## Fri Nov 15 01:09:09 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin1/DTH_2_bin.48.fa -m mmseqs --itype genome -o DTH_2_bin.48 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/DTH_2_bin.48 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DTH2_k127_10010005_5	1355374.JARU01000006_gene1776	1.242e-73	253.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2YP1G@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH2	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_10010005_6	1168034.FH5T_08380	6.934e-73	250.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,2FP46@200643|Bacteroidia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DTH2_k127_10010005_0	926549.KI421517_gene2701	0.0	1087.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,47M8U@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DTH2_k127_10010005_8	1227739.Hsw_2857	2.004e-48	183.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia	976|Bacteroidetes	S	PFAM PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
DTH2_k127_10010005_7	926562.Oweho_1744	1.581e-68	256.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,1I8D6@117743|Flavobacteriia,2PARN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10010005_1	521097.Coch_0553	2.304e-145	469.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia,1EQMD@1016|Capnocytophaga	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_10010005_2	1004149.AFOE01000007_gene1219	2.743e-129	421.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_10010005_3	700598.Niako_5173	5.568e-126	411.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1IZDH@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_10010005_4	929703.KE386491_gene3346	4.236e-83	281.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DTH2_k127_1001455_2	153721.MYP_79	2.357e-73	253.0	COG0072@1|root,COG0072@2|Bacteria,4NF5B@976|Bacteroidetes,47JAK@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DTH2_k127_1001455_0	411476.BACOVA_00997	2.079e-127	428.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,2FM62@200643|Bacteroidia,4AKJC@815|Bacteroidaceae	976|Bacteroidetes	L	DNA mismatch repair protein MutS	mutS_2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
DTH2_k127_1001455_4	760192.Halhy_3285	5.689e-22	112.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
DTH2_k127_1001455_1	926549.KI421517_gene3311	8.761e-74	276.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_1001455_3	1538644.KO02_04395	5.108e-43	160.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1IPB3@117747|Sphingobacteriia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
DTH2_k127_10020634_2	1095769.CAHF01000011_gene2304	1.831e-45	168.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VRG7@28216|Betaproteobacteria,477HE@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
DTH2_k127_10020634_1	1237149.C900_00815	1.811e-46	179.0	COG1196@1|root,COG1196@2|Bacteria,4PMEM@976|Bacteroidetes,47Y37@768503|Cytophagia	976|Bacteroidetes	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
DTH2_k127_10020634_0	1121904.ARBP01000003_gene6201	1.754e-96	332.0	COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_10020634_3	1124780.ANNU01000023_gene3153	1.538e-16	80.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,47JJU@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_10037374_2	880071.Fleli_3259	8.605e-58	210.0	COG4249@1|root,COG4249@2|Bacteria,4NS33@976|Bacteroidetes,47SWU@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
DTH2_k127_10037374_3	1144313.PMI10_01738	1.32e-05	58.0	COG1357@1|root,COG1357@2|Bacteria,4PNZS@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_10037374_0	755732.Fluta_1284	1.227e-129	446.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_10037374_1	1408433.JHXV01000027_gene3728	1.212e-105	350.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_10040506_14	1408813.AYMG01000023_gene2121	7.385e-34	132.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1ISXS@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DTH2_k127_10040506_9	1408813.AYMG01000023_gene2122	6.207e-62	214.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DTH2_k127_10040506_13	755732.Fluta_0770	7.748e-39	145.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1I2TE@117743|Flavobacteriia,2PAYV@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DTH2_k127_10040506_17	1121097.JCM15093_3355	3.233e-11	65.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,2FUJB@200643|Bacteroidia,4ARW0@815|Bacteroidaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DTH2_k127_10040506_7	929556.Solca_3020	2.671e-70	239.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1IRSN@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DTH2_k127_10040506_3	1538644.KO02_02360	4.241e-114	372.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1IPKE@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DTH2_k127_10040506_11	1168034.FH5T_12840	2.091e-44	165.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,2FS3J@200643|Bacteroidia	976|Bacteroidetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DTH2_k127_10040506_12	1408473.JHXO01000006_gene1286	2.754e-42	156.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,2FT46@200643|Bacteroidia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DTH2_k127_10040506_2	926562.Oweho_3062	3.464e-135	434.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,1HXDV@117743|Flavobacteriia,2PAH2@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DTH2_k127_10040506_15	886379.AEWI01000002_gene516	2.032e-31	125.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,3XKBV@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein L23	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DTH2_k127_10040506_5	742726.HMPREF9448_02477	1.455e-78	268.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,2FM1W@200643|Bacteroidia,22VXN@171551|Porphyromonadaceae	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DTH2_k127_10040506_4	468059.AUHA01000002_gene1308	8.07e-107	348.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DTH2_k127_10040506_10	1346330.M472_19005	2.033e-52	186.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1ISQN@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DTH2_k127_10040506_0	929556.Solca_3034	0.0	1169.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_10040506_6	714943.Mucpa_2116	1.013e-70	241.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1IRJ7@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DTH2_k127_10040506_8	929556.Solca_3036	1.166e-67	231.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1IS0J@117747|Sphingobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DTH2_k127_10040506_16	1123248.KB893385_gene4872	4.244e-26	128.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_10040506_1	153721.MYP_3099	4.27e-219	761.0	COG2152@1|root,COG3291@1|root,COG2152@2|Bacteria,COG3291@2|Bacteria,4PHTS@976|Bacteroidetes,47Q40@768503|Cytophagia	976|Bacteroidetes	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_10047472_0	755732.Fluta_3340	1.856e-108	386.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IKE7@117743|Flavobacteriia,2PC6R@246874|Cryomorphaceae	2|Bacteria	G	SPTR Cell surface protein	-	-	3.2.1.18	ko:K01186,ko:K14274	ko00040,ko00511,ko00600,ko04142,map00040,map00511,map00600,map04142	-	R02427,R04018	RC00028,RC00077,RC00713	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,He_PIG,NPCBM_assoc,PEGA,SGL
DTH2_k127_10047472_1	1469557.JSWF01000028_gene2971	7.062e-06	60.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1I06M@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
DTH2_k127_10062268_0	1408433.JHXV01000027_gene3728	0.0	1215.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_10074488_2	485917.Phep_1166	4.777e-155	501.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
DTH2_k127_10074488_1	927658.AJUM01000034_gene127	1.028e-180	580.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,2FQNC@200643|Bacteroidia,3XJTF@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_10074488_3	755732.Fluta_2549	3.04e-111	368.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_10074488_0	313606.M23134_00640	4.196e-191	632.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DTH2_k127_10080678_0	1122179.KB890435_gene931	2.754e-149	492.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH2_k127_10080678_8	1408433.JHXV01000015_gene1740	4.786e-16	83.0	2DGVM@1|root,2ZXFN@2|Bacteria,4P8FH@976|Bacteroidetes,1IMT9@117743|Flavobacteriia,2PC3X@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10080678_6	929703.KE386491_gene174	3.773e-23	106.0	COG3209@1|root,COG3209@2|Bacteria,4P5T8@976|Bacteroidetes,47W80@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10080678_5	929703.KE386491_gene175	4.998e-65	231.0	COG3025@1|root,COG3025@2|Bacteria,4NM6K@976|Bacteroidetes,47PAH@768503|Cytophagia	976|Bacteroidetes	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH2_k127_10080678_4	929703.KE386491_gene176	8.121e-66	230.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,47PEP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
DTH2_k127_10080678_3	742767.HMPREF9456_01364	5.907e-70	239.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,2FNVA@200643|Bacteroidia,22XNK@171551|Porphyromonadaceae	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
DTH2_k127_10080678_1	509635.N824_12965	5.607e-126	415.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1IPX7@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10080678_2	926562.Oweho_1768	7.769e-109	359.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,2PAHV@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DTH2_k127_10082321_4	755732.Fluta_1341	1.978e-32	145.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10082321_1	485918.Cpin_3480	1.32e-109	358.0	28I0D@1|root,2Z857@2|Bacteria,4NFD6@976|Bacteroidetes,1IRJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1826
DTH2_k127_10082321_0	1168034.FH5T_10725	9.971e-159	505.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,2FM7E@200643|Bacteroidia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH2_k127_10082321_3	1408433.JHXV01000010_gene584	4.71e-85	284.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia,2PBNV@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_10082321_2	1408433.JHXV01000010_gene583	3.278e-88	306.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	2.1.1.72,3.1.4.46,3.2.1.1	ko:K00571,ko:K01126,ko:K01176	ko00500,ko00564,ko01100,ko04973,map00500,map00564,map01100,map04973	-	R01030,R01470,R02108,R02112,R11262	RC00017,RC00425	ko00000,ko00001,ko01000,ko02048	-	GH13	-	CHU_C,PKD
DTH2_k127_10082321_5	1408433.JHXV01000004_gene3425	1.809e-15	79.0	COG1309@1|root,COG1309@2|Bacteria,4NTWF@976|Bacteroidetes,1I1HH@117743|Flavobacteriia,2PBTQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Bacterial transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
DTH2_k127_10082777_14	1501391.LG35_04105	0.0004605	44.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,2FUC5@200643|Bacteroidia,22UM1@171550|Rikenellaceae	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
DTH2_k127_10082777_4	1408433.JHXV01000028_gene2125	1.427e-80	290.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBC5@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_16,TPR_8
DTH2_k127_10082777_5	926562.Oweho_2671	2.687e-67	241.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia,2PAWA@246874|Cryomorphaceae	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
DTH2_k127_10082777_1	153721.MYP_1661	1.137e-173	562.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,47NYD@768503|Cytophagia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_10082777_3	714943.Mucpa_3181	3.593e-122	396.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1INQC@117747|Sphingobacteriia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DTH2_k127_10082777_0	1408433.JHXV01000016_gene1828	1.775e-281	906.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia,2PA94@246874|Cryomorphaceae	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10082777_7	1200792.AKYF01000010_gene1705	4.759e-51	185.0	COG1670@1|root,COG1670@2|Bacteria,1V5WS@1239|Firmicutes,4HH37@91061|Bacilli,26Y03@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_10082777_11	755732.Fluta_3682	2.168e-38	154.0	COG4886@1|root,COG4886@2|Bacteria,4NPNU@976|Bacteroidetes,1I2Q2@117743|Flavobacteriia,2PBZ9@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Leucine Rich Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,Pkinase_Tyr
DTH2_k127_10082777_9	1279009.ADICEAN_00647	3.249e-40	164.0	COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,47QA7@768503|Cytophagia	976|Bacteroidetes	S	Glucose-regulated metallo-peptidase M90	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
DTH2_k127_10082777_2	714943.Mucpa_6437	2.212e-122	400.0	COG3129@1|root,COG3129@2|Bacteria,4NF3Z@976|Bacteroidetes,1INNZ@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
DTH2_k127_10082777_10	468059.AUHA01000003_gene1556	5.113e-39	154.0	COG1416@1|root,COG1416@2|Bacteria,4NH85@976|Bacteroidetes,1IX7M@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10082777_6	1304885.AUEY01000090_gene2886	4.903e-57	203.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MJPY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
DTH2_k127_10082777_13	1189619.pgond44_11081	1.96e-25	110.0	2DNNF@1|root,32Y92@2|Bacteria,4PMHZ@976|Bacteroidetes,1IKMZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10082777_8	945713.IALB_1953	1.426e-50	187.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_10083901_2	1341155.FSS13T_26600	1.189e-67	235.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
DTH2_k127_10083901_1	313606.M23134_03474	1.611e-108	376.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,47TYP@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
DTH2_k127_10083901_6	313606.M23134_04797	2.318e-21	98.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,47RHF@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_10083901_3	880070.Cycma_0374	1.665e-44	164.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,47VEQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
DTH2_k127_10083901_4	1267211.KI669560_gene838	1.404e-31	128.0	2BFVS@1|root,329R5@2|Bacteria,4NSXJ@976|Bacteroidetes,1ITXH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10083901_0	1484460.JSWG01000008_gene1892	7.757e-142	469.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH2_k127_10083901_5	755732.Fluta_3847	4.369e-27	112.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
DTH2_k127_10086966_4	1450525.JATV01000011_gene1424	9.807e-91	305.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1HX5W@117743|Flavobacteriia,2NSQI@237|Flavobacterium	976|Bacteroidetes	H	Uroporphyrin-III C-methyltransferase	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
DTH2_k127_10086966_2	926549.KI421517_gene819	6.942e-155	504.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,47YJA@768503|Cytophagia	976|Bacteroidetes	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
DTH2_k127_10086966_5	1122604.JONR01000029_gene3385	9.291e-74	254.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,1X4PS@135614|Xanthomonadales	135614|Xanthomonadales	EH	Belongs to the PAPS reductase family. CysH subfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
DTH2_k127_10086966_3	929556.Solca_2248	9.665e-117	388.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
DTH2_k127_10086966_1	1313421.JHBV01000015_gene5798	5.694e-178	586.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IR64@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
DTH2_k127_10086966_6	700598.Niako_4028	8.322e-44	171.0	COG0778@1|root,COG0778@2|Bacteria,4NPZV@976|Bacteroidetes	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DTH2_k127_10086966_7	616991.JPOO01000001_gene4483	0.0001375	53.0	2CBAQ@1|root,32U2I@2|Bacteria,4NTIM@976|Bacteroidetes,1I3ZJ@117743|Flavobacteriia,23HJ6@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10086966_0	1408433.JHXV01000027_gene3728	9.04e-189	624.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_1009476_3	468059.AUHA01000002_gene15	4.857e-57	209.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1ISN7@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
DTH2_k127_1009476_2	743722.Sph21_2249	4.633e-64	223.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1IS3F@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
DTH2_k127_1009476_0	1408433.JHXV01000007_gene2894	3.103e-195	614.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2PAJV@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_1009476_6	762968.HMPREF9441_03900	8.308e-17	82.0	COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
DTH2_k127_1009476_1	929556.Solca_0409	1.768e-98	329.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1IP2Y@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH2_k127_1009476_5	468059.AUHA01000002_gene10	3.695e-29	119.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1ITNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
DTH2_k127_1009476_4	153721.MYP_4660	3.621e-47	178.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_1009476_7	1300143.CCAV010000005_gene3788	2.814e-13	71.0	2ABX1@1|root,311E6@2|Bacteria,4PG7F@976|Bacteroidetes,1IH30@117743|Flavobacteriia,3ZSX4@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1029513_8	869213.JCM21142_279	2.447e-83	285.0	COG0642@1|root,COG2208@1|root,COG3292@1|root,COG2205@2|Bacteria,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes	976|Bacteroidetes	KT	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_1029513_2	153721.MYP_3699	6.187e-182	576.0	COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,47XY7@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.49	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01287,R01288,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH2_k127_1029513_12	485918.Cpin_3731	2.203e-48	177.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,1IT1R@117747|Sphingobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
DTH2_k127_1029513_6	700598.Niako_6988	4.217e-139	449.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
DTH2_k127_1029513_9	714943.Mucpa_3515	1.141e-77	271.0	COG1511@1|root,COG1511@2|Bacteria,4PMPJ@976|Bacteroidetes,1IQJY@117747|Sphingobacteriia	976|Bacteroidetes	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1029513_3	929556.Solca_3842	8.18e-174	574.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
DTH2_k127_1029513_14	1408433.JHXV01000015_gene1725	3.667e-38	147.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,1ICR4@117743|Flavobacteriia,2PBUN@246874|Cryomorphaceae	976|Bacteroidetes	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
DTH2_k127_1029513_15	755732.Fluta_1169	4.645e-32	128.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia,2PB6N@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1029513_10	1121097.JCM15093_2962	1.904e-68	242.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,4ANA5@815|Bacteroidaceae	976|Bacteroidetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH2_k127_1029513_5	869213.JCM21142_41583	3.954e-151	484.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DTH2_k127_1029513_18	1123037.AUDE01000032_gene2254	2.641e-18	88.0	COG3071@1|root,COG3071@2|Bacteria,4NUU1@976|Bacteroidetes	976|Bacteroidetes	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17,TPR_8
DTH2_k127_1029513_1	926549.KI421517_gene278	8.905e-235	756.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,47KJ1@768503|Cytophagia	976|Bacteroidetes	CE	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
DTH2_k127_1029513_11	1237149.C900_01020	2.766e-51	186.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia	976|Bacteroidetes	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
DTH2_k127_1029513_7	1450525.JATV01000006_gene961	1.043e-96	322.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia,2NTCR@237|Flavobacterium	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH2_k127_1029513_17	755732.Fluta_1328	4.765e-26	126.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4PM49@976|Bacteroidetes,1IJJ0@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_4
DTH2_k127_1029513_19	1121396.KB893110_gene1903	0.000478	53.0	COG2885@1|root,COG3291@1|root,COG3866@1|root,COG5386@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,COG3866@2|Bacteria,COG5386@2|Bacteria,1PHGF@1224|Proteobacteria,4378N@68525|delta/epsilon subdivisions,2X9WI@28221|Deltaproteobacteria,2MN4C@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_1029513_13	1121957.ATVL01000014_gene1459	3.445e-44	184.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1029513_16	1122176.KB903531_gene2840	3.28e-28	132.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
DTH2_k127_1029513_4	269798.CHU_0279	1.114e-155	496.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,47KA2@768503|Cytophagia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH2_k127_1029513_0	1094466.KQS_05315	2.323e-295	919.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1HX75@117743|Flavobacteriia,2NTDV@237|Flavobacterium	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
DTH2_k127_1057637_0	762903.Pedsa_2021	0.0	1045.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
DTH2_k127_1057637_1	485918.Cpin_0182	2.36e-97	324.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_1061130_4	1408433.JHXV01000014_gene3643	8.505e-187	594.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia,2PAH6@246874|Cryomorphaceae	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
DTH2_k127_1061130_21	1121904.ARBP01000016_gene5203	6.646e-39	147.0	COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,47V9S@768503|Cytophagia	976|Bacteroidetes	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
DTH2_k127_1061130_16	1111730.ATTM01000003_gene471	1.749e-73	258.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia,2NSYZ@237|Flavobacterium	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_1061130_14	1121912.AUHD01000006_gene1212	7.414e-85	291.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia	976|Bacteroidetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
DTH2_k127_1061130_17	1168034.FH5T_09875	1.916e-68	237.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,2FNWA@200643|Bacteroidia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
DTH2_k127_1061130_6	523791.Kkor_0379	1.189e-168	534.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,1RX6Z@1236|Gammaproteobacteria,1XRR2@135619|Oceanospirillales	135619|Oceanospirillales	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
DTH2_k127_1061130_20	1121904.ARBP01000007_gene2943	7.557e-44	179.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1061130_1	468059.AUHA01000006_gene2901	4.784e-292	907.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH2_k127_1061130_19	1453498.LG45_14635	1.356e-51	186.0	COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes,1I30R@117743|Flavobacteriia,2NZ02@237|Flavobacterium	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
DTH2_k127_1061130_11	1121889.AUDM01000010_gene593	1.604e-128	415.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia,2P02Z@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	-	-	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_1061130_8	1341155.FSS13T_00100	6.122e-138	443.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1HZY7@117743|Flavobacteriia,2NUSF@237|Flavobacterium	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
DTH2_k127_1061130_0	1341155.FSS13T_00110	0.0	1468.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1HXFG@117743|Flavobacteriia,2NV9I@237|Flavobacterium	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
DTH2_k127_1061130_15	1123037.AUDE01000032_gene2260	4.501e-78	263.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1I1A5@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
DTH2_k127_1061130_23	1191523.MROS_0340	1.876e-34	134.0	COG2151@1|root,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	paaD	-	-	ko:K02612,ko:K03593	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko03029,ko03036	-	-	-	FeS_assembly_P
DTH2_k127_1061130_18	1121889.AUDM01000028_gene485	2.147e-57	202.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia,2NVZC@237|Flavobacterium	976|Bacteroidetes	S	Fe-S metabolism protein SufE	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
DTH2_k127_1061130_5	926562.Oweho_2651	3.097e-173	552.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia,2PAEG@246874|Cryomorphaceae	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DTH2_k127_1061130_7	1454007.JAUG01000022_gene1229	7.686e-145	469.0	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,1IQ14@117747|Sphingobacteriia	976|Bacteroidetes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH2_k127_1061130_9	1123248.KB893315_gene3167	2.697e-135	439.0	COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,1INUS@117747|Sphingobacteriia	976|Bacteroidetes	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
DTH2_k127_1061130_13	468059.AUHA01000002_gene235	1.122e-99	335.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,1IRWP@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
DTH2_k127_1061130_2	391596.PBAL39_19195	1.371e-252	785.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IP39@117747|Sphingobacteriia	976|Bacteroidetes	E	COG3104 Dipeptide tripeptide permease	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_1061130_3	643867.Ftrac_3705	4.373e-198	623.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_1061130_12	1313301.AUGC01000015_gene1882	4.235e-101	339.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes	976|Bacteroidetes	S	Succinylglutamate desuccinylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
DTH2_k127_1061130_10	313606.M23134_02382	1.116e-129	420.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,47KJX@768503|Cytophagia	976|Bacteroidetes	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
DTH2_k127_1061130_22	1237149.C900_04900	5.881e-38	148.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
DTH2_k127_1061130_24	1408473.JHXO01000006_gene1235	8.17e-14	73.0	COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes	976|Bacteroidetes	E	fad dependent oxidoreductase	thiO	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH2_k127_106723_1	991.IW20_10800	1.916e-76	260.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia,2NUAF@237|Flavobacterium	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_106723_0	755732.Fluta_2685	6.216e-80	284.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_106723_2	391587.KAOT1_12627	8.444e-24	102.0	2AE9W@1|root,31442@2|Bacteria,4NQUB@976|Bacteroidetes,1IA11@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1073143_9	1127692.HMPREF9075_00406	6.247e-07	53.0	2D7E4@1|root,32TNW@2|Bacteria,4NSYH@976|Bacteroidetes,1I4B8@117743|Flavobacteriia,1EQ7E@1016|Capnocytophaga	976|Bacteroidetes	S	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476
DTH2_k127_1073143_8	1121930.AQXG01000003_gene2555	5.922e-12	70.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	arcB_2	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
DTH2_k127_1073143_5	1121104.AQXH01000001_gene1425	8.172e-43	174.0	COG3920@1|root,COG5002@1|root,COG3920@2|Bacteria,COG5002@2|Bacteria,4NINT@976|Bacteroidetes,1IT68@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_3,PAS_9
DTH2_k127_1073143_3	1380384.JADN01000003_gene479	1.731e-68	252.0	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
DTH2_k127_1073143_1	929562.Emtol_2583	2.661e-176	561.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_1073143_4	1048983.EL17_22130	8.308e-57	206.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,47XPZ@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
DTH2_k127_1073143_0	926549.KI421517_gene3358	0.0	1207.0	COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
DTH2_k127_1073143_2	1121875.KB907550_gene731	5.154e-155	497.0	COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DTH2_k127_1073143_7	761193.Runsl_2295	6.134e-21	96.0	COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,47RC7@768503|Cytophagia	976|Bacteroidetes	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
DTH2_k127_1073143_6	1313301.AUGC01000008_gene484	2.772e-29	128.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes	976|Bacteroidetes	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_1121848_0	714943.Mucpa_0044	6.293e-299	930.0	COG0155@1|root,COG1895@1|root,COG0155@2|Bacteria,COG1895@2|Bacteria,4NENW@976|Bacteroidetes,1INY4@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitrite and sulphite reductase 4Fe-4S	cysI	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr,TusA
DTH2_k127_1121848_27	755732.Fluta_1166	1.164e-31	132.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia,2PB7N@246874|Cryomorphaceae	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
DTH2_k127_1121848_13	1107311.Q767_11465	1.193e-104	347.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1HX6V@117743|Flavobacteriia,2NTZB@237|Flavobacterium	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DTH2_k127_1121848_2	1150600.ADIARSV_4222	9.749e-288	889.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DTH2_k127_1121848_22	926549.KI421517_gene2267	5.361e-44	167.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DTH2_k127_1121848_21	391587.KAOT1_17548	1.361e-47	177.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
DTH2_k127_1121848_31	1236504.HMPREF2132_10770	3.852e-18	86.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DTH2_k127_1121848_14	762903.Pedsa_2511	1.668e-103	349.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DTH2_k127_1121848_37	926549.KI421517_gene2271	0.0001238	49.0	2DS0X@1|root,33E0E@2|Bacteria,4NXPR@976|Bacteroidetes,47SUT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1121848_36	1279009.ADICEAN_03052	1.858e-09	61.0	2DQFZ@1|root,336KY@2|Bacteria,4NVIZ@976|Bacteroidetes,47SK8@768503|Cytophagia	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
DTH2_k127_1121848_25	886379.AEWI01000022_gene108	1.072e-35	140.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH2_k127_1121848_8	1168034.FH5T_08815	4.666e-142	487.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,2G3G6@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
DTH2_k127_1121848_17	926562.Oweho_2361	2.562e-73	256.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia,2PBQF@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_1121848_5	1185876.BN8_06139	2.367e-185	586.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
DTH2_k127_1121848_6	485918.Cpin_2050	2.147e-159	513.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1INRC@117747|Sphingobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
DTH2_k127_1121848_33	269798.CHU_2994	8.449e-14	81.0	COG1388@1|root,COG1388@2|Bacteria,4NPNH@976|Bacteroidetes,47Q7J@768503|Cytophagia	976|Bacteroidetes	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
DTH2_k127_1121848_1	1341181.FLJC2902T_12240	1.029e-288	891.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia,2NUBG@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH2_k127_1121848_12	929556.Solca_3490	7.172e-107	359.0	COG1225@1|root,COG1225@2|Bacteria,4NEEA@976|Bacteroidetes,1INVF@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_1121848_23	761193.Runsl_1795	3.586e-41	158.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
DTH2_k127_1121848_30	1250005.PHEL85_3207	7.202e-19	92.0	2E0HI@1|root,32W3C@2|Bacteria,4NQ7D@976|Bacteroidetes,1I349@117743|Flavobacteriia,3VXB8@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1121848_9	929556.Solca_2818	2.681e-136	438.0	COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,1IRFX@117747|Sphingobacteriia	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH2_k127_1121848_15	643867.Ftrac_1924	1.001e-89	323.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NJKM@976|Bacteroidetes,47NZZ@768503|Cytophagia	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_1121848_4	926556.Echvi_1296	1.171e-191	611.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH2_k127_1121848_26	755732.Fluta_1540	1.646e-35	138.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia,2PB44@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
DTH2_k127_1121848_28	153721.MYP_190	2.032e-30	129.0	2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1121848_20	1121904.ARBP01000009_gene4385	1.31e-47	185.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1121848_32	1267211.KI669560_gene1369	1.533e-17	99.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_1121848_11	313606.M23134_02237	1.845e-107	394.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_1121848_29	1313421.JHBV01000036_gene2474	4.772e-20	108.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_1121848_18	755732.Fluta_2398	2.619e-59	219.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_1121848_19	445961.IW15_17020	2.65e-50	181.0	2A94U@1|root,30Y94@2|Bacteria,4NP54@976|Bacteroidetes,1I2IQ@117743|Flavobacteriia,3ZS2M@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1121848_10	1124780.ANNU01000017_gene1935	1.164e-119	396.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47JNQ@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	nylB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_1121848_24	929556.Solca_1203	8.042e-41	154.0	2AGNU@1|root,316WB@2|Bacteria,4NSNZ@976|Bacteroidetes,1ISU7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1121848_16	1408433.JHXV01000006_gene2629	3.847e-88	296.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1HY85@117743|Flavobacteriia,2PATH@246874|Cryomorphaceae	976|Bacteroidetes	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
DTH2_k127_1121848_3	1121373.KB903622_gene2826	4.796e-271	845.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,47KUE@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DTH2_k127_1121848_7	153721.MYP_448	9.924e-154	496.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KDQ@768503|Cytophagia	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH2_k127_1130450_3	865937.Gilli_3085	6.346e-88	295.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,1HXFE@117743|Flavobacteriia,2P626@244698|Gillisia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DTH2_k127_1130450_2	391587.KAOT1_04817	6.885e-132	429.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH2_k127_1130450_4	1408433.JHXV01000036_gene268	5.339e-38	153.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes,1IAKI@117743|Flavobacteriia,2PB7R@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1130450_0	1168034.FH5T_12365	1.745e-166	535.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,2FMUQ@200643|Bacteroidia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
DTH2_k127_1130450_1	755732.Fluta_2801	3.63e-151	483.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1HWQX@117743|Flavobacteriia,2PA8X@246874|Cryomorphaceae	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DTH2_k127_1236960_1	1349822.NSB1T_00560	2.523e-156	499.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,2FNMT@200643|Bacteroidia,22WRX@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_1236960_3	1168034.FH5T_07975	6.585e-12	78.0	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes,2FVZZ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1236960_2	1168034.FH5T_07980	1.215e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_1236960_0	714943.Mucpa_0211	3.701e-248	771.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH2_k127_1237220_5	926549.KI421517_gene1833	2.889e-162	514.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_1237220_23	1121889.AUDM01000002_gene435	1.962e-22	104.0	COG4969@1|root,COG4969@2|Bacteria,4NVUE@976|Bacteroidetes,1I5FG@117743|Flavobacteriia,2NXA9@237|Flavobacterium	976|Bacteroidetes	NU	Belongs to the N-Me-Phe pilin family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1237220_1	1286632.P278_24770	2.637e-229	713.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
DTH2_k127_1237220_0	376686.Fjoh_0728	1.199e-234	727.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia,2NTEM@237|Flavobacterium	976|Bacteroidetes	Q	Homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
DTH2_k127_1237220_12	760192.Halhy_4832	2.74e-94	315.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1INMV@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH2_k127_1237220_6	938709.AUSH02000018_gene1104	6.192e-129	420.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes	976|Bacteroidetes	EJ	L-asparaginase, type I	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DTH2_k127_1237220_21	755732.Fluta_1991	1.405e-43	171.0	COG2273@1|root,COG2273@2|Bacteria,4NKMT@976|Bacteroidetes	976|Bacteroidetes	G	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16
DTH2_k127_1237220_20	700598.Niako_3294	2.974e-47	174.0	2DBIE@1|root,32TXH@2|Bacteria,4NSJE@976|Bacteroidetes,1ITSC@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1237220_18	631362.Thi970DRAFT_04553	2.594e-48	179.0	296YQ@1|root,2ZU7A@2|Bacteria,1RDAE@1224|Proteobacteria,1S6SJ@1236|Gammaproteobacteria,1X06C@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1237220_14	395495.Lcho_1136	5.239e-73	256.0	COG3005@1|root,COG3005@2|Bacteria,1QZ6I@1224|Proteobacteria,2VPS8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
DTH2_k127_1237220_17	1408473.JHXO01000001_gene2054	1.249e-52	198.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,2FT47@200643|Bacteroidia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DTH2_k127_1237220_3	929703.KE386491_gene401	1.959e-175	553.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
DTH2_k127_1237220_10	1408473.JHXO01000001_gene1964	6.374e-107	359.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
DTH2_k127_1237220_22	269798.CHU_3629	1.144e-32	129.0	COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia	976|Bacteroidetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
DTH2_k127_1237220_2	1392498.JQLH01000001_gene2438	7.645e-191	613.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,1HWWR@117743|Flavobacteriia,2PGCB@252356|Maribacter	976|Bacteroidetes	V	ABC transporter transmembrane region	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DTH2_k127_1237220_4	485918.Cpin_0796	1.8e-164	523.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DTH2_k127_1237220_15	929556.Solca_3455	1.076e-71	247.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DTH2_k127_1237220_8	755732.Fluta_2478	5.841e-116	376.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia,2PAHN@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DTH2_k127_1237220_11	1120966.AUBU01000002_gene2025	7.419e-101	336.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,47M4X@768503|Cytophagia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DTH2_k127_1237220_9	694427.Palpr_1328	1.095e-111	367.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,22WM5@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DTH2_k127_1237220_19	755732.Fluta_2474	2.093e-47	173.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,1I21V@117743|Flavobacteriia,2PAUD@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DTH2_k127_1237220_16	1122621.ATZA01000020_gene3982	3.048e-63	220.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DTH2_k127_1237220_7	1358423.N180_09440	1.34e-126	417.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DTH2_k127_1237220_13	743722.Sph21_5197	3.601e-84	284.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1IQUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
