## Wed Nov 13 12:22:56 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/DTH2_bin.33.fa -m mmseqs --itype genome -o DTH2_bin.33 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/DTH2_bin.33 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DTH2_k127_10071976_15	760192.Halhy_0958	1.654e-47	175.0	29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
DTH2_k127_10071976_17	929556.Solca_2089	1.24e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_10071976_23	435591.BDI_1190	4.35e-10	66.0	2E8SV@1|root,3333M@2|Bacteria,4NSHV@976|Bacteroidetes,2FV1F@200643|Bacteroidia,22YEX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
DTH2_k127_10071976_12	1408433.JHXV01000010_gene527	2.777e-58	228.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4PPWM@976|Bacteroidetes,1IKWE@117743|Flavobacteriia,2PBIK@246874|Cryomorphaceae	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
DTH2_k127_10071976_16	445970.ALIPUT_00376	9.937e-46	177.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,2FMHT@200643|Bacteroidia,22U0W@171550|Rikenellaceae	976|Bacteroidetes	M	Lysin motif	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
DTH2_k127_10071976_10	515635.Dtur_0501	3.419e-99	339.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Cu_amine_oxidN1,DLH,DUF3887,Hydrolase_4,Peptidase_S9
DTH2_k127_10071976_4	706587.Desti_4506	7.957e-216	689.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N,ECH_1
DTH2_k127_10071976_2	1125863.JAFN01000001_gene1223	4.354e-230	733.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
DTH2_k127_10071976_0	316055.RPE_3216	2.885e-254	794.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,3JRW4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
DTH2_k127_10071976_13	1244869.H261_12176	3.655e-54	192.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria,2JSX2@204441|Rhodospirillales	204441|Rhodospirillales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
DTH2_k127_10071976_6	76114.ebA2055	4.573e-125	410.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,2KVJQ@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_10071976_20	1156844.KB891798_gene6242	1.131e-24	118.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
DTH2_k127_10071976_9	931627.MycrhDRAFT_2786	8.167e-105	353.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,237CP@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_10071976_18	2423.NA23_0209080	3.075e-33	132.0	COG2185@1|root,COG2185@2|Bacteria,2GD2V@200918|Thermotogae	200918|Thermotogae	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
DTH2_k127_10071976_3	1244869.H261_14175	5.067e-225	709.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	-	-	-	-	-	-	-	-	-	-	ArgK,B12-binding,MM_CoA_mutase
DTH2_k127_10071976_8	76114.ebA2066	1.935e-117	390.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
DTH2_k127_10071976_7	1125863.JAFN01000001_gene1239	1.184e-119	424.0	COG0493@1|root,COG4231@1|root,COG0493@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WKYE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-2	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
DTH2_k127_10071976_21	96561.Dole_0441	5.71e-23	106.0	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MJ4W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
DTH2_k127_10071976_14	457570.Nther_2152	1.39e-47	176.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia	186801|Clostridia	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	1.17.1.5,1.2.5.3	ko:K03518,ko:K20446	ko00760,ko01120,map00760,map01120	-	R01720,R11168	RC00589,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
DTH2_k127_10071976_1	1244869.H261_12196	1.25e-244	777.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JZI6@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DTH2_k127_10071976_19	177437.HRM2_37990	5.057e-33	139.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42R7J@68525|delta/epsilon subdivisions,2WMT4@28221|Deltaproteobacteria,2MKWI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
DTH2_k127_10071976_11	667014.Thein_2149	2.158e-64	232.0	COG0079@1|root,COG0079@2|Bacteria,2GGZI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_10071976_5	1406840.Q763_12565	1.887e-215	680.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1HY99@117743|Flavobacteriia,2NSKX@237|Flavobacterium	976|Bacteroidetes	E	Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_10071976_22	926549.KI421517_gene1118	7.401e-15	79.0	2APBA@1|root,31EDH@2|Bacteria,4NSFA@976|Bacteroidetes,47SNA@768503|Cytophagia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
DTH2_k127_1121181_1	1341155.FSS13T_02180	4.959e-69	237.0	COG1670@1|root,COG1670@2|Bacteria,4NMB7@976|Bacteroidetes,1I271@117743|Flavobacteriia,2P04V@237|Flavobacterium	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_1121181_0	1434325.AZQN01000003_gene2852	2.04e-223	697.0	COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,47P29@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH2_k127_1121181_2	1121875.KB907549_gene1905	1.44e-58	205.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
DTH2_k127_1121181_4	709797.CSIRO_4112	2.121e-07	61.0	COG0500@1|root,COG0500@2|Bacteria,1NM6Y@1224|Proteobacteria,2UR09@28211|Alphaproteobacteria,3K31N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DTH2_k127_1121181_3	1454007.JAUG01000045_gene3804	1.032e-57	208.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,1IPTU@117747|Sphingobacteriia	976|Bacteroidetes	S	MOSC domain containing protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
DTH2_k127_1129005_10	1408473.JHXO01000004_gene133	4.342e-05	49.0	2EQMK@1|root,33I7I@2|Bacteria,4NY3R@976|Bacteroidetes,2FVUP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1129005_4	1270196.JCKI01000003_gene1920	8.906e-115	383.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_1129005_7	1408433.JHXV01000008_gene221	2.424e-50	200.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1129005_8	1313301.AUGC01000001_gene1425	2.619e-45	171.0	COG0669@1|root,COG4339@1|root,COG0669@2|Bacteria,COG4339@2|Bacteria,4NM84@976|Bacteroidetes	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH2_k127_1129005_6	1120951.AUBG01000005_gene2202	8.277e-52	187.0	COG0614@1|root,COG0614@2|Bacteria,4NQYJ@976|Bacteroidetes,1I43J@117743|Flavobacteriia	976|Bacteroidetes	P	GxxExxY protein	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_1129005_1	1454007.JAUG01000022_gene1251	9.784e-176	559.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_1129005_3	755732.Fluta_0387	1.093e-142	458.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia,2PABG@246874|Cryomorphaceae	976|Bacteroidetes	S	FMN-dependent dehydrogenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
DTH2_k127_1129005_5	1408433.JHXV01000029_gene3118	4.564e-65	233.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_1129005_2	468059.AUHA01000002_gene691	1.398e-156	504.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
DTH2_k127_1129005_0	468059.AUHA01000002_gene690	3.445e-223	702.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
DTH2_k127_1129005_9	468059.AUHA01000002_gene689	3.361e-38	147.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ITMH@117747|Sphingobacteriia	976|Bacteroidetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DTH2_k127_113330_25	984262.SGRA_2537	1.991e-47	186.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_113330_31	1197477.IA57_12700	9.178e-07	61.0	COG3291@1|root,COG3291@2|Bacteria,4NH8H@976|Bacteroidetes,1HYV1@117743|Flavobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	sprC	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_113330_26	485917.Phep_4082	1.324e-44	164.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,1ISVI@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH2_k127_113330_17	1034807.FBFL15_0631	1.913e-94	312.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia,2NSHX@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH2_k127_113330_23	153721.MYP_738	1.057e-48	179.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,47PAN@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH2_k127_113330_5	992406.RIA_1525	4.372e-208	652.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DTH2_k127_113330_21	929713.NIASO_11650	6.47e-64	224.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1IS1Q@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
DTH2_k127_113330_3	1270196.JCKI01000001_gene3976	3.096e-224	701.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
DTH2_k127_113330_10	929556.Solca_3734	8.724e-159	506.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
DTH2_k127_113330_12	1121373.KB903623_gene2358	2.897e-139	450.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47K9J@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH2_k127_113330_19	755732.Fluta_1965	1.228e-77	264.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
DTH2_k127_113330_24	1227739.Hsw_0533	6.345e-48	177.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,47PS7@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH2_k127_113330_28	926549.KI421517_gene1957	7.608e-33	130.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,47QG0@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH2_k127_113330_2	468059.AUHA01000002_gene1094	3.698e-240	757.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
DTH2_k127_113330_11	1270196.JCKI01000001_gene3983	1.163e-151	494.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
DTH2_k127_113330_13	929556.Solca_3727	2.936e-128	424.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH2_k127_113330_29	1107311.Q767_11915	1.831e-29	129.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,4NHRP@976|Bacteroidetes,1HXVY@117743|Flavobacteriia,2NV2U@237|Flavobacterium	976|Bacteroidetes	MN	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_113330_27	1150600.ADIARSV_2690	2.934e-40	162.0	COG1835@1|root,COG1835@2|Bacteria,4NIR9@976|Bacteroidetes,1J081@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_113330_0	1131812.JQMS01000001_gene40	4.633e-319	996.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DTH2_k127_113330_4	938709.AUSH02000073_gene1679	1.03e-212	666.0	COG1914@1|root,COG1914@2|Bacteria,4NDZ1@976|Bacteroidetes	976|Bacteroidetes	P	COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
DTH2_k127_113330_6	762903.Pedsa_3478	3.639e-205	655.0	COG1032@1|root,COG1032@2|Bacteria,4NJAN@976|Bacteroidetes	976|Bacteroidetes	C	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH2_k127_113330_7	153721.MYP_3853	1.614e-195	626.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH2_k127_113330_30	153721.MYP_3835	4.328e-28	119.0	2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_10
DTH2_k127_113330_22	755732.Fluta_1545	1.63e-52	189.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1I24B@117743|Flavobacteriia,2PAUP@246874|Cryomorphaceae	976|Bacteroidetes	G	sugar-phosphate isomerases, RpiB LacA LacB family	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
DTH2_k127_113330_9	700598.Niako_6341	3.126e-160	509.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
DTH2_k127_113330_14	926562.Oweho_2308	9.756e-110	375.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBM8@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_113330_20	1408433.JHXV01000015_gene1713	4.451e-66	258.0	COG3920@1|root,COG3920@2|Bacteria,4NM3G@976|Bacteroidetes,1I0XX@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS_9
DTH2_k127_113330_15	755732.Fluta_1546	4.588e-101	334.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia,2PAUQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH2_k127_113330_18	1121904.ARBP01000006_gene3735	3.167e-86	303.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	ompA	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	CHU_C,OMP_b-brl,OmpA,PKD,TSP_3
DTH2_k127_113330_1	1121104.AQXH01000004_gene15	1.156e-242	766.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1INTV@117747|Sphingobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
DTH2_k127_113330_16	929703.KE386491_gene2923	1.569e-96	324.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_113330_8	1237149.C900_04979	7.793e-178	566.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_1265119_11	1250278.JQNQ01000001_gene3168	3.043e-96	327.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1HY8U@117743|Flavobacteriia	976|Bacteroidetes	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH2_k127_1265119_5	1313421.JHBV01000019_gene5306	6.389e-156	521.0	COG0308@1|root,COG0308@2|Bacteria,4P1D6@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH2_k127_1265119_14	1408433.JHXV01000038_gene2216	5.401e-72	262.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2PBI8@246874|Cryomorphaceae	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1265119_12	1408433.JHXV01000038_gene2216	2.451e-90	316.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2PBI8@246874|Cryomorphaceae	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1265119_6	755732.Fluta_1029	6.806e-151	482.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,1IMQF@117743|Flavobacteriia,2PBAU@246874|Cryomorphaceae	976|Bacteroidetes	GM	GDP-mannose 4,6 dehydratase	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
DTH2_k127_1265119_2	926549.KI421517_gene654	2.394e-187	602.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,47K61@768503|Cytophagia	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_1265119_8	153721.MYP_3446	5.805e-140	453.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
DTH2_k127_1265119_0	641526.ADIWIN_3894	1.222e-205	653.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH2_k127_1265119_10	153721.MYP_4250	5.694e-99	328.0	COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,47N90@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	fabG3	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_1265119_1	1408433.JHXV01000011_gene2025	2.934e-189	597.0	COG0304@1|root,COG0304@2|Bacteria,4NFBN@976|Bacteroidetes,1HXQ3@117743|Flavobacteriia,2PAHI@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_1265119_15	1408433.JHXV01000011_gene2024	5.428e-31	123.0	COG0236@1|root,COG0236@2|Bacteria,4NV57@976|Bacteroidetes,1I568@117743|Flavobacteriia,2PB5Z@246874|Cryomorphaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP_2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_1265119_13	929713.NIASO_13540	3e-74	260.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,1IT2S@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
DTH2_k127_1265119_3	118163.Ple7327_2936	3.946e-178	571.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,3VIVK@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
DTH2_k127_1265119_4	1173264.KI913949_gene2380	1.465e-171	550.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1H8G7@1150|Oscillatoriales	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
DTH2_k127_1265119_7	1453500.AT05_01825	1.891e-145	487.0	COG3291@1|root,COG3291@2|Bacteria,4NICC@976|Bacteroidetes	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_1265119_9	1408433.JHXV01000004_gene3388	3.001e-122	417.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_130664_11	1121898.Q766_03505	1.699e-06	55.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia,2NUTP@237|Flavobacterium	976|Bacteroidetes	O	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_130664_7	997352.HMPREF9419_0570	3.633e-65	234.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,2FMGJ@200643|Bacteroidia	976|Bacteroidetes	I	lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_130664_6	2340.JV46_25570	7.5e-82	298.0	2DVT6@1|root,33X2K@2|Bacteria,1NWQT@1224|Proteobacteria,1SQDW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_130664_5	1408433.JHXV01000017_gene1618	1.678e-84	306.0	2DQUH@1|root,338RF@2|Bacteria,4P2QJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_130664_9	1408433.JHXV01000017_gene1617	5.441e-51	195.0	2F61I@1|root,33YJY@2|Bacteria,4P4C0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_130664_2	1408433.JHXV01000017_gene1616	1.883e-118	398.0	COG2199@1|root,COG3706@2|Bacteria,4PPWN@976|Bacteroidetes	976|Bacteroidetes	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_130664_1	1408433.JHXV01000017_gene1615	4.271e-165	530.0	COG1215@1|root,COG1215@2|Bacteria,4PIA1@976|Bacteroidetes,1IFXS@117743|Flavobacteriia,2PC4R@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
DTH2_k127_130664_8	1408473.JHXO01000011_gene3070	1.659e-64	229.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,2FXYF@200643|Bacteroidia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH2_k127_130664_0	929556.Solca_1315	2.478e-190	600.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_130664_10	1408473.JHXO01000010_gene3763	1.238e-48	199.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
DTH2_k127_130664_4	1408473.JHXO01000001_gene2298	7.131e-85	285.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DTH2_k127_130664_3	929556.Solca_0238	1.939e-101	333.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,1IPHX@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
DTH2_k127_1314789_1	153721.MYP_2223	8.225e-192	613.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,47KKH@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH2_k127_1314789_6	929713.NIASO_00115	1.765e-102	340.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
DTH2_k127_1314789_15	1408445.JHXP01000006_gene126	6.547e-48	183.0	COG1247@1|root,COG1247@2|Bacteria,1PZ4K@1224|Proteobacteria,1T7VF@1236|Gammaproteobacteria,1JFWU@118969|Legionellales	118969|Legionellales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
DTH2_k127_1314789_18	1469557.JSWF01000031_gene2005	2.433e-32	138.0	COG0726@1|root,COG0726@2|Bacteria,4NN39@976|Bacteroidetes,1I52I@117743|Flavobacteriia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_1314789_25	1237149.C900_03971	1.17e-05	57.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_1314789_22	313598.MED152_09815	5.073e-07	61.0	COG2356@1|root,COG3291@1|root,COG2356@2|Bacteria,COG3291@2|Bacteria,4PMBH@976|Bacteroidetes,1IMSY@117743|Flavobacteriia,3VXB4@52959|Polaribacter	976|Bacteroidetes	L	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1314789_17	1410653.JHVC01000005_gene2567	4.836e-40	162.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia,36WDK@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
DTH2_k127_1314789_14	395493.BegalDRAFT_0509	2.345e-59	213.0	COG0438@1|root,COG0438@2|Bacteria,1RJ7A@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1314789_20	866775.HMPREF9243_1674	1.373e-14	87.0	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes,4HEKF@91061|Bacilli	91061|Bacilli	S	Polysaccharide biosynthesis protein	cps2J	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_1314789_4	929556.Solca_2881	2.02e-119	402.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1IP68@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
DTH2_k127_1314789_10	1408473.JHXO01000010_gene3654	6.264e-86	289.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
DTH2_k127_1314789_11	153721.MYP_3101	1.419e-85	302.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4P298@976|Bacteroidetes,47TIX@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_1314789_19	1243664.CAVL020000006_gene4938	1.362e-22	101.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,1ZHW0@1386|Bacillus	91061|Bacilli	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
DTH2_k127_1314789_7	1122605.KB893643_gene791	1.702e-94	319.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1INVP@117747|Sphingobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_1314789_9	929556.Solca_3378	2.393e-91	310.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
DTH2_k127_1314789_13	1028805.GGC_0583	2.856e-68	237.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1YABV@135625|Pasteurellales	135625|Pasteurellales	M	Bacterial sugar transferase	-	-	2.7.8.40	ko:K21303	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf
DTH2_k127_1314789_2	1124780.ANNU01000005_gene2425	7.377e-161	515.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_1314789_21	555500.I215_06752	4.456e-12	70.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1I41M@117743|Flavobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
DTH2_k127_1314789_0	1408473.JHXO01000009_gene3365	3.22e-228	717.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia	976|Bacteroidetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DTH2_k127_1314789_8	1107311.Q767_01615	3.089e-92	325.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
DTH2_k127_1314789_5	269798.CHU_1683	1.194e-117	387.0	COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,47NHC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH2_k127_1314789_23	314231.FP2506_18724	2.346e-06	54.0	2EESX@1|root,338KG@2|Bacteria,1RD32@1224|Proteobacteria,2U7BH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3307)	MA20_18760	-	-	-	-	-	-	-	-	-	-	-	DUF3307
DTH2_k127_1314789_3	755732.Fluta_0965	3.861e-148	475.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia,2PA62@246874|Cryomorphaceae	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
DTH2_k127_1314789_16	926549.KI421517_gene2253	1.92e-43	168.0	COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,47Q6P@768503|Cytophagia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH2_k127_1314789_12	402777.KB235903_gene2615	6.67e-78	274.0	COG2203@1|root,COG3829@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG3920@2|Bacteria,1GPXH@1117|Cyanobacteria,1HHTQ@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	ETR1	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_3,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9
DTH2_k127_133226_8	755732.Fluta_0625	3.711e-181	574.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1HY08@117743|Flavobacteriia,2PBFC@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_133226_28	1313421.JHBV01000016_gene5584	2.999e-67	241.0	COG1609@1|root,COG1609@2|Bacteria,4NESN@976|Bacteroidetes,1IQUP@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4
DTH2_k127_133226_29	525373.HMPREF0766_12776	7.547e-60	214.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1IS5M@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
DTH2_k127_133226_25	1122621.ATZA01000037_gene3529	3.725e-81	279.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,1INUG@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_133226_32	1453498.LG45_00520	8.363e-42	159.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia,2NTX5@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
DTH2_k127_133226_21	1454007.JAUG01000061_gene460	1.488e-112	370.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1INNA@117747|Sphingobacteriia	976|Bacteroidetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
DTH2_k127_133226_37	700598.Niako_7317	1.245e-20	97.0	2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,1ITPF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_133226_4	929556.Solca_2743	9.696e-197	635.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH2_k127_133226_3	468059.AUHA01000004_gene2172	1.193e-204	646.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_133226_7	926562.Oweho_2827	1.364e-186	591.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia,2PAGT@246874|Cryomorphaceae	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
DTH2_k127_133226_5	762903.Pedsa_0132	2.65e-191	606.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH2_k127_133226_23	929713.NIASO_19585	9.962e-108	361.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DTH2_k127_133226_15	929556.Solca_2738	2.206e-135	440.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1IPF4@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DTH2_k127_133226_14	762903.Pedsa_0135	3.12e-144	471.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_133226_31	762903.Pedsa_0136	1.029e-43	169.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
DTH2_k127_133226_11	468059.AUHA01000004_gene2179	9.054e-168	538.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1IQJQ@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DTH2_k127_133226_13	1408433.JHXV01000032_gene1131	1.008e-153	501.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DTH2_k127_133226_34	1123234.AUKI01000013_gene1652	7.452e-37	143.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1I1X6@117743|Flavobacteriia	976|Bacteroidetes	S	YqeY-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
DTH2_k127_133226_39	1189612.A33Q_0853	9.541e-15	81.0	2AFVR@1|root,315YE@2|Bacteria,4PK8B@976|Bacteroidetes,47SSJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_133226_43	1348114.OM33_02790	0.0002986	49.0	COG3650@1|root,COG3650@2|Bacteria,1N019@1224|Proteobacteria,1SBAD@1236|Gammaproteobacteria,2Q4FW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Membrane-bound lysozyme-inhibitor of c-type lysozyme	-	-	-	ko:K08985	-	-	-	-	ko00000	-	-	-	MliC,YscW
DTH2_k127_133226_10	485917.Phep_0873	8.63e-176	554.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1IR3A@117747|Sphingobacteriia	976|Bacteroidetes	G	Transketolase	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_133226_20	926562.Oweho_1341	3.56e-117	392.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
DTH2_k127_133226_16	1123234.AUKI01000011_gene1431	4.771e-135	434.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia	976|Bacteroidetes	G	Transketolase	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DTH2_k127_133226_9	1122621.ATZA01000072_gene2331	4.659e-180	569.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DTH2_k127_133226_36	105559.Nwat_0046	3.483e-30	123.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1X28T@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_133226_17	531844.FIC_01275	9.472e-132	423.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1HWN1@117743|Flavobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
DTH2_k127_133226_41	1453498.LG45_11885	0.000127	52.0	2F276@1|root,30YX5@2|Bacteria,4PCWH@976|Bacteroidetes,1IDE6@117743|Flavobacteriia,2NY4C@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_133226_1	1121889.AUDM01000013_gene1806	1.459e-297	922.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia,2NTTJ@237|Flavobacterium	976|Bacteroidetes	L	DNA Topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_133226_0	1121899.Q764_00460	0.0	1074.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2NUEE@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH2_k127_133226_6	694427.Palpr_2235	2.135e-187	607.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,2FMV1@200643|Bacteroidia,22WQI@171551|Porphyromonadaceae	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
DTH2_k127_133226_42	1250005.PHEL85_1582	0.0002723	55.0	COG3291@1|root,COG3291@2|Bacteria,4NUFV@976|Bacteroidetes,1HZH1@117743|Flavobacteriia,3VWV6@52959|Polaribacter	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_133226_35	643867.Ftrac_0904	7.873e-34	153.0	COG2911@1|root,COG2911@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
DTH2_k127_133226_38	585502.HMPREF0645_1800	5.986e-20	92.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,2G2C9@200643|Bacteroidia	976|Bacteroidetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH2_k127_133226_33	1249975.JQLP01000005_gene2318	1.004e-41	157.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1I2YH@117743|Flavobacteriia,2P6U2@244698|Gillisia	976|Bacteroidetes	J	Endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_133226_26	929562.Emtol_0855	1.621e-77	265.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,47MH4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH2_k127_133226_24	1121896.JMLU01000006_gene40	2.902e-106	350.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia,2NT5U@237|Flavobacterium	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
DTH2_k127_133226_19	883096.HMPREF9699_01848	4.085e-122	404.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
DTH2_k127_133226_27	1408433.JHXV01000001_gene784	2.527e-67	243.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,1I7GW@117743|Flavobacteriia,2PAW4@246874|Cryomorphaceae	976|Bacteroidetes	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
DTH2_k127_133226_2	929556.Solca_1191	1.635e-226	720.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
DTH2_k127_133226_22	880071.Fleli_3161	2.94e-109	363.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_133226_12	929556.Solca_4142	8.766e-157	510.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1IQVW@117747|Sphingobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_133226_18	468059.AUHA01000002_gene1366	3.447e-122	406.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1IRGW@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
DTH2_k127_133226_30	1042376.AFPK01000031_gene870	1.122e-59	214.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia,406A0@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_1338465_0	111105.HR09_02510	3.537e-110	377.0	COG2957@1|root,COG2957@2|Bacteria,4NJ5R@976|Bacteroidetes,2FV2Z@200643|Bacteroidia,22YYS@171551|Porphyromonadaceae	976|Bacteroidetes	E	Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37	ko:K08589	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_1338465_2	742817.HMPREF9449_02796	1.708e-41	160.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,2FSA6@200643|Bacteroidia,22ZRD@171551|Porphyromonadaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_1338465_1	1313301.AUGC01000004_gene2420	5.117e-109	357.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
DTH2_k127_1338465_4	1408813.AYMG01000039_gene2341	8.987e-27	124.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPAI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_1338465_3	700598.Niako_3251	7.107e-29	124.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_138301_1	1313301.AUGC01000003_gene2099	2.653e-141	452.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the KdsA family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
DTH2_k127_138301_6	545693.BMQ_3114	8.958e-33	136.0	COG2755@1|root,COG2755@2|Bacteria,1V1B9@1239|Firmicutes,4IQ6G@91061|Bacilli,1ZRHN@1386|Bacillus	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH2_k127_138301_4	383381.EH30_11370	7.331e-48	184.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,2K2Y2@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_138301_5	1408433.JHXV01000004_gene3448	1.426e-43	167.0	COG0421@1|root,COG0421@2|Bacteria,4NPK5@976|Bacteroidetes,1I2D9@117743|Flavobacteriia,2PBSW@246874|Cryomorphaceae	976|Bacteroidetes	E	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
DTH2_k127_138301_3	643867.Ftrac_2976	6.655e-86	290.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DTH2_k127_138301_2	153721.MYP_38	9.08e-111	367.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,47K45@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
DTH2_k127_138301_0	1349822.NSB1T_01680	4.916e-157	504.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,22VY5@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_138301_9	755732.Fluta_0614	6.799e-13	79.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DTH2_k127_138301_8	1392490.JHZX01000001_gene1409	1.098e-14	83.0	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_138301_7	1453498.LG45_10275	6.155e-24	111.0	2CCJ7@1|root,2ZA02@2|Bacteria,4NGH8@976|Bacteroidetes,1HXKM@117743|Flavobacteriia,2NVPK@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1428572_3	1121896.JMLU01000003_gene2072	0.0004973	50.0	2DHKH@1|root,3004R@2|Bacteria,4PGYE@976|Bacteroidetes,1INC1@117743|Flavobacteriia,2NYZV@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1428572_0	547042.BACCOPRO_02695	1.125e-72	254.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,4ANA5@815|Bacteroidaceae	976|Bacteroidetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH2_k127_1428572_1	468059.AUHA01000008_gene2762	3.506e-44	162.0	COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,1IRFX@117747|Sphingobacteriia	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH2_k127_1458200_0	929556.Solca_2733	1.637e-186	591.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1IQY7@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_1458200_2	743722.Sph21_3549	5.926e-67	239.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH2_k127_1458200_1	1002367.HMPREF0673_01761	8.824e-111	364.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,2FPJM@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DTH2_k127_1458200_3	926562.Oweho_1468	7.431e-40	149.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia,2PB1G@246874|Cryomorphaceae	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
DTH2_k127_1458200_4	700598.Niako_3251	8.04e-34	137.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_148386_1	388413.ALPR1_05330	2.327e-109	360.0	COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia	976|Bacteroidetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
DTH2_k127_148386_3	1086011.HJ01_00420	1.629e-66	232.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,1I22T@117743|Flavobacteriia,2NSXP@237|Flavobacterium	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DTH2_k127_148386_2	714943.Mucpa_4494	2.215e-72	256.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
DTH2_k127_148386_0	743722.Sph21_0075	2.491e-155	496.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DTH2_k127_1502625_3	1094466.KQS_09855	3.453e-05	46.0	COG2827@1|root,COG2827@2|Bacteria,4NUKY@976|Bacteroidetes,1II52@117743|Flavobacteriia,2NXVP@237|Flavobacterium	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_1502625_2	1122176.KB903531_gene2762	3.739e-31	137.0	COG1572@1|root,COG4447@1|root,COG1572@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Laminin_G_3,TM_helix
DTH2_k127_1502625_1	1185876.BN8_04601	1.534e-52	191.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,47PZ9@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
DTH2_k127_1502625_0	1121481.AUAS01000002_gene3278	1.326e-164	527.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,47JIH@768503|Cytophagia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DTH2_k127_1541551_3	869213.JCM21142_190	3.024e-15	84.0	29UMW@1|root,30FZE@2|Bacteria,4PP6C@976|Bacteroidetes,47YH7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1541551_2	1123277.KB893173_gene1890	1.027e-49	181.0	COG3832@1|root,COG3832@2|Bacteria,4NT4P@976|Bacteroidetes,47R8X@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DTH2_k127_1541551_1	1346330.M472_13410	5.795e-169	535.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1IR3Y@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
DTH2_k127_1541551_0	153721.MYP_924	9.22e-252	810.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
DTH2_k127_155372_0	1286632.P278_32990	6.091e-214	681.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,1HWY2@117743|Flavobacteriia	976|Bacteroidetes	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
DTH2_k127_155372_2	1267211.KI669560_gene1823	1.512e-177	564.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1IRNQ@117747|Sphingobacteriia	976|Bacteroidetes	F	Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
DTH2_k127_155372_27	880071.Fleli_3246	1.443e-09	68.0	2EBH5@1|root,335HP@2|Bacteria,4NW0F@976|Bacteroidetes,47VF8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_155372_20	1305737.JAFX01000001_gene3507	1.141e-38	145.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
DTH2_k127_155372_19	746697.Aeqsu_0327	3.624e-42	170.0	28JIH@1|root,2Z9BT@2|Bacteria,4NIF7@976|Bacteroidetes,1HYCU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
DTH2_k127_155372_7	1121904.ARBP01000001_gene5644	1.348e-133	454.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,47MVB@768503|Cytophagia	976|Bacteroidetes	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
DTH2_k127_155372_18	1121904.ARBP01000009_gene4229	1.087e-51	193.0	COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,47WA7@768503|Cytophagia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_155372_26	1203550.HMPREF1475_00724	1.447e-10	73.0	COG4085@1|root,COG4085@2|Bacteria,4NW36@976|Bacteroidetes,2FRXA@200643|Bacteroidia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
DTH2_k127_155372_22	984262.SGRA_2947	2.747e-27	126.0	COG2374@1|root,COG4085@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria,4NIB0@976|Bacteroidetes,1ITET@117747|Sphingobacteriia	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,LTD
DTH2_k127_155372_1	760192.Halhy_5161	8.122e-186	610.0	COG1629@1|root,COG1629@2|Bacteria,4NFW1@976|Bacteroidetes,1IQ77@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_155372_10	927658.AJUM01000044_gene656	1.935e-106	355.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,2FNH4@200643|Bacteroidia,3XINX@558415|Marinilabiliaceae	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_155372_25	1246.JMEA01000003_gene1032	1.828e-19	104.0	COG4886@1|root,COG4886@2|Bacteria,1V3UH@1239|Firmicutes,4HM8K@91061|Bacilli,4AYGC@81850|Leuconostocaceae	91061|Bacilli	S	Leucine-rich repeats, outliers	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	LRR_4,SMI1_KNR4
DTH2_k127_155372_17	153721.MYP_168	1.262e-70	269.0	2DBC9@1|root,2Z8CA@2|Bacteria,4NJS4@976|Bacteroidetes,47QAH@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
DTH2_k127_155372_6	743722.Sph21_2274	1.179e-137	447.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DTH2_k127_155372_3	926549.KI421517_gene3857	3.826e-174	550.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,47J9X@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_155372_12	755732.Fluta_0840	3.293e-94	315.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia,2PAQ1@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DTH2_k127_155372_8	700598.Niako_4140	5.878e-108	359.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DTH2_k127_155372_15	468059.AUHA01000003_gene1914	4.317e-77	263.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1IRH8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
DTH2_k127_155372_21	869213.JCM21142_31186	5.044e-36	144.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia	976|Bacteroidetes	S	PFAM PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
DTH2_k127_155372_16	1313421.JHBV01000043_gene3029	2.458e-72	269.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_155372_5	709991.Odosp_1635	4.29e-147	473.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,2FMD1@200643|Bacteroidia,22W4T@171551|Porphyromonadaceae	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_155372_13	929556.Solca_3902	2.501e-90	301.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1INZC@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DTH2_k127_155372_4	1121481.AUAS01000011_gene5150	1.377e-150	485.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,47U25@768503|Cytophagia	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
DTH2_k127_155372_23	376686.Fjoh_0254	6.893e-27	113.0	COG2827@1|root,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,1I2RZ@117743|Flavobacteriia,2NXN4@237|Flavobacterium	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_155372_14	714943.Mucpa_4331	1.868e-77	265.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,1IRTC@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
DTH2_k127_155372_9	926549.KI421517_gene2167	3.528e-107	361.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,47M1S@768503|Cytophagia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DTH2_k127_155372_11	1469557.JSWF01000018_gene54	5.892e-99	329.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
DTH2_k127_155372_24	755732.Fluta_3229	1.316e-22	104.0	COG3386@1|root,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IN8T@117743|Flavobacteriia,2PBT6@246874|Cryomorphaceae	976|Bacteroidetes	G	SPTR Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
DTH2_k127_1567096_3	1267211.KI669560_gene738	3.046e-30	121.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1IV58@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
DTH2_k127_1567096_1	468059.AUHA01000003_gene1959	6.751e-135	436.0	COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,1IQBU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_1567096_0	445970.ALIPUT_00182	3.925e-226	708.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_1567096_4	743722.Sph21_0328	4.726e-18	84.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DTH2_k127_1567096_2	313595.P700755_001318	4.891e-99	337.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,4C2WF@83612|Psychroflexus	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DTH2_k127_1624104_4	575615.HMPREF0670_02676	6.323e-34	143.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,2FNG9@200643|Bacteroidia	976|Bacteroidetes	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_1624104_5	1122986.KB908334_gene1849	7.229e-19	91.0	COG0810@1|root,COG0810@2|Bacteria,4P6JR@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
DTH2_k127_1624104_3	755732.Fluta_1111	1.416e-91	321.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IIYJ@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
DTH2_k127_1624104_0	485918.Cpin_1418	4.621e-215	698.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1INM2@117747|Sphingobacteriia	976|Bacteroidetes	CE	PFAM Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
DTH2_k127_1624104_2	643867.Ftrac_2856	3.505e-138	448.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,47MTQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
DTH2_k127_1624104_1	643867.Ftrac_3705	1.075e-202	636.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_1643087_11	153721.MYP_1941	5.379e-83	280.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47KCT@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH2_k127_1643087_22	1122621.ATZA01000004_gene1191	4.353e-27	114.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,1ISBI@117747|Sphingobacteriia	976|Bacteroidetes	J	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
DTH2_k127_1643087_10	1408433.JHXV01000007_gene2959	1.738e-86	295.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1HY0R@117743|Flavobacteriia,2PAPG@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DTH2_k127_1643087_1	1270196.JCKI01000008_gene1468	0.0	1034.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
DTH2_k127_1643087_20	1168034.FH5T_04010	2.536e-48	179.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,2FNA8@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DTH2_k127_1643087_0	926562.Oweho_1913	0.0	1877.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
DTH2_k127_1643087_18	1121007.AUML01000004_gene2429	1.784e-56	199.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia,2YJF8@290174|Aquimarina	976|Bacteroidetes	E	Glycine cleavage H-protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DTH2_k127_1643087_25	742766.HMPREF9455_00095	2.456e-10	66.0	COG5652@1|root,COG5652@2|Bacteria,4NUU6@976|Bacteroidetes,2FUQP@200643|Bacteroidia,231ER@171551|Porphyromonadaceae	976|Bacteroidetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1643087_9	1211813.CAPH01000012_gene329	1.591e-87	295.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,2FNVR@200643|Bacteroidia,22U8J@171550|Rikenellaceae	976|Bacteroidetes	Q	Permease MlaE	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH2_k127_1643087_7	385682.AFSL01000014_gene2721	6.796e-100	331.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,2FM5W@200643|Bacteroidia,3XJCG@558415|Marinilabiliaceae	976|Bacteroidetes	Q	ATPases associated with a variety of cellular activities	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH2_k127_1643087_17	1218108.KB908293_gene1326	1.108e-57	205.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1HZQ3@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DTH2_k127_1643087_23	762903.Pedsa_2475	1.601e-22	100.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU1T@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
DTH2_k127_1643087_19	485917.Phep_0696	3.816e-53	196.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,1ISMP@117747|Sphingobacteriia	976|Bacteroidetes	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
DTH2_k127_1643087_16	760192.Halhy_2411	5.467e-61	225.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1IRFW@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
DTH2_k127_1643087_14	865938.Weevi_2011	4.043e-64	224.0	COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,1HY16@117743|Flavobacteriia	976|Bacteroidetes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
DTH2_k127_1643087_12	1408433.JHXV01000027_gene3728	8.424e-79	275.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_1643087_21	926562.Oweho_3286	3.726e-40	154.0	COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1I48G@117743|Flavobacteriia	976|Bacteroidetes	J	2',5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
DTH2_k127_1643087_5	760192.Halhy_6309	4.458e-151	506.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_1643087_6	1270196.JCKI01000009_gene3248	1.867e-116	385.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
DTH2_k127_1643087_8	435590.BVU_1829	6.873e-97	329.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,2FPCQ@200643|Bacteroidia,4AMUD@815|Bacteroidaceae	976|Bacteroidetes	L	COG2812 DNA polymerase III gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
DTH2_k127_1643087_15	926549.KI421517_gene3311	1.922e-61	232.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_1643087_24	929556.Solca_2229	1.169e-13	81.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,YceI
DTH2_k127_1643087_2	468059.AUHA01000002_gene679	5.13e-199	629.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
DTH2_k127_1643087_13	755732.Fluta_0618	2.708e-73	260.0	COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes,1ICP7@117743|Flavobacteriia,2PBGK@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
DTH2_k127_1643087_4	153721.MYP_192	8.506e-185	586.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DTH2_k127_1643087_3	926549.KI421517_gene3971	5.393e-195	617.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
DTH2_k127_16638_4	926562.Oweho_1716	1.166e-79	276.0	28PY8@1|root,2ZCHZ@2|Bacteria,4NMGG@976|Bacteroidetes,1I1JV@117743|Flavobacteriia,2PBVU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_16638_7	1168289.AJKI01000002_gene2424	6.558e-18	88.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,2G265@200643|Bacteroidia,3XK2K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_16638_5	755732.Fluta_1284	2.703e-67	259.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_16638_1	1453505.JASY01000021_gene22	3.515e-240	751.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,1HWUA@117743|Flavobacteriia,2NSZA@237|Flavobacterium	976|Bacteroidetes	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_16638_6	1313421.JHBV01000014_gene3924	1.102e-59	220.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_4,Big_5,DUF3494,Exo_endo_phos,LTD,SLH
DTH2_k127_16638_0	1313421.JHBV01000037_gene2910	9.597e-277	859.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes	976|Bacteroidetes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
DTH2_k127_16638_3	1492737.FEM08_32030	9.051e-90	304.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,1I19N@117743|Flavobacteriia,2NXF5@237|Flavobacterium	976|Bacteroidetes	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DTH2_k127_16638_2	1492737.FEM08_32040	3.877e-102	337.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1HYZ9@117743|Flavobacteriia,2NT0S@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
DTH2_k127_1689768_0	869213.JCM21142_83275	8.789e-131	460.0	COG1345@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_1689768_6	926562.Oweho_1422	6.956e-17	96.0	COG3291@1|root,COG3291@2|Bacteria,4PHXB@976|Bacteroidetes,1IBNK@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_1689768_3	1121285.AUFK01000019_gene201	1.187e-23	115.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA
DTH2_k127_1689768_4	1237149.C900_03337	9.446e-22	102.0	295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,47W1I@768503|Cytophagia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1689768_1	1267211.KI669560_gene2807	1.268e-42	157.0	COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,1IZ1N@117747|Sphingobacteriia	976|Bacteroidetes	K	Winged helix DNA-binding domain	marR	-	-	-	-	-	-	-	-	-	-	-	HTH_34
DTH2_k127_1689768_2	700598.Niako_6910	2.155e-26	110.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
DTH2_k127_1689768_5	765911.Thivi_0981	9.368e-21	94.0	COG0428@1|root,COG0664@1|root,COG0428@2|Bacteria,COG0664@2|Bacteria,1QE6Q@1224|Proteobacteria,1S080@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	cNMP_binding
DTH2_k127_1691218_4	1408433.JHXV01000015_gene1768	1.368e-14	78.0	2A94C@1|root,30Y8F@2|Bacteria,4PBZT@976|Bacteroidetes,1ICRM@117743|Flavobacteriia,2PBWN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1691218_2	643867.Ftrac_3304	7.119e-57	207.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
DTH2_k127_1691218_3	385682.AFSL01000105_gene133	1.722e-43	161.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,2FTF6@200643|Bacteroidia,3XK3G@558415|Marinilabiliaceae	976|Bacteroidetes	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
DTH2_k127_1691218_0	926562.Oweho_0762	1.226e-91	324.0	COG1983@1|root,COG3256@1|root,COG1983@2|Bacteria,COG3256@2|Bacteria,4NG3T@976|Bacteroidetes,1HX01@117743|Flavobacteriia,2PAXN@246874|Cryomorphaceae	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
DTH2_k127_1691218_1	927658.AJUM01000043_gene771	1.832e-60	213.0	COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,2G1HP@200643|Bacteroidia,3XKV6@558415|Marinilabiliaceae	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH2_k127_1691218_5	1296415.JACC01000053_gene3651	5.736e-05	46.0	COG1044@1|root,COG3420@1|root,COG1044@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
DTH2_k127_1754381_1	1453498.LG45_11450	1.391e-40	156.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia,2NS7W@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH2_k127_1754381_0	1408473.JHXO01000001_gene2403	2.024e-102	347.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,2FNY8@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
DTH2_k127_1754381_2	1123035.ARLA01000028_gene2469	7.034e-06	51.0	COG1470@1|root,COG4935@1|root,COG1470@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,4C2CH@83612|Psychroflexus	976|Bacteroidetes	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5
DTH2_k127_1791872_5	1453500.AT05_08795	1.368e-65	246.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1791872_11	1107311.Q767_03190	2.477e-08	67.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4PPGS@976|Bacteroidetes,1IKMG@117743|Flavobacteriia,2NWNN@237|Flavobacterium	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH2_k127_1791872_10	694427.Palpr_1114	8.091e-20	106.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,2FV1K@200643|Bacteroidia,22Z9F@171551|Porphyromonadaceae	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,YceI
DTH2_k127_1791872_6	1408433.JHXV01000022_gene3142	3.826e-65	252.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1791872_4	580332.Slit_1984	1.438e-88	296.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
DTH2_k127_1791872_7	485918.Cpin_3332	3.206e-41	157.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,1IYUY@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
DTH2_k127_1791872_8	1185876.BN8_04369	1.015e-25	111.0	2DCP9@1|root,2ZEU1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1791872_1	1406840.Q763_15170	3.965e-140	449.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,2NSN5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
DTH2_k127_1791872_2	929556.Solca_0019	2.917e-99	332.0	COG1741@1|root,COG1741@2|Bacteria,4NN4X@976|Bacteroidetes,1J089@117747|Sphingobacteriia	976|Bacteroidetes	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
DTH2_k127_1791872_9	1121875.KB907556_gene590	8.991e-23	99.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,1I5MP@117743|Flavobacteriia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
DTH2_k127_1791872_3	700598.Niako_5688	3.18e-93	311.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IR6P@117747|Sphingobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_1791872_0	929713.NIASO_11060	5.418e-178	565.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
DTH2_k127_184767_12	1408433.JHXV01000010_gene528	1.076e-37	146.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1I1YF@117743|Flavobacteriia,2PB2E@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DTH2_k127_184767_7	1454007.JAUG01000016_gene1758	1.256e-54	193.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH2_k127_184767_0	1408473.JHXO01000010_gene3748	1.51e-205	668.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH2_k127_184767_4	755732.Fluta_0823	1.371e-71	250.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia,2PAVX@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
DTH2_k127_184767_2	1121859.KB890739_gene2596	4.554e-132	434.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia	976|Bacteroidetes	S	CinA-like protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DTH2_k127_184767_1	929556.Solca_1376	7.635e-143	458.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1IP70@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DTH2_k127_184767_5	694427.Palpr_1792	4.091e-57	207.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,22Y0T@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
DTH2_k127_184767_9	755732.Fluta_2398	3.363e-51	194.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_184767_11	1408433.JHXV01000014_gene3694	4.421e-41	176.0	COG3291@1|root,COG3291@2|Bacteria,4PI05@976|Bacteroidetes,1ICSF@117743|Flavobacteriia,2PBZU@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_184767_6	755732.Fluta_0036	2.272e-56	209.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,1HZ6D@117743|Flavobacteriia,2PBE5@246874|Cryomorphaceae	976|Bacteroidetes	M	Lysin motif	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
DTH2_k127_184767_3	1237149.C900_01166	1.379e-75	262.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DTH2_k127_184767_8	385682.AFSL01000008_gene2611	5.642e-54	195.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,3XJUY@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
DTH2_k127_184767_13	1336803.PHEL49_0200	9.158e-19	96.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1I2IR@117743|Flavobacteriia,3VX24@52959|Polaribacter	976|Bacteroidetes	T	Universal stress protein family	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
DTH2_k127_184767_10	504472.Slin_5735	1.564e-45	175.0	28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,47R7X@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1874101_4	525257.HMPREF0204_11082	1.803e-16	85.0	COG2244@1|root,COG2244@2|Bacteria,4NRKF@976|Bacteroidetes,1I3V4@117743|Flavobacteriia,3ZR5J@59732|Chryseobacterium	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_1874101_3	714943.Mucpa_4219	1.436e-16	82.0	2E372@1|root,32Y6U@2|Bacteria,4NUUI@976|Bacteroidetes,1IU59@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
DTH2_k127_1874101_0	1492737.FEM08_01810	3.052e-148	478.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia,2NSRJ@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH2_k127_1874101_1	929556.Solca_2299	2.949e-115	377.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia	976|Bacteroidetes	E	Hydroxymethylglutaryl-CoA lyase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
DTH2_k127_1874101_2	1121957.ATVL01000006_gene3301	7.317e-18	93.0	2DX8D@1|root,343UE@2|Bacteria,4P6Q1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2023546_7	926562.Oweho_3448	8.682e-25	113.0	28JFU@1|root,30YB4@2|Bacteria,4PC31@976|Bacteroidetes,1ICTS@117743|Flavobacteriia,2PC4T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2023546_1	926562.Oweho_3447	4.83e-87	299.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia	2|Bacteria	C	cytochrome C peroxidase	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
DTH2_k127_2023546_0	1492737.FEM08_07580	9.988e-123	402.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1HWK6@117743|Flavobacteriia,2NSYC@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
DTH2_k127_2023546_4	929556.Solca_1983	5.759e-38	152.0	COG0664@1|root,COG0664@2|Bacteria,4NJR1@976|Bacteroidetes,1IQRM@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_2023546_5	1121007.AUML01000014_gene2859	2.943e-35	143.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia,2YJ8H@290174|Aquimarina	976|Bacteroidetes	D	Domain of Unknown function (DUF542)	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
DTH2_k127_2023546_3	760192.Halhy_6370	7.74e-44	165.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH2_k127_2023546_8	387092.NIS_0202	0.000185	46.0	COG3787@1|root,COG3787@2|Bacteria,1RH76@1224|Proteobacteria,42TS4@68525|delta/epsilon subdivisions,2YPWQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	cofactor binding	Cj1449c	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
DTH2_k127_2307117_15	926556.Echvi_0758	6.978e-06	48.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,47K6T@768503|Cytophagia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
DTH2_k127_2307117_16	991.IW20_23695	1.727e-05	54.0	2ABZA@1|root,311GS@2|Bacteria,4PGAD@976|Bacteroidetes,1IDRU@117743|Flavobacteriia,2NZ20@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2307117_1	1107311.Q767_08970	2.39e-214	676.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2NSUV@237|Flavobacterium	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH2_k127_2307117_9	1408813.AYMG01000028_gene2445	5.166e-91	303.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DTH2_k127_2307117_14	694427.Palpr_2186	2.764e-27	111.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,2FTU6@200643|Bacteroidia,22YS5@171551|Porphyromonadaceae	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DTH2_k127_2307117_12	926549.KI421517_gene1618	5.258e-49	184.0	2DBUB@1|root,2ZB53@2|Bacteria,4NMWS@976|Bacteroidetes,47P3Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2307117_8	755732.Fluta_3176	6.152e-99	334.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia,2PBCS@246874|Cryomorphaceae	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
DTH2_k127_2307117_13	1408433.JHXV01000001_gene1011	9.489e-46	183.0	COG0526@1|root,COG0526@2|Bacteria,4NNSW@976|Bacteroidetes,1ICQA@117743|Flavobacteriia,2PBPX@246874|Cryomorphaceae	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
DTH2_k127_2307117_5	1150600.ADIARSV_3474	1.007e-113	380.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1IRVC@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2307117_10	468059.AUHA01000007_gene2671	2.952e-64	224.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1ISPY@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_2307117_0	1341181.FLJC2902T_06080	0.0	1122.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia,2NSJJ@237|Flavobacterium	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DTH2_k127_2307117_4	1150600.ADIARSV_3468	3.17e-114	377.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
DTH2_k127_2307117_2	1202532.FF52_21879	3.288e-171	546.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1HXK5@117743|Flavobacteriia,2NTN7@237|Flavobacterium	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DTH2_k127_2307117_7	468059.AUHA01000007_gene2675	1.153e-102	338.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1IPBT@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
DTH2_k127_2307117_6	468059.AUHA01000007_gene2676	4.696e-105	347.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1IPGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
DTH2_k127_2307117_11	1121899.Q764_07530	2.44e-57	205.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia,2P06C@237|Flavobacterium	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
