,47NSK@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
DTH1_k127_9099752_2	1492737.FEM08_22110	5.205e-40	155.0	COG2273@1|root,COG2273@2|Bacteria,4NTIB@976|Bacteroidetes	976|Bacteroidetes	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_67N
DTH1_k127_9129962_3	1038859.AXAU01000066_gene2279	0.0008041	47.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
DTH1_k127_9129962_2	1396141.BATP01000022_gene455	1.409e-08	68.0	COG4675@1|root,COG4675@2|Bacteria,46X85@74201|Verrucomicrobia,2IUYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
DTH1_k127_9129962_1	1396141.BATP01000040_gene2082	3.871e-16	93.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH1_k127_9129962_0	1303518.CCALI_02122	9.588e-222	728.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9130975_2	234267.Acid_5934	1.286e-05	48.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y46C@57723|Acidobacteria	57723|Acidobacteria	EG	PFAM RhaT l-rhamnose-proton symport 2	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
DTH1_k127_9130975_0	1123278.KB893616_gene3404	2.651e-213	679.0	COG3408@1|root,COG3408@2|Bacteria,4NHST@976|Bacteroidetes,47KY3@768503|Cytophagia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
DTH1_k127_9130975_1	1396141.BATP01000004_gene5925	5.311e-37	151.0	COG3250@1|root,COG4692@1|root,COG3250@2|Bacteria,COG4692@2|Bacteria,46Z9T@74201|Verrucomicrobia,2IWDF@203494|Verrucomicrobiae	2|Bacteria	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
DTH1_k127_9131395_1	386456.JQKN01000006_gene1261	6.002e-58	214.0	COG3177@1|root,arCOG03110@2157|Archaea,2XUN8@28890|Euryarchaeota,23PGE@183925|Methanobacteria	183925|Methanobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
DTH1_k127_9131395_3	930171.Asphe3_35720	2.379e-14	76.0	COG0347@1|root,COG0347@2|Bacteria,2H6FT@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9131395_0	1122221.JHVI01000015_gene1707	4.611e-104	349.0	COG3329@1|root,COG3329@2|Bacteria,1WJER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
DTH1_k127_9131395_2	765420.OSCT_1289	2.801e-24	104.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,375UD@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DTH1_k127_9146595_0	452637.Oter_1389	1.512e-152	493.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_9146595_4	1396141.BATP01000060_gene4559	4.188e-34	146.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
DTH1_k127_9146595_2	497964.CfE428DRAFT_4864	5.459e-64	228.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9146595_1	314230.DSM3645_23076	2.269e-123	412.0	COG1520@1|root,COG1520@2|Bacteria,2IXN8@203682|Planctomycetes	203682|Planctomycetes	S	serine threonine protein kinase afsK	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_9146595_3	497964.CfE428DRAFT_0226	1.547e-50	185.0	COG0663@1|root,COG0663@2|Bacteria	2|Bacteria	G	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH1_k127_9146595_5	481448.Minf_1726	7.066e-31	126.0	COG2220@1|root,COG2220@2|Bacteria,46UIR@74201|Verrucomicrobia,37GGK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DTH1_k127_9164246_4	740709.A10D4_00975	1.814e-11	76.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
DTH1_k127_9164246_1	744872.Spica_1624	5.066e-37	148.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH1_k127_9164246_3	1123242.JH636435_gene1423	6.438e-14	82.0	COG4968@1|root,COG4968@2|Bacteria,2IZKQ@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_9164246_5	1051985.l11_21780	1.121e-10	70.0	COG0863@1|root,COG0863@2|Bacteria,1R4QN@1224|Proteobacteria,2VP1E@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_N,N6_N4_Mtase
DTH1_k127_9164246_0	509191.AEDB02000022_gene2935	1.791e-107	372.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
DTH1_k127_9164246_2	1048983.EL17_05185	8.997e-20	94.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47MGE@768503|Cytophagia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
DTH1_k127_9173036_1	234267.Acid_0094	1.283e-151	485.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE23	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH1_k127_9173036_0	497964.CfE428DRAFT_4764	2.074e-205	657.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH1_k127_919808_0	382464.ABSI01000005_gene1189	7.204e-70	269.0	COG2312@1|root,COG5337@1|root,COG2312@2|Bacteria,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_919808_1	1396141.BATP01000059_gene2521	3.476e-20	107.0	COG2133@1|root,COG2931@1|root,COG3055@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,4.2.2.2	ko:K00428,ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin,fn3
DTH1_k127_9205405_1	452637.Oter_4595	1.201e-62	217.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,3K740@414999|Opitutae	414999|Opitutae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH1_k127_9205405_2	1117108.PAALTS15_19168	3.857e-08	64.0	COG0726@1|root,COG3291@1|root,COG5184@1|root,COG5276@1|root,COG5434@1|root,COG0726@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5434@2|Bacteria,1UYD0@1239|Firmicutes,4HVHQ@91061|Bacilli,26U3Z@186822|Paenibacillaceae	91061|Bacilli	M	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C
DTH1_k127_9205405_0	1245471.PCA10_41050	3.878e-79	282.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RYKY@1236|Gammaproteobacteria,1YFQD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH1_k127_9209046_2	1382359.JIAL01000001_gene680	3.636e-20	100.0	COG0719@1|root,COG0719@2|Bacteria,3Y4EK@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
DTH1_k127_9209046_0	1156937.MFUM_90002	1.721e-193	615.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia,37G3Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH1_k127_9209046_1	382464.ABSI01000006_gene874	2.621e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_924045_0	926550.CLDAP_07020	2.27e-115	377.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
DTH1_k127_924045_1	240016.ABIZ01000001_gene5629	5.62e-57	208.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	CP_0628	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2,VIT
DTH1_k127_924045_2	349741.Amuc_0982	7.096e-07	59.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DNase_NucA_NucB,Endonuclea_NS_2,RHS_repeat
DTH1_k127_9256167_3	478741.JAFS01000002_gene271	2.168e-40	153.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,37GTE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	rnhD	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DTH1_k127_9256167_0	1396141.BATP01000027_gene1172	1.925e-97	326.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,2IU7R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_1
DTH1_k127_9256167_1	1121918.ARWE01000001_gene1522	1.224e-47	175.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,43W09@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
DTH1_k127_9256167_2	497964.CfE428DRAFT_2042	1.172e-45	166.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH1_k127_9256607_2	1042326.AZNV01000065_gene5684	8.327e-06	50.0	COG0784@1|root,COG2199@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4B88G@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
DTH1_k127_9256607_1	743719.PaelaDRAFT_1789	2.555e-10	72.0	COG2207@1|root,COG2207@2|Bacteria,1UMYK@1239|Firmicutes,4IU3F@91061|Bacilli,277HV@186822|Paenibacillaceae	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
DTH1_k127_9256607_0	497964.CfE428DRAFT_2773	2.609e-47	184.0	2F6K4@1|root,33Z30@2|Bacteria,46VYC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