DTH2_k127_1237404_1	313606.M23134_05136	1.478e-20	103.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_1,LRR_8
DTH2_k127_1237404_0	1121912.AUHD01000003_gene3099	1.762e-83	283.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1HXMN@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
DTH2_k127_1267391_10	1122931.AUAE01000017_gene4288	2.774e-08	63.0	COG3637@1|root,COG3637@2|Bacteria,4NV08@976|Bacteroidetes,2FYJ1@200643|Bacteroidia,230YU@171551|Porphyromonadaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_1267391_3	1341181.FLJC2902T_28230	5.901e-113	383.0	COG0265@1|root,COG3291@1|root,COG4675@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,COG4675@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2P0S7@237|Flavobacterium	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
DTH2_k127_1267391_5	1408433.JHXV01000018_gene3795	1.229e-96	338.0	COG0265@1|root,COG3673@1|root,COG4412@1|root,COG0265@2|Bacteria,COG3673@2|Bacteria,COG4412@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2PA7S@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
DTH2_k127_1267391_8	1185876.BN8_06081	3.845e-42	169.0	COG0457@1|root,COG0457@2|Bacteria,4NMCQ@976|Bacteroidetes,47KHK@768503|Cytophagia	976|Bacteroidetes	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
DTH2_k127_1267391_2	1321779.HMPREF1984_00831	8.016e-140	458.0	COG1696@1|root,COG1696@2|Bacteria,3796N@32066|Fusobacteria	32066|Fusobacteria	M	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
DTH2_k127_1267391_1	945713.IALB_3057	2.722e-270	848.0	COG1505@1|root,COG1505@2|Bacteria	2|Bacteria	E	serine-type exopeptidase activity	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH2_k127_1267391_0	991.IW20_15685	9.876e-273	849.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia,2NUPC@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DTH2_k127_1267391_7	153721.MYP_2760	2.132e-85	298.0	COG3146@1|root,COG3146@2|Bacteria,4NI7H@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB_like
DTH2_k127_1267391_4	755732.Fluta_3281	1.618e-100	370.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB,VCBS
DTH2_k127_1267391_6	1408433.JHXV01000026_gene3014	2.053e-88	317.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,4NRDH@976|Bacteroidetes,1IIK5@117743|Flavobacteriia,2PBFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_1267391_9	755732.Fluta_2885	1.936e-19	104.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_126743_0	1124780.ANNU01000051_gene2062	0.0	1527.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH2_k127_126743_5	929556.Solca_2575	7.383e-20	90.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DTH2_k127_126743_1	362418.IW19_03425	1.539e-246	773.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,2NUW9@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DTH2_k127_126743_3	929562.Emtol_4277	5.998e-86	288.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,47KEA@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
DTH2_k127_126743_4	886379.AEWI01000030_gene300	5.916e-77	262.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,2FRYA@200643|Bacteroidia,3XJ8R@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_126743_2	468059.AUHA01000003_gene1421	9.253e-94	319.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1IQGQ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_13274_1	1484460.JSWG01000003_gene796	5.94e-165	534.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,1IITP@117743|Flavobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_13274_4	926692.AZYG01000096_gene1900	6.435e-102	350.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia	186801|Clostridia	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_13274_0	269798.CHU_2822	1.545e-172	550.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DTH2_k127_13274_5	1137281.D778_01983	8.821e-93	310.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_13274_3	926562.Oweho_0229	3.428e-117	391.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia,2PAFC@246874|Cryomorphaceae	976|Bacteroidetes	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_13274_2	153721.MYP_2041	5.004e-140	455.0	COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,47KRS@768503|Cytophagia	976|Bacteroidetes	E	Alanine dehydrogenase PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_1412828_8	243164.DET0736	5.877e-49	179.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi,34CMA@301297|Dehalococcoidia	301297|Dehalococcoidia	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
DTH2_k127_1412828_0	1123057.P872_20470	1.387e-286	888.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47TSB@768503|Cytophagia	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
DTH2_k127_1412828_4	1123248.KB893326_gene1432	1.485e-138	447.0	COG1071@1|root,COG1071@2|Bacteria,4NJMZ@976|Bacteroidetes,1IW7N@117747|Sphingobacteriia	976|Bacteroidetes	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DTH2_k127_1412828_3	1121875.KB907550_gene759	2.014e-156	499.0	COG0022@1|root,COG0022@2|Bacteria,4NFYK@976|Bacteroidetes	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_1412828_5	1237149.C900_03072	6.788e-118	390.0	COG0508@1|root,COG0508@2|Bacteria,4NE41@976|Bacteroidetes,47TKM@768503|Cytophagia	976|Bacteroidetes	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_1412828_9	1131812.JQMS01000001_gene1964	7.302e-28	116.0	COG0236@1|root,COG0236@2|Bacteria,4NWTZ@976|Bacteroidetes,1IBDJ@117743|Flavobacteriia	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH2_k127_1412828_2	1121904.ARBP01000001_gene5647	9.014e-168	532.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_1412828_1	485918.Cpin_1154	3.01e-285	886.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1IYHV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH2_k127_1412828_6	269798.CHU_3521	8.746e-117	389.0	COG2067@1|root,COG2067@2|Bacteria,4NFFF@976|Bacteroidetes,47NDV@768503|Cytophagia	976|Bacteroidetes	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
DTH2_k127_1412828_7	755732.Fluta_1309	9.382e-69	250.0	COG2272@1|root,COG2272@2|Bacteria,4PI06@976|Bacteroidetes,1IG13@117743|Flavobacteriia,2PB7F@246874|Cryomorphaceae	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
DTH2_k127_1470000_2	929562.Emtol_1901	1.447e-36	145.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,47NAK@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM ribosomal RNA small subunit methyltransferase RsmB	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
DTH2_k127_1470000_1	1094466.KQS_05220	5.063e-50	190.0	29ZGM@1|root,30MGC@2|Bacteria,4NNY9@976|Bacteroidetes,1I2DF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1470000_3	1317122.ATO12_01935	1.23e-28	120.0	COG0662@1|root,COG0662@2|Bacteria,4NVCS@976|Bacteroidetes,1IHUF@117743|Flavobacteriia,2YJQ6@290174|Aquimarina	976|Bacteroidetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MannoseP_isomer
DTH2_k127_1470000_0	313606.M23134_05475	0.0	1965.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
DTH2_k127_1475897_5	1408473.JHXO01000001_gene1960	1.388e-21	106.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes	976|Bacteroidetes	N	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
DTH2_k127_1475897_6	929556.Solca_2290	3.039e-13	74.0	COG0810@1|root,COG0810@2|Bacteria,4NWK2@976|Bacteroidetes,1IWQC@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_1475897_2	1313421.JHBV01000049_gene29	1.283e-146	471.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
DTH2_k127_1475897_8	216432.CA2559_12818	3.689e-05	53.0	COG3794@1|root,COG3794@2|Bacteria,4NNXS@976|Bacteroidetes,1I3WK@117743|Flavobacteriia	976|Bacteroidetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DTH2_k127_1475897_4	509635.N824_07920	2.604e-64	228.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
DTH2_k127_1475897_1	1168034.FH5T_08385	7.285e-163	540.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_1475897_0	929556.Solca_2664	0.0	1504.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_1475897_7	1123276.KB893245_gene1418	3.979e-08	69.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NGEP@976|Bacteroidetes,47NK0@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_1475897_3	153721.MYP_2132	3.959e-94	327.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_1488277_5	1408433.JHXV01000028_gene2156	5.305e-39	154.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_1488277_1	1408433.JHXV01000028_gene2156	1.992e-112	396.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_1488277_0	926562.Oweho_2942	1.481e-185	597.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia,2PAHE@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
DTH2_k127_1488277_4	1279009.ADICEAN_00376	4.288e-51	188.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
DTH2_k127_1488277_6	926562.Oweho_2941	1.824e-09	65.0	2E09A@1|root,32VWX@2|Bacteria,4NT9W@976|Bacteroidetes,1I9TI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1488277_3	153721.MYP_605	4.942e-60	215.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R3F@768503|Cytophagia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_1488277_2	1121904.ARBP01000002_gene6918	2.49e-107	357.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47UE3@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter C-terminal domain	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH2_k127_1522384_3	755732.Fluta_1284	1.759e-44	171.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_1522384_0	926562.Oweho_2741	0.0	1046.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,1I7EU@117743|Flavobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
DTH2_k127_1522384_2	1538644.KO02_07415	1.973e-74	255.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1IRUN@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_1522384_1	1250232.JQNJ01000001_gene2120	2.871e-104	344.0	COG1413@1|root,COG1413@2|Bacteria,4NJ2W@976|Bacteroidetes,1I005@117743|Flavobacteriia	976|Bacteroidetes	C	HEAT domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH2_k127_153789_0	1249975.JQLP01000005_gene1423	4.162e-191	612.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1HY9Z@117743|Flavobacteriia	976|Bacteroidetes	P	potassium uptake protein, TrkH family	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DTH2_k127_153789_1	1249975.JQLP01000005_gene1422	9.461e-94	312.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1HYTE@117743|Flavobacteriia	976|Bacteroidetes	P	COG0569 K transport systems NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DTH2_k127_1539302_8	755732.Fluta_0797	1.94e-82	289.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
DTH2_k127_1539302_9	762903.Pedsa_2075	1.022e-81	279.0	COG0500@1|root,COG0500@2|Bacteria,4NFKM@976|Bacteroidetes,1IPHK@117747|Sphingobacteriia	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
DTH2_k127_1539302_12	929556.Solca_2332	1.232e-68	241.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1IRVP@117747|Sphingobacteriia	976|Bacteroidetes	P	ZIP Zinc transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
DTH2_k127_1539302_13	760192.Halhy_3993	3.318e-60	212.0	COG1225@1|root,COG1225@2|Bacteria,4NMGU@976|Bacteroidetes,1IS08@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH2_k127_1539302_6	929556.Solca_0238	6.651e-104	340.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,1IPHX@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
DTH2_k127_1539302_19	1123276.KB893246_gene814	7.158e-22	104.0	COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,47MRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_1539302_14	755732.Fluta_2322	4.201e-54	192.0	COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,1I23U@117743|Flavobacteriia,2PAX5@246874|Cryomorphaceae	976|Bacteroidetes	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
DTH2_k127_1539302_18	1124780.ANNU01000024_gene3089	5.257e-31	129.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
DTH2_k127_1539302_2	1123277.KB893195_gene5586	6.648e-201	637.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_1539302_11	714943.Mucpa_2651	2.383e-69	244.0	COG0613@1|root,COG0613@2|Bacteria,4PMKK@976|Bacteroidetes,1IRJU@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD_2
DTH2_k127_1539302_17	1168289.AJKI01000011_gene642	6.684e-33	138.0	29N3N@1|root,33PNI@2|Bacteria,4P1TW@976|Bacteroidetes,2G20D@200643|Bacteroidia,3XIQT@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1539302_3	1358423.N180_12960	2.916e-188	593.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH2_k127_1539302_1	1453501.JELR01000001_gene2896	7.588e-204	652.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466AZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DTH2_k127_1539302_4	1321778.HMPREF1982_00173	5.773e-148	479.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,24AKU@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
DTH2_k127_1539302_7	1227739.Hsw_3425	2.857e-98	332.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DTH2_k127_1539302_0	1227739.Hsw_3426	3.767e-260	818.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_1539302_10	985255.APHJ01000035_gene7	4.36e-72	250.0	COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia,2P6HK@244698|Gillisia	976|Bacteroidetes	S	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
DTH2_k127_1539302_15	929556.Solca_2089	7.217e-44	164.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_1539302_16	313606.M23134_06732	4.092e-42	158.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,47PP3@768503|Cytophagia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
DTH2_k127_1539302_5	1408473.JHXO01000006_gene1161	4.049e-106	359.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,2FMTF@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
DTH2_k127_1539302_22	714943.Mucpa_6090	1.482e-10	70.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_1539302_20	886377.Murru_1970	1.359e-18	94.0	28PIV@1|root,2ZC8P@2|Bacteria,4NGE2@976|Bacteroidetes,1I08D@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
DTH2_k127_1539302_21	755732.Fluta_2754	6.578e-11	66.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia,2PB5T@246874|Cryomorphaceae	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
DTH2_k127_159681_8	714943.Mucpa_3247	8.235e-51	184.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1IRJ2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
DTH2_k127_159681_7	927658.AJUM01000037_gene2293	3.995e-68	241.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DTH2_k127_159681_3	1120968.AUBX01000011_gene3236	2.31e-157	506.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47K4Z@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH2_k127_159681_6	755732.Fluta_2596	7.529e-70	252.0	COG3920@1|root,COG3920@2|Bacteria,4NP4X@976|Bacteroidetes,1I22K@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2,TPR_8
DTH2_k127_159681_4	153721.MYP_243	1.236e-87	310.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_159681_5	1408473.JHXO01000011_gene3070	1.985e-77	267.0	COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,2FXYF@200643|Bacteroidia	976|Bacteroidetes	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH2_k127_159681_9	869213.JCM21142_104477	2.143e-39	156.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,47SCF@768503|Cytophagia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
DTH2_k127_159681_1	1121904.ARBP01000001_gene5937	1.87e-218	702.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_159681_0	926562.Oweho_1295	5.258e-224	718.0	COG1629@1|root,COG4771@2|Bacteria,4PPAD@976|Bacteroidetes	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_159681_2	926562.Oweho_0147	5.119e-186	586.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,2PAB9@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DTH2_k127_1602710_1	1122176.KB903539_gene1332	1.508e-83	296.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1IRI6@117747|Sphingobacteriia	976|Bacteroidetes	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DTH2_k127_1602710_0	1313421.JHBV01000020_gene5288	4.328e-88	313.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	oppA_5	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
DTH2_k127_160385_1	1408433.JHXV01000027_gene3728	3.889e-171	563.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_160385_0	1408433.JHXV01000027_gene3728	3.856e-291	934.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_1663877_7	1122176.KB903543_gene661	1.373e-40	157.0	COG1629@1|root,COG4771@2|Bacteria,4PN7E@976|Bacteroidetes,1J0MG@117747|Sphingobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_1663877_6	1121957.ATVL01000006_gene3301	3.975e-42	169.0	2DX8D@1|root,343UE@2|Bacteria,4P6Q1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1663877_2	926562.Oweho_2268	3.266e-97	330.0	COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1HX5B@117743|Flavobacteriia,2PA8I@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
DTH2_k127_1663877_0	1123399.AQVE01000008_gene1510	1.948e-152	486.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,1TA6N@1236|Gammaproteobacteria,4634I@72273|Thiotrichales	72273|Thiotrichales	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
DTH2_k127_1663877_8	653045.Strvi_0289	4.748e-36	138.0	COG3460@1|root,COG3460@2|Bacteria,2IKMJ@201174|Actinobacteria	201174|Actinobacteria	Q	Phenylacetate-CoA oxygenase	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
DTH2_k127_1663877_3	1121930.AQXG01000008_gene188	4.148e-89	300.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes	976|Bacteroidetes	S	Phenylacetate-CoA oxygenase	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
DTH2_k127_1663877_5	1313421.JHBV01000003_gene602	1.335e-58	207.0	COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes,1IXUP@117747|Sphingobacteriia	976|Bacteroidetes	L	Pfam:DUF59	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
DTH2_k127_1663877_4	755732.Fluta_2350	5.227e-75	265.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria,4P5PY@976|Bacteroidetes	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF
DTH2_k127_1663877_1	1443665.JACA01000056_gene3223	8.525e-100	331.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia,2YINB@290174|Aquimarina	976|Bacteroidetes	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
DTH2_k127_1663877_9	1227739.Hsw_1456	3.646e-20	93.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,47XHJ@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DTH2_k127_1702148_21	1121904.ARBP01000003_gene6407	3.593e-10	64.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_1702148_13	1122176.KB903571_gene4786	3.52e-62	237.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_16,TPR_2,TPR_8
DTH2_k127_1702148_1	1408473.JHXO01000010_gene3580	9.345e-201	670.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia	976|Bacteroidetes	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_1702148_11	929556.Solca_4180	1.015e-66	229.0	COG2185@1|root,COG2185@2|Bacteria,4NNXP@976|Bacteroidetes,1ISKU@117747|Sphingobacteriia	976|Bacteroidetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
DTH2_k127_1702148_8	1122225.AULQ01000002_gene583	6.424e-112	368.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1HWQA@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DTH2_k127_1702148_2	243233.MCA1772	6.444e-160	518.0	COG2244@1|root,COG2244@2|Bacteria,1R512@1224|Proteobacteria,1RZ0F@1236|Gammaproteobacteria,1XE8D@135618|Methylococcales	135618|Methylococcales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_1702148_12	1121896.JMLU01000022_gene2030	1.478e-66	229.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,1I1AC@117743|Flavobacteriia,2NVXP@237|Flavobacterium	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
DTH2_k127_1702148_3	926549.KI421517_gene1852	5.881e-150	480.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DTH2_k127_1702148_7	468059.AUHA01000002_gene1188	1.281e-120	408.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IR0N@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
DTH2_k127_1702148_18	555500.I215_00915	2.551e-27	122.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,1HX5K@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
DTH2_k127_1702148_9	929556.Solca_4343	1.275e-99	339.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_1702148_19	1538644.KO02_18815	4.307e-15	77.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1IUEK@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_1702148_0	1408433.JHXV01000007_gene2833	3.799e-201	637.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia,2PA8A@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH2_k127_1702148_5	926562.Oweho_2456	1.028e-133	442.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2PACQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
DTH2_k127_1702148_17	1408433.JHXV01000002_gene339	5.724e-30	125.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
DTH2_k127_1702148_22	1120951.AUBG01000010_gene1892	8.175e-08	63.0	COG4886@1|root,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I4F0@117743|Flavobacteriia	976|Bacteroidetes	S	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1702148_16	506534.Rhein_1562	5.49e-32	137.0	COG1835@1|root,COG1835@2|Bacteria,1N5D8@1224|Proteobacteria,1RS5Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_1702148_6	1313301.AUGC01000001_gene1483	4.649e-130	426.0	COG0626@1|root,COG0626@2|Bacteria,4NH38@976|Bacteroidetes	976|Bacteroidetes	E	COGs COG0626 Cystathionine beta-lyase cystathionine gamma-synthase	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
DTH2_k127_1702148_14	1123057.P872_14600	1.823e-60	210.0	COG3169@1|root,COG3169@2|Bacteria,4NQH4@976|Bacteroidetes,47QJ9@768503|Cytophagia	976|Bacteroidetes	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
DTH2_k127_1702148_10	1408433.JHXV01000015_gene1728	3.045e-98	329.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia,2PAS1@246874|Cryomorphaceae	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_1724387_0	153721.MYP_1143	1.446e-279	869.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,47KA7@768503|Cytophagia	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DTH2_k127_1740082_3	1035193.HMPREF9073_00818	1.68e-05	47.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia,1EQB1@1016|Capnocytophaga	976|Bacteroidetes	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
DTH2_k127_1740082_1	929556.Solca_1904	7.532e-102	334.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_1740082_0	762903.Pedsa_1064	3.622e-175	570.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
DTH2_k127_1740082_2	929562.Emtol_1812	4.898e-15	81.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
DTH2_k127_1769778_3	313606.M23134_06262	1.433e-115	396.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	srrB	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,HAMP,SpoIIE,TPR_12,TPR_8,Y_Y_Y,dCache_1
DTH2_k127_1769778_5	755732.Fluta_3847	7.889e-89	321.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
DTH2_k127_1769778_4	468059.AUHA01000002_gene784	8.002e-96	318.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1IPXK@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
DTH2_k127_1769778_11	1121875.KB907556_gene590	2.992e-16	79.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,1I5MP@117743|Flavobacteriia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
DTH2_k127_1769778_9	1121373.KB903625_gene3229	2.743e-22	99.0	COG4829@1|root,COG4829@2|Bacteria,4NS7J@976|Bacteroidetes,47RN0@768503|Cytophagia	976|Bacteroidetes	Q	muconolactone delta-isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MIase
DTH2_k127_1769778_6	765869.BDW_03455	3.618e-62	222.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,42Q1N@68525|delta/epsilon subdivisions,2WK3A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
DTH2_k127_1769778_7	1121957.ATVL01000007_gene2002	1.099e-41	158.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	slyA	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
DTH2_k127_1769778_1	643867.Ftrac_1079	1.273e-147	477.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,47JD1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM flavoprotein, HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH2_k127_1769778_10	143224.JQMD01000002_gene2185	1.592e-17	88.0	COG0526@1|root,COG0526@2|Bacteria,4NS1W@976|Bacteroidetes,1I3EA@117743|Flavobacteriia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
DTH2_k127_1769778_0	1121904.ARBP01000001_gene5377	1.133e-170	546.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_1769778_8	929556.Solca_4383	2.517e-22	99.0	COG5512@1|root,COG5512@2|Bacteria,4NSDR@976|Bacteroidetes,1ITAK@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
DTH2_k127_1769778_2	1408473.JHXO01000008_gene2781	7.55e-127	414.0	COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,2FMHP@200643|Bacteroidia	976|Bacteroidetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_15,SMC_N
DTH2_k127_1797546_6	395493.BegalDRAFT_3388	3.709e-90	302.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RWCC@1236|Gammaproteobacteria,460AQ@72273|Thiotrichales	72273|Thiotrichales	M	UDP-N-acetylglucosamine 2-epimerase	-	-	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DTH2_k127_1797546_8	395493.BegalDRAFT_3387	1.197e-76	267.0	COG4552@1|root,COG4552@2|Bacteria,1NJ0B@1224|Proteobacteria	1224|Proteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
DTH2_k127_1797546_3	929556.Solca_4307	3.684e-126	411.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1IRJN@117747|Sphingobacteriia	976|Bacteroidetes	M	synthase	neuB	-	2.5.1.101,2.5.1.132,2.5.1.56	ko:K01654,ko:K18430,ko:K21279	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
DTH2_k127_1797546_2	326298.Suden_0593	1.089e-165	528.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MJD@68525|delta/epsilon subdivisions,2YMVU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_1797546_1	929556.Solca_4304	1.736e-171	542.0	COG0451@1|root,COG0451@2|Bacteria,4NIMH@976|Bacteroidetes,1IZ1A@117747|Sphingobacteriia	976|Bacteroidetes	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
DTH2_k127_1797546_4	714943.Mucpa_3746	4.034e-114	385.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1IP8T@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_1797546_0	1408473.JHXO01000010_gene3748	3.177e-191	626.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH2_k127_1797546_5	1453500.AT05_04385	9.998e-98	327.0	COG3751@1|root,COG3751@2|Bacteria,4NI8F@976|Bacteroidetes,1I4Z2@117743|Flavobacteriia	976|Bacteroidetes	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
DTH2_k127_1797546_9	1173024.KI912148_gene2531	1.691e-70	247.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_1797546_7	926562.Oweho_1463	8.806e-80	278.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DTH2_k127_1797546_11	1313421.JHBV01000041_gene3688	4.677e-15	78.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	Hydrolase_4,UPF0227
DTH2_k127_1828496_7	755732.Fluta_3635	0.0002864	53.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes,1ICNQ@117743|Flavobacteriia,2PBCJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1828496_2	1538644.KO02_12920	1.608e-48	175.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH2_k127_1828496_1	929556.Solca_0526	1.392e-129	420.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1IRJS@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH2_k127_1828496_4	1121373.KB903624_gene2442	1.94e-30	121.0	COG3530@1|root,COG3530@2|Bacteria,4NUSP@976|Bacteroidetes,47RWJ@768503|Cytophagia	976|Bacteroidetes	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
DTH2_k127_1828496_3	592029.DDD_1268	2.118e-36	159.0	COG2885@1|root,COG2885@2|Bacteria,4NECX@976|Bacteroidetes,1HZVB@117743|Flavobacteriia	976|Bacteroidetes	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
DTH2_k127_1828496_0	1121957.ATVL01000008_gene4046	3.284e-236	738.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH2_k127_1828496_5	742727.HMPREF9447_02444	1.141e-09	64.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,2FPFD@200643|Bacteroidia,4AKKZ@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG14459 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
DTH2_k127_1865233_0	871968.DESME_07755	2.235e-71	258.0	COG1228@1|root,COG1228@2|Bacteria,1W6UF@1239|Firmicutes,24MIJ@186801|Clostridia	186801|Clostridia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH2_k127_1865233_1	536227.CcarbDRAFT_2348	1.291e-45	177.0	COG3976@1|root,COG3976@2|Bacteria,1VFG0@1239|Firmicutes,24RHT@186801|Clostridia,36MVQ@31979|Clostridiaceae	186801|Clostridia	S	PFAM FMN-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
DTH2_k127_1865233_3	491952.Mar181_1355	4.165e-05	46.0	COG0702@1|root,COG0702@2|Bacteria,1RDKF@1224|Proteobacteria,1S0A1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
DTH2_k127_1865233_2	491952.Mar181_1355	1.01e-10	66.0	COG0702@1|root,COG0702@2|Bacteria,1RDKF@1224|Proteobacteria,1S0A1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
DTH2_k127_1865233_4	1246626.BleG1_3210	0.0002984	50.0	COG1708@1|root,COG1708@2|Bacteria,1UBTE@1239|Firmicutes,4IN8P@91061|Bacilli,1ZN1C@1386|Bacillus	91061|Bacilli	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
DTH2_k127_1877666_12	1408433.JHXV01000005_gene2237	1.445e-61	224.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1877666_9	929562.Emtol_2961	7.758e-126	411.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,47K2G@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
DTH2_k127_1877666_13	1168034.FH5T_21280	1.899e-61	214.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,2FR57@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
DTH2_k127_1877666_10	714943.Mucpa_5210	1.075e-124	405.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH2_k127_1877666_14	929556.Solca_0533	6.465e-30	124.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1ITXJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1877666_11	1408473.JHXO01000005_gene1492	4.5e-76	258.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,2FP0F@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_1877666_4	1227739.Hsw_1685	3.203e-176	555.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,47JQN@768503|Cytophagia	976|Bacteroidetes	G	PFAM Transketolase, C-terminal domain	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_1877666_8	926562.Oweho_1341	7.057e-136	447.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
DTH2_k127_1877666_7	592029.DDD_0219	1.051e-143	460.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1HWZM@117743|Flavobacteriia,3HJCK@363408|Nonlabens	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DTH2_k127_1877666_3	762903.Pedsa_2092	2.81e-184	581.0	COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1IPTY@117747|Sphingobacteriia	976|Bacteroidetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DTH2_k127_1877666_1	1341181.FLJC2902T_25800	1.057e-296	919.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia,2NTTJ@237|Flavobacterium	976|Bacteroidetes	L	DNA Topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_1877666_0	1453498.LG45_08685	0.0	1114.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2NUEE@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH2_k127_1877666_6	1313421.JHBV01000044_gene2957	2.864e-150	504.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
DTH2_k127_1877666_5	553177.CAPSP0001_2515	1.578e-155	497.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1HWSG@117743|Flavobacteriia,1EQ9Q@1016|Capnocytophaga	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_1877666_2	1408473.JHXO01000004_gene166	3.188e-234	778.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
DTH2_k127_1882476_8	468059.AUHA01000002_gene664	1.547e-103	338.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1IQF9@117747|Sphingobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH2_k127_1882476_4	1408473.JHXO01000001_gene2033	5.442e-154	503.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FP0Y@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_1882476_13	153721.MYP_4755	2.063e-77	261.0	COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia	976|Bacteroidetes	F	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
DTH2_k127_1882476_0	1131812.JQMS01000001_gene40	0.0	1022.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DTH2_k127_1882476_6	1450525.JATV01000001_gene2571	1.411e-131	434.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia,2NSBZ@237|Flavobacterium	976|Bacteroidetes	EF	Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
DTH2_k127_1882476_16	743722.Sph21_5155	6.232e-57	205.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IRTD@117747|Sphingobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DTH2_k127_1882476_12	755732.Fluta_1719	2.535e-78	265.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia,2PASN@246874|Cryomorphaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DTH2_k127_1882476_18	1454007.JAUG01000139_gene4166	5.903e-43	169.0	COG2374@1|root,COG2911@1|root,COG3210@1|root,COG4733@1|root,COG5492@1|root,COG2374@2|Bacteria,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	LTD
DTH2_k127_1882476_1	1178825.ALIH01000001_gene2271	9.774e-247	775.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DTH2_k127_1882476_5	929556.Solca_0272	5.29e-148	474.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
DTH2_k127_1882476_11	335543.Sfum_2239	4.657e-83	290.0	COG0859@1|root,COG0859@2|Bacteria,1PQIG@1224|Proteobacteria,42MUM@68525|delta/epsilon subdivisions,2WPZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
DTH2_k127_1882476_14	1289135.A966_01903	3.046e-68	241.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
DTH2_k127_1882476_2	1267211.KI669560_gene577	7.623e-241	757.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_1882476_10	1313421.JHBV01000043_gene3214	5.025e-93	315.0	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes	976|Bacteroidetes	M	Bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
DTH2_k127_1882476_7	1123057.P872_11400	7.179e-106	348.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DTH2_k127_1882476_20	927677.ALVU02000008_gene27	8.946e-24	113.0	COG2850@1|root,COG2850@2|Bacteria,1GEFT@1117|Cyanobacteria	1117|Cyanobacteria	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
DTH2_k127_1882476_9	1189612.A33Q_2567	2.596e-94	317.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
DTH2_k127_1882476_17	1279009.ADICEAN_03098	1.553e-45	169.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,47KPZ@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_1882476_3	929562.Emtol_4231	6.284e-191	604.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,47MVE@768503|Cytophagia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DTH2_k127_1882476_15	880071.Fleli_0671	1.629e-59	211.0	COG1187@1|root,COG1187@2|Bacteria,4NM4U@976|Bacteroidetes,47PFZ@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH2_k127_1882476_21	1121957.ATVL01000006_gene3008	4.328e-17	85.0	COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,47Y2W@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_9,Reg_prop,Response_reg
DTH2_k127_1885205_1	1408433.JHXV01000017_gene1629	1.122e-240	757.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
DTH2_k127_1885205_7	1408433.JHXV01000017_gene1628	4.06e-30	124.0	290ZX@1|root,2ZNMM@2|Bacteria,4P891@976|Bacteroidetes,1ICSI@117743|Flavobacteriia,2PC01@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1885205_5	755732.Fluta_3556	1.391e-57	211.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1885205_3	865937.Gilli_3349	1.794e-137	449.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia,2P60V@244698|Gillisia	976|Bacteroidetes	L	THUMP	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
DTH2_k127_1885205_2	468059.AUHA01000002_gene823	1.845e-141	455.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1IPUF@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
DTH2_k127_1885205_4	153721.MYP_4660	7.88e-64	226.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_1885205_0	385682.AFSL01000023_gene2125	3.677e-263	836.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,2FN6Z@200643|Bacteroidia,3XJEX@558415|Marinilabiliaceae	976|Bacteroidetes	L	helicase superfamily c-terminal domain	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DTH2_k127_1885205_6	1408473.JHXO01000001_gene2242	3.071e-38	151.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,2G096@200643|Bacteroidia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
DTH2_k127_191686_0	1408433.JHXV01000008_gene157	1.281e-106	348.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1HX4M@117743|Flavobacteriia,2PA6Q@246874|Cryomorphaceae	976|Bacteroidetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
DTH2_k127_191686_1	1250232.JQNJ01000001_gene1986	3.601e-84	284.0	COG2940@1|root,COG2940@2|Bacteria,4NM5I@976|Bacteroidetes,1I1ME@117743|Flavobacteriia	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
DTH2_k127_191686_2	1313421.JHBV01000003_gene649	2.49e-25	108.0	COG0596@1|root,COG0703@1|root,COG0596@2|Bacteria,COG0703@2|Bacteria,4PNUJ@976|Bacteroidetes,1IXQ1@117747|Sphingobacteriia	976|Bacteroidetes	F	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
DTH2_k127_1945459_3	1189612.A33Q_2560	1.205e-98	329.0	COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47JB2@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_1945459_2	926549.KI421517_gene2587	2.446e-157	506.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH2_k127_1945459_1	714943.Mucpa_6521	6.396e-216	687.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
DTH2_k127_1945459_9	1121887.AUDK01000029_gene2536	3.938e-06	55.0	2E7ZI@1|root,30SND@2|Bacteria,4PABN@976|Bacteroidetes,1ID0S@117743|Flavobacteriia,2NWQX@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1945459_0	926559.JoomaDRAFT_0178	1.342e-307	955.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DTH2_k127_1945459_7	706436.HMPREF9074_08404	6.108e-34	142.0	COG5263@1|root,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,1HX7Q@117743|Flavobacteriia,1ETIA@1016|Capnocytophaga	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_1945459_5	1121889.AUDM01000007_gene967	1.234e-80	275.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia,2NTHH@237|Flavobacterium	976|Bacteroidetes	E	catalyzes the conversion of shikimate to 3-dehydroshikimate	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