DTH2_k127_2307117_3	760192.Halhy_4776	5.514e-164	522.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1IPSN@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH2_k127_23513_0	929556.Solca_3852	1.561e-136	439.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_23513_1	1453500.AT05_08735	5.092e-50	184.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
DTH2_k127_2383922_1	1356852.N008_07605	2.581e-69	245.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_2383922_0	153721.MYP_961	1.705e-168	534.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,47JMK@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH2_k127_2383922_2	1120966.AUBU01000006_gene3289	3.601e-64	222.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
DTH2_k127_2384495_4	41431.PCC8801_2567	2.404e-20	97.0	28J0S@1|root,2Z8XX@2|Bacteria,1G3N4@1117|Cyanobacteria,3KHGW@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2384495_3	468059.AUHA01000003_gene1871	2.657e-89	309.0	COG2367@1|root,COG2367@2|Bacteria,4NH6K@976|Bacteroidetes,1INP4@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
DTH2_k127_2384495_0	1227739.Hsw_0453	4.936e-142	464.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,47NNC@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH2_k127_2384495_2	929556.Solca_2087	7.943e-115	379.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1IRSG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_2384495_1	991.IW20_04400	7.081e-130	417.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1HXDT@117743|Flavobacteriia,2NT1M@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH2_k127_2444013_3	700598.Niako_4358	2.812e-130	426.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1INWC@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DTH2_k127_2444013_2	319236.JCM19294_2611	9.168e-149	476.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1HX6M@117743|Flavobacteriia,3HK3F@363408|Nonlabens	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
DTH2_k127_2444013_11	1235802.C823_01010	7.748e-20	95.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,25XDA@186806|Eubacteriaceae	186801|Clostridia	L	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_2444013_4	865937.Gilli_3002	7.894e-110	366.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,1HY28@117743|Flavobacteriia,2P6JF@244698|Gillisia	976|Bacteroidetes	H	Aminotransferase class I and II	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_2444013_8	926549.KI421517_gene4099	2.918e-53	194.0	COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,47Q2B@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
DTH2_k127_2444013_1	468059.AUHA01000003_gene2023	1.369e-166	533.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes,1IP1U@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
DTH2_k127_2444013_10	1267211.KI669560_gene1759	9.191e-42	157.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,1IT04@117747|Sphingobacteriia	976|Bacteroidetes	Q	protein possibly involved in aromatic compounds catabolism	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
DTH2_k127_2444013_7	1123008.KB905705_gene914	1.735e-68	237.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,2FQY1@200643|Bacteroidia,22XUD@171551|Porphyromonadaceae	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
DTH2_k127_2444013_5	1492737.FEM08_26310	1.893e-96	320.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia,2NSSS@237|Flavobacterium	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
DTH2_k127_2444013_6	688270.Celal_1014	1.529e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,1F7QD@104264|Cellulophaga	976|Bacteroidetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_2444013_9	1270196.JCKI01000008_gene1654	3.762e-49	180.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISG3@117747|Sphingobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
DTH2_k127_2444013_0	992406.RIA_0437	5.991e-206	653.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_2533585_22	926562.Oweho_2105	1.183e-64	230.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia,2PC60@246874|Cryomorphaceae	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_2533585_10	1122621.ATZA01000006_gene691	1.704e-157	507.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,1IQWW@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase domain protein	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_2533585_0	714943.Mucpa_3278	0.0	1317.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1IQ2I@117747|Sphingobacteriia	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
DTH2_k127_2533585_12	1454007.JAUG01000064_gene335	1.362e-125	407.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1IREV@117747|Sphingobacteriia	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
DTH2_k127_2533585_13	926549.KI421517_gene3965	9.154e-123	400.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	ybiK	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_2533585_9	746697.Aeqsu_2879	2.482e-166	534.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1HWWM@117743|Flavobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
DTH2_k127_2533585_3	485918.Cpin_6916	4.181e-213	668.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DTH2_k127_2533585_4	929556.Solca_0295	1.978e-205	646.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1IP9V@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DTH2_k127_2533585_30	1008457.BAEX01000038_gene2910	7.886e-18	95.0	2EK9T@1|root,33E03@2|Bacteria,4NYU0@976|Bacteroidetes,1I5TG@117743|Flavobacteriia,47IEQ@76831|Myroides	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_2533585_27	153721.MYP_3155	1.178e-40	173.0	COG2885@1|root,COG2885@2|Bacteria,4NECX@976|Bacteroidetes,47NDN@768503|Cytophagia	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2533585_20	926562.Oweho_0866	1.734e-74	261.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia,2PAR4@246874|Cryomorphaceae	976|Bacteroidetes	K	NusB family	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DTH2_k127_2533585_11	1380384.JADN01000006_gene2683	1.57e-144	467.0	COG0334@1|root,COG0334@2|Bacteria,4NF3I@976|Bacteroidetes,1HX8R@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH2_k127_2533585_14	925409.KI911562_gene1864	2.048e-105	349.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH2_k127_2533585_8	555500.I215_04040	1.122e-169	546.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	res	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
DTH2_k127_2533585_7	1346330.M472_13530	3.572e-179	569.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_2533585_37	1385519.N801_08230	0.0001017	52.0	COG4978@1|root,COG4978@2|Bacteria,2IS9W@201174|Actinobacteria,4FHRK@85021|Intrasporangiaceae	201174|Actinobacteria	KT	family transcriptional regulator	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
DTH2_k127_2533585_24	886379.AEWI01000008_gene679	6.239e-51	189.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,2FMIT@200643|Bacteroidia,3XJZS@558415|Marinilabiliaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_2533585_29	468059.AUHA01000003_gene1899	1.113e-21	100.0	COG2146@1|root,COG2146@2|Bacteria,4NV9E@976|Bacteroidetes,1ITVU@117747|Sphingobacteriia	976|Bacteroidetes	P	Rieske (2Fe-2S) domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske,Rieske_2
DTH2_k127_2533585_17	1121129.KB903359_gene1938	3.222e-82	283.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,2FN1T@200643|Bacteroidia,22W9X@171551|Porphyromonadaceae	976|Bacteroidetes	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DTH2_k127_2533585_19	926556.Echvi_0142	3.917e-75	256.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
DTH2_k127_2533585_18	926562.Oweho_3347	3.077e-77	274.0	COG1368@1|root,COG1368@2|Bacteria,4PKS4@976|Bacteroidetes,1IMND@117743|Flavobacteriia	976|Bacteroidetes	M	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
DTH2_k127_2533585_23	1131269.AQVV01000028_gene28	1.343e-63	247.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
DTH2_k127_2533585_35	1107311.Q767_01605	1.197e-08	58.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2NSEK@237|Flavobacterium	976|Bacteroidetes	C	Dehydrogenase	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DTH2_k127_2533585_5	926562.Oweho_3015	1.078e-198	629.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2PB4N@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DTH2_k127_2533585_26	743722.Sph21_3658	1.206e-44	170.0	COG0084@1|root,COG0084@2|Bacteria,4NSGW@976|Bacteroidetes,1ITD3@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH2_k127_2533585_16	929562.Emtol_3698	1.566e-91	307.0	COG1179@1|root,COG1179@2|Bacteria,4NEKB@976|Bacteroidetes,47KQ6@768503|Cytophagia	976|Bacteroidetes	H	ThiF family	tcdA	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
DTH2_k127_2533585_36	1408433.JHXV01000009_gene1244	1.485e-05	55.0	2A33Q@1|root,30RIR@2|Bacteria,4PH5X@976|Bacteroidetes,1IHVQ@117743|Flavobacteriia,2PBYM@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2533585_2	1305737.JAFX01000001_gene3229	6.109e-237	742.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,47JQE@768503|Cytophagia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
DTH2_k127_2533585_15	649349.Lbys_0384	1.248e-102	366.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_2533585_28	1123248.KB893326_gene1365	7.034e-25	122.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_2533585_21	1408433.JHXV01000014_gene3673	1.597e-73	271.0	COG3291@1|root,COG3291@2|Bacteria,4PFQY@976|Bacteroidetes,1ICPB@117743|Flavobacteriia,2PBH6@246874|Cryomorphaceae	976|Bacteroidetes	S	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta
DTH2_k127_2533585_1	929556.Solca_3471	3.082e-275	863.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1IP0N@117747|Sphingobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DTH2_k127_2533585_32	1041826.FCOL_09370	9.585e-16	85.0	2AD0U@1|root,312NT@2|Bacteria,4PHMV@976|Bacteroidetes,1IDQF@117743|Flavobacteriia,2NYYD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2533585_31	755732.Fluta_2422	4.562e-17	88.0	29BEQ@1|root,2ZYD2@2|Bacteria,4PD0R@976|Bacteroidetes,1ICRX@117743|Flavobacteriia,2PBXT@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2533585_6	1089547.KB913013_gene3248	6.951e-191	609.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,47KCV@768503|Cytophagia	976|Bacteroidetes	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH2_k127_2533585_25	929556.Solca_0404	8.99e-50	188.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IT0W@117747|Sphingobacteriia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
DTH2_k127_2533585_33	929556.Solca_0487	1.118e-15	76.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH2_k127_2540818_2	1356852.N008_09475	0.0001846	44.0	2D6MI@1|root,32TMJ@2|Bacteria,4NPMS@976|Bacteroidetes,47Q9V@768503|Cytophagia	976|Bacteroidetes	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
DTH2_k127_2540818_0	1250006.JHZZ01000001_gene781	5.19e-51	187.0	COG3449@1|root,COG3449@2|Bacteria,4NMS1@976|Bacteroidetes,1I5E1@117743|Flavobacteriia,3VWKP@52959|Polaribacter	976|Bacteroidetes	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
DTH2_k127_2540818_1	1191523.MROS_0708	1.91e-38	151.0	2D6MI@1|root,32TMJ@2|Bacteria	2|Bacteria	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
DTH2_k127_2681136_5	502025.Hoch_1472	0.000154	49.0	COG3291@1|root,COG3325@1|root,COG3979@1|root,COG3291@2|Bacteria,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,437VC@68525|delta/epsilon subdivisions,2WYPH@28221|Deltaproteobacteria,2YUAF@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
DTH2_k127_2681136_1	945713.IALB_2577	4.036e-146	480.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
DTH2_k127_2681136_4	269798.CHU_2870	9.335e-05	54.0	COG3291@1|root,COG3391@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,P_proprotein,SprB,fn3
DTH2_k127_2681136_2	1484460.JSWG01000008_gene1892	2.481e-131	438.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH2_k127_2681136_3	643867.Ftrac_3640	5.961e-77	282.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,47TYP@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
DTH2_k127_2681136_0	1150600.ADIARSV_2511	0.0	1264.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH2_k127_2746494_0	1239962.C943_03441	0.0	1015.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_2746494_14	1122176.KB903534_gene2126	1.7e-70	244.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,1J079@117747|Sphingobacteriia	976|Bacteroidetes	P	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_2746494_16	755732.Fluta_1914	1.458e-45	175.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1IC3X@117743|Flavobacteriia,2PB1K@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_2746494_7	391596.PBAL39_06551	2.668e-100	332.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DTH2_k127_2746494_1	755732.Fluta_1117	1.934e-251	801.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia,2PAC5@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
DTH2_k127_2746494_15	525373.HMPREF0766_11567	3.015e-52	189.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_2746494_18	485918.Cpin_1054	9.195e-25	111.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1ITN8@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_2746494_21	762984.HMPREF9445_00776	8.642e-06	52.0	2EK3P@1|root,33DU3@2|Bacteria,4NU68@976|Bacteroidetes,2FMUD@200643|Bacteroidia,4AM0I@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG25370 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
DTH2_k127_2746494_11	929556.Solca_4343	6.369e-79	280.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_2746494_20	471854.Dfer_3773	1.776e-08	65.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
DTH2_k127_2746494_8	468059.AUHA01000002_gene1188	4.723e-98	342.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IR0N@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
DTH2_k127_2746494_4	926549.KI421517_gene1852	2.252e-144	464.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DTH2_k127_2746494_10	1250005.PHEL85_1831	6.57e-82	279.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia,3VV5P@52959|Polaribacter	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
DTH2_k127_2746494_5	1270196.JCKI01000003_gene1835	2.556e-103	342.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DTH2_k127_2746494_19	553175.POREN0001_1559	1.88e-17	84.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia,22YMK@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
DTH2_k127_2746494_2	1121957.ATVL01000008_gene4274	3.073e-180	571.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,47K8D@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_2746494_3	929703.KE386491_gene3162	5.784e-153	488.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH2_k127_2746494_12	153721.MYP_1295	4.004e-76	274.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47NKW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2746494_6	1408433.JHXV01000001_gene703	9.56e-102	342.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PC5X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
DTH2_k127_2746494_9	1150600.ADIARSV_2864	7.65e-95	330.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2746494_17	746697.Aeqsu_1551	6.109e-38	151.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1I1E3@117743|Flavobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
DTH2_k127_2746494_13	926562.Oweho_2451	1.931e-75	264.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,1HY9S@117743|Flavobacteriia,2PABC@246874|Cryomorphaceae	976|Bacteroidetes	T	periplasmic ligand-binding sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_2910975_26	1408433.JHXV01000006_gene2768	4.191e-54	199.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
DTH2_k127_2910975_4	525373.HMPREF0766_11425	4.911e-181	572.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DTH2_k127_2910975_36	1123277.KB893172_gene951	0.0009288	51.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
DTH2_k127_2910975_35	755732.Fluta_1495	0.0007019	51.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF2341,Laminin_G_3,PKD
DTH2_k127_2910975_8	929556.Solca_1245	1.984e-175	556.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DTH2_k127_2910975_30	1408433.JHXV01000001_gene946	1.387e-40	160.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia,2PB39@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_2910975_5	385682.AFSL01000006_gene2355	1.341e-180	585.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,2FMT4@200643|Bacteroidia,3XJ5D@558415|Marinilabiliaceae	976|Bacteroidetes	L	RecQ zinc-binding	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
DTH2_k127_2910975_1	1168034.FH5T_21195	1.181e-232	745.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,2G3GJ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_2910975_32	762903.Pedsa_1014	1.811e-11	66.0	2E35A@1|root,32Y59@2|Bacteria,4NVFH@976|Bacteroidetes,1IU6S@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2910975_0	1341181.FLJC2902T_28230	0.0	1094.0	COG0265@1|root,COG3291@1|root,COG4675@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,COG4675@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2P0S7@237|Flavobacterium	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
DTH2_k127_2910975_11	485917.Phep_1414	3.745e-133	428.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_2910975_6	1313301.AUGC01000010_gene956	2.841e-180	569.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes	976|Bacteroidetes	G	Aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DTH2_k127_2910975_28	927658.AJUM01000047_gene2816	9.866e-51	183.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_2910975_25	1408433.JHXV01000009_gene1312	8.506e-56	200.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,1ICQH@117743|Flavobacteriia,2PBRJ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2910975_33	929556.Solca_1982	2.861e-10	71.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,1IU2K@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2910975_7	1121904.ARBP01000006_gene4035	6.686e-180	602.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_2910975_9	1237149.C900_01149	7.854e-164	535.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_2910975_13	755732.Fluta_2055	2.326e-120	398.0	COG0438@1|root,COG0438@2|Bacteria,4PI5K@976|Bacteroidetes,1IGDT@117743|Flavobacteriia,2PB9M@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_2910975_23	869213.JCM21142_104191	9.519e-64	232.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,47KDM@768503|Cytophagia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_2910975_3	929556.Solca_2970	3.734e-183	581.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1IPF3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2910975_29	714943.Mucpa_6957	3.981e-46	174.0	2C6BU@1|root,32S87@2|Bacteria,4NRX1@976|Bacteroidetes,1ITDE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2910975_21	555500.I215_11434	4.179e-79	269.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1HY9T@117743|Flavobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
DTH2_k127_2910975_10	1121904.ARBP01000004_gene1065	1.335e-157	511.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH2_k127_2910975_12	929562.Emtol_2961	2.244e-120	395.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,47K2G@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
DTH2_k127_2910975_27	926562.Oweho_1092	2.64e-53	206.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2910975_34	620914.JH621261_gene916	1.211e-09	60.0	2DRFB@1|root,33BGM@2|Bacteria,4NXIN@976|Bacteroidetes,1I6SW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2910975_20	755732.Fluta_3069	1.91e-84	285.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,1HYIW@117743|Flavobacteriia,2PBST@246874|Cryomorphaceae	976|Bacteroidetes	T	Protein tyrosine phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
DTH2_k127_2910975_16	1356852.N008_16220	2.043e-89	300.0	COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,47XMI@768503|Cytophagia	976|Bacteroidetes	U	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DTH2_k127_2910975_18	1237149.C900_03670	2.309e-86	291.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,47KEA@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
DTH2_k127_2910975_22	927658.AJUM01000034_gene74	2.834e-68	237.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,2FRYA@200643|Bacteroidia,3XJ8R@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_2910975_19	1046627.BZARG_930	1.193e-85	297.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_2910975_24	425104.Ssed_0437	2.559e-59	212.0	COG0637@1|root,COG0637@2|Bacteria,1NF90@1224|Proteobacteria,1RNP8@1236|Gammaproteobacteria,2QAHF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	yniC	GO:0000287,GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050084,GO:0050286,GO:0050308,GO:0050309	3.1.3.23,5.4.2.6	ko:K01838,ko:K19270	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH2_k127_2910975_2	714943.Mucpa_1000	1.717e-200	628.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1INNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DTH2_k127_2910975_17	1408473.JHXO01000006_gene1066	7.891e-88	302.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_2910975_15	1408433.JHXV01000022_gene3146	3.201e-108	368.0	COG1807@1|root,COG1807@2|Bacteria,4NM44@976|Bacteroidetes,1IF0R@117743|Flavobacteriia,2PBBM@246874|Cryomorphaceae	976|Bacteroidetes	M	Alg9-like mannosyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22
DTH2_k127_2910975_14	867900.Celly_0991	8.817e-120	392.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1HXNI@117743|Flavobacteriia,1F7Z2@104264|Cellulophaga	976|Bacteroidetes	F	COGs COG0044 Dihydroorotase and related cyclic amidohydrolase	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH2_k127_2963958_9	10224.XP_006819552.1	2.569e-29	118.0	COG4992@1|root,KOG1402@2759|Eukaryota,38EEM@33154|Opisthokonta,3BC6G@33208|Metazoa,3CVEK@33213|Bilateria	33208|Metazoa	E	ornithine-oxo-acid transaminase activity	OAT	GO:0003008,GO:0003674,GO:0003824,GO:0003992,GO:0004587,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0007600,GO:0007601,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0031974,GO:0031981,GO:0032501,GO:0034214,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0050877,GO:0050953,GO:0051259,GO:0065003,GO:0070013,GO:0070279,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_2963958_0	760192.Halhy_3199	0.0	1177.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,1IWN3@117747|Sphingobacteriia	976|Bacteroidetes	P	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
DTH2_k127_2963958_2	760192.Halhy_3198	5.555e-216	687.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) multisubunit Na H antiporter MnhA subunit	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH2_k127_2963958_1	1434325.AZQN01000004_gene1740	3.89e-229	719.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
DTH2_k127_2963958_5	269798.CHU_1041	5.316e-83	281.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,47PCQ@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DTH2_k127_2963958_4	880071.Fleli_3472	9.819e-118	383.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47U0W@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
DTH2_k127_2963958_6	714943.Mucpa_1460	1.548e-70	242.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DTH2_k127_2963958_7	929556.Solca_4472	8.471e-43	162.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1IT35@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DTH2_k127_2963958_3	1120965.AUBV01000006_gene2422	6.192e-162	513.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,47KS2@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH2_k127_2963958_8	1392498.JQLH01000001_gene3183	9.21e-34	131.0	COG2827@1|root,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,1IGSP@117743|Flavobacteriia,2PIV2@252356|Maribacter	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_2963958_10	1244531.CIG1485E_0053	2.705e-05	49.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2YM9T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_2979248_18	1150600.ADIARSV_1799	9.143e-17	80.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1IP4T@117747|Sphingobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DTH2_k127_2979248_20	1122176.KB903566_gene3496	2.198e-05	57.0	COG3210@1|root,COG3291@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4PHJX@976|Bacteroidetes,1IW6U@117747|Sphingobacteriia	976|Bacteroidetes	MU	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
DTH2_k127_2979248_19	1121912.AUHD01000013_gene917	1.71e-12	81.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4PMR5@976|Bacteroidetes,1IKRQ@117743|Flavobacteriia	976|Bacteroidetes	N	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
DTH2_k127_2979248_22	984262.SGRA_1386	0.0008048	52.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF1080,MAM,PKD,SprB,fn3
DTH2_k127_2979248_17	391603.FBALC1_09277	3.619e-28	132.0	COG3291@1|root,COG4447@1|root,COG4625@1|root,COG5492@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,4PMR5@976|Bacteroidetes,1IJX3@117743|Flavobacteriia	976|Bacteroidetes	N	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
DTH2_k127_2979248_12	1484460.JSWG01000006_gene3028	2.975e-59	235.0	COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3866@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
DTH2_k127_2979248_21	984262.SGRA_0439	0.0006332	52.0	COG3291@1|root,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes	976|Bacteroidetes	MU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PKD
DTH2_k127_2979248_13	1313421.JHBV01000003_gene602	4.698e-57	202.0	COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes,1IXUP@117747|Sphingobacteriia	976|Bacteroidetes	L	Pfam:DUF59	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
DTH2_k127_2979248_9	755732.Fluta_2685	1.401e-80	293.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_2979248_8	926562.Oweho_2263	1.632e-90	304.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1I05P@117743|Flavobacteriia,2PAWE@246874|Cryomorphaceae	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
DTH2_k127_2979248_15	1123255.JHYS01000007_gene1670	2.754e-37	142.0	COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,2VSR2@28216|Betaproteobacteria,4AEMJ@80864|Comamonadaceae	28216|Betaproteobacteria	Q	TIGRFAM phenylacetate-CoA oxygenase, PaaH subunit	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
DTH2_k127_2979248_4	1122929.KB908240_gene306	2.185e-155	495.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TTC4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phenylacetate-CoA oxygenase	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
DTH2_k127_2979248_7	1122176.KB903619_gene5315	1.784e-115	387.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,1INQ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DTH2_k127_2979248_2	929556.Solca_2813	4.565e-278	867.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
DTH2_k127_2979248_0	1111730.ATTM01000007_gene2449	0.0	1079.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
DTH2_k127_2979248_1	1341181.FLJC2902T_00590	2.148e-293	922.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,1HX95@117743|Flavobacteriia,2NTHP@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH2_k127_2979248_11	1500281.JQKZ01000041_gene471	1.636e-65	230.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1I1FE@117743|Flavobacteriia,3ZNZH@59732|Chryseobacterium	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
DTH2_k127_2979248_5	1111730.ATTM01000001_gene1477	8.749e-154	491.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_2979248_3	1341181.FLJC2902T_00630	4.859e-212	672.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
DTH2_k127_2979248_14	700598.Niako_6523	1.954e-49	181.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1IS9I@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_2979248_10	1229487.AMYW01000003_gene1973	9.809e-78	264.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia,2NUTM@237|Flavobacterium	976|Bacteroidetes	S	YeeE YedE family protein	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_2979248_6	760192.Halhy_5148	4.168e-149	485.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
DTH2_k127_2979248_16	468059.AUHA01000008_gene2762	8.269e-31	122.0	COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,1IRFX@117747|Sphingobacteriia	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH2_k127_2979723_43	1121957.ATVL01000014_gene1421	1.174e-07	57.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
DTH2_k127_2979723_14	468059.AUHA01000004_gene2240	2.146e-130	424.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_2979723_23	313606.M23134_02864	4.591e-75	258.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
DTH2_k127_2979723_20	1408433.JHXV01000036_gene237	3.353e-83	283.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia,2PANE@246874|Cryomorphaceae	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
DTH2_k127_2979723_12	1168034.FH5T_05640	4.135e-135	439.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,2FMW2@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
DTH2_k127_2979723_34	153721.MYP_190	1.299e-33	137.0	2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2979723_21	1121097.JCM15093_3154	4.611e-78	274.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,2FN2X@200643|Bacteroidia,4AMFE@815|Bacteroidaceae	976|Bacteroidetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
DTH2_k127_2979723_16	755732.Fluta_2847	6.344e-114	372.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia,2PA74@246874|Cryomorphaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_2979723_24	1168034.FH5T_16645	4.968e-69	238.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,2FP0F@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_2979723_44	743722.Sph21_3918	0.00026	51.0	2DQR9@1|root,3387K@2|Bacteria,4NUR8@976|Bacteroidetes,1ITZY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2979723_39	755732.Fluta_3307	1.251e-18	91.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia,2PB9P@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2979723_42	1158294.JOMI01000001_gene1579	7.555e-09	67.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,2FNM2@200643|Bacteroidia	976|Bacteroidetes	N	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
DTH2_k127_2979723_11	929556.Solca_4375	4.95e-140	449.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
DTH2_k127_2979723_37	1121904.ARBP01000007_gene3025	3.019e-19	97.0	28MPU@1|root,2ZAYW@2|Bacteria,4NRQD@976|Bacteroidetes,47NJK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2979723_29	1313421.JHBV01000043_gene3031	8.161e-48	174.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1ISTX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
DTH2_k127_2979723_18	1150621.SMUL_0008	7.863e-94	313.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2YMMB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DTH2_k127_2979723_19	402612.FP1585	1.028e-86	289.0	COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1I1AG@117743|Flavobacteriia,2NU4Y@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
DTH2_k127_2979723_10	1122225.AULQ01000012_gene480	4.235e-143	467.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_2979723_41	762968.HMPREF9441_01985	1.366e-10	65.0	COG5512@1|root,COG5512@2|Bacteria,4NSDR@976|Bacteroidetes,2FTCM@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
DTH2_k127_2979723_15	1408813.AYMG01000015_gene5005	4.184e-127	416.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,1IP1J@117747|Sphingobacteriia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
DTH2_k127_2979723_28	1408473.JHXO01000008_gene2782	3.118e-49	184.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
DTH2_k127_2979723_26	1305737.JAFX01000001_gene2728	1.717e-64	224.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,47PCJ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DTH2_k127_2979723_4	860228.Ccan_15870	2.234e-202	639.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia,1EQ9H@1016|Capnocytophaga	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DTH2_k127_2979723_35	309799.DICTH_0563	1.586e-31	140.0	COG0392@1|root,COG5305@1|root,COG0392@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM,PMT_2
DTH2_k127_2979723_13	1121904.ARBP01000004_gene1136	1.242e-131	433.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,47JTX@768503|Cytophagia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
DTH2_k127_2979723_1	1150600.ADIARSV_1022	1.109e-310	973.0	COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
DTH2_k127_2979723_3	755732.Fluta_2284	2.215e-207	654.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia,2PAFK@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_2979723_7	1358423.N180_07310	2.821e-163	524.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
DTH2_k127_2979723_31	468059.AUHA01000002_gene481	2.744e-42	160.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,1ISX2@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
DTH2_k127_2979723_38	755732.Fluta_2281	5.285e-19	98.0	2ABIA@1|root,310ZH@2|Bacteria,4PFMS@976|Bacteroidetes,1ICAQ@117743|Flavobacteriia,2PB8S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2979723_40	385682.AFSL01000079_gene1030	2.858e-16	83.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia,3XK7W@558415|Marinilabiliaceae	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
DTH2_k127_2979723_8	929556.Solca_2028	1.144e-162	522.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_2979723_30	926562.Oweho_2802	5.803e-45	175.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_2979723_6	755732.Fluta_2288	8.102e-167	539.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia,2PAKH@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_2979723_25	755732.Fluta_2289	3.043e-67	237.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,1HYV7@117743|Flavobacteriia,2PAW7@246874|Cryomorphaceae	976|Bacteroidetes	S	Gliding motility protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2979723_22	929556.Solca_3321	1.019e-77	280.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
DTH2_k127_2979723_27	869213.JCM21142_52127	1.698e-58	213.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes	976|Bacteroidetes	S	gliding motility	gldN	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2979723_9	886377.Murru_1865	1.13e-147	474.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
DTH2_k127_2979723_2	1227739.Hsw_3214	1.953e-234	750.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_2979723_17	700598.Niako_4616	1.023e-105	348.0	COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1IWGI@117747|Sphingobacteriia	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
DTH2_k127_2979723_5	1150600.ADIARSV_1900	5.855e-180	581.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
DTH2_k127_2979723_32	1123248.KB893359_gene2070	1.655e-39	153.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,1IT8Z@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
DTH2_k127_2979723_33	1223410.KN050846_gene1458	3.857e-39	153.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia	976|Bacteroidetes	FH	Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
DTH2_k127_2979723_0	468059.AUHA01000004_gene2361	0.0	1256.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1IQP6@117747|Sphingobacteriia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DTH2_k127_2997003_0	313606.M23134_05475	0.0	1937.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
DTH2_k127_2997003_6	1408433.JHXV01000026_gene3016	2.037e-34	138.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1I253@117743|Flavobacteriia,2PB3I@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2997003_4	1286632.P278_05080	5.333e-85	298.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,1HXB9@117743|Flavobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DTH2_k127_2997003_1	313606.M23134_06836	0.0	1122.0	COG2185@1|root,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,47JW5@768503|Cytophagia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
DTH2_k127_2997003_3	755732.Fluta_1284	1.672e-97	345.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_2997003_5	313606.M23134_06668	2.59e-40	153.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,47R8I@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_2997003_2	649349.Lbys_0863	3.771e-238	747.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,47K8Q@768503|Cytophagia	976|Bacteroidetes	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
DTH2_k127_3196902_5	402612.FP0688	1.645e-92	345.0	COG3291@1|root,COG3405@1|root,COG3291@2|Bacteria,COG3405@2|Bacteria,4NDZC@976|Bacteroidetes,1IJY5@117743|Flavobacteriia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3196902_18	388413.ALPR1_16369	2.4e-28	132.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_3196902_24	118173.KB235914_gene2329	0.0001347	53.0	COG3551@1|root,COG4122@1|root,COG3551@2|Bacteria,COG4122@2|Bacteria,1GKUR@1117|Cyanobacteria,1HEYB@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_3196902_6	76114.ebA4327	2.155e-88	304.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VP70@28216|Betaproteobacteria,2KYFB@206389|Rhodocyclales	206389|Rhodocyclales	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_3196902_10	1280950.HJO_04220	1.112e-71	260.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
DTH2_k127_3196902_23	886293.Sinac_1596	9.442e-09	61.0	COG0236@1|root,COG0236@2|Bacteria,2J1MP@203682|Planctomycetes	203682|Planctomycetes	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH2_k127_3196902_12	592029.DDD_2273	8.378e-50	188.0	2EWJQ@1|root,33PXW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3196902_22	504472.Slin_4266	8.66e-11	70.0	COG1670@1|root,COG1670@2|Bacteria,4NW7K@976|Bacteroidetes,47T32@768503|Cytophagia	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_3196902_11	1142394.PSMK_04310	7.435e-62	224.0	COG0463@1|root,COG0463@2|Bacteria,2IYUR@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
DTH2_k127_3196902_15	457424.BFAG_03965	1.847e-47	179.0	COG1028@1|root,COG1028@2|Bacteria,4NN4M@976|Bacteroidetes,2FS25@200643|Bacteroidia,4AT98@815|Bacteroidaceae	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH2_k127_3196902_3	1506583.JQJY01000005_gene2364	1.833e-110	368.0	COG0332@1|root,COG0332@2|Bacteria,4NFMX@976|Bacteroidetes,1IIN6@117743|Flavobacteriia,2NV2R@237|Flavobacterium	976|Bacteroidetes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_3196902_21	742727.HMPREF9447_00863	6.027e-13	71.0	COG0236@1|root,COG0236@2|Bacteria,4NWWS@976|Bacteroidetes,2FUXS@200643|Bacteroidia,4AS4D@815|Bacteroidaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH2_k127_3196902_16	1541065.JRFE01000023_gene3778	2.695e-33	140.0	2E63H@1|root,330SK@2|Bacteria,1G9PE@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
DTH2_k127_3196902_17	313612.L8106_07606	9.105e-33	138.0	COG0500@1|root,COG2226@2|Bacteria,1G2V9@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
DTH2_k127_3196902_13	1121904.ARBP01000002_gene6716	4.779e-48	187.0	COG0438@1|root,COG0438@2|Bacteria,4NE0W@976|Bacteroidetes,47NIW@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_3196902_14	1237149.C900_03017	1.41e-47	181.0	COG0457@1|root,COG0457@2|Bacteria,4PPR7@976|Bacteroidetes	976|Bacteroidetes	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3196902_9	493475.GARC_5135	2.146e-78	291.0	COG1696@1|root,COG1696@2|Bacteria	2|Bacteria	M	negative regulation of protein lipidation	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH2_k127_3196902_19	118168.MC7420_6994	5.199e-28	123.0	COG0500@1|root,COG2226@2|Bacteria,1GQVD@1117|Cyanobacteria	1117|Cyanobacteria	Q	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
DTH2_k127_3196902_1	1168034.FH5T_09635	8.141e-168	534.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_3196902_8	153721.MYP_4776	8.893e-79	274.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,47K3H@768503|Cytophagia	976|Bacteroidetes	FP	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
DTH2_k127_3196902_2	755732.Fluta_1682	9.607e-145	501.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_3196902_20	860228.Ccan_11240	2.062e-23	108.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia,1ER40@1016|Capnocytophaga	976|Bacteroidetes	CO	Redoxin family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
DTH2_k127_3196902_4	1443665.JACA01000070_gene3194	8.747e-107	356.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ83@117743|Flavobacteriia,2YGMK@290174|Aquimarina	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_3196902_7	1317122.ATO12_02590	2.542e-88	306.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia,2YHU7@290174|Aquimarina	976|Bacteroidetes	V	ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_3196902_0	643867.Ftrac_2815	2.77e-307	954.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_3309812_10	755732.Fluta_1464	2.123e-91	307.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia,2PA8A@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH2_k127_3309812_20	1358423.N180_14265	5.211e-14	74.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IZWK@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_3309812_19	1313421.JHBV01000005_gene4605	3.795e-22	101.0	2DRDD@1|root,33BAA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3309812_12	880071.Fleli_3147	1.018e-64	223.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DTH2_k127_3309812_21	1237149.C900_04898	4.722e-07	51.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Succinylglutamate desuccinylase Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
DTH2_k127_3309812_14	1121889.AUDM01000013_gene1874	9.835e-53	203.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,2NV0G@237|Flavobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_3309812_9	1237149.C900_04898	2.657e-92	312.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Succinylglutamate desuccinylase Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
DTH2_k127_3309812_5	1121011.AUCB01000006_gene998	1.358e-130	422.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia,23I6Q@178469|Arenibacter	976|Bacteroidetes	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
DTH2_k127_3309812_16	1121904.ARBP01000002_gene7254	1.697e-35	141.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
DTH2_k127_3309812_11	153721.MYP_4847	9.569e-70	250.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia	976|Bacteroidetes	E	PFAM FAD dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH2_k127_3309812_22	1121895.Q765_04315	2.489e-05	53.0	COG2350@1|root,COG2350@2|Bacteria,4NR5W@976|Bacteroidetes,1I5PD@117743|Flavobacteriia,2NU9F@237|Flavobacterium	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3309812_1	1408433.JHXV01000016_gene1828	2.779e-248	806.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia,2PA94@246874|Cryomorphaceae	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3309812_6	1121373.KB903621_gene1905	6.753e-116	377.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,47KRK@768503|Cytophagia	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DTH2_k127_3309812_4	153721.MYP_1661	9.827e-167	542.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,47NYD@768503|Cytophagia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_3309812_13	1236504.HMPREF2132_03480	4.338e-57	206.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,2FM5H@200643|Bacteroidia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
DTH2_k127_3309812_3	391596.PBAL39_20685	1.199e-180	581.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,HHH_8,PHP
DTH2_k127_3309812_2	468059.AUHA01000002_gene248	2.665e-196	623.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_3309812_18	1313421.JHBV01000027_gene1790	1.94e-30	130.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3309812_8	926562.Oweho_2268	7.198e-96	326.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia,2PA8I@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
DTH2_k127_3309812_7	929556.Solca_0555	3.052e-106	349.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_3309812_0	1121897.AUGO01000006_gene693	1.276e-256	800.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1I02U@117743|Flavobacteriia,2NSVU@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
DTH2_k127_3309812_17	1408433.JHXV01000001_gene1086	2.361e-31	140.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3309812_15	1185876.BN8_05964	3.016e-46	170.0	COG0454@1|root,COG0456@2|Bacteria,4NQDY@976|Bacteroidetes,47QNQ@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DTH2_k127_3494480_3	1004149.AFOE01000041_gene1129	3.753e-235	741.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_3494480_16	984262.SGRA_0341	2.002e-101	346.0	COG1807@1|root,COG1807@2|Bacteria,4NP7Y@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_48	269798.CHU_3639	3.202e-12	77.0	2C2MT@1|root,347EH@2|Bacteria,4P6C0@976|Bacteroidetes,47VTR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_36	555500.I215_07007	4.24e-36	138.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1I3ZI@117743|Flavobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DTH2_k127_3494480_1	1454007.JAUG01000013_gene2346	1.107e-303	945.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1INMK@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DTH2_k127_3494480_41	755732.Fluta_2355	3.201e-25	110.0	2ED7H@1|root,33743@2|Bacteria,4NYV3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_44	755732.Fluta_3614	3.299e-20	102.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_31	1121104.AQXH01000002_gene783	9.672e-46	174.0	2CWY1@1|root,32T0M@2|Bacteria,4P319@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_9	929556.Solca_4041	4.689e-143	464.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_3494480_12	1123059.KB823013_gene496	4.32e-127	418.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
DTH2_k127_3494480_19	929556.Solca_2424	2.519e-92	318.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1IPU4@117747|Sphingobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_3494480_38	938709.AUSH02000051_gene305	1.092e-27	127.0	COG1361@1|root,COG2911@1|root,COG4886@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4886@2|Bacteria,4NJQ1@976|Bacteroidetes	976|Bacteroidetes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,Laminin_G_3
DTH2_k127_3494480_50	1120951.AUBG01000019_gene1691	1.948e-05	57.0	COG2706@1|root,COG3227@1|root,COG2706@2|Bacteria,COG3227@2|Bacteria,4PP03@976|Bacteroidetes,1I8YI@117743|Flavobacteriia	976|Bacteroidetes	EG	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_3494480_17	926562.Oweho_3400	6.027e-100	340.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1HY3Q@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
DTH2_k127_3494480_28	762903.Pedsa_2033	4.049e-59	212.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
DTH2_k127_3494480_7	929556.Solca_3901	5.902e-161	517.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IWSF@117747|Sphingobacteriia	976|Bacteroidetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH2_k127_3494480_45	880070.Cycma_1076	4.931e-13	75.0	2E5FG@1|root,33075@2|Bacteria,4NWB7@976|Bacteroidetes,47QE3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_30	755732.Fluta_2239	4.812e-50	186.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1I188@117743|Flavobacteriia,2PAUK@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
DTH2_k127_3494480_46	224308.BSU23680	1.962e-12	70.0	COG2329@1|root,COG2329@2|Bacteria,1VAM1@1239|Firmicutes,4HJD7@91061|Bacilli,1ZHXP@1386|Bacillus	91061|Bacilli	S	enzyme involved in biosynthesis of extracellular polysaccharides	yqjZ	-	-	-	-	-	-	-	-	-	-	-	ABM
DTH2_k127_3494480_22	755732.Fluta_0907	1.266e-84	305.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_3494480_0	1121285.AUFK01000013_gene2527	0.0	1036.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia,3ZNRY@59732|Chryseobacterium	976|Bacteroidetes	CI	Phenylacetic acid degradation protein PaaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
DTH2_k127_3494480_18	313606.M23134_02965	5.782e-96	339.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NJKM@976|Bacteroidetes,47NZZ@768503|Cytophagia	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_3494480_27	385682.AFSL01000024_gene2061	1.561e-63	234.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,2G0DG@200643|Bacteroidia,3XJHT@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_3494480_47	1313421.JHBV01000046_gene246	3.163e-12	75.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1IUMP@117747|Sphingobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
DTH2_k127_3494480_23	929556.Solca_2806	2.605e-70	244.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_3494480_11	468059.AUHA01000003_gene1795	8.702e-131	428.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,1IQMR@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
DTH2_k127_3494480_35	1191523.MROS_1520	3.242e-36	143.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
DTH2_k127_3494480_4	1168034.FH5T_10945	2.389e-227	723.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,2FM68@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
DTH2_k127_3494480_20	1094980.Mpsy_0919	1.799e-91	309.0	COG0248@1|root,arCOG05138@2157|Archaea,2XZYT@28890|Euryarchaeota,2NAE7@224756|Methanomicrobia	224756|Methanomicrobia	F	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
DTH2_k127_3494480_24	926562.Oweho_3344	8.131e-70	245.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
DTH2_k127_3494480_6	929556.Solca_2919	1.422e-217	692.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH2_k127_3494480_25	755732.Fluta_2596	1.202e-68	248.0	COG3920@1|root,COG3920@2|Bacteria,4NP4X@976|Bacteroidetes,1I22K@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2,TPR_8
DTH2_k127_3494480_39	1237149.C900_05476	2.219e-27	127.0	COG3391@1|root,COG3391@2|Bacteria,4NZAU@976|Bacteroidetes,47Y1X@768503|Cytophagia	976|Bacteroidetes	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_51	1123276.KB893268_gene4978	0.0002351	53.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NF7B@976|Bacteroidetes,47MQS@768503|Cytophagia	976|Bacteroidetes	G	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD,RicinB_lectin_2
DTH2_k127_3494480_10	313606.M23134_01935	2.681e-133	432.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
DTH2_k127_3494480_29	1004149.AFOE01000050_gene2626	4.112e-52	190.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1I185@117743|Flavobacteriia	976|Bacteroidetes	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
DTH2_k127_3494480_49	929562.Emtol_2807	7.656e-07	60.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,47PSA@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
DTH2_k127_3494480_8	1150600.ADIARSV_2542	2.792e-144	471.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1IQPT@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
DTH2_k127_3494480_13	1538644.KO02_06925	1.359e-123	406.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_3494480_21	153721.MYP_2943	1.146e-90	312.0	28HAZ@1|root,2Z7N5@2|Bacteria,4NH23@976|Bacteroidetes,47MQC@768503|Cytophagia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_34	153721.MYP_2944	1.099e-39	154.0	2CGGN@1|root,2ZX47@2|Bacteria,4NNTI@976|Bacteroidetes,47QF4@768503|Cytophagia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_2	153721.MYP_2945	6.73e-280	902.0	COG1511@1|root,COG1511@2|Bacteria,4PKNX@976|Bacteroidetes,47XXR@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3584)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3584
DTH2_k127_3494480_26	391625.PPSIR1_31188	5.065e-67	248.0	COG0644@1|root,COG0644@2|Bacteria,1MZ3Z@1224|Proteobacteria	1224|Proteobacteria	C	Halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
DTH2_k127_3494480_52	216432.CA2559_00975	0.0005911	49.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_3494480_5	755732.Fluta_1214	2.201e-223	696.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1HXPE@117743|Flavobacteriia,2PA8D@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
DTH2_k127_3494480_42	1121373.KB903638_gene896	1.09e-22	106.0	298K1@1|root,2ZVQX@2|Bacteria,4NNNX@976|Bacteroidetes,47Q8A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3494480_15	929562.Emtol_3719	6.224e-107	367.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,47KS3@768503|Cytophagia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	aprX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_3494480_14	468059.AUHA01000003_gene1846	8.111e-120	397.0	COG0477@1|root,COG2814@2|Bacteria,4NEQU@976|Bacteroidetes,1IP74@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_3494480_33	1121957.ATVL01000009_gene1392	5.887e-43	160.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DTH2_k127_3494480_32	1121889.AUDM01000003_gene2448	5.811e-44	164.0	COG2153@1|root,COG2153@2|Bacteria,4NQPR@976|Bacteroidetes,1I23R@117743|Flavobacteriia,2NW28@237|Flavobacterium	976|Bacteroidetes	S	GNAT family acetyltransferase	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
DTH2_k127_3494480_37	313606.M23134_07146	2.448e-29	122.0	COG0328@1|root,COG0328@2|Bacteria,4NZ41@976|Bacteroidetes,47T0B@768503|Cytophagia	976|Bacteroidetes	L	RNase H	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H
DTH2_k127_3494480_40	1121012.AUKX01000004_gene3541	3.667e-26	108.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,1I55S@117743|Flavobacteriia,23HN4@178469|Arenibacter	976|Bacteroidetes	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
DTH2_k127_3494480_43	869213.JCM21142_31015	4.512e-22	109.0	COG4783@1|root,COG4783@2|Bacteria,4PP6D@976|Bacteroidetes	976|Bacteroidetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
DTH2_k127_3498860_2	867900.Celly_3098	1.524e-88	315.0	COG4733@1|root,COG4733@2|Bacteria,4NF53@976|Bacteroidetes,1I0AR@117743|Flavobacteriia,1FAMR@104264|Cellulophaga	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3498860_0	1237149.C900_02320	5.483e-158	533.0	COG0419@1|root,COG0419@2|Bacteria,4NGQP@976|Bacteroidetes,47MNH@768503|Cytophagia	976|Bacteroidetes	L	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3498860_1	1237149.C900_02314	1.483e-124	417.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3653888_2	1121373.KB903633_gene742	2.502e-15	86.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,47TT9@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_3653888_0	1408433.JHXV01000001_gene732	3.02e-120	406.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,1IMQQ@117743|Flavobacteriia,2PBFK@246874|Cryomorphaceae	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_3653888_1	1235803.C825_02831	7.85e-27	111.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,2FTW4@200643|Bacteroidia,22YCU@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
DTH2_k127_3653888_3	1123278.KB893547_gene4926	5.698e-05	53.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NGEP@976|Bacteroidetes,47NK0@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_3697274_6	1408433.JHXV01000007_gene2958	2.343e-60	215.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia,2PAZY@246874|Cryomorphaceae	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH2_k127_3697274_5	1123248.KB893318_gene4171	1.815e-116	378.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH2_k127_3697274_7	1185876.BN8_04403	6.572e-60	215.0	COG1496@1|root,COG1496@2|Bacteria,4NM9H@976|Bacteroidetes,47JW0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
DTH2_k127_3697274_4	1004149.AFOE01000048_gene33	1.729e-168	537.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DTH2_k127_3697274_0	1168034.FH5T_18860	0.0	1191.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,2FW95@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
DTH2_k127_3697274_9	929556.Solca_4221	7.966e-44	164.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1ITJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3697274_8	762903.Pedsa_2755	2.104e-54	199.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DTH2_k127_3697274_2	468059.AUHA01000002_gene980	1.525e-201	634.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_3697274_10	927658.AJUM01000034_gene225	1.109e-34	133.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,2FTWG@200643|Bacteroidia,3XKCJ@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_3697274_11	521097.Coch_1263	2.579e-33	134.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1I2U1@117743|Flavobacteriia,1ERCR@1016|Capnocytophaga	976|Bacteroidetes	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
DTH2_k127_3697274_3	1121129.KB903360_gene3054	7.401e-188	594.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,2FNJF@200643|Bacteroidia,22WBR@171551|Porphyromonadaceae	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DTH2_k127_3697274_1	743722.Sph21_1608	4.648e-314	986.0	COG0532@1|root,COG3115@1|root,COG0532@2|Bacteria,COG3115@2|Bacteria,4NGP3@976|Bacteroidetes,1IQ0V@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
DTH2_k127_37641_23	1313421.JHBV01000014_gene3816	3.182e-17	89.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4NRAB@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calycin_like,PCMD
DTH2_k127_37641_2	755732.Fluta_1488	4.1e-226	725.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_37641_7	762903.Pedsa_2225	6.249e-132	444.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1IPKB@117747|Sphingobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
DTH2_k127_37641_21	1408433.JHXV01000044_gene3183	2.287e-57	208.0	COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,1ICQF@117743|Flavobacteriia,2PBRF@246874|Cryomorphaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
DTH2_k127_37641_6	1408433.JHXV01000044_gene3184	7.806e-148	497.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
DTH2_k127_37641_13	1453500.AT05_09095	1.821e-72	250.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
DTH2_k127_37641_16	755732.Fluta_2051	1.661e-70	251.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
DTH2_k127_37641_14	1392489.JPOL01000002_gene885	1.955e-72	260.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia,2XI9K@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
DTH2_k127_37641_0	1107311.Q767_04445	0.0	1355.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia,2NSAK@237|Flavobacterium	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH2_k127_37641_19	269798.CHU_1710	1.023e-66	252.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_37641_18	1121918.ARWE01000001_gene309	4.923e-67	238.0	COG1284@1|root,COG1284@2|Bacteria,1R59F@1224|Proteobacteria,42P6M@68525|delta/epsilon subdivisions,2WKCS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
DTH2_k127_37641_24	1218103.CIN01S_12_00190	7.555e-17	92.0	2BJ8S@1|root,32DIE@2|Bacteria,4PPTN@976|Bacteroidetes,1IKTI@117743|Flavobacteriia,3ZSP1@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_37641_22	1506583.JQJY01000004_gene3024	2.647e-51	186.0	COG3708@1|root,COG3708@2|Bacteria,4NQ46@976|Bacteroidetes,1I45F@117743|Flavobacteriia,2NW6B@237|Flavobacterium	976|Bacteroidetes	K	transcription activator, effector binding	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
DTH2_k127_37641_1	1408433.JHXV01000034_gene18	3.646e-276	871.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia,2PAG3@246874|Cryomorphaceae	976|Bacteroidetes	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH2_k127_37641_4	755732.Fluta_2846	7.556e-202	639.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1I8AX@117743|Flavobacteriia,2PAB3@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
DTH2_k127_37641_20	1121904.ARBP01000005_gene4844	2.315e-66	240.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47N2D@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
DTH2_k127_37641_3	1408433.JHXV01000006_gene2788	2.302e-217	710.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_37641_9	926562.Oweho_2422	7.279e-102	336.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