DTH1_k127_9284512_1	1265505.ATUG01000001_gene3993	7.911e-63	227.0	COG4313@1|root,COG4313@2|Bacteria,1R6GU@1224|Proteobacteria,43BI4@68525|delta/epsilon subdivisions,2X6WJ@28221|Deltaproteobacteria,2MKN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DTH1_k127_9284512_0	452637.Oter_0816	4.274e-196	616.0	COG1350@1|root,COG1350@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH1_k127_9293011_0	761193.Runsl_1895	8.395e-155	501.0	COG1520@1|root,COG1520@2|Bacteria,4NK4X@976|Bacteroidetes,47KWI@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9293011_1	1340493.JNIF01000003_gene3009	3.164e-127	423.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Oxidoreduct_C,PmoA
DTH1_k127_9293011_2	1173026.Glo7428_3849	1.182e-19	91.0	COG1724@1|root,COG1724@2|Bacteria,1G9Z7@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DTH1_k127_9293011_3	111780.Sta7437_3418	1.77e-18	89.0	COG1598@1|root,COG1598@2|Bacteria,1GAU7@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9305368_3	1396141.BATP01000023_gene554	1.031e-18	90.0	COG2340@1|root,COG2340@2|Bacteria,46VC3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
DTH1_k127_9305368_2	497964.CfE428DRAFT_5401	8.045e-82	289.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_9305368_1	497964.CfE428DRAFT_5401	1.681e-90	316.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH1_k127_9305368_0	497964.CfE428DRAFT_5400	5.344e-92	308.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_9320015_0	204669.Acid345_0658	2.42e-56	214.0	COG2159@1|root,COG2159@2|Bacteria,3Y2HY@57723|Acidobacteria,2JI2D@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH1_k127_9320015_1	1267535.KB906767_gene1160	3.105e-30	136.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH1_k127_9320015_3	3067.XP_002958057.1	0.0005033	50.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,34IKN@3041|Chlorophyta	3041|Chlorophyta	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
DTH1_k127_9320015_2	1123242.JH636434_gene4965	1.209e-16	84.0	COG0477@1|root,COG2814@2|Bacteria,2IYPH@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH1_k127_9333690_1	1499967.BAYZ01000095_gene4060	8.973e-106	347.0	COG4806@1|root,COG4806@2|Bacteria	2|Bacteria	G	L-rhamnose isomerase activity	rhaA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575	2.7.1.5,5.3.1.14	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R02437,R03014	RC00002,RC00017,RC00434	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3092,iUMNK88_1353.UMNK88_4739	RhaA
DTH1_k127_9333690_0	234267.Acid_5934	1.824e-132	431.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y46C@57723|Acidobacteria	57723|Acidobacteria	EG	PFAM RhaT l-rhamnose-proton symport 2	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
DTH1_k127_9338146_1	1121904.ARBP01000026_gene692	3.577e-69	237.0	COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes,47KN3@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH1_k127_9338146_0	481448.Minf_1705	1.778e-132	439.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,37G39@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine protease	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
DTH1_k127_9346182_2	469371.Tbis_2457	1.025e-12	69.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4DX9V@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
DTH1_k127_9346182_1	635013.TherJR_0182	2.142e-48	182.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
DTH1_k127_9346182_3	1396141.BATP01000023_gene664	4.698e-07	62.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
DTH1_k127_9346182_0	1157708.KB907454_gene2941	2.574e-67	242.0	COG4447@1|root,COG4886@1|root,COG4447@2|Bacteria,COG4886@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9355676_0	411477.PARMER_03655	3.732e-202	656.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH1_k127_9357611_0	306281.AJLK01000140_gene1050	2.31e-88	308.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1JHUP@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
DTH1_k127_9357611_1	1173026.Glo7428_2699	1.393e-52	193.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH1_k127_9357611_3	1121921.KB898706_gene2841	3.65e-32	144.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
DTH1_k127_9357611_2	927677.ALVU02000001_gene1764	3.247e-39	166.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1GR0B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
DTH1_k127_9380017_7	118166.JH976537_gene2586	2.73e-13	70.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria,1H76Y@1150|Oscillatoriales	1117|Cyanobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
DTH1_k127_9380017_5	358396.C445_20550	2.407e-56	207.0	COG0451@1|root,arCOG03095@2157|Archaea,2XTPI@28890|Euryarchaeota,23STT@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
DTH1_k127_9380017_2	382464.ABSI01000011_gene3025	1.287e-130	426.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH1_k127_9380017_4	1232410.KI421415_gene3077	9.357e-73	254.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
DTH1_k127_9380017_8	1484460.JSWG01000009_gene451	1.379e-12	77.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4NINJ@976|Bacteroidetes,1HZEY@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	LTD
DTH1_k127_9380017_6	278957.ABEA03000149_gene4042	5.435e-19	88.0	2BGYY@1|root,32AZ2@2|Bacteria,46ZHP@74201|Verrucomicrobia,3K9QU@414999|Opitutae	414999|Opitutae	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH1_k127_9380017_3	497964.CfE428DRAFT_2620	6.139e-117	382.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH1_k127_9380017_1	497964.CfE428DRAFT_2621	3.562e-165	529.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
DTH1_k127_9380017_0	864051.BurJ1DRAFT_3700	2.315e-166	576.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
DTH1_k127_9380787_1	886293.Sinac_2090	4.733e-107	353.0	COG0823@1|root,COG0823@2|Bacteria,2IZ00@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
DTH1_k127_9380787_4	1121468.AUBR01000005_gene35	1.65e-10	74.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,42H0N@68295|Thermoanaerobacterales	186801|Clostridia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
DTH1_k127_9380787_0	382464.ABSI01000006_gene864	1.718e-160	512.0	COG1225@1|root,COG1225@2|Bacteria,46TJA@74201|Verrucomicrobia,2ITIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH1_k127_9380787_6	866771.HMPREF9296_1795	4.144e-07	64.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
DTH1_k127_9380787_5	56780.SYN_03067	3.287e-10	68.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SmpA_OmlA,SusD-like_3
DTH1_k127_9380787_2	323259.Mhun_0476	8.595e-62	222.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
DTH1_k127_9385089_0	765420.OSCT_3130	4.226e-66	258.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
DTH1_k127_9385201_1	583355.Caka_1978	6.276e-71	247.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,3K72S@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH1_k127_9385201_2	794903.OPIT5_07630	2.927e-44	166.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,3K8IG@414999|Opitutae	414999|Opitutae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
DTH1_k127_9385201_0	497964.CfE428DRAFT_2609	1.011e-169	545.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH1_k127_9395449_0	935863.AWZR01000001_gene1970	4.623e-115	374.0	COG2382@1|root,COG2382@2|Bacteria,1NFUS@1224|Proteobacteria,1T816@1236|Gammaproteobacteria,1XA10@135614|Xanthomonadales	135614|Xanthomonadales	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
DTH1_k127_9395449_2	497964.CfE428DRAFT_3172	1.796e-44	166.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yitI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DTH1_k127_9395449_3	794903.OPIT5_14770	4.767e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_9395449_1	298654.FraEuI1c_4826	1.91e-61	230.0	COG2234@1|root,COG2234@2|Bacteria,2GJ67@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH1_k127_9395808_7	324602.Caur_0004	0.0004828	44.0	COG0515@1|root,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi,3751T@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH1_k127_9395808_5	497964.CfE428DRAFT_4502	6.107e-27	114.0	COG0607@1|root,COG0607@2|Bacteria,46W9V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH1_k127_9395808_6	497964.CfE428DRAFT_3831	1.861e-16	88.0	2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