DTH2_k127_1945459_6	1121481.AUAS01000008_gene3116	4.294e-73	252.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,47NAX@768503|Cytophagia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH2_k127_1945459_8	1121904.ARBP01000001_gene5612	2.296e-28	118.0	COG0607@1|root,COG0607@2|Bacteria,4NRFK@976|Bacteroidetes,47RKB@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	naoX	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_1945459_4	1408433.JHXV01000026_gene3043	2.31e-85	286.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IMQP@117743|Flavobacteriia,2PBFH@246874|Cryomorphaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
DTH2_k127_19514_0	755732.Fluta_1254	1.665e-106	366.0	COG2208@1|root,COG5002@1|root,COG2208@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	srrB	-	2.7.13.3	ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,HAMP,SpoIIE,dCache_1
DTH2_k127_19514_1	1408433.JHXV01000010_gene565	5.78e-37	145.0	COG2208@1|root,COG2208@2|Bacteria,4PPWM@976|Bacteroidetes,1IKWE@117743|Flavobacteriia,2PBIK@246874|Cryomorphaceae	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
DTH2_k127_1952732_1	1408813.AYMG01000007_gene4338	8.107e-179	568.0	COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes,1IR28@117747|Sphingobacteriia	976|Bacteroidetes	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
DTH2_k127_1952732_2	714943.Mucpa_1559	3.476e-145	473.0	COG2211@1|root,COG2211@2|Bacteria,4NNU9@976|Bacteroidetes,1ISCZ@117747|Sphingobacteriia	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
DTH2_k127_1952732_0	1123248.KB893321_gene544	1.636e-271	858.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IW7P@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_1952732_4	1123248.KB893337_gene2581	3.312e-40	160.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes,1IUAK@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
DTH2_k127_1952732_3	580332.Slit_1412	2.725e-41	155.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,44VS2@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
DTH2_k127_1971010_6	1453500.AT05_09305	1.594e-69	248.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_1971010_7	760192.Halhy_4325	3.322e-31	136.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_1971010_10	929703.KE386491_gene3965	2.196e-07	65.0	COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_1971010_3	1121373.KB903632_gene507	3.046e-129	451.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3,PQQ_2
DTH2_k127_1971010_5	1408473.JHXO01000006_gene1182	2.79e-77	265.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,2FM71@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
DTH2_k127_1971010_4	1408473.JHXO01000006_gene1183	3.067e-83	290.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,2FP24@200643|Bacteroidia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_1971010_0	1286632.P278_06400	0.0	1114.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DTH2_k127_1971010_9	313590.MED134_01250	2.917e-18	86.0	2E3YH@1|root,32YVH@2|Bacteria,4NWGM@976|Bacteroidetes,1I552@117743|Flavobacteriia,37FFS@326319|Dokdonia	976|Bacteroidetes	S	Bacterial inner membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
DTH2_k127_1971010_2	1469557.JSWF01000025_gene1389	1.563e-167	535.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia	976|Bacteroidetes	M	glucose-1-phosphate thymidylyltransferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
DTH2_k127_1971010_1	1121899.Q764_01135	2.429e-261	821.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia,2NTVT@237|Flavobacterium	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH2_k127_1981125_2	1336803.PHEL49_0242	4.617e-60	218.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia,3VW9G@52959|Polaribacter	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
DTH2_k127_1981125_0	1122176.KB903565_gene3321	7.295e-122	410.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_1981125_3	1121007.AUML01000016_gene258	3.603e-07	63.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1INA7@117743|Flavobacteriia,2YJ4W@290174|Aquimarina	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,MAM,PepSY,Peptidase_M4,Peptidase_M4_C,fn3
DTH2_k127_1981125_1	1341155.FSS13T_09120	1.014e-72	256.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia,2NU0J@237|Flavobacterium	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
DTH2_k127_2000207_0	714943.Mucpa_5159	4.805e-200	633.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1IR7Y@117747|Sphingobacteriia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DTH2_k127_2000207_2	398720.MED217_01755	6.003e-73	251.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia,2XJ8A@283735|Leeuwenhoekiella	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
DTH2_k127_2000207_6	709991.Odosp_2293	6.199e-06	56.0	COG0457@1|root,COG0457@2|Bacteria,4P45T@976|Bacteroidetes,2FYEG@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2000207_1	869213.JCM21142_72668	4.631e-133	444.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_2000207_3	313594.PI23P_02642	1.465e-72	250.0	COG0801@1|root,COG1428@1|root,COG0801@2|Bacteria,COG1428@2|Bacteria,4NGE8@976|Bacteroidetes,1HWTH@117743|Flavobacteriia,3VWA9@52959|Polaribacter	976|Bacteroidetes	FH	Thymidylate kinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
DTH2_k127_2000207_4	1123248.KB893359_gene2070	5.815e-43	162.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,1IT8Z@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
DTH2_k127_2000207_5	886293.Sinac_1023	3.115e-39	158.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
DTH2_k127_2006570_0	1313421.JHBV01000029_gene1873	1.059e-206	713.0	COG3291@1|root,COG3291@2|Bacteria,4PHX4@976|Bacteroidetes,1IXHW@117747|Sphingobacteriia	976|Bacteroidetes	N	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_2006570_4	1408433.JHXV01000015_gene1755	3.54e-22	115.0	COG4386@1|root,COG5384@1|root,COG4386@2|Bacteria,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes,1IKB1@117743|Flavobacteriia	976|Bacteroidetes	J	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,TSP_3
DTH2_k127_2006570_2	1408433.JHXV01000004_gene3380	8.027e-97	325.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia,2PBE9@246874|Cryomorphaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_2006570_1	929556.Solca_2370	2.709e-126	428.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IS3H@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_2011288_1	880071.Fleli_3872	4.21e-113	369.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,47JF0@768503|Cytophagia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
DTH2_k127_2011288_8	1278073.MYSTI_03344	5.337e-17	96.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WMM2@28221|Deltaproteobacteria,2Z1Q8@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2011288_7	714943.Mucpa_0108	4.825e-29	128.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3868,OmpA
DTH2_k127_2011288_2	1380384.JADN01000006_gene2412	2.357e-96	322.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DTH2_k127_2011288_5	1239962.C943_02291	2.928e-73	252.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
DTH2_k127_2011288_3	485917.Phep_3661	1.962e-92	316.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1IPIJ@117747|Sphingobacteriia	976|Bacteroidetes	O	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
DTH2_k127_2011288_0	929556.Solca_4417	7.151e-129	421.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1IRI6@117747|Sphingobacteriia	976|Bacteroidetes	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DTH2_k127_2011288_4	575590.HMPREF0156_00244	3.391e-92	309.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
DTH2_k127_2011288_6	1041826.FCOL_07300	4.52e-65	228.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia,2NTSR@237|Flavobacterium	976|Bacteroidetes	J	ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
DTH2_k127_2016829_10	1122605.KB893634_gene4208	4.646e-20	91.0	COG0457@1|root,COG0457@2|Bacteria,4NI5H@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
DTH2_k127_2016829_5	459349.CLOAM0690	1.194e-52	194.0	COG1028@1|root,COG1028@2|Bacteria	459349.CLOAM0690|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2016829_8	1270196.JCKI01000003_gene2098	1.2e-35	138.0	COG2456@1|root,COG2456@2|Bacteria,4NSNR@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
DTH2_k127_2016829_4	1185876.BN8_06280	8.701e-84	284.0	COG1216@1|root,COG1216@2|Bacteria,4NETR@976|Bacteroidetes,47NDP@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_2016829_3	929556.Solca_1910	2.258e-143	460.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,1INUR@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
DTH2_k127_2016829_0	886379.AEWI01000023_gene8	1.666e-319	992.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,3XJ41@558415|Marinilabiliaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
DTH2_k127_2016829_6	1358423.N180_11180	9.342e-51	184.0	COG1522@1|root,COG1522@2|Bacteria,4PJQJ@976|Bacteroidetes,1IYS0@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DTH2_k127_2016829_1	1296416.JACB01000064_gene5021	2.3e-184	584.0	COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,1HXIF@117743|Flavobacteriia,2YH0J@290174|Aquimarina	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH2_k127_2016829_2	929556.Solca_4096	9.103e-157	504.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1INTB@117747|Sphingobacteriia	976|Bacteroidetes	S	amidohydrolase	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_2016829_9	1121899.Q764_06910	2.053e-33	132.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes,1I2UM@117743|Flavobacteriia,2NWMD@237|Flavobacterium	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_2016829_7	1434325.AZQN01000002_gene878	4.056e-36	139.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,47KAC@768503|Cytophagia	976|Bacteroidetes	MU	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_2089073_2	1168289.AJKI01000008_gene680	3.198e-50	185.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia,3XJCY@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DTH2_k127_2089073_4	1550091.JROE01000008_gene3672	4.72e-16	81.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1ITBU@117747|Sphingobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
DTH2_k127_2089073_0	391596.PBAL39_06781	4.464e-133	444.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_2089073_1	153721.MYP_1941	2.692e-97	324.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47KCT@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH2_k127_2089073_3	700598.Niako_2729	2.584e-30	123.0	COG0596@1|root,COG0596@2|Bacteria,4PNUJ@976|Bacteroidetes,1IXQ1@117747|Sphingobacteriia	976|Bacteroidetes	F	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
DTH2_k127_2102220_0	1168034.FH5T_03525	7.786e-129	426.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_2102220_2	1168034.FH5T_03520	1.142e-48	187.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2102220_1	926562.Oweho_1845	5.297e-67	237.0	COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1I785@117743|Flavobacteriia,2PAYX@246874|Cryomorphaceae	976|Bacteroidetes	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
DTH2_k127_2121944_5	1453500.AT05_00860	1.432e-19	101.0	COG1449@1|root,COG3867@1|root,COG1449@2|Bacteria,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C,Glyco_hydro_53,Glyco_hydro_57,He_PIG,RicinB_lectin_2,SLH
DTH2_k127_2121944_3	391598.FBBAL38_09852	5.536e-95	332.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DTH2_k127_2121944_4	1392498.JQLH01000001_gene3225	1.835e-49	181.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia,2PHG3@252356|Maribacter	976|Bacteroidetes	F	Cytidine and deoxycytidylate deaminase zinc-binding region	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
DTH2_k127_2121944_1	1358423.N180_06985	2.875e-151	484.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DTH2_k127_2121944_0	388413.ALPR1_15254	2.546e-194	619.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_2121944_2	1202532.FF52_13881	3.352e-136	439.0	COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1I0YW@117743|Flavobacteriia,2NSZZ@237|Flavobacterium	976|Bacteroidetes	EGP	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
DTH2_k127_21705_3	929562.Emtol_1522	2.645e-224	698.0	COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia	976|Bacteroidetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DTH2_k127_21705_20	926562.Oweho_1476	7.452e-18	84.0	COG0690@1|root,COG0690@2|Bacteria,4PFHS@976|Bacteroidetes,1IC4N@117743|Flavobacteriia,2PB91@246874|Cryomorphaceae	976|Bacteroidetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
DTH2_k127_21705_10	742817.HMPREF9449_02965	9.474e-80	269.0	COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,2FNJ6@200643|Bacteroidia,22XKN@171551|Porphyromonadaceae	976|Bacteroidetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
DTH2_k127_21705_13	929556.Solca_0419	6.971e-71	241.0	COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,1IRUT@117747|Sphingobacteriia	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DTH2_k127_21705_7	1517682.HW49_07045	3.238e-108	354.0	COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia,22X02@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DTH2_k127_21705_17	860228.Ccan_16880	4.894e-48	177.0	COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,1HXJG@117743|Flavobacteriia,1EQTT@1016|Capnocytophaga	976|Bacteroidetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DTH2_k127_21705_16	880526.KE386488_gene996	1.109e-49	179.0	COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae	976|Bacteroidetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DTH2_k127_21705_1	755732.Fluta_2160	0.0	2108.0	COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1HXXA@117743|Flavobacteriia,2PAEA@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DTH2_k127_21705_0	743722.Sph21_2407	0.0	2224.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1IP5J@117747|Sphingobacteriia	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DTH2_k127_21705_18	468059.AUHA01000006_gene2837	1.111e-43	160.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
DTH2_k127_21705_4	984262.SGRA_2848	1.149e-145	470.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,1IQHU@117747|Sphingobacteriia	976|Bacteroidetes	E	Aminopeptidase	pepC	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
DTH2_k127_21705_22	385682.AFSL01000012_gene2827	4.412e-08	64.0	COG0457@1|root,COG0457@2|Bacteria,4NHH0@976|Bacteroidetes,2FP90@200643|Bacteroidia,3XJJE@558415|Marinilabiliaceae	976|Bacteroidetes	S	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_16
DTH2_k127_21705_19	307480.IW16_08770	8.925e-25	108.0	2E4AP@1|root,32Z6C@2|Bacteria,4NWDP@976|Bacteroidetes,1I55P@117743|Flavobacteriia,3ZRMH@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_21705_12	313606.M23134_05065	3.382e-72	256.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,4PME5@976|Bacteroidetes,47TNB@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
DTH2_k127_21705_6	857087.Metme_2849	4.302e-110	360.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,1RMT3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	ygdL	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
DTH2_k127_21705_15	1229487.AMYW01000043_gene3672	5.482e-52	191.0	COG0084@1|root,COG0084@2|Bacteria,4NSGW@976|Bacteroidetes,1I2AW@117743|Flavobacteriia,2NT8M@237|Flavobacterium	976|Bacteroidetes	L	hydrolase, TatD	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH2_k127_21705_5	929556.Solca_1923	6.407e-134	430.0	COG2013@1|root,COG2013@2|Bacteria,4NFNA@976|Bacteroidetes,1IW51@117747|Sphingobacteriia	976|Bacteroidetes	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
DTH2_k127_21705_2	926549.KI421517_gene3736	0.0	1858.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
DTH2_k127_21705_8	1121904.ARBP01000003_gene6466	1.126e-92	315.0	COG0204@1|root,COG4324@1|root,COG0204@2|Bacteria,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia	976|Bacteroidetes	I	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
DTH2_k127_21705_14	869213.JCM21142_41957	6.661e-54	199.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia	976|Bacteroidetes	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_21705_11	1233951.IO90_09205	2.967e-74	254.0	28N3K@1|root,2ZB98@2|Bacteria,4NKYB@976|Bacteroidetes,1HYC2@117743|Flavobacteriia,3HH3G@358033|Chryseobacterium	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
DTH2_k127_21705_21	1137281.D778_01509	5.744e-13	72.0	2E43R@1|root,32Z02@2|Bacteria,4NVFS@976|Bacteroidetes,1I51B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_21705_9	1121904.ARBP01000009_gene4266	9.797e-82	279.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DTH2_k127_2188553_2	700598.Niako_7268	5.842e-53	193.0	COG0438@1|root,COG0438@2|Bacteria,4NF7J@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
DTH2_k127_2188553_1	1121935.AQXX01000117_gene5104	9.534e-54	193.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,1SQYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2188553_3	985255.APHJ01000019_gene694	2.632e-07	52.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2188553_0	1250005.PHEL85_1678	1.216e-61	219.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia,3VVFR@52959|Polaribacter	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
DTH2_k127_2212084_1	572479.Hprae_1442	1.047e-80	284.0	COG2989@1|root,COG2989@2|Bacteria,1VU2X@1239|Firmicutes,24Y29@186801|Clostridia,3WBGT@53433|Halanaerobiales	186801|Clostridia	S	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
DTH2_k127_2212084_0	1121904.ARBP01000003_gene6435	1.484e-104	357.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,47K1Y@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
DTH2_k127_2212084_2	266748.HY04_00505	6.234e-20	90.0	COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1I40R@117743|Flavobacteriia	976|Bacteroidetes	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DTH2_k127_2233535_0	1168034.FH5T_16755	3.547e-284	885.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
DTH2_k127_2233535_4	700598.Niako_5254	4.799e-30	124.0	COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
DTH2_k127_2233535_3	313606.M23134_03474	1.947e-112	389.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,47TYP@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
DTH2_k127_2233535_2	269798.CHU_1716	2.472e-133	431.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,47K0S@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH2_k127_2233535_1	869213.JCM21142_41869	4.407e-214	672.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DTH2_k127_22534_0	746697.Aeqsu_1477	2.128e-140	465.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH2_k127_22534_6	1121887.AUDK01000011_gene166	3.261e-26	110.0	2E46C@1|root,32Z2A@2|Bacteria,4NV81@976|Bacteroidetes,1I537@117743|Flavobacteriia,2NXAP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_22534_5	714943.Mucpa_1579	1.355e-37	147.0	2A1N9@1|root,30PWI@2|Bacteria,4NPMN@976|Bacteroidetes,1ISIP@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_22534_3	1408473.JHXO01000013_gene539	5.815e-120	399.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,2FP2A@200643|Bacteroidia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
DTH2_k127_22534_2	1453498.LG45_15500	3.981e-124	412.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1HY8U@117743|Flavobacteriia,2NU0V@237|Flavobacterium	976|Bacteroidetes	EH	Aminobenzoate synthetase	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH2_k127_22534_4	1296416.JACB01000015_gene4713	1.015e-48	181.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia,2YGTV@290174|Aquimarina	976|Bacteroidetes	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
DTH2_k127_22534_1	714943.Mucpa_1530	9.006e-126	409.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1INNA@117747|Sphingobacteriia	976|Bacteroidetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
DTH2_k127_22534_7	1408433.JHXV01000032_gene1121	1.693e-11	70.0	2A9I2@1|root,30YQD@2|Bacteria,4PCM2@976|Bacteroidetes,1IMSU@117743|Flavobacteriia,2PC1C@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2296592_1	1279009.ADICEAN_03646	8.081e-57	214.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DTH2_k127_2296592_3	754476.Q7A_1760	1.975e-07	59.0	COG3431@1|root,COG3431@2|Bacteria,1PP4W@1224|Proteobacteria,1S1QS@1236|Gammaproteobacteria,463HN@72273|Thiotrichales	72273|Thiotrichales	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
DTH2_k127_2296592_2	1506583.JQJY01000010_gene1202	2.076e-21	101.0	COG3685@1|root,COG3685@2|Bacteria,4NMCT@976|Bacteroidetes,1I1BM@117743|Flavobacteriia,2NU53@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
DTH2_k127_2296592_0	1131812.JQMS01000001_gene323	7.331e-185	588.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1I4ES@117743|Flavobacteriia,2NXTG@237|Flavobacterium	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
DTH2_k127_2313633_1	5722.XP_001306110.1	4.211e-10	70.0	COG0666@1|root,KOG4412@2759|Eukaryota	2759|Eukaryota	L	proteasome regulatory particle assembly	-	-	-	ko:K06694	-	-	-	-	ko00000,ko03051	-	-	-	ACBP,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
DTH2_k127_2313633_0	269798.CHU_2223	0.0	1330.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DTH2_k127_2313633_2	1094466.KQS_05340	6.787e-09	58.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,1HYDP@117743|Flavobacteriia,2NSGY@237|Flavobacterium	976|Bacteroidetes	S	membrane	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
DTH2_k127_2315418_0	706587.Desti_4506	1.953e-112	375.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N,ECH_1
DTH2_k127_2315418_3	1047013.AQSP01000139_gene2341	2.86e-07	59.0	COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria	2|Bacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	mocA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3649,iB21_1397.B21_02672,iECABU_c1320.ECABU_c31580,iECBD_1354.ECBD_0860,iECB_1328.ECB_02710,iECD_1391.ECD_02710,iEcHS_1320.EcHS_A3037	HD,HTH_1,NTP_transf_3
DTH2_k127_2315418_2	1347392.CCEZ01000010_gene2411	5.832e-43	168.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,36G5G@31979|Clostridiaceae	186801|Clostridia	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
DTH2_k127_2315418_1	1174504.AJTN02000023_gene4668	4.984e-60	214.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1ZBHS@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG10	-	1.1.1.100,1.3.1.28	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	M00083,M00572	R01505,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00534	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
DTH2_k127_2410848_4	869213.JCM21142_93909	2.593e-152	497.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,47KV8@768503|Cytophagia	976|Bacteroidetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
DTH2_k127_2410848_5	929556.Solca_3233	2.023e-143	462.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,1IP2F@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
DTH2_k127_2410848_13	376686.Fjoh_0648	2.667e-40	156.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia,2NT8G@237|Flavobacterium	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
DTH2_k127_2410848_15	679935.Alfi_0605	2.814e-19	88.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,22UKC@171550|Rikenellaceae	976|Bacteroidetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DTH2_k127_2410848_6	929556.Solca_3252	1.865e-137	443.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DTH2_k127_2410848_3	391596.PBAL39_04748	2.552e-158	505.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_2410848_12	1121931.AUHG01000010_gene335	2.489e-56	200.0	COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1I1AS@117743|Flavobacteriia	976|Bacteroidetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
DTH2_k127_2410848_0	860228.Ccan_02180	9.417e-247	767.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,1HXDC@117743|Flavobacteriia,1EQ6S@1016|Capnocytophaga	976|Bacteroidetes	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH2_k127_2410848_14	929703.KE386491_gene2306	6.362e-25	105.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes,47SE5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
DTH2_k127_2410848_1	1150600.ADIARSV_3081	6.29e-194	612.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,1IPEM@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0826 Collagenase and related	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
DTH2_k127_2410848_11	1121918.ARWE01000001_gene309	2.562e-73	256.0	COG1284@1|root,COG1284@2|Bacteria,1R59F@1224|Proteobacteria,42P6M@68525|delta/epsilon subdivisions,2WKCS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
DTH2_k127_2410848_7	1123248.KB893386_gene1916	2.298e-121	399.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1ISHH@117747|Sphingobacteriia	976|Bacteroidetes	M	SPTR Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
DTH2_k127_2410848_2	929703.KE386491_gene2811	1.068e-192	608.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_2410848_8	929703.KE386491_gene2810	1.276e-104	343.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,47KXC@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH2_k127_2410848_9	694431.DESACE_03590	7.059e-98	328.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
DTH2_k127_2410848_10	468059.AUHA01000007_gene2695	2.844e-76	263.0	2CEQ4@1|root,2ZUK4@2|Bacteria,4NPFT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2410848_16	760192.Halhy_1935	6.144e-15	76.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1IZFK@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH2_k127_24343_5	1408473.JHXO01000010_gene3763	1.476e-82	291.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
DTH2_k127_24343_0	1408433.JHXV01000037_gene2573	1.632e-194	634.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,2PBF0@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_24343_7	153721.MYP_190	1.714e-35	143.0	2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_24343_10	929556.Solca_2962	9.916e-20	98.0	COG3650@1|root,COG3650@2|Bacteria,4NYFH@976|Bacteroidetes,1IUH0@117747|Sphingobacteriia	976|Bacteroidetes	MP	response to hydrogen peroxide	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_24343_2	929556.Solca_1308	5.666e-134	431.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1INUA@117747|Sphingobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_24343_4	755732.Fluta_2685	1.348e-105	367.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_24343_1	1270196.JCKI01000004_gene1152	8.258e-158	502.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1INM8@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylaminoimidazolesuccinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DTH2_k127_24343_3	1270196.JCKI01000004_gene1153	1.767e-127	415.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
DTH2_k127_24343_6	485917.Phep_1862	2.322e-65	231.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IVPQ@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
DTH2_k127_24343_8	504487.JCM19302_3319	4.86e-31	124.0	COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
DTH2_k127_2486599_2	1237149.C900_03393	2.168e-130	423.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DTH2_k127_2486599_1	388413.ALPR1_04538	4.831e-175	558.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,47P2J@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DTH2_k127_2486599_0	709991.Odosp_0296	4.183e-187	599.0	COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,22WPC@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-glucan phosphorylase	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
DTH2_k127_2527671_6	471854.Dfer_3482	9.29e-134	430.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,47JX2@768503|Cytophagia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_2527671_14	391587.KAOT1_21642	1.718e-34	133.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,1I3ZI@117743|Flavobacteriia	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DTH2_k127_2527671_0	762903.Pedsa_1065	1.901e-313	974.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,1INMK@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DTH2_k127_2527671_5	688270.Celal_2236	3.905e-144	461.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,1F8NZ@104264|Cellulophaga	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH2_k127_2527671_9	1042376.AFPK01000024_gene1380	8.153e-99	326.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1HX41@117743|Flavobacteriia,4066W@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DTH2_k127_2527671_1	313606.M23134_07221	2.225e-210	664.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_2527671_7	313606.M23134_07222	3.884e-115	376.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
DTH2_k127_2527671_16	1120951.AUBG01000010_gene1904	1.749e-23	106.0	2C56J@1|root,32YX8@2|Bacteria,4NW78@976|Bacteroidetes,1I4G6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2527671_13	313606.M23134_07226	1.556e-53	195.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,47QH8@768503|Cytophagia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
DTH2_k127_2527671_11	1123057.P872_05315	1.495e-67	236.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2527671_4	926562.Oweho_0231	2.438e-174	559.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1HZJI@117743|Flavobacteriia,2PBE3@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_2527671_2	485918.Cpin_1853	9.202e-200	634.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1IQ55@117747|Sphingobacteriia	976|Bacteroidetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH2_k127_2527671_8	153721.MYP_4250	7.643e-115	374.0	COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,47N90@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	fabG3	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_2527671_3	153721.MYP_4251	7.845e-198	622.0	COG0304@1|root,COG0304@2|Bacteria,4NFBN@976|Bacteroidetes,47N9A@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_2527671_15	153721.MYP_4252	4.888e-32	126.0	COG0236@1|root,COG0236@2|Bacteria,4NV57@976|Bacteroidetes,47SD1@768503|Cytophagia	976|Bacteroidetes	IQ	acyl carrier protein	acpP_2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_2527671_10	153721.MYP_4253	6.389e-96	323.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,47PF5@768503|Cytophagia	976|Bacteroidetes	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
DTH2_k127_2527671_17	1123248.KB893381_gene1007	1.678e-12	72.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
DTH2_k127_2527671_12	1313421.JHBV01000012_gene4088	8.623e-54	194.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,Trp_halogenase
DTH2_k127_2614909_3	755732.Fluta_1500	8.154e-115	389.0	COG3591@1|root,COG3591@2|Bacteria,4NG2K@976|Bacteroidetes,1IKDE@117743|Flavobacteriia,2PBR5@246874|Cryomorphaceae	976|Bacteroidetes	E	Belongs to the peptidase S1B family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin,Trypsin_2
DTH2_k127_2614909_10	926562.Oweho_3485	2.791e-07	63.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,CW_binding_2,DUF11,Laminin_G_3,MAM,PKD
DTH2_k127_2614909_4	1313421.JHBV01000031_gene1344	9.847e-112	381.0	COG0265@1|root,COG3209@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4PKT1@976|Bacteroidetes	976|Bacteroidetes	O	COG3209 Rhs family protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
DTH2_k127_2614909_8	1408473.JHXO01000001_gene2450	3.803e-18	90.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_2614909_5	926562.Oweho_1930	7.152e-100	340.0	COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1I8RP@117743|Flavobacteriia,2PAPE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
DTH2_k127_2614909_0	504472.Slin_5665	0.0	1049.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
DTH2_k127_2614909_1	391587.KAOT1_19677	1.046e-233	729.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia	976|Bacteroidetes	C	Polysulphide reductase	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH2_k127_2614909_6	1239415.CM001837_gene1435	8.693e-55	196.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia,37DQ9@326319|Dokdonia	976|Bacteroidetes	C	Protein of unknown function (DUF3341)	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
DTH2_k127_2614909_7	743722.Sph21_1552	7.24e-41	159.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH2_k127_2614909_2	1408433.JHXV01000014_gene3655	2.701e-124	410.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia,2PAAV@246874|Cryomorphaceae	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2667379_0	525373.HMPREF0766_12595	3.51e-192	623.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQCN@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_2667379_1	1123248.KB893333_gene2789	6.496e-101	347.0	COG3386@1|root,COG5295@1|root,COG3386@2|Bacteria,COG5295@2|Bacteria,4NMCF@976|Bacteroidetes,1IWGC@117747|Sphingobacteriia	2|Bacteria	UW	Domain of unknown function (DUF5122) beta-propeller	yeeJ	-	-	ko:K14274,ko:K20276,ko:K21449	ko00040,ko02024,map00040,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
DTH2_k127_269958_9	755732.Fluta_2398	3.63e-54	203.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_269958_11	1122605.KB893647_gene340	1.164e-40	158.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_16,TPR_8
DTH2_k127_269958_10	700598.Niako_6484	4.625e-42	156.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1IT8P@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
DTH2_k127_269958_7	929556.Solca_4164	8.409e-75	258.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1ISBF@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
DTH2_k127_269958_6	485918.Cpin_0710	1.261e-82	287.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
DTH2_k127_269958_4	1168034.FH5T_09310	8.383e-94	318.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,2FS6N@200643|Bacteroidia	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
DTH2_k127_269958_0	1237149.C900_00016	7.208e-204	641.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
DTH2_k127_269958_1	1086011.HJ01_01192	1.002e-140	454.0	COG1541@1|root,COG1541@2|Bacteria,4PKAN@976|Bacteroidetes,1HX4F@117743|Flavobacteriia,2NSIU@237|Flavobacterium	976|Bacteroidetes	H	acyl transferase	luxE	-	-	-	-	-	-	-	-	-	-	-	LuxE
DTH2_k127_269958_3	1122605.KB893628_gene4483	1.603e-108	371.0	COG0306@1|root,COG0306@2|Bacteria,4NE7J@976|Bacteroidetes,1IPR3@117747|Sphingobacteriia	976|Bacteroidetes	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DTH2_k127_269958_8	468059.AUHA01000002_gene579	5.104e-71	246.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DTH2_k127_269958_5	1341155.FSS13T_14320	2.987e-90	302.0	COG0704@1|root,COG0704@2|Bacteria,4NNT5@976|Bacteroidetes,1I1UU@117743|Flavobacteriia,2NTDB@237|Flavobacterium	976|Bacteroidetes	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
DTH2_k127_269958_2	1107311.Q767_08895	4.044e-134	430.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1HZHC@117743|Flavobacteriia,2NSSM@237|Flavobacterium	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
DTH2_k127_2761624_7	1107311.Q767_04250	1.8e-32	129.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia,2NW2C@237|Flavobacterium	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
DTH2_k127_2761624_3	946077.W5A_00175	5.041e-55	200.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1HXP2@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_2761624_4	1168034.FH5T_16720	3.996e-53	194.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,2G13J@200643|Bacteroidia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH2_k127_2761624_5	1408433.JHXV01000005_gene2270	5.288e-51	195.0	COG3391@1|root,COG3391@2|Bacteria,4PBC0@976|Bacteroidetes,1IMR3@117743|Flavobacteriia,2PBJ5@246874|Cryomorphaceae	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2761624_8	153721.MYP_3676	9.964e-15	81.0	COG0484@1|root,COG0484@2|Bacteria,4PBHX@976|Bacteroidetes,47VX4@768503|Cytophagia	976|Bacteroidetes	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
DTH2_k127_2761624_0	1124780.ANNU01000030_gene1189	3.814e-144	464.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH2_k127_2761624_1	929556.Solca_0293	2.886e-118	396.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2761624_6	1122176.KB903531_gene2819	8.38e-51	187.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2761624_2	553177.CAPSP0001_2196	2.048e-96	318.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia,1EQWZ@1016|Capnocytophaga	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_2882682_3	143224.JQMD01000002_gene4164	1.52e-49	183.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1HXVJ@117743|Flavobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DTH2_k127_2882682_6	1121899.Q764_00855	4.785e-29	121.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1I23F@117743|Flavobacteriia,2NWAX@237|Flavobacterium	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_2882682_7	468059.AUHA01000006_gene3037	4.06e-26	109.0	COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,1ITXA@117747|Sphingobacteriia	976|Bacteroidetes	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
DTH2_k127_2882682_4	1250006.JHZZ01000001_gene2660	7.994e-37	152.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1I0BY@117743|Flavobacteriia,3VVKH@52959|Polaribacter	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
DTH2_k127_2882682_1	929556.Solca_2338	1.1e-55	200.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS97@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
DTH2_k127_2882682_9	714943.Mucpa_4219	2.641e-18	88.0	2E372@1|root,32Y6U@2|Bacteria,4NUUI@976|Bacteroidetes,1IU59@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
DTH2_k127_2882682_0	1185876.BN8_06515	1.293e-56	211.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia	976|Bacteroidetes	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
DTH2_k127_2882682_5	706587.Desti_2788	3.156e-31	136.0	COG0457@1|root,COG0457@2|Bacteria,1RKBA@1224|Proteobacteria	1224|Proteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LprI,Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DTH2_k127_2882682_2	1453498.LG45_06340	5.676e-51	183.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia,2NUAF@237|Flavobacterium	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_2933482_1	1408433.JHXV01000030_gene1398	2.502e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes,1ICNQ@117743|Flavobacteriia,2PBCJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2933482_0	1250006.JHZZ01000001_gene1250	2.601e-124	408.0	COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,1HZ4W@117743|Flavobacteriia,3VVCB@52959|Polaribacter	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH2_k127_301023_2	1408473.JHXO01000009_gene3363	1.182e-102	342.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,2FM75@200643|Bacteroidia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_301023_1	929556.Solca_3378	5.105e-103	343.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