DTH2_k127_37641_12	1484460.JSWG01000016_gene1617	1.17e-78	273.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1HZYF@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
DTH2_k127_37641_8	468059.AUHA01000003_gene1815	1.993e-128	416.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_37641_5	929703.KE386491_gene2331	5.063e-153	492.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47JT9@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_37641_11	929556.Solca_1904	3.13e-90	301.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_37641_17	643867.Ftrac_2549	7.887e-69	246.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
DTH2_k127_37641_10	1288963.ADIS_0367	2.183e-97	323.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_37641_15	1341155.FSS13T_25370	1.006e-71	262.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,4PKT1@976|Bacteroidetes,1I02G@117743|Flavobacteriia,2NV5H@237|Flavobacterium	976|Bacteroidetes	O	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
DTH2_k127_37699_17	755732.Fluta_2725	3.365e-54	219.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
DTH2_k127_37699_3	755732.Fluta_1894	6.138e-232	726.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1HXDR@117743|Flavobacteriia,2PA65@246874|Cryomorphaceae	976|Bacteroidetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DTH2_k127_37699_25	714943.Mucpa_4956	2.67e-29	121.0	2CCSR@1|root,32RWC@2|Bacteria,4NUMI@976|Bacteroidetes,1ITWM@117747|Sphingobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_37699_6	755732.Fluta_1895	1.53e-177	560.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia,2PACA@246874|Cryomorphaceae	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DTH2_k127_37699_16	1408473.JHXO01000011_gene2963	1.515e-58	213.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DTH2_k127_37699_22	714943.Mucpa_4284	2.35e-32	132.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_37699_4	1229276.DI53_2839	1.18e-190	613.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,1IQ2C@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
DTH2_k127_37699_11	1121129.KB903359_gene1547	1.957e-124	412.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,2FNA1@200643|Bacteroidia,22W55@171551|Porphyromonadaceae	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
DTH2_k127_37699_14	1408433.JHXV01000021_gene1665	1.919e-74	257.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IMQY@117743|Flavobacteriia,2PBHE@246874|Cryomorphaceae	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
DTH2_k127_37699_7	1270196.JCKI01000008_gene1294	2.754e-177	562.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DTH2_k127_37699_8	755732.Fluta_0800	2.454e-163	547.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia,2PAQ0@246874|Cryomorphaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
DTH2_k127_37699_20	755732.Fluta_0799	9.947e-51	189.0	28NAE@1|root,2ZBE7@2|Bacteria,4NJNX@976|Bacteroidetes,1I6YH@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
DTH2_k127_37699_18	1121459.AQXE01000011_gene2381	2.878e-52	196.0	COG1266@1|root,COG1266@2|Bacteria,1PD7P@1224|Proteobacteria,435PI@68525|delta/epsilon subdivisions,2X03C@28221|Deltaproteobacteria,2MA9B@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DTH2_k127_37699_9	929562.Emtol_1511	6.56e-132	423.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
DTH2_k127_37699_24	402612.FP0094	1.4e-29	122.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1IJY3@117743|Flavobacteriia,2P0P9@237|Flavobacterium	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_37699_0	1434325.AZQN01000003_gene2014	0.0	1168.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_37699_13	1358423.N180_07170	1.814e-78	269.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1ISIA@117747|Sphingobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
DTH2_k127_37699_2	1121373.KB903622_gene2826	3.528e-250	785.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,47KUE@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DTH2_k127_37699_15	714943.Mucpa_3116	6.403e-69	239.0	COG0586@1|root,COG0586@2|Bacteria,4NMBP@976|Bacteroidetes,1IRXI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH2_k127_37699_5	485917.Phep_0187	2.652e-184	597.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
DTH2_k127_37699_1	762903.Pedsa_2820	3.836e-291	904.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DTH2_k127_37699_12	761193.Runsl_5128	2.609e-100	340.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,47JIE@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_37699_23	1336803.PHEL49_0870	1.627e-30	124.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia,3VWPW@52959|Polaribacter	976|Bacteroidetes	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DTH2_k127_37699_28	391596.PBAL39_09631	2.052e-07	55.0	2ACEV@1|root,3120D@2|Bacteria,4PGV7@976|Bacteroidetes,1IUFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_37699_26	1296415.JACC01000021_gene4194	5.56e-22	100.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia,2YJJ1@290174|Aquimarina	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
DTH2_k127_37699_10	1120965.AUBV01000003_gene444	1.655e-124	410.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,47NAK@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM ribosomal RNA small subunit methyltransferase RsmB	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
DTH2_k127_37699_21	565034.BHWA1_01941	1.769e-38	161.0	COG0457@1|root,COG0457@2|Bacteria	565034.BHWA1_01941|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_37699_19	1107311.Q767_01615	4.366e-52	207.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
DTH2_k127_37699_27	1237149.C900_00773	6.355e-10	72.0	COG3209@1|root,COG3291@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	espK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07004,ko:K18491,ko:K20276	ko02024,ko04550,map02024,map04550	-	-	-	ko00000,ko00001,ko03000	-	-	-	CHU_C,CarboxypepD_reg,PKD
DTH2_k127_3824759_2	1185876.BN8_03723	7.214e-160	511.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DTH2_k127_3824759_7	1270196.JCKI01000004_gene1224	9.675e-21	93.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DTH2_k127_3824759_5	1121875.KB907550_gene772	1.796e-56	204.0	COG0500@1|root,COG0500@2|Bacteria,4PM90@976|Bacteroidetes,1IJN7@117743|Flavobacteriia	976|Bacteroidetes	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH2_k127_3824759_3	755732.Fluta_1284	1.985e-143	483.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_3824759_4	755732.Fluta_0907	2.065e-90	324.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_3824759_0	1124780.ANNU01000005_gene2458	0.0	1253.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_3824759_1	883096.HMPREF9699_00130	1.757e-173	547.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia	976|Bacteroidetes	F	reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
DTH2_k127_3824759_6	945713.IALB_3196	2.587e-48	184.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
DTH2_k127_3832408_1	1408433.JHXV01000037_gene2573	2.249e-148	482.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,2PBF0@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_3832408_0	1122621.ATZA01000032_gene3058	4.718e-185	600.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1IPA6@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
DTH2_k127_3832408_2	1408433.JHXV01000009_gene1285	6.222e-29	121.0	COG3637@1|root,COG3637@2|Bacteria,4PJ16@976|Bacteroidetes,1ICQ3@117743|Flavobacteriia,2PBMQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_390119_7	313606.M23134_01414	2.952e-58	217.0	COG0840@1|root,COG2202@1|root,COG2208@1|root,COG0840@2|Bacteria,COG2202@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,HAMP,SpoIIE,TPR_12,TPR_8,Y_Y_Y,dCache_1
DTH2_k127_390119_11	755732.Fluta_0073	4.027e-26	111.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes,1I53B@117743|Flavobacteriia	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
DTH2_k127_390119_4	485917.Phep_4149	3.109e-97	321.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
DTH2_k127_390119_8	755732.Fluta_1033	1.428e-56	199.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1I8WV@117743|Flavobacteriia,2PBTR@246874|Cryomorphaceae	976|Bacteroidetes	H	TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_390119_9	468059.AUHA01000002_gene549	3.214e-53	194.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes,1IT1C@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_390119_3	1313421.JHBV01000005_gene4613	1.478e-107	354.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH2_k127_390119_5	926562.Oweho_2692	6.499e-77	261.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia,2PASN@246874|Cryomorphaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DTH2_k127_390119_10	485918.Cpin_1001	2.061e-33	142.0	COG4782@1|root,COG4782@2|Bacteria,4NS8M@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
DTH2_k127_390119_0	153721.MYP_4272	0.0	1151.0	COG0204@1|root,COG4258@1|root,COG0204@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,47P2T@768503|Cytophagia	976|Bacteroidetes	I	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
DTH2_k127_390119_2	391596.PBAL39_08265	2.036e-183	579.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH2_k127_390119_1	1237149.C900_02195	9.179e-199	631.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_390119_12	1279009.ADICEAN_02159	2.233e-22	104.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
DTH2_k127_390119_13	313606.M23134_03680	3.882e-17	83.0	COG2921@1|root,COG2921@2|Bacteria,4PA5E@976|Bacteroidetes,47SS1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
DTH2_k127_390119_6	574375.BAGA_24120	1.921e-75	263.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,1ZDK2@1386|Bacillus	91061|Bacilli	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
DTH2_k127_390119_14	1120951.AUBG01000002_gene1185	6.743e-08	63.0	29U7Q@1|root,30FHP@2|Bacteria,4NQ1E@976|Bacteroidetes,1I2AD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_390119_15	1279009.ADICEAN_00977	7.517e-06	48.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
DTH2_k127_3908498_17	755732.Fluta_1892	6.018e-59	230.0	COG1520@1|root,COG2312@1|root,COG4386@1|root,COG1520@2|Bacteria,COG2312@2|Bacteria,COG4386@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
DTH2_k127_3908498_4	929556.Solca_0646	6.555e-270	843.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH2_k127_3908498_5	313606.M23134_06289	1.165e-240	766.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_3908498_16	985255.APHJ01000040_gene374	4.219e-61	218.0	COG0300@1|root,COG0300@2|Bacteria,4NEFB@976|Bacteroidetes,1HX0Q@117743|Flavobacteriia,2P5QT@244698|Gillisia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_3908498_29	641524.ADICYQ_2140	2.599e-21	101.0	2DNFQ@1|root,32X9Z@2|Bacteria,4PNNB@976|Bacteroidetes,47YC3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3908498_8	1120951.AUBG01000010_gene2033	2.589e-208	668.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH2_k127_3908498_27	1380600.AUYN01000006_gene429	9.427e-32	129.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH2_k127_3908498_32	1121447.JONL01000001_gene735	1.984e-11	66.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3908498_7	1166018.FAES_1088	1.544e-224	699.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DTH2_k127_3908498_30	886379.AEWI01000010_gene643	6.748e-15	76.0	COG0690@1|root,COG0690@2|Bacteria,4NUSJ@976|Bacteroidetes,2FV3K@200643|Bacteroidia,3XKET@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
DTH2_k127_3908498_12	1408473.JHXO01000006_gene1410	6.357e-81	273.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,2FNJ6@200643|Bacteroidia	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
DTH2_k127_3908498_13	929556.Solca_0419	1.578e-72	246.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1IRUT@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DTH2_k127_3908498_10	1250005.PHEL85_1142	2.871e-111	362.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,1HZJ6@117743|Flavobacteriia,3VVBP@52959|Polaribacter	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DTH2_k127_3908498_24	1313421.JHBV01000027_gene1748	1.033e-43	164.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1IS1J@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DTH2_k127_3908498_23	1121870.AUAA01000004_gene737	7.405e-47	171.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia,3HI6A@358033|Chryseobacterium	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DTH2_k127_3908498_1	762903.Pedsa_2264	0.0	2081.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1INW0@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DTH2_k127_3908498_0	385682.AFSL01000100_gene21	0.0	2226.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,3XJJC@558415|Marinilabiliaceae	976|Bacteroidetes	K	RNA polymerase I subunit A N-terminus	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DTH2_k127_3908498_18	1123037.AUDE01000032_gene2256	9.573e-58	203.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
DTH2_k127_3908498_20	1313421.JHBV01000028_gene1857	5.43e-52	204.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
DTH2_k127_3908498_2	649349.Lbys_0384	0.0	1198.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_3908498_28	1453500.AT05_04480	2.486e-27	133.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,fn3
DTH2_k127_3908498_31	96561.Dole_1154	2.703e-13	78.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,42TI1@68525|delta/epsilon subdivisions,2WQ9N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Ankyrin	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
DTH2_k127_3908498_15	1168034.FH5T_14395	3.159e-63	222.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DTH2_k127_3908498_21	927658.AJUM01000012_gene2698	6.588e-52	196.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,2FSPD@200643|Bacteroidia,3XIQE@558415|Marinilabiliaceae	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH2_k127_3908498_19	313594.PI23P_11742	3.496e-56	201.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia,3VVWY@52959|Polaribacter	976|Bacteroidetes	S	haloacid dehalogenase-like hydrolase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
DTH2_k127_3908498_25	575589.HMPREF0018_00470	1.374e-39	158.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,1S3HE@1236|Gammaproteobacteria,3NKED@468|Moraxellaceae	1236|Gammaproteobacteria	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
DTH2_k127_3908498_6	1121904.ARBP01000016_gene5289	3.571e-227	732.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
DTH2_k127_3908498_26	1122621.ATZA01000054_gene60	4.817e-35	138.0	COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,1IT63@117747|Sphingobacteriia	976|Bacteroidetes	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
DTH2_k127_3908498_11	1453500.AT05_01005	7.038e-84	283.0	COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
DTH2_k127_3908498_22	471854.Dfer_5084	1.269e-50	188.0	COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,47K0P@768503|Cytophagia	976|Bacteroidetes	O	ABC-type transport system involved in cytochrome c biogenesis permease component	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
DTH2_k127_3908498_14	945713.IALB_0215	3.295e-70	243.0	COG2818@1|root,COG2818@2|Bacteria	2|Bacteria	L	DNA-3-methyladenine glycosylase activity	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DTH2_k127_3908498_3	927658.AJUM01000047_gene2906	1.544e-270	841.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,3XKNN@558415|Marinilabiliaceae	976|Bacteroidetes	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
DTH2_k127_3908498_9	204536.SULAZ_0349	1.291e-130	437.0	COG0367@1|root,COG0367@2|Bacteria,2G4Q5@200783|Aquificae	200783|Aquificae	F	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_3957824_15	1408433.JHXV01000002_gene354	6.271e-30	128.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_3,CarboxypepD_reg,Collagen,DUF1929,Glyoxal_oxid_N,Laminin_G_3,NosD,PA14,Phage-tail_3,TIG,fn3
DTH2_k127_3957824_5	1122179.KB890422_gene2260	4.359e-62	235.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Peptidase_M6
DTH2_k127_3957824_6	1341155.FSS13T_21560	1.446e-60	223.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DTH2_k127_3957824_17	1123234.AUKI01000019_gene398	1.375e-19	96.0	28KUE@1|root,2ZAB8@2|Bacteria,4PMSF@976|Bacteroidetes,1IJYN@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3957824_12	1122176.KB903531_gene3128	5.526e-33	138.0	COG3000@1|root,COG3000@2|Bacteria,4NMKR@976|Bacteroidetes,1ISPG@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DTH2_k127_3957824_4	929556.Solca_2015	3.528e-79	278.0	COG3239@1|root,COG3239@2|Bacteria,4NKXX@976|Bacteroidetes,1J080@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_3957824_3	1121875.KB907549_gene1942	5.832e-92	308.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,1HWW1@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
DTH2_k127_3957824_0	926562.Oweho_0991	5.526e-258	837.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1I06M@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
DTH2_k127_3957824_9	1341181.FLJC2902T_11650	1.621e-53	195.0	2E7SX@1|root,30XSY@2|Bacteria,4PBBG@976|Bacteroidetes,1INDA@117743|Flavobacteriia,2NZ5P@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3957824_21	1453505.JASY01000013_gene4303	3.643e-09	66.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4PI2H@976|Bacteroidetes,1IA3E@117743|Flavobacteriia,2NXN5@237|Flavobacterium	976|Bacteroidetes	DZ	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH2_k127_3957824_10	1453500.AT05_04940	1.802e-53	199.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia	976|Bacteroidetes	O	Thiol peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH2_k127_3957824_2	411477.PARMER_03044	4.561e-106	349.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,2FM8U@200643|Bacteroidia,22WI0@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DTH2_k127_3957824_13	1408433.JHXV01000010_gene505	1.009e-31	130.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,1IC47@117743|Flavobacteriia,2PB8G@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
DTH2_k127_3957824_20	866536.Belba_1487	3.384e-12	76.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47KIJ@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
DTH2_k127_3957824_11	1278307.KB907013_gene3605	5.627e-40	161.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,2QHYD@267894|Psychromonadaceae	1236|Gammaproteobacteria	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	fkpA	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
DTH2_k127_3957824_1	926551.KB900715_gene2136	6.191e-116	383.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,1EQ11@1016|Capnocytophaga	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
DTH2_k127_3957824_8	1168289.AJKI01000031_gene925	6.734e-57	201.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,2FN4T@200643|Bacteroidia,3XJBJ@558415|Marinilabiliaceae	976|Bacteroidetes	P	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DTH2_k127_3957824_18	269798.CHU_1702	2.704e-18	88.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes,47R73@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
DTH2_k127_3957824_14	742817.HMPREF9449_01097	8.15e-31	132.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,2FWX8@200643|Bacteroidia,22ZWS@171551|Porphyromonadaceae	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
DTH2_k127_3957824_7	1123057.P872_24790	7.804e-60	210.0	COG4807@1|root,COG4807@2|Bacteria,4NSYM@976|Bacteroidetes,47PTJ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1456)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1456
DTH2_k127_3957824_16	755732.Fluta_2749	7.869e-27	109.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWVS@117743|Flavobacteriia,2PAHG@246874|Cryomorphaceae	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DTH2_k127_3969850_12	755732.Fluta_3615	1.289e-117	390.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia,2PAER@246874|Cryomorphaceae	976|Bacteroidetes	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
DTH2_k127_3969850_14	929562.Emtol_4315	1.368e-115	378.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,47MB5@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
DTH2_k127_3969850_10	886379.AEWI01000146_gene3235	2.177e-124	429.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_3969850_22	888832.HMPREF9420_0647	2.002e-55	202.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,2FNE2@200643|Bacteroidia	976|Bacteroidetes	J	RNA methyltransferase TrmH	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_3969850_33	1408433.JHXV01000033_gene1147	6.304e-17	86.0	2A96H@1|root,30YB5@2|Bacteria,4PC34@976|Bacteroidetes,1IMTJ@117743|Flavobacteriia,2PC4Z@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_3969850_28	926562.Oweho_1037	5.595e-34	135.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_3969850_30	1408433.JHXV01000033_gene1145	8.974e-33	134.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_3969850_0	929556.Solca_2412	0.0	1208.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DTH2_k127_3969850_19	1408473.JHXO01000001_gene2122	8.23e-89	304.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_3969850_21	743722.Sph21_1305	6.639e-59	214.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes,1J13D@117747|Sphingobacteriia	976|Bacteroidetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DTH2_k127_3969850_31	1121896.JMLU01000011_gene1480	2.771e-30	121.0	2E46C@1|root,32Z2A@2|Bacteria,4NV81@976|Bacteroidetes,1I537@117743|Flavobacteriia,2NXAP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3969850_27	929556.Solca_3273	4.822e-34	137.0	2A1N9@1|root,30PWI@2|Bacteria,4NPMN@976|Bacteroidetes,1ISIP@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3969850_17	1237149.C900_04027	6.628e-105	355.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
DTH2_k127_3969850_5	755732.Fluta_1606	2.664e-169	542.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2PA4J@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
DTH2_k127_3969850_32	1121373.KB903644_gene3389	1.09e-28	127.0	COG0526@1|root,COG0526@2|Bacteria,4PIJM@976|Bacteroidetes	976|Bacteroidetes	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3969850_4	714943.Mucpa_6106	1.03e-173	548.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_3969850_9	1121904.ARBP01000007_gene2905	9.894e-126	408.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH2_k127_3969850_23	1168034.FH5T_13680	6.436e-50	191.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3969850_16	714943.Mucpa_6109	1.391e-105	352.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1IP6P@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
DTH2_k127_3969850_18	1121904.ARBP01000007_gene2909	1.461e-97	340.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia	2|Bacteria	S	PFAM von Willebrand factor type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
DTH2_k127_3969850_8	509635.N824_03555	6.293e-128	430.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1IR9Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
DTH2_k127_3969850_25	927658.AJUM01000011_gene1321	1.753e-40	159.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,3XIRK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Bacterial SH3 domain	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH2_k127_3969850_26	1492737.FEM08_21820	1.39e-39	154.0	COG0671@1|root,COG0671@2|Bacteria,4NQ5M@976|Bacteroidetes,1IJ0W@117743|Flavobacteriia,2NW53@237|Flavobacterium	976|Bacteroidetes	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DTH2_k127_3969850_13	172045.KS04_15145	4.224e-117	383.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1HYHP@117743|Flavobacteriia,34R61@308865|Elizabethkingia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
DTH2_k127_3969850_7	1122605.KB893643_gene694	1.962e-136	451.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1IR01@117747|Sphingobacteriia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DTH2_k127_3969850_2	485918.Cpin_1945	1.074e-275	859.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DTH2_k127_3969850_6	714943.Mucpa_6509	6.594e-148	477.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,1IQSA@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
DTH2_k127_3969850_15	755732.Fluta_1216	1.054e-112	389.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_3969850_1	929556.Solca_0395	4.602e-284	894.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DTH2_k127_3969850_29	374847.Kcr_0638	6.005e-33	146.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DTH2_k127_3969850_3	391596.PBAL39_09886	2.342e-275	854.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH2_k127_3969850_24	946077.W5A_04289	1.304e-42	157.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,1I3WW@117743|Flavobacteriia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DTH2_k127_3969850_20	558152.IQ37_11220	2.331e-71	245.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1I1TP@117743|Flavobacteriia,3ZQNN@59732|Chryseobacterium	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DTH2_k127_3969850_11	1124780.ANNU01000062_gene549	6.268e-123	404.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH2_k127_3974315_29	153721.MYP_1243	1.613e-72	247.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
DTH2_k127_3974315_8	714943.Mucpa_1535	8.223e-175	556.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DTH2_k127_3974315_30	1158294.JOMI01000009_gene1199	9.219e-69	236.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,2FR7A@200643|Bacteroidia	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
DTH2_k127_3974315_20	243233.MCA1772	4.559e-126	419.0	COG2244@1|root,COG2244@2|Bacteria,1R512@1224|Proteobacteria,1RZ0F@1236|Gammaproteobacteria,1XE8D@135618|Methylococcales	135618|Methylococcales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_3974315_38	755732.Fluta_0889	3.397e-51	186.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,1IFSR@117743|Flavobacteriia,2PBPT@246874|Cryomorphaceae	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
DTH2_k127_3974315_33	1286632.P278_26090	8.802e-60	219.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1HXYD@117743|Flavobacteriia	976|Bacteroidetes	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_3974315_39	742767.HMPREF9456_01968	3.256e-49	177.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia,22XW8@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
DTH2_k127_3974315_5	153721.MYP_2617	4.533e-199	647.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
DTH2_k127_3974315_26	761193.Runsl_1762	1.149e-93	315.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,47N85@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
DTH2_k127_3974315_2	1286632.P278_24770	1.425e-226	704.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
DTH2_k127_3974315_1	1519464.HY22_01110	1.138e-235	760.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
DTH2_k127_3974315_19	1408433.JHXV01000021_gene1671	2.593e-130	462.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4PPWM@976|Bacteroidetes	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	3.1.3.3	ko:K02660,ko:K07315,ko:K17763,ko:K20971,ko:K21009	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022,ko02035,ko02044,ko03021	-	-	-	CBS,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD_5,HisKA,PAS,PAS_3,PAS_4,PAS_9,STAS,SpoIIE,dCache_1
DTH2_k127_3974315_32	1321778.HMPREF1982_01977	1.23e-64	254.0	COG0457@1|root,COG2199@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,26B8I@186813|unclassified Clostridiales	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,TPR_12,TPR_8
DTH2_k127_3974315_24	755732.Fluta_1284	5.191e-104	368.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_3974315_0	580332.Slit_2861	0.0	1315.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
DTH2_k127_3974315_41	755732.Fluta_1540	7.659e-38	145.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia,2PB44@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
DTH2_k127_3974315_11	700598.Niako_2068	8.55e-154	516.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	2|Bacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug
DTH2_k127_3974315_3	1408433.JHXV01000018_gene3848	2.915e-226	751.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I7ZV@117743|Flavobacteriia,2PAMN@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_3974315_40	1107311.Q767_12185	4.278e-42	157.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,1I2VM@117743|Flavobacteriia,2NWBY@237|Flavobacterium	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
DTH2_k127_3974315_34	929556.Solca_0664	6.258e-59	210.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
DTH2_k127_3974315_45	1237149.C900_05137	1.044e-09	63.0	COG3071@1|root,COG3071@2|Bacteria,4NUU1@976|Bacteroidetes,47RW4@768503|Cytophagia	976|Bacteroidetes	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17,TPR_8
DTH2_k127_3974315_12	1168034.FH5T_08175	4.322e-151	484.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DTH2_k127_3974315_46	153721.MYP_3679	3.113e-09	69.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_3974315_35	1121904.ARBP01000001_gene5704	1.223e-54	207.0	COG3064@1|root,COG3064@2|Bacteria,4NNZ9@976|Bacteroidetes,47RDR@768503|Cytophagia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3974315_21	755732.Fluta_2300	2.062e-117	380.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia,2PA6J@246874|Cryomorphaceae	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DTH2_k127_3974315_23	1379270.AUXF01000004_gene3294	1.602e-114	383.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
DTH2_k127_3974315_6	509635.N824_02835	1.007e-195	615.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DTH2_k127_3974315_14	926562.Oweho_2196	4.95e-145	473.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,1HZZ2@117743|Flavobacteriia,2PA9B@246874|Cryomorphaceae	976|Bacteroidetes	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
DTH2_k127_3974315_17	929556.Solca_3233	6.742e-136	441.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1IP2F@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
DTH2_k127_3974315_16	1150600.ADIARSV_0954	1.23e-139	451.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
DTH2_k127_3974315_15	1121904.ARBP01000003_gene6463	5.923e-143	464.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,47KVU@768503|Cytophagia	976|Bacteroidetes	E	Homoserine dehydrogenase, NAD binding domain	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
DTH2_k127_3974315_18	485918.Cpin_1817	2.948e-131	423.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1IQIJ@117747|Sphingobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
DTH2_k127_3974315_7	485918.Cpin_1818	3.572e-179	569.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1IQWR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DTH2_k127_3974315_13	1150600.ADIARSV_3020	2.641e-150	483.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1IQ0J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_3974315_9	485918.Cpin_1820	9.632e-172	546.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1IP4B@117747|Sphingobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
DTH2_k127_3974315_28	485918.Cpin_1829	9.016e-79	267.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1IT1P@117747|Sphingobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_3974315_25	485918.Cpin_1830	1.014e-97	324.0	COG0106@1|root,COG0454@1|root,COG0106@2|Bacteria,COG0456@2|Bacteria,4NEEX@976|Bacteroidetes,1IW2E@117747|Sphingobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH2_k127_3974315_42	1123234.AUKI01000023_gene2008	3.381e-31	126.0	2CCSR@1|root,32RWC@2|Bacteria,4NUMI@976|Bacteroidetes,1I452@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_3974315_22	485918.Cpin_1831	7.779e-117	380.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,1INX3@117747|Sphingobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH2_k127_3974315_27	485918.Cpin_1832	9.87e-87	290.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1INTS@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
DTH2_k127_3974315_31	1086011.HJ01_00981	4.125e-68	235.0	COG1060@1|root,COG1060@2|Bacteria,4PDXS@976|Bacteroidetes,1ICYV@117743|Flavobacteriia,2NW7K@237|Flavobacterium	976|Bacteroidetes	H	Haem-NO-binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
DTH2_k127_3974315_10	700598.Niako_6193	4.295e-166	555.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1IQ5A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HNOBA,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg
DTH2_k127_3974315_36	880071.Fleli_1574	3.601e-54	198.0	COG3279@1|root,COG3279@2|Bacteria,4NHUZ@976|Bacteroidetes,47PSG@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH2_k127_3974315_43	1121897.AUGO01000005_gene101	1.374e-16	95.0	COG3391@1|root,COG4412@1|root,COG3391@2|Bacteria,COG4412@2|Bacteria,4PMS8@976|Bacteroidetes,1IJYE@117743|Flavobacteriia,2P0PK@237|Flavobacterium	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3974315_37	1089547.KB913013_gene3944	2.374e-51	209.0	COG1874@1|root,COG2911@1|root,COG3209@1|root,COG3656@1|root,COG1874@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3656@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_3974315_44	1107311.Q767_15055	4.414e-11	77.0	COG3391@1|root,COG3391@2|Bacteria,4PPH2@976|Bacteroidetes,1IKMV@117743|Flavobacteriia,2NUGB@237|Flavobacterium	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HYR
DTH2_k127_3974315_4	468059.AUHA01000002_gene1108	4.053e-224	701.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_3976749_0	391596.PBAL39_02307	8.038e-152	492.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,1IP6N@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding Protein	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
DTH2_k127_3976749_4	269798.CHU_2983	2.943e-14	76.0	COG4829@1|root,COG4829@2|Bacteria,4NS7J@976|Bacteroidetes,47RN0@768503|Cytophagia	976|Bacteroidetes	Q	muconolactone delta-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MIase
DTH2_k127_3976749_2	1250006.JHZZ01000001_gene2134	2.321e-84	298.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia,3VW8Q@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_3976749_3	755732.Fluta_0829	1.139e-37	162.0	COG5305@1|root,COG5305@2|Bacteria,4PAK3@976|Bacteroidetes,1IMPV@117743|Flavobacteriia,2PAU3@246874|Cryomorphaceae	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_3976749_1	385682.AFSL01000035_gene2906	6.995e-138	450.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae	976|Bacteroidetes	O	Trypsin	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
DTH2_k127_3979136_0	1107311.Q767_04515	0.0	2122.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,1HYI9@117743|Flavobacteriia,2NSQU@237|Flavobacterium	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
DTH2_k127_3979136_1	1189620.AJXL01000179_gene823	5.388e-210	662.0	COG0654@1|root,COG0654@2|Bacteria,4NEVP@976|Bacteroidetes,1HZDZ@117743|Flavobacteriia,2NT39@237|Flavobacterium	976|Bacteroidetes	CH	monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DTH2_k127_3979136_3	1391647.AVSV01000020_gene2203	1.045e-73	256.0	COG0300@1|root,COG0300@2|Bacteria,1TPN1@1239|Firmicutes,24D6Q@186801|Clostridia,36HBE@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_3979136_2	485918.Cpin_3480	4.824e-107	351.0	28I0D@1|root,2Z857@2|Bacteria,4NFD6@976|Bacteroidetes,1IRJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1826
DTH2_k127_402107_2	926562.Oweho_2008	6.519e-133	432.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia,2PADC@246874|Cryomorphaceae	976|Bacteroidetes	S	Rhodanase C-terminal	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
DTH2_k127_402107_3	1121889.AUDM01000003_gene2299	2.196e-132	431.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia,2NT4H@237|Flavobacterium	976|Bacteroidetes	GM	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_402107_5	755732.Fluta_1974	2.614e-44	173.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_402107_6	755732.Fluta_1974	5.585e-36	148.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_402107_1	1123008.KB905696_gene2890	1.722e-235	737.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,22WDE@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DTH2_k127_402107_4	1123276.KB893245_gene1175	1.177e-90	308.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_402107_0	525373.HMPREF0766_11917	3.797e-253	800.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DTH2_k127_4052882_0	1408813.AYMG01000028_gene2405	0.0	1227.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IX5U@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
DTH2_k127_4052882_1	1150600.ADIARSV_3081	5.275e-204	641.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,1IPEM@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0826 Collagenase and related	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
DTH2_k127_4052882_15	391596.PBAL39_20890	5.662e-30	119.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes,1IUDU@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
DTH2_k127_4052882_17	755732.Fluta_1196	1.157e-12	74.0	COG2030@1|root,COG2030@2|Bacteria,4NUTF@976|Bacteroidetes,1IB9P@117743|Flavobacteriia,2PBY4@246874|Cryomorphaceae	976|Bacteroidetes	I	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
DTH2_k127_4052882_13	926549.KI421517_gene3311	5.547e-62	234.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_4052882_18	1453498.LG45_04900	6.917e-05	55.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2NU0I@237|Flavobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5
DTH2_k127_4052882_9	929556.Solca_1912	1.045e-90	304.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1IRFD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_4052882_16	153721.MYP_951	1.324e-15	87.0	COG0382@1|root,COG0382@2|Bacteria,4P9RC@976|Bacteroidetes,47RXG@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
DTH2_k127_4052882_2	714943.Mucpa_1106	1.646e-193	614.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_4052882_3	946077.W5A_05958	4.17e-182	578.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
DTH2_k127_4052882_5	980584.AFPB01000179_gene3457	2.824e-149	487.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1HXSE@117743|Flavobacteriia,405WS@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH2_k127_4052882_11	1406840.Q763_11280	2.668e-79	269.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1HWU0@117743|Flavobacteriia,2NSPB@237|Flavobacterium	976|Bacteroidetes	EH	Anthranilate synthase subunit II	pabA	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_4052882_7	269798.CHU_3292	4.61e-94	318.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,47KKR@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
DTH2_k127_4052882_8	1406840.Q763_11290	5.347e-91	307.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1HYHC@117743|Flavobacteriia,2NSAT@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
DTH2_k127_4052882_14	1158294.JOMI01000007_gene176	1.151e-59	213.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,2FPJD@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
DTH2_k127_4052882_4	1453498.LG45_04625	1.05e-176	561.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia,2NSMG@237|Flavobacterium	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH2_k127_4052882_10	485918.Cpin_1828	2.237e-79	272.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1IQ26@117747|Sphingobacteriia	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
DTH2_k127_4052882_6	1406840.Q763_11310	4.269e-146	470.0	COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia,2NTMV@237|Flavobacterium	976|Bacteroidetes	E	Cytochrome C4	-	-	-	-	-	-	-	-	-	-	-	-	DAHP_synth_1
DTH2_k127_4052882_12	1121899.Q764_05385	5.438e-64	226.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia,2NS7W@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH2_k127_4054496_0	883080.HMPREF9697_03290	9.845e-227	715.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3JUU3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
DTH2_k127_4054496_6	643867.Ftrac_1924	9.28e-84	302.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NJKM@976|Bacteroidetes,47NZZ@768503|Cytophagia	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_4054496_12	886379.AEWI01000022_gene138	2.427e-23	103.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,2G265@200643|Bacteroidia,3XK2K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_4054496_10	1124780.ANNU01000049_gene2213	4.999e-46	180.0	2AAU0@1|root,33Z6J@2|Bacteria,4P4NV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4054496_4	1168034.FH5T_10690	6.242e-99	327.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,2FNRG@200643|Bacteroidia	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_4054496_3	1408473.JHXO01000010_gene3697	1.774e-115	385.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FNZ2@200643|Bacteroidia	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_4054496_1	1484460.JSWG01000004_gene2661	1.082e-125	416.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_4054496_2	1408473.JHXO01000010_gene3699	1.68e-121	400.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FPA0@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
DTH2_k127_4054496_9	1408433.JHXV01000019_gene1946	6.724e-55	207.0	COG4743@1|root,COG4743@2|Bacteria,4NU7A@976|Bacteroidetes,1I314@117743|Flavobacteriia,2PB9G@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4054496_11	755732.Fluta_0091	3.745e-43	160.0	COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,1I39C@117743|Flavobacteriia,2PB1S@246874|Cryomorphaceae	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DTH2_k127_4054496_8	1453498.LG45_12705	7.698e-75	255.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia,2NTGU@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH2_k127_4054496_7	929556.Solca_0688	1.003e-81	275.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1IPZJ@117747|Sphingobacteriia	976|Bacteroidetes	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
DTH2_k127_4054496_5	929556.Solca_3490	6.437e-99	336.0	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1INVF@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_4054496_13	867902.Ornrh_0971	7.822e-06	48.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1HY4A@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
DTH2_k127_4084485_3	1443665.JACA01000051_gene1996	4.016e-05	55.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1INA7@117743|Flavobacteriia,2YJ4W@290174|Aquimarina	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,MAM,PepSY,Peptidase_M4,Peptidase_M4_C,fn3
DTH2_k127_4084485_2	755732.Fluta_0384	7.283e-74	273.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_4084485_1	926562.Oweho_1341	9.477e-106	359.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
DTH2_k127_4084485_0	1454007.JAUG01000031_gene3153	3.46e-322	1015.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DTH2_k127_4101895_1	945550.VISI1226_00275	8.978e-07	54.0	COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,1SEDC@1236|Gammaproteobacteria,1XXSN@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
DTH2_k127_4101895_0	313606.M23134_02746	7.231e-57	211.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,HAMP,SpoIIE,TPR_12,TPR_8,Y_Y_Y,dCache_1
DTH2_k127_4107895_1	746697.Aeqsu_1094	0.0003313	51.0	COG2356@1|root,COG2931@1|root,COG2356@2|Bacteria,COG2931@2|Bacteria,4PM4Z@976|Bacteroidetes,1I3A1@117743|Flavobacteriia	976|Bacteroidetes	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
DTH2_k127_4107895_0	1121957.ATVL01000013_gene61	5.381e-120	404.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,47XXW@768503|Cytophagia	976|Bacteroidetes	T	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_4134145_7	1121904.ARBP01000002_gene7212	2.539e-68	245.0	COG1705@1|root,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,47WJ6@768503|Cytophagia	976|Bacteroidetes	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	lytG	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,LysM
DTH2_k127_4134145_1	929556.Solca_4296	3.74e-111	385.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1INT0@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
DTH2_k127_4134145_4	1122931.AUAE01000011_gene1716	2.032e-91	314.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,2FQJ2@200643|Bacteroidia,22WP5@171551|Porphyromonadaceae	976|Bacteroidetes	V	Beta-lactamase	nylB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_4134145_2	1123234.AUKI01000006_gene141	1.316e-108	355.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1HXZT@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DTH2_k127_4134145_5	1313421.JHBV01000043_gene3214	2.423e-89	305.0	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes	976|Bacteroidetes	M	Bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
DTH2_k127_4134145_9	468059.AUHA01000002_gene1071	6.625e-64	223.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,1ISBJ@117747|Sphingobacteriia	976|Bacteroidetes	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_4134145_16	153721.MYP_3332	1.848e-05	60.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14,4.2.2.2	ko:K01183,ko:K01728	ko00040,ko00520,ko01100,ko02024,map00040,map00520,map01100,map02024	-	R01206,R02334,R02361,R06240	RC00049,RC00467,RC00705	ko00000,ko00001,ko01000	-	GH18	-	An_peroxidase,Big_5,ChiC,F5_F8_type_C,Flg_new,Glyco_hydro_18,Glyco_hydro_92,Pec_lyase_C,SLH,fn3
DTH2_k127_4134145_0	929556.Solca_2664	0.0	1251.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_4134145_12	929556.Solca_0774	2.006e-31	146.0	COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,IgGFc_binding,PKD,SprB
DTH2_k127_4134145_6	1408433.JHXV01000015_gene1745	1.613e-68	243.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C,DUF4150,PorP_SprF
DTH2_k127_4134145_8	620914.JH621274_gene375	8.502e-65	242.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,2YHUV@290174|Aquimarina	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DTH2_k127_4134145_13	395494.Galf_1844	1.973e-29	120.0	2AGY9@1|root,3176X@2|Bacteria	2|Bacteria	S	Gliding motility-associated protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4134145_10	1408473.JHXO01000006_gene1089	3.071e-61	224.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,2FMM9@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Cytoplasmic, score 8.96	gldB	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4134145_14	1358423.N180_08125	5.315e-10	70.0	2CJVV@1|root,336VZ@2|Bacteria,4NW8G@976|Bacteroidetes,1ITX6@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_4134145_3	755732.Fluta_2271	5.379e-106	350.0	COG0171@1|root,COG0171@2|Bacteria,4NEXG@976|Bacteroidetes,1HYCI@117743|Flavobacteriia,2PAK3@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
DTH2_k127_4134145_15	1033810.HLPCO_001609	1.894e-06	53.0	COG0718@1|root,COG0718@2|Bacteria,2NPUK@2323|unclassified Bacteria	2|Bacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
DTH2_k127_4134145_11	616991.JPOO01000003_gene1395	1.898e-44	167.0	COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,1I26T@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
DTH2_k127_4155775_3	1072685.IX83_04210	7.081e-26	108.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,3T4GZ@506|Alcaligenaceae	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_4155775_1	1123008.KB905694_gene1497	6.463e-115	379.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,2FN5I@200643|Bacteroidia,22VZZ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
DTH2_k127_4155775_0	945713.IALB_2228	5.108e-118	396.0	COG0471@1|root,COG0471@2|Bacteria	2|Bacteria	P	metal ion transport	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
DTH2_k127_4155775_2	1122179.KB890431_gene4239	9.012e-42	155.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH2_k127_4215265_5	926562.Oweho_1917	1.21e-57	205.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,1I33N@117743|Flavobacteriia,2PAUY@246874|Cryomorphaceae	976|Bacteroidetes	CO	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_4215265_3	755732.Fluta_2768	1.404e-93	312.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes,1HXXJ@117743|Flavobacteriia,2PAN1@246874|Cryomorphaceae	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
DTH2_k127_4215265_0	525373.HMPREF0766_11560	1.021e-121	398.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,1IPDS@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
DTH2_k127_4215265_4	411154.GFO_2778	1.089e-66	232.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
DTH2_k127_4215265_6	411154.GFO_3422	1.792e-34	134.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4215265_2	1408433.JHXV01000006_gene2660	1.291e-94	317.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1HXDX@117743|Flavobacteriia,2PAPA@246874|Cryomorphaceae	976|Bacteroidetes	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH2_k127_4215265_7	1500281.JQKZ01000001_gene1119	5.587e-06	58.0	2BJ8S@1|root,32DIE@2|Bacteria,4PPTN@976|Bacteroidetes,1IKTI@117743|Flavobacteriia,3ZSP1@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4215265_1	700598.Niako_0299	1.221e-112	371.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH2_k127_4227534_1	1408433.JHXV01000001_gene666	1.34e-80	282.0	2DKXU@1|root,30TFF@2|Bacteria,4NPBR@976|Bacteroidetes,1I8N7@117743|Flavobacteriia,2PAAX@246874|Cryomorphaceae	976|Bacteroidetes	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
DTH2_k127_4227534_0	926562.Oweho_2679	2.385e-169	544.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2PA9R@246874|Cryomorphaceae	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH2_k127_4271979_0	762903.Pedsa_3685	7.475e-135	434.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,1INMS@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH2_k127_4271979_2	1120951.AUBG01000011_gene2480	1.416e-19	92.0	COG2827@1|root,COG2827@2|Bacteria,4NW73@976|Bacteroidetes,1I614@117743|Flavobacteriia	976|Bacteroidetes	L	excinuclease ABC	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_4271979_1	1168034.FH5T_08385	1.482e-59	224.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_4301848_3	1336803.PHEL49_0490	3.944e-16	83.0	COG0438@1|root,COG0438@2|Bacteria,4PI54@976|Bacteroidetes,1I2FR@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_4301848_1	880071.Fleli_1647	1.1e-63	224.0	COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,47MWP@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	sanA	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
DTH2_k127_4301848_0	869213.JCM21142_339	1.344e-86	293.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,47KWT@768503|Cytophagia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DTH2_k127_4301848_2	926562.Oweho_1648	1.014e-20	93.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia,2PB6J@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
DTH2_k127_4451199_7	153721.MYP_3893	0.0002582	46.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,47PQF@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
DTH2_k127_4451199_2	504472.Slin_4170	2.936e-267	852.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_4451199_0	485917.Phep_2163	0.0	1203.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IVZA@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DTH2_k127_4451199_1	1249997.JHZW01000003_gene3472	0.0	1193.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia,2PH8R@252356|Maribacter	976|Bacteroidetes	O	C-terminal, D2-small domain, of ClpB protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DTH2_k127_4451199_5	700598.Niako_6267	4.438e-35	137.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1IYW1@117747|Sphingobacteriia	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
DTH2_k127_4451199_3	1356852.N008_08225	2.698e-134	463.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_4451199_6	755732.Fluta_3174	5.572e-26	109.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia,2PB69@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATP-dependent Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
DTH2_k127_4451199_4	338966.Ppro_3278	4.142e-62	218.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,43BJA@68525|delta/epsilon subdivisions,2WME6@28221|Deltaproteobacteria,43TIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH2_k127_462486_1	929562.Emtol_3085	2.292e-15	79.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
DTH2_k127_462486_0	755732.Fluta_3902	1.406e-129	431.0	COG0823@1|root,COG2885@1|root,COG3063@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3063@2|Bacteria,4NE6G@976|Bacteroidetes,1INKT@117743|Flavobacteriia,2PA4S@246874|Cryomorphaceae	976|Bacteroidetes	MNU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
DTH2_k127_4678731_9	1347342.BN863_31500	1.945e-43	173.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1HXPD@117743|Flavobacteriia	976|Bacteroidetes	M	probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_4678731_4	929556.Solca_3225	5.282e-128	421.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia	976|Bacteroidetes	EP	PFAM Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DTH2_k127_4678731_8	1243664.CAVL020000052_gene4657	1.427e-63	221.0	COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,1ZFR7@1386|Bacillus	91061|Bacilli	M	COG1247 Sortase and related acyltransferases	ywnH	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
DTH2_k127_4678731_2	742725.HMPREF9450_01021	1.825e-177	563.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia,22U3K@171550|Rikenellaceae	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DTH2_k127_4678731_10	1121904.ARBP01000010_gene2315	8.25e-41	158.0	COG2010@1|root,COG2010@2|Bacteria,4NSUK@976|Bacteroidetes,47R5S@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,SirB
DTH2_k127_4678731_0	929556.Solca_3432	4.597e-315	995.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_4678731_6	1408433.JHXV01000008_gene143	1.516e-122	407.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia,2PBCW@246874|Cryomorphaceae	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_4678731_1	926562.Oweho_2448	3.92e-252	797.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia,2PAGV@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Penicillin binding protein transpeptidase domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DTH2_k127_4678731_5	485917.Phep_2918	7.5e-127	408.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DTH2_k127_4678731_7	929556.Solca_2020	3.966e-122	393.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DTH2_k127_4678731_3	1265756.AWZW01000008_gene1121	2.342e-157	509.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_476662_6	929703.KE386491_gene2977	1.945e-36	142.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,47PTQ@768503|Cytophagia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
DTH2_k127_476662_3	1121931.AUHG01000016_gene982	6.247e-121	403.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,4PKKU@976|Bacteroidetes,1IJC1@117743|Flavobacteriia	976|Bacteroidetes	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
DTH2_k127_476662_5	1123277.KB893179_gene3096	9.676e-42	158.0	COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,47PSM@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
DTH2_k127_476662_4	1227739.Hsw_2912	7.446e-54	196.0	COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,47SXZ@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
DTH2_k127_476662_1	1121904.ARBP01000006_gene4035	1.032e-204	677.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_476662_2	926562.Oweho_3031	4.602e-150	503.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2PBRD@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Peptidase family M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_476662_0	1492737.FEM08_32050	0.0	1268.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	fdsA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
DTH2_k127_4893218_0	1286632.P278_06400	0.0	1067.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DTH2_k127_4893218_19	506534.Rhein_1562	5.291e-29	128.0	COG1835@1|root,COG1835@2|Bacteria,1N5D8@1224|Proteobacteria,1RS5Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_4893218_7	755732.Fluta_1284	2.99e-139	470.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_4893218_6	762903.Pedsa_1133	7.077e-145	465.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1INM8@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DTH2_k127_4893218_8	1123373.ATXI01000008_gene1560	4.604e-139	449.0	COG2605@1|root,COG2605@2|Bacteria,2GIF3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH2_k127_4893218_14	1150600.ADIARSV_1996	1.148e-55	199.0	COG1666@1|root,COG1666@2|Bacteria,4NMBZ@976|Bacteroidetes,1IRSS@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
DTH2_k127_4893218_16	763034.HMPREF9446_02212	7.788e-48	180.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,2FPAB@200643|Bacteroidia,4AN9B@815|Bacteroidaceae	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
DTH2_k127_4893218_2	1313421.JHBV01000024_gene5040	2.145e-186	590.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
DTH2_k127_4893218_4	929556.Solca_0226	2.269e-175	556.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1INW2@117747|Sphingobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DTH2_k127_4893218_10	755732.Fluta_1284	8.693e-111	387.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_4893218_24	644968.DFW101_3674	4.907e-08	63.0	COG0500@1|root,COG2226@2|Bacteria,1QZ7W@1224|Proteobacteria,43CZE@68525|delta/epsilon subdivisions,2WYCC@28221|Deltaproteobacteria,2MCB3@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH2_k127_4893218_21	762903.Pedsa_0723	3.399e-23	116.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,4NZAU@976|Bacteroidetes	976|Bacteroidetes	DZ	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4893218_23	1444711.CCJF01000005_gene546	2.023e-20	107.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta,SBBP
DTH2_k127_4893218_12	307480.IW16_13975	1.68e-78	265.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1I1XF@117743|Flavobacteriia,3ZS7I@59732|Chryseobacterium	976|Bacteroidetes	E	glyoxalase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
DTH2_k127_4893218_15	313606.M23134_08237	4.365e-52	200.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,47V60@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_4893218_25	531844.FIC_01224	5.689e-07	59.0	2FBQG@1|root,343VD@2|Bacteria,4P5SZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4893218_1	929562.Emtol_1163	3.682e-194	612.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
DTH2_k127_4893218_17	1237149.C900_02511	1.238e-41	161.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_4893218_13	927658.AJUM01000037_gene2191	1.652e-69	244.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,2G24N@200643|Bacteroidia,3XJR5@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4893218_26	1123234.AUKI01000014_gene2416	6.976e-06	50.0	2EH3X@1|root,33AVW@2|Bacteria,4NYC0@976|Bacteroidetes,1I6GU@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4893218_20	306281.AJLK01000150_gene1995	1.451e-23	117.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_4893218_5	1453500.AT05_00910	8.065e-166	527.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
DTH2_k127_4893218_9	1122621.ATZA01000018_gene3894	1.335e-119	393.0	COG1052@1|root,COG1052@2|Bacteria,4PKE3@976|Bacteroidetes,1INZ9@117747|Sphingobacteriia	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH2_k127_4893218_3	1121904.ARBP01000004_gene882	3.191e-181	575.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,47NI5@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
DTH2_k127_4893218_11	1250005.PHEL85_0711	2.164e-82	278.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia,3VV2I@52959|Polaribacter	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