DTH1_k127_9395808_3	1156937.MFUM_270037	4.083e-51	194.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,37GE7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_16,TPR_6,YfiO
DTH1_k127_9395808_8	497964.CfE428DRAFT_0660	0.0007884	49.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1542,DUF349,DUF4446,FIVAR,GA,Gram_pos_anchor,PhageMin_Tail
DTH1_k127_9395808_0	497964.CfE428DRAFT_1395	2.938e-131	446.0	COG1262@1|root,COG1262@2|Bacteria,46UX3@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PSCyt1
DTH1_k127_9395808_2	521674.Plim_0037	1.817e-92	320.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_9395808_1	886293.Sinac_4427	7.129e-108	360.0	COG3023@1|root,COG3023@2|Bacteria,2J257@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
DTH1_k127_9395808_4	886293.Sinac_2846	1.871e-29	118.0	COG4102@1|root,COG4102@2|Bacteria,2IX5I@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_9412373_0	28072.Nos7524_1372	2.609e-49	203.0	COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G1WI@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin,Calx-beta,PPC
DTH1_k127_9412373_2	1121887.AUDK01000004_gene431	3.497e-06	61.0	COG2911@1|root,COG3210@1|root,COG3533@1|root,COG4625@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,4PPKP@976|Bacteroidetes,1IKQ3@117743|Flavobacteriia,2P0T3@237|Flavobacterium	976|Bacteroidetes	U	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Laminin_G_3
DTH1_k127_941330_3	626887.J057_15190	2.127e-12	71.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,469WN@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
DTH1_k127_941330_0	481448.Minf_1629	2.849e-40	160.0	COG0491@1|root,COG0491@2|Bacteria,46S7X@74201|Verrucomicrobia,37GB4@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH1_k127_941330_4	1122176.KB903531_gene3073	6.053e-11	76.0	COG2312@1|root,COG2312@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
DTH1_k127_941330_2	1408473.JHXO01000006_gene1129	5.786e-14	85.0	COG3211@1|root,COG4935@1|root,COG3211@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,2G16U@200643|Bacteroidia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH1_k127_941330_1	1396141.BATP01000057_gene3053	6.235e-15	89.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH1_k127_9434224_0	1267535.KB906767_gene1026	1.138e-71	261.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_9450166_0	1123242.JH636438_gene5875	2.327e-145	468.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH1_k127_9450166_1	382464.ABSI01000013_gene1546	3.247e-23	110.0	COG5036@1|root,COG5036@2|Bacteria,46VA7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH1_k127_9450166_2	1144932.ATTF01000017_gene1171	9.049e-23	107.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
DTH1_k127_9450166_3	1114964.L485_15215	8.707e-08	60.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales	204457|Sphingomonadales	V	Secretion protein, HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH1_k127_9458023_2	1167006.UWK_00745	1.211e-42	160.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2MJBE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH1_k127_9458023_3	240015.ACP_0051	7.958e-15	78.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
DTH1_k127_9458023_1	583355.Caka_0776	1.296e-142	459.0	COG0714@1|root,COG0714@2|Bacteria,46SC8@74201|Verrucomicrobia,3K7W0@414999|Opitutae	414999|Opitutae	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH1_k127_9458023_0	497964.CfE428DRAFT_4579	2.386e-183	583.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH1_k127_9462392_1	502025.Hoch_0696	1.336e-39	154.0	28IKZ@1|root,2Z8MJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1702)	-	-	-	ko:K21161	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	DUF1702
DTH1_k127_9462392_7	1265313.HRUBRA_00902	0.0002902	47.0	2EKEB@1|root,33E4I@2|Bacteria,1NI9U@1224|Proteobacteria,1SGHQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9462392_0	886293.Sinac_2212	3.431e-116	379.0	COG3293@1|root,COG3293@2|Bacteria,2IY34@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
DTH1_k127_9462392_5	1340493.JNIF01000003_gene2695	1.913e-07	62.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9462392_3	1227352.C173_18071	1.126e-12	72.0	COG0697@1|root,COG0697@2|Bacteria,1VP2K@1239|Firmicutes,4I1UM@91061|Bacilli,26WQN@186822|Paenibacillaceae	91061|Bacilli	EG	Protein of unknown function (DUF2569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569
DTH1_k127_9462392_4	1303518.CCALI_01840	1.243e-12	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_9462392_2	1403819.BATR01000164_gene5643	1.361e-17	95.0	COG2010@1|root,COG2010@2|Bacteria,46V0R@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
DTH1_k127_9462392_6	1353531.AZNX01000039_gene5954	2.802e-05	56.0	COG1621@1|root,COG2931@1|root,COG1621@2|Bacteria,COG2931@2|Bacteria,1MWTX@1224|Proteobacteria,2U5DU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
DTH1_k127_9468661_0	1210884.HG799465_gene12146	5.389e-106	354.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_9468661_3	1301098.PKB_0417	2.564e-63	221.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
DTH1_k127_9468661_5	478741.JAFS01000001_gene1060	5.615e-27	114.0	COG2026@1|root,COG2026@2|Bacteria,46Z14@74201|Verrucomicrobia,37H0T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9468661_1	497964.CfE428DRAFT_0539	5.094e-96	317.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
DTH1_k127_9468661_4	497964.CfE428DRAFT_2063	1.145e-34	136.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
DTH1_k127_9468661_2	497964.CfE428DRAFT_2062	2.043e-77	273.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH1_k127_9468661_6	903814.ELI_3081	1.987e-18	92.0	COG1408@1|root,COG5652@1|root,COG1408@2|Bacteria,COG5652@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,25X0Z@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH1_k127_9468661_7	886293.Sinac_7299	8.159e-18	93.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2IY17@203682|Planctomycetes	203682|Planctomycetes	S	competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
DTH1_k127_9471494_2	1123070.KB899254_gene1284	1.385e-45	171.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
DTH1_k127_9471494_1	1254432.SCE1572_15425	8.305e-64	227.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,2YWKZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
DTH1_k127_9471494_0	497964.CfE428DRAFT_4177	9.917e-170	545.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH1_k127_9476488_0	1123242.JH636434_gene5621	5.239e-188	599.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
DTH1_k127_9476488_1	452637.Oter_1109	1.2e-47	177.0	COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae	414999|Opitutae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9476488_2	382464.ABSI01000010_gene3520	1.628e-37	157.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42
DTH1_k127_9482182_5	1268635.Loa_00420	4.379e-36	139.0	COG0623@1|root,COG0623@2|Bacteria,1N64Z@1224|Proteobacteria,1T3N8@1236|Gammaproteobacteria,1JC7V@118969|Legionellales	118969|Legionellales	I	KR domain	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH1_k127_9482182_3	344747.PM8797T_12848	4.638e-61	220.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH1_k127_9482182_4	272624.lpg0359	2.637e-41	159.0	COG0236@1|root,COG0236@2|Bacteria,1NM9E@1224|Proteobacteria,1SINP@1236|Gammaproteobacteria,1JEJN@118969|Legionellales	118969|Legionellales	IQ	Phosphopantetheine attachment site	acpP_2	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH1_k127_9482182_6	1122165.AUHS01000023_gene240	7.397e-21	102.0	COG0764@1|root,COG0764@2|Bacteria,1PCKD@1224|Proteobacteria,1SXNH@1236|Gammaproteobacteria,1JDAD@118969|Legionellales	118969|Legionellales	I	FabA-like domain	fabA	-	-	-	-	-	-	-	-	-	-	-	FabA