DTH2_k127_301023_3	862965.PARA_02750	2.92e-72	248.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,1YABV@135625|Pasteurellales	135625|Pasteurellales	M	Bacterial sugar transferase	-	-	2.7.8.40	ko:K21303	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf
DTH2_k127_301023_0	1408433.JHXV01000024_gene1493	3.249e-165	528.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,1HZBY@117743|Flavobacteriia,2PBDW@246874|Cryomorphaceae	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_301023_4	1237149.C900_03023	7.86e-21	102.0	COG3307@1|root,COG3307@2|Bacteria,4NUP9@976|Bacteroidetes,47V2J@768503|Cytophagia	976|Bacteroidetes	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_31115_4	880073.Calab_3086	0.000572	52.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_31115_0	580332.Slit_2861	0.0	1465.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
DTH2_k127_31115_2	153721.MYP_951	6.401e-24	111.0	COG0382@1|root,COG0382@2|Bacteria,4P9RC@976|Bacteroidetes,47RXG@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
DTH2_k127_31115_1	929556.Solca_2809	3.962e-77	262.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_3184986_3	762903.Pedsa_2229	1.921e-111	363.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,1IRP1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_3184986_2	592029.DDD_1764	1.955e-118	394.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia,3HKVN@363408|Nonlabens	976|Bacteroidetes	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
DTH2_k127_3184986_1	485917.Phep_3229	3.786e-203	640.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,1IQSD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH2_k127_3184986_6	1121904.ARBP01000003_gene6201	9.075e-53	203.0	COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_3184986_7	1336803.PHEL49_0807	1.437e-37	145.0	2EJEE@1|root,33D5E@2|Bacteria,4NZ5A@976|Bacteroidetes,1IBRH@117743|Flavobacteriia,3VXB7@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3184986_0	762903.Pedsa_3478	3.18e-234	736.0	COG1032@1|root,COG1032@2|Bacteria,4NJAN@976|Bacteroidetes	976|Bacteroidetes	C	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH2_k127_3184986_4	643867.Ftrac_2856	3.632e-92	307.0	COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,47MTQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
DTH2_k127_3201988_3	1313421.JHBV01000024_gene5040	1.487e-195	617.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
DTH2_k127_3201988_21	36874.HQ34_03115	3.617e-27	116.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,22XTD@171551|Porphyromonadaceae	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_3201988_13	1408433.JHXV01000009_gene1287	9.171e-59	209.0	COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes,1IMRD@117743|Flavobacteriia,2PBNX@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH2_k127_3201988_18	760192.Halhy_0079	1.568e-39	166.0	COG2319@1|root,COG2319@2|Bacteria,4NW8I@976|Bacteroidetes	976|Bacteroidetes	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3201988_16	686340.Metal_3843	7.453e-49	193.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,1T460@1236|Gammaproteobacteria,1XEF0@135618|Methylococcales	135618|Methylococcales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3201988_19	1237149.C900_01068	9.402e-37	145.0	COG2067@1|root,COG2067@2|Bacteria,4PMEK@976|Bacteroidetes,47QPW@768503|Cytophagia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3201988_12	865937.Gilli_1632	4.474e-66	232.0	COG0300@1|root,COG0300@2|Bacteria,4NEFB@976|Bacteroidetes,1HX0Q@117743|Flavobacteriia,2P5QT@244698|Gillisia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_3201988_7	925409.KI911562_gene380	4.03e-128	458.0	COG1361@1|root,COG3209@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_3201988_23	391596.PBAL39_20585	2.96e-14	88.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CBM26,CBM_25,CHU_C
DTH2_k127_3201988_15	755732.Fluta_2897	2.45e-57	216.0	COG2885@1|root,COG2885@2|Bacteria,4NUG7@976|Bacteroidetes,1IKE3@117743|Flavobacteriia,2PBU8@246874|Cryomorphaceae	976|Bacteroidetes	M	Pfam:DUF3308	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_3201988_14	1408433.JHXV01000004_gene3458	2.636e-58	223.0	COG4409@1|root,COG4409@2|Bacteria,4PBA1@976|Bacteroidetes,1ICPD@117743|Flavobacteriia,2PBHN@246874|Cryomorphaceae	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3201988_17	1408433.JHXV01000016_gene1862	5.655e-44	169.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia,2PB5B@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH2_k127_3201988_24	1121887.AUDK01000029_gene2534	2.332e-10	67.0	2E7ZI@1|root,30SND@2|Bacteria,4PABN@976|Bacteroidetes,1ID0S@117743|Flavobacteriia,2NWQX@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3201988_5	926562.Oweho_1077	2.907e-187	607.0	COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1HXZU@117743|Flavobacteriia	976|Bacteroidetes	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
DTH2_k127_3201988_4	925409.KI911562_gene2147	1.092e-189	599.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IP5F@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_3201988_11	1144313.PMI10_02118	5.469e-93	312.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia,2NU0D@237|Flavobacterium	976|Bacteroidetes	M	Hydrolase Nlp P60	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
DTH2_k127_3201988_10	929556.Solca_0551	1.078e-114	376.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH2_k127_3201988_9	1408433.JHXV01000012_gene3977	1.821e-121	415.0	COG1404@1|root,COG1404@2|Bacteria,4NTWX@976|Bacteroidetes,1I4GV@117743|Flavobacteriia,2PBAJ@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_3201988_1	1121129.KB903359_gene1052	1.092e-267	833.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FNIS@200643|Bacteroidia,22X8D@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATP-binding cassette protein, ChvD family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
DTH2_k127_3201988_20	56107.Cylst_1452	6.105e-30	129.0	2EPY9@1|root,33HIV@2|Bacteria,1G8GC@1117|Cyanobacteria,1HK47@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3201988_0	929556.Solca_1313	4.9e-269	845.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH2_k127_3201988_6	694427.Palpr_2597	1.596e-181	578.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,2FM6I@200643|Bacteroidia,22X5W@171551|Porphyromonadaceae	976|Bacteroidetes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DTH2_k127_3201988_2	1121889.AUDM01000013_gene1856	3.206e-225	706.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2NSUV@237|Flavobacterium	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH2_k127_3201988_8	746697.Aeqsu_0488	3.461e-123	402.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH2_k127_3251158_3	1408433.JHXV01000009_gene1349	2.163e-105	355.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IMQG@117743|Flavobacteriia,2PBAV@246874|Cryomorphaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
DTH2_k127_3251158_1	1250232.JQNJ01000001_gene3268	4.824e-129	419.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia	976|Bacteroidetes	M	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_3251158_4	1346330.M472_06695	1.314e-73	252.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DTH2_k127_3251158_7	1453498.LG45_04900	2.593e-06	55.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2NU0I@237|Flavobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5
DTH2_k127_3251158_6	1121287.AUMU01000022_gene2647	3.741e-31	137.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1INKJ@117743|Flavobacteriia,3ZRYW@59732|Chryseobacterium	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_3251158_5	762903.Pedsa_2878	5.583e-63	223.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
DTH2_k127_3251158_2	714943.Mucpa_2748	1.483e-112	368.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH2_k127_3251158_0	929556.Solca_4085	1.24e-198	628.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
DTH2_k127_33166_6	760192.Halhy_5568	1.527e-17	91.0	COG2067@1|root,COG2067@2|Bacteria,4PN73@976|Bacteroidetes,1IYCH@117747|Sphingobacteriia	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_33166_3	391598.FBBAL38_11404	2.556e-125	407.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1HZ20@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH2_k127_33166_1	1121896.JMLU01000018_gene2867	1.472e-254	795.0	COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia,2NU1S@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
DTH2_k127_33166_0	1121904.ARBP01000005_gene4654	7.077e-255	797.0	COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,47KS8@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH2_k127_33166_5	1237149.C900_01876	4.832e-59	210.0	COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,47K1H@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM Acetolactate synthase, small subunit	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
DTH2_k127_33166_2	391598.FBBAL38_11424	2.067e-180	569.0	COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,1HYM2@117743|Flavobacteriia	976|Bacteroidetes	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
DTH2_k127_33166_4	926556.Echvi_3354	5.742e-100	331.0	COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47MBE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
DTH2_k127_334388_3	1454007.JAUG01000020_gene1636	1.805e-75	256.0	COG1884@1|root,COG1884@2|Bacteria,4PN0H@976|Bacteroidetes,1IPCT@117747|Sphingobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DTH2_k127_334388_5	153721.MYP_31	2.766e-34	137.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_334388_4	945713.IALB_0164	1.358e-52	190.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
DTH2_k127_334388_7	1121904.ARBP01000002_gene6994	7.707e-08	64.0	COG2849@1|root,COG2849@2|Bacteria,4NSYD@976|Bacteroidetes,47RIN@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_334388_0	1121898.Q766_14610	1.041e-166	532.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1HYA7@117743|Flavobacteriia,2NSGC@237|Flavobacterium	976|Bacteroidetes	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_334388_1	929556.Solca_2092	1.194e-117	387.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
DTH2_k127_334388_2	929703.KE386491_gene341	3.676e-101	334.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DTH2_k127_334388_6	760192.Halhy_6315	9.326e-12	71.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,1ISMS@117747|Sphingobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_3348628_1	313606.M23134_06114	1.731e-46	185.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_3348628_0	1121897.AUGO01000007_gene440	1.459e-90	313.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
DTH2_k127_3357200_11	1123234.AUKI01000010_gene1721	1.3e-19	88.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,1I02M@117743|Flavobacteriia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3357200_12	1121129.KB903364_gene2954	5.776e-10	61.0	2AHEJ@1|root,317RR@2|Bacteria,4P93N@976|Bacteroidetes,2FZC5@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3357200_5	927658.AJUM01000037_gene2418	8.952e-60	229.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,2FNYT@200643|Bacteroidia,3XJ0F@558415|Marinilabiliaceae	976|Bacteroidetes	H	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
DTH2_k127_3357200_2	929556.Solca_2970	9.341e-189	597.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1IPF3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3357200_1	929556.Solca_1913	2.026e-200	636.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DTH2_k127_3357200_8	1121373.KB903665_gene3025	3.115e-39	151.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,47RSF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3357200_10	649349.Lbys_3508	1.165e-24	110.0	COG2353@1|root,COG2353@2|Bacteria,4NT3W@976|Bacteroidetes,47R2B@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_3357200_6	926562.Oweho_1160	7.828e-49	180.0	COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1I376@117743|Flavobacteriia,2PBTV@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DTH2_k127_3357200_3	1286632.P278_32550	2.905e-100	336.0	COG0457@1|root,COG0457@2|Bacteria,4NGID@976|Bacteroidetes,1HX60@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3357200_7	1121904.ARBP01000009_gene4229	6.267e-43	169.0	COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,47WA7@768503|Cytophagia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3357200_4	700598.Niako_2529	3.902e-96	319.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1IS56@117747|Sphingobacteriia	976|Bacteroidetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
DTH2_k127_3357200_14	1333523.L593_02125	7.26e-06	56.0	COG3794@1|root,arCOG02921@2157|Archaea,2XZ0D@28890|Euryarchaeota,23WZS@183963|Halobacteria	183963|Halobacteria	C	COG3794 Plastocyanin	hcp4	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,TAT_signal
DTH2_k127_3357200_9	1348583.ATLH01000001_gene3802	4.164e-28	119.0	COG2207@1|root,COG2207@2|Bacteria,4PDRV@976|Bacteroidetes,1IERC@117743|Flavobacteriia,1FACM@104264|Cellulophaga	976|Bacteroidetes	K	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
DTH2_k127_3357200_0	1237149.C900_05488	0.0	1727.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
DTH2_k127_3436716_3	926562.Oweho_1125	1.825e-23	102.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1HZF4@117743|Flavobacteriia,2PAU5@246874|Cryomorphaceae	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_3436716_2	1120966.AUBU01000003_gene1558	1.368e-34	135.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia	976|Bacteroidetes	J	PFAM translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DTH2_k127_3436716_0	1270196.JCKI01000002_gene59	1.115e-164	526.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_3436716_1	926562.Oweho_1135	2.161e-89	299.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia,2PA7Q@246874|Cryomorphaceae	976|Bacteroidetes	GV	PFAM Glycosyl hydrolase family 3 N terminal domain	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_3462313_0	926562.Oweho_1807	8.722e-205	672.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_3462313_1	1313421.JHBV01000016_gene5520	5.699e-79	269.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,1J079@117747|Sphingobacteriia	976|Bacteroidetes	P	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_3462313_2	493475.GARC_2032	2.585e-20	92.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,468GN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
DTH2_k127_3496376_0	929556.Solca_3964	2.088e-155	511.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,1IQ3M@117747|Sphingobacteriia	976|Bacteroidetes	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_3496376_1	331113.SNE_A07170	4.747e-54	195.0	COG1597@1|root,COG1597@2|Bacteria,2JH3J@204428|Chlamydiae	204428|Chlamydiae	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_3556340_1	153721.MYP_1890	1.161e-155	495.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_3556340_0	1408433.JHXV01000027_gene3728	2.103e-214	703.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_3556340_2	755732.Fluta_1504	5.475e-36	150.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2PC6H@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
DTH2_k127_357398_2	468059.AUHA01000002_gene1060	3.846e-90	302.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1IQ1N@117747|Sphingobacteriia	976|Bacteroidetes	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
DTH2_k127_357398_3	28115.HR11_08725	2.878e-68	236.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,2FQY1@200643|Bacteroidia,22XUD@171551|Porphyromonadaceae	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
DTH2_k127_357398_1	1313421.JHBV01000043_gene3030	1.697e-101	336.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1INQT@117747|Sphingobacteriia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
DTH2_k127_357398_0	485918.Cpin_1862	5.79e-148	477.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IUWM@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
DTH2_k127_3587975_4	1121011.AUCB01000004_gene2825	2.356e-28	116.0	COG1730@1|root,COG1730@2|Bacteria,4NHZT@976|Bacteroidetes,1HZM3@117743|Flavobacteriia,23GBX@178469|Arenibacter	976|Bacteroidetes	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH2_k127_3587975_5	926556.Echvi_4121	1.19e-18	91.0	COG0723@1|root,COG0723@2|Bacteria,4NJPJ@976|Bacteroidetes	976|Bacteroidetes	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
DTH2_k127_3587975_2	755732.Fluta_3942	7.379e-54	198.0	COG2197@1|root,COG2197@2|Bacteria,4NNVV@976|Bacteroidetes,1ICPE@117743|Flavobacteriia,2PBHR@246874|Cryomorphaceae	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
DTH2_k127_3587975_1	1237149.C900_04769	9.404e-102	340.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,47KGX@768503|Cytophagia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
DTH2_k127_3587975_6	1408433.JHXV01000019_gene1974	5.511e-09	66.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	3.2.1.51,4.2.2.23	ko:K10297,ko:K15923,ko:K18197	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04121	-	GH95,PL11	-	Beta_helix,CBM_35,Glyco_hydro_98M
DTH2_k127_3587975_3	385682.AFSL01000003_gene1919	1.255e-33	132.0	COG1366@1|root,COG1366@2|Bacteria,4NTAB@976|Bacteroidetes,2FYPE@200643|Bacteroidia,3XK5M@558415|Marinilabiliaceae	976|Bacteroidetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
DTH2_k127_3587975_0	762903.Pedsa_1915	5.507e-129	414.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH2_k127_360109_4	1270193.JARP01000001_gene2626	3.027e-104	347.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia,2NSQ9@237|Flavobacterium	976|Bacteroidetes	C	Acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH2_k127_360109_9	1123037.AUDE01000032_gene2266	2.859e-62	215.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1IJ7N@117743|Flavobacteriia	976|Bacteroidetes	C	ferredoxin	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
DTH2_k127_360109_11	714943.Mucpa_4965	3.817e-56	208.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_360109_1	1453500.AT05_00910	5.325e-160	511.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
DTH2_k127_360109_12	1408813.AYMG01000028_gene2555	1.072e-48	180.0	COG0431@1|root,COG0431@2|Bacteria,4NQV9@976|Bacteroidetes,1IRZM@117747|Sphingobacteriia	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH2_k127_360109_7	1123248.KB893337_gene2339	1.699e-93	311.0	COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
DTH2_k127_360109_2	391596.PBAL39_23928	3.498e-130	420.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1IQ5V@117747|Sphingobacteriia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DTH2_k127_360109_6	1408433.JHXV01000010_gene615	1.682e-97	329.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia,2PAB0@246874|Cryomorphaceae	976|Bacteroidetes	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DTH2_k127_360109_14	385682.AFSL01000023_gene2128	3.094e-36	145.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,2FTY0@200643|Bacteroidia,3XK1I@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_360109_8	1408813.AYMG01000028_gene2551	3.934e-91	306.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
DTH2_k127_360109_3	1123035.ARLA01000027_gene362	6.955e-120	406.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1HY4X@117743|Flavobacteriia,4C347@83612|Psychroflexus	976|Bacteroidetes	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH2_k127_360109_5	742817.HMPREF9449_00747	5.256e-102	342.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,2FNMS@200643|Bacteroidia,22W4M@171551|Porphyromonadaceae	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH2_k127_360109_10	763034.HMPREF9446_00595	1.206e-58	209.0	COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,2FNPU@200643|Bacteroidia,4AKF5@815|Bacteroidaceae	976|Bacteroidetes	C	WbqC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
DTH2_k127_360109_0	1121898.Q766_06305	3.245e-290	897.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia,2NU4U@237|Flavobacterium	976|Bacteroidetes	I	Methylcrotonoyl-CoA carboxylase	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
DTH2_k127_360109_13	945713.IALB_2304	9.777e-37	145.0	2CBKC@1|root,32RTJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_360109_15	720554.Clocl_1029	7.57e-22	95.0	COG3021@1|root,COG3021@2|Bacteria,1UKTK@1239|Firmicutes,25G3G@186801|Clostridia,3WNK8@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846,Exo_endo_phos
DTH2_k127_3604576_19	1434325.AZQN01000001_gene338	1.01e-81	278.0	COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,47N85@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
DTH2_k127_3604576_32	926562.Oweho_0417	1.078e-19	91.0	COG2921@1|root,COG2921@2|Bacteria,4PA5G@976|Bacteroidetes,1IGIZ@117743|Flavobacteriia,2PB80@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
DTH2_k127_3604576_33	1226325.HMPREF1548_00019	6.124e-16	79.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,36MKH@31979|Clostridiaceae	186801|Clostridia	S	S4 domain protein	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
DTH2_k127_3604576_24	1094466.KQS_03855	1.865e-51	186.0	COG4319@1|root,COG4319@2|Bacteria,4NS10@976|Bacteroidetes,1II83@117743|Flavobacteriia,2NWG5@237|Flavobacterium	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
DTH2_k127_3604576_1	929562.Emtol_2167	1.641e-171	564.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47K4Y@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
DTH2_k127_3604576_2	1237149.C900_00478	8.325e-164	520.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,47K90@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH2_k127_3604576_26	641526.ADIWIN_2598	1.041e-36	152.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_3604576_8	655815.ZPR_1880	1.29e-134	441.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia	976|Bacteroidetes	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
DTH2_k127_3604576_11	485918.Cpin_5452	1.291e-112	367.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1IPJX@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
DTH2_k127_3604576_4	1408433.JHXV01000004_gene3405	1.86e-152	490.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,2PBBH@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
DTH2_k127_3604576_6	1380384.JADN01000003_gene530	2.275e-136	447.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3604576_17	1408433.JHXV01000005_gene2292	4.279e-86	293.0	COG2746@1|root,COG2746@2|Bacteria,4NWN7@976|Bacteroidetes,1I525@117743|Flavobacteriia,2PBE1@246874|Cryomorphaceae	976|Bacteroidetes	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
DTH2_k127_3604576_14	1469557.JSWF01000028_gene2926	7.164e-93	315.0	COG0726@1|root,COG0726@2|Bacteria,4NQKC@976|Bacteroidetes,1I8X4@117743|Flavobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3604576_23	1408473.JHXO01000010_gene3653	1.583e-54	202.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,2FT4P@200643|Bacteroidia	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
DTH2_k127_3604576_16	755732.Fluta_2237	6.436e-90	300.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,1HX32@117743|Flavobacteriia,2PBNQ@246874|Cryomorphaceae	976|Bacteroidetes	F	Uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
DTH2_k127_3604576_35	1168034.FH5T_10120	5.661e-08	60.0	2EVWW@1|root,33PAJ@2|Bacteria,4NZKD@976|Bacteroidetes,2FZQQ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3604576_22	643867.Ftrac_1841	6.408e-62	221.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,47Q1Q@768503|Cytophagia	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
DTH2_k127_3604576_18	525373.HMPREF0766_11919	6.243e-86	289.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1INZC@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DTH2_k127_3604576_3	1408473.JHXO01000008_gene2784	1.405e-157	519.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
DTH2_k127_3604576_36	1519464.HY22_05630	1.324e-06	58.0	2BQJ0@1|root,32XXI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
DTH2_k127_3604576_27	1121889.AUDM01000003_gene2304	3.095e-35	138.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia,2NWMV@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DTH2_k127_3604576_13	391596.PBAL39_08821	3.598e-96	331.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,1INNI@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_3604576_10	153721.MYP_2118	6.296e-114	400.0	COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971
DTH2_k127_3604576_9	1408433.JHXV01000013_gene2586	5.167e-124	413.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia,2PAKB@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH2_k127_3604576_7	391603.FBALC1_02112	4.983e-135	439.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1HWJX@117743|Flavobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH2_k127_3604576_12	1317122.ATO12_07860	1.382e-97	324.0	COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,1HWQP@117743|Flavobacteriia,2YH8K@290174|Aquimarina	976|Bacteroidetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
DTH2_k127_3604576_31	1168289.AJKI01000002_gene2694	9.654e-29	132.0	28NPZ@1|root,2ZBPQ@2|Bacteria,4NN3K@976|Bacteroidetes,2FPEH@200643|Bacteroidia,3XJXJ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_3604576_21	313595.P700755_001752	9.513e-67	238.0	COG2304@1|root,COG2304@2|Bacteria,4NKZ6@976|Bacteroidetes,1IFZZ@117743|Flavobacteriia,4C41B@83612|Psychroflexus	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_3604576_34	880071.Fleli_3027	1.065e-15	94.0	2DM4Q@1|root,31Q2U@2|Bacteria,4NINP@976|Bacteroidetes,47R63@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3604576_0	649349.Lbys_0384	0.0	1430.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_3604576_20	1408433.JHXV01000015_gene1745	1.038e-74	262.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Antigen_C,DUF4150,PorP_SprF
DTH2_k127_3604576_28	153721.MYP_2754	3.856e-35	146.0	28PY8@1|root,2ZCHZ@2|Bacteria,4NMGG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3604576_25	1123277.KB893179_gene3096	2.794e-45	169.0	COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,47PSM@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
DTH2_k127_3604576_5	1358423.N180_12205	2.307e-138	450.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DTH2_k127_3604576_30	1123057.P872_24670	9.575e-29	116.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,47RA0@768503|Cytophagia	976|Bacteroidetes	O	NifU domain protein	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
DTH2_k127_3604576_15	153721.MYP_4007	8.044e-93	320.0	COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,47NWX@768503|Cytophagia	976|Bacteroidetes	E	GDSL family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
DTH2_k127_3604576_29	1120966.AUBU01000018_gene247	6.774e-35	135.0	COG3177@1|root,COG3177@2|Bacteria,4NF0H@976|Bacteroidetes,47JUU@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
DTH2_k127_3666296_0	1408433.JHXV01000018_gene3848	2.339e-240	779.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I7ZV@117743|Flavobacteriia,2PAMN@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_3666296_1	1313421.JHBV01000005_gene4510	3.221e-30	124.0	COG2067@1|root,COG2067@2|Bacteria,4PN73@976|Bacteroidetes,1IYCH@117747|Sphingobacteriia	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_3702679_17	1313265.JNIE01000003_gene1401	5.187e-21	100.0	COG2862@1|root,COG2862@2|Bacteria	2|Bacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
DTH2_k127_3702679_21	468059.AUHA01000003_gene2021	1.104e-06	50.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IPXM@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Resolvase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH2_k127_3702679_4	761193.Runsl_5254	3.65e-144	464.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
DTH2_k127_3702679_5	471854.Dfer_5317	1.136e-138	451.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
DTH2_k127_3702679_13	1131812.JQMS01000001_gene2073	2.466e-39	150.0	2AXFQ@1|root,31PF8@2|Bacteria,4NQN3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3702679_3	762903.Pedsa_0375	4.517e-191	605.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1IPSZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH2_k127_3702679_10	487796.Flav2ADRAFT_0749	5.025e-51	184.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,1I173@117743|Flavobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_3702679_7	1168034.FH5T_09735	4.29e-65	230.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes	976|Bacteroidetes	S	cytochrome c biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
DTH2_k127_3702679_14	929556.Solca_1395	3.734e-30	125.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
DTH2_k127_3702679_2	929556.Solca_1394	6.396e-196	620.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
DTH2_k127_3702679_6	700598.Niako_1943	3.128e-76	270.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
DTH2_k127_3702679_19	929556.Solca_1392	2.195e-11	65.0	COG2010@1|root,COG2010@2|Bacteria,4PJ6S@976|Bacteroidetes,1IZP1@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3702679_0	929556.Solca_1391	0.0	1184.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
DTH2_k127_3702679_18	1450525.JATV01000006_gene926	1.445e-13	71.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia,2NXI9@237|Flavobacterium	976|Bacteroidetes	P	cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
DTH2_k127_3702679_1	929556.Solca_1389	5.866e-265	838.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_3702679_11	1123248.KB893386_gene1913	1.29e-46	178.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1IU5A@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0589 Universal stress protein UspA and related nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_3702679_15	1237149.C900_03377	1.4e-26	115.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,47P55@768503|Cytophagia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
DTH2_k127_3702679_12	931276.Cspa_c18170	6.413e-41	154.0	COG0346@1|root,COG0346@2|Bacteria,1VY90@1239|Firmicutes,24Q48@186801|Clostridia,36S4Z@31979|Clostridiaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3702679_16	697282.Mettu_4065	9.184e-25	107.0	2E373@1|root,32ZYW@2|Bacteria,1P98F@1224|Proteobacteria,1SW8T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3702679_8	1270196.JCKI01000005_gene3133	6.029e-63	219.0	COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes	976|Bacteroidetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DTH2_k127_3702679_9	1408473.JHXO01000008_gene2782	1.556e-55	201.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
DTH2_k127_3729928_1	1189612.A33Q_2156	6.477e-177	561.0	COG2223@1|root,COG2223@2|Bacteria,4NJ57@976|Bacteroidetes,47TAZ@768503|Cytophagia	976|Bacteroidetes	P	Transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,MgtE_N
DTH2_k127_3729928_0	296591.Bpro_3273	4.883e-202	644.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,4AAPE@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Major facilitator superfamily	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
DTH2_k127_3817817_0	755732.Fluta_0944	3.457e-167	546.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2PAM4@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
DTH2_k127_3817817_4	1124780.ANNU01000005_gene2433	1.973e-57	210.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,47NE3@768503|Cytophagia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
DTH2_k127_3817817_2	929556.Solca_3261	1.659e-104	355.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1IQB4@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
DTH2_k127_3817817_1	1408813.AYMG01000015_gene5047	2.994e-155	494.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1INQ9@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_3817817_7	1168289.AJKI01000004_gene2954	5.151e-39	150.0	2DRX2@1|root,33DGD@2|Bacteria,4NY6I@976|Bacteroidetes,2FVFY@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3817817_5	391596.PBAL39_20575	2.997e-45	188.0	COG5295@1|root,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
DTH2_k127_3817817_3	398720.MED217_15260	4.939e-66	254.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH2_k127_3817817_8	1392488.JHZY01000002_gene365	8.398e-06	59.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4NN7P@976|Bacteroidetes,1I1GH@117743|Flavobacteriia,2XJCX@283735|Leeuwenhoekiella	976|Bacteroidetes	UW	Head domain of trimeric autotransporter adhesin	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	YadA_head
DTH2_k127_3817817_9	1107311.Q767_15455	3.569e-05	49.0	COG4886@1|root,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia,2NT0J@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_3818997_0	1408433.JHXV01000038_gene2198	1.907e-80	296.0	COG2885@1|root,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_3818997_4	886379.AEWI01000055_gene2633	3.375e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,4NHH0@976|Bacteroidetes,2FP90@200643|Bacteroidia,3XJJE@558415|Marinilabiliaceae	976|Bacteroidetes	S	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_16
DTH2_k127_3818997_3	1307759.JOMJ01000003_gene1949	2.592e-09	69.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X672@28221|Deltaproteobacteria,2MGXM@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Thrombospondin type 3 repeat	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
DTH2_k127_3818997_1	1313421.JHBV01000022_gene4705	1.843e-16	92.0	COG1196@1|root,COG2885@1|root,COG1196@2|Bacteria,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_3818997_2	598659.NAMH_0418	1.407e-12	77.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2YT3M@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Thrombospondin type 3 repeat	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
DTH2_k127_3921667_0	1122621.ATZA01000002_gene1607	1.112e-189	595.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,1IQZ1@117747|Sphingobacteriia	976|Bacteroidetes	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DTH2_k127_3921667_3	1173263.Syn7502_03070	2.227e-99	331.0	COG1682@1|root,COG1682@2|Bacteria,1G23R@1117|Cyanobacteria,1GZUH@1129|Synechococcus	1117|Cyanobacteria	U	transport, permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
DTH2_k127_3921667_1	32057.KB217478_gene1814	2.382e-125	413.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1HMN9@1161|Nostocales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
DTH2_k127_3921667_5	598659.NAMH_1665	3.379e-51	196.0	COG0438@1|root,COG0438@2|Bacteria,1N5XR@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH2_k127_3921667_4	1120965.AUBV01000009_gene3058	1.075e-79	273.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
DTH2_k127_3921667_2	376686.Fjoh_0326	1.908e-117	388.0	COG0438@1|root,COG0438@2|Bacteria,4NJXJ@976|Bacteroidetes,1IIRQ@117743|Flavobacteriia,2NVGC@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_3925820_3	886379.AEWI01000046_gene3091	5.172e-91	303.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,2FNAK@200643|Bacteroidia,3XJ5Z@558415|Marinilabiliaceae	976|Bacteroidetes	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DTH2_k127_3925820_4	1296415.JACC01000039_gene4000	6.297e-86	291.0	2CHAC@1|root,2Z7QK@2|Bacteria,4NKKS@976|Bacteroidetes,1HXFF@117743|Flavobacteriia,2YIVJ@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3925820_1	1237149.C900_00992	3.315e-158	512.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH2_k127_3925820_0	1124780.ANNU01000006_gene2819	6.677e-214	681.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_3925820_2	755732.Fluta_2055	1.43e-127	419.0	COG0438@1|root,COG0438@2|Bacteria,4PI5K@976|Bacteroidetes,1IGDT@117743|Flavobacteriia,2PB9M@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_3925820_5	1408433.JHXV01000044_gene3183	2.804e-61	218.0	COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,1ICQF@117743|Flavobacteriia,2PBRF@246874|Cryomorphaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
DTH2_k127_3940470_23	1313421.JHBV01000042_gene3231	1.041e-24	109.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1ISIT@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_3940470_10	755732.Fluta_3173	4.96e-111	408.0	COG0419@1|root,COG1196@1|root,COG3391@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,COG3391@2|Bacteria,4PP0U@976|Bacteroidetes,1ICPT@117743|Flavobacteriia,2PBJT@246874|Cryomorphaceae	976|Bacteroidetes	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3940470_26	1121896.JMLU01000010_gene1431	0.0003285	55.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia,2NSP4@237|Flavobacterium	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH2_k127_3940470_21	755732.Fluta_3174	1.626e-31	125.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia,2PB69@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATP-dependent Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
DTH2_k127_3940470_11	880073.Calab_0995	3.026e-101	336.0	COG0501@1|root,COG0501@2|Bacteria,2NS4G@2323|unclassified Bacteria	2|Bacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH2_k127_3940470_19	938709.AUSH02000016_gene680	7.635e-40	153.0	COG2050@1|root,COG2050@2|Bacteria,4NNXM@976|Bacteroidetes	976|Bacteroidetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
DTH2_k127_3940470_2	929703.KE386491_gene3153	1.236e-183	578.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47NRC@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_3940470_5	929556.Solca_0026	2.524e-160	507.0	COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1INTX@117747|Sphingobacteriia	976|Bacteroidetes	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_3940470_4	929556.Solca_0029	4.581e-163	530.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
DTH2_k127_3940470_12	1408473.JHXO01000013_gene528	3.045e-98	329.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,2FP92@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
DTH2_k127_3940470_6	1137281.D778_00917	4.36e-154	496.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DTH2_k127_3940470_20	483215.BACFIN_06562	1.889e-39	149.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,2FTC9@200643|Bacteroidia,4AQY4@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG14434 non supervised orthologous group	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
DTH2_k127_3940470_15	762903.Pedsa_0349	5.007e-69	244.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
DTH2_k127_3940470_1	929556.Solca_2733	1.709e-191	606.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1IQY7@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_3940470_22	929556.Solca_0668	3.117e-25	105.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1ITTJ@117747|Sphingobacteriia	976|Bacteroidetes	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DTH2_k127_3940470_13	1506583.JQJY01000001_gene785	2.935e-83	282.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,1HX3G@117743|Flavobacteriia,2NSGW@237|Flavobacterium	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