DTH2_k127_4893218_18	1408473.JHXO01000005_gene1470	8.048e-35	145.0	COG0697@1|root,COG0697@2|Bacteria,4NIBF@976|Bacteroidetes,2FR06@200643|Bacteroidia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_4964564_6	649349.Lbys_0603	1.004e-15	79.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,47KPD@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DTH2_k127_4964564_1	1408433.JHXV01000036_gene251	1.676e-154	497.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
DTH2_k127_4964564_4	1122621.ATZA01000026_gene2216	4.331e-69	239.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DTH2_k127_4964564_2	1453500.AT05_09010	2.252e-144	464.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
DTH2_k127_4964564_5	1408433.JHXV01000018_gene3846	8.48e-45	170.0	COG2197@1|root,COG2197@2|Bacteria,4NNVV@976|Bacteroidetes,1ICPE@117743|Flavobacteriia,2PBHR@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
DTH2_k127_4964564_3	1353276.JADR01000006_gene1253	1.013e-91	311.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
DTH2_k127_4964564_7	1379698.RBG1_1C00001G1428	2.344e-06	59.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria	2|Bacteria	U	FlgD Ig-like domain	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH
DTH2_k127_4964564_0	1408433.JHXV01000002_gene420	1.761e-265	830.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia,2PAJ8@246874|Cryomorphaceae	976|Bacteroidetes	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
DTH2_k127_5062330_8	1121898.Q766_18445	5.771e-33	135.0	COG2730@1|root,COG2730@2|Bacteria,4NNCY@976|Bacteroidetes,1I8BC@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Cellulase
DTH2_k127_5062330_2	929556.Solca_2015	1.833e-69	248.0	COG3239@1|root,COG3239@2|Bacteria,4NKXX@976|Bacteroidetes,1J080@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_5062330_5	886379.AEWI01000052_gene2670	2.449e-54	205.0	COG0438@1|root,COG0438@2|Bacteria,4NZMT@976|Bacteroidetes,2G1JS@200643|Bacteroidia,3XKI2@558415|Marinilabiliaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
DTH2_k127_5062330_1	32057.KB217478_gene1822	6.491e-111	370.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wgaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
DTH2_k127_5062330_0	1121895.Q765_04450	1.551e-288	893.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia,2NU4U@237|Flavobacterium	976|Bacteroidetes	I	Methylcrotonoyl-CoA carboxylase	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
DTH2_k127_5062330_4	1408433.JHXV01000009_gene1287	3.722e-55	199.0	COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes,1IMRD@117743|Flavobacteriia,2PBNX@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH2_k127_5062330_9	1313421.JHBV01000029_gene1907	1.862e-29	135.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH2_k127_5062330_6	1313421.JHBV01000016_gene5580	2.268e-47	180.0	COG1262@1|root,COG1262@2|Bacteria,4NRGU@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_5062330_3	485918.Cpin_5171	8.771e-66	229.0	COG2824@1|root,COG2824@2|Bacteria,4NEFZ@976|Bacteroidetes,1ITDP@117747|Sphingobacteriia	976|Bacteroidetes	P	PhnA protein	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
DTH2_k127_5062330_7	388413.ALPR1_00435	2.66e-35	136.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia	976|Bacteroidetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DTH2_k127_5083961_30	1392490.JHZX01000001_gene2488	0.0005723	46.0	COG2133@1|root,COG2133@2|Bacteria,4NKFN@976|Bacteroidetes,1HZXK@117743|Flavobacteriia	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5083961_13	1168034.FH5T_11370	1.639e-106	355.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,2FM4R@200643|Bacteroidia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
DTH2_k127_5083961_3	929556.Solca_3928	2.54e-213	670.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1INMC@117747|Sphingobacteriia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DTH2_k127_5083961_8	269798.CHU_1716	1.397e-128	416.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,47K0S@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH2_k127_5083961_26	991.IW20_23050	6.655e-15	76.0	2ERX5@1|root,33JGC@2|Bacteria,4NZ78@976|Bacteroidetes,1IAWT@117743|Flavobacteriia,2NXR8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5083961_20	1123248.KB893326_gene1490	1.716e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_5083961_23	385682.AFSL01000006_gene2376	2.478e-23	106.0	COG0642@1|root,COG2205@2|Bacteria,4NX2D@976|Bacteroidetes,2G28Q@200643|Bacteroidia,3XKD2@558415|Marinilabiliaceae	976|Bacteroidetes	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
DTH2_k127_5083961_27	869213.JCM21142_31015	1.167e-08	66.0	COG4783@1|root,COG4783@2|Bacteria,4PP6D@976|Bacteroidetes	976|Bacteroidetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
DTH2_k127_5083961_6	1408433.JHXV01000015_gene1734	2.173e-137	457.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4P03T@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
DTH2_k127_5083961_5	929556.Solca_1867	3.967e-174	557.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_5083961_11	1408433.JHXV01000026_gene3026	6.192e-107	378.0	COG0419@1|root,COG0823@1|root,COG0419@2|Bacteria,COG0823@2|Bacteria,4P15I@976|Bacteroidetes,1IE72@117743|Flavobacteriia,2PBDD@246874|Cryomorphaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_5083961_18	926562.Oweho_2438	1.343e-61	224.0	2A91X@1|root,30Y5X@2|Bacteria,4PBWY@976|Bacteroidetes,1IMR7@117743|Flavobacteriia,2PBN4@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5083961_16	1408433.JHXV01000009_gene1311	1.087e-71	250.0	COG2230@1|root,COG2230@2|Bacteria,4PKDE@976|Bacteroidetes,1HWWC@117743|Flavobacteriia	976|Bacteroidetes	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
DTH2_k127_5083961_1	1408473.JHXO01000006_gene1179	4.358e-245	781.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,2FN6Z@200643|Bacteroidia	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DTH2_k127_5083961_10	926549.KI421517_gene3662	3.312e-111	366.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,47JSA@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_5083961_24	1237149.C900_04718	7.352e-19	102.0	COG2353@1|root,COG2353@2|Bacteria,4PP17@976|Bacteroidetes,47YSH@768503|Cytophagia	976|Bacteroidetes	G	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5083961_25	153721.MYP_2602	3.57e-17	96.0	COG1572@1|root,COG2931@1|root,COG3227@1|root,COG3266@1|root,COG3291@1|root,COG4447@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_5083961_22	1048983.EL17_00650	7.699e-24	106.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,47R93@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
DTH2_k127_5083961_0	761193.Runsl_2487	0.0	1265.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_5083961_17	468059.AUHA01000005_gene2488	6.25e-70	243.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1IS2N@117747|Sphingobacteriia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DTH2_k127_5083961_2	1121890.AUDO01000009_gene138	2.239e-233	737.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia,2NTC3@237|Flavobacterium	976|Bacteroidetes	PT	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
DTH2_k127_5083961_7	269798.CHU_2867	5.686e-133	431.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47N6X@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_5083961_4	509635.N824_19015	4.184e-199	631.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1IQW8@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_5083961_19	1453500.AT05_07045	1.39e-57	203.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1I1AD@117743|Flavobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DTH2_k127_5083961_12	1347342.BN863_10600	8.949e-107	355.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia	976|Bacteroidetes	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_5083961_29	983544.Lacal_2967	1.61e-06	56.0	2E7SQ@1|root,3327W@2|Bacteria,4NUWY@976|Bacteroidetes,1I5CR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5083961_14	555500.I215_07941	8.942e-102	339.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1HXYS@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH2_k127_5083961_21	926559.JoomaDRAFT_2201	1.572e-44	167.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia	976|Bacteroidetes	F	pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DTH2_k127_5083961_15	1408433.JHXV01000009_gene1349	2.598e-93	320.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IMQG@117743|Flavobacteriia,2PBAV@246874|Cryomorphaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
DTH2_k127_5083961_9	1168034.FH5T_03525	3.665e-113	382.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_5083961_28	1168034.FH5T_03520	2.377e-07	54.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_2	755732.Fluta_0615	2.499e-84	282.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IMPU@117743|Flavobacteriia,2PATN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_4	269797.Mbar_A0317	4.226e-58	204.0	arCOG03001@1|root,arCOG03001@2157|Archaea,2Y6YJ@28890|Euryarchaeota,2NATB@224756|Methanomicrobia	224756|Methanomicrobia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH2_k127_5147798_1	1392490.JHZX01000001_gene835	9.785e-140	454.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia	976|Bacteroidetes	M	glucose-1-phosphate thymidylyltransferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
DTH2_k127_5147798_8	1121373.KB903663_gene1230	1.235e-41	178.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	4.2.2.20,4.2.2.21	ko:K08961	-	-	-	-	ko00000,ko01000	-	-	-	CHU_C,Calx-beta,Lyase_8,Lyase_catalyt,PA14,SdrD_B
DTH2_k127_5147798_5	1313421.JHBV01000046_gene242	4.216e-57	228.0	COG3210@1|root,COG3343@1|root,COG3210@2|Bacteria,COG3343@2|Bacteria,4P1PQ@976|Bacteroidetes	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_3	1313421.JHBV01000042_gene3338	4.927e-82	304.0	COG2885@1|root,COG5010@1|root,COG2885@2|Bacteria,COG5010@2|Bacteria,4NE6G@976|Bacteroidetes,1IS3H@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,TPR_8
DTH2_k127_5147798_6	946077.W5A_00010	4.756e-53	198.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_5147798_16	1202532.FF52_04535	5.078e-19	99.0	COG1361@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
DTH2_k127_5147798_13	236814.IX39_13680	2.289e-27	129.0	COG5295@1|root,COG5295@2|Bacteria,4NTMP@976|Bacteroidetes,1I4NQ@117743|Flavobacteriia,3ZPHH@59732|Chryseobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
DTH2_k127_5147798_17	445961.IW15_13005	4.153e-10	73.0	2ABI4@1|root,310ZB@2|Bacteria,4PFMH@976|Bacteroidetes,1IGDA@117743|Flavobacteriia,3ZQHS@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_11	755732.Fluta_1618	4.272e-28	132.0	COG5295@1|root,COG5295@2|Bacteria,4PI09@976|Bacteroidetes,1IC5M@117743|Flavobacteriia,2PBSJ@246874|Cryomorphaceae	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_15	1353529.M899_2543	1.534e-24	121.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Peptidase_S74
DTH2_k127_5147798_14	755732.Fluta_1618	4.529e-27	129.0	COG5295@1|root,COG5295@2|Bacteria,4PI09@976|Bacteroidetes,1IC5M@117743|Flavobacteriia,2PBSJ@246874|Cryomorphaceae	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_20	1492737.FEM08_22460	2.38e-05	58.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia,2NX0A@237|Flavobacterium	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_5147798_18	862908.BMS_2153	9.521e-08	66.0	COG2911@1|root,COG3210@1|root,COG3420@1|root,COG5295@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,COG5295@2|Bacteria,1NGFP@1224|Proteobacteria,43EIP@68525|delta/epsilon subdivisions,2MUTH@213481|Bdellovibrionales,2X8HE@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	Chaperone of endosialidase	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Peptidase_S74
DTH2_k127_5147798_12	755732.Fluta_1618	1.811e-27	130.0	COG5295@1|root,COG5295@2|Bacteria,4PI09@976|Bacteroidetes,1IC5M@117743|Flavobacteriia,2PBSJ@246874|Cryomorphaceae	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_7	755732.Fluta_2322	1.172e-48	177.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,2PAX5@246874|Cryomorphaceae	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
DTH2_k127_5147798_19	411477.PARMER_00757	6.313e-07	59.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,2FPTR@200643|Bacteroidia,22Y4J@171551|Porphyromonadaceae	976|Bacteroidetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_5147798_10	760192.Halhy_6262	5.333e-35	148.0	2A78Y@1|root,30W5G@2|Bacteria,4NV8P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5147798_9	1229276.DI53_0587	2.273e-37	147.0	COG0791@1|root,COG0791@2|Bacteria,4NQEP@976|Bacteroidetes,1ISR4@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NlpC P60 family	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
DTH2_k127_5147798_0	1121870.AUAA01000045_gene2932	0.0	1063.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,3HHRY@358033|Chryseobacterium	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_5174993_43	1250006.JHZZ01000001_gene1864	4.728e-14	78.0	2E0HI@1|root,32W3C@2|Bacteria,4NQ7D@976|Bacteroidetes,1I349@117743|Flavobacteriia,3VXB8@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5174993_28	504472.Slin_1064	4.116e-41	156.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
DTH2_k127_5174993_24	1279009.ADICEAN_01928	4.469e-44	164.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,47RNG@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH2_k127_5174993_38	1550091.JROE01000002_gene581	2.282e-24	105.0	COG2151@1|root,COG2151@2|Bacteria,4NV07@976|Bacteroidetes,1IU0N@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH2_k127_5174993_14	266748.HY04_04635	1.556e-99	339.0	COG3278@1|root,COG3278@2|Bacteria,4NGGE@976|Bacteroidetes,1IH7Q@117743|Flavobacteriia,3ZT9J@59732|Chryseobacterium	976|Bacteroidetes	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5174993_20	1123248.KB893326_gene1352	4.998e-65	231.0	COG4309@1|root,COG4309@2|Bacteria,4NR74@976|Bacteroidetes,1IT66@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
DTH2_k127_5174993_12	1124780.ANNU01000013_gene3821	1.095e-123	403.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,4NE9M@976|Bacteroidetes,47P55@768503|Cytophagia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
DTH2_k127_5174993_29	313606.M23134_05531	4.133e-41	162.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47JI7@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH2_k127_5174993_22	1124780.ANNU01000006_gene2906	1.371e-46	175.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,47PPH@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
DTH2_k127_5174993_4	929562.Emtol_2379	2.918e-217	689.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,47JXU@768503|Cytophagia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5174993_37	1123248.KB893337_gene2588	4.738e-25	110.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,1ITI1@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
DTH2_k127_5174993_36	558152.IQ37_18975	1.835e-25	111.0	COG3212@1|root,COG3212@2|Bacteria,4P9D8@976|Bacteroidetes,1IEMY@117743|Flavobacteriia,3ZT0W@59732|Chryseobacterium	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
DTH2_k127_5174993_17	307480.IW16_22710	1.585e-82	278.0	COG0500@1|root,COG2226@2|Bacteria,4NJ84@976|Bacteroidetes,1HXEK@117743|Flavobacteriia,3ZP0N@59732|Chryseobacterium	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DTH2_k127_5174993_11	929556.Solca_3634	4.21e-125	406.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methylase involved in ubiquinone menaquinone biosynthesis	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
DTH2_k127_5174993_26	1123248.KB893315_gene3111	9.154e-44	162.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,1IYKS@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DTH2_k127_5174993_46	649349.Lbys_0225	1.271e-09	66.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,47QN2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5174993_44	675635.Psed_4424	2.951e-12	72.0	2DQB3@1|root,335R8@2|Bacteria,2HK3B@201174|Actinobacteria,4E1TI@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5174993_8	926549.KI421517_gene1504	2.747e-150	494.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47JI8@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
DTH2_k127_5174993_45	411476.BACOVA_01093	7.204e-12	77.0	COG0457@1|root,COG0457@2|Bacteria,4NMWW@976|Bacteroidetes,2G2WZ@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974,NB-ARC,Sel1,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
DTH2_k127_5174993_30	1279009.ADICEAN_00106	1.497e-37	143.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia	976|Bacteroidetes	J	PFAM translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DTH2_k127_5174993_18	755732.Fluta_2725	8.275e-66	255.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
DTH2_k127_5174993_40	700598.Niako_6910	7.484e-21	94.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
DTH2_k127_5174993_41	1233951.IO90_02775	1.415e-16	88.0	COG0457@1|root,COG0457@2|Bacteria,4PKS0@976|Bacteroidetes,1IMN6@117743|Flavobacteriia,3HHTF@358033|Chryseobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5174993_3	926562.Oweho_2554	6.459e-227	717.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia,2PAIQ@246874|Cryomorphaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DTH2_k127_5174993_2	929556.Solca_1282	1.389e-244	762.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH2_k127_5174993_1	1150600.ADIARSV_1392	0.0	1008.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH2_k127_5174993_33	1453500.AT05_00780	3.855e-33	138.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1HXZH@117743|Flavobacteriia	976|Bacteroidetes	S	porT protein	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_5174993_5	1336803.PHEL49_2565	2.538e-196	625.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1HXK1@117743|Flavobacteriia,3VVKZ@52959|Polaribacter	976|Bacteroidetes	S	FAD-dependent	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
DTH2_k127_5174993_32	1122179.KB890415_gene1945	1.628e-33	153.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_5174993_0	929556.Solca_2664	0.0	1279.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_5174993_19	1121904.ARBP01000005_gene4745	8.433e-66	235.0	2E074@1|root,32VV1@2|Bacteria,4NTTK@976|Bacteroidetes,47UPG@768503|Cytophagia	976|Bacteroidetes	S	Bacterial toxin 23	-	-	-	-	-	-	-	-	-	-	-	-	Ntox23
DTH2_k127_5174993_31	926559.JoomaDRAFT_2200	7.918e-37	145.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,1I2WH@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
DTH2_k127_5174993_7	762903.Pedsa_0223	4.153e-151	483.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
DTH2_k127_5174993_34	926562.Oweho_2581	1.245e-26	118.0	2BNB7@1|root,32GYU@2|Bacteria,4NQDS@976|Bacteroidetes,1ICNB@117743|Flavobacteriia,2PB7H@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5174993_9	468059.AUHA01000008_gene2751	4.536e-146	479.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1IQUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
DTH2_k127_5174993_13	762903.Pedsa_0221	1.784e-114	381.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DTH2_k127_5174993_6	1408813.AYMG01000014_gene1522	5.832e-154	492.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_5174993_10	929556.Solca_3252	4.317e-130	422.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DTH2_k127_5174993_39	1250006.JHZZ01000001_gene1036	5.015e-21	93.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1I53M@117743|Flavobacteriia,3VWTK@52959|Polaribacter	976|Bacteroidetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DTH2_k127_5174993_35	1358423.N180_13705	1.452e-26	115.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1ISWG@117747|Sphingobacteriia	976|Bacteroidetes	S	acr, cog1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
DTH2_k127_5174993_23	269798.CHU_2412	8.194e-45	168.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
DTH2_k127_5174993_42	1313301.AUGC01000009_gene985	8.31e-16	92.0	COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_5174993_15	1229487.AMYW01000012_gene4270	7.627e-90	326.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2P0KB@237|Flavobacterium	976|Bacteroidetes	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_5174993_16	762903.Pedsa_2967	1.129e-84	289.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_5174993_25	755732.Fluta_1107	4.743e-44	168.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,1I46Q@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transporter ExbD	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
DTH2_k127_5174993_27	755732.Fluta_1108	2.173e-41	160.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1I08G@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transporter ExbD	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
DTH2_k127_5174993_21	471854.Dfer_4058	8.61e-53	196.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHA@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_5174993_47	1356852.N008_19785	9.622e-09	67.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,47NCA@768503|Cytophagia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
DTH2_k127_5185310_0	1313421.JHBV01000019_gene5329	4.395e-13	81.0	COG2132@1|root,COG4935@1|root,COG2132@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,SprB
DTH2_k127_5208514_15	1121373.KB903664_gene2682	5.044e-11	71.0	COG2244@1|root,COG2244@2|Bacteria,4NGVA@976|Bacteroidetes,47PAZ@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_5208514_12	1094466.KQS_09860	3.745e-22	98.0	COG2827@1|root,COG2827@2|Bacteria,4NUKY@976|Bacteroidetes,1II52@117743|Flavobacteriia,2NXVP@237|Flavobacterium	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_5208514_8	1121904.ARBP01000004_gene849	8.359e-61	217.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
DTH2_k127_5208514_10	1168034.FH5T_05150	3.447e-54	204.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia	976|Bacteroidetes	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_5208514_9	926562.Oweho_1029	1.093e-58	220.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,1I8FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5208514_11	926562.Oweho_0373	1.112e-39	153.0	COG0431@1|root,COG0431@2|Bacteria,4NQV9@976|Bacteroidetes	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH2_k127_5208514_4	485918.Cpin_2032	1.303e-91	307.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
DTH2_k127_5208514_3	755732.Fluta_3572	3.277e-122	397.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia,2PAED@246874|Cryomorphaceae	976|Bacteroidetes	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DTH2_k127_5208514_5	1408433.JHXV01000010_gene615	8.303e-90	304.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia,2PAB0@246874|Cryomorphaceae	976|Bacteroidetes	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DTH2_k127_5208514_0	1121104.AQXH01000007_gene487	1.057e-281	872.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IQEH@117747|Sphingobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
DTH2_k127_5208514_7	313606.M23134_02965	6.229e-81	294.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NJKM@976|Bacteroidetes,47NZZ@768503|Cytophagia	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_5208514_2	1121889.AUDM01000015_gene2036	1.695e-132	429.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1HXVU@117743|Flavobacteriia,2NT3Y@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_5208514_14	1392490.JHZX01000001_gene1039	5.49e-19	89.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	3.1.21.3	ko:K01154,ko:K07461	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	GIY-YIG
DTH2_k127_5208514_13	983544.Lacal_1305	8.789e-21	98.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,1I17F@117743|Flavobacteriia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
DTH2_k127_5208514_1	755732.Fluta_3508	4.388e-266	827.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,2PAB9@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DTH2_k127_5208514_6	755732.Fluta_1325	1.4e-89	319.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_5319786_15	746697.Aeqsu_0974	6.247e-07	53.0	2CMH2@1|root,32SES@2|Bacteria,4NSUS@976|Bacteroidetes,1I479@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5319786_18	1313301.AUGC01000006_gene181	0.0004226	45.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_5319786_9	743722.Sph21_0856	4.826e-82	275.0	COG4565@1|root,COG4584@1|root,COG4565@2|Bacteria,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,1IPYU@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_7,rve
DTH2_k127_5319786_4	714943.Mucpa_3384	2.063e-120	391.0	COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,1IP5Q@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM IstB-like ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
DTH2_k127_5319786_14	1144313.PMI10_02180	1.775e-09	61.0	COG1476@1|root,COG1476@2|Bacteria,4NVQ6@976|Bacteroidetes,1I51D@117743|Flavobacteriia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DTH2_k127_5319786_1	1296415.JACC01000006_gene1570	2.147e-128	428.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1HZSJ@117743|Flavobacteriia,2YIRY@290174|Aquimarina	976|Bacteroidetes	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
DTH2_k127_5319786_3	1408473.JHXO01000010_gene3516	6.603e-122	398.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,2FN64@200643|Bacteroidia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
DTH2_k127_5319786_10	468059.AUHA01000003_gene1826	5.191e-44	172.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5319786_0	1120965.AUBV01000013_gene1362	4.647e-226	709.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH2_k127_5319786_11	385682.AFSL01000062_gene1615	3.639e-40	156.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,2FPFD@200643|Bacteroidia,3XJ9A@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
DTH2_k127_5319786_5	926562.Oweho_0344	2.706e-112	380.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,1IKDV@117743|Flavobacteriia,2PAQU@246874|Cryomorphaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
DTH2_k127_5319786_8	926562.Oweho_0718	4.077e-93	318.0	COG1215@1|root,COG1215@2|Bacteria,4NN4F@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_5319786_6	926562.Oweho_0717	2.865e-104	351.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IEBF@117743|Flavobacteriia,2PB0Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
DTH2_k127_5319786_7	929556.Solca_0221	3.905e-102	349.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_5319786_2	153721.MYP_2040	8.267e-125	404.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47XX0@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_5319786_12	485918.Cpin_5956	5.336e-30	128.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
DTH2_k127_5319786_13	1408433.JHXV01000036_gene241	3.812e-22	96.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1I43K@117743|Flavobacteriia,2PB3N@246874|Cryomorphaceae	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_5320478_8	745718.JADT01000011_gene842	1.028e-09	62.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
DTH2_k127_5320478_9	1392490.JHZX01000001_gene1849	1.104e-09	70.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5
DTH2_k127_5320478_11	929562.Emtol_3692	0.0003097	51.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_5320478_5	1237149.C900_00531	3.613e-50	185.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_5320478_3	376686.Fjoh_1549	1.104e-82	278.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia,2NTPY@237|Flavobacterium	976|Bacteroidetes	FJ	tRNA hydroxylase	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
DTH2_k127_5320478_1	1408473.JHXO01000005_gene1442	1.241e-183	585.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
DTH2_k127_5320478_4	435590.BVU_2546	2.204e-77	266.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,2FP2H@200643|Bacteroidia,4AK8G@815|Bacteroidaceae	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
DTH2_k127_5320478_0	504472.Slin_1469	2.524e-189	608.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,47JVG@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
DTH2_k127_5320478_6	504472.Slin_4890	9.958e-33	132.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,47QE4@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_5320478_2	1123276.KB893254_gene3499	2.834e-180	573.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47KCX@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_5320478_10	1406840.Q763_13210	1.056e-07	63.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I02G@117743|Flavobacteriia,2NV5H@237|Flavobacterium	976|Bacteroidetes	O	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
DTH2_k127_5320478_7	1484460.JSWG01000006_gene3028	1.465e-32	139.0	COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3866@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
DTH2_k127_5357748_37	1120951.AUBG01000001_gene922	6.875e-05	55.0	COG3794@1|root,COG3794@2|Bacteria,4NNXS@976|Bacteroidetes,1I3WK@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DTH2_k127_5357748_31	926556.Echvi_1309	1.664e-22	110.0	COG4447@1|root,COG4447@2|Bacteria,4NZ5X@976|Bacteroidetes	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_5357748_20	926562.Oweho_3086	4.836e-55	197.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1I1B5@117743|Flavobacteriia,2PASX@246874|Cryomorphaceae	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
DTH2_k127_5357748_2	755732.Fluta_0753	4.331e-167	529.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia,2PA8U@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DTH2_k127_5357748_6	1538644.KO02_02460	1.54e-92	307.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DTH2_k127_5357748_17	867902.Ornrh_0450	3.572e-61	213.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,1I1GI@117743|Flavobacteriia	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DTH2_k127_5357748_18	391596.PBAL39_08305	3.949e-56	198.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DTH2_k127_5357748_32	1189612.A33Q_0457	2.624e-13	69.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,47SMT@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
DTH2_k127_5357748_28	946077.W5A_08572	1.25e-34	133.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1I3WQ@117743|Flavobacteriia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH2_k127_5357748_1	385682.AFSL01000026_gene663	8.354e-190	602.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia,3XISD@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecY translocase	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DTH2_k127_5357748_19	1237149.C900_01055	4.062e-55	196.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,47PP0@768503|Cytophagia	976|Bacteroidetes	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DTH2_k127_5357748_35	1307761.L21SP2_0894	7.086e-10	61.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
DTH2_k127_5357748_9	929556.Solca_3010	5.012e-82	275.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1IQ9B@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DTH2_k127_5357748_24	1239415.CM001837_gene1710	2.356e-44	163.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia,37F85@326319|Dokdonia	976|Bacteroidetes	J	Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
DTH2_k127_5357748_11	1229276.DI53_2210	2.305e-77	262.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DTH2_k127_5357748_14	743722.Sph21_1729	4.633e-65	224.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1IS0B@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DTH2_k127_5357748_27	1443665.JACA01000023_gene3789	1.641e-36	139.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,1I2TX@117743|Flavobacteriia,2YJUD@290174|Aquimarina	976|Bacteroidetes	J	Ribosomal protein S14p/S29e	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DTH2_k127_5357748_10	468059.AUHA01000002_gene1320	1.423e-80	271.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1IPX4@117747|Sphingobacteriia	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DTH2_k127_5357748_29	1408322.JHYK01000004_gene873	2.258e-31	126.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,27NA1@186928|unclassified Lachnospiraceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DTH2_k127_5357748_16	525373.HMPREF0766_10451	6.482e-63	217.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DTH2_k127_5357748_26	755732.Fluta_0770	2.777e-37	141.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1I2TE@117743|Flavobacteriia,2PAYV@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DTH2_k127_5357748_34	1122621.ATZA01000014_gene3218	1e-10	64.0	COG0255@1|root,COG0255@2|Bacteria,4P9VV@976|Bacteroidetes,1IU24@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DTH2_k127_5357748_12	929556.Solca_3020	8.689e-72	244.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1IRSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DTH2_k127_5357748_4	1408433.JHXV01000034_gene29	7.342e-116	376.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1HXI0@117743|Flavobacteriia,2PAJY@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DTH2_k127_5357748_22	694427.Palpr_2462	8.936e-52	185.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,2FS3J@200643|Bacteroidia,22XWQ@171551|Porphyromonadaceae	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DTH2_k127_5357748_25	1538644.KO02_02350	1.675e-38	145.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1ISXF@117747|Sphingobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DTH2_k127_5357748_3	929556.Solca_3024	1.044e-125	407.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1INT6@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DTH2_k127_5357748_30	908612.HMPREF9720_2538	6.875e-31	123.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,22VE2@171550|Rikenellaceae	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DTH2_k127_5357748_8	1408813.AYMG01000023_gene2131	8.22e-86	288.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,1IRTU@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DTH2_k127_5357748_5	743722.Sph21_1714	2.453e-95	315.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DTH2_k127_5357748_21	1250005.PHEL85_2634	2.252e-52	185.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1I2VK@117743|Flavobacteriia,3VWJ8@52959|Polaribacter	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DTH2_k127_5357748_0	929556.Solca_3034	0.0	1151.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_5357748_13	865938.Weevi_1370	6.724e-69	236.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1HWP7@117743|Flavobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DTH2_k127_5357748_15	1189619.pgond44_12260	1.213e-64	223.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1I18N@117743|Flavobacteriia,4C3PY@83612|Psychroflexus	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DTH2_k127_5357748_7	1235803.C825_02364	7.83e-90	307.0	COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,2FM92@200643|Bacteroidia,22WF5@171551|Porphyromonadaceae	976|Bacteroidetes	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_2
DTH2_k127_5357748_23	1121373.KB903666_gene1277	1.807e-46	185.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes,47S7A@768503|Cytophagia	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_5357748_36	1453500.AT05_07465	1.705e-05	56.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5357748_33	1408433.JHXV01000006_gene2768	1.708e-12	70.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
DTH2_k127_5357924_2	1416760.AYMS01000068_gene610	4.237e-69	243.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia,47H9W@76831|Myroides	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
DTH2_k127_5357924_3	1121129.KB903360_gene3309	2.429e-63	222.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,2FPNN@200643|Bacteroidia,22XY4@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
DTH2_k127_5357924_0	945713.IALB_2776	4.354e-95	319.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.1.1.199	ko:K03438,ko:K13292	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	LGT
DTH2_k127_5357924_1	391603.FBALC1_03172	2.779e-84	287.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,1HXAV@117743|Flavobacteriia	976|Bacteroidetes	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
DTH2_k127_5362928_1	1086011.HJ01_02938	7.663e-115	374.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia,2NT8F@237|Flavobacterium	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_5362928_0	929556.Solca_0293	2.069e-143	479.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5362928_3	153721.MYP_4660	4.523e-42	162.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_5362928_2	1408473.JHXO01000005_gene1515	5.099e-55	196.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,2FQX0@200643|Bacteroidia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DTH2_k127_5362928_4	485917.Phep_0091	3.598e-30	125.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1ISRI@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DTH2_k127_53714_7	714943.Mucpa_6228	2.127e-42	164.0	COG4912@1|root,COG4912@2|Bacteria,4PIP1@976|Bacteroidetes,1IXK7@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DTH2_k127_53714_0	926549.KI421517_gene2470	8.796e-244	774.0	COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,47JBG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH2_k127_53714_3	1313421.JHBV01000041_gene3707	2.035e-192	626.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
DTH2_k127_53714_8	1121373.KB903665_gene2992	2.213e-06	55.0	2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
DTH2_k127_53714_5	929556.Solca_3331	2.823e-125	411.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH2_k127_53714_4	391598.FBBAL38_08105	1.275e-181	577.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
DTH2_k127_53714_2	1408433.JHXV01000027_gene3728	1.328e-196	650.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_53714_6	755732.Fluta_2685	8.183e-102	355.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_53714_1	1453498.LG45_12855	4.882e-235	728.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia,2NTEM@237|Flavobacterium	976|Bacteroidetes	Q	Homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
DTH2_k127_5388913_15	153721.MYP_4360	1.116e-35	145.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,47NDD@768503|Cytophagia	976|Bacteroidetes	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
DTH2_k127_5388913_14	1168289.AJKI01000031_gene1023	3.306e-39	151.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia,3XK37@558415|Marinilabiliaceae	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
DTH2_k127_5388913_12	1349822.NSB1T_10165	7.771e-58	207.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia,22XSI@171551|Porphyromonadaceae	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH2_k127_5388913_0	1168289.AJKI01000035_gene3578	1.426e-304	946.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,2FNBD@200643|Bacteroidia,3XJ69@558415|Marinilabiliaceae	976|Bacteroidetes	L	Ultra-violet resistance protein B	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DTH2_k127_5388913_16	755732.Fluta_2264	1.003e-21	99.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,1IMRK@117743|Flavobacteriia,2PBRK@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_5388913_9	68219.JNXI01000014_gene970	4.648e-86	300.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DTH2_k127_5388913_11	869213.JCM21142_93326	2.894e-69	239.0	COG0110@1|root,COG0110@2|Bacteria,4NMZ2@976|Bacteroidetes,47P7D@768503|Cytophagia	976|Bacteroidetes	S	acetyltransferase, isoleucine patch superfamily	-	-	-	ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
DTH2_k127_5388913_10	1123234.AUKI01000014_gene2451	1.624e-82	287.0	COG0438@1|root,COG0438@2|Bacteria,4NMHA@976|Bacteroidetes,1IIKP@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH2_k127_5388913_1	880071.Fleli_1561	8.778e-199	637.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_5388913_5	1408433.JHXV01000029_gene3116	8.579e-118	386.0	COG0451@1|root,COG0451@2|Bacteria,4NH7Y@976|Bacteroidetes,1I0N9@117743|Flavobacteriia,2PBG0@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_5388913_7	385682.AFSL01000001_gene1997	8.709e-111	368.0	COG0438@1|root,COG0438@2|Bacteria,4NJ1W@976|Bacteroidetes,2FTR3@200643|Bacteroidia,3XK2C@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_5388913_4	485918.Cpin_6574	9.355e-129	419.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
DTH2_k127_5388913_6	694427.Palpr_1191	2.018e-112	375.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,2FSCQ@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_5388913_3	688270.Celal_4168	1.795e-132	430.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia,1F8PP@104264|Cellulophaga	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_5388913_2	929556.Solca_4085	8.777e-194	615.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
DTH2_k127_5388913_8	1237149.C900_02185	1.243e-96	322.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,47JJC@768503|Cytophagia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH2_k127_5388913_13	1150600.ADIARSV_2420	6.055e-54	196.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
DTH2_k127_5388913_17	509635.N824_13975	1.041e-05	48.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IZBA@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_5390880_4	1121904.ARBP01000015_gene208	1.406e-60	216.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,47PYN@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM comF family protein	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
DTH2_k127_5390880_5	1408433.JHXV01000020_gene3501	1.639e-31	136.0	COG4372@1|root,COG4372@2|Bacteria,4PKE4@976|Bacteroidetes,1IKDW@117743|Flavobacteriia,2PBQB@246874|Cryomorphaceae	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5390880_2	649349.Lbys_0765	1.93e-128	420.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
DTH2_k127_5390880_8	1137281.D778_01968	6.521e-07	59.0	2AFKD@1|root,315MB@2|Bacteria,4PJSZ@976|Bacteroidetes,1I6HV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5390880_7	1123057.P872_08740	1.992e-09	66.0	2EHJH@1|root,33BBD@2|Bacteria,4NXG2@976|Bacteroidetes,47SY6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5390880_3	1341181.FLJC2902T_16300	2.252e-65	239.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia,2NUD9@237|Flavobacterium	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH2_k127_5390880_1	1116472.MGMO_109c00050	8.826e-154	494.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XE5B@135618|Methylococcales	1236|Gammaproteobacteria	E	PFAM Aminotransferase, class I	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_5390880_0	1237149.C900_02686	0.0	1204.0	COG1643@1|root,COG1643@2|Bacteria,4NFJ7@976|Bacteroidetes,47KRZ@768503|Cytophagia	976|Bacteroidetes	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
DTH2_k127_539378_2	1203606.HMPREF1526_02048	5.147e-17	81.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,36DTQ@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH2_k127_539378_1	118173.KB235914_gene1462	2.855e-60	228.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
DTH2_k127_539378_0	1233951.IO90_13695	4.726e-91	304.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1HX0C@117743|Flavobacteriia,3HH77@358033|Chryseobacterium	976|Bacteroidetes	E	Lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
DTH2_k127_5441954_0	1122176.KB903537_gene1695	6.914e-129	432.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IWP1@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_5441954_3	761193.Runsl_3244	1.894e-24	111.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,47R92@768503|Cytophagia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DTH2_k127_5441954_1	1406840.Q763_07090	1.598e-116	380.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia,2NTPU@237|Flavobacterium	976|Bacteroidetes	S	Pyrophosphatase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
DTH2_k127_5441954_2	391598.FBBAL38_05330	6.442e-30	133.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
DTH2_k127_5441954_4	1392488.JHZY01000004_gene2449	1.021e-14	83.0	28PIV@1|root,2ZC8P@2|Bacteria,4NGE2@976|Bacteroidetes,1I08D@117743|Flavobacteriia,2XJRZ@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
DTH2_k127_5485169_11	755732.Fluta_2725	3.442e-90	327.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
DTH2_k127_5485169_0	1185876.BN8_02154	8.508e-318	999.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_5485169_12	1356852.N008_00555	3.65e-84	287.0	COG0412@1|root,COG0412@2|Bacteria,4NE8V@976|Bacteroidetes,47KK1@768503|Cytophagia	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
DTH2_k127_5485169_14	929703.KE386491_gene3431	7.458e-60	210.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,47PQ7@768503|Cytophagia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DTH2_k127_5485169_19	1122621.ATZA01000020_gene3983	2.516e-48	175.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1ISJG@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DTH2_k127_5485169_7	626522.GCWU000325_01209	8.691e-106	350.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,1WCQ0@1283313|Alloprevotella	976|Bacteroidetes	J	Ribosomal protein S2	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DTH2_k127_5485169_9	1229276.DI53_2375	7.172e-103	341.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,1IP5Z@117747|Sphingobacteriia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DTH2_k127_5485169_6	1120966.AUBU01000002_gene1914	1.185e-112	368.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,47JC6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DTH2_k127_5485169_8	1122621.ATZA01000019_gene4270	6.491e-104	348.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1IQ9P@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
DTH2_k127_5485169_4	880071.Fleli_1538	5.407e-144	464.0	COG0399@1|root,COG0399@2|Bacteria,4NEIU@976|Bacteroidetes,47JAI@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_5485169_3	1434325.AZQN01000003_gene2597	2.3e-161	514.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,47M91@768503|Cytophagia	976|Bacteroidetes	M	NeuB family	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
DTH2_k127_5485169_15	313606.M23134_02029	4.734e-57	217.0	COG1670@1|root,COG3980@1|root,COG1670@2|Bacteria,COG3980@2|Bacteria,4NJIT@976|Bacteroidetes,47NUI@768503|Cytophagia	976|Bacteroidetes	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_5485169_13	1069080.KB913028_gene372	2.189e-77	265.0	COG1083@1|root,COG1083@2|Bacteria,1UY6H@1239|Firmicutes,4H978@909932|Negativicutes	909932|Negativicutes	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
DTH2_k127_5485169_16	177437.HRM2_36840	1.016e-56	207.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2MIFH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH2_k127_5485169_17	99598.Cal7507_5348	2.652e-55	200.0	COG0118@1|root,COG0118@2|Bacteria,1GJ7N@1117|Cyanobacteria,1HSP5@1161|Nostocales	1117|Cyanobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	-	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_5485169_5	354242.CJJ81176_1333	1.047e-141	459.0	COG0037@1|root,COG0037@2|Bacteria,1MVXT@1224|Proteobacteria,43BTS@68525|delta/epsilon subdivisions,2YMG1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	D	tRNA processing	pseA	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5485169_1	926549.KI421517_gene3882	1.037e-188	595.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,47K8X@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_5485169_2	1121481.AUAS01000006_gene691	2.012e-161	513.0	COG1086@1|root,COG1086@2|Bacteria,4NGN2@976|Bacteroidetes,47MCI@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
DTH2_k127_5485169_21	929556.Solca_3174	2.096e-35	150.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1ITV6@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_5485169_22	1120965.AUBV01000009_gene3100	5.185e-32	135.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,SAM_MT
DTH2_k127_5485169_18	385682.AFSL01000049_gene509	2.768e-49	191.0	COG0438@1|root,COG0438@2|Bacteria,4NPDT@976|Bacteroidetes,2FSPY@200643|Bacteroidia	976|Bacteroidetes	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH2_k127_5485169_23	360104.CCC13826_0523	3.368e-21	106.0	COG0438@1|root,COG0438@2|Bacteria,1MZ28@1224|Proteobacteria,42XHY@68525|delta/epsilon subdivisions,2YRU1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5485169_10	1317122.ATO12_22855	9.605e-99	334.0	COG0037@1|root,COG0037@2|Bacteria,4NIZR@976|Bacteroidetes,1HZ3F@117743|Flavobacteriia,2YJFP@290174|Aquimarina	976|Bacteroidetes	D	LPS biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
DTH2_k127_5522913_0	391603.FBALC1_05438	3.932e-07	61.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Sortilin-Vps10
DTH2_k127_5522913_1	867900.Celly_1398	2.179e-06	59.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia,1F8CE@104264|Cellulophaga	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_5530214_0	929556.Solca_2039	0.0	1068.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
DTH2_k127_5530214_4	1392490.JHZX01000001_gene426	2.086e-66	232.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,1I178@117743|Flavobacteriia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DTH2_k127_5530214_8	1150600.ADIARSV_0337	3.145e-20	91.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1IU0V@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
DTH2_k127_5530214_6	643867.Ftrac_0507	1.152e-52	187.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,47QDB@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
DTH2_k127_5530214_7	1408433.JHXV01000001_gene1045	2.766e-30	132.0	29N3N@1|root,30P01@2|Bacteria,4PGRH@976|Bacteroidetes,1ICQD@117743|Flavobacteriia,2PBQR@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5530214_9	1408433.JHXV01000001_gene1044	1.25e-10	68.0	2AB69@1|root,310KH@2|Bacteria,4PF6A@976|Bacteroidetes,1IFSI@117743|Flavobacteriia,2PC3T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5530214_3	1121895.Q765_07265	3.886e-74	256.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia,2NS6J@237|Flavobacterium	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
DTH2_k127_5530214_10	1123037.AUDE01000006_gene1190	3.18e-05	57.0	COG3291@1|root,COG3866@1|root,COG3291@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
DTH2_k127_5530214_2	700598.Niako_0505	3.348e-121	414.0	COG4447@1|root,COG5492@1|root,COG4447@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,PIG-L,VCBS,WxL
DTH2_k127_5530214_5	1517682.HW49_04380	5.39e-61	217.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,2FKZG@200643|Bacteroidia,22WYD@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
DTH2_k127_5530214_1	1408813.AYMG01000003_gene2872	1.849e-260	808.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1IPCY@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DTH2_k127_5539767_0	118173.KB235914_gene638	5.176e-122	413.0	COG2251@1|root,COG2251@2|Bacteria,1G9N5@1117|Cyanobacteria,1HGVQ@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,DUF2779
DTH2_k127_5539767_1	313606.M23134_03444	3.523e-73	259.0	COG0464@1|root,COG0464@2|Bacteria,4NPXE@976|Bacteroidetes,47NWY@768503|Cytophagia	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
DTH2_k127_5539767_3	1274524.BSONL12_17244	5.968e-12	76.0	COG2304@1|root,COG2304@2|Bacteria,1UZKX@1239|Firmicutes,4HCSC@91061|Bacilli,1ZBWZ@1386|Bacillus	91061|Bacilli	S	protein containing a von Willebrand factor type A (vWA) domain	ywmD	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
DTH2_k127_5539767_5	714943.Mucpa_0597	2.444e-06	58.0	28HEE@1|root,2Z7QU@2|Bacteria,4NDYE@976|Bacteroidetes,1IP5E@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM phage plasmid-related protein TIGR03299	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
DTH2_k127_5539767_2	984262.SGRA_3093	2.281e-28	124.0	COG1192@1|root,COG1192@2|Bacteria,4NGFE@976|Bacteroidetes,1IW93@117747|Sphingobacteriia	976|Bacteroidetes	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DTH2_k127_5543011_3	1356852.N008_14575	1.413e-50	188.0	COG3023@1|root,COG4733@1|root,COG3023@2|Bacteria,COG4733@2|Bacteria,4NN1U@976|Bacteroidetes	976|Bacteroidetes	V	COGs COG3023 Negative regulator of beta-lactamase expression	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CUB
DTH2_k127_5543011_2	1168289.AJKI01000031_gene1129	2.638e-123	403.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,2FNHU@200643|Bacteroidia,3XJA1@558415|Marinilabiliaceae	976|Bacteroidetes	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DTH2_k127_5543011_1	1121957.ATVL01000007_gene2238	1.655e-127	411.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,47JV3@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM AMP nucleosidase	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_5543011_5	1484460.JSWG01000011_gene1672	1.347e-38	149.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia	976|Bacteroidetes	V	Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
DTH2_k127_5543011_9	1124780.ANNU01000038_gene183	4.842e-05	56.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,47XXW@768503|Cytophagia	976|Bacteroidetes	T	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_5543011_10	1041826.FCOL_10225	0.0003394	53.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,2NU61@237|Flavobacterium	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
DTH2_k127_5543011_0	714943.Mucpa_1601	1.86e-143	464.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DTH2_k127_5543011_4	926562.Oweho_1584	5.14e-41	164.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH2_k127_5543011_8	700598.Niako_3236	5.819e-15	81.0	COG4772@1|root,COG4772@2|Bacteria,4PNU9@976|Bacteroidetes,1J0SG@117747|Sphingobacteriia	976|Bacteroidetes	P	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_5543011_6	755732.Fluta_2398	6.779e-29	122.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_5543011_7	485918.Cpin_3756	2.737e-24	105.0	COG2304@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
DTH2_k127_5548704_0	1131812.JQMS01000001_gene2933	1.213e-235	754.0	COG1629@1|root,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,1HXUT@117743|Flavobacteriia,2NTWY@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
DTH2_k127_5548704_1	1131812.JQMS01000001_gene2931	2.093e-79	272.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,1IIXN@117743|Flavobacteriia,2P0GV@237|Flavobacterium	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
DTH2_k127_5558742_14	886379.AEWI01000010_gene610	2.654e-09	68.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,2FM9A@200643|Bacteroidia,3XJ6S@558415|Marinilabiliaceae	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
DTH2_k127_5558742_10	1202532.FF52_07169	1.122e-30	125.0	COG0848@1|root,COG0848@2|Bacteria,4NRG7@976|Bacteroidetes,1I3UT@117743|Flavobacteriia,2NVYS@237|Flavobacterium	976|Bacteroidetes	U	Biopolymer transporter ExbD	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH2_k127_5558742_5	1150600.ADIARSV_0219	5.757e-49	184.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1IQAP@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_5558742_11	1270196.JCKI01000003_gene2250	6.685e-30	129.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_5558742_12	929562.Emtol_2527	1.309e-27	120.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,47NJ0@768503|Cytophagia	976|Bacteroidetes	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
DTH2_k127_5558742_2	485918.Cpin_0714	4.817e-137	446.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,1IQHU@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminopeptidase	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
DTH2_k127_5558742_13	1408433.JHXV01000014_gene3613	5.079e-12	68.0	2EFZ5@1|root,339RB@2|Bacteria,4NXH9@976|Bacteroidetes	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
DTH2_k127_5558742_8	1168034.FH5T_08940	7.194e-33	131.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH2_k127_5558742_3	1408473.JHXO01000001_gene2274	2.309e-116	408.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,2G3G6@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
DTH2_k127_5558742_7	1408433.JHXV01000001_gene733	4.435e-44	183.0	COG3292@1|root,COG3391@1|root,COG3292@2|Bacteria,COG3391@2|Bacteria,4PKMP@976|Bacteroidetes	976|Bacteroidetes	T	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5558742_1	760192.Halhy_1481	2.059e-144	467.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1INTB@117747|Sphingobacteriia	976|Bacteroidetes	S	amidohydrolase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_5558742_9	468059.AUHA01000006_gene2907	8.316e-32	129.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_5558742_0	1408433.JHXV01000010_gene496	6.028e-221	724.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_5558742_4	1123248.KB893337_gene2591	9.163e-105	352.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,1IRMB@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_5558742_15	313596.RB2501_07410	4.2e-05	52.0	28KJI@1|root,2ZA4I@2|Bacteria,4NFR7@976|Bacteroidetes,1I30H@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5558742_6	860228.Ccan_20530	5.395e-46	167.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1HY1G@117743|Flavobacteriia,1EQ86@1016|Capnocytophaga	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
DTH2_k127_579506_25	1121004.ATVC01000016_gene1758	6.714e-11	64.0	COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,2VWX3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
DTH2_k127_579506_26	1123037.AUDE01000021_gene2159	2.125e-07	64.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
DTH2_k127_579506_5	313606.M23134_05335	3.932e-185	607.0	COG1372@1|root,COG4447@1|root,COG5184@1|root,COG5492@1|root,COG1372@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
DTH2_k127_579506_7	1408433.JHXV01000027_gene3728	1.864e-131	457.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_579506_3	926562.Oweho_1053	7.524e-250	784.0	COG1164@1|root,COG1164@2|Bacteria,4NJFW@976|Bacteroidetes,1I88A@117743|Flavobacteriia	976|Bacteroidetes	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
DTH2_k127_579506_16	1406840.Q763_05480	2.463e-58	209.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1I20T@117743|Flavobacteriia,2P071@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
DTH2_k127_579506_14	1305737.JAFX01000001_gene2772	2.292e-85	291.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
DTH2_k127_579506_20	525373.HMPREF0766_11584	3.757e-38	149.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,1IPYA@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_579506_9	1237149.C900_03620	2.049e-114	374.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
DTH2_k127_579506_17	700598.Niako_7021	9.163e-55	196.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,1ISJ5@117747|Sphingobacteriia	976|Bacteroidetes	I	Beta-carotene hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
DTH2_k127_579506_13	755732.Fluta_2685	2.357e-92	328.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_579506_0	1237149.C900_04408	0.0	1836.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
DTH2_k127_579506_2	929556.Solca_2664	1.267e-316	1049.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_579506_15	485918.Cpin_3624	9.735e-69	244.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1IP9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_579506_8	929556.Solca_2370	2.714e-120	409.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IS3H@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_579506_12	1313421.JHBV01000006_gene304	2.688e-96	331.0	COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_579506_22	1454007.JAUG01000041_gene556	1.674e-35	140.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1ISS3@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
DTH2_k127_579506_19	700598.Niako_5915	7.324e-39	148.0	COG5531@1|root,COG5531@2|Bacteria	2|Bacteria	B	SWIB/MDM2 domain	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