DTH1_k127_9482182_0	272624.lpg0361	1.873e-142	465.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JDCZ@118969|Legionellales	118969|Legionellales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH1_k127_9482182_1	297246.lpp0427	1.265e-99	344.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JD6F@118969|Legionellales	118969|Legionellales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH1_k127_9482182_2	1122165.AUHS01000023_gene237	1.046e-65	241.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RXSU@1236|Gammaproteobacteria,1JDJP@118969|Legionellales	118969|Legionellales	M	lipid A biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
DTH1_k127_9482182_7	661478.OP10G_1142	7.493e-15	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_9490480_0	886293.Sinac_7042	1.397e-138	451.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
DTH1_k127_9490480_2	639030.JHVA01000001_gene3130	8.659e-13	75.0	2BIJA@1|root,32CS2@2|Bacteria,3Y9DG@57723|Acidobacteria	57723|Acidobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
DTH1_k127_9490480_1	1396141.BATP01000027_gene1185	6.001e-118	390.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH1_k127_9496132_3	886293.Sinac_5304	4.871e-09	61.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
DTH1_k127_9496132_2	497964.CfE428DRAFT_2876	4.447e-90	299.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DTH1_k127_9496132_0	497964.CfE428DRAFT_4132	1.117e-177	568.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_9496132_1	452637.Oter_1003	1.345e-135	443.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
DTH1_k127_9508205_0	886293.Sinac_6968	1.068e-234	746.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
DTH1_k127_9508205_1	886293.Sinac_6967	7.583e-32	126.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH1_k127_9514105_1	1173026.Glo7428_4012	1.258e-50	187.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
DTH1_k127_9514105_0	497964.CfE428DRAFT_2425	1.163e-132	436.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U71@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Laminin_G_3
DTH1_k127_9524976_1	886293.Sinac_7347	1.314e-95	317.0	COG3507@1|root,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9524976_7	552398.HMPREF0866_03064	1.319e-21	98.0	2ED8C@1|root,3374X@2|Bacteria,1W0C5@1239|Firmicutes,24S5N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Smr
DTH1_k127_9524976_5	497964.CfE428DRAFT_0420	2.204e-39	153.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9524976_3	1144275.COCOR_02843	1.291e-50	192.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH1_k127_9524976_4	478741.JAFS01000001_gene2028	3.382e-43	166.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH1_k127_9524976_0	1267535.KB906767_gene1032	1.311e-97	332.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DTH1_k127_9524976_8	1396141.BATP01000057_gene3046	6.21e-05	48.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9524976_2	386456.JQKN01000023_gene72	5.278e-66	231.0	arCOG01778@1|root,arCOG01778@2157|Archaea,2XU6W@28890|Euryarchaeota	28890|Euryarchaeota	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
DTH1_k127_9524976_6	349965.yinte0001_29520	5.078e-36	143.0	COG0697@1|root,COG0697@2|Bacteria,1MVGC@1224|Proteobacteria,1RMXB@1236|Gammaproteobacteria,41EAE@629|Yersinia	1236|Gammaproteobacteria	EG	EamA-like transporter family	yddG	GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	iBWG_1329.BWG_1294,iE2348C_1286.E2348C_1607,iECDH10B_1368.ECDH10B_1604,iECDH1ME8569_1439.ECDH1ME8569_1416,iECS88_1305.ECS88_1565,iEcDH1_1363.EcDH1_2175,iJO1366.b1473,iNRG857_1313.NRG857_07295,iSSON_1240.SSON_1651,iUMN146_1321.UM146_09675	EamA
DTH1_k127_9546734_1	497964.CfE428DRAFT_3906	5.948e-79	266.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH1_k127_9546734_0	1121104.AQXH01000001_gene1195	2.781e-88	301.0	COG1012@1|root,COG1012@2|Bacteria,4NZV1@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DTH1_k127_9546734_2	1205680.CAKO01000002_gene2136	1.756e-34	147.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9569149_3	1192034.CAP_3665	2.856e-44	165.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
DTH1_k127_9569149_4	398767.Glov_2515	2.259e-41	160.0	2DGUS@1|root,32U80@2|Bacteria,1MZK3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9569149_7	443254.Marpi_0296	8.045e-08	56.0	COG1715@1|root,COG2189@1|root,COG1715@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07316,ko:K07448	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,Mrr_N,Mrr_cat,N6_N4_Mtase
DTH1_k127_9569149_5	1499967.BAYZ01000088_gene5060	6.212e-28	120.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
DTH1_k127_9569149_9	935567.JAES01000002_gene626	1.79e-05	51.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9569149_8	670307.HYPDE_29893	1.086e-05	54.0	2FH9D@1|root,3493Q@2|Bacteria,1ND9G@1224|Proteobacteria,2UJ2Y@28211|Alphaproteobacteria,3N997@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
DTH1_k127_9569149_1	686340.Metal_2200	5.634e-54	208.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9569149_6	1232410.KI421421_gene3334	2.011e-11	75.0	2DT2H@1|root,33IDP@2|Bacteria,1NXAG@1224|Proteobacteria,430YG@68525|delta/epsilon subdivisions,2WVZY@28221|Deltaproteobacteria,43VAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
DTH1_k127_9569149_0	243233.MCA1632	6.26e-102	363.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XE6E@135618|Methylococcales	135618|Methylococcales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
DTH1_k127_9569149_2	690850.Desaf_1399	2.7e-51	202.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,43ESD@68525|delta/epsilon subdivisions,2X9MI@28221|Deltaproteobacteria,2MF6N@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
DTH1_k127_9584769_1	1077285.AGDG01000021_gene776	1.148e-35	140.0	COG1520@1|root,COG1520@2|Bacteria,4NM00@976|Bacteroidetes,2FR1A@200643|Bacteroidia,4ANP9@815|Bacteroidaceae	976|Bacteroidetes	S	unsaturated rhamnogalacturonyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,Glyco_hydro_88,PQQ_2
DTH1_k127_9584769_2	1123508.JH636439_gene975	3.09e-13	84.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH1_k127_9584769_0	1235803.C825_03594	3.295e-210	691.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH1_k127_9596377_2	595460.RRSWK_04460	1.643e-95	317.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH1_k127_9596377_6	595460.RRSWK_06357	8.78e-07	60.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PmoA
DTH1_k127_9596377_0	886293.Sinac_5476	1.874e-207	676.0	COG0153@1|root,COG1207@1|root,COG0153@2|Bacteria,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	galK	-	2.3.1.209,2.7.1.157,2.7.1.6	ko:K00849,ko:K02406,ko:K18674,ko:K21379	ko00052,ko00520,ko01100,ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map00052,map00520,map01100,map02020,map02040,map04621,map04626,map05132,map05134	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko02035,ko04147	-	-	-	DUF4954,GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg,Hexapep
DTH1_k127_9596377_1	1288963.ADIS_1775	3.196e-177	567.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9596377_3	428125.CLOLEP_03042	6.894e-81	287.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
DTH1_k127_9596377_5	1219084.AP014508_gene1338	6.819e-15	91.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DTH1_k127_9596377_4	497964.CfE428DRAFT_5353	2.209e-20	109.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH1_k127_9596377_7	1158146.KB907123_gene599	0.0009561	48.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