DTH2_k127_3940470_9	880074.BARVI_00475	8.111e-120	397.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,22VYG@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
DTH2_k127_3940470_8	709991.Odosp_1789	3.503e-126	410.0	COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,22WZN@171551|Porphyromonadaceae	976|Bacteroidetes	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH2_k127_3940470_17	1380384.JADN01000004_gene1728	3.553e-51	183.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
DTH2_k127_3940470_24	1356852.N008_18405	3.41e-21	94.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,47RYG@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
DTH2_k127_3940470_14	435591.BDI_0661	1.153e-71	248.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,2FNF1@200643|Bacteroidia,22X5B@171551|Porphyromonadaceae	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DTH2_k127_3940470_0	468059.AUHA01000005_gene2555	0.0	1104.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
DTH2_k127_3940470_25	1408433.JHXV01000001_gene1044	1.137e-11	71.0	2AB69@1|root,310KH@2|Bacteria,4PF6A@976|Bacteroidetes,1IFSI@117743|Flavobacteriia,2PC3T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3940470_18	1408433.JHXV01000001_gene1045	2.499e-46	178.0	29N3N@1|root,30P01@2|Bacteria,4PGRH@976|Bacteroidetes,1ICQD@117743|Flavobacteriia,2PBQR@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3940470_7	929556.Solca_0932	3.198e-127	419.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,1IRB4@117747|Sphingobacteriia	976|Bacteroidetes	F	Dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH2_k127_3940470_3	929556.Solca_0931	5.436e-167	548.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
DTH2_k127_3940470_16	1121887.AUDK01000007_gene1728	2.192e-59	213.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,1HY17@117743|Flavobacteriia,2NTKT@237|Flavobacterium	976|Bacteroidetes	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
DTH2_k127_3940520_1	929556.Solca_2251	1.757e-135	443.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
DTH2_k127_3940520_5	755732.Fluta_2145	4.943e-19	88.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0019222,GO:0044464,GO:0048518,GO:0050789,GO:0060255,GO:0065007,GO:0071944	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
DTH2_k127_3940520_3	1349785.BAUG01000011_gene887	6.945e-104	347.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia	976|Bacteroidetes	P	K transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
DTH2_k127_3940520_2	762903.Pedsa_2343	3.558e-110	364.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose reductase	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DTH2_k127_3940520_0	755732.Fluta_1325	7.15e-147	488.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_3940520_4	313606.M23134_02936	2.824e-84	302.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,HAMP,SpoIIE,TPR_12,TPR_8,Y_Y_Y,dCache_1
DTH2_k127_3979883_4	694427.Palpr_2229	9.959e-12	67.0	COG0671@1|root,COG0671@2|Bacteria,4NPUG@976|Bacteroidetes,2FSUS@200643|Bacteroidia,22YR5@171551|Porphyromonadaceae	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DTH2_k127_3979883_3	1380600.AUYN01000007_gene3399	4.117e-16	87.0	28PMD@1|root,2ZCAE@2|Bacteria,4NMHE@976|Bacteroidetes,1I1F0@117743|Flavobacteriia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_3979883_2	1270196.JCKI01000009_gene3378	3.102e-50	186.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes	976|Bacteroidetes	S	IA, variant 3	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH2_k127_3979883_1	313606.M23134_06977	2.061e-61	213.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DTH2_k127_3979883_0	755732.Fluta_1295	7.881e-86	291.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,1IMQI@117743|Flavobacteriia,2PBDZ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_400696_9	1313301.AUGC01000006_gene126	2.281e-72	260.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_400696_3	468059.AUHA01000002_gene793	3.967e-157	502.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_400696_8	1168289.AJKI01000011_gene602	2.052e-78	283.0	2CMNP@1|root,32SF6@2|Bacteria,4NSZE@976|Bacteroidetes,2G31M@200643|Bacteroidia,3XIU2@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_400696_6	1121373.KB903632_gene593	2.047e-101	335.0	COG0463@1|root,COG0463@2|Bacteria,4P0JN@976|Bacteroidetes,47UGH@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_400696_13	706587.Desti_2066	1.85e-34	151.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_400696_10	755732.Fluta_0716	2.889e-60	225.0	COG1835@1|root,COG1835@2|Bacteria,4PIH2@976|Bacteroidetes,1IGD6@117743|Flavobacteriia,2PBU2@246874|Cryomorphaceae	2|Bacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_400696_11	1123037.AUDE01000032_gene2267	1.032e-55	196.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
DTH2_k127_400696_0	1123037.AUDE01000032_gene2265	5.871e-290	893.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia	976|Bacteroidetes	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_400696_4	1123037.AUDE01000032_gene2264	2.559e-133	427.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,1HWTU@117743|Flavobacteriia	976|Bacteroidetes	O	Part of SUF system involved in inserting iron-sulfur clusters into proteins	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
DTH2_k127_400696_2	1123037.AUDE01000032_gene2263	2.363e-161	518.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,1HXNA@117743|Flavobacteriia	976|Bacteroidetes	O	assembly protein, SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_400696_7	926559.JoomaDRAFT_2213	1.221e-83	286.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_400696_14	926562.Oweho_3265	1.822e-23	113.0	COG3291@1|root,COG3291@2|Bacteria,4NU74@976|Bacteroidetes,1I4JY@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_400696_1	643867.Ftrac_0021	1.322e-276	865.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
DTH2_k127_400696_12	1313421.JHBV01000014_gene3816	1.147e-48	186.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4NRAB@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calycin_like,PCMD
DTH2_k127_400696_5	755732.Fluta_1488	5.058e-112	375.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_4021758_14	1116472.MGMO_109c00050	7.458e-10	59.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XE5B@135618|Methylococcales	1236|Gammaproteobacteria	E	PFAM Aminotransferase, class I	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_4021758_4	485918.Cpin_1023	2.241e-97	324.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1INZJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
DTH2_k127_4021758_7	926551.KB900735_gene1530	2.136e-77	278.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,1EQCP@1016|Capnocytophaga	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DTH2_k127_4021758_15	1216967.L100_00305	0.0001958	47.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,34R3E@308865|Elizabethkingia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DTH2_k127_4021758_8	1124780.ANNU01000005_gene2447	1.427e-63	221.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
DTH2_k127_4021758_6	929556.Solca_4334	2.6e-86	296.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
DTH2_k127_4021758_10	1408433.JHXV01000020_gene3501	5.922e-27	122.0	COG4372@1|root,COG4372@2|Bacteria,4PKE4@976|Bacteroidetes,1IKDW@117743|Flavobacteriia,2PBQB@246874|Cryomorphaceae	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4021758_0	743722.Sph21_2470	1.453e-165	526.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1IR3Y@117747|Sphingobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
DTH2_k127_4021758_1	1353276.JADR01000007_gene1479	2.213e-151	483.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1HWPH@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
DTH2_k127_4021758_13	504472.Slin_5074	2.005e-10	63.0	2A7GX@1|root,30WEH@2|Bacteria,4P9UT@976|Bacteroidetes,47S3Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4021758_5	1150600.ADIARSV_0975	7.374e-92	304.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DTH2_k127_4021758_12	1216967.L100_04966	1.565e-11	72.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,34PVP@308865|Elizabethkingia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
DTH2_k127_4021758_11	1453500.AT05_05495	3.265e-26	119.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
DTH2_k127_4021758_2	1453500.AT05_00420	9.874e-137	453.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4021758_9	926562.Oweho_1917	5.815e-57	203.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,1I33N@117743|Flavobacteriia,2PAUY@246874|Cryomorphaceae	976|Bacteroidetes	CO	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_4021758_3	755732.Fluta_1833	2.527e-99	342.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	AhpC-TSA,Omp28
DTH2_k127_4035068_1	153721.MYP_2602	1.571e-77	285.0	COG1572@1|root,COG2931@1|root,COG3227@1|root,COG3266@1|root,COG3291@1|root,COG4447@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_4035068_5	1121904.ARBP01000003_gene6125	3.537e-06	60.0	COG2374@1|root,COG3386@1|root,COG2374@2|Bacteria,COG3386@2|Bacteria,4NHFV@976|Bacteroidetes,47M74@768503|Cytophagia	976|Bacteroidetes	M	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Exo_endo_phos
DTH2_k127_4035068_2	740709.A10D4_00975	9.07e-44	177.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
DTH2_k127_4035068_3	1239962.C943_01476	9.536e-14	82.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,47KMB@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_4035068_4	865938.Weevi_0392	2.977e-08	59.0	2E82Z@1|root,332GZ@2|Bacteria,4NVRZ@976|Bacteroidetes,1I5FX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4035068_0	1450525.JATV01000005_gene387	7.156e-90	305.0	COG1216@1|root,COG1216@2|Bacteria,4NJSE@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_4068037_10	742766.HMPREF9455_02777	4.754e-05	45.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,2FNB6@200643|Bacteroidia,22XHX@171551|Porphyromonadaceae	976|Bacteroidetes	P	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_4068037_5	1237149.C900_01610	3.394e-43	165.0	COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,47XYJ@768503|Cytophagia	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
DTH2_k127_4068037_1	143224.JQMD01000002_gene4268	4.257e-153	512.0	COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1HZB4@117743|Flavobacteriia	976|Bacteroidetes	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
DTH2_k127_4068037_4	746697.Aeqsu_0327	2.095e-62	230.0	28JIH@1|root,2Z9BT@2|Bacteria,4NIF7@976|Bacteroidetes,1HYCU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
DTH2_k127_4068037_6	1173029.JH980292_gene3625	6.09e-24	106.0	COG0745@1|root,COG0745@2|Bacteria,1G5HD@1117|Cyanobacteria,1HBA7@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Response_reg
DTH2_k127_4068037_7	760192.Halhy_0683	1.809e-08	67.0	COG0457@1|root,COG0457@2|Bacteria,4NNMV@976|Bacteroidetes	976|Bacteroidetes	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4068037_8	1408813.AYMG01000033_gene5247	3.203e-07	51.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IPXM@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Resolvase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH2_k127_4068037_0	714943.Mucpa_2062	1.448e-214	687.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPEH@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_4068037_3	1218108.KB908293_gene1141	1.161e-68	248.0	COG0438@1|root,COG0438@2|Bacteria,4PI54@976|Bacteroidetes,1I2FR@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_4068037_2	1408433.JHXV01000012_gene3883	7.994e-84	287.0	COG4122@1|root,COG4122@2|Bacteria,4NPJQ@976|Bacteroidetes,1I85I@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
DTH2_k127_4068037_9	746697.Aeqsu_1344	1.831e-06	61.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1I06M@117743|Flavobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_S8
DTH2_k127_4096626_0	153721.MYP_2567	3.814e-310	971.0	COG1643@1|root,COG1643@2|Bacteria,4NFJ7@976|Bacteroidetes,47KRZ@768503|Cytophagia	976|Bacteroidetes	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
DTH2_k127_4096626_4	1191523.MROS_1246	4.725e-187	596.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_4096626_3	1191523.MROS_1247	4.082e-205	659.0	COG0612@1|root,COG2834@1|root,COG0612@2|Bacteria,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_4096626_9	1408433.JHXV01000010_gene584	6.245e-50	184.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia,2PBNV@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_4096626_6	1408433.JHXV01000001_gene1084	5.792e-101	340.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_4096626_2	742766.HMPREF9455_02762	5.542e-258	803.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia,22WCA@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DTH2_k127_4096626_10	1123278.KB893610_gene4516	4.353e-11	69.0	2DR38@1|root,339ZC@2|Bacteria,4NY0S@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4096626_8	1270196.JCKI01000003_gene2095	3.485e-50	198.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia	976|Bacteroidetes	UW	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
DTH2_k127_4096626_11	1392488.JHZY01000002_gene365	4.027e-09	69.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4NN7P@976|Bacteroidetes,1I1GH@117743|Flavobacteriia,2XJCX@283735|Leeuwenhoekiella	976|Bacteroidetes	UW	Head domain of trimeric autotransporter adhesin	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	YadA_head
DTH2_k127_4096626_7	1121904.ARBP01000004_gene767	2.414e-77	263.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
DTH2_k127_4096626_5	1233950.IW22_13990	9.143e-176	554.0	COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,1HXA5@117743|Flavobacteriia	976|Bacteroidetes	F	reductase	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
DTH2_k127_4096626_1	743722.Sph21_0339	1.307e-280	868.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IQCA@117747|Sphingobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_4272164_3	1121481.AUAS01000007_gene1061	6.652e-11	73.0	COG5305@1|root,COG5305@2|Bacteria,4NHT8@976|Bacteroidetes,47MIS@768503|Cytophagia	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_4272164_1	163908.KB235896_gene4227	2.571e-47	192.0	2C2MB@1|root,340JY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4272164_0	269798.CHU_3003	3.223e-114	372.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47KDC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_4272164_2	755732.Fluta_1341	7.858e-24	117.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IMQ5@117743|Flavobacteriia,2PB6F@246874|Cryomorphaceae	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4343960_5	742726.HMPREF9448_01618	5.475e-20	92.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22XN2@171551|Porphyromonadaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH2_k127_4343960_3	755732.Fluta_0510	3.897e-94	343.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_4343960_4	700598.Niako_4477	4.282e-67	231.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1IRXF@117747|Sphingobacteriia	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
DTH2_k127_4343960_0	869213.JCM21142_72829	1.453e-218	690.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,47JWD@768503|Cytophagia	976|Bacteroidetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DTH2_k127_4343960_1	929556.Solca_0791	1.806e-202	638.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_4343960_6	929556.Solca_1316	1.144e-11	75.0	COG3637@1|root,COG3637@2|Bacteria,4NN1G@976|Bacteroidetes,1J0N8@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_4343960_2	1313421.JHBV01000030_gene2256	3.137e-97	333.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia	976|Bacteroidetes	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DTH2_k127_4356867_0	1270196.JCKI01000003_gene2099	5.862e-220	702.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_4356867_1	869213.JCM21142_72624	0.0003855	43.0	COG1835@1|root,COG1835@2|Bacteria,4NJVW@976|Bacteroidetes	976|Bacteroidetes	I	Acyltransferase family	oatA	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_4360645_1	1168034.FH5T_18330	3.241e-48	192.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4360645_3	1210884.HG799462_gene7865	3.084e-06	59.0	2DSAR@1|root,33F9F@2|Bacteria,2J1A0@203682|Planctomycetes	1210884.HG799462_gene7865|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4360645_2	867900.Celly_0904	1.101e-08	64.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,1F9P2@104264|Cellulophaga	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_4360645_0	313606.M23134_00354	3.025e-62	222.0	2DBB3@1|root,2Z85F@2|Bacteria,4NKCY@976|Bacteroidetes,47PNW@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
DTH2_k127_4372330_0	509635.N824_02835	3.637e-199	624.0	COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DTH2_k127_4372330_1	926562.Oweho_2197	9.89e-183	604.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_4372330_4	620914.JH621252_gene2492	7.272e-88	294.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia,2YGSX@290174|Aquimarina	976|Bacteroidetes	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
DTH2_k127_4372330_5	1122176.KB903560_gene3543	1.305e-76	277.0	28N7K@1|root,2ZBC9@2|Bacteria,4NHU8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
DTH2_k127_4372330_2	153721.MYP_2233	9.181e-149	476.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,47KQ7@768503|Cytophagia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
DTH2_k127_4372330_3	714943.Mucpa_0211	1.044e-128	413.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1IQMU@117747|Sphingobacteriia	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH2_k127_4374653_7	1223410.KN050846_gene666	5.051e-36	151.0	COG1807@1|root,COG1807@2|Bacteria,4PP20@976|Bacteroidetes,1IKN3@117743|Flavobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_4374653_10	1408433.JHXV01000001_gene1086	3.38e-17	95.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4374653_4	880071.Fleli_2045	1.139e-67	239.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DTH2_k127_4374653_8	468059.AUHA01000003_gene1431	1.236e-31	124.0	COG1828@1|root,COG1828@2|Bacteria,4NV1M@976|Bacteroidetes,1ITNI@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DTH2_k127_4374653_5	1107311.Q767_04475	1.128e-65	234.0	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia,2NYK8@237|Flavobacterium	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
DTH2_k127_4374653_1	153721.MYP_4404	2.363e-120	391.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
DTH2_k127_4374653_0	1408473.JHXO01000011_gene3214	4.299e-192	627.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,2FMTK@200643|Bacteroidia	976|Bacteroidetes	M	COG NOG06397 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_4374653_6	1168289.AJKI01000011_gene387	2.289e-54	192.0	COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,2FTME@200643|Bacteroidia,3XK9V@558415|Marinilabiliaceae	976|Bacteroidetes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DTH2_k127_4374653_2	762903.Pedsa_3310	5.126e-82	281.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1INR5@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DTH2_k127_4374653_9	1317122.ATO12_18140	2.992e-22	106.0	COG0457@1|root,COG1287@1|root,COG0457@2|Bacteria,COG1287@2|Bacteria,4PNYV@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT,TPR_19,TPR_8
DTH2_k127_4374653_3	1086011.HJ01_03085	1.246e-69	247.0	COG1835@1|root,COG1835@2|Bacteria,4NJVW@976|Bacteroidetes,1IIRZ@117743|Flavobacteriia	976|Bacteroidetes	I	Acyltransferase family	oatA	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_4434197_5	1121007.AUML01000019_gene768	4.493e-24	104.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1I1RZ@117743|Flavobacteriia,2YJ1Z@290174|Aquimarina	976|Bacteroidetes	IQ	3-oxoacyl-(ACP) synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4434197_0	153721.MYP_4262	2.544e-124	409.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,47PEB@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_4434197_3	1237149.C900_02919	4.025e-43	162.0	COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,47R9P@768503|Cytophagia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_4434197_1	746697.Aeqsu_0926	1.278e-95	328.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia	976|Bacteroidetes	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_4434197_2	1197477.IA57_04620	1.215e-88	299.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_4434197_4	153721.MYP_4256	4.492e-35	138.0	COG0764@1|root,COG0764@2|Bacteria,4PKBK@976|Bacteroidetes,47RZR@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4437913_3	1168034.FH5T_14025	1.427e-32	130.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,2FV8A@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_4437913_0	880071.Fleli_1561	8.187e-228	721.0	COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia	976|Bacteroidetes	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_4437913_2	1168289.AJKI01000012_gene322	1.216e-93	319.0	COG0438@1|root,COG0438@2|Bacteria,4NMHA@976|Bacteroidetes,2FTK8@200643|Bacteroidia,3XK9W@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH2_k127_4437913_1	880071.Fleli_3574	6.481e-98	323.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
DTH2_k127_4455136_7	1450525.JATV01000012_gene3062	5.131e-21	94.0	COG1180@1|root,COG1180@2|Bacteria,4NM78@976|Bacteroidetes,1I8ZG@117743|Flavobacteriia,2NV2F@237|Flavobacterium	976|Bacteroidetes	O	anaerobic ribonucleoside-triphosphate reductase activating protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DTH2_k127_4455136_9	32024.JMTI01000016_gene389	6.171e-19	87.0	COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,42V5U@68525|delta/epsilon subdivisions,2YQAB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	-	-	-	-	-	-	-	-	-	-	NRDD
DTH2_k127_4455136_0	1341181.FLJC2902T_05960	0.0	1197.0	COG1328@1|root,COG1328@2|Bacteria,4NGPS@976|Bacteroidetes,1IIZS@117743|Flavobacteriia,2NTDY@237|Flavobacterium	976|Bacteroidetes	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
DTH2_k127_4455136_5	1286632.P278_09270	6.791e-46	169.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1I2ZX@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH2_k127_4455136_1	1150600.ADIARSV_0356	9.209e-120	392.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,4NE9M@976|Bacteroidetes,1IS5X@117747|Sphingobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
DTH2_k127_4455136_4	1123248.KB893326_gene1352	6.095e-46	176.0	COG4309@1|root,COG4309@2|Bacteria,4NR74@976|Bacteroidetes,1IT66@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
DTH2_k127_4455136_3	266748.HY04_04635	5.226e-74	264.0	COG3278@1|root,COG3278@2|Bacteria,4NGGE@976|Bacteroidetes,1IH7Q@117743|Flavobacteriia,3ZT9J@59732|Chryseobacterium	976|Bacteroidetes	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4455136_8	1550091.JROE01000002_gene581	5.12e-19	90.0	COG2151@1|root,COG2151@2|Bacteria,4NV07@976|Bacteroidetes,1IU0N@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH2_k127_4455136_6	555500.I215_02193	2.414e-36	142.0	COG1959@1|root,COG1959@2|Bacteria,4NPHI@976|Bacteroidetes,1I2QC@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH2_k127_4455136_2	153721.MYP_1454	3.105e-98	327.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,47K22@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
DTH2_k127_4522250_2	1270196.JCKI01000008_gene1468	4.078e-52	186.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
DTH2_k127_4522250_1	616991.JPOO01000001_gene3276	6.288e-55	198.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia,23G0Q@178469|Arenibacter	976|Bacteroidetes	L	RuvA, C-terminal domain	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DTH2_k127_4522250_0	1408473.JHXO01000001_gene2295	0.0	1560.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
DTH2_k127_4524091_4	929556.Solca_3852	1.638e-73	250.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,1IQPX@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_4524091_5	755732.Fluta_0875	2.414e-58	209.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia,2PAXI@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
DTH2_k127_4524091_2	1408433.JHXV01000009_gene1333	8.905e-109	383.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,4NSXT@976|Bacteroidetes,1I7KG@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_4524091_0	1408433.JHXV01000009_gene1334	9.51e-185	615.0	COG3291@1|root,COG3291@2|Bacteria,4PI0I@976|Bacteroidetes,1I5WG@117743|Flavobacteriia,2PBH4@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_4524091_3	1408433.JHXV01000009_gene1335	8.859e-97	327.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
DTH2_k127_4524091_1	755732.Fluta_3108	2.605e-153	508.0	COG1729@1|root,COG2885@1|root,COG1729@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2PBBP@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_4585056_0	485918.Cpin_6850	1.175e-142	461.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,1IPV9@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
DTH2_k127_4585056_1	153721.MYP_4254	3.707e-72	254.0	COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,47PXR@768503|Cytophagia	976|Bacteroidetes	C	Dialkylrecorsinol condensing enzyme DarA	darA	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4585056_2	269798.CHU_2789	7.972e-35	143.0	2CFX6@1|root,32S2Q@2|Bacteria,4NTW8@976|Bacteroidetes,47VJ9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4585056_3	153721.MYP_897	1.256e-20	96.0	2CFX6@1|root,32S2Q@2|Bacteria,4NTW8@976|Bacteroidetes,47VJ9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4650839_5	929556.Solca_3015	4.674e-85	284.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1IPX4@117747|Sphingobacteriia	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DTH2_k127_4650839_16	929556.Solca_3014	2.269e-33	130.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,1ISRK@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DTH2_k127_4650839_10	1150600.ADIARSV_3615	7.289e-61	212.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1IS0B@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DTH2_k127_4650839_7	485917.Phep_0617	2.422e-78	265.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DTH2_k127_4650839_14	1223410.KN050846_gene1284	1.902e-43	161.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
DTH2_k127_4650839_6	929556.Solca_3010	4.695e-84	282.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1IQ9B@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DTH2_k127_4650839_17	755732.Fluta_0761	2.767e-15	77.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1I55H@117743|Flavobacteriia,2PB6D@246874|Cryomorphaceae	976|Bacteroidetes	J	TIGRFAM ribosomal protein L30, bacterial organelle	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
DTH2_k127_4650839_13	525373.HMPREF0766_10442	6.162e-58	204.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1IRSX@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DTH2_k127_4650839_0	886379.AEWI01000002_gene534	4.383e-192	608.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia,3XISD@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecY translocase	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DTH2_k127_4650839_3	929556.Solca_3006	5.08e-120	390.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,1IP59@117747|Sphingobacteriia	976|Bacteroidetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DTH2_k127_4650839_15	927658.AJUM01000040_gene862	1.566e-38	144.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,2FTSU@200643|Bacteroidia,3XKBU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Translation initiation factor 1A / IF-1	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH2_k127_4650839_18	926562.Oweho_3081	6.627e-14	71.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia,2PC34@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
DTH2_k127_4650839_11	1122621.ATZA01000014_gene3232	9.885e-60	208.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DTH2_k127_4650839_9	1227272.HMPREF1556_01521	8.778e-62	214.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,2FRZD@200643|Bacteroidia,22XN9@171551|Porphyromonadaceae	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DTH2_k127_4650839_4	509635.N824_07250	2.162e-89	298.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DTH2_k127_4650839_1	755732.Fluta_0753	4.892e-171	541.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia,2PA8U@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DTH2_k127_4650839_12	926549.KI421517_gene236	1.064e-59	211.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,47PPE@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
DTH2_k127_4650839_2	468059.AUHA01000002_gene1386	3.584e-162	518.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,1IPSN@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH2_k127_4650839_8	761193.Runsl_0898	1.362e-73	259.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM Bacteroidetes-specific	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_4724980_1	485917.Phep_3748	4.079e-136	451.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1INME@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_4724980_2	1123037.AUDE01000032_gene2256	6.108e-62	215.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
DTH2_k127_4724980_0	1150600.ADIARSV_2467	0.0	1173.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_4724980_3	929556.Solca_3504	5.422e-61	213.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,1ISDN@117747|Sphingobacteriia	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
DTH2_k127_4766468_5	926562.Oweho_2422	3.423e-116	377.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
DTH2_k127_4766468_1	1408433.JHXV01000006_gene2788	5.835e-252	811.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_4766468_9	1121904.ARBP01000005_gene4844	4.846e-72	257.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47N2D@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
DTH2_k127_4766468_2	926562.Oweho_3509	7.38e-199	630.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,1I8AX@117743|Flavobacteriia,2PAB3@246874|Cryomorphaceae	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
DTH2_k127_4766468_10	1122176.KB903535_gene1970	9.321e-64	236.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
DTH2_k127_4766468_4	755732.Fluta_2847	1.204e-120	392.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia,2PA74@246874|Cryomorphaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_4766468_6	1189619.pgond44_11476	1.691e-91	313.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1HWU8@117743|Flavobacteriia,4C308@83612|Psychroflexus	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
DTH2_k127_4766468_3	509635.N824_11305	6.331e-152	488.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,1IP4G@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
DTH2_k127_4766468_7	927658.AJUM01000034_gene116	2.653e-86	293.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,3XIQ9@558415|Marinilabiliaceae	976|Bacteroidetes	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
DTH2_k127_4766468_8	926549.KI421517_gene831	6.089e-86	302.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,47K28@768503|Cytophagia	976|Bacteroidetes	I	PFAM Outer membrane protein transport protein (OMPP1 FadL TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
DTH2_k127_4766468_14	984262.SGRA_2747	4.471e-15	88.0	2BZQ4@1|root,32TE6@2|Bacteria,4NTHT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4766468_0	714943.Mucpa_5383	2.128e-265	824.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1IQ4M@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DTH2_k127_4766468_11	742725.HMPREF9450_01118	3.085e-58	210.0	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,2FXHA@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4766468_12	509635.N824_06610	7.21e-26	108.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1IYFW@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
DTH2_k127_4873898_2	211165.AJLN01000047_gene6187	1.839e-78	267.0	COG0259@1|root,COG0259@2|Bacteria,1G0HC@1117|Cyanobacteria,1JHDR@1189|Stigonemataceae	1117|Cyanobacteria	H	Pfam:PNPOx_C	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.pdxH	PNP_phzG_C,Putative_PNPOx
DTH2_k127_4873898_3	743722.Sph21_3549	3.598e-77	267.0	COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH2_k127_4873898_5	436114.SYO3AOP1_0223	3.512e-42	161.0	COG0241@1|root,COG0241@2|Bacteria,2G469@200783|Aquificae	200783|Aquificae	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
DTH2_k127_4873898_4	1313421.JHBV01000005_gene4580	1.121e-56	204.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1IS8Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_4873898_0	929703.KE386491_gene2330	2.851e-168	538.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH2_k127_4873898_1	153721.MYP_3101	4.282e-89	313.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4P298@976|Bacteroidetes,47TIX@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_4888245_2	706587.Desti_1813	2.42e-60	212.0	COG2080@1|root,COG2080@2|Bacteria,1RE5X@1224|Proteobacteria	1224|Proteobacteria	C	(2Fe-2S) binding domain protein	-	-	1.2.5.3,1.3.99.8	ko:K03518,ko:K16879	ko00365,ko01120,map00365,map01120	-	R02987,R11168	RC01856,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
DTH2_k127_4888245_1	706587.Desti_1814	8.614e-70	246.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42RE0@68525|delta/epsilon subdivisions,2WNYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein	pcmR	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
DTH2_k127_4888245_0	706587.Desti_1815	7.642e-141	454.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MR87@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DTH2_k127_4932772_2	927658.AJUM01000037_gene2297	4.955e-139	469.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,2G0DG@200643|Bacteroidia,3XJHT@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_4932772_3	927658.AJUM01000037_gene2298	8.001e-111	367.0	COG3291@1|root,COG3291@2|Bacteria,4NHJJ@976|Bacteroidetes,2G20Y@200643|Bacteroidia,3XJ8K@558415|Marinilabiliaceae	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4932772_4	266748.HY04_10325	1.919e-66	241.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1I0XW@117743|Flavobacteriia,3ZP0H@59732|Chryseobacterium	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
DTH2_k127_4932772_5	880071.Fleli_2828	4.475e-55	198.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,47Q72@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_4932772_1	927658.AJUM01000017_gene3127	1.162e-157	506.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia,3XJRR@558415|Marinilabiliaceae	976|Bacteroidetes	L	helicase superfamily c-terminal domain	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
DTH2_k127_4932772_7	746697.Aeqsu_3202	4.198e-42	164.0	COG0526@1|root,COG0526@2|Bacteria,4NZHV@976|Bacteroidetes,1IAZB@117743|Flavobacteriia	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH2_k127_4932772_0	929556.Solca_1745	1.079e-265	826.0	COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,1IP6T@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
DTH2_k127_4932772_6	1121104.AQXH01000001_gene1459	3.505e-53	201.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH2_k127_4974817_1	1279009.ADICEAN_01757	1e-35	139.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,47K61@768503|Cytophagia	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_4974817_0	929556.Solca_3148	3.824e-142	457.0	COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1J0C0@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
DTH2_k127_4974817_2	1121875.KB907550_gene694	0.000215	44.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DTH2_k127_4989542_0	1237149.C900_03252	7.414e-182	575.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,47JQE@768503|Cytophagia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
DTH2_k127_4989542_7	929556.Solca_3905	8.018e-45	165.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1ISQ9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DTH2_k127_4989542_4	1121889.AUDM01000019_gene89	1.149e-108	355.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,1HXFN@117743|Flavobacteriia,2NSVS@237|Flavobacterium	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DTH2_k127_4989542_2	1408813.AYMG01000019_gene1814	8.487e-161	511.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,1IPD7@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
DTH2_k127_4989542_3	485918.Cpin_2998	6.814e-116	385.0	COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,1IRHF@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_4989542_6	504472.Slin_5562	4.465e-64	225.0	COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,47Q2B@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
DTH2_k127_4989542_1	504472.Slin_5888	9.562e-175	557.0	COG0161@1|root,COG0161@2|Bacteria,4NEJN@976|Bacteroidetes,47KV0@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,BATS,Radical_SAM
DTH2_k127_4989542_5	1270193.JARP01000002_gene1087	1.332e-97	323.0	COG1738@1|root,COG1738@2|Bacteria,4NNPU@976|Bacteroidetes,1I2GG@117743|Flavobacteriia,2NU67@237|Flavobacterium	976|Bacteroidetes	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
DTH2_k127_5012307_1	927658.AJUM01000022_gene997	1.262e-84	296.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,2G3HG@200643|Bacteroidia,3XJX6@558415|Marinilabiliaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
DTH2_k127_5012307_0	555500.I215_12763	1.046e-204	643.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DTH2_k127_5012307_2	880070.Cycma_2852	1.612e-13	73.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes,47R73@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
DTH2_k127_5082652_23	700598.Niako_4479	7.388e-24	108.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_5082652_10	755732.Fluta_0695	2.766e-116	398.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4P0PU@976|Bacteroidetes,1IMQT@117743|Flavobacteriia,2PBGH@246874|Cryomorphaceae	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5082652_7	926562.Oweho_2308	2.906e-142	468.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBM8@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_5082652_9	386456.JQKN01000001_gene1666	5.628e-121	432.0	COG0784@1|root,COG3920@1|root,arCOG02348@1|root,arCOG02352@1|root,arCOG02335@2157|Archaea,arCOG02348@2157|Archaea,arCOG02352@2157|Archaea,arCOG06537@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH2_k127_5082652_11	1408433.JHXV01000015_gene1712	7.79e-111	362.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia,2PAUQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH2_k127_5082652_0	1408473.JHXO01000001_gene2164	2.406e-270	853.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,2FMM6@200643|Bacteroidia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