DTH2_k127_579506_23	153721.MYP_897	1.11e-30	131.0	2CFX6@1|root,32S2Q@2|Bacteria,4NTW8@976|Bacteroidetes,47VJ9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_579506_24	1123248.KB893315_gene3022	3.043e-30	133.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_579506_1	1453500.AT05_07450	0.0	1022.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
DTH2_k127_579506_21	755732.Fluta_1390	8.559e-38	153.0	COG3291@1|root,COG3405@1|root,COG3291@2|Bacteria,COG3405@2|Bacteria,4NNHP@976|Bacteroidetes,1I21K@117743|Flavobacteriia	976|Bacteroidetes	U	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS,fn3
DTH2_k127_579506_27	1121895.Q765_19785	7.066e-05	54.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2NU0I@237|Flavobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	fpp1	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
DTH2_k127_579506_18	1453500.AT05_09485	1.256e-44	169.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
DTH2_k127_579506_6	929556.Solca_3389	4.314e-167	541.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1INME@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_579506_4	926549.KI421517_gene2903	1.843e-212	680.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
DTH2_k127_579506_11	869213.JCM21142_41607	2.525e-97	329.0	COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,47MMD@768503|Cytophagia	976|Bacteroidetes	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
DTH2_k127_579506_10	411901.BACCAC_01392	2.472e-108	355.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,2FNMT@200643|Bacteroidia,4AKV8@815|Bacteroidaceae	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_6047894_3	1408433.JHXV01000029_gene3073	6.474e-217	724.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
DTH2_k127_6047894_6	1124780.ANNU01000021_gene2999	3.457e-108	361.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,47KIV@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6047894_21	1123248.KB893317_gene4272	6.053e-09	67.0	COG2755@1|root,COG2755@2|Bacteria,4NNAQ@976|Bacteroidetes,1IUNR@117747|Sphingobacteriia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6047894_7	997884.HMPREF1068_02549	1.751e-98	338.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia,4AK8P@815|Bacteroidaceae	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
DTH2_k127_6047894_20	1218108.KB908298_gene3447	4.456e-26	112.0	COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,1I3Z8@117743|Flavobacteriia	976|Bacteroidetes	J	chain release factor	arfB	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
DTH2_k127_6047894_17	1121904.ARBP01000033_gene3182	7.526e-48	189.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448,ko:K02172	ko01501,ko01503,map01501,map01503	M00627,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1
DTH2_k127_6047894_12	153721.MYP_2624	6.401e-68	243.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_6047894_8	153721.MYP_243	4.068e-91	318.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_6047894_4	153721.MYP_2331	1.717e-137	481.0	COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,4PHTU@976|Bacteroidetes,47P4N@768503|Cytophagia	976|Bacteroidetes	E	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6047894_18	1168034.FH5T_02685	1.202e-42	169.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,2FMM1@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
DTH2_k127_6047894_14	1336803.PHEL49_2398	3.167e-58	226.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia,3VVYD@52959|Polaribacter	976|Bacteroidetes	S	Domain of unknown function (DUF4131)	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
DTH2_k127_6047894_1	926562.Oweho_3351	7.228e-274	897.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6047894_15	694427.Palpr_2977	1.432e-53	192.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia,22Y7E@171551|Porphyromonadaceae	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DTH2_k127_6047894_13	886379.AEWI01000023_gene20	1.67e-58	207.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,2FPFU@200643|Bacteroidia,3XJU5@558415|Marinilabiliaceae	976|Bacteroidetes	K	Transcription elongation factor, N-terminal	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DTH2_k127_6047894_9	1408433.JHXV01000020_gene3546	8.023e-91	312.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1I8GR@117743|Flavobacteriia,2PAP2@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_6047894_2	1408433.JHXV01000022_gene3142	1.686e-268	878.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6047894_0	1408433.JHXV01000020_gene3544	2.499e-294	944.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_6047894_11	929562.Emtol_4175	2.012e-77	260.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia	976|Bacteroidetes	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
DTH2_k127_6047894_5	376686.Fjoh_1126	2.513e-135	437.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia,2NSBZ@237|Flavobacterium	976|Bacteroidetes	EF	Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
DTH2_k127_6047894_16	1296416.JACB01000029_gene4104	1.74e-51	189.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1HWZN@117743|Flavobacteriia,2YHTP@290174|Aquimarina	976|Bacteroidetes	J	Ribosomal protein TL5, C-terminal domain	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DTH2_k127_6047894_19	1454007.JAUG01000044_gene607	5.491e-35	143.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1ISAH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
DTH2_k127_6047894_10	755732.Fluta_2090	1.544e-88	327.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_619222_3	1408433.JHXV01000033_gene1155	5.295e-08	57.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_619222_2	1341181.FLJC2902T_32050	1.13e-08	59.0	2BNTT@1|root,32HHI@2|Bacteria,4PDH1@976|Bacteroidetes,1ING4@117743|Flavobacteriia,2NZHK@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_619222_1	1229487.AMYW01000007_gene3199	1.34e-82	282.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia,2NU0D@237|Flavobacterium	976|Bacteroidetes	M	Hydrolase Nlp P60	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
DTH2_k127_619222_0	1506583.JQJY01000003_gene3193	1.806e-168	537.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HX7B@117743|Flavobacteriia,2NU35@237|Flavobacterium	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_6211213_0	929556.Solca_2237	0.0	1149.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1IR7Y@117747|Sphingobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DTH2_k127_6261978_3	1123035.ARLA01000027_gene225	2.69e-06	55.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NJ39@976|Bacteroidetes,1HZRK@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
DTH2_k127_6261978_1	746697.Aeqsu_0429	1.332e-68	236.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
DTH2_k127_6261978_2	755732.Fluta_3635	9.548e-12	78.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes,1ICNQ@117743|Flavobacteriia,2PBCJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6261978_0	929556.Solca_0791	5.43e-200	631.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_6398181_7	1123278.KB893615_gene5179	1.096e-118	396.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
DTH2_k127_6398181_12	515635.Dtur_1289	1.113e-58	223.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
DTH2_k127_6398181_9	1123242.JH636435_gene829	7.635e-74	264.0	COG0520@1|root,COG0520@2|Bacteria,2IXCD@203682|Planctomycetes	203682|Planctomycetes	E	selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_6398181_14	1267211.KI669560_gene2598	1.105e-41	160.0	2EGEP@1|root,33A6N@2|Bacteria,4NXT1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	5.3.3.4	ko:K03464	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R06990	RC01109	ko00000,ko00001,ko00002,ko01000	-	-	-	MIase
DTH2_k127_6398181_6	468059.AUHA01000007_gene2695	1.355e-134	430.0	2CEQ4@1|root,2ZUK4@2|Bacteria,4NPFT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6398181_1	402612.FP1411	1.304e-233	730.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2NSWF@237|Flavobacterium	976|Bacteroidetes	M	Membrane bound O-acyl transferase, MBOAT family protein	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH2_k127_6398181_16	1172562.HCN_0687	2.604e-31	137.0	2E9Y7@1|root,3343V@2|Bacteria,1NA3N@1224|Proteobacteria,42WY9@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6398181_19	313595.P700755_002049	1.813e-07	63.0	2DS77@1|root,33EV1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6398181_5	1341181.FLJC2902T_14610	8.577e-181	568.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,1HZN9@117743|Flavobacteriia,2NV96@237|Flavobacterium	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
DTH2_k127_6398181_10	742767.HMPREF9456_02322	8.529e-69	237.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,2FPT2@200643|Bacteroidia,22YQF@171551|Porphyromonadaceae	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
DTH2_k127_6398181_13	313606.M23134_02803	5.394e-58	205.0	COG3476@1|root,COG3476@2|Bacteria,4NP0D@976|Bacteroidetes,47T79@768503|Cytophagia	976|Bacteroidetes	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
DTH2_k127_6398181_2	869213.JCM21142_72829	2.314e-207	656.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,47JWD@768503|Cytophagia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DTH2_k127_6398181_18	929556.Solca_0341	3.927e-24	108.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1ISU1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6398181_3	1122621.ATZA01000029_gene2778	4.697e-204	644.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1IPIU@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
DTH2_k127_6398181_17	1442598.JABW01000030_gene1346	1.029e-25	114.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,42X8C@68525|delta/epsilon subdivisions,2YRQE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	TIGRFAM nicotinamide mononucleotide transporter PnuC	-	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
DTH2_k127_6398181_15	468059.AUHA01000002_gene672	5.652e-36	144.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1ISIF@117747|Sphingobacteriia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
DTH2_k127_6398181_0	1123278.KB893592_gene5988	2.888e-234	749.0	COG4206@1|root,COG4206@2|Bacteria,4PM93@976|Bacteroidetes,47YB2@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_6398181_11	1121897.AUGO01000016_gene1060	1.164e-68	250.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,2NV0G@237|Flavobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_6398181_4	926562.Oweho_0200	1.676e-192	610.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia,2PAD9@246874|Cryomorphaceae	976|Bacteroidetes	J	Uncharacterized protein family UPF0004	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
DTH2_k127_6398181_8	1124780.ANNU01000037_gene145	4.572e-86	292.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH2_k127_6405295_6	153721.MYP_1998	8.158e-92	308.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
DTH2_k127_6405295_10	746697.Aeqsu_2371	1.605e-52	190.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,1I27H@117743|Flavobacteriia	976|Bacteroidetes	J	acetyltransferase	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
DTH2_k127_6405295_1	926562.Oweho_1011	8.152e-186	601.0	COG0457@1|root,COG3303@1|root,COG0457@2|Bacteria,COG3303@2|Bacteria,4NDTY@976|Bacteroidetes,1HXS9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_2,TPR_8
DTH2_k127_6405295_9	926549.KI421517_gene2929	2.074e-70	250.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,47J93@768503|Cytophagia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
DTH2_k127_6405295_0	755732.Fluta_4067	3.866e-200	633.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2PBCM@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_6405295_4	313598.MED152_12384	1.174e-96	331.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia,3VV44@52959|Polaribacter	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6405295_5	1123234.AUKI01000011_gene1056	3.015e-92	308.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,1HXBY@117743|Flavobacteriia	976|Bacteroidetes	J	Pseudouridine synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
DTH2_k127_6405295_3	1168034.FH5T_20510	8.376e-144	460.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH2_k127_6405295_12	1408813.AYMG01000012_gene970	2.078e-34	137.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1IT87@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin	trxC	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_8
DTH2_k127_6405295_11	1122226.AUHX01000006_gene2110	2.051e-52	194.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_6405295_7	714943.Mucpa_0534	9.565e-80	276.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1IPT7@117747|Sphingobacteriia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
DTH2_k127_6405295_8	1408473.JHXO01000006_gene1097	9.278e-78	273.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia	976|Bacteroidetes	CO	AhpC Tsa family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
DTH2_k127_6405295_2	755732.Fluta_0944	8.277e-146	488.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2PAM4@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
DTH2_k127_6405295_13	1237149.C900_03124	3.141e-22	105.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,47NE3@768503|Cytophagia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
DTH2_k127_6407317_5	1089547.KB913013_gene1555	6.13e-10	66.0	2DM48@1|root,31NG2@2|Bacteria,4NQJF@976|Bacteroidetes,47QMX@768503|Cytophagia	976|Bacteroidetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
DTH2_k127_6407317_1	929556.Solca_3503	6.262e-102	334.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1IQF9@117747|Sphingobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH2_k127_6407317_0	1408473.JHXO01000001_gene2033	3.415e-154	505.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FP0Y@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_6407317_4	1453500.AT05_08785	2.494e-12	72.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Rieske
DTH2_k127_6407317_2	525373.HMPREF0766_11926	2.707e-58	210.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6407317_3	1121904.ARBP01000015_gene247	1.637e-42	160.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia	976|Bacteroidetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH2_k127_6420915_4	755732.Fluta_1670	3.679e-08	65.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,SprB
DTH2_k127_6420915_5	1122226.AUHX01000005_gene2384	2.809e-06	60.0	COG5295@1|root,COG5295@2|Bacteria,4NN7P@976|Bacteroidetes,1I1GH@117743|Flavobacteriia	976|Bacteroidetes	UW	Head domain of trimeric autotransporter adhesin	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	YadA_head
DTH2_k127_6420915_1	1506583.JQJY01000001_gene398	4.592e-23	114.0	COG5295@1|root,COG5295@2|Bacteria,4NR12@976|Bacteroidetes,1IKK1@117743|Flavobacteriia,2P0QJ@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6420915_0	411477.PARMER_03785	4.578e-40	171.0	COG3591@1|root,COG3591@2|Bacteria,4NG2K@976|Bacteroidetes,2FRA2@200643|Bacteroidia,22Z8D@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the peptidase S1B family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
DTH2_k127_6420915_3	1121870.AUAA01000069_gene2596	5.897e-15	76.0	2CMH2@1|root,32SES@2|Bacteria,4NSUS@976|Bacteroidetes,1IM90@117743|Flavobacteriia,3HJ2N@358033|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6439169_20	1121939.L861_22175	3.228e-08	63.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XIIJ@135619|Oceanospirillales	135619|Oceanospirillales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
DTH2_k127_6439169_5	755732.Fluta_1284	5.329e-137	466.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_6439169_0	1296416.JACB01000001_gene3566	0.0	1637.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1HXPM@117743|Flavobacteriia,2YH16@290174|Aquimarina	976|Bacteroidetes	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
DTH2_k127_6439169_13	504472.Slin_0515	1.248e-44	168.0	COG3428@1|root,COG3428@2|Bacteria,4NW40@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
DTH2_k127_6439169_7	755732.Fluta_1284	3.443e-94	333.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_6439169_4	1279009.ADICEAN_03250	5.151e-147	473.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH2_k127_6439169_11	866536.Belba_1264	2.008e-57	206.0	COG2836@1|root,COG2836@2|Bacteria,4PP5N@976|Bacteroidetes	976|Bacteroidetes	S	Biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6439169_10	1341181.FLJC2902T_22700	1.543e-63	238.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
DTH2_k127_6439169_3	1408433.JHXV01000010_gene581	6.354e-155	529.0	COG3023@1|root,COG3227@1|root,COG3291@1|root,COG3023@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,4PI19@976|Bacteroidetes,1IG7F@117743|Flavobacteriia,2PBHU@246874|Cryomorphaceae	976|Bacteroidetes	E	Fungalysin/Thermolysin Propeptide Motif	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
DTH2_k127_6439169_2	1408433.JHXV01000010_gene581	6.885e-159	543.0	COG3023@1|root,COG3227@1|root,COG3291@1|root,COG3023@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,4PI19@976|Bacteroidetes,1IG7F@117743|Flavobacteriia,2PBHU@246874|Cryomorphaceae	976|Bacteroidetes	E	Fungalysin/Thermolysin Propeptide Motif	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
DTH2_k127_6439169_9	1121012.AUKX01000005_gene3695	1.139e-74	271.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia,23GF1@178469|Arenibacter	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_6439169_12	883096.HMPREF9699_00932	1.663e-48	180.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,1I1DQ@117743|Flavobacteriia	976|Bacteroidetes	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
DTH2_k127_6439169_17	762903.Pedsa_0259	1.088e-32	138.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH2_k127_6439169_6	1347342.BN863_22540	6.73e-114	389.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1HY4X@117743|Flavobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH2_k127_6439169_15	509635.N824_02895	2.895e-39	148.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ITGS@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DTH2_k127_6439169_1	391587.KAOT1_09781	0.0	1063.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_6439169_16	755732.Fluta_0942	2.762e-38	152.0	2BBSK@1|root,32XPV@2|Bacteria,4NSW3@976|Bacteroidetes,1IKDA@117743|Flavobacteriia,2PB42@246874|Cryomorphaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_6439169_18	1121897.AUGO01000007_gene311	2.309e-21	98.0	2DMKZ@1|root,32SAQ@2|Bacteria,4NS7K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MpPF26
DTH2_k127_6439169_19	1453505.JASY01000011_gene4119	9.153e-16	93.0	COG3291@1|root,COG3291@2|Bacteria,4NIED@976|Bacteroidetes,1I093@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6439169_8	984262.SGRA_3314	2.581e-82	311.0	COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes	976|Bacteroidetes	S	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6439169_14	880073.Calab_0995	5.108e-43	160.0	COG0501@1|root,COG0501@2|Bacteria,2NS4G@2323|unclassified Bacteria	2|Bacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH2_k127_6439397_7	946077.W5A_03919	7.188e-10	60.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1HYB1@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase, M22	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_6439397_3	761193.Runsl_5534	1.172e-98	326.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH2_k127_6439397_2	1094980.Mpsy_0782	8.163e-111	368.0	COG0598@1|root,arCOG02265@2157|Archaea,2XTRP@28890|Euryarchaeota,2N9K8@224756|Methanomicrobia	224756|Methanomicrobia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DTH2_k127_6439397_1	1453498.LG45_11060	7.997e-143	462.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1HXXZ@117743|Flavobacteriia,2NS9U@237|Flavobacterium	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
DTH2_k127_6439397_4	925409.KI911562_gene283	4.812e-34	142.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1IT51@117747|Sphingobacteriia	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_6439397_5	926559.JoomaDRAFT_0170	7.351e-34	135.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH2_k127_6439397_6	1121373.KB903654_gene1688	4.472e-10	65.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
DTH2_k127_6439397_0	929556.Solca_1389	4.167e-276	868.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_6445209_12	1123057.P872_23980	6.473e-08	55.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia	976|Bacteroidetes	S	beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
DTH2_k127_6445209_6	485918.Cpin_4995	1.931e-60	214.0	COG1187@1|root,COG1187@2|Bacteria,4NM4U@976|Bacteroidetes,1IY6P@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH2_k127_6445209_4	1408433.JHXV01000011_gene2012	2.578e-122	404.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1HY3M@117743|Flavobacteriia,2PAJZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
DTH2_k127_6445209_0	391596.PBAL39_06026	3.899e-320	994.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
DTH2_k127_6445209_10	1033740.CAEW01000034_gene1628	5.442e-15	83.0	COG2230@1|root,COG2230@2|Bacteria,1V4JG@1239|Firmicutes,4HH18@91061|Bacilli,26F57@186818|Planococcaceae	91061|Bacilli	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,DOT1,Methyltransf_32
DTH2_k127_6445209_3	926562.Oweho_0378	1.876e-122	417.0	COG2885@1|root,COG3063@1|root,COG2885@2|Bacteria,COG3063@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PA4T@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
DTH2_k127_6445209_1	1492737.FEM08_04220	9.648e-167	538.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
DTH2_k127_6445209_2	1492737.FEM08_04220	7.672e-148	483.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
DTH2_k127_6445209_7	880071.Fleli_3148	6.514e-55	205.0	COG4324@1|root,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia	976|Bacteroidetes	I	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
DTH2_k127_6445209_8	714943.Mucpa_4498	2.284e-48	182.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,1ITFE@117747|Sphingobacteriia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_6445209_5	1408813.AYMG01000010_gene283	1.038e-109	368.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
DTH2_k127_6445209_9	269798.CHU_2678	2.043e-18	87.0	COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,47RWN@768503|Cytophagia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
DTH2_k127_6445209_11	1408433.JHXV01000015_gene1768	2.486e-09	64.0	2A94C@1|root,30Y8F@2|Bacteria,4PBZT@976|Bacteroidetes,1ICRM@117743|Flavobacteriia,2PBWN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6448739_2	742766.HMPREF9455_01166	1.796e-100	329.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,2FMNU@200643|Bacteroidia,22WPR@171551|Porphyromonadaceae	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_6448739_3	391598.FBBAL38_07265	1.284e-73	256.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,1HXF6@117743|Flavobacteriia	976|Bacteroidetes	S	Alpha beta hydrolase	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH2_k127_6448739_7	755732.Fluta_1297	2.694e-51	188.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1I176@117743|Flavobacteriia,2PB75@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH2_k127_6448739_0	1313421.JHBV01000012_gene4088	3.266e-188	605.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,Trp_halogenase
DTH2_k127_6448739_6	471854.Dfer_5798	2.768e-53	190.0	2CE7N@1|root,30Q80@2|Bacteria,4NNKP@976|Bacteroidetes,47RMH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6448739_1	471854.Dfer_5799	8.423e-150	480.0	COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,47KBX@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
DTH2_k127_6448739_8	468059.AUHA01000002_gene1129	3.558e-11	74.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6448739_5	1267211.KI669560_gene721	1.872e-53	189.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,1ISNQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DTH2_k127_6448739_4	1123248.KB893322_gene626	2.794e-66	234.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DTH2_k127_6466679_4	762903.Pedsa_0463	1.261e-05	54.0	COG3266@1|root,COG4677@1|root,COG4886@1|root,COG3266@2|Bacteria,COG4677@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	pemA	GO:0005575,GO:0005576	3.1.1.11,3.4.24.25,3.4.24.26	ko:K01051,ko:K01399,ko:K08604,ko:K10297,ko:K15125	ko00040,ko01100,ko01503,ko02024,ko05110,ko05111,ko05133,map00040,map01100,map01503,map02024,map05110,map05111,map05133	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko00536,ko01000,ko01002,ko04121	-	-	-	Beta_helix,Pectinesterase
DTH2_k127_6466679_1	746697.Aeqsu_0488	1.414e-155	507.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH2_k127_6466679_0	929556.Solca_1166	1.64e-233	729.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1IQ95@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase, family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_6466679_2	1123276.KB893252_gene3779	1.35e-11	72.0	COG1595@1|root,COG1595@2|Bacteria,4NN2T@976|Bacteroidetes,47P7Q@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_6494217_2	755732.Fluta_3106	4.698e-36	143.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6494217_1	755732.Fluta_3105	1.568e-55	209.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_6494217_0	755732.Fluta_3104	3.239e-65	233.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	2|Bacteria	S	C-terminal domain of CHU protein family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_6499014_54	525373.HMPREF0766_10007	8.62e-55	197.0	292K5@1|root,2ZQ43@2|Bacteria,4NPMT@976|Bacteroidetes,1IYQ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6499014_48	269798.CHU_0459	3.822e-67	246.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,4P3T9@976|Bacteroidetes,47V03@768503|Cytophagia	976|Bacteroidetes	S	Leucine-rich repeats, outliers	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_6499014_74	1122176.KB903532_gene2671	6.476e-08	65.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DTH2_k127_6499014_56	929556.Solca_3593	2.643e-51	190.0	2F1U9@1|root,33UU9@2|Bacteria,4P2VQ@976|Bacteroidetes,1IXGS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6499014_6	700598.Niako_6302	4.879e-214	678.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,1INVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
DTH2_k127_6499014_28	313606.M23134_05446	4.42e-114	376.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_6499014_40	1121104.AQXH01000001_gene1147	5.397e-74	255.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
DTH2_k127_6499014_24	755732.Fluta_1927	9.261e-124	403.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
DTH2_k127_6499014_49	1121899.Q764_02025	9.61e-66	233.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1HY0U@117743|Flavobacteriia,2NT6Y@237|Flavobacterium	976|Bacteroidetes	I	Alpha beta hydrolase	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH2_k127_6499014_26	153721.MYP_4404	7.434e-117	380.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
DTH2_k127_6499014_16	1122176.KB903568_gene3468	1.49e-172	571.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,1IPK5@117747|Sphingobacteriia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_6499014_10	153721.MYP_4273	4.26e-191	608.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,47K5X@768503|Cytophagia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_6499014_41	1237149.C900_03516	1.201e-73	263.0	COG3509@1|root,COG4733@1|root,COG3509@2|Bacteria,COG4733@2|Bacteria,4NR4C@976|Bacteroidetes	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
DTH2_k127_6499014_32	755732.Fluta_0357	2.318e-108	366.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
DTH2_k127_6499014_72	1408433.JHXV01000041_gene3578	3.055e-12	72.0	2A94W@1|root,30Y96@2|Bacteria,4PC0G@976|Bacteroidetes,1ICSA@117743|Flavobacteriia,2PBZB@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6499014_5	1408473.JHXO01000010_gene3593	2.157e-233	732.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia	976|Bacteroidetes	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH2_k127_6499014_71	158190.SpiGrapes_0899	2.095e-13	78.0	COG2068@1|root,COG2068@2|Bacteria,2J9CR@203691|Spirochaetes	203691|Spirochaetes	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
DTH2_k127_6499014_61	457415.HMPREF1006_02239	8.682e-46	176.0	COG1975@1|root,COG1975@2|Bacteria,3TAJF@508458|Synergistetes	508458|Synergistetes	O	maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
DTH2_k127_6499014_59	865861.AZSU01000001_gene549	4.419e-47	195.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,36IEF@31979|Clostridiaceae	186801|Clostridia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DTH2_k127_6499014_11	767817.Desgi_0419	9.827e-190	626.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DTH2_k127_6499014_57	485913.Krac_2435	1.721e-47	182.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
DTH2_k127_6499014_73	903818.KI912268_gene2338	2.97e-08	62.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
DTH2_k127_6499014_52	1007105.PT7_2041	1.944e-57	209.0	COG1073@1|root,COG1073@2|Bacteria,1NX86@1224|Proteobacteria,2WGJF@28216|Betaproteobacteria,3T1VE@506|Alcaligenaceae	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
DTH2_k127_6499014_39	706587.Desti_1480	5.904e-77	265.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_6499014_19	1187851.A33M_3194	2.951e-160	512.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_6499014_30	1232410.KI421412_gene166	5.265e-111	368.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH2_k127_6499014_23	1168065.DOK_00285	8.136e-129	424.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1J4HU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_6499014_64	585501.HMPREF6123_1940	2.806e-41	173.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,2PR95@265975|Oribacterium	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DTH2_k127_6499014_60	1125863.JAFN01000001_gene583	1.22e-46	189.0	COG1893@1|root,COG1893@2|Bacteria,1R96Z@1224|Proteobacteria,42PU0@68525|delta/epsilon subdivisions,2WK47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DTH2_k127_6499014_20	1232410.KI421423_gene1871	4.033e-145	470.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria,43UG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
DTH2_k127_6499014_42	406817.XNC1_2156	1.702e-73	269.0	COG1022@1|root,COG3321@1|root,COG1022@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
DTH2_k127_6499014_37	316057.RPD_1535	5.432e-82	281.0	COG1924@1|root,COG1924@2|Bacteria,1MY0N@1224|Proteobacteria,2U4V9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
DTH2_k127_6499014_22	1237149.C900_04255	1.115e-131	431.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47N5F@768503|Cytophagia	976|Bacteroidetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DTH2_k127_6499014_29	316055.RPE_0606	6.701e-112	377.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
DTH2_k127_6499014_15	316056.RPC_1028	4.033e-176	561.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
DTH2_k127_6499014_31	1244869.H261_03138	5.704e-110	368.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
DTH2_k127_6499014_44	1174504.AJTN02000023_gene4668	1.303e-71	249.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1ZBHS@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG10	-	1.1.1.100,1.3.1.28	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	M00083,M00572	R01505,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00534	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
DTH2_k127_6499014_46	1341155.FSS13T_08510	5.878e-71	264.0	COG3920@1|root,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia,2NVMV@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,TPR_12,TPR_8
DTH2_k127_6499014_1	1341181.FLJC2902T_05490	4.116e-290	903.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1HX75@117743|Flavobacteriia,2NTDV@237|Flavobacterium	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
DTH2_k127_6499014_12	926562.Oweho_2197	6.031e-182	601.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_6499014_3	1122605.KB893635_gene3529	5.592e-245	765.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_6499014_13	929562.Emtol_4231	1.225e-179	572.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,47MVE@768503|Cytophagia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DTH2_k127_6499014_14	755732.Fluta_3921	6.611e-178	566.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1HXRK@117743|Flavobacteriia,2PA9K@246874|Cryomorphaceae	976|Bacteroidetes	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
DTH2_k127_6499014_18	755732.Fluta_3922	2.725e-168	531.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1HXPZ@117743|Flavobacteriia,2PAH5@246874|Cryomorphaceae	976|Bacteroidetes	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH2_k127_6499014_33	755732.Fluta_3923	6.29e-100	330.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1I1FV@117743|Flavobacteriia,2PB6M@246874|Cryomorphaceae	976|Bacteroidetes	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH2_k127_6499014_17	1450525.JATV01000003_gene1751	3.282e-172	547.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1HXJC@117743|Flavobacteriia,2NSFM@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.49	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01287,R01288,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH2_k127_6499014_63	1121904.ARBP01000001_gene5611	1.158e-42	160.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,47R4T@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
DTH2_k127_6499014_21	926549.KI421517_gene819	1.778e-144	473.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,47YJA@768503|Cytophagia	976|Bacteroidetes	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
DTH2_k127_6499014_35	468059.AUHA01000008_gene2781	4.802e-88	297.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1IRUZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobA	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
DTH2_k127_6499014_2	509635.N824_18285	3.222e-268	843.0	COG0155@1|root,COG1895@1|root,COG0155@2|Bacteria,COG1895@2|Bacteria,4NENW@976|Bacteroidetes,1INY4@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitrite and sulphite reductase 4Fe-4S	cysI	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr,TusA
DTH2_k127_6499014_55	755732.Fluta_3928	1.964e-53	192.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1I1Z9@117743|Flavobacteriia,2PAY4@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM Rrf2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH2_k127_6499014_36	485918.Cpin_0426	4.117e-87	290.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1IS18@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_6499014_25	929556.Solca_2939	3.722e-121	394.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1IPZH@117747|Sphingobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
DTH2_k127_6499014_62	1279009.ADICEAN_00944	5.425e-44	175.0	2CB8G@1|root,2Z88H@2|Bacteria,4NF68@976|Bacteroidetes,47M04@768503|Cytophagia	976|Bacteroidetes	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
DTH2_k127_6499014_70	755732.Fluta_3996	1.656e-20	96.0	2E5CT@1|root,3304V@2|Bacteria,4NUT2@976|Bacteroidetes,1II8Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6499014_0	1121129.KB903359_gene2402	0.0	1069.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,2FNQK@200643|Bacteroidia,22X3D@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
DTH2_k127_6499014_45	398720.MED217_13109	1.633e-71	275.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NIFD@976|Bacteroidetes,1I1QH@117743|Flavobacteriia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
DTH2_k127_6499014_53	391598.FBBAL38_10117	2.145e-55	209.0	COG3266@1|root,COG3266@2|Bacteria,4NKYH@976|Bacteroidetes,1I2JU@117743|Flavobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6499014_4	1121895.Q765_08395	2.013e-238	755.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1HX6P@117743|Flavobacteriia,2NS9Q@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_6499014_58	1348583.ATLH01000029_gene1593	3.366e-47	177.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1HXI2@117743|Flavobacteriia,1F7WT@104264|Cellulophaga	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DTH2_k127_6499014_7	643867.Ftrac_3623	2.627e-208	677.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_6499014_38	1492737.FEM08_20530	2.489e-79	278.0	COG1357@1|root,COG3656@1|root,COG1357@2|Bacteria,COG3656@2|Bacteria,4PNNZ@976|Bacteroidetes,1I4RS@117743|Flavobacteriia,2P0TF@237|Flavobacterium	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
DTH2_k127_6499014_8	1121481.AUAS01000008_gene3122	8.418e-203	645.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH2_k127_6499014_27	1122176.KB903598_gene4712	8.126e-116	400.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
DTH2_k127_6499014_68	1348583.ATLH01000029_gene1816	1.308e-37	145.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1I2W7@117743|Flavobacteriia,1F9D7@104264|Cellulophaga	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
DTH2_k127_6499014_9	1120965.AUBV01000003_gene325	4.908e-192	606.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,47JAB@768503|Cytophagia	976|Bacteroidetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DTH2_k127_6499014_65	929556.Solca_1233	4.032e-41	153.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1IT8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DTH2_k127_6499014_67	1168034.FH5T_11030	1.443e-38	149.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,2FTJ4@200643|Bacteroidia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
DTH2_k127_6499014_47	1237149.C900_01012	3.591e-69	239.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,47M4J@768503|Cytophagia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
DTH2_k127_6499014_66	755732.Fluta_3514	9.978e-40	153.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,1I1XW@117743|Flavobacteriia,2PB06@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6499014_43	313606.M23134_04812	4.051e-73	258.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
DTH2_k127_6499014_34	1122176.KB903537_gene1644	9.57e-99	332.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IQN9@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DTH2_k127_6499014_51	1227739.Hsw_1905	1.271e-61	222.0	COG0300@1|root,COG0300@2|Bacteria,4NEKV@976|Bacteroidetes,47NJG@768503|Cytophagia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_6499014_50	755732.Fluta_2899	1.066e-63	244.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_6511138_9	367737.Abu_1280	9.17e-114	382.0	COG1020@1|root,COG1020@2|Bacteria,1R7KS@1224|Proteobacteria,42ZU1@68525|delta/epsilon subdivisions,2YTM6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	AMP-binding enzyme	-	-	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	AMP-binding
DTH2_k127_6511138_15	1442598.JABW01000010_gene191	9.052e-74	262.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2YN3N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Alginate O-acetylation protein	-	-	-	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
DTH2_k127_6511138_23	243265.plu4382	1.3e-17	95.0	COG3966@1|root,COG3966@2|Bacteria,1R8SI@1224|Proteobacteria,1RZMA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	DltD protein	dltD	-	-	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	DltD
DTH2_k127_6511138_26	426716.JOAJ01000006_gene5182	8.419e-05	48.0	2BHWJ@1|root,32C0I@2|Bacteria,2IT5X@201174|Actinobacteria,4G3E8@85025|Nocardiaceae	201174|Actinobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH2_k127_6511138_3	313606.M23134_00438	4.572e-237	740.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH2_k127_6511138_0	926562.Oweho_1923	1.105e-313	968.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia,2PAMC@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DTH2_k127_6511138_12	1453500.AT05_11625	6.776e-96	324.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
DTH2_k127_6511138_8	1408433.JHXV01000014_gene3655	3.772e-117	389.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia,2PAAV@246874|Cryomorphaceae	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6511138_18	471854.Dfer_3473	2.386e-39	154.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,47PEX@768503|Cytophagia	976|Bacteroidetes	C	PFAM Cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH2_k127_6511138_17	1218108.KB908295_gene1811	7.629e-58	206.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
DTH2_k127_6511138_4	1453500.AT05_11605	1.305e-228	715.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH2_k127_6511138_1	926549.KI421517_gene1908	4.666e-307	975.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
DTH2_k127_6511138_11	926562.Oweho_1930	7.346e-99	337.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1I8RP@117743|Flavobacteriia,2PAPE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
DTH2_k127_6511138_6	700598.Niako_6245	1.269e-150	482.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DTH2_k127_6511138_13	385682.AFSL01000096_gene594	6.813e-93	317.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,2FMX9@200643|Bacteroidia,3XIXK@558415|Marinilabiliaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
DTH2_k127_6511138_25	1168289.AJKI01000002_gene2600	2.169e-05	55.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,2FVYZ@200643|Bacteroidia,3XJJ8@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
DTH2_k127_6511138_16	1121373.KB903642_gene3696	2.483e-73	258.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6511138_21	761193.Runsl_5183	5.115e-38	149.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_6511138_10	1313421.JHBV01000027_gene1717	3.046e-112	372.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1IPZD@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DTH2_k127_6511138_20	709991.Odosp_0222	3.994e-38	145.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,2FTUV@200643|Bacteroidia,22YCW@171551|Porphyromonadaceae	976|Bacteroidetes	L	Belongs to the bacterial histone-like protein family	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_6511138_22	1150600.ADIARSV_2095	3.404e-27	121.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
DTH2_k127_6511138_24	714943.Mucpa_2551	1.872e-06	49.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6511138_5	929556.Solca_3521	1.964e-195	621.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
DTH2_k127_6511138_2	929556.Solca_3842	1.597e-243	794.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
DTH2_k127_6511138_19	153721.MYP_1664	6.112e-39	149.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
DTH2_k127_6511138_7	760192.Halhy_4030	5.669e-123	416.0	COG1729@1|root,COG4783@1|root,COG1729@2|Bacteria,COG4783@2|Bacteria,4PKMW@976|Bacteroidetes,1J0XE@117747|Sphingobacteriia	976|Bacteroidetes	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
DTH2_k127_6511138_14	929562.Emtol_0647	1.563e-83	283.0	COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,47KW5@768503|Cytophagia	976|Bacteroidetes	S	PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
DTH2_k127_6520628_2	946077.W5A_06446	3.616e-104	351.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1I95J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6520628_3	946077.W5A_06441	7.397e-104	341.0	COG1136@1|root,COG1136@2|Bacteria,4PP61@976|Bacteroidetes,1IKFG@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_6520628_1	946077.W5A_06436	2.279e-113	378.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1HXJE@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_6520628_0	946077.W5A_06431	9.442e-129	422.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1I6UH@117743|Flavobacteriia	976|Bacteroidetes	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH2_k127_6520628_4	1168034.FH5T_17095	2.701e-12	67.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,2FSCB@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
DTH2_k127_6527144_4	1121957.ATVL01000011_gene3946	2.814e-111	366.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KDQ@768503|Cytophagia	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH2_k127_6527144_8	755732.Fluta_4050	1.532e-63	233.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_6527144_6	468059.AUHA01000004_gene2275	1.594e-81	277.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DTH2_k127_6527144_2	1408473.JHXO01000011_gene3152	4.408e-179	600.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
DTH2_k127_6527144_7	755732.Fluta_1586	1.867e-64	243.0	COG4773@1|root,COG4773@2|Bacteria,4PKTX@976|Bacteroidetes,1HXIR@117743|Flavobacteriia,2PB19@246874|Cryomorphaceae	976|Bacteroidetes	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
DTH2_k127_6527144_9	643867.Ftrac_2948	4.178e-41	153.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
DTH2_k127_6527144_3	655815.ZPR_0495	1.503e-118	389.0	COG1541@1|root,COG1541@2|Bacteria,4PKAN@976|Bacteroidetes,1HX4F@117743|Flavobacteriia	976|Bacteroidetes	H	PFAM Acyl-protein synthetase, LuxE	luxE	-	-	-	-	-	-	-	-	-	-	-	LuxE
DTH2_k127_6527144_11	1313301.AUGC01000017_gene818	6.82e-05	52.0	2E691@1|root,330X3@2|Bacteria,4NVM3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6527144_10	269798.CHU_0076	5.61e-39	165.0	COG1807@1|root,COG1807@2|Bacteria,4NP7Y@976|Bacteroidetes,47UYH@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6527144_5	1042376.AFPK01000042_gene1708	2.543e-105	350.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,405VQ@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH2_k127_6527144_0	1122621.ATZA01000032_gene3050	1.539e-185	594.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DTH2_k127_6527144_1	869213.JCM21142_93814	5.83e-185	583.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_6529653_18	1392490.JHZX01000001_gene420	1.409e-11	64.0	2EG2R@1|root,339UQ@2|Bacteria,4NYD4@976|Bacteroidetes,1IA1Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_24	886379.AEWI01000053_gene2706	2.326e-06	51.0	2B2PH@1|root,31V97@2|Bacteria,4P7QK@976|Bacteroidetes,2FZV0@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_16	886379.AEWI01000053_gene2706	6.789e-18	87.0	2B2PH@1|root,31V97@2|Bacteria,4P7QK@976|Bacteroidetes,2FZV0@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_13	1120966.AUBU01000030_gene2984	2.038e-42	157.0	29YB4@1|root,30K5C@2|Bacteria,4PB90@976|Bacteroidetes,47VG6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_27	1121931.AUHG01000006_gene929	0.000158	45.0	2DN6A@1|root,32VST@2|Bacteria,4NUDU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_10	411477.PARMER_01066	2.107e-61	212.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,2FPSJ@200643|Bacteroidia,2308M@171551|Porphyromonadaceae	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_21	411467.BACCAP_04464	1.964e-09	59.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_17	1313421.JHBV01000022_gene4751	1.281e-14	86.0	COG2353@1|root,COG3291@1|root,COG2353@2|Bacteria,COG3291@2|Bacteria,4PPW3@976|Bacteroidetes	2|Bacteria	S	Pkd domain containing protein	wcoB	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix,CHU_C,PKD,SprB
DTH2_k127_6529653_15	391598.FBBAL38_10944	1.735e-19	102.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,Cleaved_Adhesin,DUF1080
DTH2_k127_6529653_4	877418.ATWV01000002_gene978	5.107e-118	389.0	COG2502@1|root,COG2502@2|Bacteria,2J5NE@203691|Spirochaetes	203691|Spirochaetes	F	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
DTH2_k127_6529653_9	762903.Pedsa_0651	4.167e-63	227.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1IQJU@117747|Sphingobacteriia	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
DTH2_k127_6529653_1	1227739.Hsw_4153	6.171e-135	438.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	aroF	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
DTH2_k127_6529653_6	1124780.ANNU01000042_gene610	4.533e-100	335.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,47MW1@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH2_k127_6529653_8	1123248.KB893320_gene3893	1.651e-72	253.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IXCE@117747|Sphingobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
DTH2_k127_6529653_5	1048983.EL17_01805	5.661e-105	357.0	COG3011@1|root,COG3011@2|Bacteria,4NIS5@976|Bacteroidetes,47JWB@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_0	1121104.AQXH01000003_gene424	1.524e-151	488.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes	976|Bacteroidetes	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DTH2_k127_6529653_12	1122176.KB903535_gene1970	1.819e-50	197.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
DTH2_k127_6529653_7	1313421.JHBV01000007_gene4280	7.403e-98	342.0	COG0729@1|root,COG0729@2|Bacteria,4PKYQ@976|Bacteroidetes,1IS7K@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
DTH2_k127_6529653_14	1408433.JHXV01000001_gene833	2.351e-25	118.0	2A92F@1|root,30Y6G@2|Bacteria,4PBXE@976|Bacteroidetes,1IMRH@117743|Flavobacteriia,2PBQ0@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_11	1121129.KB903360_gene3659	5.638e-58	205.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,2FSJX@200643|Bacteroidia,2304P@171551|Porphyromonadaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
DTH2_k127_6529653_3	929556.Solca_0932	6.792e-126	415.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH2_k127_6529653_2	929556.Solca_0931	5.797e-132	445.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
DTH2_k127_6529653_23	1406840.Q763_03735	3.922e-08	61.0	2A25C@1|root,30QFR@2|Bacteria,4PCPZ@976|Bacteroidetes,1ID8R@117743|Flavobacteriia,2NXQY@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6529653_26	391598.FBBAL38_00485	4.389e-05	46.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
DTH2_k127_6529653_20	1123508.JH636439_gene1132	1.352e-09	61.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
DTH2_k127_6542535_13	1408433.JHXV01000030_gene1398	7.165e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes,1ICNQ@117743|Flavobacteriia,2PBCJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6542535_2	762903.Pedsa_3566	1.98e-82	278.0	COG3132@1|root,COG3132@2|Bacteria,4NG7X@976|Bacteroidetes,1IRRC@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
DTH2_k127_6542535_4	1123234.AUKI01000002_gene1797	4.327e-81	278.0	COG1073@1|root,COG1073@2|Bacteria,4NH47@976|Bacteroidetes,1HYN1@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,DLH,Hydrolase_4,Peptidase_S9
DTH2_k127_6542535_6	700598.Niako_4028	3.771e-61	217.0	COG0778@1|root,COG0778@2|Bacteria,4NPZV@976|Bacteroidetes	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DTH2_k127_6542535_9	509635.N824_17590	3.396e-36	142.0	COG0791@1|root,COG0791@2|Bacteria,4NUNS@976|Bacteroidetes,1ITXU@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG0791 Cell wall-associated hydrolase (invasion-associated protein)	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
DTH2_k127_6542535_0	929562.Emtol_2583	5.984e-185	586.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_6542535_12	1121897.AUGO01000008_gene2545	1.667e-05	57.0	COG4886@1|root,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia,2NT0J@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_6542535_10	926566.Terro_2525	1.522e-27	128.0	COG2133@1|root,COG2373@1|root,COG3391@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria,COG3391@2|Bacteria,3Y49I@57723|Acidobacteria,2JI4I@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,VCBS
DTH2_k127_6542535_1	1267211.KI669560_gene2209	8.684e-175	555.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
DTH2_k127_6542535_7	485918.Cpin_0942	2.503e-45	167.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1IT12@117747|Sphingobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_6542535_5	1408422.JHYF01000013_gene484	1.621e-77	265.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,36EC2@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_6542535_8	313606.M23134_04812	2.633e-38	156.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
DTH2_k127_6542535_11	1349822.NSB1T_11350	1.448e-05	56.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_6542535_3	371731.Rsw2DRAFT_3097	1.284e-81	282.0	COG4782@1|root,COG4782@2|Bacteria,1R573@1224|Proteobacteria,2U4A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
DTH2_k127_6554317_0	1453500.AT05_01505	1.711e-121	400.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH2_k127_6554317_1	411154.GFO_3114	2.317e-06	55.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1I2T2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
DTH2_k127_6558673_19	926562.Oweho_0880	3.676e-07	63.0	COG1361@1|root,COG3291@1|root,COG4935@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NGW4@976|Bacteroidetes,1IK8B@117743|Flavobacteriia	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
DTH2_k127_6558673_18	313606.M23134_00106	7.322e-09	68.0	COG1649@1|root,COG3291@1|root,COG4733@1|root,COG1649@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NJK3@976|Bacteroidetes,47TYM@768503|Cytophagia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43
DTH2_k127_6558673_16	714943.Mucpa_3747	8.376e-18	97.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,1IZ2D@117747|Sphingobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
DTH2_k127_6558673_6	762903.Pedsa_2229	1.048e-108	357.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_6558673_5	1408433.JHXV01000015_gene1787	1.042e-113	375.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia,2PA79@246874|Cryomorphaceae	976|Bacteroidetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DTH2_k127_6558673_12	755732.Fluta_0165	7.235e-34	134.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
DTH2_k127_6558673_4	1202532.FF52_13161	6.56e-130	422.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1HWMJ@117743|Flavobacteriia,2NTWP@237|Flavobacterium	976|Bacteroidetes	EJ	1-alkyl-2-acetylglycerophosphocholine esterase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DTH2_k127_6558673_21	1122176.KB903554_gene3803	6.51e-07	59.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	LysM,TPR_16,TPR_6,YfiO
DTH2_k127_6558673_7	1121007.AUML01000003_gene2535	2.016e-77	263.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia,2YI67@290174|Aquimarina	976|Bacteroidetes	J	Polypeptide deformylase	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DTH2_k127_6558673_1	1235813.JCM10003_2390	3.14e-212	669.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,4AMQC@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DTH2_k127_6558673_14	1454007.JAUG01000027_gene2771	2.803e-30	126.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1ITIS@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_6558673_15	1121129.KB903367_gene2743	5.109e-26	110.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,2FTXK@200643|Bacteroidia,22YDB@171551|Porphyromonadaceae	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
DTH2_k127_6558673_13	714943.Mucpa_4945	4.559e-32	137.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1IP6W@117747|Sphingobacteriia	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
DTH2_k127_6558673_9	762903.Pedsa_2080	3.016e-51	187.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS97@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
DTH2_k127_6558673_20	646529.Desaci_2609	5.113e-07	57.0	2CKD9@1|root,333BQ@2|Bacteria,1VIGZ@1239|Firmicutes,249NF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6558673_10	1121904.ARBP01000018_gene2602	2.931e-46	177.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
DTH2_k127_6558673_11	1168289.AJKI01000011_gene614	3.761e-38	150.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,2FSG4@200643|Bacteroidia,3XK7H@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal silencing factor during starvation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
DTH2_k127_6558673_0	926562.Oweho_1567	1.422e-266	838.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia,2PA4Q@246874|Cryomorphaceae	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
DTH2_k127_6558673_2	1122621.ATZA01000056_gene4085	2.942e-169	538.0	COG4260@1|root,COG4260@2|Bacteria,4NHXG@976|Bacteroidetes,1IQIC@117747|Sphingobacteriia	976|Bacteroidetes	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339
DTH2_k127_6558673_3	643867.Ftrac_1079	1.483e-133	437.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,47JD1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM flavoprotein, HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH2_k127_6558673_17	1137281.D778_00521	1.409e-09	69.0	2EJF4@1|root,33D63@2|Bacteria,4NYN0@976|Bacteroidetes,1IJIP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6558673_8	869213.JCM21142_517	9.989e-74	254.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_6571792_5	755732.Fluta_1225	6.145e-77	270.0	COG3023@1|root,COG3023@2|Bacteria,4NN1U@976|Bacteroidetes	976|Bacteroidetes	V	COGs COG3023 Negative regulator of beta-lactamase expression	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CUB
DTH2_k127_6571792_2	1237149.C900_03832	2.766e-117	382.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH2_k127_6571792_3	700598.Niako_1886	8.332e-108	354.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1IQ62@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH2_k127_6571792_4	1237149.C900_03830	5.782e-89	304.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47T9B@768503|Cytophagia	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_6571792_0	153721.MYP_4507	0.0	1338.0	COG2373@1|root,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,47K94@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_comp,A2M_recep,CarbopepD_reg_2,Plug,Thiol-ester_cl
DTH2_k127_6571792_7	929703.KE386491_gene4202	1.118e-31	133.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47K73@768503|Cytophagia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
DTH2_k127_6571792_1	1267211.KI669560_gene1020	5.773e-308	973.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IWT6@117747|Sphingobacteriia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_6571792_6	1121887.AUDK01000008_gene1203	1.542e-42	177.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1ICYX@117743|Flavobacteriia,2NW87@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_6572728_1	1313421.JHBV01000019_gene5384	6.098e-10	69.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_6572728_0	1408433.JHXV01000005_gene2257	3.829e-181	586.0	COG2931@1|root,COG2931@2|Bacteria,4P2B3@976|Bacteroidetes,1I8WB@117743|Flavobacteriia,2PBTD@246874|Cryomorphaceae	976|Bacteroidetes	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6572728_2	760192.Halhy_0819	2.535e-09	59.0	2EDUU@1|root,337PY@2|Bacteria,4NV32@976|Bacteroidetes,1IZUE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6593934_16	867900.Celly_1422	3.944e-17	81.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia,1F862@104264|Cellulophaga	976|Bacteroidetes	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DTH2_k127_6593934_12	313606.M23134_05531	3.848e-44	170.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47JI7@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH2_k127_6593934_14	926562.Oweho_2182	4.841e-29	118.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1IBR4@117743|Flavobacteriia,2PB5V@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
DTH2_k127_6593934_11	1313421.JHBV01000138_gene1228	4.94e-45	166.0	COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,1ITSJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_6593934_8	926562.Oweho_2361	4.251e-67	241.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia,2PBQF@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_6593934_9	714943.Mucpa_5350	3.111e-57	205.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH2_k127_6593934_2	509635.N824_13290	7.244e-104	353.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_6593934_10	1121373.KB903628_gene1451	1.249e-52	199.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,47MHD@768503|Cytophagia	976|Bacteroidetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