DTH1_k127_9601934_1	269799.Gmet_1302	8.428e-150	485.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
DTH1_k127_9601934_6	1403819.BATR01000061_gene1887	9.147e-41	162.0	COG0625@1|root,COG0625@2|Bacteria,46SQB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
DTH1_k127_9601934_9	886293.Sinac_6824	6.501e-15	83.0	28WRV@1|root,2ZIRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9601934_8	257313.BP2758	1.427e-19	99.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,3T4GB@506|Alcaligenaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
DTH1_k127_9601934_0	452637.Oter_0618	2.837e-282	882.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH1_k127_9601934_2	497964.CfE428DRAFT_6510	1.987e-135	444.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
DTH1_k127_9601934_5	452637.Oter_1638	6.607e-107	351.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,3K7NZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH1_k127_9601934_4	497964.CfE428DRAFT_6512	1.833e-120	399.0	COG0577@1|root,COG0577@2|Bacteria,46SK8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_9601934_3	497964.CfE428DRAFT_6513	9.188e-134	439.0	COG0577@1|root,COG0577@2|Bacteria,46SPG@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH1_k127_9601934_7	743719.PaelaDRAFT_1262	4.073e-40	151.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,26SVT@186822|Paenibacillaceae	91061|Bacilli	G	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
DTH1_k127_9633836_0	756272.Plabr_1226	4.272e-98	329.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH1_k127_9633836_1	1122212.AULO01000008_gene1383	3.664e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1XI7D@135619|Oceanospirillales	135619|Oceanospirillales	H	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_6,TPR_8
DTH1_k127_9647915_1	886293.Sinac_4672	5.172e-32	131.0	COG1403@1|root,COG1403@2|Bacteria,2J3RR@203682|Planctomycetes	203682|Planctomycetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
DTH1_k127_9647915_0	926549.KI421517_gene2208	5.625e-162	521.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47NGQ@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	3.5.1.32	ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH1_k127_9647915_3	330214.NIDE0329	9.57e-05	46.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_9656200_1	240016.ABIZ01000001_gene5219	7.692e-11	74.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
DTH1_k127_9656200_0	497964.CfE428DRAFT_4611	5.576e-65	240.0	COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DTH1_k127_9670328_5	313606.M23134_07726	1.87e-05	56.0	COG0296@1|root,COG1372@1|root,COG1404@1|root,COG4447@1|root,COG0296@2|Bacteria,COG1372@2|Bacteria,COG1404@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
DTH1_k127_9670328_3	452637.Oter_3887	8.443e-18	84.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,46WP0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	oxidoreductase	-	-	1.5.5.1	ko:K00311,ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
DTH1_k127_9670328_2	794903.OPIT5_30315	1.445e-21	101.0	COG5499@1|root,COG5499@2|Bacteria	2|Bacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
DTH1_k127_9670328_4	794903.OPIT5_30320	5.488e-17	84.0	COG4680@1|root,COG4680@2|Bacteria	2|Bacteria	K	protein conserved in bacteria	higB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1903311,GO:2000112,GO:2000113	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
DTH1_k127_9670328_1	452637.Oter_3887	1.697e-295	921.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,46WP0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	oxidoreductase	-	-	1.5.5.1	ko:K00311,ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
DTH1_k127_9670328_0	452637.Oter_4534	0.0	1823.0	COG0458@1|root,COG0458@2|Bacteria,46UZV@74201|Verrucomicrobia,3K7MQ@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH1_k127_967653_1	240016.ABIZ01000001_gene5818	3.094e-49	182.0	COG3852@1|root,COG3852@2|Bacteria,46Z4V@74201|Verrucomicrobia,2ITPC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
DTH1_k127_967653_0	497964.CfE428DRAFT_5035	1.006e-210	666.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DTH1_k127_9681122_2	1089550.ATTH01000002_gene84	1.4e-13	75.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DTH1_k127_9681122_0	1122169.AREN01000009_gene642	4.541e-97	331.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,1JFTD@118969|Legionellales	118969|Legionellales	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
DTH1_k127_9681122_1	1305735.JAFT01000005_gene2369	1.552e-18	93.0	COG1396@1|root,COG1396@2|Bacteria,1N8D1@1224|Proteobacteria,2U832@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
DTH1_k127_9696065_1	1122917.KB899665_gene3972	7e-116	383.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,26W35@186822|Paenibacillaceae	91061|Bacilli	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH1_k127_9696065_0	452637.Oter_1374	2.533e-173	550.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
DTH1_k127_9702651_4	494419.ALPM01000029_gene3144	8.957e-13	71.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,1W7IB@1268|Micrococcaceae	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DTH1_k127_9702651_1	1396418.BATQ01000166_gene1881	1.081e-46	173.0	COG0299@1|root,COG0615@1|root,COG0299@2|Bacteria,COG0615@2|Bacteria,46SUW@74201|Verrucomicrobia,2IWN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FIM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,Formyl_trans_N
DTH1_k127_9702651_3	1499967.BAYZ01000119_gene3208	3.794e-20	103.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH1_k127_9702651_0	497964.CfE428DRAFT_5970	7.93e-258	807.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia	74201|Verrucomicrobia	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DTH1_k127_9702651_5	1230476.C207_05423	4.499e-09	61.0	COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,2TRXW@28211|Alphaproteobacteria,3JW83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
DTH1_k127_9702651_2	5722.XP_001582588.1	6.979e-25	115.0	COG0666@1|root,KOG4177@2759|Eukaryota	5722.XP_001582588.1|-	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9714532_5	1121957.ATVL01000014_gene1459	1.048e-75	273.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9714532_4	1313304.CALK_1499	3.641e-98	332.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0043877,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576	3.1.1.31,3.5.99.6	ko:K01057,ko:K02080,ko:K02564	ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035,R08365	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979,iYO844.BSU02360,iYO844.BSU35020,iZ_1308.Z0825	Glucosamine_iso,PIG-L
DTH1_k127_9714532_7	1266908.AQPB01000038_gene531	1.742e-08	63.0	COG3428@1|root,COG3428@2|Bacteria,1N3Z5@1224|Proteobacteria,1SAN2@1236|Gammaproteobacteria,1WYRT@135613|Chromatiales	135613|Chromatiales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
DTH1_k127_9714532_3	1313304.CALK_1498	1.363e-107	360.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH1_k127_9714532_0	1313304.CALK_1497	9.02e-140	455.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH1_k127_9714532_1	179408.Osc7112_2512	2.456e-135	438.0	COG0714@1|root,COG0714@2|Bacteria,1G0WS@1117|Cyanobacteria,1H9JV@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH1_k127_9714532_2	56107.Cylst_0588	6.831e-118	394.0	COG1721@1|root,COG1721@2|Bacteria,1G1ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH1_k127_9714532_6	756067.MicvaDRAFT_0417	1.442e-46	183.0	COG1305@1|root,COG1305@2|Bacteria,1G1YY@1117|Cyanobacteria,1HA69@1150|Oscillatoriales	1117|Cyanobacteria	E	SMART Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH1_k127_972051_0	382464.ABSI01000013_gene1549	2.774e-57	227.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH1_k127_972051_3	1191523.MROS_0975	0.0003116	54.0	COG3211@1|root,COG4935@1|root,COG3211@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