DTH2_k127_5082652_19	1408433.JHXV01000015_gene1717	1.894e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia,2PAZ5@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_5082652_24	1410608.JNKX01000025_gene533	2.272e-18	96.0	COG3291@1|root,COG3291@2|Bacteria,4NU2U@976|Bacteroidetes,2FNZM@200643|Bacteroidia,4APYD@815|Bacteroidaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_5082652_15	755732.Fluta_2090	6.253e-72	274.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_5082652_13	517418.Ctha_1807	1.425e-74	259.0	COG1864@1|root,COG1864@2|Bacteria,1FFIK@1090|Chlorobi	1090|Chlorobi	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
DTH2_k127_5082652_25	760192.Halhy_1797	2.726e-05	49.0	COG4244@1|root,COG4244@2|Bacteria,4NRDG@976|Bacteroidetes,1IT23@117747|Sphingobacteriia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5082652_18	1484460.JSWG01000009_gene275	1.732e-60	222.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
DTH2_k127_5082652_3	1237149.C900_00716	6.985e-198	625.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
DTH2_k127_5082652_4	926562.Oweho_2105	7.914e-184	637.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia,2PC60@246874|Cryomorphaceae	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_5082652_26	1453498.LG45_06900	4.55e-05	58.0	COG1361@1|root,COG2373@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,4NJEG@976|Bacteroidetes,1HZDT@117743|Flavobacteriia,2P056@237|Flavobacterium	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_5082652_16	1121373.KB903621_gene1721	1.654e-70	274.0	COG5184@1|root,COG5184@2|Bacteria,4NQ1Y@976|Bacteroidetes	2|Bacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,CHU_C,DUF3494,RCC1,RCC1_2
DTH2_k127_5082652_27	1341181.FLJC2902T_10840	0.0007086	54.0	COG4733@1|root,COG4935@1|root,COG4733@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,2NU0I@237|Flavobacterium	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
DTH2_k127_5082652_22	1185876.BN8_06294	2.5e-45	168.0	COG0838@1|root,COG0838@2|Bacteria,4NQJB@976|Bacteroidetes,47Q47@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH2_k127_5082652_12	1346330.M472_22010	2.177e-94	311.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1INQ8@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH2_k127_5082652_20	153721.MYP_738	6.342e-55	197.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,47PAN@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH2_k127_5082652_2	153721.MYP_737	9.301e-212	662.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,47KBK@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DTH2_k127_5082652_17	1218103.CIN01S_13_00670	3.127e-67	233.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1HZPI@117743|Flavobacteriia,3ZQR9@59732|Chryseobacterium	976|Bacteroidetes	C	NADH-quinone oxidoreductase subunit E	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
DTH2_k127_5082652_1	1408813.AYMG01000036_gene3284	8.123e-236	734.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
DTH2_k127_5082652_6	1270196.JCKI01000001_gene3977	4.07e-154	492.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes	976|Bacteroidetes	C	NADH dehydrogenase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
DTH2_k127_5082652_8	1341181.FLJC2902T_10300	5.208e-136	439.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,1I435@117743|Flavobacteriia,2NU8A@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_5082652_5	269798.CHU_1375	4.102e-156	499.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47K9J@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH2_k127_5082652_14	755732.Fluta_1965	2.246e-73	252.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
DTH2_k127_5082652_21	1454007.JAUG01000007_gene2148	7.439e-51	185.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH2_k127_5105628_6	929556.Solca_2965	1.018e-20	96.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_5105628_1	1168034.FH5T_01850	2.771e-71	248.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,2FQ12@200643|Bacteroidia	976|Bacteroidetes	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
DTH2_k127_5105628_7	1346330.M472_21550	8.127e-07	56.0	2E5TM@1|root,330HY@2|Bacteria,4NVEY@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5105628_5	1121373.KB903644_gene3389	1.514e-26	121.0	COG0526@1|root,COG0526@2|Bacteria,4PIJM@976|Bacteroidetes	976|Bacteroidetes	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5105628_3	1123248.KB893314_gene3434	1.372e-53	198.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,1IQMF@117747|Sphingobacteriia	976|Bacteroidetes	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
DTH2_k127_5105628_2	886379.AEWI01000046_gene3109	5.83e-55	196.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia,3XK37@558415|Marinilabiliaceae	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
DTH2_k127_5105628_4	700598.Niako_5142	2.775e-39	154.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH2_k127_5105628_0	926562.Oweho_0646	1.211e-78	268.0	COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,1HX8U@117743|Flavobacteriia,2PAJ8@246874|Cryomorphaceae	976|Bacteroidetes	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
DTH2_k127_5124093_1	1416760.AYMS01000046_gene2736	6.808e-70	243.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1HXC6@117743|Flavobacteriia,47H31@76831|Myroides	976|Bacteroidetes	V	LD-carboxypeptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
DTH2_k127_5124093_2	755732.Fluta_0073	1.715e-22	100.0	COG2346@1|root,COG2346@2|Bacteria,4NVGJ@976|Bacteroidetes,1I53B@117743|Flavobacteriia	976|Bacteroidetes	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
DTH2_k127_5124093_0	926549.KI421517_gene2601	1.273e-264	819.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,47JB3@768503|Cytophagia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DTH2_k127_5195474_6	1408433.JHXV01000010_gene583	8.157e-15	91.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	2.1.1.72,3.1.4.46,3.2.1.1	ko:K00571,ko:K01126,ko:K01176	ko00500,ko00564,ko01100,ko04973,map00500,map00564,map01100,map04973	-	R01030,R01470,R02108,R02112,R11262	RC00017,RC00425	ko00000,ko00001,ko01000,ko02048	-	GH13	-	CHU_C,PKD
DTH2_k127_5195474_1	929556.Solca_2664	8.42e-279	927.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_5195474_5	926562.Oweho_0948	4.334e-22	115.0	COG2132@1|root,COG4412@1|root,COG2132@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	ina	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,Peptidase_M6
DTH2_k127_5195474_0	1121904.ARBP01000006_gene4059	0.0	1486.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47N7Y@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
DTH2_k127_5195474_3	1121035.AUCH01000002_gene1569	2.248e-81	295.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,2KUNX@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,Response_reg
DTH2_k127_5195474_4	391625.PPSIR1_30631	6.57e-46	188.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	3.1.3.16	ko:K06382,ko:K07013	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,SpoIIE,V4R
DTH2_k127_5195474_2	760192.Halhy_0104	4.696e-191	601.0	COG1914@1|root,COG1914@2|Bacteria,4NDZ1@976|Bacteroidetes,1IQNY@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
DTH2_k127_5206934_2	755732.Fluta_0823	1.797e-23	100.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia,2PAVX@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
DTH2_k127_5206934_1	929703.KE386491_gene1174	2.021e-34	144.0	COG0589@1|root,COG0589@2|Bacteria,4NP07@976|Bacteroidetes,47Q13@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_5206934_0	926562.Oweho_1286	1.863e-49	188.0	COG0589@1|root,COG0589@2|Bacteria,4PICR@976|Bacteroidetes,1I8WQ@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_5235738_0	1454007.JAUG01000085_gene3264	5.7e-268	837.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes	976|Bacteroidetes	E	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH2_k127_5235738_5	926549.KI421517_gene3725	5.924e-28	119.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5235738_2	1453500.AT05_09010	5.551e-148	473.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
DTH2_k127_5235738_4	1185876.BN8_06352	8.168e-95	318.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH2_k127_5235738_3	1408473.JHXO01000006_gene1066	8.743e-123	403.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_5235738_1	762903.Pedsa_1842	1.985e-206	646.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1INNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DTH2_k127_524701_1	1408433.JHXV01000001_gene1086	1.534e-30	136.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_524701_0	714943.Mucpa_2069	0.0	1149.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
DTH2_k127_524701_2	565034.BHWA1_02529	1.385e-28	124.0	COG0457@1|root,COG0457@2|Bacteria,2JAA8@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8
DTH2_k127_524701_4	1121373.KB903625_gene3189	3.362e-22	103.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_524701_3	1121373.KB903620_gene2241	7.595e-24	110.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,47P6I@768503|Cytophagia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_5287711_8	1408433.JHXV01000028_gene2156	9.45e-09	62.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_5287711_5	1137281.D778_00456	1.082e-31	129.0	295MU@1|root,2ZSZ8@2|Bacteria,4NP18@976|Bacteroidetes,1I1YU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5287711_2	709797.CSIRO_2713	2.972e-192	608.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,3JSXW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_5287711_6	1250006.JHZZ01000001_gene811	4.916e-30	127.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	DUF4367,TonB_C
DTH2_k127_5287711_4	153721.MYP_4845	5.964e-33	129.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,47V8W@768503|Cytophagia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_5287711_1	583355.Caka_1220	6.22e-220	710.0	COG0457@1|root,COG3379@1|root,COG3551@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,COG3551@2|Bacteria,46URB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH2_k127_5287711_11	1237149.C900_05552	8.611e-05	53.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,47TYM@768503|Cytophagia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_5287711_3	700598.Niako_0938	1.087e-112	371.0	COG3000@1|root,COG3000@2|Bacteria,4NI60@976|Bacteroidetes,1IQSK@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DTH2_k127_5287711_0	485918.Cpin_0164	4.627e-295	924.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,1IP6N@117747|Sphingobacteriia	976|Bacteroidetes	M	Penicillin-binding Protein	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
DTH2_k127_5287711_12	755732.Fluta_1290	9.716e-05	53.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
DTH2_k127_5287711_10	153721.MYP_4659	3.837e-06	53.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,47RWM@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
DTH2_k127_5287711_9	1150600.ADIARSV_2471	1.045e-08	59.0	COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,1INQ5@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH2_k127_5299827_2	1250005.PHEL85_0577	7.623e-24	108.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5299827_0	1484460.JSWG01000015_gene1027	4.929e-132	458.0	COG2866@1|root,COG3291@1|root,COG2866@2|Bacteria,COG3291@2|Bacteria,4NH4I@976|Bacteroidetes,1I15Z@117743|Flavobacteriia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DTH2_k127_5299827_1	1150600.ADIARSV_0356	6.435e-103	342.0	COG2846@1|root,COG4309@1|root,COG2846@2|Bacteria,COG4309@2|Bacteria,4NE9M@976|Bacteroidetes,1IS5X@117747|Sphingobacteriia	976|Bacteroidetes	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin,ScdA_N
DTH2_k127_5309733_2	1185876.BN8_06697	5.433e-98	343.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_5309733_1	929556.Solca_2750	4.823e-143	460.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IQAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_5309733_3	929562.Emtol_1436	3.159e-63	222.0	COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,47QB7@768503|Cytophagia	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
DTH2_k127_5309733_0	485917.Phep_0513	1.994e-144	463.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
DTH2_k127_5309733_5	926562.Oweho_1024	2.694e-32	136.0	28MPU@1|root,2ZAYW@2|Bacteria,4PJIE@976|Bacteroidetes,1I9N3@117743|Flavobacteriia,2PC5G@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5309733_4	385682.AFSL01000014_gene2755	4.732e-47	172.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,2FTDR@200643|Bacteroidia,3XK62@558415|Marinilabiliaceae	976|Bacteroidetes	O	OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
DTH2_k127_5309733_6	926562.Oweho_1025	3.551e-28	117.0	COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1I47G@117743|Flavobacteriia,2PB66@246874|Cryomorphaceae	976|Bacteroidetes	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
DTH2_k127_531456_5	926549.KI421517_gene3701	4.328e-59	217.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
DTH2_k127_531456_1	153721.MYP_2625	1.32e-204	655.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
DTH2_k127_531456_8	386456.JQKN01000015_gene2930	3.533e-23	102.0	COG0784@1|root,arCOG06537@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH2_k127_531456_3	103690.17131330	7.311e-68	251.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3290@1|root,COG3920@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG3920@2|Bacteria,1GPYK@1117|Cyanobacteria,1HUCG@1161|Nostocales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_2,PAS,PAS_3,PAS_9,Response_reg
DTH2_k127_531456_9	743974.MBO_05434	7.822e-21	96.0	COG5263@1|root,COG5263@2|Bacteria,1RJ7C@1224|Proteobacteria,1S9E6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_531456_0	1416760.AYMS01000060_gene2181	0.0	1527.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1INDD@117743|Flavobacteriia,47IN6@76831|Myroides	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
DTH2_k127_531456_2	755732.Fluta_1284	1.222e-81	289.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_531456_10	1168289.AJKI01000025_gene1465	2.041e-14	78.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes,2G27E@200643|Bacteroidia,3XK8F@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_531456_7	886379.AEWI01000049_gene3206	1.306e-45	176.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,2G223@200643|Bacteroidia,3XJ24@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_531456_11	1189612.A33Q_4467	9.485e-12	69.0	2E3I4@1|root,32YGK@2|Bacteria,4NUQ9@976|Bacteroidetes,47S6Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_531456_4	714943.Mucpa_3953	3.292e-60	213.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1ISQD@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF420)	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
DTH2_k127_531456_6	860228.Ccan_02690	2.715e-52	192.0	COG1999@1|root,COG1999@2|Bacteria,4NGHC@976|Bacteroidetes,1HXW6@117743|Flavobacteriia,1EQYJ@1016|Capnocytophaga	976|Bacteroidetes	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_5321144_3	1008457.BAEX01000056_gene685	6.458e-10	60.0	2DRFB@1|root,33BGM@2|Bacteria,4NXIN@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5321144_1	1121957.ATVL01000010_gene399	3.209e-135	443.0	COG0477@1|root,COG0477@2|Bacteria,4PKN6@976|Bacteroidetes,47XX9@768503|Cytophagia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_5321144_2	1356852.N008_17565	1.665e-43	162.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DTH2_k127_5321144_0	929556.Solca_0531	1.601e-151	485.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_5375841_9	1408473.JHXO01000001_gene2009	1.964e-13	74.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,2FPZX@200643|Bacteroidia	976|Bacteroidetes	KT	PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
DTH2_k127_5375841_11	908612.HMPREF9720_0808	1.078e-06	59.0	2EHJH@1|root,33BBD@2|Bacteria,4PMZ1@976|Bacteroidetes,2G0M1@200643|Bacteroidia,22VM1@171550|Rikenellaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5375841_0	1380384.JADN01000006_gene2464	0.0	1075.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_5375841_6	313590.MED134_11881	5.373e-116	379.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia,37DVI@326319|Dokdonia	976|Bacteroidetes	G	SIS domain	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
DTH2_k127_5375841_7	755732.Fluta_0615	2.939e-88	294.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IMPU@117743|Flavobacteriia,2PATN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5375841_1	468059.AUHA01000002_gene1351	3.437e-282	874.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IQEH@117747|Sphingobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
DTH2_k127_5375841_3	1408433.JHXV01000008_gene153	7.101e-196	631.0	COG3291@1|root,COG4188@1|root,COG3291@2|Bacteria,COG4188@2|Bacteria,4NKC2@976|Bacteroidetes,1HZ4A@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
DTH2_k127_5375841_8	760192.Halhy_5518	3.238e-32	128.0	2E3V1@1|root,32YSA@2|Bacteria,4NV88@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5375841_5	926562.Oweho_0378	1.442e-143	478.0	COG2885@1|root,COG3063@1|root,COG2885@2|Bacteria,COG3063@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PA4T@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
DTH2_k127_5375841_2	929556.Solca_0511	8.172e-210	684.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IRAR@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
DTH2_k127_5375841_4	641526.ADIWIN_3762	6.497e-162	516.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,1HYC0@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DTH2_k127_5375841_10	592029.DDD_2343	6.241e-07	59.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,3HKXH@363408|Nonlabens	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5
DTH2_k127_5384699_4	1123008.KB905695_gene2740	5.435e-17	86.0	COG0671@1|root,COG0671@2|Bacteria,4NPUG@976|Bacteroidetes,2FSUS@200643|Bacteroidia,22YR5@171551|Porphyromonadaceae	976|Bacteroidetes	I	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DTH2_k127_5384699_1	755732.Fluta_1775	8.925e-173	555.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia,2PAMH@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
DTH2_k127_5384699_0	1124780.ANNU01000028_gene951	5.197e-199	628.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
DTH2_k127_5384699_2	694427.Palpr_2546	4.468e-155	493.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,2FM2X@200643|Bacteroidia,22WIA@171551|Porphyromonadaceae	976|Bacteroidetes	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH2_k127_5384699_3	762984.HMPREF9445_00427	1.073e-77	263.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,2FMA4@200643|Bacteroidia,4ANMW@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
DTH2_k127_5385096_10	1004149.AFOE01000052_gene252	7.962e-07	60.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,1I0KC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DTH2_k127_5385096_11	313598.MED152_10660	4.549e-05	54.0	COG2356@1|root,COG2356@2|Bacteria,4PMBJ@976|Bacteroidetes,1IJQS@117743|Flavobacteriia,3VWW7@52959|Polaribacter	976|Bacteroidetes	L	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5385096_6	1453500.AT05_08815	2.722e-14	80.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DTH2_k127_5385096_8	1250005.PHEL85_0319	5.482e-12	76.0	COG1404@1|root,COG1404@2|Bacteria,4PMB6@976|Bacteroidetes,1IJQ9@117743|Flavobacteriia,3VX5R@52959|Polaribacter	976|Bacteroidetes	O	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DTH2_k127_5385096_9	760192.Halhy_1888	4.415e-09	66.0	COG1361@1|root,COG4733@1|root,COG1361@2|Bacteria,COG4733@2|Bacteria,4P6KE@976|Bacteroidetes	976|Bacteroidetes	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5385096_3	1484460.JSWG01000008_gene1892	2.749e-139	462.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH2_k127_5385096_4	755732.Fluta_1284	6.102e-138	466.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_5385096_0	1408473.JHXO01000013_gene557	1.156e-311	974.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,2G3H3@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_5385096_2	1408433.JHXV01000004_gene3388	1.282e-147	495.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_5385096_1	1408473.JHXO01000010_gene3507	2.835e-282	900.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DTH2_k127_5385096_7	1392498.JQLH01000001_gene3052	4.773e-14	76.0	COG1826@1|root,COG1826@2|Bacteria,4NSAK@976|Bacteroidetes,1I40K@117743|Flavobacteriia,2PHJI@252356|Maribacter	976|Bacteroidetes	U	mttA/Hcf106 family	-	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_540661_3	313598.MED152_05755	6.312e-12	75.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1HX6B@117743|Flavobacteriia,3VV8U@52959|Polaribacter	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
DTH2_k127_540661_1	1166018.FAES_0008	2.057e-38	147.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,47PPW@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH2_k127_540661_0	485918.Cpin_6479	1.141e-72	253.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1IQAP@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_540661_2	929556.Solca_3744	2.37e-32	136.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,1ISCX@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_5416544_5	1380384.JADN01000003_gene479	6.594e-24	108.0	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
DTH2_k127_5416544_4	313606.M23134_02965	4.502e-25	119.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NJKM@976|Bacteroidetes,47NZZ@768503|Cytophagia	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_5416544_2	1380384.JADN01000003_gene479	1.902e-82	292.0	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
DTH2_k127_5416544_0	1237149.C900_01769	1.137e-314	974.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_5416544_3	755732.Fluta_0799	5.708e-56	204.0	28NAE@1|root,2ZBE7@2|Bacteria,4NJNX@976|Bacteroidetes,1I6YH@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (Porph_ging)	-	-	-	-	-	-	-	-	-	-	-	-	Porph_ging
DTH2_k127_5416544_1	755732.Fluta_0800	7.103e-214	694.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,1HX7Z@117743|Flavobacteriia,2PAQ0@246874|Cryomorphaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
DTH2_k127_5426910_0	1313421.JHBV01000030_gene2269	5.712e-122	418.0	COG4783@1|root,COG4783@2|Bacteria,4NM0X@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH2_k127_5426910_1	755732.Fluta_2506	1.045e-44	181.0	2DBNY@1|root,2ZA6F@2|Bacteria,4NH2P@976|Bacteroidetes,1I47S@117743|Flavobacteriia,2PAQ9@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5445098_4	319236.JCM19294_114	9.622e-07	53.0	COG1404@1|root,COG1404@2|Bacteria,4NM0U@976|Bacteroidetes,1I0NM@117743|Flavobacteriia,3HKCK@363408|Nonlabens	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
DTH2_k127_5445098_0	1454007.JAUG01000022_gene1255	6.645e-230	720.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1IPBW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DTH2_k127_5445098_3	153721.MYP_1627	1.688e-38	157.0	COG0460@1|root,COG0460@2|Bacteria	2|Bacteria	E	homoserine dehydrogenase activity	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06610	ACT,Homoserine_dh,NAD_binding_3
DTH2_k127_5445098_2	1123248.KB893315_gene3022	7.291e-46	190.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_5445098_1	700598.Niako_5053	5.703e-51	206.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_5475550_1	742733.HMPREF9469_05294	1.252e-80	275.0	COG3958@1|root,COG3958@2|Bacteria	2|Bacteria	G	transketolase activity	fas3	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_5475550_0	877418.ATWV01000008_gene830	3.045e-86	296.0	COG0451@1|root,COG0451@2|Bacteria,2J8W6@203691|Spirochaetes	203691|Spirochaetes	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH2_k127_5475550_2	929713.NIASO_20300	9.512e-66	231.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_24,TylF
DTH2_k127_5510307_3	388413.ALPR1_03945	2.734e-10	64.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,47PRT@768503|Cytophagia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
DTH2_k127_5510307_0	509635.N824_18545	3.124e-303	951.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH2_k127_5510307_2	984262.SGRA_3487	6.029e-15	83.0	2DS3S@1|root,33EDT@2|Bacteria,4NY8U@976|Bacteroidetes,1IUQ6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5510307_1	679935.Alfi_2829	4.386e-228	713.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_5518975_5	1408433.JHXV01000017_gene1616	8.95e-113	376.0	COG2199@1|root,COG3706@2|Bacteria,4PPWN@976|Bacteroidetes	976|Bacteroidetes	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5518975_2	1408433.JHXV01000017_gene1615	1.806e-168	539.0	COG1215@1|root,COG1215@2|Bacteria,4PIA1@976|Bacteroidetes,1IFXS@117743|Flavobacteriia,2PC4R@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
DTH2_k127_5518975_1	1408433.JHXV01000020_gene3537	2.433e-177	586.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,1IKWF@117743|Flavobacteriia,2PBV8@246874|Cryomorphaceae	976|Bacteroidetes	M	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH2_k127_5518975_7	714943.Mucpa_3685	1.003e-84	286.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,1IPGI@117747|Sphingobacteriia	976|Bacteroidetes	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	-	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH2_k127_5518975_11	1347342.BN863_23850	7.959e-55	196.0	COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,1I1Z5@117743|Flavobacteriia	976|Bacteroidetes	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
DTH2_k127_5518975_15	269797.Mbar_A3447	3.514e-37	163.0	arCOG02348@1|root,arCOG02377@1|root,arCOG02348@2157|Archaea,arCOG02377@2157|Archaea,2Y7NQ@28890|Euryarchaeota,2NAR2@224756|Methanomicrobia	224756|Methanomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS_3,PAS_9
DTH2_k127_5518975_3	313606.M23134_06114	2.204e-127	444.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_5518975_0	1408473.JHXO01000009_gene3355	1.039e-215	678.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,2FNPD@200643|Bacteroidia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DTH2_k127_5518975_4	1150600.ADIARSV_4269	5.913e-117	384.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IQB8@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
DTH2_k127_5518975_14	485917.Phep_2186	1.006e-46	178.0	COG0737@1|root,COG0737@2|Bacteria,4NR6D@976|Bacteroidetes,1ITBW@117747|Sphingobacteriia	976|Bacteroidetes	F	5'-nucleotidase	ushA	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
DTH2_k127_5518975_13	1408813.AYMG01000019_gene1778	1.278e-47	173.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1IT5E@117747|Sphingobacteriia	976|Bacteroidetes	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_5518975_16	1191523.MROS_1043	9.994e-34	132.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DTH2_k127_5518975_10	376686.Fjoh_4420	1.25e-65	227.0	2DBYA@1|root,2ZBU9@2|Bacteria,4NNGM@976|Bacteroidetes,1I19X@117743|Flavobacteriia,2NVW4@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5518975_8	1094466.KQS_04190	5.434e-71	245.0	COG0500@1|root,COG2226@2|Bacteria,4NJ84@976|Bacteroidetes,1HXEK@117743|Flavobacteriia,2NVZW@237|Flavobacterium	976|Bacteroidetes	Q	(SAM)-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,NodS
DTH2_k127_5518975_9	1356852.N008_16220	3.721e-69	240.0	COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,47XMI@768503|Cytophagia	976|Bacteroidetes	U	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DTH2_k127_5518975_12	1519464.HY22_09850	7.785e-51	183.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
DTH2_k127_5518975_6	929556.Solca_1288	1.438e-96	321.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH2_k127_5518975_17	760192.Halhy_4076	4.349e-21	95.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPM9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_552587_0	945713.IALB_0002	2.133e-148	476.0	COG0592@1|root,COG0592@2|Bacteria	2|Bacteria	L	DNA-directed DNA polymerase activity	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DTH2_k127_552587_1	945713.IALB_0003	1.358e-124	409.0	COG1195@1|root,COG1195@2|Bacteria	2|Bacteria	L	single-stranded DNA binding	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03629,ko:K07459	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
DTH2_k127_552587_3	1191523.MROS_1038	2.391e-12	71.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
DTH2_k127_552587_2	945713.IALB_0005	1.71e-89	297.0	COG0187@1|root,COG0187@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_5548361_0	1123248.KB893343_gene9	3.907e-65	249.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_5582_0	1121129.KB903360_gene3385	3.219e-202	644.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,2FNAU@200643|Bacteroidia,22W8Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Penicillin-binding Protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DTH2_k127_5582_1	714943.Mucpa_1920	6.813e-126	405.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DTH2_k127_5582_2	1218108.KB908299_gene3306	9.579e-119	383.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1HWRK@117743|Flavobacteriia	976|Bacteroidetes	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DTH2_k127_5587793_0	929556.Solca_3146	1.373e-158	508.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IQD6@117747|Sphingobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_5587793_1	1121887.AUDK01000008_gene1203	7.567e-90	320.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1ICYX@117743|Flavobacteriia,2NW87@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_5587793_2	485918.Cpin_2043	3.018e-11	65.0	COG3531@1|root,COG3531@2|Bacteria,4NQKI@976|Bacteroidetes,1IXJ5@117747|Sphingobacteriia	976|Bacteroidetes	O	Protein-disulfide isomerase	dsbC	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	DSBA,Thioredoxin_5
DTH2_k127_564812_9	143224.JQMD01000002_gene2283	7.11e-21	102.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
DTH2_k127_564812_1	1406840.Q763_07090	1.518e-121	394.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,1HWKT@117743|Flavobacteriia,2NTPU@237|Flavobacterium	976|Bacteroidetes	S	Pyrophosphatase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
DTH2_k127_564812_6	926549.KI421517_gene3615	2.809e-58	207.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,47QV5@768503|Cytophagia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
DTH2_k127_564812_8	1191523.MROS_0708	2.438e-38	151.0	2D6MI@1|root,32TMJ@2|Bacteria	2|Bacteria	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
DTH2_k127_564812_2	643867.Ftrac_2550	2.86e-97	323.0	COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_564812_3	1121904.ARBP01000006_gene3993	1.873e-88	303.0	COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
DTH2_k127_564812_0	929562.Emtol_3085	9.769e-190	610.0	COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
DTH2_k127_564812_4	1237149.C900_01428	4.114e-74	251.0	COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,47P72@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DTH2_k127_564812_7	1120968.AUBX01000009_gene452	1.294e-53	199.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,47KFS@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
DTH2_k127_564812_5	553177.CAPSP0001_0498	5.986e-67	250.0	COG5263@1|root,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,1HX7Q@117743|Flavobacteriia,1ETIA@1016|Capnocytophaga	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_5651435_1	616991.JPOO01000003_gene1700	8.709e-283	872.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
DTH2_k127_5651435_0	616991.JPOO01000003_gene1701	0.0	2166.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
DTH2_k127_5651435_2	616991.JPOO01000003_gene1702	5.182e-59	216.0	COG2010@1|root,COG2010@2|Bacteria,4P8QV@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_5651435_3	1250232.JQNJ01000001_gene2761	3.702e-44	169.0	COG0664@1|root,COG0664@2|Bacteria,4NJR1@976|Bacteroidetes,1HZZA@117743|Flavobacteriia	976|Bacteroidetes	K	Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_5657179_0	1408433.JHXV01000029_gene3103	1.911e-17	96.0	COG3210@1|root,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes,1I0AY@117743|Flavobacteriia	976|Bacteroidetes	U	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_566029_7	1237149.C900_02150	3.952e-29	122.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,47R7Q@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH2_k127_566029_5	1121904.ARBP01000002_gene7016	7.986e-41	162.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,47XGN@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_566029_4	1237149.C900_03829	6.221e-50	188.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
DTH2_k127_566029_1	1267211.KI669560_gene1666	6.839e-139	460.0	COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes	976|Bacteroidetes	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans
DTH2_k127_566029_8	1158294.JOMI01000003_gene2464	6.345e-20	96.0	COG3449@1|root,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,GyrI-like,HTH_18,SOUL
DTH2_k127_566029_11	1121012.AUKX01000022_gene2400	2.292e-08	62.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia,23HKG@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_566029_3	1270193.JARP01000001_gene2250	8.523e-54	196.0	2C6BU@1|root,32S87@2|Bacteria,4NRX1@976|Bacteroidetes,1I6S7@117743|Flavobacteriia,2NYWP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_566029_6	1121897.AUGO01000002_gene2111	1.527e-39	158.0	292U1@1|root,2ZQBP@2|Bacteria,4NNH4@976|Bacteroidetes,1I28S@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_566029_9	1124780.ANNU01000042_gene611	3.762e-14	77.0	2D4Y8@1|root,32THV@2|Bacteria,4NTRX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_566029_2	471854.Dfer_5316	2.009e-110	367.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
DTH2_k127_566029_0	1121898.Q766_05980	2.399e-143	498.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
DTH2_k127_566029_12	391603.FBALC1_12557	4.911e-05	57.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.181,3.2.1.8,3.2.1.83	ko:K01181,ko:K20832,ko:K20846	-	-	-	-	ko00000,ko01000	-	GH16	-	CBM_6,Glyco_hydro_16,RicinB_lectin_2
DTH2_k127_5674202_6	255470.cbdbA1238	2.584e-31	128.0	COG0477@1|root,COG0477@2|Bacteria,2G7KE@200795|Chloroflexi,34CVC@301297|Dehalococcoidia	301297|Dehalococcoidia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
DTH2_k127_5674202_3	926562.Oweho_2578	3.077e-112	387.0	COG2931@1|root,COG2931@2|Bacteria,4P2B3@976|Bacteroidetes,1I8WB@117743|Flavobacteriia,2PBTD@246874|Cryomorphaceae	976|Bacteroidetes	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5674202_1	1121373.KB903662_gene54	2.434e-155	499.0	COG2081@1|root,COG2081@2|Bacteria,4NFQ9@976|Bacteroidetes,47KHX@768503|Cytophagia	976|Bacteroidetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH2_k127_5674202_2	1237149.C900_03832	1.294e-118	385.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH2_k127_5674202_4	700598.Niako_1886	1.132e-106	351.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1IQ62@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH2_k127_5674202_5	1237149.C900_03830	2.915e-89	304.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47T9B@768503|Cytophagia	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_5674202_7	1454007.JAUG01000014_gene1834	4.41e-05	51.0	2DQF8@1|root,336GX@2|Bacteria,4NVXD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5674202_0	946077.W5A_07717	5.798e-287	897.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DTH2_k127_5721600_4	398720.MED217_18030	5.785e-50	183.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia,2XISU@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Transglycosylase	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DTH2_k127_5721600_7	694427.Palpr_2407	7.491e-33	133.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,2FUJF@200643|Bacteroidia,22YQC@171551|Porphyromonadaceae	976|Bacteroidetes	S	GldH lipoprotein	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
DTH2_k127_5721600_2	143224.JQMD01000002_gene3230	1.838e-144	471.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
DTH2_k127_5721600_3	1347393.HG726030_gene7513	2.706e-105	353.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,2FPCQ@200643|Bacteroidia,4AMUD@815|Bacteroidaceae	976|Bacteroidetes	L	COG2812 DNA polymerase III gamma tau subunits	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
DTH2_k127_5721600_5	562970.Btus_0243	1.962e-42	164.0	COG4194@1|root,COG5658@1|root,COG4194@2|Bacteria,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,4HJDZ@91061|Bacilli,278K6@186823|Alicyclobacillaceae	91061|Bacilli	S	SdpI/YhfL protein family	yvaZ	GO:0008150,GO:0009636,GO:0042221,GO:0050896	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
DTH2_k127_5721600_8	1267211.KI669560_gene226	4.202e-31	124.0	COG0640@1|root,COG0640@2|Bacteria,4NS8H@976|Bacteroidetes,1IZ7N@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DTH2_k127_5721600_1	1150600.ADIARSV_2746	6.225e-179	568.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DTH2_k127_5721600_10	314282.PCNPT3_00880	2.267e-06	61.0	COG1523@1|root,COG2911@1|root,COG1523@2|Bacteria,COG2911@2|Bacteria,1PF6A@1224|Proteobacteria,1RWSX@1236|Gammaproteobacteria,2QJ0N@267894|Psychromonadaceae	1236|Gammaproteobacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5721600_6	714943.Mucpa_3517	8.411e-42	157.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1ISZQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
DTH2_k127_5721600_0	714943.Mucpa_3824	3.051e-190	604.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
DTH2_k127_5721600_9	1121957.ATVL01000010_gene440	6.224e-11	63.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_5727275_0	69279.BG36_13100	1.559e-258	810.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,43I8J@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
DTH2_k127_5727275_1	243090.RB11118	1.677e-104	349.0	COG4948@1|root,COG4948@2|Bacteria,2IXEE@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase muconate	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH2_k127_5729840_1	1406840.Q763_08545	3.814e-290	910.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
DTH2_k127_5729840_0	1341181.FLJC2902T_00590	1.126e-321	1005.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,1HX95@117743|Flavobacteriia,2NTHP@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH2_k127_5729840_12	1453505.JASY01000008_gene654	1.67e-75	259.0	COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,1I1FE@117743|Flavobacteriia,2NSMN@237|Flavobacterium	976|Bacteroidetes	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
DTH2_k127_5729840_6	1506583.JQJY01000008_gene4054	4.105e-171	541.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1HXFB@117743|Flavobacteriia,2NTK7@237|Flavobacterium	976|Bacteroidetes	E	Asparaginase	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_5729840_5	1094466.KQS_02305	2.887e-191	611.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1HXU1@117743|Flavobacteriia,2NSHE@237|Flavobacterium	976|Bacteroidetes	G	Pfam Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