DTH2_k127_6593934_4	1185876.BN8_01503	1.481e-93	321.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_6593934_6	755732.Fluta_3696	5.579e-89	298.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1HWJY@117743|Flavobacteriia,2PA64@246874|Cryomorphaceae	976|Bacteroidetes	P	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH2_k127_6593934_5	1150600.ADIARSV_1895	1.32e-92	317.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH2_k127_6593934_0	929556.Solca_1727	0.0	1285.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH2_k127_6593934_7	485918.Cpin_6595	1.173e-76	278.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1IVIF@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
DTH2_k127_6593934_15	1313421.JHBV01000042_gene3261	8.812e-21	105.0	COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes	976|Bacteroidetes	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH2_k127_6593934_3	1123277.KB893173_gene1513	8.556e-94	319.0	COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,47PNV@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
DTH2_k127_6593934_1	1279009.ADICEAN_00490	3.566e-215	674.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DTH2_k127_6593934_13	1408433.JHXV01000029_gene3101	2.955e-32	132.0	COG4083@1|root,COG4083@2|Bacteria,4P9XV@976|Bacteroidetes,1IM56@117743|Flavobacteriia,2PC15@246874|Cryomorphaceae	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
DTH2_k127_6593934_18	1408433.JHXV01000029_gene3104	0.0003683	45.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
DTH2_k127_6607461_7	1227739.Hsw_1619	1.618e-10	75.0	COG2911@1|root,COG3291@1|root,COG3386@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
DTH2_k127_6607461_8	1356852.N008_09835	9.932e-06	59.0	COG2374@1|root,COG4447@1|root,COG2374@2|Bacteria,COG4447@2|Bacteria,4PPNQ@976|Bacteroidetes,47YQD@768503|Cytophagia	976|Bacteroidetes	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6607461_0	926562.Oweho_1295	1.166e-198	645.0	COG1629@1|root,COG4771@2|Bacteria,4PPAD@976|Bacteroidetes	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_6607461_4	1416760.AYMS01000012_gene963	1.712e-72	248.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1HX1J@117743|Flavobacteriia,47HUN@76831|Myroides	976|Bacteroidetes	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
DTH2_k127_6607461_6	926562.Oweho_2251	1.388e-42	159.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1I2P9@117743|Flavobacteriia,2PB1D@246874|Cryomorphaceae	976|Bacteroidetes	Q	Thioesterase superfamily	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
DTH2_k127_6607461_9	1121896.JMLU01000004_gene2644	0.0002093	49.0	2AIZR@1|root,319HS@2|Bacteria,4P8CX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6607461_1	421072.IO89_05265	1.008e-181	576.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWZU@117743|Flavobacteriia,3HGTQ@358033|Chryseobacterium	976|Bacteroidetes	I	Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA	pcaF	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_6607461_2	485918.Cpin_1071	6.58e-131	427.0	COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,1IPD6@117747|Sphingobacteriia	976|Bacteroidetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH2_k127_6607461_3	929556.Solca_3861	3.766e-78	273.0	28IZ7@1|root,2Z8WQ@2|Bacteria,4NIAK@976|Bacteroidetes,1IVBS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6607461_5	755732.Fluta_2316	1.405e-60	212.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia,2PAV8@246874|Cryomorphaceae	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
DTH2_k127_6608157_10	1313421.JHBV01000138_gene1210	2.413e-54	211.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NH2P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6608157_9	1453500.AT05_00070	3.129e-55	199.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia	976|Bacteroidetes	I	Isopentenyl-diphosphate delta-isomerase	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
DTH2_k127_6608157_5	755732.Fluta_0935	6.903e-110	362.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,1HXBH@117743|Flavobacteriia,2PAPZ@246874|Cryomorphaceae	976|Bacteroidetes	I	Squalene/phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
DTH2_k127_6608157_1	1237149.C900_03621	3.376e-194	616.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_6608157_3	938709.AUSH02000045_gene479	9.508e-174	558.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes	976|Bacteroidetes	Q	Phytoene dehydrogenase and related	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_6608157_12	468059.AUHA01000002_gene184	1.12e-33	137.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,1IT8X@117747|Sphingobacteriia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
DTH2_k127_6608157_6	468059.AUHA01000002_gene1268	1.339e-63	225.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,1IRYT@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM lycopene cyclase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6608157_4	761193.Runsl_4024	8.625e-158	503.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,47NZ3@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_6608157_14	869213.JCM21142_3966	4.375e-24	112.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6608157_8	927658.AJUM01000040_gene908	5.683e-63	218.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,2FSMJ@200643|Bacteroidia,3XK0R@558415|Marinilabiliaceae	976|Bacteroidetes	FJ	MafB19-like deaminase	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
DTH2_k127_6608157_13	1453500.AT05_10790	3.697e-29	120.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
DTH2_k127_6608157_11	1276756.AUEX01000044_gene2617	5.688e-47	183.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VM1W@28216|Betaproteobacteria,4AG0V@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
DTH2_k127_6608157_7	1267211.KI669560_gene2791	4.547e-63	226.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1IS3D@117747|Sphingobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
DTH2_k127_6608157_0	1168034.FH5T_20930	1.126e-271	850.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH2_k127_6608157_15	762903.Pedsa_1597	1.686e-19	93.0	COG0845@1|root,COG2608@1|root,COG0845@2|Bacteria,COG2608@2|Bacteria,4PHXN@976|Bacteroidetes,1IP2I@117747|Sphingobacteriia	976|Bacteroidetes	MP	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
DTH2_k127_6608157_2	1267211.KI669560_gene90	1.001e-186	608.0	COG1629@1|root,COG2608@1|root,COG2608@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IP85@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
DTH2_k127_6608157_19	1392490.JHZX01000001_gene559	0.0003859	52.0	COG3210@1|root,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6608157_17	761193.Runsl_0605	6.296e-08	64.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,47UBG@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_6836716_9	1121285.AUFK01000011_gene499	7.12e-13	81.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,3ZSPI@59732|Chryseobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
DTH2_k127_6836716_4	755732.Fluta_0748	5.445e-38	158.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_6836716_8	1120965.AUBV01000004_gene677	2.984e-20	92.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,47S1U@768503|Cytophagia	976|Bacteroidetes	C	PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
DTH2_k127_6836716_0	1453500.AT05_07745	8.277e-266	825.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1HWM2@117743|Flavobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH2_k127_6836716_2	929556.Solca_2956	3.122e-83	287.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1IQGU@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
DTH2_k127_6836716_7	313606.M23134_01092	7.931e-21	100.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Flg_new,LRR_4,LRR_6,LRR_8,VPEP
DTH2_k127_6836716_3	1408433.JHXV01000021_gene1671	7.568e-78	288.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4PPWM@976|Bacteroidetes	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	3.1.3.3	ko:K02660,ko:K07315,ko:K17763,ko:K20971,ko:K21009	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022,ko02035,ko02044,ko03021	-	-	-	CBS,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD_5,HisKA,PAS,PAS_3,PAS_4,PAS_9,STAS,SpoIIE,dCache_1
DTH2_k127_6836716_1	153721.MYP_2914	7.159e-88	316.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_6836716_5	869213.JCM21142_41705	1.876e-34	134.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
DTH2_k127_6836716_6	1453500.AT05_04470	2.008e-29	136.0	2EW37@1|root,33PGF@2|Bacteria,4P22D@976|Bacteroidetes,1I7PK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6848853_0	1492737.FEM08_15370	2.339e-280	867.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia,2NV5A@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_6848853_2	1341155.FSS13T_09470	1.281e-259	806.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia,2NT1X@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_6848853_21	929556.Solca_0475	1.106e-27	121.0	2E0EN@1|root,32W13@2|Bacteria,4NTH2@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6848853_10	153721.MYP_742	3.872e-125	413.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,47MW2@768503|Cytophagia	976|Bacteroidetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DTH2_k127_6848853_17	1107311.Q767_13880	8.409e-75	256.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,1I1JP@117743|Flavobacteriia,2NVYB@237|Flavobacterium	976|Bacteroidetes	Q	Thiopurine S-methyltransferase (TPMT)	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
DTH2_k127_6848853_6	714943.Mucpa_4381	3.735e-148	478.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_6848853_28	1189612.A33Q_0084	6.102e-09	62.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,47KKB@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH2_k127_6848853_18	1094466.KQS_07115	1.05e-69	238.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2NWCA@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DTH2_k127_6848853_8	926549.KI421517_gene2558	4.596e-129	424.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH2_k127_6848853_23	1517682.HW49_05310	5.7e-27	123.0	2D45Q@1|root,32TGB@2|Bacteria,4NTFZ@976|Bacteroidetes,2FU27@200643|Bacteroidia,230P4@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6848853_16	1189619.pgond44_04780	7.027e-78	266.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia,4C34Y@83612|Psychroflexus	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DTH2_k127_6848853_14	991.IW20_08775	4.593e-88	301.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,2NTTH@237|Flavobacterium	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH2_k127_6848853_24	760192.Halhy_1315	4.96e-24	112.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6848853_7	760192.Halhy_1314	1.33e-139	458.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1IS31@117747|Sphingobacteriia	976|Bacteroidetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
DTH2_k127_6848853_4	880070.Cycma_1865	1.083e-228	716.0	COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,47JRY@768503|Cytophagia	976|Bacteroidetes	E	PFAM Serine dehydratase alpha chain	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
DTH2_k127_6848853_9	880071.Fleli_2454	1.218e-128	422.0	COG1996@1|root,COG1996@2|Bacteria,4NFZ3@976|Bacteroidetes	976|Bacteroidetes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6848853_19	755732.Fluta_3294	7.824e-43	168.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
DTH2_k127_6848853_1	700598.Niako_2188	3.149e-268	848.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_6848853_13	1403819.BATR01000096_gene3091	2.05e-98	338.0	COG1680@1|root,COG1680@2|Bacteria,46VJ9@74201|Verrucomicrobia,2IUVM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3887
DTH2_k127_6848853_12	1121896.JMLU01000004_gene2710	6.36e-120	389.0	COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1HXVW@117743|Flavobacteriia,2NTAA@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
DTH2_k127_6848853_3	755732.Fluta_0865	7.576e-243	771.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,1I0V4@117743|Flavobacteriia	976|Bacteroidetes	P	Transporter	nhaS3	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DTH2_k127_6848853_27	485918.Cpin_3718	7.45e-14	76.0	COG0011@1|root,COG0011@2|Bacteria,4NVNG@976|Bacteroidetes	976|Bacteroidetes	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
DTH2_k127_6848853_26	1250005.PHEL85_1229	3.429e-14	78.0	COG3427@1|root,COG3427@2|Bacteria,4NQ8H@976|Bacteroidetes,1I307@117743|Flavobacteriia,3VWH8@52959|Polaribacter	976|Bacteroidetes	S	Orotate phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6848853_15	755732.Fluta_2667	9.963e-88	294.0	COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,1HXXU@117743|Flavobacteriia,2PANI@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10,4.1.1.23	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
DTH2_k127_6848853_20	714943.Mucpa_6280	5.928e-39	153.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1IT0F@117747|Sphingobacteriia	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_6848853_22	509635.N824_12600	5.653e-27	121.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1ISXT@117747|Sphingobacteriia	976|Bacteroidetes	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_6848853_5	1124780.ANNU01000003_gene1409	3.142e-163	540.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH2_k127_6848853_25	1317122.ATO12_22905	1.545e-20	104.0	COG3307@1|root,COG3307@2|Bacteria,4NUP9@976|Bacteroidetes,1I5N6@117743|Flavobacteriia,2YH0B@290174|Aquimarina	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_6848853_11	1121342.AUCO01000014_gene1919	2.603e-123	407.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,24BT3@186801|Clostridia,36F7W@31979|Clostridiaceae	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_6848853_29	936375.HMPREF1152_1727	1.884e-05	48.0	COG0726@1|root,COG0726@2|Bacteria,1VI89@1239|Firmicutes,24F3G@186801|Clostridia	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6854132_29	869213.JCM21142_52210	4.938e-10	63.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,47KM1@768503|Cytophagia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
DTH2_k127_6854132_7	153721.MYP_2233	6.779e-145	464.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,47KQ7@768503|Cytophagia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
DTH2_k127_6854132_27	1121373.KB903632_gene526	2.885e-24	103.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,47RA0@768503|Cytophagia	976|Bacteroidetes	O	NifU domain protein	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
DTH2_k127_6854132_9	714943.Mucpa_3163	2.98e-135	439.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DTH2_k127_6854132_19	1089547.KB913013_gene2740	2.297e-52	192.0	COG1595@1|root,COG1595@2|Bacteria,4NM40@976|Bacteroidetes,47PTU@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH2_k127_6854132_14	926549.KI421517_gene1374	1.516e-73	260.0	COG0265@1|root,COG0265@2|Bacteria,4NGA4@976|Bacteroidetes,47P0I@768503|Cytophagia	976|Bacteroidetes	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
DTH2_k127_6854132_30	1203611.KB894547_gene2676	1.909e-09	68.0	2EHJH@1|root,33BBD@2|Bacteria,4PMZ1@976|Bacteroidetes,2G0M1@200643|Bacteroidia,22VM1@171550|Rikenellaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6854132_13	388413.ALPR1_20958	1.061e-75	265.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
DTH2_k127_6854132_5	196490.AUEZ01000022_gene912	2.158e-177	565.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,3JSXW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_6854132_4	762903.Pedsa_1866	7.187e-181	574.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DTH2_k127_6854132_3	1121373.KB903626_gene3252	2.82e-238	743.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47K0E@768503|Cytophagia	976|Bacteroidetes	C	Dihydrolipoyl dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
DTH2_k127_6854132_10	1123234.AUKI01000005_gene132	2.877e-112	381.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1HY5K@117743|Flavobacteriia	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH2_k127_6854132_0	1270196.JCKI01000007_gene2390	0.0	1435.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
DTH2_k127_6854132_8	1121373.KB903625_gene3160	8.171e-142	487.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_6854132_16	1296416.JACB01000032_gene2291	1.425e-65	233.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1I0QN@117743|Flavobacteriia,2YJJY@290174|Aquimarina	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_6854132_22	1121373.KB903626_gene3331	9.838e-46	171.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DTH2_k127_6854132_1	1086011.HJ01_00760	2.539e-260	809.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia,2NUBG@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH2_k127_6854132_15	398720.MED217_01120	2.11e-72	256.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1HXSS@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
DTH2_k127_6854132_21	1406840.Q763_16875	1.125e-48	177.0	COG2350@1|root,COG2350@2|Bacteria,4NRC1@976|Bacteroidetes,1I447@117743|Flavobacteriia,2P0AS@237|Flavobacterium	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
DTH2_k127_6854132_17	509635.N824_21770	4.424e-64	223.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,1IRVT@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DTH2_k127_6854132_2	743722.Sph21_1238	7.708e-246	763.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1IQTE@117747|Sphingobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH2_k127_6854132_26	926549.KI421517_gene2146	1.864e-25	113.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,47RPQ@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
DTH2_k127_6854132_18	929703.KE386491_gene2765	2.35e-54	198.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
DTH2_k127_6854132_25	620914.JH621248_gene3209	9.369e-29	123.0	COG0352@1|root,COG0352@2|Bacteria,4NRDR@976|Bacteroidetes,1I374@117743|Flavobacteriia,2YHJN@290174|Aquimarina	976|Bacteroidetes	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
DTH2_k127_6854132_28	1121931.AUHG01000019_gene3038	1.597e-15	88.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
DTH2_k127_6854132_24	1380384.JADN01000004_gene1752	5.797e-32	138.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia	976|Bacteroidetes	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
DTH2_k127_6854132_23	1454007.JAUG01000139_gene4166	6.627e-43	169.0	COG2374@1|root,COG2911@1|root,COG3210@1|root,COG4733@1|root,COG5492@1|root,COG2374@2|Bacteria,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	LTD
DTH2_k127_6854132_11	1121904.ARBP01000033_gene3216	5.486e-91	318.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_6854132_12	1408473.JHXO01000001_gene2425	4.863e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulatory protein	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_6854132_20	925409.KI911562_gene2443	7.846e-51	183.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
DTH2_k127_6854132_6	655815.ZPR_0090	1.87e-146	475.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
DTH2_k127_6890030_0	643867.Ftrac_1237	4.22e-32	141.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_6902276_10	1336803.PHEL49_0218	2.894e-111	364.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1HXGE@117743|Flavobacteriia,3VVSE@52959|Polaribacter	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DTH2_k127_6902276_17	1124780.ANNU01000050_gene2107	2.059e-86	297.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
DTH2_k127_6902276_13	929713.NIASO_04435	1.225e-101	341.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,1INUS@117747|Sphingobacteriia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
DTH2_k127_6902276_7	926562.Oweho_2456	7.774e-129	427.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2PACQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
DTH2_k127_6902276_30	1121904.ARBP01000002_gene7285	7.636e-33	130.0	COG1393@1|root,COG1393@2|Bacteria,4NSA6@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
DTH2_k127_6902276_29	926562.Oweho_2363	1.588e-37	149.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia,2PB38@246874|Cryomorphaceae	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
DTH2_k127_6902276_4	867902.Ornrh_0829	5.697e-147	472.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1HXZY@117743|Flavobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_6902276_36	1408433.JHXV01000009_gene1339	1.177e-17	93.0	COG3011@1|root,COG3011@2|Bacteria,4NQY0@976|Bacteroidetes,1IIAF@117743|Flavobacteriia	976|Bacteroidetes	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
DTH2_k127_6902276_0	509635.N824_05040	8.661e-230	731.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1IRKI@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DTH2_k127_6902276_37	5476.C4YI18	2.05e-10	67.0	2B11K@1|root,2S09A@2759|Eukaryota,3A2XC@33154|Opisthokonta,3P3PA@4751|Fungi,3QVED@4890|Ascomycota,3RUMJ@4891|Saccharomycetes,47AMB@766764|Debaryomycetaceae	4751|Fungi	-	-	-	-	-	ko:K05747,ko:K20521	ko04062,ko04144,ko04520,ko04530,ko04666,ko04810,ko05100,ko05130,ko05131,ko05132,ko05231,map04062,map04144,map04520,map04530,map04666,map04810,map05100,map05130,map05131,map05132,map05231	-	-	-	ko00000,ko00001,ko04131,ko04812	-	-	-	-
DTH2_k127_6902276_2	485917.Phep_4190	3.792e-184	587.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
DTH2_k127_6902276_19	755732.Fluta_2303	2.288e-73	253.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1HXZG@117743|Flavobacteriia,2PAW3@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
DTH2_k127_6902276_32	269798.CHU_2230	3.724e-26	111.0	2E3V1@1|root,32YSA@2|Bacteria,4NV88@976|Bacteroidetes,47S3J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6902276_1	1191523.MROS_0698	2.721e-194	616.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_6902276_11	984262.SGRA_1047	2.107e-105	353.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH2_k127_6902276_34	313606.M23134_08246	5.639e-22	98.0	2CUMY@1|root,32SVM@2|Bacteria,4NTF0@976|Bacteroidetes,47RDV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DTH2_k127_6902276_8	926562.Oweho_2435	6.66e-122	400.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia,2PAY6@246874|Cryomorphaceae	976|Bacteroidetes	E	Arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_6902276_20	929703.KE386491_gene437	9.35e-68	236.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,47P7A@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
DTH2_k127_6902276_25	742817.HMPREF9449_00873	2.006e-45	170.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,2FM82@200643|Bacteroidia,22YAY@171551|Porphyromonadaceae	976|Bacteroidetes	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
DTH2_k127_6902276_22	1150600.ADIARSV_1583	4.163e-56	207.0	COG1864@1|root,COG1864@2|Bacteria,4NFYJ@976|Bacteroidetes,1IY0Z@117747|Sphingobacteriia	976|Bacteroidetes	F	DNA/RNA non-specific endonuclease	nucA_1	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
DTH2_k127_6902276_38	391596.PBAL39_22140	2.436e-09	59.0	2ADY7@1|root,313QE@2|Bacteria,4NXQ1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6902276_41	1121895.Q765_18450	1.527e-06	61.0	COG2911@1|root,COG4886@1|root,COG4935@1|root,COG2911@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia,2NUTP@237|Flavobacterium	976|Bacteroidetes	O	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_6902276_33	1317122.ATO12_01935	5.863e-26	112.0	COG0662@1|root,COG0662@2|Bacteria,4NVCS@976|Bacteroidetes,1IHUF@117743|Flavobacteriia,2YJQ6@290174|Aquimarina	976|Bacteroidetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MannoseP_isomer
DTH2_k127_6902276_27	760192.Halhy_3096	4.968e-43	181.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_6902276_28	1313421.JHBV01000016_gene5582	3.129e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,4NT79@976|Bacteroidetes,1IZNZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_6902276_6	1168034.FH5T_04685	3.263e-137	479.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia	976|Bacteroidetes	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_6902276_14	655815.ZPR_0120	4.084e-99	329.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DTH2_k127_6902276_12	746697.Aeqsu_0924	4.316e-105	353.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,1HXWZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_6902276_24	1484460.JSWG01000010_gene3208	1.684e-48	180.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1I1RZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	3-oxoacyl-(ACP) synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6902276_31	1236514.BAKL01000022_gene2137	7.462e-29	117.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,2FTE9@200643|Bacteroidia,4ARNF@815|Bacteroidaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_6902276_5	525257.HMPREF0204_10998	1.039e-139	454.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1HY14@117743|Flavobacteriia,3ZP1M@59732|Chryseobacterium	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_6902276_16	1197477.IA57_04660	9.33e-88	301.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia	976|Bacteroidetes	IQ	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
DTH2_k127_6902276_26	1123008.KB905694_gene1762	1.351e-44	171.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,2FR15@200643|Bacteroidia,22XVJ@171551|Porphyromonadaceae	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
DTH2_k127_6902276_21	153721.MYP_4268	3.014e-59	211.0	COG2834@1|root,COG2834@2|Bacteria,4NT30@976|Bacteroidetes,47RSE@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
DTH2_k127_6902276_40	1317122.ATO12_16860	1.317e-08	64.0	29ETG@1|root,301R8@2|Bacteria,4NSXB@976|Bacteroidetes,1I28V@117743|Flavobacteriia,2YGZ5@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6902276_35	1202532.FF52_12206	2.762e-18	89.0	COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,1I431@117743|Flavobacteriia,2NWCD@237|Flavobacterium	976|Bacteroidetes	I	dehydratase	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
DTH2_k127_6902276_23	714943.Mucpa_3953	1.486e-54	197.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ISQD@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
DTH2_k127_6902276_15	485918.Cpin_1896	1.425e-90	314.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
DTH2_k127_6902276_9	880070.Cycma_1374	2.113e-113	368.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,47MGG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DTH2_k127_6902276_3	1305737.JAFX01000001_gene121	1.896e-170	545.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
DTH2_k127_6902276_18	485918.Cpin_2050	7.754e-77	265.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1INRC@117747|Sphingobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
DTH2_k127_6951502_3	926549.KI421517_gene351	1.082e-42	161.0	COG0226@1|root,COG0573@1|root,COG0226@2|Bacteria,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,47KM7@768503|Cytophagia	976|Bacteroidetes	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,PBP_like_2
DTH2_k127_6951502_0	1235803.C825_01254	3.419e-116	379.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,2FMW1@200643|Bacteroidia,22X86@171551|Porphyromonadaceae	976|Bacteroidetes	P	Bacterial extracellular solute-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_6951502_2	927658.AJUM01000037_gene2071	1.106e-91	318.0	COG3746@1|root,COG3746@2|Bacteria,4NIRE@976|Bacteroidetes,2FR58@200643|Bacteroidia	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH2_k127_6951502_4	1453500.AT05_06150	3.884e-33	136.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_6951502_1	755732.Fluta_2857	4.427e-104	349.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,1HXMH@117743|Flavobacteriia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
DTH2_k127_6983558_3	984262.SGRA_2537	2.121e-133	462.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_6983558_12	1122176.KB903565_gene3420	3.102e-20	107.0	COG0726@1|root,COG3209@1|root,COG3291@1|root,COG0726@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	xlnB	GO:0005575,GO:0016020	3.2.1.156,3.2.1.8	ko:K01181,ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CHU_C,Glyco_hydro_11,PKD,Polysacc_deac_1,SprB
DTH2_k127_6983558_1	1380600.AUYN01000007_gene3238	1.867e-176	591.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
DTH2_k127_6983558_2	1408473.JHXO01000006_gene1037	2.597e-136	458.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_6983558_11	1408433.JHXV01000001_gene698	4.053e-25	110.0	COG5605@1|root,COG5605@2|Bacteria,4P9DD@976|Bacteroidetes,1IC4B@117743|Flavobacteriia,2PB81@246874|Cryomorphaceae	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
DTH2_k127_6983558_4	1121373.KB903666_gene1254	1.897e-91	306.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,47JVP@768503|Cytophagia	976|Bacteroidetes	C	cytochrome c oxidase subunit III	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_6983558_8	1380384.JADN01000004_gene2020	7.385e-46	172.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,1I1D8@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_6983558_5	1048983.EL17_04245	2.121e-77	269.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DTH2_k127_6983558_0	926562.Oweho_0868	4.708e-191	612.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia,2PAE4@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
DTH2_k127_6983558_7	1122176.KB903609_gene5155	7.189e-46	183.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,1IYSE@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_6983558_6	1408433.JHXV01000006_gene2725	7.357e-76	263.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia,2PAQC@246874|Cryomorphaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
DTH2_k127_6983558_9	688270.Celal_3799	9.308e-43	163.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia,1F92D@104264|Cellulophaga	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
DTH2_k127_6983558_10	755732.Fluta_1673	8.207e-31	139.0	COG2911@1|root,COG3266@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,4PKFD@976|Bacteroidetes,1IKC5@117743|Flavobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH2_k127_7095463_10	1034807.FBFL15_0865	8.485e-21	97.0	COG0845@1|root,COG2608@1|root,COG0845@2|Bacteria,COG2608@2|Bacteria,4NG8S@976|Bacteroidetes,1HYRA@117743|Flavobacteriia,2NUC9@237|Flavobacterium	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
DTH2_k127_7095463_6	745718.JADT01000007_gene2738	2.018e-70	244.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_7095463_4	1203611.KB894542_gene868	1.815e-83	284.0	COG0500@1|root,COG0500@2|Bacteria,4PMZA@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
DTH2_k127_7095463_0	926562.Oweho_2741	2.769e-298	949.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,1I7EU@117743|Flavobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
DTH2_k127_7095463_12	755732.Fluta_1974	4.683e-05	51.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_7095463_5	929556.Solca_1125	9.015e-83	283.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,1IPYQ@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
DTH2_k127_7095463_8	926562.Oweho_2136	1.042e-64	232.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia,2PBM7@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_7095463_3	1341155.FSS13T_26680	4.364e-85	291.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia,2NSD3@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
DTH2_k127_7095463_2	1406840.Q763_07765	4.815e-100	334.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia,2NT5Y@237|Flavobacterium	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
DTH2_k127_7095463_7	1313421.JHBV01000042_gene3343	2.617e-65	239.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_7095463_9	760192.Halhy_5070	1.874e-39	158.0	2DN4I@1|root,32VGS@2|Bacteria,4NNY4@976|Bacteroidetes,1IU3E@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
DTH2_k127_7095463_1	760192.Halhy_5071	3.097e-292	917.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IPX2@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_7332219_1	945713.IALB_0457	7.305e-120	402.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
DTH2_k127_7332219_3	761193.Runsl_3693	1.646e-57	219.0	COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,47PB5@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
DTH2_k127_7332219_0	153721.MYP_2041	2.593e-138	452.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,47KRS@768503|Cytophagia	976|Bacteroidetes	E	Alanine dehydrogenase PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_7332219_4	1408473.JHXO01000006_gene1325	1.495e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,2FYPS@200643|Bacteroidia	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DTH2_k127_7332219_2	1121100.JCM6294_2209	1.73e-99	327.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FNIS@200643|Bacteroidia,4AKNN@815|Bacteroidaceae	976|Bacteroidetes	S	ATP-binding cassette protein, ChvD family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
DTH2_k127_7481114_1	1237149.C900_04718	7.842e-14	84.0	COG2353@1|root,COG2353@2|Bacteria,4PP17@976|Bacteroidetes,47YSH@768503|Cytophagia	976|Bacteroidetes	G	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7481114_0	471854.Dfer_5793	3.683e-23	103.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_7488858_2	443143.GM18_1442	4.409e-73	251.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,43TF4@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_7488858_3	367737.Abu_0672	8.533e-73	253.0	COG0107@1|root,COG0107@2|Bacteria,1RA6Q@1224|Proteobacteria,42PND@68525|delta/epsilon subdivisions,2YT8T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Histidine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
DTH2_k127_7488858_4	760192.Halhy_3411	7.03e-52	188.0	COG0640@1|root,COG0640@2|Bacteria,4NS23@976|Bacteroidetes,1IT8B@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
DTH2_k127_7488858_5	1408473.JHXO01000005_gene1716	1.309e-29	124.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,2FU0Y@200643|Bacteroidia	976|Bacteroidetes	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
DTH2_k127_7488858_1	156889.Mmc1_2433	6.99e-97	324.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2U57D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	transport, permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
DTH2_k127_7488858_0	1202532.FF52_07794	1.686e-135	443.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1HXJV@117743|Flavobacteriia,2NT6Z@237|Flavobacterium	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	rfbB	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
DTH2_k127_7520076_6	1122225.AULQ01000006_gene1134	1.026e-47	181.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_7520076_3	755732.Fluta_2220	1.674e-70	263.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI9U@976|Bacteroidetes,1HX1I@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_7
DTH2_k127_7520076_7	1120951.AUBG01000010_gene1970	2.798e-46	175.0	COG2197@1|root,COG2197@2|Bacteria,4NN0B@976|Bacteroidetes,1I0A6@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_7520076_9	768704.Desmer_4370	1.201e-11	69.0	2AD7J@1|root,312WH@2|Bacteria,1V9CY@1239|Firmicutes,24SBJ@186801|Clostridia,265QE@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_7520076_1	927658.AJUM01000037_gene2297	1.089e-129	452.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,2G0DG@200643|Bacteroidia,3XJHT@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_7520076_2	927658.AJUM01000037_gene2298	1.842e-100	336.0	COG3291@1|root,COG3291@2|Bacteria,4NHJJ@976|Bacteroidetes,2G20Y@200643|Bacteroidia,3XJ8K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7520076_10	1120963.KB894501_gene262	5.801e-05	57.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,2Q0GU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the ompA family	yiaD	-	-	ko:K12216	-	-	-	-	ko00000,ko02044	3.A.7.9.1	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
DTH2_k127_7520076_4	927658.AJUM01000037_gene2299	2.982e-53	214.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia,3XJF6@558415|Marinilabiliaceae	976|Bacteroidetes	M	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,PKD
DTH2_k127_7520076_5	153721.MYP_1138	4.265e-51	192.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_7520076_8	1121373.KB903652_gene1471	2.204e-15	92.0	COG5184@1|root,COG5184@2|Bacteria,4PKDT@976|Bacteroidetes	976|Bacteroidetes	DZ	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_7520076_0	313606.M23134_02237	3.32e-309	1006.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_7621260_14	700598.Niako_1943	3.817e-77	268.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
DTH2_k127_7621260_4	929556.Solca_1394	1.188e-188	600.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
DTH2_k127_7621260_23	1237149.C900_03362	4.595e-29	121.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
DTH2_k127_7621260_16	1121904.ARBP01000002_gene7147	6.471e-62	221.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
DTH2_k127_7621260_3	762903.Pedsa_0375	1.303e-196	621.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1IPSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH2_k127_7621260_24	1454007.JAUG01000079_gene4539	1.302e-28	119.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,1INX3@117747|Sphingobacteriia	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH2_k127_7621260_11	929562.Emtol_2588	1.738e-137	446.0	COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,47JRK@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
DTH2_k127_7621260_0	929562.Emtol_2590	0.0	1879.0	COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran,OEP
DTH2_k127_7621260_34	1121889.AUDM01000009_gene1155	5.084e-06	54.0	2EAT9@1|root,334V5@2|Bacteria,4NUP8@976|Bacteroidetes,1IGI9@117743|Flavobacteriia,2NX2D@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7621260_10	1121373.KB903662_gene54	8.021e-145	469.0	COG2081@1|root,COG2081@2|Bacteria,4NFQ9@976|Bacteroidetes,47KHX@768503|Cytophagia	976|Bacteroidetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH2_k127_7621260_29	313603.FB2170_17341	2.025e-17	83.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia,2PHTD@252356|Maribacter	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH2_k127_7621260_15	755732.Fluta_2871	1.216e-70	244.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_7621260_32	743722.Sph21_3591	7.322e-14	73.0	COG0607@1|root,COG0607@2|Bacteria,4PGNM@976|Bacteroidetes,1ITZD@117747|Sphingobacteriia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7621260_28	755732.Fluta_2868	7.995e-25	106.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1IG8B@117743|Flavobacteriia,2PBXI@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_7621260_25	1121895.Q765_19690	9.526e-28	118.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia,2NWHP@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
DTH2_k127_7621260_19	1086011.HJ01_00039	2.633e-39	148.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia,2NX6I@237|Flavobacterium	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_7621260_33	1121012.AUKX01000013_gene2173	7.043e-08	56.0	2A7YD@1|root,30WYF@2|Bacteria,4PAAV@976|Bacteroidetes,1IFNY@117743|Flavobacteriia,23IE2@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7621260_18	468059.AUHA01000003_gene1508	3.764e-40	150.0	COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,1ITPA@117747|Sphingobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH2_k127_7621260_30	1189620.AJXL01000021_gene171	3.433e-17	86.0	COG3118@1|root,COG3118@2|Bacteria,4PCFI@976|Bacteroidetes,1ID1H@117743|Flavobacteriia,2NWVG@237|Flavobacterium	976|Bacteroidetes	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
DTH2_k127_7621260_5	865938.Weevi_0210	1.98e-185	586.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
DTH2_k127_7621260_2	1313421.JHBV01000043_gene3072	1.995e-201	632.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
DTH2_k127_7621260_6	1408433.JHXV01000011_gene2000	1.847e-184	586.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2PA4J@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
DTH2_k127_7621260_9	1197477.IA57_06300	1.493e-147	472.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1HWPD@117743|Flavobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
DTH2_k127_7621260_17	1501391.LG35_00025	1.488e-41	157.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,2FU4Q@200643|Bacteroidia,22UI1@171550|Rikenellaceae	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_7621260_36	376686.Fjoh_1582	0.0001034	49.0	2E7B2@1|root,331UG@2|Bacteria,4NUN2@976|Bacteroidetes,1I5B2@117743|Flavobacteriia,2NXGW@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7621260_20	1341155.FSS13T_07260	8.667e-35	137.0	COG0346@1|root,COG0346@2|Bacteria,4NQK6@976|Bacteroidetes,1I4MY@117743|Flavobacteriia,2NWKI@237|Flavobacterium	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
DTH2_k127_7621260_21	1131812.JQMS01000001_gene2073	2.683e-32	129.0	2AXFQ@1|root,31PF8@2|Bacteria,4NQN3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7621260_26	755732.Fluta_3198	8.71e-26	111.0	COG2259@1|root,COG2259@2|Bacteria,4NVWM@976|Bacteroidetes,1I5GY@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
DTH2_k127_7621260_31	1178825.ALIH01000006_gene1544	3.99e-15	85.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_7621260_27	755732.Fluta_3196	2.128e-25	110.0	2EDGF@1|root,337CN@2|Bacteria,4NXB6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7621260_12	153721.MYP_3607	3.254e-136	442.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
DTH2_k127_7621260_13	929562.Emtol_0376	1.388e-116	388.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DTH2_k127_7621260_8	468059.AUHA01000002_gene1060	4.671e-163	526.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
DTH2_k127_7621260_1	517418.Ctha_1714	1.9e-322	1014.0	COG0612@1|root,COG0612@2|Bacteria,1FDGF@1090|Chlorobi	1090|Chlorobi	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_7621260_7	153721.MYP_112	6.131e-172	557.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,47KSQ@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DTH2_k127_7621260_35	1227739.Hsw_0628	3.184e-05	54.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
DTH2_k127_7621260_22	247634.GPB2148_313	1.11e-30	137.0	COG1520@1|root,COG4249@1|root,COG1520@2|Bacteria,COG4249@2|Bacteria,1QSQ3@1224|Proteobacteria,1RW8C@1236|Gammaproteobacteria,1JAW1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
DTH2_k127_7630196_7	1453505.JASY01000001_gene3390	2.553e-09	64.0	COG3209@1|root,COG3209@2|Bacteria,4P674@976|Bacteroidetes,1HZZJ@117743|Flavobacteriia,2NWI4@237|Flavobacterium	976|Bacteroidetes	EM	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
DTH2_k127_7630196_0	929556.Solca_3515	6.883e-298	921.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1IR7B@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_7630196_3	945713.IALB_1637	5.957e-78	267.0	COG0605@1|root,COG0605@2|Bacteria	2|Bacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH2_k127_7630196_4	509635.N824_12955	5.738e-45	169.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1ITD7@117747|Sphingobacteriia	976|Bacteroidetes	I	Biotin lipoyl attachment domain-containing protein	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
DTH2_k127_7630196_2	755732.Fluta_1295	1.594e-87	296.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,1IMQI@117743|Flavobacteriia,2PBDZ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7630196_1	153721.MYP_1661	7.038e-119	402.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,47NYD@768503|Cytophagia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_7630196_5	181119.XP_005526438.1	5.984e-13	79.0	COG0484@1|root,KOG0712@2759|Eukaryota,38CPQ@33154|Opisthokonta,3BCGW@33208|Metazoa,3CWJE@33213|Bilateria,485P9@7711|Chordata,4910D@7742|Vertebrata,4GHF3@8782|Aves	33208|Metazoa	O	sub-family A member 2	DNAJA2	GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008047,GO:0008150,GO:0008152,GO:0008284,GO:0009987,GO:0010033,GO:0018885,GO:0030234,GO:0032781,GO:0035966,GO:0042026,GO:0042127,GO:0042221,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051082,GO:0051087,GO:0051336,GO:0051345,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071704,GO:0098772	-	ko:K09502,ko:K09503,ko:K09505	ko04141,map04141	-	-	-	ko00000,ko00001,ko03029,ko03110,ko04131	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH2_k127_7630196_6	761193.Runsl_0845	3.951e-11	64.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,47PP1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
DTH2_k127_7648392_2	525257.HMPREF0204_11308	9.82e-172	559.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,3ZRJ5@59732|Chryseobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,P_proprotein,Peptidase_M43,Reprolysin_4,Reprolysin_5
DTH2_k127_7648392_0	1168289.AJKI01000044_gene79	1.814e-317	983.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia,3XJMR@558415|Marinilabiliaceae	976|Bacteroidetes	J	Putative tRNA binding domain	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DTH2_k127_7648392_6	869213.JCM21142_93619	5.987e-33	135.0	2AFQQ@1|root,315SK@2|Bacteria,4NJD4@976|Bacteroidetes,47PFM@768503|Cytophagia	976|Bacteroidetes	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3,NUMOD4
DTH2_k127_7648392_4	1406840.Q763_04075	7.154e-103	343.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1HXC6@117743|Flavobacteriia,2NUA0@237|Flavobacterium	976|Bacteroidetes	V	Peptidase S66	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
DTH2_k127_7648392_5	313606.M23134_06222	2.36e-74	258.0	COG2267@1|root,COG2267@2|Bacteria,4NK80@976|Bacteroidetes,47NWA@768503|Cytophagia	976|Bacteroidetes	I	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH2_k127_7648392_1	1237149.C900_00016	1.211e-196	620.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
DTH2_k127_7648392_3	865937.Gilli_2438	1.86e-155	505.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia,2P6GW@244698|Gillisia	976|Bacteroidetes	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
DTH2_k127_7648392_7	997884.HMPREF1068_00534	3.971e-16	91.0	COG0406@1|root,COG2335@1|root,COG0406@2|Bacteria,COG2335@2|Bacteria,4NTT5@976|Bacteroidetes,2FQMH@200643|Bacteroidia,4AVUP@815|Bacteroidaceae	976|Bacteroidetes	GM	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_3,SusD_RagB
DTH2_k127_7648392_8	1410632.JHWW01000004_gene1583	5.485e-16	78.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,24BQ6@186801|Clostridia,27JP1@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K00786	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_7689452_6	565033.GACE_1136	8.244e-13	69.0	COG0110@1|root,arCOG01848@2157|Archaea,2Y25E@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_7689452_2	484022.Fphi_1258	7.866e-97	325.0	COG1621@1|root,COG1621@2|Bacteria,1RGK9@1224|Proteobacteria,1S0H5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7689452_3	746697.Aeqsu_2048	1.665e-72	256.0	COG3146@1|root,COG3146@2|Bacteria,4NECI@976|Bacteroidetes,1HY9G@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
DTH2_k127_7689452_1	1356852.N008_03990	3.171e-98	331.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,47JIX@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
DTH2_k127_7689452_7	1453500.AT05_04560	5.691e-08	65.0	COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD,PKD,fn3
DTH2_k127_7689452_4	1122176.KB903531_gene2762	1.305e-48	192.0	COG1572@1|root,COG4447@1|root,COG1572@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Laminin_G_3,TM_helix
DTH2_k127_7689452_0	1227739.Hsw_0809	4.443e-147	473.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47J92@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	eryC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_7689452_5	1123277.KB893211_gene4421	3.412e-15	77.0	COG1361@1|root,COG2373@1|root,COG2755@1|root,COG3291@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2755@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47K2W@768503|Cytophagia	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA
DTH2_k127_7690273_1	1267211.KI669560_gene1599	2.688e-249	778.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH2_k127_7690273_17	485918.Cpin_1422	2.991e-10	70.0	2C2QD@1|root,33JG0@2|Bacteria,4PQ05@976|Bacteroidetes,1IZHI@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7690273_3	925409.KI911562_gene190	6.972e-197	628.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH2_k127_7690273_11	266748.HY04_01000	5.094e-48	174.0	COG4319@1|root,COG4319@2|Bacteria,4NS10@976|Bacteroidetes,1II83@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
DTH2_k127_7690273_9	1107311.Q767_00240	1.189e-72	254.0	COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,1HXEP@117743|Flavobacteriia,2NSG2@237|Flavobacterium	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
DTH2_k127_7690273_6	468059.AUHA01000002_gene1394	6.434e-142	462.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_7690273_0	269798.CHU_2223	0.0	1287.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DTH2_k127_7690273_4	929562.Emtol_0674	1.186e-151	512.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_7690273_15	1300143.CCAV010000003_gene1771	5.705e-23	103.0	COG0526@1|root,COG0607@1|root,COG0526@2|Bacteria,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia,3ZTFG@59732|Chryseobacterium	976|Bacteroidetes	COP	Thioredoxin	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
DTH2_k127_7690273_12	1168289.AJKI01000007_gene113	3.257e-40	156.0	COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,2FXGQ@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
DTH2_k127_7690273_2	714943.Mucpa_3937	8.478e-200	625.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DTH2_k127_7690273_13	1121889.AUDM01000008_gene782	1.884e-30	139.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,1HZ23@117743|Flavobacteriia,2NT83@237|Flavobacterium	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
DTH2_k127_7690273_7	313606.M23134_04149	4.884e-103	345.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_7690273_5	643867.Ftrac_1237	3.414e-148	495.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_7690273_8	485918.Cpin_3624	3.228e-73	258.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1IP9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_7690273_10	504472.Slin_3586	7.614e-52	209.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Collagen_bind,DUF11,SdrD_B
DTH2_k127_7690273_14	1122176.KB903577_gene4851	1.757e-26	127.0	COG1361@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_7751835_2	1168034.FH5T_17850	1.859e-161	524.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,2G0DC@200643|Bacteroidia	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH2_k127_7751835_4	1235803.C825_03903	3.803e-112	373.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
DTH2_k127_7751835_8	153721.MYP_4106	1.256e-77	272.0	COG3391@1|root,COG3391@2|Bacteria,4NESV@976|Bacteroidetes,47MV5@768503|Cytophagia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
DTH2_k127_7751835_6	1046627.BZARG_1443	6.807e-83	286.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,4NJ39@976|Bacteroidetes,1HZRK@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
DTH2_k127_7751835_9	755732.Fluta_0016	5.813e-42	167.0	2DMBB@1|root,32GIQ@2|Bacteria,4NSXP@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4465
DTH2_k127_7751835_5	153721.MYP_4104	5.13e-95	335.0	COG4206@1|root,COG4206@2|Bacteria,4NED9@976|Bacteroidetes,47M0G@768503|Cytophagia	976|Bacteroidetes	H	TonB-dependent Receptor Plug	btuB	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
DTH2_k127_7751835_7	1120968.AUBX01000014_gene2468	1.217e-78	271.0	COG3186@1|root,COG3186@2|Bacteria,4NEX5@976|Bacteroidetes,47KWF@768503|Cytophagia	976|Bacteroidetes	E	PFAM Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
DTH2_k127_7751835_0	926549.KI421517_gene119	5.154e-313	987.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_7751835_1	1191523.MROS_1275	5.792e-283	885.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1275|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
DTH2_k127_7751835_3	755732.Fluta_1284	2.027e-128	433.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_7752359_0	1185876.BN8_00855	0.0002915	53.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,47UBG@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_7830093_15	1048983.EL17_20045	3.973e-05	59.0	2DPU6@1|root,333E2@2|Bacteria,4NW9K@976|Bacteroidetes,47RVJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7830093_6	755732.Fluta_3173	2.021e-83	317.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7830093_9	762903.Pedsa_0349	3.344e-57	211.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
DTH2_k127_7830093_12	886379.AEWI01000024_gene339	1.558e-39	149.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,2FTC9@200643|Bacteroidia,3XK94@558415|Marinilabiliaceae	976|Bacteroidetes	S	RNA polymerase Rpb6	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
DTH2_k127_7830093_3	1034807.FBFL15_1853	1.235e-138	451.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia,2NSP7@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DTH2_k127_7830093_5	869213.JCM21142_3856	1.952e-92	312.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,47N7V@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
DTH2_k127_7830093_1	929556.Solca_2898	6.652e-170	550.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1IRBF@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_7830093_2	755732.Fluta_0797	6.083e-169	542.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
DTH2_k127_7830093_16	1305737.JAFX01000001_gene1608	0.0008503	49.0	COG3637@1|root,COG3637@2|Bacteria,4NRN4@976|Bacteroidetes,47X49@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7830093_8	1121889.AUDM01000002_gene237	3.627e-68	250.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia,2NT02@237|Flavobacterium	976|Bacteroidetes	MU	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_7830093_4	926562.Oweho_2781	3.993e-128	437.0	COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia,2PBC9@246874|Cryomorphaceae	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
DTH2_k127_7830093_10	1121897.AUGO01000002_gene2130	1.577e-44	185.0	COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,1HWYH@117743|Flavobacteriia,2NSS2@237|Flavobacterium	976|Bacteroidetes	V	ABC transporter ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
DTH2_k127_7830093_7	686340.Metal_0288	8.382e-80	272.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH2_k127_7830093_13	485918.Cpin_1878	1.616e-28	122.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1ITQK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7830093_11	880070.Cycma_2333	1.189e-39	154.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,47MSF@768503|Cytophagia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
DTH2_k127_7830093_0	1122605.KB893630_gene4076	0.0	1010.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IWX4@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH2_k127_7830093_14	755732.Fluta_2885	8.155e-16	90.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_7930893_2	755732.Fluta_3106	3.031e-48	176.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_7930893_1	755732.Fluta_3107	1.818e-122	400.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	Plug,PorP_SprF,STN,TonB_dep_Rec
DTH2_k127_7930893_0	755732.Fluta_3108	5.751e-179	585.0	COG1729@1|root,COG2885@1|root,COG1729@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2PBBP@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_7977622_0	929556.Solca_2616	3.888e-314	977.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1IPB3@117747|Sphingobacteriia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
DTH2_k127_7977622_8	1121930.AQXG01000002_gene2137	3.017e-06	58.0	COG4632@1|root,COG4632@2|Bacteria,4NR1M@976|Bacteroidetes	976|Bacteroidetes	G	COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,fn3
DTH2_k127_7977622_2	926556.Echvi_1296	1.183e-192	613.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH2_k127_7977622_1	1123276.KB893249_gene448	1.115e-214	692.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_7977622_5	1237149.C900_04332	5.187e-87	304.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
DTH2_k127_7977622_6	153721.MYP_3679	6.665e-77	280.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_7977622_7	869213.JCM21142_3966	1.323e-31	136.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7977622_3	1237149.C900_00478	2.626e-141	455.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,47K90@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH2_k127_7977622_4	755732.Fluta_3918	1.211e-108	368.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1HYK9@117743|Flavobacteriia,2PBD2@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Peptidase family M1	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_8056240_39	1453500.AT05_07335	2.188e-28	115.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia	976|Bacteroidetes	I	thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH2_k127_8056240_31	313598.MED152_04235	6.587e-50	184.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia,3VVWS@52959|Polaribacter	976|Bacteroidetes	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
DTH2_k127_8056240_37	865937.Gilli_2148	2.579e-35	148.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia,2P69J@244698|Gillisia	976|Bacteroidetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_8056240_33	1237149.C900_02393	3.161e-44	172.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
DTH2_k127_8056240_36	1408473.JHXO01000006_gene1132	1.103e-37	160.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
DTH2_k127_8056240_1	385682.AFSL01000060_gene1763	5.487e-311	968.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,3XJ41@558415|Marinilabiliaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
DTH2_k127_8056240_12	714943.Mucpa_4505	2.569e-138	451.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1IR94@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_8056240_38	926562.Oweho_0083	2.165e-29	124.0	COG3117@1|root,COG3117@2|Bacteria,4P9FE@976|Bacteroidetes,1IDW5@117743|Flavobacteriia,2PB77@246874|Cryomorphaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
DTH2_k127_8056240_24	1229276.DI53_1026	2.747e-66	244.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8056240_25	1250006.JHZZ01000001_gene2068	1.2e-63	228.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia,3VVFR@52959|Polaribacter	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
DTH2_k127_8056240_47	1380600.AUYN01000006_gene320	1.34e-09	60.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8056240_14	1123277.KB893239_gene1165	4.347e-121	397.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,47M3V@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
DTH2_k127_8056240_15	1453498.LG45_09620	2.149e-112	364.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1HXG3@117743|Flavobacteriia,2NSI5@237|Flavobacterium	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	yadF	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DTH2_k127_8056240_20	945713.IALB_2759	5.891e-88	325.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,TPR_12,Y_Y_Y
DTH2_k127_8056240_22	1237149.C900_05634	1.078e-68	239.0	COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,47UM2@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_8056240_26	1380384.JADN01000003_gene759	6.578e-62	235.0	COG3858@1|root,COG3858@2|Bacteria,4NJZ6@976|Bacteroidetes,1I1G8@117743|Flavobacteriia	976|Bacteroidetes	S	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Glyco_hydro_18,Laminin_G_3