DTH1_k127_972051_1	1396141.BATP01000022_gene383	1.769e-49	195.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
DTH1_k127_9724541_6	497964.CfE428DRAFT_1718	1.131e-17	83.0	COG3558@1|root,COG3558@2|Bacteria,46VBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
DTH1_k127_9724541_1	497964.CfE428DRAFT_3635	6.666e-141	471.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
DTH1_k127_9724541_3	55529.EKX47288	6.482e-101	348.0	COG0144@1|root,KOG1122@2759|Eukaryota	2759|Eukaryota	J	rRNA (cytosine-C5-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
DTH1_k127_9724541_7	382464.ABSI01000007_gene4120	1.931e-12	74.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia,2IURV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9724541_2	28072.Nos7524_0364	1.308e-102	339.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
DTH1_k127_9724541_5	1396418.BATQ01000046_gene6162	6.017e-32	133.0	COG0742@1|root,COG0742@2|Bacteria,46T62@74201|Verrucomicrobia,2IUEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
DTH1_k127_9724541_0	1403819.BATR01000178_gene5964	4.308e-143	464.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_9724541_4	497964.CfE428DRAFT_5017	1.599e-67	251.0	COG1354@1|root,COG1354@2|Bacteria,46UBD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpA
DTH1_k127_9729499_0	1210884.HG799469_gene14219	1.946e-141	475.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH1_k127_9739231_2	240016.ABIZ01000001_gene1124	3.638e-34	131.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH1_k127_9739231_3	886293.Sinac_3116	9.049e-12	75.0	COG2165@1|root,COG2165@2|Bacteria,2IZ6K@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH1_k127_9739231_1	1396418.BATQ01000026_gene5273	5.327e-82	277.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,46TBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19
DTH1_k127_9739231_0	497964.CfE428DRAFT_4081	3.376e-108	366.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH1_k127_9744260_2	497964.CfE428DRAFT_3301	2.775e-44	161.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
DTH1_k127_9744260_1	13035.Dacsa_2950	3.545e-122	398.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,RE_Eco29kI
DTH1_k127_9744260_0	1430440.MGMSRv2_3763	1.044e-203	646.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QVE4@1224|Proteobacteria,2TUH9@28211|Alphaproteobacteria,2JW67@204441|Rhodospirillales	204441|Rhodospirillales	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
DTH1_k127_9762681_0	497964.CfE428DRAFT_3010	3.785e-162	523.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH1_k127_9762681_1	497964.CfE428DRAFT_5350	2.27e-79	275.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH1_k127_9765425_1	264732.Moth_2023	2.08e-66	243.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,DUF4380
DTH1_k127_9765425_2	794903.OPIT5_11625	3.013e-61	220.0	COG1451@1|root,COG1451@2|Bacteria,46VW6@74201|Verrucomicrobia,3K7I9@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
DTH1_k127_9765425_4	296591.Bpro_2383	2.626e-12	75.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VXVS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH1_k127_9765425_3	395961.Cyan7425_0454	6.303e-13	70.0	COG3153@1|root,COG3153@2|Bacteria,1GK4X@1117|Cyanobacteria,3KIFY@43988|Cyanothece	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
DTH1_k127_9765425_0	497964.CfE428DRAFT_4754	9.853e-72	247.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
DTH1_k127_9769648_6	1198114.AciX9_2572	1.778e-26	112.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria,2JJPA@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
DTH1_k127_9769648_5	202955.BBND01000021_gene2914	8.98e-50	186.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria,3NSZ4@468|Moraxellaceae	1236|Gammaproteobacteria	L	Group II intron, maturase-specific domain	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
DTH1_k127_9769648_7	411902.CLOBOL_03557	5.396e-24	106.0	COG2721@1|root,COG2721@2|Bacteria,1TUD7@1239|Firmicutes,24R3M@186801|Clostridia,221BF@1506553|Lachnoclostridium	186801|Clostridia	G	SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	SAF
DTH1_k127_9769648_0	1123269.NX02_17320	1.186e-191	606.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2K15R@204457|Sphingomonadales	204457|Sphingomonadales	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
DTH1_k127_9769648_2	1123242.JH636434_gene4153	3.926e-152	491.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH1_k127_9769648_3	1403819.BATR01000135_gene4812	5.242e-115	380.0	COG0329@1|root,COG0329@2|Bacteria,46UU4@74201|Verrucomicrobia	74201|Verrucomicrobia	EM	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH1_k127_9769648_8	1142394.PSMK_06110	1.096e-12	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_9769648_4	583355.Caka_0956	4.969e-92	319.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
DTH1_k127_9769648_1	380358.XALC_0037	5.134e-158	512.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,1RP70@1236|Gammaproteobacteria,1X56Y@135614|Xanthomonadales	135614|Xanthomonadales	G	Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
DTH1_k127_9776129_0	497964.CfE428DRAFT_3537	1.926e-112	372.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DTH1_k127_9776129_1	452637.Oter_3094	2.563e-81	295.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,46U96@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_4,SpoIIE
DTH1_k127_9776129_2	247490.KSU1_B0180	1.436e-14	77.0	COG2841@1|root,COG2841@2|Bacteria,2J45A@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
DTH1_k127_9784239_3	547042.BACCOPRO_00511	5.639e-35	149.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,2FR8R@200643|Bacteroidia,4AQA2@815|Bacteroidaceae	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH1_k127_9784239_0	344747.PM8797T_32395	2.699e-113	387.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
DTH1_k127_9784239_5	886293.Sinac_4894	1.038e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_9784239_4	886293.Sinac_4894	3.187e-33	142.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_9784239_6	886293.Sinac_4894	1.987e-20	108.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH1_k127_9784239_1	497964.CfE428DRAFT_2981	3.467e-104	371.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1648,DUF4019,Pkinase
DTH1_k127_9784239_2	1267535.KB906767_gene3433	6.398e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,3Y8YQ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9797892_0	710696.Intca_1127	2.143e-18	97.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
DTH1_k127_9797892_1	313628.LNTAR_04871	0.0004512	44.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_9798983_2	1524467.IV04_18570	2.654e-50	189.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,1RQ0C@1236|Gammaproteobacteria,3ZZIA@613|Serratia	1236|Gammaproteobacteria	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	GO:0000287,GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0071704,GO:1901575	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF1260.b0757,iAPECO1_1312.APECO1_1331,iBWG_1329.BWG_0609,iEC55989_1330.EC55989_0736,iECABU_c1320.ECABU_c07960,iECB_1328.ECB_00710,iECDH1ME8569_1439.ECDH1ME8569_0710,iECH74115_1262.ECH74115_0860,iECIAI1_1343.ECIAI1_0725,iECNA114_1301.ECNA114_0687,iECO103_1326.ECO103_0745,iECOK1_1307.ECOK1_0757,iECP_1309.ECP_0768,iECS88_1305.ECS88_0773,iECSE_1348.ECSE_0810,iECSF_1327.ECSF_0683,iECSP_1301.ECSP_0810,iECW_1372.ECW_m0812,iECs_1301.ECs0785,iEKO11_1354.EKO11_3129,iETEC_1333.ETEC_0761,iEcDH1_1363.EcDH1_2885,iEcE24377_1341.EcE24377A_0784,iEcolC_1368.EcolC_2905,iG2583_1286.G2583_0923,iJO1366.b0757,iJR904.b0757,iLF82_1304.LF82_0794,iNRG857_1313.NRG857_03350,iUMN146_1321.UM146_13870,iUMNK88_1353.UMNK88_796,iUTI89_1310.UTI89_C0754,iWFL_1372.ECW_m0812,iY75_1357.Y75_RS03945,ic_1306.c0833	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