DTH2_k127_5729840_2	700598.Niako_4610	3.471e-236	743.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,1IVAT@117747|Sphingobacteriia	976|Bacteroidetes	F	COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
DTH2_k127_5729840_14	1216967.L100_09019	5.013e-54	192.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia,34RDS@308865|Elizabethkingia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_5729840_11	1229487.AMYW01000003_gene1973	4.078e-83	279.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia,2NUTM@237|Flavobacterium	976|Bacteroidetes	S	YeeE YedE family protein	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_5729840_9	760192.Halhy_2537	1.547e-120	397.0	COG3258@1|root,COG3258@2|Bacteria,4NGIH@976|Bacteroidetes,1IRZ3@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrom_C,Cytochrome_CBB3
DTH2_k127_5729840_10	483215.BACFIN_08312	1.952e-110	365.0	COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae	976|Bacteroidetes	GK	Psort location Cytoplasmic, score 9.26	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH2_k127_5729840_4	714943.Mucpa_5862	9.343e-211	666.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IPM2@117747|Sphingobacteriia	976|Bacteroidetes	G	COG0738 Fucose permease	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
DTH2_k127_5729840_8	1168034.FH5T_07035	4.01e-124	410.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,2FPNI@200643|Bacteroidia	976|Bacteroidetes	M	3-Deoxy-D-manno-octulosonic-acid transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
DTH2_k127_5729840_15	755732.Fluta_2041	1.974e-52	194.0	2EA9Q@1|root,334E4@2|Bacteria,4NX5I@976|Bacteroidetes,1IASC@117743|Flavobacteriia,2PB5U@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5729840_7	926562.Oweho_1671	7.129e-168	534.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia,2PA9E@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM DegT DnrJ EryC1 StrS aminotransferase family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_5729840_3	1121904.ARBP01000003_gene6520	3.12e-220	689.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH2_k127_5729840_13	1450525.JATV01000004_gene96	1.893e-66	227.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia,2NSCX@237|Flavobacterium	976|Bacteroidetes	GM	dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_5735284_4	1107311.Q767_08890	7.405e-141	450.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1I16J@117743|Flavobacteriia,2NSWN@237|Flavobacterium	976|Bacteroidetes	P	permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DTH2_k127_5735284_3	1492738.FEM21_02250	3.536e-185	586.0	COG0226@1|root,COG0573@1|root,COG0226@2|Bacteria,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,1HYFF@117743|Flavobacteriia,2NS7H@237|Flavobacterium	976|Bacteroidetes	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,PBP_like_2
DTH2_k127_5735284_5	1235803.C825_01254	3.461e-117	382.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,2FMW1@200643|Bacteroidia,22X86@171551|Porphyromonadaceae	976|Bacteroidetes	P	Bacterial extracellular solute-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_5735284_7	927658.AJUM01000037_gene2071	4.372e-88	306.0	COG3746@1|root,COG3746@2|Bacteria,4NIRE@976|Bacteroidetes,2FR58@200643|Bacteroidia	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH2_k127_5735284_1	760192.Halhy_3198	4.275e-227	719.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes	976|Bacteroidetes	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) multisubunit Na H antiporter MnhA subunit	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH2_k127_5735284_0	760192.Halhy_3199	0.0	1191.0	COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,1IWN3@117747|Sphingobacteriia	976|Bacteroidetes	P	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
DTH2_k127_5735284_6	760192.Halhy_3200	8.055e-111	361.0	COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1IP6Z@117747|Sphingobacteriia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DTH2_k127_5735284_2	761193.Runsl_2495	1.552e-192	612.0	COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0659 Sulfate permease and related transporter (MFS superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
DTH2_k127_5767374_9	706587.Desti_4506	1.66e-76	265.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N,ECH_1
DTH2_k127_5767374_5	1244869.H261_03138	1.494e-111	372.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
DTH2_k127_5767374_0	85643.Tmz1t_2950	7.394e-173	552.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2W3EH@28216|Betaproteobacteria,2KZ1E@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
DTH2_k127_5767374_7	316055.RPE_0606	1.087e-108	369.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
DTH2_k127_5767374_3	1237149.C900_04255	1.991e-134	437.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47N5F@768503|Cytophagia	976|Bacteroidetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DTH2_k127_5767374_8	316057.RPD_1535	3.149e-79	273.0	COG1924@1|root,COG1924@2|Bacteria,1MY0N@1224|Proteobacteria,2U4V9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
DTH2_k127_5767374_17	745718.JADT01000017_gene1057	1.513e-05	57.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	fpp1	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
DTH2_k127_5767374_10	406817.XNC1_2156	5.879e-74	271.0	COG1022@1|root,COG3321@1|root,COG1022@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
DTH2_k127_5767374_2	443144.GM21_2867	2.342e-145	471.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
DTH2_k127_5767374_12	1125863.JAFN01000001_gene583	4.946e-48	194.0	COG1893@1|root,COG1893@2|Bacteria,1R96Z@1224|Proteobacteria,42PU0@68525|delta/epsilon subdivisions,2WK47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DTH2_k127_5767374_14	1125863.JAFN01000001_gene2399	5.666e-38	162.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	TIGRFAM CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DTH2_k127_5767374_4	1121918.ARWE01000001_gene3599	2.085e-128	423.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WMIY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	bktB	-	2.3.1.16	ko:K07508	ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212	M00085,M00087	R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_5767374_16	1124780.ANNU01000013_gene3870	3.634e-26	112.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,47R42@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_5767374_6	1232410.KI421412_gene166	2.281e-109	364.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH2_k127_5767374_1	1187851.A33M_3194	5.473e-159	508.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_5767374_11	706587.Desti_1480	9.503e-74	257.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_5767374_15	945713.IALB_1082	6.317e-34	147.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.1.3.1,3.1.3.5,3.1.3.8,3.6.1.45	ko:K01077,ko:K01083,ko:K07004,ko:K11751	ko00230,ko00240,ko00562,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00562,map00730,map00760,map00790,map01100,map01110,map02020	M00126	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R03371,R04620	RC00017,RC00078	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	5_nucleotid_C,Calx-beta,Phytase-like
DTH2_k127_5767374_13	1122605.KB893645_gene1205	1.028e-44	170.0	COG0664@1|root,COG0664@2|Bacteria,4NJR1@976|Bacteroidetes,1IQRM@117747|Sphingobacteriia	976|Bacteroidetes	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_5767907_0	762903.Pedsa_0610	3.374e-153	489.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1IPAW@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_5767907_1	1408473.JHXO01000005_gene1826	4.504e-75	278.0	2DQUH@1|root,338RF@2|Bacteria,4P2QJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5767907_2	1408433.JHXV01000017_gene1617	5.384e-65	235.0	2F61I@1|root,33YJY@2|Bacteria,4P4C0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5769891_10	153721.MYP_4263	4.523e-41	153.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,47RR4@768503|Cytophagia	976|Bacteroidetes	IQ	3-oxoacyl-ACP synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5769891_12	688246.Premu_2869	1.93e-28	116.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,2FTE9@200643|Bacteroidia	976|Bacteroidetes	IQ	acyl carrier protein	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_5769891_2	153721.MYP_4265	5.536e-158	508.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,47N4W@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_5769891_6	714943.Mucpa_6800	1.737e-106	355.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
DTH2_k127_5769891_7	697282.Mettu_0412	5.461e-97	323.0	COG0726@1|root,COG0726@2|Bacteria,1PGPG@1224|Proteobacteria,1SPJC@1236|Gammaproteobacteria,1XGNN@135618|Methylococcales	135618|Methylococcales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_5769891_9	1313421.JHBV01000138_gene1221	2.224e-51	189.0	COG2834@1|root,COG2834@2|Bacteria,4NT30@976|Bacteroidetes,1IU2D@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
DTH2_k127_5769891_13	1121898.Q766_18670	4.256e-27	118.0	29ETG@1|root,301R8@2|Bacteria,4NS07@976|Bacteroidetes,1IID1@117743|Flavobacteriia,2NUQA@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5769891_14	153721.MYP_4270	1.085e-25	110.0	COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,47SUB@768503|Cytophagia	976|Bacteroidetes	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
DTH2_k127_5769891_5	1237149.C900_02929	9.694e-121	400.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,47MJC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
DTH2_k127_5769891_0	153721.MYP_4272	0.0	1206.0	COG0204@1|root,COG4258@1|root,COG0204@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,47P2T@768503|Cytophagia	976|Bacteroidetes	I	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
DTH2_k127_5769891_1	153721.MYP_4273	1.325e-208	659.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,47K5X@768503|Cytophagia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_5769891_3	382464.ABSI01000010_gene3762	2.004e-140	452.0	COG0667@1|root,COG0667@2|Bacteria,46U3T@74201|Verrucomicrobia,2ITTY@203494|Verrucomicrobiae	2|Bacteria	C	Aldo/keto reductase family	-	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH2_k127_5769891_4	1313421.JHBV01000043_gene3177	1.153e-121	400.0	COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,1IQ7F@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
DTH2_k127_5769891_8	1408433.JHXV01000009_gene1285	1.08e-65	236.0	COG3637@1|root,COG3637@2|Bacteria,4PJ16@976|Bacteroidetes,1ICQ3@117743|Flavobacteriia,2PBMQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5769891_11	945713.IALB_2866	3.613e-36	142.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yiiD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564	-	ko:K06323	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
DTH2_k127_5769891_15	1144313.PMI10_03866	7.374e-11	64.0	COG1893@1|root,COG1893@2|Bacteria,4NMFF@976|Bacteroidetes,1I3H3@117743|Flavobacteriia,2NUQF@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DTH2_k127_5786873_1	945713.IALB_2228	2.675e-53	195.0	COG0471@1|root,COG0471@2|Bacteria	2|Bacteria	P	metal ion transport	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
DTH2_k127_5786873_4	1408433.JHXV01000008_gene204	0.000154	49.0	292FT@1|root,2ZPZZ@2|Bacteria,4P8JD@976|Bacteroidetes,1IB9V@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5786873_0	742767.HMPREF9456_01598	4.094e-125	407.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,2FN5I@200643|Bacteroidia,22VZZ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
DTH2_k127_5786873_2	153721.MYP_4845	2.641e-34	133.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,47V8W@768503|Cytophagia	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_5786873_3	926549.KI421517_gene3757	2.017e-32	128.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_5821200_0	929556.Solca_2311	1.59e-181	572.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes,1IPKA@117747|Sphingobacteriia	976|Bacteroidetes	G	Aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DTH2_k127_5821200_1	1168034.FH5T_04250	9.061e-108	364.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein, OMP85 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_5963137_2	1321774.HMPREF9108_01845	1.525e-24	111.0	2DNIE@1|root,32XP6@2|Bacteria,37CQY@32066|Fusobacteria	32066|Fusobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5963137_1	504472.Slin_6155	1.191e-66	233.0	2B7JP@1|root,320QE@2|Bacteria,4NZGU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5963137_0	880071.Fleli_2427	7.888e-147	469.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4,HNH_5
DTH2_k127_5963137_3	1408433.JHXV01000025_gene4054	3.287e-18	96.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,2PB8R@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,TSP_3
DTH2_k127_5965350_5	742817.HMPREF9449_00919	6.086e-06	52.0	COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0E9@200643|Bacteroidia,23266@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
DTH2_k127_5965350_3	1237149.C900_01076	8.425e-29	123.0	COG0642@1|root,COG2205@2|Bacteria,4NX2D@976|Bacteroidetes,47T5N@768503|Cytophagia	976|Bacteroidetes	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
DTH2_k127_5965350_0	755732.Fluta_0012	1.911e-113	386.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,1HYI0@117743|Flavobacteriia,2PBG5@246874|Cryomorphaceae	976|Bacteroidetes	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140,Plug
DTH2_k127_5965350_1	1408813.AYMG01000001_gene3694	1.424e-54	197.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_5965350_4	1235803.C825_03034	1.399e-25	121.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,22XTD@171551|Porphyromonadaceae	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_5965350_2	468059.AUHA01000002_gene591	8.229e-38	149.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,1IRY7@117747|Sphingobacteriia	976|Bacteroidetes	M	Nlp p60 protein	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
DTH2_k127_596662_4	1122176.KB903532_gene2534	7.082e-97	323.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1ISRU@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_596662_0	755732.Fluta_4067	1.054e-220	692.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2PBCM@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_596662_3	743722.Sph21_3072	6.771e-100	336.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,1IP2P@117747|Sphingobacteriia	976|Bacteroidetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
DTH2_k127_596662_1	1519464.HY22_08950	2.534e-214	688.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_596662_2	926562.Oweho_1011	1.813e-196	633.0	COG0457@1|root,COG3303@1|root,COG0457@2|Bacteria,COG3303@2|Bacteria,4NDTY@976|Bacteroidetes,1HXS9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_2,TPR_8
DTH2_k127_596662_6	1121875.KB907548_gene1201	1.325e-59	211.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,1I27H@117743|Flavobacteriia	976|Bacteroidetes	J	acetyltransferase	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
DTH2_k127_596662_5	926549.KI421517_gene229	5.61e-84	284.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
DTH2_k127_5967243_0	1270196.JCKI01000008_gene1557	0.0	1094.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
DTH2_k127_5967243_3	509635.N824_04920	2.42e-181	594.0	COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,1IPVY@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_5967243_6	1124780.ANNU01000017_gene1910	2.638e-93	313.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,47M03@768503|Cytophagia	976|Bacteroidetes	P	Periplasmic binding protein	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
DTH2_k127_5967243_2	1358423.N180_18965	2.065e-215	676.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
DTH2_k127_5967243_5	411477.PARMER_03556	9.654e-122	403.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,2FMHC@200643|Bacteroidia,22WJ1@171551|Porphyromonadaceae	976|Bacteroidetes	M	ABC transporter permease	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_5967243_4	1123059.KB823013_gene496	8.429e-144	466.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
DTH2_k127_5967243_7	1237149.C900_03516	6.779e-66	240.0	COG3509@1|root,COG4733@1|root,COG3509@2|Bacteria,COG4733@2|Bacteria,4NR4C@976|Bacteroidetes	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
DTH2_k127_5967243_9	927658.AJUM01000037_gene2191	2.084e-31	132.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,2G24N@200643|Bacteroidia,3XJR5@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5967243_1	509635.N824_10045	2.39e-266	830.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH2_k127_5967243_10	215803.DB30_7899	8.35e-09	61.0	2DN1Z@1|root,32V20@2|Bacteria,1Q8W3@1224|Proteobacteria,43E1M@68525|delta/epsilon subdivisions,2WZFP@28221|Deltaproteobacteria,2Z21B@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5967243_8	153721.MYP_252	1.641e-48	181.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
DTH2_k127_5977402_4	1237149.C900_00826	3.93e-43	164.0	2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_10
DTH2_k127_5977402_7	1168065.DOK_02821	9.931e-12	68.0	COG0011@1|root,COG0011@2|Bacteria,1N8R0@1224|Proteobacteria,1SCF3@1236|Gammaproteobacteria,1J71D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	YKOF-related Family	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP,Ykof
DTH2_k127_5977402_3	1041826.FCOL_01155	1.012e-75	260.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,2NTC4@237|Flavobacterium	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
DTH2_k127_5977402_0	153721.MYP_1730	1.647e-310	970.0	COG0550@1|root,COG0550@2|Bacteria,4NE6R@976|Bacteroidetes,47M3S@768503|Cytophagia	976|Bacteroidetes	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
DTH2_k127_5977402_1	468059.AUHA01000002_gene954	2.16e-178	567.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IPVF@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
DTH2_k127_5977402_6	1121405.dsmv_3288	1.318e-15	79.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH2_k127_5977402_2	929556.Solca_0689	3.139e-95	325.0	COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,1IQ1K@117747|Sphingobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_5977402_5	1121904.ARBP01000009_gene4229	2.304e-35	145.0	COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,47WA7@768503|Cytophagia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5990303_7	1433126.BN938_0160	2.439e-09	61.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22V8H@171550|Rikenellaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH2_k127_5990303_1	714943.Mucpa_6112	7.719e-135	450.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1IR9Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
DTH2_k127_5990303_6	1121904.ARBP01000007_gene2910	2.142e-48	182.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes	976|Bacteroidetes	M	tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
DTH2_k127_5990303_3	485917.Phep_1482	8.323e-114	376.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1IR1C@117747|Sphingobacteriia	976|Bacteroidetes	S	von Willebrand factor, type A	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
DTH2_k127_5990303_4	886379.AEWI01000062_gene2298	9.747e-106	352.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,3XJ05@558415|Marinilabiliaceae	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
DTH2_k127_5990303_5	485917.Phep_1480	3.91e-65	234.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1ISTW@117747|Sphingobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5990303_2	1121904.ARBP01000007_gene2905	3.32e-129	417.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH2_k127_5990303_0	709991.Odosp_1181	1.22e-151	482.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,22W2U@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_6045241_1	1408433.JHXV01000030_gene1398	0.0005907	48.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes,1ICNQ@117743|Flavobacteriia,2PBCJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6045241_0	468059.AUHA01000006_gene2856	4.126e-122	402.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
DTH2_k127_605305_2	1453500.AT05_04480	1.616e-25	113.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,fn3
DTH2_k127_605305_0	1094466.KQS_10385	2.129e-228	721.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1HY2B@117743|Flavobacteriia,2NU2C@237|Flavobacterium	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_605305_1	468059.AUHA01000003_gene1959	6.493e-135	436.0	COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,1IQBU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_6059910_4	755732.Fluta_2340	1.713e-101	367.0	COG3291@1|root,COG4935@1|root,COG5492@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5492@2|Bacteria,4NDZQ@976|Bacteroidetes	976|Bacteroidetes	H	Gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Ig_3
DTH2_k127_6059910_2	929556.Solca_1436	1.408e-125	408.0	COG0408@1|root,COG0408@2|Bacteria,4NFZS@976|Bacteroidetes,1IQE1@117747|Sphingobacteriia	976|Bacteroidetes	H	coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
DTH2_k127_6059910_7	1408473.JHXO01000004_gene86	9.537e-61	231.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,2FNR1@200643|Bacteroidia	976|Bacteroidetes	M	LysM domain protein	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
DTH2_k127_6059910_0	755732.Fluta_2924	6.381e-267	828.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1HX9A@117743|Flavobacteriia,2PAFZ@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
DTH2_k127_6059910_8	1408433.JHXV01000001_gene721	2.512e-39	161.0	COG0457@1|root,COG0457@2|Bacteria,4PJHB@976|Bacteroidetes,1IMQ8@117743|Flavobacteriia,2PB7I@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_6059910_1	714943.Mucpa_1091	8.978e-173	548.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1INW2@117747|Sphingobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DTH2_k127_6059910_6	1408433.JHXV01000001_gene719	1.089e-63	222.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia,2PAV5@246874|Cryomorphaceae	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH2_k127_6059910_3	411477.PARMER_03044	2.933e-108	353.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,2FM8U@200643|Bacteroidia,22WI0@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DTH2_k127_6059910_5	1380384.JADN01000003_gene479	1.857e-65	243.0	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
DTH2_k127_6059910_9	755732.Fluta_1284	4.084e-07	53.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_6079432_8	762903.Pedsa_2755	1.573e-71	248.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DTH2_k127_6079432_2	926562.Oweho_2357	8.499e-202	634.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1HWXE@117743|Flavobacteriia,2PA7W@246874|Cryomorphaceae	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_6079432_15	927658.AJUM01000034_gene225	6.05e-37	140.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,2FTWG@200643|Bacteroidia,3XKCJ@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_6079432_11	1123248.KB893319_gene3958	2.132e-64	225.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
DTH2_k127_6079432_7	1121897.AUGO01000001_gene1678	2.94e-72	248.0	COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1HXJM@117743|Flavobacteriia,2NTN9@237|Flavobacterium	976|Bacteroidetes	U	UPF0056 membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
DTH2_k127_6079432_12	1168034.FH5T_06725	6.622e-64	222.0	COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,2FSJX@200643|Bacteroidia	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
DTH2_k127_6079432_4	391587.KAOT1_22051	1.757e-105	347.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1HY8Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_6079432_1	926549.KI421517_gene1115	1.248e-214	674.0	COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,47K0I@768503|Cytophagia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
DTH2_k127_6079432_13	468059.AUHA01000002_gene654	2.756e-54	196.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,1ISYY@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
DTH2_k127_6079432_9	485918.Cpin_3687	4.032e-71	253.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_6079432_14	445970.ALIPUT_01369	1.447e-46	170.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia,22UGY@171550|Rikenellaceae	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
DTH2_k127_6079432_6	1168034.FH5T_06030	3.994e-89	302.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,2FN90@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
DTH2_k127_6079432_5	1168034.FH5T_06025	2.832e-105	348.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,2FN7D@200643|Bacteroidia	976|Bacteroidetes	G	Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
DTH2_k127_6079432_16	743722.Sph21_1634	1.305e-18	99.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes,1IRXG@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
DTH2_k127_6079432_0	762903.Pedsa_2820	8e-292	905.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DTH2_k127_6079432_10	926549.KI421517_gene828	6.564e-71	243.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
DTH2_k127_6079432_3	1122176.KB903531_gene2986	9.348e-166	547.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_6093882_3	1406840.Q763_09950	3.198e-57	201.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2NWCA@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DTH2_k127_6093882_4	1500281.JQKZ01000013_gene424	2.049e-05	55.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CUB,CW_7,GH97_N,Glucosaminidase,Reprolysin_5
DTH2_k127_6093882_1	468059.AUHA01000002_gene282	6.091e-198	632.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH2_k127_6093882_2	929556.Solca_0555	3.138e-104	344.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1INN2@117747|Sphingobacteriia	976|Bacteroidetes	NU	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_6093882_0	1270193.JARP01000001_gene2339	3.252e-313	967.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1HZCT@117743|Flavobacteriia,2NTX8@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
DTH2_k127_6110593_9	679190.HMPREF0650_1787	0.0001298	49.0	2BVI0@1|root,303Y1@2|Bacteria,4NP8P@976|Bacteroidetes,2FTDX@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6110593_3	743722.Sph21_0974	1.2e-59	213.0	COG2249@1|root,COG2249@2|Bacteria,4NG9N@976|Bacteroidetes,1IVN4@117747|Sphingobacteriia	976|Bacteroidetes	C	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
DTH2_k127_6110593_5	376686.Fjoh_1881	6.966e-45	172.0	COG2067@1|root,COG2067@2|Bacteria,4NXNU@976|Bacteroidetes,1IACV@117743|Flavobacteriia,2NV66@237|Flavobacterium	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
DTH2_k127_6110593_0	865937.Gilli_2940	1.965e-153	490.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,1HYRT@117743|Flavobacteriia	976|Bacteroidetes	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_2,ADH_zinc_N_2
DTH2_k127_6110593_6	1121904.ARBP01000009_gene4385	1.331e-37	155.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6110593_7	1123248.KB893337_gene2449	3.608e-19	94.0	COG0454@1|root,COG0456@2|Bacteria,4NQIV@976|Bacteroidetes,1ITRA@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
DTH2_k127_6110593_4	1270193.JARP01000004_gene1465	5.907e-58	205.0	COG4119@1|root,COG4119@2|Bacteria,4NRRR@976|Bacteroidetes,1I9FM@117743|Flavobacteriia,2NVD1@237|Flavobacterium	976|Bacteroidetes	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_6110593_1	269798.CHU_1297	1.9e-75	256.0	COG0262@1|root,COG0262@2|Bacteria,4NQK0@976|Bacteroidetes,47PT4@768503|Cytophagia	976|Bacteroidetes	H	PFAM RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
DTH2_k127_6110593_2	153721.MYP_3970	1.095e-64	225.0	2FDT1@1|root,345TR@2|Bacteria,4P5ST@976|Bacteroidetes,47W7J@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6110593_8	357804.Ping_0849	2.225e-08	55.0	COG0484@1|root,COG0654@1|root,COG0484@2|Bacteria,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,1RQRQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CH	monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
DTH2_k127_6132212_2	1121373.KB903632_gene398	4.432e-88	295.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,47PCQ@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DTH2_k127_6132212_0	555500.I215_07247	2.32e-99	329.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_6132212_1	1168034.FH5T_05860	6.654e-95	322.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,2FKYG@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_6132212_3	313606.M23134_04797	2.133e-19	94.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,47RHF@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_6132212_4	172045.KS04_11365	0.0001056	49.0	2E64P@1|root,330TI@2|Bacteria,4NUW4@976|Bacteroidetes,1I68A@117743|Flavobacteriia,34RPR@308865|Elizabethkingia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
DTH2_k127_6151840_1	1469607.KK073768_gene1902	2.738e-74	258.0	COG1619@1|root,COG1619@2|Bacteria,1G059@1117|Cyanobacteria,1HKA4@1161|Nostocales	1117|Cyanobacteria	V	Peptidase U61, LD-carboxypeptidase A	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
DTH2_k127_6151840_0	1408433.JHXV01000027_gene3728	2.84e-155	514.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_6153489_0	938709.AUSH02000031_gene1200	5.53e-234	728.0	COG2211@1|root,COG2211@2|Bacteria,4NE0X@976|Bacteroidetes	976|Bacteroidetes	G	nucleoside	nupG	-	-	ko:K03289,ko:K11537	-	-	-	-	ko00000,ko02000	2.A.1.10.1,2.A.1.10.2	-	-	Nuc_H_symport
DTH2_k127_6153489_4	929556.Solca_1918	7.622e-75	256.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1IRH8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
DTH2_k127_6153489_2	485918.Cpin_3759	1.288e-110	366.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DTH2_k127_6153489_3	1408433.JHXV01000015_gene1752	5.505e-90	302.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1HX74@117743|Flavobacteriia,2PAQ1@246874|Cryomorphaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DTH2_k127_6153489_5	926562.Oweho_3051	2.207e-64	227.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia,2PAXH@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
DTH2_k127_6153489_1	929556.Solca_1162	4.517e-231	720.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
DTH2_k127_6153489_6	926562.Oweho_3049	1.536e-55	201.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,2PBV2@246874|Cryomorphaceae	976|Bacteroidetes	CO	PFAM AhpC TSA family	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
DTH2_k127_6153489_7	485917.Phep_0109	1.636e-27	126.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPAI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_6183531_0	485917.Phep_3075	1.53e-183	586.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1IPE5@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,HHH_8,PHP
DTH2_k127_6183531_1	1123037.AUDE01000019_gene3324	2.548e-90	317.0	28KN2@1|root,2ZA6D@2|Bacteria,4NG7P@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6198628_1	945713.IALB_1297	1.302e-127	416.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH2_k127_6198628_0	517418.Ctha_0304	1.167e-179	571.0	COG0427@1|root,COG0427@2|Bacteria,1FDQ1@1090|Chlorobi	1090|Chlorobi	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
DTH2_k127_6198628_2	929556.Solca_2058	2.03e-88	305.0	COG0477@1|root,COG2814@2|Bacteria,4NEUU@976|Bacteroidetes,1INWC@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DTH2_k127_6204666_1	1123508.JH636439_gene1132	3.081e-55	202.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
DTH2_k127_6204666_0	526222.Desal_3211	6.364e-244	774.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2M9S9@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	RNA binding S1 domain protein	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
DTH2_k127_624189_6	1137281.D778_00891	2.526e-11	64.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1HY3U@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
DTH2_k127_624189_1	1168289.AJKI01000035_gene3580	4.965e-144	473.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae	976|Bacteroidetes	O	Trypsin	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
DTH2_k127_624189_2	1168034.FH5T_20510	4.207e-142	455.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH2_k127_624189_0	926562.Oweho_1015	3.35e-191	608.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1HXX7@117743|Flavobacteriia,2PAGG@246874|Cryomorphaceae	976|Bacteroidetes	C	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_624189_3	929556.Solca_2726	2.18e-106	353.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH2_k127_624189_4	468059.AUHA01000005_gene2562	9.481e-52	190.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPM9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_6247992_0	1123037.AUDE01000001_gene1961	0.0	1150.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DTH2_k127_6247992_9	1450525.JATV01000001_gene2724	2.529e-23	100.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,1I4E1@117743|Flavobacteriia,2NWPM@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_6247992_4	313606.M23134_00440	1.29e-71	243.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_6247992_5	153721.MYP_1934	2.794e-49	186.0	COG0584@1|root,COG0584@2|Bacteria,4NUR0@976|Bacteroidetes,47S2Q@768503|Cytophagia	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH2_k127_6247992_12	1150600.ADIARSV_2453	9.461e-07	61.0	2EHJH@1|root,32W49@2|Bacteria,4NTI9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6247992_8	1121904.ARBP01000009_gene4385	2.002e-39	163.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6247992_3	515635.Dtur_1285	9.301e-85	299.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
DTH2_k127_6247992_7	1443665.JACA01000007_gene245	1.302e-39	165.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia,2YGNW@290174|Aquimarina	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12,TPR_7,TPR_8
DTH2_k127_6247992_11	208439.AJAP_33575	5.623e-09	70.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria,4E2E3@85010|Pseudonocardiales	201174|Actinobacteria	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,Laminin_G_3,PT-HINT,RHS_repeat
DTH2_k127_6247992_10	1356852.N008_08225	2.511e-22	113.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_6247992_2	1121373.KB903632_gene480	2.195e-93	312.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
DTH2_k127_6247992_1	1122176.KB903537_gene1644	1.09e-93	317.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IQN9@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DTH2_k127_6247992_6	1191523.MROS_1653	1.643e-48	181.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_6277954_5	1408433.JHXV01000018_gene3848	2.238e-18	87.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I7ZV@117743|Flavobacteriia,2PAMN@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_6277954_4	485918.Cpin_6900	2.024e-36	151.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_6277954_0	1313301.AUGC01000001_gene1690	4.941e-181	575.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes	976|Bacteroidetes	E	Aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_6277954_3	1121889.AUDM01000005_gene1694	5.558e-66	234.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1HY0U@117743|Flavobacteriia,2NT6Y@237|Flavobacterium	976|Bacteroidetes	I	Alpha beta hydrolase	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH2_k127_6277954_2	485918.Cpin_6623	5.297e-66	233.0	COG3279@1|root,COG3279@2|Bacteria,4NPFH@976|Bacteroidetes,1IXDB@117747|Sphingobacteriia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_6277954_1	1121373.KB903625_gene3160	8.986e-108	368.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_6369477_1	714943.Mucpa_2200	1.05e-219	688.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
DTH2_k127_6369477_4	153721.MYP_1971	5.27e-184	582.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JQD@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_6369477_0	485917.Phep_3722	5.804e-282	876.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,1IPBZ@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_6369477_30	1348583.ATLH01000029_gene1692	3.068e-56	201.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia,1F95B@104264|Cellulophaga	976|Bacteroidetes	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DTH2_k127_6369477_28	402612.FP0151	2.163e-59	211.0	COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1I1YR@117743|Flavobacteriia	976|Bacteroidetes	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_12,Methyltransf_25,RrnaAD
DTH2_k127_6369477_12	929713.NIASO_05795	2.862e-133	435.0	COG2271@1|root,COG2271@2|Bacteria,4NG3R@976|Bacteroidetes	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
DTH2_k127_6369477_35	1434325.AZQN01000002_gene932	1.389e-24	104.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
DTH2_k127_6369477_29	1121373.KB903665_gene3082	4.202e-57	204.0	COG0431@1|root,COG0431@2|Bacteria,4NN31@976|Bacteroidetes,47SD0@768503|Cytophagia	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH2_k127_6369477_14	1124780.ANNU01000035_gene273	3.161e-129	421.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,47KXF@768503|Cytophagia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_6369477_19	313606.M23134_02864	1.28e-84	285.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
DTH2_k127_6369477_17	269798.CHU_1710	1.714e-102	367.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_6369477_39	762903.Pedsa_2297	1.471e-16	81.0	COG4895@1|root,COG4895@2|Bacteria,4NUT0@976|Bacteroidetes	976|Bacteroidetes	S	conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
DTH2_k127_6369477_18	153721.MYP_2914	2.339e-92	329.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_6369477_5	1185876.BN8_03723	3.934e-179	573.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DTH2_k127_6369477_32	929703.KE386491_gene3265	6.057e-53	190.0	COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,47Y1I@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DTH2_k127_6369477_2	926549.KI421517_gene2264	3.076e-193	617.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,47JP2@768503|Cytophagia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH2_k127_6369477_11	1492737.FEM08_25510	2.26e-134	435.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1I8RM@117743|Flavobacteriia,2NSKJ@237|Flavobacterium	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
DTH2_k127_6369477_36	468059.AUHA01000002_gene472	1.635e-24	106.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,1IUJE@117747|Sphingobacteriia	976|Bacteroidetes	D	CrcB-like protein, Camphor Resistance (CrcB)	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