DTH2_k127_8056240_42	558152.IQ37_11520	1.249e-22	113.0	COG3023@1|root,COG3292@1|root,COG3023@2|Bacteria,COG3292@2|Bacteria,4NHTI@976|Bacteroidetes,1HZ0K@117743|Flavobacteriia,3ZNHV@59732|Chryseobacterium	976|Bacteroidetes	T	Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein.	-	-	-	-	-	-	-	-	-	-	-	-	CUB,Pep_M12B_propep,Reprolysin_5
DTH2_k127_8056240_6	504472.Slin_2803	5.621e-186	587.0	COG1454@1|root,COG1454@2|Bacteria,4PKHV@976|Bacteroidetes,47NV0@768503|Cytophagia	976|Bacteroidetes	C	Iron-containing alcohol dehydrogenase	-	-	1.1.3.48	ko:K19714	-	-	R11394	RC03427	ko00000,ko01000,ko01005	-	-	-	Fe-ADH
DTH2_k127_8056240_5	761193.Runsl_3570	1.219e-196	619.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,47MSW@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_8056240_43	926549.KI421517_gene1036	1.939e-20	97.0	2DZN5@1|root,33CRM@2|Bacteria,4NZFZ@976|Bacteroidetes,47T7Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8056240_48	485918.Cpin_3000	1.995e-06	50.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IT98@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
DTH2_k127_8056240_4	391596.PBAL39_10101	5.182e-208	671.0	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,1IQC3@117747|Sphingobacteriia	976|Bacteroidetes	L	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1,UvrD_C_2
DTH2_k127_8056240_46	1355368.JART01000008_gene1743	7.042e-12	70.0	COG0745@1|root,COG0745@2|Bacteria,1PFKD@1224|Proteobacteria,42TIQ@68525|delta/epsilon subdivisions,2YPWE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_8056240_32	1220534.B655_0067	8.331e-50	195.0	COG2203@1|root,arCOG06940@1|root,arCOG02361@2157|Archaea,arCOG06940@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg
DTH2_k127_8056240_40	925409.KI911562_gene810	1.488e-26	109.0	COG3530@1|root,COG3530@2|Bacteria,4NUSP@976|Bacteroidetes,1ITV9@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
DTH2_k127_8056240_21	1313421.JHBV01000029_gene2007	1.031e-78	271.0	2DBF0@1|root,2Z8VT@2|Bacteria,4NECW@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
DTH2_k127_8056240_11	755732.Fluta_1284	1.248e-141	476.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_8056240_23	743722.Sph21_3586	2.083e-66	235.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,1IRY3@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_8056240_3	926559.JoomaDRAFT_2682	4.33e-209	658.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia	976|Bacteroidetes	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
DTH2_k127_8056240_41	1185876.BN8_05067	3.078e-25	110.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,47RHB@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
DTH2_k127_8056240_27	153721.MYP_2760	2.27e-61	228.0	COG3146@1|root,COG3146@2|Bacteria,4NI7H@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB_like
DTH2_k127_8056240_30	679199.HMPREF9332_00867	4.09e-51	186.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,2FMA4@200643|Bacteroidia,1WDR5@1283313|Alloprevotella	976|Bacteroidetes	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
DTH2_k127_8056240_13	755732.Fluta_1925	9.831e-131	423.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1ICQK@117743|Flavobacteriia,2PBS2@246874|Cryomorphaceae	976|Bacteroidetes	F	DeoC/LacD family aldolase	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH2_k127_8056240_2	755732.Fluta_1926	3.999e-242	755.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia,2PBC6@246874|Cryomorphaceae	976|Bacteroidetes	C	Aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH2_k127_8056240_16	929556.Solca_2398	1.157e-109	365.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DTH2_k127_8056240_8	929556.Solca_2578	3.298e-178	574.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_8056240_44	886379.AEWI01000012_gene1061	1.476e-19	92.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,2FUKM@200643|Bacteroidia,3XK7E@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribonuclease P	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DTH2_k127_8056240_50	398720.MED217_14665	0.0004082	44.0	2BPFN@1|root,32I7W@2|Bacteria,4PE52@976|Bacteroidetes,1IEKF@117743|Flavobacteriia,2XKEY@283735|Leeuwenhoekiella	976|Bacteroidetes	S	30S ribosomal protein Thx	-	-	-	-	-	-	-	-	-	-	-	-	Thx
DTH2_k127_8056240_28	1358423.N180_13870	1.199e-59	215.0	COG0670@1|root,COG0670@2|Bacteria,4NMEV@976|Bacteroidetes,1J0DB@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
DTH2_k127_8056240_29	1313421.JHBV01000014_gene3914	5.396e-57	214.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_8056240_10	755732.Fluta_1300	1.28e-161	519.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia,2PAA5@246874|Cryomorphaceae	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_8056240_0	468059.AUHA01000002_gene1251	0.0	1136.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
DTH2_k127_8056240_45	1168034.FH5T_11845	6.789e-12	70.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_8056240_18	926692.AZYG01000096_gene1900	1.614e-106	363.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia	186801|Clostridia	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_8056240_9	1122605.KB893626_gene2729	9.108e-165	535.0	COG0457@1|root,COG0457@2|Bacteria,4PKJM@976|Bacteroidetes,1J0ZM@117747|Sphingobacteriia	976|Bacteroidetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
DTH2_k127_8056240_7	153721.MYP_188	3.311e-185	587.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,47MXQ@768503|Cytophagia	976|Bacteroidetes	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DTH2_k127_8056240_19	1517682.HW49_02985	1.211e-98	335.0	COG2937@1|root,COG2937@2|Bacteria,4PMFA@976|Bacteroidetes,2G0YT@200643|Bacteroidia	976|Bacteroidetes	I	Belongs to the GPAT DAPAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_8056240_34	471854.Dfer_5791	5.337e-41	159.0	298PT@1|root,2ZVU7@2|Bacteria,4NPTP@976|Bacteroidetes,47RY6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8056240_35	269798.CHU_2789	4.504e-38	153.0	2CFX6@1|root,32S2Q@2|Bacteria,4NTW8@976|Bacteroidetes,47VJ9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8056240_17	929556.Solca_4345	1.958e-108	357.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IQR9@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH2_k127_8134102_5	1453500.AT05_04560	5.196e-54	211.0	COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD,PKD,fn3
DTH2_k127_8134102_10	445961.IW15_10675	5.4e-09	68.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,3ZRCG@59732|Chryseobacterium	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8134102_11	1392489.JPOL01000003_gene5	2.753e-06	61.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
DTH2_k127_8134102_7	755732.Fluta_2019	7.07e-29	135.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4P1A1@976|Bacteroidetes	2|Bacteria	E	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,HYR,MAM,PKD,Peptidase_M43,Peptidase_S8,SprB,fn3
DTH2_k127_8134102_0	1122605.KB893631_gene3901	1.879e-219	685.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DTH2_k127_8134102_3	471854.Dfer_5066	2.273e-71	249.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DTH2_k127_8134102_9	700598.Niako_4532	2.271e-14	86.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IZJI@117747|Sphingobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8134102_6	1237149.C900_01862	9.939e-39	149.0	COG1309@1|root,COG2852@1|root,COG1309@2|Bacteria,COG2852@2|Bacteria,4NUSE@976|Bacteroidetes,47RNW@768503|Cytophagia	976|Bacteroidetes	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
DTH2_k127_8134102_1	1408433.JHXV01000007_gene2894	1.395e-191	603.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2PAJV@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_8134102_4	1042376.AFPK01000043_gene1015	2.033e-54	196.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1I29Z@117743|Flavobacteriia,406F0@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	F	Phosphoribosyl transferase domain	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
DTH2_k127_8134102_8	755732.Fluta_2595	4.963e-28	123.0	COG3047@1|root,COG3047@2|Bacteria,4NEAU@976|Bacteroidetes,1HYKC@117743|Flavobacteriia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_8134102_2	1408433.JHXV01000029_gene3086	6.65e-161	540.0	COG2911@1|root,COG3179@1|root,COG2911@2|Bacteria,COG3179@2|Bacteria,4NF8K@976|Bacteroidetes,1HYFJ@117743|Flavobacteriia,2PBIX@246874|Cryomorphaceae	976|Bacteroidetes	S	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH2_k127_8157388_27	1122225.AULQ01000005_gene2684	9.868e-28	117.0	2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,1I2I5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1705
DTH2_k127_8157388_0	269798.CHU_1442	1.619e-289	922.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_8157388_12	649349.Lbys_2650	1.556e-98	329.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,47JJ8@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
DTH2_k127_8157388_33	485917.Phep_1197	4.849e-12	70.0	2E4AG@1|root,33IJ2@2|Bacteria,4P9RI@976|Bacteroidetes,1IUJQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
DTH2_k127_8157388_22	1538644.KO02_15355	3.133e-48	177.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1ISE3@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
DTH2_k127_8157388_10	1239962.C943_04256	1.206e-118	391.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_8157388_18	269798.CHU_0208	9.131e-75	281.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
DTH2_k127_8157388_30	1121285.AUFK01000018_gene762	4.764e-15	81.0	COG2350@1|root,COG2350@2|Bacteria,4NR5W@976|Bacteroidetes,1I5PD@117743|Flavobacteriia,3ZURT@59732|Chryseobacterium	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8157388_31	1408433.JHXV01000012_gene3874	1.252e-14	86.0	COG4935@1|root,COG4935@2|Bacteria,4PI04@976|Bacteroidetes,1IG77@117743|Flavobacteriia,2PBN7@246874|Cryomorphaceae	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8157388_24	518766.Rmar_0035	9.555e-45	170.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH2_k127_8157388_5	1408473.JHXO01000009_gene3352	3.115e-163	543.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,2FM9F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8157388_19	926562.Oweho_0210	2.314e-74	270.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia,2PAR3@246874|Cryomorphaceae	976|Bacteroidetes	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH2_k127_8157388_6	1168034.FH5T_18950	1.584e-140	468.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
DTH2_k127_8157388_26	313606.M23134_05371	1.024e-29	135.0	COG0515@1|root,COG5263@1|root,COG0515@2|Bacteria,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,47PRU@768503|Cytophagia	976|Bacteroidetes	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_8157388_7	1185876.BN8_01665	9.816e-135	442.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
DTH2_k127_8157388_21	929703.KE386491_gene3815	6.961e-49	176.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,47QEV@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
DTH2_k127_8157388_13	1121904.ARBP01000009_gene4301	2.2e-95	321.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,47MCF@768503|Cytophagia	976|Bacteroidetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
DTH2_k127_8157388_8	926562.Oweho_1585	6.826e-134	445.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia,2PAPC@246874|Cryomorphaceae	976|Bacteroidetes	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DTH2_k127_8157388_15	926562.Oweho_1586	8.49e-89	299.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia,2PAR7@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH2_k127_8157388_23	153721.MYP_252	1.554e-46	175.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
DTH2_k127_8157388_16	1123248.KB893340_gene2662	1.12e-78	276.0	COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,1IQ1K@117747|Sphingobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_8157388_14	1121912.AUHD01000003_gene3099	1.961e-90	303.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1HXMN@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
DTH2_k127_8157388_28	487796.Flav2ADRAFT_0193	5.663e-20	95.0	COG0526@1|root,COG0526@2|Bacteria,4NS1W@976|Bacteroidetes,1I3EA@117743|Flavobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
DTH2_k127_8157388_29	1144313.PMI10_00931	9.33e-19	94.0	COG0810@1|root,COG0810@2|Bacteria,4PPSH@976|Bacteroidetes,1IKSQ@117743|Flavobacteriia,2P0BH@237|Flavobacterium	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8157388_2	1094466.KQS_12880	2.107e-246	765.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,2NTT1@237|Flavobacterium	976|Bacteroidetes	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH2_k127_8157388_20	468059.AUHA01000002_gene355	1.859e-51	188.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
DTH2_k127_8157388_1	929703.KE386491_gene2166	2.154e-252	781.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,47MTA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH2_k127_8157388_17	1408433.JHXV01000038_gene2198	4.654e-75	281.0	COG2885@1|root,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_8157388_34	338966.Ppro_0441	5.269e-09	68.0	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria,43SWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_8157388_11	1313421.JHBV01000029_gene1929	1.162e-104	345.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1IRUS@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_8157388_25	1124780.ANNU01000005_gene2358	6.141e-41	156.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,47QBK@768503|Cytophagia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
DTH2_k127_8157388_9	485918.Cpin_6488	4.773e-132	436.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,1IPRI@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Bacterial Fmu (Sun) eukaryotic nucleolar NOL1 Nop2p	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
DTH2_k127_8157388_4	1168034.FH5T_21745	4.364e-214	684.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_8157388_35	1233950.IW22_11350	9.954e-08	62.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,3ZPCK@59732|Chryseobacterium	976|Bacteroidetes	S	Metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
DTH2_k127_8157388_36	1249997.JHZW01000003_gene3688	0.0004951	51.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,1I0KC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DTH2_k127_8157388_3	762903.Pedsa_0857	2.082e-220	705.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH2_k127_8168330_9	926556.Echvi_3381	1.093e-05	58.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	fpp2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
DTH2_k127_8168330_3	926551.KB900738_gene104	3.059e-174	550.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1HWK5@117743|Flavobacteriia,1EQVJ@1016|Capnocytophaga	976|Bacteroidetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
DTH2_k127_8168330_4	313606.M23134_00734	7.124e-127	444.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
DTH2_k127_8168330_0	313606.M23134_08061	1.637e-200	651.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_8168330_5	153721.MYP_305	1.469e-98	326.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH2_k127_8168330_6	153721.MYP_3531	1.356e-76	276.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_8168330_8	1122931.AUAE01000005_gene3375	1.923e-39	157.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,2FMGW@200643|Bacteroidia,22WSS@171551|Porphyromonadaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_8168330_7	886379.AEWI01000064_gene2315	3.03e-72	253.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia,3XJ7Z@558415|Marinilabiliaceae	976|Bacteroidetes	S	Eukaryotic integral membrane protein (DUF1751)	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
DTH2_k127_8168330_1	1270196.JCKI01000002_gene38	2.753e-191	614.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH2_k127_8168330_2	1484460.JSWG01000006_gene3028	9.51e-176	617.0	COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3866@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
DTH2_k127_8172789_11	1210884.HG799462_gene7865	3.423e-07	61.0	2DSAR@1|root,33F9F@2|Bacteria,2J1A0@203682|Planctomycetes	1210884.HG799462_gene7865|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8172789_8	1408433.JHXV01000015_gene1728	4.613e-25	116.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia,2PAS1@246874|Cryomorphaceae	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_8172789_5	1408473.JHXO01000007_gene808	2.142e-78	299.0	COG0457@1|root,COG0457@2|Bacteria,4P45T@976|Bacteroidetes,2FYEG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8172789_3	1250006.JHZZ01000001_gene1250	1.96e-121	402.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia,3VVCB@52959|Polaribacter	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH2_k127_8172789_0	929556.Solca_1154	5.396e-209	658.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
DTH2_k127_8172789_2	880073.Calab_2100	8.651e-155	507.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
DTH2_k127_8172789_1	1453500.AT05_08630	1.065e-207	649.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_8172789_4	869213.JCM21142_73066	1.008e-96	327.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
DTH2_k127_8172789_9	1224136.AMFN01000002_gene216	4.607e-19	91.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S9GR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
DTH2_k127_8172789_6	153721.MYP_243	5.898e-74	274.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_8172789_7	1131812.JQMS01000001_gene1312	1.058e-72	251.0	COG1738@1|root,COG1738@2|Bacteria,4NNPU@976|Bacteroidetes,1I2GG@117743|Flavobacteriia,2NU67@237|Flavobacterium	976|Bacteroidetes	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
DTH2_k127_8172789_12	1341181.FLJC2902T_02360	0.0001865	51.0	COG3291@1|root,COG4886@1|root,COG5184@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria,COG5184@2|Bacteria,4NIM6@976|Bacteroidetes,1HX50@117743|Flavobacteriia,2NU2T@237|Flavobacterium	976|Bacteroidetes	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH2_k127_8172789_10	431947.PGN_1970	6.665e-15	83.0	COG1974@1|root,COG1974@2|Bacteria,4PKGW@976|Bacteroidetes,2FXSG@200643|Bacteroidia,2323F@171551|Porphyromonadaceae	976|Bacteroidetes	KT	cysteine-type peptidase activity	-	-	3.4.22.37	ko:K08589	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cleaved_Adhesin,DUF2436,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_8296331_2	929556.Solca_0910	1.838e-163	522.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH2_k127_8296331_17	1270196.JCKI01000002_gene494	5.833e-45	169.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH2_k127_8296331_20	1408813.AYMG01000039_gene2341	2.777e-28	129.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPAI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_8296331_22	575590.HMPREF0156_00944	1.021e-16	93.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA
DTH2_k127_8296331_15	869213.JCM21142_93878	2.096e-55	199.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
DTH2_k127_8296331_0	929556.Solca_1162	3.233e-219	686.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
DTH2_k127_8296331_14	709991.Odosp_3106	6.949e-60	214.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,2FM8F@200643|Bacteroidia,22XQ4@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
DTH2_k127_8296331_18	1313421.JHBV01000004_gene713	5.272e-40	153.0	2BY14@1|root,341GU@2|Bacteria,4P4NM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8296331_3	1341181.FLJC2902T_21590	1.926e-157	500.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia,2NSQA@237|Flavobacterium	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
DTH2_k127_8296331_1	1358423.N180_17290	6.573e-168	554.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,1IPVY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_8296331_5	929556.Solca_4417	3.797e-121	398.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1IRI6@117747|Sphingobacteriia	976|Bacteroidetes	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DTH2_k127_8296331_11	553175.POREN0001_0414	7.586e-82	279.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,22VV8@171551|Porphyromonadaceae	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
DTH2_k127_8296331_13	1120951.AUBG01000007_gene120	6.749e-71	250.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
DTH2_k127_8296331_4	929556.Solca_1244	1.557e-152	486.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH2_k127_8296331_27	886377.Murru_1700	2.121e-06	58.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	MORN_2
DTH2_k127_8296331_29	984262.SGRA_2889	0.0008495	51.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_8296331_21	153721.MYP_2634	7.88e-28	126.0	COG2374@1|root,COG2374@2|Bacteria,4NURG@976|Bacteroidetes,47RX0@768503|Cytophagia	976|Bacteroidetes	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
DTH2_k127_8296331_10	1313421.JHBV01000023_gene5122	2e-84	298.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1IP77@117747|Sphingobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
DTH2_k127_8296331_6	237368.SCABRO_01436	3.149e-112	377.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
DTH2_k127_8296331_19	1120966.AUBU01000001_gene1011	5.656e-30	126.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,47RVI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8296331_9	762903.Pedsa_0258	6.487e-86	289.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
DTH2_k127_8296331_7	1408433.JHXV01000021_gene1655	1.361e-91	307.0	COG4627@1|root,COG4627@2|Bacteria,4PP0V@976|Bacteroidetes,1IKE8@117743|Flavobacteriia,2PAIZ@246874|Cryomorphaceae	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH2_k127_8296331_12	385682.AFSL01000024_gene2069	2.424e-79	286.0	2CMNP@1|root,32SF6@2|Bacteria,4NSZE@976|Bacteroidetes,2G31M@200643|Bacteroidia,3XIU2@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8296331_25	391598.FBBAL38_12255	2.012e-10	72.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3,Flg_new,LRR_5,LTD
DTH2_k127_8296331_16	880071.Fleli_0838	4.444e-53	194.0	COG2885@1|root,COG2885@2|Bacteria,4NSJW@976|Bacteroidetes,47REJ@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_8296331_8	509635.N824_02770	7.536e-87	290.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DTH2_k127_8296331_23	755732.Fluta_0947	4.557e-15	86.0	2A7NQ@1|root,30WKT@2|Bacteria,4PA0D@976|Bacteroidetes,1IF21@117743|Flavobacteriia,2PBZY@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8296331_24	46681.XP_001735018.1	7.001e-15	84.0	COG2114@1|root,KOG0618@2759|Eukaryota	2759|Eukaryota	T	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PP2C
DTH2_k127_8302748_1	1121890.AUDO01000022_gene1171	9.669e-110	356.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1I16J@117743|Flavobacteriia,2NSWN@237|Flavobacterium	976|Bacteroidetes	P	permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DTH2_k127_8302748_0	1107311.Q767_08895	2.763e-131	421.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1HZHC@117743|Flavobacteriia,2NSSM@237|Flavobacterium	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
DTH2_k127_8302748_2	1150600.ADIARSV_3147	1.425e-41	157.0	COG0704@1|root,COG0704@2|Bacteria,4NNT5@976|Bacteroidetes,1ISF5@117747|Sphingobacteriia	976|Bacteroidetes	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
DTH2_k127_8305121_13	1408433.JHXV01000009_gene1334	1.131e-26	125.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8305121_0	1408433.JHXV01000017_gene1629	0.0	1101.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
DTH2_k127_8305121_12	1408433.JHXV01000017_gene1628	7.095e-33	132.0	290ZX@1|root,2ZNMM@2|Bacteria,4P891@976|Bacteroidetes,1ICSI@117743|Flavobacteriia,2PC01@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8305121_7	755732.Fluta_3556	6.925e-58	212.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8305121_4	1168034.FH5T_07035	2.849e-120	399.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,2FPNI@200643|Bacteroidia	976|Bacteroidetes	M	3-Deoxy-D-manno-octulosonic-acid transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
DTH2_k127_8305121_11	760192.Halhy_6283	3.224e-46	176.0	2EA9Q@1|root,334E4@2|Bacteria,4NX5I@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8305121_5	714943.Mucpa_5182	1.083e-112	368.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_8305121_9	929562.Emtol_2426	3.887e-48	180.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,47JSA@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH2_k127_8305121_8	1237149.C900_00122	1.249e-55	200.0	COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47Q3B@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_8305121_10	1519464.HY22_14020	9.703e-47	172.0	COG1846@1|root,COG1846@2|Bacteria,1FFDA@1090|Chlorobi	1090|Chlorobi	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
DTH2_k127_8305121_1	1453500.AT05_06550	0.0	1024.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_8305121_15	1227739.Hsw_3723	3.769e-17	89.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2,OmpA_membrane
DTH2_k127_8305121_2	468059.AUHA01000002_gene1347	3.637e-284	878.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IQ23@117747|Sphingobacteriia	976|Bacteroidetes	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_8305121_14	926562.Oweho_1422	9.251e-18	100.0	COG3291@1|root,COG3291@2|Bacteria,4PHXB@976|Bacteroidetes,1IBNK@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_8305121_3	869213.JCM21142_83275	1.248e-151	535.0	COG1345@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8305121_16	485918.Cpin_4506	2.886e-15	91.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,4NHWG@976|Bacteroidetes,1IRF4@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_8305121_6	1123248.KB893322_gene568	1.961e-61	240.0	COG1361@1|root,COG3291@1|root,COG4386@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,4NDZC@976|Bacteroidetes,1IV4S@117747|Sphingobacteriia	976|Bacteroidetes	M	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
DTH2_k127_8372587_16	153721.MYP_4062	1.822e-15	79.0	COG4733@1|root,COG4733@2|Bacteria,4NF53@976|Bacteroidetes,47MWJ@768503|Cytophagia	976|Bacteroidetes	S	SPTR Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8372587_5	755732.Fluta_1284	5.679e-127	432.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_8372587_3	468059.AUHA01000003_gene1685	7.323e-167	532.0	COG2271@1|root,COG2271@2|Bacteria,4NG3R@976|Bacteroidetes,1IW8Q@117747|Sphingobacteriia	976|Bacteroidetes	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
DTH2_k127_8372587_13	1408433.JHXV01000007_gene2897	5.113e-27	113.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1IMXN@117743|Flavobacteriia,2PB40@246874|Cryomorphaceae	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
DTH2_k127_8372587_10	1124780.ANNU01000005_gene2373	1.261e-90	307.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,47JJY@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH2_k127_8372587_15	1120965.AUBV01000004_gene678	7.66e-18	84.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,47SQ2@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
DTH2_k127_8372587_4	929703.KE386491_gene371	9.467e-131	448.0	COG4485@1|root,COG4485@2|Bacteria,4NUQF@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH2_k127_8372587_9	926549.KI421517_gene792	2.258e-108	355.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH2_k127_8372587_12	742727.HMPREF9447_03565	2.199e-46	170.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,2FT2Q@200643|Bacteroidia,4AQK2@815|Bacteroidaceae	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DTH2_k127_8372587_6	743722.Sph21_1062	2.624e-121	396.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
DTH2_k127_8372587_11	1173023.KE650771_gene598	6.619e-58	219.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1JK6S@1189|Stigonemataceae	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
DTH2_k127_8372587_7	755732.Fluta_2314	1.463e-114	376.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia,2PA55@246874|Cryomorphaceae	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_8372587_8	509635.N824_14215	1.187e-113	374.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
DTH2_k127_8372587_0	714943.Mucpa_3621	1.602e-206	660.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1IPH4@117747|Sphingobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	cap5D	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
DTH2_k127_8372587_2	1121481.AUAS01000011_gene5107	3.904e-168	538.0	COG0513@1|root,COG0513@2|Bacteria,4NHCA@976|Bacteroidetes,47MGW@768503|Cytophagia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DTH2_k127_8372587_1	1121912.AUHD01000017_gene3521	7.108e-169	546.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1HXJR@117743|Flavobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH2_k127_84068_0	1124780.ANNU01000038_gene197	0.0	1551.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH2_k127_84068_1	468059.AUHA01000003_gene1712	0.0	1054.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1INV9@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH2_k127_84068_4	1122931.AUAE01000008_gene4031	1.217e-170	546.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,2FMTV@200643|Bacteroidia,22X04@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_84068_5	929556.Solca_1890	2.866e-167	533.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_84068_11	926562.Oweho_1271	1.664e-25	107.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1I3YG@117743|Flavobacteriia,2PB6U@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
DTH2_k127_84068_10	688270.Celal_2428	1.544e-26	109.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia,1F9HI@104264|Cellulophaga	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DTH2_k127_84068_12	1408813.AYMG01000023_gene2022	2.657e-16	79.0	2AC5I@1|root,311PY@2|Bacteria,4PGIV@976|Bacteroidetes,1ITTN@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
DTH2_k127_84068_7	1408433.JHXV01000002_gene327	9.031e-142	456.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,1HX6U@117743|Flavobacteriia,2PA96@246874|Cryomorphaceae	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DTH2_k127_84068_13	760192.Halhy_3236	0.0002637	53.0	COG0810@1|root,COG0810@2|Bacteria,4P6JR@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
DTH2_k127_84068_9	1123248.KB893386_gene1827	4.874e-39	148.0	COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1ITN4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
DTH2_k127_84068_3	762903.Pedsa_3848	3.923e-187	588.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_84068_2	926549.KI421517_gene841	4.151e-212	665.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,47JKM@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH2_k127_84068_6	525257.HMPREF0204_12130	9.282e-161	512.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1I19J@117743|Flavobacteriia,3ZQE3@59732|Chryseobacterium	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH2_k127_84068_8	525257.HMPREF0204_12129	7.857e-101	331.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1HZ0I@117743|Flavobacteriia,3ZS2S@59732|Chryseobacterium	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
DTH2_k127_8485300_1	1515615.HQ41_04095	2.356e-257	800.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia,22WCA@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DTH2_k127_8485300_10	323259.Mhun_2840	1.313e-15	89.0	COG3291@1|root,arCOG02516@1|root,arCOG03264@1|root,arCOG03606@1|root,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG03264@2157|Archaea,arCOG03606@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF3344,PKD
DTH2_k127_8485300_8	926562.Oweho_2395	2.385e-44	167.0	COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,1IG88@117743|Flavobacteriia,2PB14@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_8485300_6	1121129.KB903360_gene3403	3.49e-85	290.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,2FN90@200643|Bacteroidia,22X8F@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
DTH2_k127_8485300_3	927658.AJUM01000034_gene432	4.286e-106	350.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,2FN7D@200643|Bacteroidia,3XJD4@558415|Marinilabiliaceae	976|Bacteroidetes	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
DTH2_k127_8485300_12	1122621.ATZA01000004_gene1157	3.486e-08	66.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes,1IRXG@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
DTH2_k127_8485300_5	97139.C824_04469	2.055e-99	347.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,36ERR@31979|Clostridiaceae	186801|Clostridia	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_8485300_9	1380384.JADN01000010_gene19	4.317e-28	128.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1HWNP@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DTH2_k127_8485300_4	411684.HPDFL43_01695	1.096e-104	351.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,2TVKU@28211|Alphaproteobacteria,43N4M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	D	ATPase of the PP-loop superfamily implicated in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,NAD_synthase,PAPS_reduct
DTH2_k127_8485300_2	1250006.JHZZ01000001_gene2284	9.74e-116	383.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,3VWNZ@52959|Polaribacter	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DTH2_k127_8485300_7	1453500.AT05_11140	5.994e-84	295.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8485300_11	1408433.JHXV01000005_gene2262	5.155e-12	77.0	2CA1R@1|root,32FVT@2|Bacteria,4PBTZ@976|Bacteroidetes,1I9V5@117743|Flavobacteriia,2PBA8@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
DTH2_k127_8485300_0	929556.Solca_2982	3.962e-316	977.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,1IPCI@117747|Sphingobacteriia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DTH2_k127_8497397_20	485918.Cpin_6537	1.084e-16	79.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8497397_18	99598.Cal7507_5339	1.875e-28	127.0	COG1216@1|root,COG3914@1|root,COG1216@2|Bacteria,COG3914@2|Bacteria,1GQBE@1117|Cyanobacteria,1HMG1@1161|Nostocales	1117|Cyanobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Glycos_transf_2
DTH2_k127_8497397_3	1121285.AUFK01000013_gene2050	9.377e-140	456.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1HXJV@117743|Flavobacteriia,3ZQC5@59732|Chryseobacterium	976|Bacteroidetes	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
DTH2_k127_8497397_6	1410666.JHXG01000007_gene2145	1.75e-103	344.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,2FN1F@200643|Bacteroidia	976|Bacteroidetes	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
DTH2_k127_8497397_10	391612.CY0110_11842	1.408e-80	276.0	COG0438@1|root,COG4627@1|root,COG0438@2|Bacteria,COG4627@2|Bacteria,1G1VE@1117|Cyanobacteria,3KIAJ@43988|Cyanothece	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_8497397_5	1550091.JROE01000009_gene257	2.485e-105	352.0	COG1442@1|root,COG1442@2|Bacteria,4NGMZ@976|Bacteroidetes,1IR89@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8497397_13	1121481.AUAS01000011_gene5139	2.215e-49	186.0	COG1216@1|root,COG1216@2|Bacteria,4NNIR@976|Bacteroidetes,47S78@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8497397_24	1120965.AUBV01000014_gene1183	5.531e-09	68.0	COG0438@1|root,COG0438@2|Bacteria,4NTGE@976|Bacteroidetes,47XCZ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_8497397_23	1120965.AUBV01000016_gene100	3.469e-09	67.0	COG3754@1|root,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	-	-	-	ko:K07272,ko:K20444	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_1,RgpF
DTH2_k127_8497397_0	929556.Solca_0511	1.468e-215	700.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IRAR@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
DTH2_k127_8497397_7	944479.JQLX01000015_gene17	3.92e-94	315.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,42WPQ@68525|delta/epsilon subdivisions,2WV8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8497397_14	880071.Fleli_1680	2.373e-48	179.0	COG0241@1|root,COG0241@2|Bacteria,4NNDD@976|Bacteroidetes,47QM8@768503|Cytophagia	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
DTH2_k127_8497397_11	1123373.ATXI01000008_gene1561	1.538e-65	231.0	COG1208@1|root,COG1208@2|Bacteria,2GI50@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
DTH2_k127_8497397_9	761193.Runsl_4187	3.45e-84	283.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,47KZ6@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
DTH2_k127_8497397_4	742725.HMPREF9450_01324	8.581e-122	398.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,2FMIF@200643|Bacteroidia,22V0M@171550|Rikenellaceae	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
DTH2_k127_8497397_15	929556.Solca_1872	2.815e-43	168.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
DTH2_k127_8497397_17	926562.Oweho_1587	1.415e-29	119.0	COG2329@1|root,COG2329@2|Bacteria,4PKDD@976|Bacteroidetes,1IJ84@117743|Flavobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
DTH2_k127_8497397_19	755732.Fluta_3165	4.165e-25	109.0	COG2050@1|root,COG2050@2|Bacteria,4P9RP@976|Bacteroidetes,1IE1G@117743|Flavobacteriia,2PC33@246874|Cryomorphaceae	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH2_k127_8497397_16	926562.Oweho_0983	7.905e-39	158.0	COG2867@1|root,COG4978@1|root,COG2867@2|Bacteria,COG4978@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	QU41_28450	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,Polyketide_cyc2
DTH2_k127_8497397_8	929703.KE386491_gene3346	7.759e-85	286.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DTH2_k127_8497397_1	525373.HMPREF0766_10718	3.401e-201	634.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DTH2_k127_8497397_12	1286632.P278_13830	1.691e-50	183.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1I1Z5@117743|Flavobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
DTH2_k127_8497397_21	1313301.AUGC01000008_gene515	1.657e-16	84.0	2EE99@1|root,3383P@2|Bacteria,4NWQD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
DTH2_k127_8497397_2	743722.Sph21_1449	4.162e-144	464.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_8497397_22	980584.AFPB01000015_gene567	9.593e-12	68.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,4069F@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
DTH2_k127_8510138_1	926562.Oweho_2705	6.164e-70	244.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia,2PATM@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
DTH2_k127_8510138_2	1123037.AUDE01000032_gene2267	2.3e-49	177.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
DTH2_k127_8510138_0	1123037.AUDE01000032_gene2265	1.758e-275	851.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia	976|Bacteroidetes	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_8510138_3	269798.CHU_3004	2.008e-26	123.0	COG1807@1|root,COG1807@2|Bacteria,4P3UD@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_858502_3	595460.RRSWK_06974	1.533e-44	173.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
DTH2_k127_858502_4	1358423.N180_19825	3.695e-17	91.0	COG0810@1|root,COG0810@2|Bacteria,4NWK2@976|Bacteroidetes,1IWQC@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_858502_2	143224.JQMD01000002_gene558	4.058e-66	236.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DTH2_k127_858502_1	1408433.JHXV01000012_gene3977	5.66e-100	352.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,1I4GV@117743|Flavobacteriia,2PBAJ@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_858502_0	435591.BDI_1269	8.724e-126	407.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FNIS@200643|Bacteroidia,22X8D@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATP-binding cassette protein, ChvD family	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
DTH2_k127_874685_0	485918.Cpin_4048	5.124e-103	340.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,1IQTJ@117747|Sphingobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_874685_1	643473.KB235930_gene3558	7.037e-72	259.0	COG2706@1|root,COG2931@1|root,COG3391@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1GQ7W@1117|Cyanobacteria,1HTNJ@1161|Nostocales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,FG-GAP
DTH2_k127_874685_4	1270196.JCKI01000012_gene3437	1.299e-12	70.0	COG2827@1|root,COG2827@2|Bacteria,4NV6N@976|Bacteroidetes,1IUQV@117747|Sphingobacteriia	976|Bacteroidetes	L	GIY-YIG catalytic domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_874685_2	755732.Fluta_1314	1.876e-24	120.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
DTH2_k127_874685_3	1042209.HK44_017335	1.246e-12	81.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1T53M@1236|Gammaproteobacteria,1YUJ6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
DTH2_k127_8752948_1	565033.GACE_1136	5.409e-84	283.0	COG0110@1|root,arCOG01848@2157|Archaea,2Y25E@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_8752948_2	290402.Cbei_2595	4.575e-58	210.0	COG2230@1|root,COG2230@2|Bacteria,1W2G1@1239|Firmicutes,24TRJ@186801|Clostridia,36Q9G@31979|Clostridiaceae	186801|Clostridia	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8752948_3	1356852.N008_04000	4.038e-54	193.0	COG1898@1|root,COG1898@2|Bacteria,4PKN3@976|Bacteroidetes,47RJ6@768503|Cytophagia	976|Bacteroidetes	M	WxcM-like, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
DTH2_k127_8752948_0	1296415.JACC01000060_gene861	1.979e-124	423.0	COG1361@1|root,COG2885@1|root,COG2931@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG2931@2|Bacteria,4NKK8@976|Bacteroidetes,1HYEG@117743|Flavobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8752948_4	1123248.KB893322_gene568	5.116e-11	76.0	COG1361@1|root,COG3291@1|root,COG4386@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,4NDZC@976|Bacteroidetes,1IV4S@117747|Sphingobacteriia	976|Bacteroidetes	M	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
DTH2_k127_8813143_9	1250232.JQNJ01000001_gene1662	8.306e-42	156.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded DNA-binding protein	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH2_k127_8813143_11	1123248.KB893386_gene1826	5.331e-37	143.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ITMD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH2_k127_8813143_7	755732.Fluta_4050	7.407e-74	265.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_8813143_4	755732.Fluta_0907	1.202e-105	369.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_8813143_5	1178825.ALIH01000013_gene557	1.488e-93	314.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1IJGW@117743|Flavobacteriia	976|Bacteroidetes	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
DTH2_k127_8813143_0	929556.Solca_1745	3.616e-256	798.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1IP6T@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
DTH2_k127_8813143_10	313595.P700755_001752	2.328e-40	160.0	COG2304@1|root,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,1IFZZ@117743|Flavobacteriia,4C41B@83612|Psychroflexus	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_8813143_16	1168289.AJKI01000003_gene2736	1.387e-05	56.0	COG1470@1|root,COG1470@2|Bacteria,4NGFF@976|Bacteroidetes,2FN5A@200643|Bacteroidia,3XJ0Y@558415|Marinilabiliaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_8813143_3	468059.AUHA01000003_gene1547	1.665e-110	362.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
DTH2_k127_8813143_1	1237149.C900_00764	3.15e-155	499.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
DTH2_k127_8813143_2	1123248.KB893319_gene4007	5.539e-117	383.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH2_k127_8813143_8	1202532.FF52_08987	5.087e-59	207.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1I20S@117743|Flavobacteriia,2NVWI@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
DTH2_k127_8813143_6	485917.Phep_3021	1.1e-80	275.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1IQWM@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
DTH2_k127_8813143_13	1453500.AT05_05250	1.454e-18	96.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CHU_C,PKD,Peptidase_S8,fn3
DTH2_k127_8813143_12	945713.IALB_1835	5.125e-33	140.0	COG2911@1|root,COG4935@1|root,COG2911@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,FlgD_ig,Kelch_4,PA,Peptidase_M36
DTH2_k127_8813143_14	313606.M23134_02095	2.576e-12	74.0	COG1649@1|root,COG3291@1|root,COG1649@2|Bacteria,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,47Y1M@768503|Cytophagia	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Sortilin-Vps10
DTH2_k127_8853546_6	1094466.KQS_09855	1.258e-28	118.0	COG2827@1|root,COG2827@2|Bacteria,4NUKY@976|Bacteroidetes,1II52@117743|Flavobacteriia,2NXVP@237|Flavobacterium	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_8853546_0	755732.Fluta_2924	2.441e-260	812.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia,2PAFZ@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
DTH2_k127_8853546_5	657309.BXY_01400	1.158e-35	154.0	COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,2FNR1@200643|Bacteroidia,4AKK3@815|Bacteroidaceae	976|Bacteroidetes	M	LysM domain	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
DTH2_k127_8853546_3	720554.Clocl_1029	9.135e-86	292.0	COG3021@1|root,COG3021@2|Bacteria,1UKTK@1239|Firmicutes,25G3G@186801|Clostridia,3WNK8@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846,Exo_endo_phos
DTH2_k127_8853546_7	869213.JCM21142_93407	2.584e-26	124.0	COG0515@1|root,COG0515@2|Bacteria	869213.JCM21142_93407|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8853546_4	1168034.FH5T_07980	1.397e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_8853546_9	1408813.AYMG01000019_gene1817	1.295e-06	60.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,1IT0V@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_8853546_1	714943.Mucpa_4144	7.523e-200	640.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_8853546_2	468059.AUHA01000003_gene1907	1.202e-111	368.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_8862317_1	1121889.AUDM01000005_gene1758	2.895e-06	52.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,2P01U@237|Flavobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
DTH2_k127_8862317_2	344747.PM8797T_03965	1.349e-05	57.0	COG2319@1|root,COG2319@2|Bacteria,2IXJX@203682|Planctomycetes	203682|Planctomycetes	C	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
DTH2_k127_8862317_0	388413.ALPR1_00680	2.875e-08	66.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Phytase-like
DTH2_k127_8880475_16	927658.AJUM01000047_gene2833	4.451e-36	137.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,2FNFZ@200643|Bacteroidia,3XJ9Y@558415|Marinilabiliaceae	976|Bacteroidetes	L	ABC transporter	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
DTH2_k127_8880475_13	1041142.ATTP01000021_gene175	1.242e-52	194.0	COG2520@1|root,COG2520@2|Bacteria,1PJK4@1224|Proteobacteria,2VB8G@28211|Alphaproteobacteria,4BHI1@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH2_k127_8880475_10	886379.AEWI01000012_gene1044	3.051e-65	231.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH2_k127_8880475_2	869213.JCM21142_288	3.447e-186	592.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,4NJWI@976|Bacteroidetes,47KMN@768503|Cytophagia	976|Bacteroidetes	MQ	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
DTH2_k127_8880475_11	742766.HMPREF9455_02117	1.635e-63	221.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,2FTXH@200643|Bacteroidia,22Y31@171551|Porphyromonadaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_8880475_8	926549.KI421517_gene3088	5.451e-88	304.0	COG3021@1|root,COG3021@2|Bacteria,4PKDH@976|Bacteroidetes	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_8880475_6	1453500.AT05_04305	6.504e-123	398.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1HXCX@117743|Flavobacteriia	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DTH2_k127_8880475_12	1233950.IW22_13950	1.755e-59	209.0	COG0561@1|root,COG0561@2|Bacteria,4PKY8@976|Bacteroidetes,1I1C5@117743|Flavobacteriia,3ZNHK@59732|Chryseobacterium	976|Bacteroidetes	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8880475_9	330214.NIDE0478	2.036e-79	269.0	COG0588@1|root,COG0588@2|Bacteria,3J118@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
DTH2_k127_8880475_15	1122194.AUHU01000002_gene2758	7.624e-41	168.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,1T460@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
DTH2_k127_8880475_14	1094466.KQS_10990	4.992e-41	164.0	COG0457@1|root,COG0457@2|Bacteria,4NGID@976|Bacteroidetes,1HX60@117743|Flavobacteriia,2NUSW@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8880475_4	926562.Oweho_0374	1.174e-162	518.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia,2PAGX@246874|Cryomorphaceae	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DTH2_k127_8880475_3	1406840.Q763_09995	5.01e-165	528.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia,2NSNP@237|Flavobacterium	976|Bacteroidetes	Q	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_8880475_1	1408473.JHXO01000004_gene166	1.501e-188	644.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
DTH2_k127_8880475_5	926562.Oweho_0721	1.314e-140	454.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia,2PACB@246874|Cryomorphaceae	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_8880475_0	1229276.DI53_0901	2.512e-245	763.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DTH2_k127_8880475_7	1123278.KB893615_gene5179	1.955e-90	306.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
DTH2_k127_8887162_0	1453500.AT05_00420	6.441e-130	436.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8887162_1	1236518.BAKP01000001_gene86	1.015e-13	81.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes,2FUCG@200643|Bacteroidia	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
DTH2_k127_8887162_2	1198452.Jab_2c04520	3.018e-09	58.0	COG3000@1|root,COG3000@2|Bacteria,1QSZU@1224|Proteobacteria,2VNKA@28216|Betaproteobacteria,4786V@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DTH2_k127_8893783_3	1137281.D778_01028	1.171e-46	192.0	COG1345@1|root,COG3291@1|root,COG4935@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia	976|Bacteroidetes	N	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CUB,LTD,fn3
DTH2_k127_8893783_5	1121889.AUDM01000008_gene766	6.681e-21	109.0	COG1345@1|root,COG3291@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
DTH2_k127_8893783_2	388413.ALPR1_12985	6.226e-99	326.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,47N3P@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DTH2_k127_8893783_0	485917.Phep_2329	9.467e-219	683.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1INZ7@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_8893783_4	755732.Fluta_0694	3.926e-45	176.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1ICQ4@117743|Flavobacteriia,2PBNE@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8893783_1	1313421.JHBV01000005_gene4509	4.635e-111	383.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPTT@117747|Sphingobacteriia	976|Bacteroidetes	M	OmpA MotB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_8893892_4	1123037.AUDE01000032_gene2260	1.692e-53	190.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1I1A5@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
DTH2_k127_8893892_5	926562.Oweho_2649	7.266e-35	136.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,2PB2C@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH2_k127_8893892_3	1123037.AUDE01000032_gene2262	9.573e-58	203.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia	976|Bacteroidetes	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
DTH2_k127_8893892_0	985255.APHJ01000019_gene532	2.309e-140	456.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia,2P62U@244698|Gillisia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DTH2_k127_8893892_1	1123037.AUDE01000032_gene2263	8.007e-101	342.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia	976|Bacteroidetes	O	assembly protein, SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_8893892_2	755732.Fluta_2087	9.24e-89	294.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1HWTU@117743|Flavobacteriia,2PAMD@246874|Cryomorphaceae	976|Bacteroidetes	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
DTH2_k127_8911913_13	1353276.JADR01000001_gene199	1.708e-12	70.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
DTH2_k127_8911913_5	616991.JPOO01000001_gene3551	1.47e-134	433.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,23FKH@178469|Arenibacter	976|Bacteroidetes	K	Sigma-70 region 3	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH2_k127_8911913_2	1380600.AUYN01000001_gene2495	1.883e-141	467.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1HXTJ@117743|Flavobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
DTH2_k127_8911913_3	1267211.KI669560_gene1210	2.636e-140	449.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_8911913_6	755732.Fluta_0377	4.7e-127	422.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia,2PAKB@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH2_k127_8911913_9	1380384.JADN01000008_gene1335	2.899e-89	300.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia	976|Bacteroidetes	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
DTH2_k127_8911913_4	929556.Solca_4271	1.304e-134	442.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_8911913_1	1408433.JHXV01000034_gene11	3.414e-170	551.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,1HXGH@117743|Flavobacteriia,2PA9N@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_8911913_8	755732.Fluta_2549	3.118e-103	346.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8911913_0	755732.Fluta_2550	6.958e-269	876.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,2PAHV@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DTH2_k127_8911913_7	1168034.FH5T_05685	3.549e-112	376.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,2FPVJ@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	porV	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8911913_10	945713.IALB_0281	3.6e-84	297.0	COG1468@1|root,COG1468@2|Bacteria	2|Bacteria	L	DNA catabolic process, exonucleolytic	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779,PDDEXK_1
DTH2_k127_8911913_11	755732.Fluta_0602	2.173e-48	196.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_3
DTH2_k127_8911913_14	1121288.AULL01000002_gene2092	2.478e-05	57.0	COG1345@1|root,COG3209@1|root,COG3291@1|root,COG4733@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,3ZRBK@59732|Chryseobacterium	976|Bacteroidetes	N	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
DTH2_k127_8911913_12	991.IW20_22165	1.104e-15	91.0	COG1361@1|root,COG1404@1|root,COG1572@1|root,COG2931@1|root,COG3391@1|root,COG4935@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NFMW@976|Bacteroidetes,1I06M@117743|Flavobacteriia,2NUXW@237|Flavobacterium	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CUB,DUF5011,Laminin_G_3,Peptidase_S8
DTH2_k127_8917101_1	385682.AFSL01000006_gene2308	8.73e-46	173.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,2FM5E@200643|Bacteroidia,3XIR2@558415|Marinilabiliaceae	976|Bacteroidetes	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
DTH2_k127_8917101_2	926549.KI421517_gene755	6.308e-14	81.0	COG1388@1|root,COG1388@2|Bacteria,4NPNH@976|Bacteroidetes,47Q7J@768503|Cytophagia	976|Bacteroidetes	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
DTH2_k127_8917101_3	1347342.BN863_20040	8.224e-07	59.0	COG5621@1|root,COG5621@2|Bacteria,4NWAB@976|Bacteroidetes,1I7FM@117743|Flavobacteriia	976|Bacteroidetes	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
DTH2_k127_8917101_0	714943.Mucpa_1462	8.292e-160	514.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
DTH2_k127_8935380_0	762903.Pedsa_0984	8.67e-239	761.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
DTH2_k127_8935380_1	468059.AUHA01000003_gene1863	1.634e-64	224.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1ISIR@117747|Sphingobacteriia	976|Bacteroidetes	T	GAF domain	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
DTH2_k127_8935380_2	755732.Fluta_1059	4.069e-56	199.0	2A94U@1|root,30Y94@2|Bacteria,4NP54@976|Bacteroidetes,1I2IQ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8935380_3	1237149.C900_03433	1.569e-15	78.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,47PYN@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM comF family protein	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
DTH2_k127_8954_1	1313421.JHBV01000026_gene449	8.622e-276	873.0	COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,1ISED@117747|Sphingobacteriia	976|Bacteroidetes	O	of the AAA class	-	-	-	-	-	-	-	-	-	-	-	-	AAA
DTH2_k127_8954_8	880071.Fleli_1373	6.225e-123	403.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_8954_31	1289135.A966_01908	1.483e-24	114.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
DTH2_k127_8954_23	153721.MYP_1019	3.741e-64	237.0	28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8954_13	880071.Fleli_3085	5.062e-106	356.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47RHW@768503|Cytophagia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_8954_19	1313421.JHBV01000016_gene5471	4.166e-68	241.0	COG1216@1|root,COG1216@2|Bacteria,4PMPA@976|Bacteroidetes,1IU1Y@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8954_30	1313301.AUGC01000013_gene1273	1.144e-35	150.0	COG0438@1|root,COG0438@2|Bacteria,4NK6N@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_8954_20	1313421.JHBV01000016_gene5469	7.257e-68	244.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_2,Glyphos_transf
DTH2_k127_8954_32	28072.Nos7524_0336	8.213e-22	106.0	COG2348@1|root,COG2348@2|Bacteria,1GGMU@1117|Cyanobacteria	1117|Cyanobacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8954_28	41431.PCC8801_1386	5.635e-41	161.0	COG0500@1|root,COG2226@2|Bacteria,1G37C@1117|Cyanobacteria,3KFS4@43988|Cyanothece	1117|Cyanobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DTH2_k127_8954_36	880073.Calab_2310	4.124e-19	99.0	COG0726@1|root,COG0726@2|Bacteria,2NQ5B@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_8954_15	1196322.A370_05136	1.658e-96	343.0	COG0037@1|root,COG0037@2|Bacteria,1V1S0@1239|Firmicutes,24BSC@186801|Clostridia,36GC2@31979|Clostridiaceae	186801|Clostridia	D	tRNA processing	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8954_34	318464.IO99_14340	2.865e-20	104.0	COG2244@1|root,COG2244@2|Bacteria,1V8VR@1239|Firmicutes,24BD7@186801|Clostridia,36EVG@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_8954_12	1124780.ANNU01000028_gene950	3.993e-112	369.0	COG1682@1|root,COG1682@2|Bacteria,4NF36@976|Bacteroidetes,47NFE@768503|Cytophagia	976|Bacteroidetes	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
DTH2_k127_8954_24	1469607.KK073768_gene3008	9.126e-61	226.0	COG0438@1|root,COG0438@2|Bacteria,1GBG7@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
DTH2_k127_8954_11	1094980.Mpsy_2369	9.338e-114	373.0	COG1089@1|root,arCOG01373@2157|Archaea,2Y39G@28890|Euryarchaeota,2NAJT@224756|Methanomicrobia	224756|Methanomicrobia	M	RmlD substrate binding domain	-	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_8954_26	1472716.KBK24_0124015	4.152e-48	179.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,2VR8A@28216|Betaproteobacteria,1K6UC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