DTH1_k127_9798983_5	426716.JOAJ01000004_gene3022	4.708e-24	104.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4G30U@85025|Nocardiaceae	201174|Actinobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DTH1_k127_9798983_6	1048339.KB913029_gene1929	5.082e-20	100.0	2E37T@1|root,32Y7G@2|Bacteria,2HKTZ@201174|Actinobacteria,4EWSP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
DTH1_k127_9798983_7	452637.Oter_0732	5.936e-10	68.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
DTH1_k127_9798983_10	1303518.CCALI_02493	1.508e-06	59.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_9798983_9	1869.MB27_39975	2.704e-07	62.0	2EGCD@1|root,33A46@2|Bacteria,2HUKV@201174|Actinobacteria,4DFF1@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
DTH1_k127_9798983_1	497964.CfE428DRAFT_2629	4.424e-77	271.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
DTH1_k127_9798983_0	204669.Acid345_4092	1.861e-82	286.0	COG0009@1|root,COG0009@2|Bacteria,3Y3VW@57723|Acidobacteria,2JHTT@204432|Acidobacteriia	204432|Acidobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
DTH1_k127_9798983_3	452637.Oter_0025	8.232e-45	181.0	COG1538@1|root,COG1538@2|Bacteria,46VZS@74201|Verrucomicrobia,3K7CV@414999|Opitutae	414999|Opitutae	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH1_k127_9798983_4	944479.JQLX01000016_gene325	3.049e-28	119.0	COG2050@1|root,COG2050@2|Bacteria,1N8F8@1224|Proteobacteria,42V78@68525|delta/epsilon subdivisions,2WRBA@28221|Deltaproteobacteria,2M7BC@213113|Desulfurellales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH1_k127_9798983_8	596152.DesU5LDRAFT_3550	2.036e-09	61.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria,1R42U@1224|Proteobacteria,42UMM@68525|delta/epsilon subdivisions,2WQVW@28221|Deltaproteobacteria,2MANV@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
DTH1_k127_9816745_2	1123242.JH636434_gene5057	2.141e-52	188.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9816745_0	272123.Anacy_2354	6.358e-143	467.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,1HIFU@1161|Nostocales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH1_k127_9816745_5	661478.OP10G_0968	3.806e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH1_k127_9816745_3	452637.Oter_2787	8.672e-51	193.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH1_k127_9816745_4	452637.Oter_0650	2.492e-25	121.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9816745_1	1480694.DC28_14620	5.028e-110	366.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH1_k127_9841856_0	452637.Oter_2454	1.319e-250	784.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
DTH1_k127_9841856_1	530564.Psta_0956	9.932e-70	247.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH1_k127_9841856_3	1123242.JH636434_gene4823	1.766e-07	56.0	COG2133@1|root,COG2133@2|Bacteria,2IWVG@203682|Planctomycetes	203682|Planctomycetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9841856_2	1121456.ATVA01000012_gene2541	7.469e-11	64.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria,2MBAU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
DTH1_k127_9875011_3	694440.JOMF01000004_gene1346	4.691e-46	178.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota,2N9E7@224756|Methanomicrobia	224756|Methanomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_9875011_0	1123354.AUDR01000001_gene2019	4.093e-145	468.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KTB7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
DTH1_k127_9875011_2	1123354.AUDR01000001_gene2018	5.804e-83	286.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,1KRK3@119069|Hydrogenophilales	1224|Proteobacteria	M	Glycosyl transferase family 2	arnC	GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH1_k127_9875011_1	56780.SYN_02389	1.751e-115	383.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH1_k127_9875648_6	180332.JTGN01000003_gene1959	6.193e-06	57.0	COG0407@1|root,COG0407@2|Bacteria,1VJHK@1239|Firmicutes,24TV3@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH1_k127_9875648_1	1487923.DP73_21435	6.507e-34	145.0	COG0407@1|root,COG0407@2|Bacteria,1VPBU@1239|Firmicutes,24IYJ@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH1_k127_9875648_0	314230.DSM3645_24165	6.571e-192	610.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH1_k127_9875648_4	926569.ANT_30650	1.647e-30	123.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
DTH1_k127_9875648_2	1121440.AUMA01000016_gene183	7.1e-33	129.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WP7R@28221|Deltaproteobacteria,2MDD2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
DTH1_k127_9875648_3	1121904.ARBP01000010_gene2339	1.347e-32	127.0	COG3369@1|root,COG3369@2|Bacteria,4NW9E@976|Bacteroidetes,47W0Y@768503|Cytophagia	976|Bacteroidetes	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
DTH1_k127_9875648_5	1121472.AQWN01000006_gene1701	1.89e-25	117.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25ZZS@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
DTH1_k127_9879675_0	344747.PM8797T_20643	5.798e-143	475.0	COG1520@1|root,COG1520@2|Bacteria,2IX2Z@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH1_k127_9879675_3	595460.RRSWK_05296	2.955e-16	93.0	COG1012@1|root,COG1012@2|Bacteria,2IZ2G@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH1_k127_9879675_1	497964.CfE428DRAFT_4839	3.394e-82	286.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH1_k127_9879675_2	452637.Oter_1107	4.458e-57	207.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
DTH1_k127_9886411_3	240016.ABIZ01000001_gene5947	1.079e-49	178.0	COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia,2ITXS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH1_k127_9886411_1	1122947.FR7_4282	1.637e-157	511.0	COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4H38R@909932|Negativicutes	909932|Negativicutes	G	Major Facilitator	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
DTH1_k127_9886411_0	1210884.HG799463_gene9560	1.141e-176	568.0	COG0578@1|root,COG0578@2|Bacteria,2IX2V@203682|Planctomycetes	203682|Planctomycetes	C	Glycerol-3-phosphate dehydrogenase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
DTH1_k127_9886411_2	679935.Alfi_2300	1.476e-103	344.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,2FRNM@200643|Bacteroidia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
DTH1_k127_9899181_4	497964.CfE428DRAFT_0566	1.237e-33	130.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
DTH1_k127_9899181_5	871585.BDGL_001653	3.698e-05	55.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1S5BT@1236|Gammaproteobacteria,3NK23@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
DTH1_k127_9899181_2	1337936.IJ00_09705	1.488e-115	388.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1HKZ8@1161|Nostocales	1117|Cyanobacteria	EGP	major facilitator superfamily MFS_1	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
DTH1_k127_9899181_3	1396418.BATQ01000133_gene4024	2.217e-109	362.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
DTH1_k127_9899181_1	497964.CfE428DRAFT_5147	8.343e-122	411.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH1_k127_9899181_0	497964.CfE428DRAFT_5146	5.186e-133	433.0	COG1541@1|root,COG1541@2|Bacteria,46UTU@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