DTH2_k127_8954_2	456442.Mboo_1758	7.511e-208	652.0	COG0500@1|root,arCOG02702@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH2_k127_8954_38	697303.Thewi_0577	6.001e-14	81.0	COG2519@1|root,COG2519@2|Bacteria,1V5X7@1239|Firmicutes,24IER@186801|Clostridia,42GEW@68295|Thermoanaerobacterales	186801|Clostridia	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH2_k127_8954_10	269798.CHU_0848	4.592e-116	385.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47JN7@768503|Cytophagia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	rfbB	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
DTH2_k127_8954_4	1279009.ADICEAN_03694	1.045e-153	491.0	COG0451@1|root,COG0451@2|Bacteria,4NKVH@976|Bacteroidetes,47TKC@768503|Cytophagia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH2_k127_8954_18	1121373.KB903624_gene2394	2.171e-82	283.0	COG2520@1|root,COG2520@2|Bacteria,4NVH3@976|Bacteroidetes,47XWB@768503|Cytophagia	976|Bacteroidetes	J	Vibrio cholerae RfbT protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH2_k127_8954_21	98439.AJLL01000098_gene1929	9.155e-66	236.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8954_22	1121897.AUGO01000009_gene2909	2.23e-65	228.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1I1CS@117743|Flavobacteriia,2NTYS@237|Flavobacterium	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DTH2_k127_8954_0	153721.MYP_2367	0.0	1087.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,47M8U@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DTH2_k127_8954_17	1313421.JHBV01000031_gene1447	2.305e-87	303.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes	976|Bacteroidetes	Q	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
DTH2_k127_8954_29	378806.STAUR_8057	3.452e-36	161.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,43BZJ@68525|delta/epsilon subdivisions,2X7AB@28221|Deltaproteobacteria,2YXY7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8954_6	1484460.JSWG01000006_gene3028	2.759e-133	480.0	COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3866@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Laminin_G_3,Lipase_GDSL_2,fn3
DTH2_k127_8954_33	1453500.AT05_04480	4.916e-21	111.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,fn3
DTH2_k127_8954_9	700598.Niako_0938	5.858e-118	386.0	COG3000@1|root,COG3000@2|Bacteria,4NI60@976|Bacteroidetes,1IQSK@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DTH2_k127_8954_35	1196322.A370_05870	9.416e-20	102.0	COG2273@1|root,COG3250@1|root,COG2273@2|Bacteria,COG3250@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia	186801|Clostridia	G	family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CW_binding_1,DUF1533,F5_F8_type_C,Glyco_hydro_16,SLH
DTH2_k127_8954_37	366602.Caul_4809	2.191e-14	84.0	2EYUR@1|root,33S1X@2|Bacteria,1NSGH@1224|Proteobacteria,2UPVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8954_7	1484460.JSWG01000009_gene182	8.65e-125	414.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
DTH2_k127_8954_3	1121904.ARBP01000003_gene6450	1.467e-185	600.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
DTH2_k127_8954_16	153721.MYP_243	2.568e-89	314.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_8954_39	1453500.AT05_09485	4.259e-09	62.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
DTH2_k127_8954_14	761193.Runsl_3684	7.771e-99	328.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DTH2_k127_8954_27	1237149.C900_02393	3.893e-41	163.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
DTH2_k127_8954_25	1123276.KB893290_gene5346	8.798e-49	184.0	COG1778@1|root,COG1778@2|Bacteria,4NMFZ@976|Bacteroidetes,47PAE@768503|Cytophagia	976|Bacteroidetes	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	-
DTH2_k127_8954_5	761193.Runsl_0202	8.653e-153	488.0	COG0176@1|root,COG2905@1|root,COG0176@2|Bacteria,COG2905@2|Bacteria,4NIUX@976|Bacteroidetes,47KKQ@768503|Cytophagia	976|Bacteroidetes	GT	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,TAL_FSA
DTH2_k127_8954_40	1121898.Q766_07050	6.697e-06	56.0	COG1629@1|root,COG1629@2|Bacteria,4PCUZ@976|Bacteroidetes,1I7RI@117743|Flavobacteriia,2NY1B@237|Flavobacterium	976|Bacteroidetes	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
DTH2_k127_8954_41	1408433.JHXV01000019_gene1976	2.242e-05	48.0	COG3693@1|root,COG3693@2|Bacteria,4PPN9@976|Bacteroidetes,1I52M@117743|Flavobacteriia,2PBV1@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8964352_3	945713.IALB_1822	2.321e-69	264.0	COG1470@1|root,COG1572@1|root,COG2911@1|root,COG3391@1|root,COG4412@1|root,COG1470@2|Bacteria,COG1572@2|Bacteria,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	mxcI	-	3.4.21.50	ko:K01337,ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CarboxypepD_reg,DUF1929,F5_F8_type_C,FlgD_ig
DTH2_k127_8964352_6	1313421.JHBV01000004_gene763	1.217e-25	124.0	COG4935@1|root,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes,1IYMI@117747|Sphingobacteriia	976|Bacteroidetes	O	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8964352_1	485918.Cpin_2595	5.514e-119	390.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
DTH2_k127_8964352_0	700598.Niako_5173	1.264e-124	406.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1IZDH@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_8964352_2	929562.Emtol_2945	1.495e-117	391.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,47N0I@768503|Cytophagia	976|Bacteroidetes	M	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
DTH2_k127_8964352_5	1250232.JQNJ01000001_gene3081	2.677e-34	144.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DTH2_k127_8964352_4	984262.SGRA_3314	2.169e-52	206.0	COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes	976|Bacteroidetes	S	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8981918_10	537011.PREVCOP_04391	3.77e-06	49.0	COG3392@1|root,COG3392@2|Bacteria	2|Bacteria	L	D12 class N6 adenine-specific DNA methyltransferase	fokIM	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12,N6_N4_Mtase
DTH2_k127_8981918_3	1250005.PHEL85_0617	9.139e-59	219.0	COG3886@1|root,COG3886@2|Bacteria,4NSXE@976|Bacteroidetes,1I7GS@117743|Flavobacteriia	976|Bacteroidetes	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HA,PLDc_2
DTH2_k127_8981918_8	1349785.BAUG01000072_gene2668	3.354e-22	97.0	COG3655@1|root,COG3655@2|Bacteria,4NVSP@976|Bacteroidetes,1I5EX@117743|Flavobacteriia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
DTH2_k127_8981918_7	1048983.EL17_00210	2.222e-25	109.0	2E4AP@1|root,32Z6C@2|Bacteria,4NWDP@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8981918_5	755732.Fluta_2488	5.711e-53	202.0	COG4733@1|root,COG4935@1|root,COG4733@2|Bacteria,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8981918_1	926569.ANT_29930	1.509e-92	311.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
DTH2_k127_8981918_6	694427.Palpr_0445	4.625e-46	172.0	COG0664@1|root,COG0664@2|Bacteria,4NSMK@976|Bacteroidetes,2FSMY@200643|Bacteroidia,231UJ@171551|Porphyromonadaceae	976|Bacteroidetes	T	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
DTH2_k127_8981918_4	1296416.JACB01000057_gene1486	5.13e-58	204.0	COG4682@1|root,COG4682@2|Bacteria,4NPA4@976|Bacteroidetes,1I200@117743|Flavobacteriia,2YH8P@290174|Aquimarina	976|Bacteroidetes	S	yiaA/B two helix domain	-	-	-	-	-	-	-	-	-	-	-	-	YiaAB
DTH2_k127_8981918_2	686340.Metal_3155	7.503e-68	240.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales	135618|Methylococcales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
DTH2_k127_8981918_0	269798.CHU_1886	4.123e-241	753.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	CP_0318	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
DTH2_k127_8981918_9	1237149.C900_02686	1.265e-11	64.0	COG1643@1|root,COG1643@2|Bacteria,4NFJ7@976|Bacteroidetes,47KRZ@768503|Cytophagia	976|Bacteroidetes	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
DTH2_k127_8985397_0	1237149.C900_02412	1.96e-315	981.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,47MMN@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_8985397_10	1120951.AUBG01000010_gene1876	9.852e-82	295.0	COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,1HY9C@117743|Flavobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8985397_13	755732.Fluta_3718	1.559e-39	152.0	2BFVS@1|root,32WJ0@2|Bacteria,4PGMC@976|Bacteroidetes,1IFB5@117743|Flavobacteriia,2PC3U@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8985397_8	485918.Cpin_1031	8.529e-138	445.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_8985397_1	1519464.HY22_03410	4.851e-266	831.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1FDT3@1090|Chlorobi	1090|Chlorobi	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH2_k127_8985397_14	700598.Niako_7211	2.482e-39	149.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH2_k127_8985397_9	700598.Niako_7212	8.773e-82	276.0	COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,1IQCF@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH2_k127_8985397_16	1121875.KB907547_gene3142	8.439e-35	138.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH2_k127_8985397_5	700598.Niako_7214	5.578e-175	554.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
DTH2_k127_8985397_6	700598.Niako_7215	1.626e-163	521.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1INP9@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH2_k127_8985397_11	700598.Niako_7216	1.593e-67	233.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
DTH2_k127_8985397_12	700598.Niako_7217	1.512e-47	176.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH2_k127_8985397_15	700598.Niako_7218	1.182e-38	146.0	COG0713@1|root,COG0713@2|Bacteria,4NSR8@976|Bacteroidetes,1ITB0@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH2_k127_8985397_2	700598.Niako_7219	1.994e-249	785.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQWT@117747|Sphingobacteriia	976|Bacteroidetes	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH2_k127_8985397_19	313603.FB2170_07989	7.498e-09	62.0	2EDMN@1|root,337HG@2|Bacteria,4NWVI@976|Bacteroidetes,1I9SP@117743|Flavobacteriia	976|Bacteroidetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
DTH2_k127_8985397_4	700598.Niako_7220	3.809e-217	683.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IR24@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
DTH2_k127_8985397_7	700598.Niako_7221	2.199e-160	518.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH2_k127_8985397_17	700598.Niako_7222	2.659e-34	136.0	2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8985397_3	1408433.JHXV01000027_gene3728	9.117e-248	810.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_8985397_18	758.BBIX01000003_gene46	3.929e-09	57.0	COG0759@1|root,COG0759@2|Bacteria,1QKA6@1224|Proteobacteria,1TIDP@1236|Gammaproteobacteria,1YAFC@135625|Pasteurellales	135625|Pasteurellales	S	Haemolytic	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DTH2_k127_902606_0	1270196.JCKI01000005_gene3154	6.707e-109	357.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_902606_1	1121859.KB890738_gene3232	2.156e-80	274.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,47JWX@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DTH2_k127_902606_2	1408473.JHXO01000010_gene3757	6.63e-62	220.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,2FS76@200643|Bacteroidia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DTH2_k127_9036778_35	1358423.N180_18515	5.728e-29	121.0	COG0824@1|root,COG0824@2|Bacteria,4NQ3I@976|Bacteroidetes,1ITE5@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_9036778_16	391587.KAOT1_18277	4.492e-97	327.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1HWSU@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH2_k127_9036778_9	509635.N824_13185	1.213e-151	482.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IPV3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_9036778_41	1123277.KB893173_gene1882	3.142e-05	55.0	28Q42@1|root,2ZCME@2|Bacteria,4NMXP@976|Bacteroidetes,47PFS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9036778_3	1434325.AZQN01000001_gene493	2.209e-222	715.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH2_k127_9036778_15	1380600.AUYN01000001_gene2927	9.652e-100	336.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1HXU5@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
DTH2_k127_9036778_27	1121904.ARBP01000015_gene260	1.465e-51	194.0	COG1994@1|root,COG1994@2|Bacteria,4NRNR@976|Bacteroidetes,47UP8@768503|Cytophagia	976|Bacteroidetes	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9036778_1	929556.Solca_0665	1.13e-246	768.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
DTH2_k127_9036778_22	153721.MYP_2168	1.638e-57	213.0	COG3842@1|root,COG3842@2|Bacteria,4NEZ6@976|Bacteroidetes,47N5M@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the ABC transporter superfamily	fbpC2	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
DTH2_k127_9036778_37	925409.KI911562_gene1620	4.872e-22	106.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_9036778_12	873517.HMPREF1977_0073	3.778e-106	354.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia,1ERQA@1016|Capnocytophaga	976|Bacteroidetes	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH2_k127_9036778_23	1453500.AT05_00835	2.488e-53	189.0	COG1145@1|root,COG1145@2|Bacteria,4NNF9@976|Bacteroidetes,1I1ZJ@117743|Flavobacteriia	976|Bacteroidetes	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
DTH2_k127_9036778_14	1279009.ADICEAN_01424	4.644e-101	344.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
DTH2_k127_9036778_7	926549.KI421517_gene471	1.527e-171	557.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH2_k127_9036778_11	1313421.JHBV01000039_gene2658	1.587e-106	365.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,CarboxypepD_reg,ChW,Cu-oxidase_2,DUF4842,Polysacc_deac_1,SLH
DTH2_k127_9036778_34	1121373.KB903621_gene1796	7.618e-30	122.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
DTH2_k127_9036778_18	1408473.JHXO01000001_gene1964	2.331e-89	308.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
DTH2_k127_9036778_29	1341181.FLJC2902T_05870	3.35e-39	150.0	COG2010@1|root,COG2010@2|Bacteria,4NEQA@976|Bacteroidetes,1IEM4@117743|Flavobacteriia,2NVYE@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
DTH2_k127_9036778_13	592029.DDD_2469	8.081e-103	354.0	COG4409@1|root,COG4409@2|Bacteria,4NZX2@976|Bacteroidetes	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9036778_2	755732.Fluta_0001	9.009e-233	728.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1HX45@117743|Flavobacteriia,2PAFX@246874|Cryomorphaceae	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DTH2_k127_9036778_10	1121899.Q764_01155	6.364e-109	361.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1HZAE@117743|Flavobacteriia,2NT79@237|Flavobacterium	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
DTH2_k127_9036778_33	1123277.KB893172_gene958	1.133e-32	136.0	COG0737@1|root,COG0737@2|Bacteria,4NR6D@976|Bacteroidetes,47MWV@768503|Cytophagia	976|Bacteroidetes	F	5'-nucleotidase, C-terminal domain	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
DTH2_k127_9036778_28	1408813.AYMG01000019_gene1778	2.868e-44	164.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IT5E@117747|Sphingobacteriia	976|Bacteroidetes	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_9036778_8	1453500.AT05_09530	8.172e-168	536.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_9036778_4	1356852.N008_04010	3.203e-218	683.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH2_k127_9036778_6	929703.KE386491_gene695	2.428e-187	587.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_9036778_39	1166018.FAES_1628	1.305e-06	57.0	2CXY2@1|root,32WVG@2|Bacteria,4NU8N@976|Bacteroidetes,47W2M@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9036778_36	1237149.C900_02851	3.415e-23	101.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,47RW5@768503|Cytophagia	976|Bacteroidetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
DTH2_k127_9036778_24	509191.AEDB02000048_gene4667	6.072e-53	192.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,24J7S@186801|Clostridia,3WIWY@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
DTH2_k127_9036778_31	1313421.JHBV01000032_gene1622	5e-35	146.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,CBM_6,CHU_C,PKD,SprB,fn3
DTH2_k127_9036778_21	1358423.N180_19995	1.921e-61	241.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1IPPI@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Signal transduction histidine kinase, internal region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,Reg_prop,Y_Y_Y
DTH2_k127_9036778_26	1454007.JAUG01000022_gene1246	6.954e-52	192.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_9036778_0	929556.Solca_1443	1.332e-252	798.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1IQ4I@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DTH2_k127_9036778_19	1123276.KB893313_gene3919	1.309e-82	280.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,47KMH@768503|Cytophagia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
DTH2_k127_9036778_5	1519464.HY22_08950	2.252e-206	665.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_9036778_20	1313421.JHBV01000033_gene2371	5.738e-64	237.0	COG1807@1|root,COG1807@2|Bacteria,4P68Z@976|Bacteroidetes	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_9036778_17	153721.MYP_243	1.188e-91	326.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_9036778_25	515635.Dtur_1285	6.174e-52	202.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
DTH2_k127_9036778_32	1121373.KB903641_gene3705	9.565e-33	142.0	2F2AF@1|root,33V8E@2|Bacteria,4P2D9@976|Bacteroidetes,47USP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9036778_30	1408433.JHXV01000005_gene2517	5.083e-39	164.0	2BJHF@1|root,32DUB@2|Bacteria,4P9RZ@976|Bacteroidetes,1ICNC@117743|Flavobacteriia,2PB7V@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9036778_38	1121957.ATVL01000014_gene1421	6.891e-22	99.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
DTH2_k127_9079017_1	929703.KE386491_gene3903	3.23e-156	509.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
DTH2_k127_9079017_4	1492738.FEM21_25060	1.372e-55	206.0	COG1266@1|root,COG1266@2|Bacteria,4NFKV@976|Bacteroidetes,1HY21@117743|Flavobacteriia,2NTMD@237|Flavobacterium	976|Bacteroidetes	S	Abortive phage infection protein	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DTH2_k127_9079017_8	1121101.HMPREF1532_02409	7.128e-09	65.0	2E6TM@1|root,331DG@2|Bacteria,4NYW8@976|Bacteroidetes,2FPEV@200643|Bacteroidia,4APRK@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
DTH2_k127_9079017_3	929562.Emtol_0904	2.59e-61	218.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,47PEP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
DTH2_k127_9079017_2	929703.KE386491_gene175	1.04e-61	221.0	COG3025@1|root,COG3025@2|Bacteria,4NM6K@976|Bacteroidetes,47PAH@768503|Cytophagia	976|Bacteroidetes	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH2_k127_9079017_6	929703.KE386491_gene174	9.116e-18	89.0	COG3209@1|root,COG3209@2|Bacteria,4P5T8@976|Bacteroidetes,47W80@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9079017_5	1313421.JHBV01000046_gene291	9.209e-23	103.0	2DGVM@1|root,2ZXFN@2|Bacteria,4P8FH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9079017_0	1122179.KB890435_gene931	1.506e-208	672.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH2_k127_9079017_9	391603.FBALC1_04002	3.772e-05	55.0	COG3386@1|root,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes,1IJ7K@117743|Flavobacteriia	976|Bacteroidetes	G	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9079017_7	926562.Oweho_2070	1.279e-12	74.0	COG1520@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4PI0E@976|Bacteroidetes,1IN8R@117743|Flavobacteriia,2PB6P@246874|Cryomorphaceae	976|Bacteroidetes	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR
DTH2_k127_9168254_7	755732.Fluta_4050	3.676e-89	310.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_9168254_15	1408433.JHXV01000014_gene3681	2.537e-15	82.0	COG2849@1|root,COG2849@2|Bacteria,4PC8C@976|Bacteroidetes,1IMSS@117743|Flavobacteriia,2PC0R@246874|Cryomorphaceae	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9168254_5	391598.FBBAL38_07665	1.108e-135	439.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1HWY7@117743|Flavobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH2_k127_9168254_4	525373.HMPREF0766_10844	9.5e-145	466.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1IQMY@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_9168254_6	509635.N824_13935	1.173e-89	309.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes,1IPAQ@117747|Sphingobacteriia	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DTH2_k127_9168254_14	714943.Mucpa_4195	2.882e-22	99.0	COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,1IU0B@117747|Sphingobacteriia	976|Bacteroidetes	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
DTH2_k127_9168254_3	1237149.C900_03447	1.109e-205	660.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
DTH2_k127_9168254_10	153721.MYP_4660	1.033e-59	214.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_9168254_9	1121957.ATVL01000006_gene3010	1.557e-60	222.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DTH2_k127_9168254_2	1227739.Hsw_3426	8.802e-211	675.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_9168254_11	743722.Sph21_0329	5.946e-51	183.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1ITFK@117747|Sphingobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
DTH2_k127_9168254_8	1408473.JHXO01000010_gene3770	2.821e-63	229.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,2G38E@200643|Bacteroidia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
DTH2_k127_9168254_12	1120965.AUBV01000017_gene160	2.697e-49	184.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9168254_0	929703.KE386491_gene438	1.216e-306	949.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47JMW@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH2_k127_9168254_13	1443665.JACA01000012_gene1158	5.414e-44	165.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia,2YJ12@290174|Aquimarina	976|Bacteroidetes	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DTH2_k127_9168254_1	700598.Niako_6196	2.531e-298	930.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH2_k127_9175992_18	457396.CSBG_00492	2.119e-43	168.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_9175992_22	1168034.FH5T_04905	1.51e-28	126.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,2FT4P@200643|Bacteroidia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
DTH2_k127_9175992_24	457396.CSBG_00491	1.337e-25	118.0	COG2348@1|root,COG2348@2|Bacteria,1V67I@1239|Firmicutes,24FI6@186801|Clostridia,36HXS@31979|Clostridiaceae	186801|Clostridia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
DTH2_k127_9175992_11	326298.Suden_1419	1.479e-98	334.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42UBA@68525|delta/epsilon subdivisions,2YQIM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
DTH2_k127_9175992_25	1034943.BN1094_00510	5.071e-25	114.0	COG1215@1|root,COG1215@2|Bacteria,1QVTJ@1224|Proteobacteria,1T5HP@1236|Gammaproteobacteria,1JF2C@118969|Legionellales	118969|Legionellales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_9175992_17	864702.OsccyDRAFT_4934	8.774e-50	190.0	COG1216@1|root,COG1216@2|Bacteria,1G4RU@1117|Cyanobacteria,1HH4K@1150|Oscillatoriales	1117|Cyanobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_9175992_8	1270196.JCKI01000001_gene4061	1.16e-134	435.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes	976|Bacteroidetes	O	Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH2_k127_9175992_26	1170562.Cal6303_2758	1.736e-14	85.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1GITD@1117|Cyanobacteria,1HRB3@1161|Nostocales	1117|Cyanobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
DTH2_k127_9175992_16	1121904.ARBP01000005_gene4663	1.485e-52	188.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,47PQ5@768503|Cytophagia	976|Bacteroidetes	H	PFAM 6-pyruvoyl tetrahydropterin synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_9175992_19	1121904.ARBP01000004_gene1006	1.418e-39	151.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,47PP3@768503|Cytophagia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
DTH2_k127_9175992_0	1168289.AJKI01000042_gene3710	1.084e-285	887.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,3XJ00@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
DTH2_k127_9175992_15	1148.1651934	4.539e-55	198.0	COG3542@1|root,COG3542@2|Bacteria,1G6JR@1117|Cyanobacteria,1H65M@1142|Synechocystis	1117|Cyanobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
DTH2_k127_9175992_4	929556.Solca_2328	7.152e-164	523.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH2_k127_9175992_2	926549.KI421517_gene374	6.713e-208	661.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,47KR9@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_9175992_10	1122621.ATZA01000010_gene208	4.209e-111	375.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
DTH2_k127_9175992_12	1408433.JHXV01000026_gene3043	7.252e-98	326.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IMQP@117743|Flavobacteriia,2PBFH@246874|Cryomorphaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
DTH2_k127_9175992_20	269798.CHU_2634	5.787e-34	133.0	COG0607@1|root,COG0607@2|Bacteria,4NRFK@976|Bacteroidetes,47RKB@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	naoX	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_9175992_13	755732.Fluta_0193	5.057e-75	257.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,1IISJ@117743|Flavobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH2_k127_9175992_28	391603.FBALC1_10577	7.692e-06	57.0	KOG3539@1|root,32TPV@2|Bacteria,4NMI6@976|Bacteroidetes,1I1I5@117743|Flavobacteriia	976|Bacteroidetes	S	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
DTH2_k127_9175992_6	1094466.KQS_13210	1.154e-146	476.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia,2NSMP@237|Flavobacterium	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DTH2_k127_9175992_27	929556.Solca_3438	3.048e-07	62.0	COG2913@1|root,COG2913@2|Bacteria,4NP4N@976|Bacteroidetes,1IUMP@117747|Sphingobacteriia	976|Bacteroidetes	J	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476,SmpA_OmlA
DTH2_k127_9175992_23	485917.Phep_1549	2.878e-26	113.0	COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1ITGX@117747|Sphingobacteriia	976|Bacteroidetes	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
DTH2_k127_9175992_1	755732.Fluta_3624	2.111e-257	803.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia,2PA7A@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
DTH2_k127_9175992_5	903818.KI912268_gene647	6.036e-159	515.0	COG1012@1|root,COG1012@2|Bacteria,3Y3Z0@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DTH2_k127_9175992_7	485917.Phep_3006	5.041e-143	460.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,1IQIA@117747|Sphingobacteriia	976|Bacteroidetes	C	potassium channel beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH2_k127_9175992_9	1408433.JHXV01000001_gene1065	7.136e-115	381.0	COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,1I0MK@117743|Flavobacteriia,2PBH8@246874|Cryomorphaceae	976|Bacteroidetes	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
DTH2_k127_9175992_21	1535422.ND16A_2807	5.496e-29	121.0	COG0454@1|root,COG0456@2|Bacteria,1R407@1224|Proteobacteria,1RPJ2@1236|Gammaproteobacteria,2Q5NJ@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Putative thioesterase (yiiD_Cterm)	yiiD	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
DTH2_k127_9175992_14	1408813.AYMG01000007_gene4279	3.594e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1INYP@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH2_k127_9175992_3	391587.KAOT1_07863	3.225e-177	566.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,1HXI7@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
DTH2_k127_9267023_14	376686.Fjoh_4051	3.777e-34	151.0	COG2911@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2P0KB@237|Flavobacterium	976|Bacteroidetes	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_9267023_9	1237149.C900_05299	7.252e-55	200.0	COG1073@1|root,COG1073@2|Bacteria,4NP3H@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
DTH2_k127_9267023_2	1218108.KB908291_gene923	1.407e-124	402.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_9267023_12	234267.Acid_0626	8.386e-48	188.0	COG1470@1|root,COG2373@1|root,COG2931@1|root,COG3391@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria,3Y49I@57723|Acidobacteria	57723|Acidobacteria	N	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,VCBS
DTH2_k127_9267023_0	860228.Ccan_09190	4.667e-182	583.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia,1EQQ9@1016|Capnocytophaga	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_9267023_1	755732.Fluta_2761	7.996e-155	495.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1HX15@117743|Flavobacteriia,2PAKR@246874|Cryomorphaceae	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DTH2_k127_9267023_13	1121011.AUCB01000005_gene2468	2.974e-47	174.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia,23HD2@178469|Arenibacter	976|Bacteroidetes	F	Cytidine and deoxycytidylate deaminase zinc-binding region	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
DTH2_k127_9267023_4	153721.MYP_2132	3.82e-90	323.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_9267023_5	153721.MYP_2132	1.971e-88	316.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_9267023_6	504487.JCM19302_2132	4.668e-77	265.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia	976|Bacteroidetes	E	Shikimate	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
DTH2_k127_9267023_3	1341155.FSS13T_21560	1.256e-94	322.0	COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DTH2_k127_9267023_8	391603.FBALC1_03307	2.155e-62	238.0	29X8I@1|root,30IXV@2|Bacteria,4P0MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9267023_7	391603.FBALC1_03307	2.323e-70	260.0	29X8I@1|root,30IXV@2|Bacteria,4P0MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9267023_11	679937.Bcop_2162	3.441e-49	189.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,4PKVA@976|Bacteroidetes,2G04V@200643|Bacteroidia,4AWE9@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_9267023_15	536227.CcarbDRAFT_0936	9.742e-11	72.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,36DR2@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_9267023_10	313606.M23134_00102	1.143e-51	192.0	COG3000@1|root,COG3000@2|Bacteria,4NMKR@976|Bacteroidetes,47P2V@768503|Cytophagia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DTH2_k127_9282681_25	1121859.KB890739_gene2561	1.42e-19	96.0	COG2067@1|root,COG2067@2|Bacteria,4NN8Q@976|Bacteroidetes,47PNT@768503|Cytophagia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
DTH2_k127_9282681_10	1565314.OA34_03790	3.8e-89	296.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2YN8W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Molybdenum cofactor biosynthesis protein	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
DTH2_k127_9282681_24	616991.JPOO01000003_gene1690	2.411e-21	100.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_9282681_7	1124780.ANNU01000013_gene3830	1.248e-107	356.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,47M7C@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
DTH2_k127_9282681_18	886377.Murru_3380	6.897e-41	155.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
DTH2_k127_9282681_12	491205.JARQ01000002_gene84	1.889e-79	278.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia,3ZR6U@59732|Chryseobacterium	976|Bacteroidetes	H	ThiF family	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
DTH2_k127_9282681_27	929713.NIASO_16470	6.168e-07	54.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DTH2_k127_9282681_19	1144313.PMI10_02131	2.534e-38	151.0	COG0746@1|root,COG0746@2|Bacteria,4NQQT@976|Bacteroidetes,1IIZW@117743|Flavobacteriia,2NUCX@237|Flavobacterium	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DTH2_k127_9282681_21	96561.Dole_0207	5.107e-28	116.0	COG2005@1|root,COG2005@2|Bacteria,1P9SX@1224|Proteobacteria,42VIX@68525|delta/epsilon subdivisions,2WS6N@28221|Deltaproteobacteria,2MNVD@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
DTH2_k127_9282681_9	1233951.IO90_09895	2.012e-92	317.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia,3HI4R@358033|Chryseobacterium	976|Bacteroidetes	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DTH2_k127_9282681_17	485918.Cpin_0678	1.746e-53	197.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_9282681_15	616991.JPOO01000003_gene1702	1.799e-61	222.0	COG2010@1|root,COG2010@2|Bacteria,4P8QV@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_9282681_0	616991.JPOO01000003_gene1701	0.0	2149.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
DTH2_k127_9282681_2	616991.JPOO01000003_gene1700	5.831e-293	902.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
DTH2_k127_9282681_16	616991.JPOO01000003_gene1699	3.839e-61	218.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
DTH2_k127_9282681_6	616991.JPOO01000003_gene1698	1.142e-107	353.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	narI	GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204	1.7.5.1	ko:K00370,ko:K00374,ko:K02575	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00615,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.8,5.A.3.1	-	iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897	Nitrate_red_gam
DTH2_k127_9282681_22	1229276.DI53_0974	4.361e-25	113.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1IPBV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
DTH2_k127_9282681_23	313603.FB2170_13011	8.952e-23	98.0	2E63Z@1|root,330SZ@2|Bacteria,4NVTW@976|Bacteroidetes,1I540@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9282681_8	694431.DESACE_03590	3.778e-97	326.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
DTH2_k127_9282681_14	1250232.JQNJ01000001_gene1913	6.084e-66	243.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH2_k127_9282681_1	1121904.ARBP01000002_gene7294	0.0	1215.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47NQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_9282681_11	1349822.NSB1T_00610	6.746e-81	276.0	COG0731@1|root,COG0731@2|Bacteria,4NJEM@976|Bacteroidetes,2FMWY@200643|Bacteroidia,22WAC@171551|Porphyromonadaceae	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_9282681_5	1358423.N180_04710	4.851e-115	383.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IWYK@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DTH2_k127_9282681_26	1469557.JSWF01000024_gene1840	5.704e-14	80.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1HY4W@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_9282681_4	296591.Bpro_3273	4.844e-196	627.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,4AAPE@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Major facilitator superfamily	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
DTH2_k127_9282681_28	797210.Halxa_3985	0.0002973	53.0	COG0589@1|root,arCOG03050@2157|Archaea,2Y0AV@28890|Euryarchaeota,23XU6@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_9282681_3	991.IW20_09835	1.216e-246	770.0	COG2223@1|root,COG2223@2|Bacteria,4NJ57@976|Bacteroidetes,1HWYX@117743|Flavobacteriia,2NV1N@237|Flavobacterium	976|Bacteroidetes	P	Transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,MgtE_N
DTH2_k127_9282681_13	1121012.AUKX01000020_gene1873	1.053e-69	252.0	COG3203@1|root,COG3203@2|Bacteria,4NDYW@976|Bacteroidetes,1HWYP@117743|Flavobacteriia,23GSE@178469|Arenibacter	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
DTH2_k127_9292290_25	153721.MYP_4063	1.923e-16	95.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_9292290_27	929556.Solca_3499	2.435e-10	75.0	COG3209@1|root,COG3405@1|root,COG4719@1|root,COG5184@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3405@2|Bacteria,COG4719@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PNF3@976|Bacteroidetes,1ISAX@117747|Sphingobacteriia	976|Bacteroidetes	GN	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9292290_6	1349785.BAUG01000016_gene1234	1.644e-138	443.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1HXEE@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
DTH2_k127_9292290_26	1408433.JHXV01000010_gene507	8.11e-14	78.0	2A3J1@1|root,30S22@2|Bacteria,4PCED@976|Bacteroidetes,1ICTW@117743|Flavobacteriia,2PC5J@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9292290_15	1408433.JHXV01000010_gene508	2.924e-49	187.0	29N3N@1|root,33PNI@2|Bacteria,4P1TW@976|Bacteroidetes,1IMS9@117743|Flavobacteriia,2PBW3@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9292290_1	1538644.KO02_03645	1.367e-209	656.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DTH2_k127_9292290_28	1121904.ARBP01000010_gene2360	3.762e-10	70.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	yttA	-	2.7.13.3	ko:K07184,ko:K07777,ko:K12065,ko:K13527	ko02020,ko03050,map02020,map03050	M00342,M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02044,ko03051	3.A.7.11.1	-	-	DUF3102,DUF3450
DTH2_k127_9292290_14	1218108.KB908302_gene2748	1.855e-61	215.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1I20A@117743|Flavobacteriia	976|Bacteroidetes	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DTH2_k127_9292290_21	1237149.C900_05112	9.188e-32	129.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia	976|Bacteroidetes	S	PFAM Membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DTH2_k127_9292290_0	925409.KI911562_gene1166	8.049e-258	818.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1IPUD@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_9292290_24	485918.Cpin_1739	6.936e-17	93.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes	976|Bacteroidetes	H	Gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_9292290_13	485918.Cpin_0389	1.7e-65	229.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DTH2_k127_9292290_5	269798.CHU_1289	1.24e-154	491.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DTH2_k127_9292290_12	755732.Fluta_0748	2.709e-74	280.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_9292290_7	1267211.KI669560_gene1038	6.47e-116	385.0	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,1IQ14@117747|Sphingobacteriia	976|Bacteroidetes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH2_k127_9292290_11	688270.Celal_2543	7.996e-78	270.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia,1F7RV@104264|Cellulophaga	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_9292290_3	641526.ADIWIN_2587	3.874e-171	571.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
DTH2_k127_9292290_23	1237149.C900_04718	2.872e-18	100.0	COG2353@1|root,COG2353@2|Bacteria,4PP17@976|Bacteroidetes,47YSH@768503|Cytophagia	976|Bacteroidetes	G	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9292290_9	1408433.JHXV01000018_gene3826	1.018e-86	318.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I2PT@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
DTH2_k127_9292290_18	1121373.KB903624_gene2463	2.48e-42	158.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DTH2_k127_9292290_19	694427.Palpr_0326	2.667e-41	153.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,2FT22@200643|Bacteroidia,22Y4P@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DTH2_k127_9292290_17	1168034.FH5T_18215	2.392e-45	168.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,2FSTU@200643|Bacteroidia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
DTH2_k127_9292290_16	1168289.AJKI01000002_gene2525	3.969e-47	186.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DTH2_k127_9292290_20	1121373.KB903620_gene2240	4.307e-34	143.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,47P6I@768503|Cytophagia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_9292290_2	509635.N824_06360	1.434e-204	646.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
DTH2_k127_9292290_10	485918.Cpin_2931	1.088e-78	273.0	COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,1IXEE@117747|Sphingobacteriia	976|Bacteroidetes	E	GSCFA family	-	-	-	-	-	-	-	-	-	-	-	-	GSCFA
DTH2_k127_9292290_8	1086011.HJ01_00090	3.148e-91	304.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1HWZD@117743|Flavobacteriia,2NTXS@237|Flavobacterium	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DTH2_k127_9292290_4	761193.Runsl_5035	6.297e-168	536.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M80@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
DTH2_k127_9292290_22	755732.Fluta_2092	2.757e-31	136.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
DTH2_k127_9321061_2	1166018.FAES_4389	3.162e-11	74.0	COG1577@1|root,COG3391@1|root,COG1577@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	mvaK2	-	2.7.1.36,2.7.1.43,2.7.4.2	ko:K00869,ko:K00938,ko:K16190	ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146	M00014,M00095	R01476,R02245,R03245	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH2_k127_9321061_1	1338011.BD94_1042	1.199e-56	213.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1I0XW@117743|Flavobacteriia,34PRA@308865|Elizabethkingia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
DTH2_k127_9321061_0	1313421.JHBV01000030_gene2179	5.413e-74	262.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
DTH2_k127_9394940_5	1341155.FSS13T_24480	1.211e-42	161.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia,2NTF8@237|Flavobacterium	976|Bacteroidetes	S	DinB superfamily	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DTH2_k127_9394940_0	755732.Fluta_2594	4.188e-155	499.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia,2PAIE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_9394940_2	929556.Solca_4283	1.956e-136	439.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1IQ02@117747|Sphingobacteriia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
DTH2_k127_9394940_1	880071.Fleli_1811	4.569e-148	475.0	COG3243@1|root,COG3243@2|Bacteria,4P0GQ@976|Bacteroidetes,47TSY@768503|Cytophagia	976|Bacteroidetes	I	PHB de-polymerase C-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
DTH2_k127_9394940_7	760192.Halhy_5351	3.839e-23	115.0	COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9394940_6	880071.Fleli_1812	2.059e-32	142.0	2AFJ1@1|root,315JT@2|Bacteria,4P311@976|Bacteroidetes,47V6D@768503|Cytophagia	976|Bacteroidetes	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
DTH2_k127_9394940_4	153721.MYP_2257	1.398e-46	171.0	COG2030@1|root,COG2030@2|Bacteria,4NPYH@976|Bacteroidetes,47PSF@768503|Cytophagia	976|Bacteroidetes	I	MaoC domain protein dehydratase	maoC	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
DTH2_k127_9394940_3	313606.M23134_00128	4.647e-102	337.0	COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,47N2B@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	fabG3	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_94217_12	1313421.JHBV01000028_gene1857	7.857e-23	108.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
DTH2_k127_94217_5	1121097.JCM15093_1557	8.691e-74	256.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,2FN1A@200643|Bacteroidia,4AK6Q@815|Bacteroidaceae	976|Bacteroidetes	H	Psort location Cytoplasmic, score 8.96	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH2_k127_94217_1	929556.Solca_1338	1.987e-170	540.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
DTH2_k127_94217_10	1380384.JADN01000004_gene2142	2.206e-33	136.0	COG3210@1|root,COG3210@2|Bacteria,4NW7P@976|Bacteroidetes,1I6RF@117743|Flavobacteriia	976|Bacteroidetes	MU	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_94217_9	1279009.ADICEAN_03093	6.238e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
DTH2_k127_94217_15	927658.AJUM01000034_gene259	1.919e-09	63.0	2CICV@1|root,33IPP@2|Bacteria,4NXPC@976|Bacteroidetes,2FZJR@200643|Bacteroidia,3XKCG@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_94217_11	929556.Solca_3135	1.047e-28	117.0	COG3411@1|root,COG3411@2|Bacteria,4NT2H@976|Bacteroidetes,1IT6E@117747|Sphingobacteriia	976|Bacteroidetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_94217_7	926549.KI421517_gene831	1.77e-52	204.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,47K28@768503|Cytophagia	976|Bacteroidetes	I	PFAM Outer membrane protein transport protein (OMPP1 FadL TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
DTH2_k127_94217_0	1168034.FH5T_15205	6.019e-261	810.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,2FMZT@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DTH2_k127_94217_6	742725.HMPREF9450_01118	2.292e-56	204.0	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,2FXHA@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_94217_4	1121898.Q766_00895	1.677e-116	382.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia,2NS6V@237|Flavobacterium	976|Bacteroidetes	I	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_94217_2	1168034.FH5T_06740	8.308e-127	417.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,2FPWJ@200643|Bacteroidia	976|Bacteroidetes	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_94217_3	1168034.FH5T_06745	8.189e-120	400.0	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,2G3BA@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_94217_8	926562.Oweho_1845	2.573e-52	197.0	COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1I785@117743|Flavobacteriia,2PAYX@246874|Cryomorphaceae	976|Bacteroidetes	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
DTH2_k127_94217_14	1408473.JHXO01000010_gene3715	5.706e-10	65.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9619327_7	929556.Solca_0930	3.043e-16	85.0	2DVQJ@1|root,32UZZ@2|Bacteria,4PGTB@976|Bacteroidetes,1IUA6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9619327_1	1094466.KQS_09265	2.389e-144	463.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1HXT8@117743|Flavobacteriia,2NSQS@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_9619327_3	860228.Ccan_05730	1.029e-114	372.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1HXUY@117743|Flavobacteriia,1ER5Q@1016|Capnocytophaga	976|Bacteroidetes	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DTH2_k127_9619327_5	471854.Dfer_5793	1.728e-61	220.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_9619327_4	153721.MYP_3970	5.76e-63	219.0	2FDT1@1|root,345TR@2|Bacteria,4P5ST@976|Bacteroidetes,47W7J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9619327_2	1349785.BAUG01000013_gene1028	1.544e-142	464.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HZ6Y@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DTH2_k127_9619327_8	926562.Oweho_2970	1.316e-15	78.0	2DFUX@1|root,2ZT8Y@2|Bacteria,4P92B@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9619327_9	694427.Palpr_2634	9.057e-12	67.0	COG3237@1|root,COG3237@2|Bacteria,4NUMZ@976|Bacteroidetes,2FW1I@200643|Bacteroidia,2317R@171551|Porphyromonadaceae	976|Bacteroidetes	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
DTH2_k127_9619327_0	1121373.KB903646_gene3347	8.806e-206	645.0	COG3007@1|root,COG3007@2|Bacteria,4NFV8@976|Bacteroidetes,47NF8@768503|Cytophagia	976|Bacteroidetes	I	Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)	fabV	-	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
DTH2_k127_9619327_6	1121875.KB907546_gene2466	1.001e-34	139.0	COG1670@1|root,COG1670@2|Bacteria,4NNE4@976|Bacteroidetes,1I1AJ@117743|Flavobacteriia	976|Bacteroidetes	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_9619327_10	1408433.JHXV01000017_gene1559	1.236e-05	56.0	COG1361@1|root,COG4886@1|root,COG1361@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	inlA	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF285,LRR_4,Lectin_legB,Strep_his_triad
DTH2_k127_9682745_0	1453500.AT05_00420	4.592e-139	462.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9682745_1	575590.HMPREF0156_00821	9.265e-13	79.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
DTH2_k127_9682745_2	1341155.FSS13T_21570	2.194e-09	59.0	COG3000@1|root,COG3000@2|Bacteria,4NMKR@976|Bacteroidetes,1IJ09@117743|Flavobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DTH2_k127_972928_12	929562.Emtol_3713	1.642e-63	224.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,47P9D@768503|Cytophagia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
DTH2_k127_972928_3	926549.KI421517_gene1683	6.157e-127	413.0	COG1363@1|root,COG1363@2|Bacteria,4NH34@976|Bacteroidetes,47MR1@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH2_k127_972928_15	1408433.JHXV01000001_gene721	3.946e-39	159.0	COG0457@1|root,COG0457@2|Bacteria,4PJHB@976|Bacteroidetes,1IMQ8@117743|Flavobacteriia,2PB7I@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_972928_2	1408433.JHXV01000005_gene2527	1.333e-134	432.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia,2PAIT@246874|Cryomorphaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
DTH2_k127_972928_14	1168034.FH5T_02835	3.263e-41	155.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,2FUDQ@200643|Bacteroidia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_972928_1	1406840.Q763_09925	2.564e-171	548.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1HX3N@117743|Flavobacteriia,2NSH7@237|Flavobacterium	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
DTH2_k127_972928_9	1408473.JHXO01000009_gene3354	1.141e-71	253.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,2FPK9@200643|Bacteroidia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_972928_10	1121897.AUGO01000003_gene1763	1.351e-70	243.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia,2NTPF@237|Flavobacterium	976|Bacteroidetes	J	Methyltransferase	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
DTH2_k127_972928_5	504472.Slin_1740	1.198e-96	331.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia	976|Bacteroidetes	CP	COGs COG1668 ABC-type Na efflux pump permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_972928_4	1168034.FH5T_05190	4.059e-114	376.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,2FMK3@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DTH2_k127_972928_6	1408433.JHXV01000006_gene2720	3.44e-91	321.0	COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,1IKD1@117743|Flavobacteriia,2PAST@246874|Cryomorphaceae	976|Bacteroidetes	A	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
DTH2_k127_972928_8	880071.Fleli_1299	8.858e-73	259.0	COG1835@1|root,COG1835@2|Bacteria,4NFYX@976|Bacteroidetes,47MCE@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_972928_0	1168034.FH5T_15140	3.135e-177	571.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia	976|Bacteroidetes	M	Psort location CytoplasmicMembrane, score 10.00	algI	-	-	-	-	-	-	-	-	-	-	-	MBOAT
DTH2_k127_972928_11	1519464.HY22_07700	8.657e-69	249.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	Z012_00180	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
DTH2_k127_972928_7	1168034.FH5T_15130	5.513e-86	302.0	COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,2G37X@200643|Bacteroidia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
DTH2_k127_972928_16	376686.Fjoh_1892	2.241e-31	126.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,1I2UP@117743|Flavobacteriia,2NWAC@237|Flavobacterium	976|Bacteroidetes	K	Transcriptional regulator	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
DTH2_k127_972928_13	313606.M23134_04297	2.566e-46	177.0	28J0S@1|root,2Z8XX@2|Bacteria,4P2J4@976|Bacteroidetes,47X8E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9801615_16	926562.Oweho_1054	2.163e-49	190.0	COG0438@1|root,COG0438@2|Bacteria,4PI54@976|Bacteroidetes,1I2FR@117743|Flavobacteriia,2PB22@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_9801615_22	1408433.JHXV01000010_gene535	3.313e-27	118.0	2AAU0@1|root,30Y70@2|Bacteria,4PBYC@976|Bacteroidetes,1ICQX@117743|Flavobacteriia,2PBTU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9801615_9	755732.Fluta_1042	2.432e-102	335.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia,2PA5G@246874|Cryomorphaceae	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
DTH2_k127_9801615_11	313603.FB2170_07769	2.411e-76	267.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1HX0P@117743|Flavobacteriia,2PGV3@252356|Maribacter	976|Bacteroidetes	M	Male sterility protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
DTH2_k127_9801615_21	1123008.KB905695_gene2740	4.312e-28	121.0	COG0671@1|root,COG0671@2|Bacteria,4NPUG@976|Bacteroidetes,2FSUS@200643|Bacteroidia,22YR5@171551|Porphyromonadaceae	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DTH2_k127_9801615_3	929556.Solca_0272	3.734e-135	437.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
DTH2_k127_9801615_13	873517.HMPREF1977_1959	7.826e-73	252.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia,1EQFC@1016|Capnocytophaga	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
DTH2_k127_9801615_2	1041826.FCOL_03420	9.656e-181	571.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia,2NSWV@237|Flavobacterium	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DTH2_k127_9801615_8	755732.Fluta_1156	1.192e-103	344.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia,2PABW@246874|Cryomorphaceae	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DTH2_k127_9801615_1	485917.Phep_0396	3.792e-288	890.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DTH2_k127_9801615_19	643867.Ftrac_2570	1.524e-42	162.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DTH2_k127_9801615_17	926562.Oweho_2371	7.533e-48	177.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia,2PB2M@246874|Cryomorphaceae	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
DTH2_k127_9801615_23	1150600.ADIARSV_4225	1.526e-21	95.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1ITY0@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DTH2_k127_9801615_6	509635.N824_08730	1.234e-110	368.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DTH2_k127_9801615_7	1120951.AUBG01000010_gene1918	2.02e-109	367.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia	976|Bacteroidetes	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_9801615_10	1121007.AUML01000019_gene772	7.162e-85	287.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia,2YHD2@290174|Aquimarina	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_9801615_20	679935.Alfi_1544	2.08e-29	122.0	COG4706@1|root,COG4706@2|Bacteria,4NSB5@976|Bacteroidetes,2FUX6@200643|Bacteroidia	976|Bacteroidetes	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9801615_4	269798.CHU_0390	1.062e-134	438.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,47KWN@768503|Cytophagia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
DTH2_k127_9801615_15	1121007.AUML01000019_gene778	3.458e-66	236.0	COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,1HWMC@117743|Flavobacteriia,2YGW7@290174|Aquimarina	976|Bacteroidetes	C	Dialkylrecorsinol condensing enzyme DarA	darA	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9801615_12	1297742.A176_03275	6.615e-74	250.0	COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria	1224|Proteobacteria	J	Translation initiation inhibitor, yjgF family	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_9801615_0	929556.Solca_3313	0.0	1437.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DTH2_k127_9801615_18	755732.Fluta_1722	4.098e-43	171.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia,2PAZZ@246874|Cryomorphaceae	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
DTH2_k127_9801615_14	1346330.M472_18335	1.089e-72	251.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1IQPW@117747|Sphingobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
DTH2_k127_9801615_5	945713.IALB_3004	5.034e-125	408.0	COG0276@1|root,COG0276@2|Bacteria	2|Bacteria	H	ferrochelatase activity	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
DTH2_k127_9801615_24	504472.Slin_6006	5.209e-08	63.0	COG2374@1|root,COG2374@2|Bacteria,4NRJZ@976|Bacteroidetes,47XAG@768503|Cytophagia	976|Bacteroidetes	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9843896_1	1341181.FLJC2902T_32330	1.124e-35	141.0	2CMH2@1|root,32SES@2|Bacteria,4NSUS@976|Bacteroidetes,1I479@117743|Flavobacteriia,2NUH7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9843896_0	700598.Niako_3251	5.214e-56	212.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_9843896_2	1185876.BN8_06365	1.954e-32	147.0	COG1044@1|root,COG5295@1|root,COG1044@2|Bacteria,COG5295@2|Bacteria,4NKG1@976|Bacteroidetes,47NK6@768503|Cytophagia	976|Bacteroidetes	MUW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH2_k127_9843896_3	755732.Fluta_1673	2.738e-29	136.0	COG2911@1|root,COG3266@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,4PKFD@976|Bacteroidetes,1IKC5@117743|Flavobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH2_k127_9843896_4	1313421.JHBV01000009_gene4138	9.634e-20	106.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes	976|Bacteroidetes	O	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9843896_7	216432.CA2559_04140	4.558e-07	64.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia	976|Bacteroidetes	L	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
DTH2_k127_9843896_6	746697.Aeqsu_1668	1.057e-12	81.0	COG2358@1|root,COG3291@1|root,COG2358@2|Bacteria,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,1I9DA@117743|Flavobacteriia	976|Bacteroidetes	S	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_9843896_8	1406840.Q763_00210	0.0001366	53.0	COG3291@1|root,COG3291@2|Bacteria,4PPWJ@976|Bacteroidetes,1IN64@117743|Flavobacteriia,2P0WR@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9843896_5	1121870.AUAA01000069_gene2596	5.897e-15	76.0	2CMH2@1|root,32SES@2|Bacteria,4NSUS@976|Bacteroidetes,1IM90@117743|Flavobacteriia,3HJ2N@358033|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9954260_7	1121889.AUDM01000007_gene930	1.322e-58	214.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.121	ko:K07004,ko:K20755	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Exo_endo_phos,LTD,Omp28,Peptidase_M14
DTH2_k127_9954260_0	1121889.AUDM01000003_gene2301	0.0	1234.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia,2NSWW@237|Flavobacterium	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
DTH2_k127_9954260_6	525373.HMPREF0766_12374	4.481e-60	219.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_9954260_4	32057.KB217483_gene9704	7.345e-82	286.0	COG0614@1|root,COG0614@2|Bacteria,1G37R@1117|Cyanobacteria,1HIY1@1161|Nostocales	1117|Cyanobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
DTH2_k127_9954260_5	1469557.JSWF01000025_gene1369	2.578e-71	252.0	COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,1HXH4@117743|Flavobacteriia	976|Bacteroidetes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
DTH2_k127_9954260_8	385682.AFSL01000044_gene350	1.402e-55	202.0	COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,2FMCI@200643|Bacteroidia,3XJ55@558415|Marinilabiliaceae	976|Bacteroidetes	HP	ATPases associated with a variety of cellular activities	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
DTH2_k127_9954260_9	700598.Niako_5254	2.883e-35	139.0	COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
DTH2_k127_9954260_1	755732.Fluta_0646	3.944e-207	651.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia,2PAK2@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_9954260_3	1408433.JHXV01000007_gene2890	1.052e-105	353.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia,2PBGA@246874|Cryomorphaceae	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
DTH2_k127_9954260_2	1237149.C900_03957	6.131e-114	374.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,47MQV@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DTH2_k127_9954260_10	983548.Krodi_2507	4.492e-35	138.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia,37F38@326319|Dokdonia	976|Bacteroidetes	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
## 2813 queries scanned
## Total time (seconds): 133.97209906578064
## Rate: 21.00 q/s