DTH1_k127_9903351_3	583355.Caka_1995	6.981e-98	339.0	COG0472@1|root,COG0472@2|Bacteria,46SNJ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
DTH1_k127_9903351_7	497964.CfE428DRAFT_3096	4.437e-43	164.0	COG0250@1|root,COG0250@2|Bacteria,46SYX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
DTH1_k127_9903351_1	497964.CfE428DRAFT_2775	1.942e-149	498.0	COG0489@1|root,COG0489@2|Bacteria,46UJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
DTH1_k127_9903351_6	497964.CfE428DRAFT_2774	1.276e-49	186.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
DTH1_k127_9903351_5	497964.CfE428DRAFT_2773	1.128e-53	205.0	2F6K4@1|root,33Z30@2|Bacteria,46VYC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
DTH1_k127_9903351_13	1121373.KB903654_gene1652	5.125e-05	57.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	ydcK	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CBM_35,NTP_transf_3,PEP_mutase
DTH1_k127_9903351_8	869213.JCM21142_72843	3.442e-24	120.0	COG1404@1|root,COG3210@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125,ko:K21449	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536,ko02000	1.B.40.2	-	-	5_nucleotid_C,CW_binding_2,Fil_haemagg,Haemagg_act,He_PIG,HemolysinCabind,LTD,Metallophos,PATR
DTH1_k127_9903351_2	1123399.AQVE01000001_gene684	9.973e-112	397.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
DTH1_k127_9903351_9	278957.ABEA03000004_gene4536	1.7e-17	92.0	COG2165@1|root,COG2165@2|Bacteria,46YQC@74201|Verrucomicrobia,3K9ZW@414999|Opitutae	414999|Opitutae	U	N-terminal cleavage protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH1_k127_9903351_11	378806.STAUR_0706	5.978e-10	71.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X7B6@28221|Deltaproteobacteria,2YUAZ@29|Myxococcales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
DTH1_k127_9903351_12	706587.Desti_1174	1.581e-06	60.0	COG2204@1|root,COG2204@2|Bacteria,1RKC4@1224|Proteobacteria,42SJ3@68525|delta/epsilon subdivisions,2WPI1@28221|Deltaproteobacteria,2MRU7@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH1_k127_9903351_10	335543.Sfum_0069	6.835e-14	84.0	COG1357@1|root,COG2201@1|root,COG1357@2|Bacteria,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K18876	ko02020,ko02030,ko04626,map02020,map02030,map04626	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,DDE_5,Response_reg,TAL_effector
DTH1_k127_9903351_0	240016.ABIZ01000001_gene5946	1.505e-174	559.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia,2IWJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_9903351_4	497964.CfE428DRAFT_0981	1.485e-54	194.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
DTH1_k127_9941650_0	583355.Caka_3109	2.179e-194	642.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
DTH1_k127_9953367_9	1192034.CAP_1634	2.081e-08	63.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
DTH1_k127_9953367_8	452637.Oter_3848	2.995e-14	76.0	2EPKD@1|root,33H70@2|Bacteria,46WC0@74201|Verrucomicrobia,3K89T@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9953367_3	886293.Sinac_0152	2.432e-100	332.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH1_k127_9953367_6	1123371.ATXH01000009_gene1101	6.226e-69	242.0	COG1912@1|root,COG1912@2|Bacteria,2GHAQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
DTH1_k127_9953367_7	237368.SCABRO_03960	4.605e-67	236.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH1_k127_9953367_4	452637.Oter_1130	1.596e-98	333.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,3K8ZD@414999|Opitutae	414999|Opitutae	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
DTH1_k127_9953367_1	518766.Rmar_2586	9.675e-130	424.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
DTH1_k127_9953367_5	136993.KB900626_gene2135	1.226e-94	318.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2V487@28211|Alphaproteobacteria,36ZQF@31993|Methylocystaceae	28211|Alphaproteobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DTH1_k127_9953367_2	518766.Rmar_2589	1.2e-100	340.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
DTH1_k127_9953367_0	518766.Rmar_2590	1.28e-173	555.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
DTH1_k127_9953367_10	395963.Bind_0508	4.649e-05	48.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,2UIK4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	HycI
DTH1_k127_9963556_0	497964.CfE428DRAFT_3486	0.0	1310.0	COG1038@1|root,COG1038@2|Bacteria,46S8N@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Conserved carboxylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
DTH1_k127_9963556_7	671143.DAMO_1226	1.836e-23	105.0	COG0314@1|root,COG0314@2|Bacteria,2NR4E@2323|unclassified Bacteria	2|Bacteria	H	MoaE protein	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
DTH1_k127_9963556_9	383372.Rcas_2923	1.428e-12	70.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,376I2@32061|Chloroflexia	32061|Chloroflexia	H	PFAM molybdopterin biosynthesis MoaE protein	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
DTH1_k127_9963556_5	1297617.JPJD01000047_gene1362	1.187e-51	195.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DTH1_k127_9963556_2	452637.Oter_0935	2.637e-153	494.0	COG0042@1|root,COG0042@2|Bacteria,46TCT@74201|Verrucomicrobia,3K895@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
DTH1_k127_9963556_8	1173026.Glo7428_2961	2.483e-16	91.0	COG3240@1|root,COG3240@2|Bacteria,1FZV1@1117|Cyanobacteria	1117|Cyanobacteria	I	Phospholipase lecithinase hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
DTH1_k127_9963556_3	497964.CfE428DRAFT_5469	3.677e-78	278.0	COG2067@1|root,COG2067@2|Bacteria,46SR3@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
DTH1_k127_9963556_1	452637.Oter_1792	1.684e-174	562.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH1_k127_9963556_4	204669.Acid345_2517	3.497e-72	252.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
DTH1_k127_9963556_6	1122917.KB899659_gene5085	2.843e-35	141.0	2E9V0@1|root,3340V@2|Bacteria,1VBMU@1239|Firmicutes,4IRRQ@91061|Bacilli,26ZN3@186822|Paenibacillaceae	91061|Bacilli	I	carotenoid biosynthetic process	-	-	-	ko:K10212	ko00906,map00906	-	R07656	RC00041	ko00000,ko00001,ko01000	-	-	-	-
DTH1_k127_9970488_0	1396418.BATQ01000059_gene2065	8.383e-56	198.0	COG3391@1|root,COG3391@2|Bacteria,46SD8@74201|Verrucomicrobia,2IVKU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH1_k127_9988166_7	583355.Caka_1736	1.822e-23	108.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH1_k127_9988166_6	273068.TTE1388	1.41e-26	110.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DTH1_k127_9988166_0	497964.CfE428DRAFT_3556	3.817e-286	895.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DTH1_k127_9988166_1	497964.CfE428DRAFT_3344	3.227e-224	722.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
DTH1_k127_9988166_2	1051632.TPY_0699	1.023e-223	707.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WCEY@538999|Clostridiales incertae sedis	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH1_k127_9988166_5	1156937.MFUM_300024	3.094e-46	184.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia,37FWK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH1_k127_9988166_3	404589.Anae109_0139	5.142e-132	436.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
DTH1_k127_9988166_4	349741.Amuc_2115	9.688e-124	406.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,2ITV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Seryl-tRNA synthetase N-terminal domain	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DTH1_k127_9996254_0	497964.CfE428DRAFT_1688	4.431e-112	381.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
## 4094 queries scanned
## Total time (seconds): 18.601410388946533
## Rate: 220.09 q/s