DTH2_k127_6369477_25	1131812.JQMS01000001_gene2770	2.488e-62	220.0	COG0671@1|root,COG0671@2|Bacteria,4NQ5M@976|Bacteroidetes,1IJ0W@117743|Flavobacteriia,2NW53@237|Flavobacterium	976|Bacteroidetes	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DTH2_k127_6369477_34	926559.JoomaDRAFT_2315	1.464e-45	171.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1I2B3@117743|Flavobacteriia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DTH2_k127_6369477_7	929556.Solca_2782	4.132e-156	498.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DTH2_k127_6369477_20	714943.Mucpa_4494	2.657e-76	268.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
DTH2_k127_6369477_26	484018.BACPLE_00359	3.18e-62	218.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,2FN5J@200643|Bacteroidia,4AMC7@815|Bacteroidaceae	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DTH2_k127_6369477_21	886379.AEWI01000047_gene3069	2.049e-73	250.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia,3XJPD@558415|Marinilabiliaceae	976|Bacteroidetes	F	AIR carboxylase	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DTH2_k127_6369477_31	926562.Oweho_1820	4.6e-53	199.0	COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,1IBFS@117743|Flavobacteriia,2PB2U@246874|Cryomorphaceae	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6369477_6	755732.Fluta_0535	6.133e-174	571.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1I7MT@117743|Flavobacteriia,2PAFS@246874|Cryomorphaceae	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
DTH2_k127_6369477_37	1356852.N008_15650	1.744e-21	111.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEVC@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6369477_22	459349.CLOAM0192	7.524e-69	261.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	Autotransporter,FlgD_ig,PKD
DTH2_k127_6369477_8	755732.Fluta_3314	1.332e-150	505.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF11,fn3
DTH2_k127_6369477_10	1237149.C900_01857	2.039e-141	462.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
DTH2_k127_6369477_15	468059.AUHA01000004_gene2385	5.218e-113	379.0	COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,1IQJK@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
DTH2_k127_6369477_16	1286632.P278_12890	3.285e-111	370.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH2_k127_6369477_9	1346330.M472_21085	4.335e-144	466.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DTH2_k127_6369477_27	491205.JARQ01000003_gene2070	7.291e-61	218.0	2DNNM@1|root,32YAS@2|Bacteria,4NVE7@976|Bacteroidetes,1IA2U@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6369477_13	491205.JARQ01000003_gene2069	1.332e-132	432.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia,3ZQHB@59732|Chryseobacterium	976|Bacteroidetes	P	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
DTH2_k127_6369477_3	755732.Fluta_2821	9.421e-193	610.0	2DBBI@1|root,2Z888@2|Bacteria,4NQB6@976|Bacteroidetes,1I62S@117743|Flavobacteriia	976|Bacteroidetes	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
DTH2_k127_6369477_23	755732.Fluta_1284	2.054e-65	242.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_6369477_33	221109.22778197	1.805e-52	205.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HA85@91061|Bacilli	91061|Bacilli	M	Spore Coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
DTH2_k127_6369477_38	984262.SGRA_0038	1.046e-17	89.0	2EWYR@1|root,346M6@2|Bacteria,4P5DU@976|Bacteroidetes,1IZAP@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
DTH2_k127_6369477_24	929556.Solca_3987	1.077e-62	218.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_6428754_6	1150600.ADIARSV_2539	6.672e-65	239.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_6428754_3	983544.Lacal_2622	1.239e-101	336.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia	976|Bacteroidetes	L	TIGRFAM TIGR02757 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
DTH2_k127_6428754_5	313606.M23134_04812	7.304e-84	290.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
DTH2_k127_6428754_12	1123278.KB893499_gene356	6.308e-06	52.0	2EHJH@1|root,33BBD@2|Bacteria,4NXG2@976|Bacteroidetes,47SY6@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6428754_11	313606.M23134_04813	1.222e-09	59.0	2EHJH@1|root,336RS@2|Bacteria,4NX01@976|Bacteroidetes,47SDR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6428754_10	313606.M23134_04813	1.475e-17	84.0	2EHJH@1|root,336RS@2|Bacteria,4NX01@976|Bacteroidetes,47SDR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6428754_4	269798.CHU_0076	1.493e-101	347.0	COG1807@1|root,COG1807@2|Bacteria,4NP7Y@976|Bacteroidetes,47UYH@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6428754_2	1356852.N008_05910	7.502e-116	386.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,47M1S@768503|Cytophagia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DTH2_k127_6428754_9	1341155.FSS13T_06690	6.69e-20	95.0	COG3212@1|root,COG3212@2|Bacteria,4P9DA@976|Bacteroidetes,1IEN1@117743|Flavobacteriia,2NY22@237|Flavobacterium	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
DTH2_k127_6428754_0	714943.Mucpa_3877	0.0	1263.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1IPYI@117747|Sphingobacteriia	976|Bacteroidetes	O	with chaperone activity ATP-binding subunit	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DTH2_k127_6428754_1	468059.AUHA01000003_gene1843	0.0	1237.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IQJH@117747|Sphingobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DTH2_k127_6428754_8	929556.Solca_1438	1.056e-46	185.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1IRZE@117747|Sphingobacteriia	976|Bacteroidetes	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
DTH2_k127_6428754_7	1124780.ANNU01000051_gene2093	4.205e-55	202.0	COG4123@1|root,COG4123@2|Bacteria,4NQKD@976|Bacteroidetes,47RIZ@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH2_k127_6436121_8	1121104.AQXH01000001_gene1193	1.719e-77	268.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH2_k127_6436121_6	411901.BACCAC_02317	4.542e-93	312.0	COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,2FP00@200643|Bacteroidia,4AMGH@815|Bacteroidaceae	976|Bacteroidetes	P	3'(2'),5'-bisphosphate nucleotidase	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
DTH2_k127_6436121_0	1356852.N008_03945	1.501e-179	567.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,47K8D@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_6436121_1	485918.Cpin_1091	3.533e-171	540.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1IQ44@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH2_k127_6436121_2	153721.MYP_1295	1.566e-107	368.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47NKW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6436121_4	1408433.JHXV01000001_gene703	6.902e-100	337.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PC5X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
DTH2_k127_6436121_3	929556.Solca_4329	9.263e-103	354.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6436121_7	643867.Ftrac_3695	1.343e-86	295.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DTH2_k127_6436121_9	269798.CHU_2203	5.735e-47	175.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,47NS2@768503|Cytophagia	976|Bacteroidetes	C	PFAM cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_6436121_5	1453500.AT05_02900	4.148e-93	311.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_6436121_10	755732.Fluta_1918	1.513e-23	106.0	COG5605@1|root,COG5605@2|Bacteria,4P9DD@976|Bacteroidetes,1IC4B@117743|Flavobacteriia,2PB81@246874|Cryomorphaceae	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
DTH2_k127_6491481_4	1158338.JNLJ01000001_gene867	1.711e-28	119.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_6491481_3	700598.Niako_5570	1.347e-48	190.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
DTH2_k127_6491481_1	700598.Niako_5569	3.512e-107	352.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,1IPVR@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG1134 ABC-type polysaccharide polyol phosphate transport system, ATPase component	-	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran,Wzt_C
DTH2_k127_6491481_2	700598.Niako_5568	3.349e-97	324.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	rgpC	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
DTH2_k127_6491481_0	700598.Niako_5567	9.03e-193	624.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,4NKMR@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
DTH2_k127_6491564_6	929703.KE386491_gene695	5.061e-122	392.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_6491564_9	1124780.ANNU01000005_gene2420	7.54e-98	321.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,47NXE@768503|Cytophagia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
DTH2_k127_6491564_4	1124780.ANNU01000036_gene70	3.423e-155	496.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH2_k127_6491564_0	926549.KI421517_gene841	8.075e-211	661.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,47JKM@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH2_k127_6491564_1	762903.Pedsa_3848	6.474e-194	608.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,1IPRN@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_6491564_5	313606.M23134_05645	2.215e-129	422.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,47M4Q@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.7	ko:K02473	ko00520,ko01100,map00520,map01100	-	R00418	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_6491564_12	1121373.KB903620_gene2044	5.835e-74	256.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,47PBY@768503|Cytophagia	976|Bacteroidetes	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
DTH2_k127_6491564_11	509635.N824_26605	1.448e-76	265.0	COG3823@1|root,COG3823@2|Bacteria,4P2CR@976|Bacteroidetes,1IXIA@117747|Sphingobacteriia	976|Bacteroidetes	O	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
DTH2_k127_6491564_2	1168034.FH5T_09635	2.734e-186	588.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_6491564_10	929556.Solca_0901	2.265e-83	287.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1IQTS@117747|Sphingobacteriia	976|Bacteroidetes	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
DTH2_k127_6491564_8	471854.Dfer_4966	2.335e-116	389.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia	976|Bacteroidetes	CP	COGs COG1668 ABC-type Na efflux pump permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_6491564_7	1168034.FH5T_05190	5.823e-119	389.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,2FMK3@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DTH2_k127_6491564_3	1229276.DI53_3348	1.586e-159	511.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH2_k127_6491564_13	761193.Runsl_3072	8.02e-51	185.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,47QCT@768503|Cytophagia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH2_k127_6504648_3	641526.ADIWIN_0133	5.581e-41	154.0	COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,1I0U6@117743|Flavobacteriia	976|Bacteroidetes	H	Acetyltransferase (Isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_6504648_1	858215.Thexy_1873	2.839e-73	253.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,24G5I@186801|Clostridia,42G13@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM acylneuraminate cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
DTH2_k127_6504648_0	755732.Fluta_2181	4.275e-106	354.0	COG1208@1|root,COG2905@1|root,COG1208@2|Bacteria,COG2905@2|Bacteria,4NFDB@976|Bacteroidetes,1IIX7@117743|Flavobacteriia,2PBTK@246874|Cryomorphaceae	976|Bacteroidetes	M	Nucleotidyl transferase	gmhB	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
DTH2_k127_6504648_2	313606.M23134_02011	4.931e-64	225.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,47RT7@768503|Cytophagia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
DTH2_k127_6504648_4	700598.Niako_2785	2.704e-20	104.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_6513331_0	1131812.JQMS01000001_gene40	0.0	1125.0	COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium	976|Bacteroidetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DTH2_k127_6513331_7	1454007.JAUG01000126_gene340	2.72e-131	431.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DTH2_k127_6513331_3	1356852.N008_16460	5.545e-248	785.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,47YHC@768503|Cytophagia	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH2_k127_6513331_9	1168034.FH5T_03220	8.649e-116	392.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,2FNT5@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_6513331_19	1408433.JHXV01000004_gene3392	1.452e-26	120.0	298K1@1|root,32FY8@2|Bacteria,4PK0P@976|Bacteroidetes,1ICRH@117743|Flavobacteriia,2PBW9@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6513331_5	929703.KE386491_gene1888	1.856e-173	550.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,47KX3@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DTH2_k127_6513331_17	926562.Oweho_0135	3.787e-40	159.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia,2PB39@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_6513331_6	1168034.FH5T_09110	2.62e-139	453.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,2FQFD@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_6513331_2	1356852.N008_16255	4.416e-258	808.0	COG1164@1|root,COG1164@2|Bacteria,4NJFW@976|Bacteroidetes,47TFT@768503|Cytophagia	976|Bacteroidetes	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
DTH2_k127_6513331_18	153721.MYP_2916	3.53e-31	129.0	2DVQJ@1|root,32UZZ@2|Bacteria,4P9HJ@976|Bacteroidetes,47RBJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6513331_13	1121904.ARBP01000006_gene4023	1.136e-56	210.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,47V2Z@768503|Cytophagia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_6513331_11	1086011.HJ01_02178	1.094e-100	339.0	COG4335@1|root,COG4335@2|Bacteria,4NH5H@976|Bacteroidetes,1HXE5@117743|Flavobacteriia,2NSRG@237|Flavobacterium	976|Bacteroidetes	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation,HEAT
DTH2_k127_6513331_8	153721.MYP_3669	1.75e-128	422.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH2_k127_6513331_10	755732.Fluta_2871	9.824e-101	331.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_6513331_1	755732.Fluta_1358	2.049e-266	826.0	COG0753@1|root,COG0753@2|Bacteria,4NFQX@976|Bacteroidetes,1HWVN@117743|Flavobacteriia,2PAHW@246874|Cryomorphaceae	976|Bacteroidetes	C	Catalase	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
DTH2_k127_6513331_23	313603.FB2170_17341	2.114e-15	77.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia,2PHTD@252356|Maribacter	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH2_k127_6513331_4	755732.Fluta_2869	2.976e-220	690.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia,2PA7E@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
DTH2_k127_6513331_21	929562.Emtol_0588	1.888e-23	100.0	COG0607@1|root,COG0607@2|Bacteria,4PA45@976|Bacteroidetes,47SQ5@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6513331_16	641524.ADICYQ_3985	2.494e-40	151.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47SAY@768503|Cytophagia	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_6513331_14	1131812.JQMS01000001_gene42	1.627e-49	178.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia,2NX6I@237|Flavobacterium	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_6513331_22	1121373.KB903625_gene3213	1.168e-20	93.0	2E60B@1|root,330PR@2|Bacteria,4NXSG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6513331_12	929562.Emtol_0584	1.078e-66	229.0	COG1764@1|root,COG1764@2|Bacteria,4P9T2@976|Bacteroidetes,47S0N@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DTH2_k127_6513331_15	743722.Sph21_3201	3.411e-43	159.0	COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes	976|Bacteroidetes	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH2_k127_6513331_20	755732.Fluta_3016	2.731e-24	104.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,1I34F@117743|Flavobacteriia,2PBX8@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
DTH2_k127_6515145_6	1123248.KB893316_gene4551	2.454e-94	313.0	COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1IW2E@117747|Sphingobacteriia	976|Bacteroidetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH2_k127_6515145_4	694427.Palpr_1159	5.272e-119	387.0	COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,2FNY2@200643|Bacteroidia,22WRH@171551|Porphyromonadaceae	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH2_k127_6515145_7	1123248.KB893316_gene4553	5.462e-78	265.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,1INTS@117747|Sphingobacteriia	976|Bacteroidetes	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
DTH2_k127_6515145_8	1408433.JHXV01000010_gene535	8.685e-34	137.0	2AAU0@1|root,30Y70@2|Bacteria,4PBYC@976|Bacteroidetes,1ICQX@117743|Flavobacteriia,2PBTU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6515145_9	869213.JCM21142_461	2.763e-21	97.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,47R7M@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_6515145_5	1121889.AUDM01000010_gene584	4.012e-97	332.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2P0BI@237|Flavobacterium	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
DTH2_k127_6515145_3	1408473.JHXO01000010_gene3516	2.258e-126	409.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,2FN64@200643|Bacteroidia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
DTH2_k127_6515145_1	926562.Oweho_2840	1.235e-192	610.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia,2PAKT@246874|Cryomorphaceae	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
DTH2_k127_6515145_0	1267211.KI669560_gene1104	8.834e-237	736.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DTH2_k127_6515145_2	1121899.Q764_12270	3.212e-184	580.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1HX3E@117743|Flavobacteriia,2NS9C@237|Flavobacterium	976|Bacteroidetes	O	Metalloendopeptidase	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
DTH2_k127_6516287_0	1313421.JHBV01000019_gene5329	1.464e-134	475.0	COG2132@1|root,COG4935@1|root,COG2132@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,SprB
DTH2_k127_6516287_1	1408433.JHXV01000033_gene1176	6.118e-42	179.0	COG3291@1|root,COG3291@2|Bacteria,4NRDH@976|Bacteroidetes,1IIK5@117743|Flavobacteriia	976|Bacteroidetes	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6516287_2	755732.Fluta_1672	4.445e-37	153.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_6520480_5	1237149.C900_05060	0.0008668	42.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,47MP4@768503|Cytophagia	976|Bacteroidetes	D	PFAM ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DTH2_k127_6520480_2	1122931.AUAE01000032_gene3000	2.557e-103	348.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
DTH2_k127_6520480_1	694427.Palpr_1191	2.953e-114	379.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,2FSCQ@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_6520480_0	485918.Cpin_6574	1.512e-136	442.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
DTH2_k127_6520480_3	762903.Pedsa_2925	1.25e-50	185.0	COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,1ISTP@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DTH2_k127_6520480_4	468059.AUHA01000006_gene2884	1.074e-11	64.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,1INVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
DTH2_k127_6539481_7	1218103.CIN01S_04_05090	1.765e-25	109.0	COG1524@1|root,COG1524@2|Bacteria,4PKSD@976|Bacteroidetes,1IJEH@117743|Flavobacteriia,3ZTJD@59732|Chryseobacterium	976|Bacteroidetes	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
DTH2_k127_6539481_4	1168034.FH5T_02685	4.065e-46	180.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,2FMM1@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
DTH2_k127_6539481_0	714943.Mucpa_4144	3.016e-226	719.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_6539481_8	1313421.JHBV01000032_gene1589	6.79e-08	65.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes	976|Bacteroidetes	DZ	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_6539481_3	485918.Cpin_1064	2.315e-148	477.0	COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1IQTZ@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH2_k127_6539481_5	1313301.AUGC01000003_gene2119	3.074e-42	164.0	COG1266@1|root,COG1266@2|Bacteria,4P5RH@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DTH2_k127_6539481_6	1185876.BN8_04943	5.021e-36	142.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,47QDF@768503|Cytophagia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
DTH2_k127_6539481_2	762903.Pedsa_1051	1.383e-148	478.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IVKE@117747|Sphingobacteriia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_6539481_1	1250278.JQNQ01000001_gene3619	4.503e-220	694.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,1HWX1@117743|Flavobacteriia	976|Bacteroidetes	L	type III restriction enzyme, res subunit	res	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
DTH2_k127_6545802_9	755732.Fluta_0918	8.855e-10	67.0	COG3210@1|root,COG3210@2|Bacteria,4P1PQ@976|Bacteroidetes,1ICP0@117743|Flavobacteriia,2PBF7@246874|Cryomorphaceae	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6545802_1	269798.CHU_0862	3.983e-141	459.0	COG1232@1|root,COG1232@2|Bacteria,4NKQR@976|Bacteroidetes	976|Bacteroidetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
DTH2_k127_6545802_4	1227739.Hsw_0776	3.208e-59	216.0	28PB0@1|root,2ZC40@2|Bacteria,4NN1W@976|Bacteroidetes,47PEE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6545802_2	760192.Halhy_1525	8.95e-117	384.0	COG4447@1|root,COG4447@2|Bacteria,4NGUK@976|Bacteroidetes,1IS3N@117747|Sphingobacteriia	976|Bacteroidetes	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
DTH2_k127_6545802_0	1121895.Q765_18985	3.727e-272	850.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia,2NTGW@237|Flavobacterium	976|Bacteroidetes	EU	Peptidase S9	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
DTH2_k127_6545802_8	1453498.LG45_00925	7.267e-11	75.0	COG3420@1|root,COG3420@2|Bacteria,4PJ27@976|Bacteroidetes,1IDUT@117743|Flavobacteriia,2NZ9E@237|Flavobacterium	976|Bacteroidetes	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6545802_7	1131812.JQMS01000001_gene985	3.659e-13	83.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1I414@117743|Flavobacteriia,2NX6N@237|Flavobacterium	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
DTH2_k127_6545802_6	700598.Niako_0091	6.552e-21	96.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
DTH2_k127_6545802_10	742766.HMPREF9455_01157	0.0003189	51.0	2EPC9@1|root,33GZ0@2|Bacteria,4NYM1@976|Bacteroidetes,2FY7I@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6545802_3	261292.Nit79A3_3094	6.778e-93	312.0	COG1266@1|root,COG1266@2|Bacteria,1R5BW@1224|Proteobacteria,2W2E1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DTH2_k127_6545802_5	1090319.KE386571_gene817	5.495e-24	108.0	COG3685@1|root,COG3685@2|Bacteria,1REKN@1224|Proteobacteria,2U73U@28211|Alphaproteobacteria,2K47D@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
DTH2_k127_6551329_11	927658.AJUM01000034_gene421	3.792e-59	216.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,2FQ0B@200643|Bacteroidia,3XJ93@558415|Marinilabiliaceae	976|Bacteroidetes	S	Gliding motility-associated protein GldN	gldN	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6551329_10	1121904.ARBP01000004_gene849	3.548e-61	217.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
DTH2_k127_6551329_8	1121129.KB903373_gene481	6.074e-70	250.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia,22X4Y@171551|Porphyromonadaceae	976|Bacteroidetes	S	Permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_6551329_7	1121904.ARBP01000005_gene4721	2.211e-77	270.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,47N57@768503|Cytophagia	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
DTH2_k127_6551329_9	1189620.AJXL01000164_gene2144	1.92e-62	221.0	COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,1I18P@117743|Flavobacteriia,2NVI0@237|Flavobacterium	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
DTH2_k127_6551329_12	1185876.BN8_05067	3.823e-29	120.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,47RHB@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
DTH2_k127_6551329_0	1158294.JOMI01000007_gene489	1.484e-211	675.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,2FMY5@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH2_k127_6551329_5	1121904.ARBP01000009_gene4301	2.219e-96	325.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,47MCF@768503|Cytophagia	976|Bacteroidetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
DTH2_k127_6551329_4	485918.Cpin_1817	4.906e-133	429.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1IQIJ@117747|Sphingobacteriia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
DTH2_k127_6551329_1	485918.Cpin_1818	1.252e-179	571.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1IQWR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DTH2_k127_6551329_3	1408813.AYMG01000010_gene483	8.634e-145	466.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1IQ0J@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_6551329_2	1121912.AUHD01000013_gene945	3.372e-174	552.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
DTH2_k127_6551329_6	694427.Palpr_1300	4.305e-84	282.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,2FPAY@200643|Bacteroidia,22XFN@171551|Porphyromonadaceae	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_6552224_4	1408433.JHXV01000017_gene1597	3.018e-26	112.0	2C52N@1|root,315JU@2|Bacteria,4PJRQ@976|Bacteroidetes,1IE9T@117743|Flavobacteriia,2PB34@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_6552224_0	376686.Fjoh_0279	1.701e-200	637.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1HXK1@117743|Flavobacteriia,2NT48@237|Flavobacterium	976|Bacteroidetes	S	FAD-binding protein	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
DTH2_k127_6552224_3	643867.Ftrac_0748	1.58e-32	131.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia	976|Bacteroidetes	S	PFAM Membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DTH2_k127_6552224_1	926561.KB900622_gene703	1.055e-91	308.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,3WBRI@53433|Halanaerobiales	186801|Clostridia	S	Ribosomal protein S1-like RNA-binding domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
DTH2_k127_6552224_6	1296416.JACB01000003_gene791	4.13e-05	53.0	COG3227@1|root,COG3291@1|root,COG4447@1|root,COG5184@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2YJ7Y@290174|Aquimarina	976|Bacteroidetes	DEZ	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,PA,TSP_3,fn3
DTH2_k127_6552224_2	1250232.JQNJ01000001_gene3685	1.02e-61	217.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,1I1AB@117743|Flavobacteriia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
DTH2_k127_6552224_5	700598.Niako_6864	2.184e-23	104.0	2E4AG@1|root,33IJ2@2|Bacteria,4P9RI@976|Bacteroidetes,1IUJQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
DTH2_k127_6615279_4	755732.Fluta_1112	4.49e-15	80.0	2CFX6@1|root,32S2Q@2|Bacteria,4NTW8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6615279_0	471854.Dfer_5799	6.089e-159	506.0	COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,47KBX@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
DTH2_k127_6615279_2	1121481.AUAS01000012_gene267	4.982e-51	183.0	2CE7N@1|root,30Q80@2|Bacteria,4NNKP@976|Bacteroidetes,47RMH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6615279_3	1313421.JHBV01000012_gene4087	1.046e-48	184.0	28IKZ@1|root,2Z8MJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1702)	-	-	-	ko:K21161	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	DUF1702
DTH2_k127_6615279_1	1313421.JHBV01000012_gene4088	1.436e-132	433.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,Trp_halogenase
DTH2_k127_6663004_2	153721.MYP_3416	5.757e-34	142.0	COG3209@1|root,COG3291@1|root,COG5184@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,4PKPC@976|Bacteroidetes,47N8S@768503|Cytophagia	976|Bacteroidetes	DZ	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,RCC1
DTH2_k127_6663004_1	929556.Solca_0773	4.659e-44	173.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,1ISEP@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_6663004_0	1120965.AUBV01000008_gene2053	2.561e-60	216.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,47NW3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
DTH2_k127_6701958_1	927658.AJUM01000037_gene2297	2.046e-105	361.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,2G0DG@200643|Bacteroidia,3XJHT@558415|Marinilabiliaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_6701958_2	29581.BW37_04444	8.881e-07	55.0	2AD7J@1|root,312WH@2|Bacteria,1RHF8@1224|Proteobacteria,2VRJG@28216|Betaproteobacteria,474M1@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_6701958_0	755732.Fluta_1225	3.552e-287	912.0	COG3023@1|root,COG3023@2|Bacteria,4NN1U@976|Bacteroidetes	976|Bacteroidetes	V	COGs COG3023 Negative regulator of beta-lactamase expression	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CUB
DTH2_k127_670589_6	929562.Emtol_2898	4.191e-79	268.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
DTH2_k127_670589_7	153721.MYP_3414	1.699e-66	245.0	COG3509@1|root,COG3509@2|Bacteria,4PKPB@976|Bacteroidetes	976|Bacteroidetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_670589_4	1121373.KB903662_gene12	1.707e-125	407.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,47MB5@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
DTH2_k127_670589_0	1122225.AULQ01000001_gene1500	3.161e-215	677.0	COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,1HXVA@117743|Flavobacteriia	976|Bacteroidetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
DTH2_k127_670589_8	1267211.KI669560_gene1791	1.9e-58	205.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
DTH2_k127_670589_5	929556.Solca_2398	1.638e-119	392.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DTH2_k127_670589_3	929556.Solca_4177	1.053e-134	432.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_670589_9	313594.PI23P_09340	3.245e-55	197.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia,3VWJ5@52959|Polaribacter	976|Bacteroidetes	V	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
DTH2_k127_670589_2	468059.AUHA01000002_gene74	3.266e-164	552.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH2_k127_670589_10	1168034.FH5T_01875	6.071e-39	151.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,2FTAK@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG14473 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_670589_1	468059.AUHA01000006_gene2884	6.255e-202	642.0	COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,1INVA@117747|Sphingobacteriia	976|Bacteroidetes	E	Oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
DTH2_k127_6717787_0	926562.Oweho_3351	7.6e-264	855.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,1I791@117743|Flavobacteriia,2PA5S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_674260_4	1250005.PHEL85_2764	2.506e-92	312.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,1HZYF@117743|Flavobacteriia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
DTH2_k127_674260_6	1313421.JHBV01000042_gene3343	1.81e-72	260.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_674260_3	1408813.AYMG01000010_gene619	1.125e-103	345.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1IPJH@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
DTH2_k127_674260_11	714943.Mucpa_1655	5.765e-29	124.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
DTH2_k127_674260_0	929556.Solca_0498	6.085e-217	682.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
DTH2_k127_674260_10	1107311.Q767_10385	2.04e-41	157.0	COG2030@1|root,COG2030@2|Bacteria,4PPGX@976|Bacteroidetes,1IKMM@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
DTH2_k127_674260_8	1121912.AUHD01000001_gene2517	4.314e-68	235.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,1HZTW@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
DTH2_k127_674260_2	1121904.ARBP01000003_gene6488	1.749e-131	426.0	COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,47NHC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH2_k127_674260_1	1189620.AJXL01000006_gene2411	1.688e-142	455.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia,2NSPM@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
DTH2_k127_674260_9	1008457.BAEX01000061_gene304	8.305e-53	189.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1I2XJ@117743|Flavobacteriia,47I6Y@76831|Myroides	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DTH2_k127_674260_5	1122225.AULQ01000007_gene2366	2.849e-75	257.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DTH2_k127_674260_12	1122176.KB903554_gene3803	5.132e-15	82.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	LysM,TPR_16,TPR_6,YfiO
DTH2_k127_674260_7	313590.MED134_03354	1.42e-70	249.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia,37EFF@326319|Dokdonia	976|Bacteroidetes	S	DisA bacterial checkpoint controller nucleotide-binding	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
DTH2_k127_6763607_0	755732.Fluta_1284	1.955e-95	326.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_6763607_4	1235457.C404_03565	3.572e-18	91.0	28WUQ@1|root,2ZIU4@2|Bacteria,1P7TM@1224|Proteobacteria,2W7CR@28216|Betaproteobacteria,1KEBR@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6763607_3	313603.FB2170_13011	1.952e-25	106.0	2E63Z@1|root,330SZ@2|Bacteria,4NVTW@976|Bacteroidetes,1I540@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6763607_1	755732.Fluta_3847	1.788e-84	304.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
DTH2_k127_6763607_2	1345695.CLSA_c24570	2.164e-39	162.0	COG4412@1|root,COG4412@2|Bacteria,1UIJ6@1239|Firmicutes,24BZI@186801|Clostridia,36HGY@31979|Clostridiaceae	186801|Clostridia	G	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CW_binding_1,F5_F8_type_C,Laminin_G_3
DTH2_k127_677295_0	1408433.JHXV01000004_gene3393	4.343e-173	577.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_6803255_4	1484460.JSWG01000012_gene1490	1.415e-124	404.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,1HXCF@117743|Flavobacteriia	976|Bacteroidetes	I	dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DTH2_k127_6803255_11	1124780.ANNU01000019_gene1754	2.7e-79	272.0	COG3186@1|root,COG3186@2|Bacteria,4NEX5@976|Bacteroidetes,47KWF@768503|Cytophagia	976|Bacteroidetes	E	PFAM Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
DTH2_k127_6803255_13	926562.Oweho_2251	7.391e-44	163.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1I2P9@117743|Flavobacteriia,2PB1D@246874|Cryomorphaceae	976|Bacteroidetes	Q	Thioesterase superfamily	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
DTH2_k127_6803255_1	983544.Lacal_1617	4.06e-190	600.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1HWZU@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the thiolase family	pcaF	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_6803255_8	1313421.JHBV01000036_gene2453	3.819e-93	309.0	COG0663@1|root,COG0663@2|Bacteria,4NG5P@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial transferase hexapeptide repeat	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
DTH2_k127_6803255_20	1250006.JHZZ01000001_gene1813	6.702e-19	92.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia,3VV85@52959|Polaribacter	976|Bacteroidetes	C	Hydroxymethylglutaryl-coenzyme A reductase	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
DTH2_k127_6803255_0	153721.MYP_4507	0.0	1331.0	COG2373@1|root,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,47K94@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_comp,A2M_recep,CarbopepD_reg_2,Plug,Thiol-ester_cl
DTH2_k127_6803255_18	1185876.BN8_01631	6.809e-27	110.0	COG4628@1|root,COG4628@2|Bacteria,4NUS1@976|Bacteroidetes,47RWW@768503|Cytophagia	976|Bacteroidetes	S	conserved protein (DUF2132)	-	-	-	-	-	-	-	-	-	-	-	-	VF530
DTH2_k127_6803255_2	1349785.BAUG01000013_gene1028	2.95e-158	511.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HZ6Y@117743|Flavobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DTH2_k127_6803255_9	929556.Solca_0521	1.78e-86	294.0	COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,1IR4D@117747|Sphingobacteriia	976|Bacteroidetes	N	OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
DTH2_k127_6803255_5	1185876.BN8_05437	5.478e-121	400.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,47KMP@768503|Cytophagia	976|Bacteroidetes	E	PFAM Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DTH2_k127_6803255_19	709991.Odosp_2706	5.693e-25	114.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,2FSG2@200643|Bacteroidia,22ZWE@171551|Porphyromonadaceae	976|Bacteroidetes	K	Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_6803255_3	1341181.FLJC2902T_06210	2.299e-149	484.0	COG3278@1|root,COG3278@2|Bacteria,4NIGA@976|Bacteroidetes,1HZJ7@117743|Flavobacteriia,2NUZA@237|Flavobacterium	976|Bacteroidetes	O	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
DTH2_k127_6803255_17	1267211.KI669560_gene2189	1.864e-29	121.0	COG2010@1|root,COG2010@2|Bacteria,4NQE3@976|Bacteroidetes,1IU8D@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrome_CBB3
DTH2_k127_6803255_14	1122605.KB893627_gene2964	1.524e-41	162.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_6803255_7	1123248.KB893314_gene3278	1.82e-96	329.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1IR9R@117747|Sphingobacteriia	976|Bacteroidetes	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DTH2_k127_6803255_16	1123376.AUIU01000015_gene358	5.032e-35	138.0	COG2005@1|root,COG2005@2|Bacteria	2|Bacteria	P	Transcriptional regulator	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1
DTH2_k127_6803255_15	1408433.JHXV01000001_gene737	1.467e-35	142.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DTH2_k127_6803255_22	1492737.FEM08_07540	6.39e-08	57.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DTH2_k127_6803255_6	1178825.ALIH01000002_gene942	8.101e-100	337.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia	976|Bacteroidetes	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
DTH2_k127_6803255_12	1121875.KB907550_gene642	7.439e-62	215.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
DTH2_k127_6803255_10	1124780.ANNU01000013_gene3830	5.554e-83	278.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,47M7C@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
DTH2_k127_6830062_0	313606.M23134_02237	6.414e-191	625.0	COG3209@1|root,COG3291@1|root,COG3386@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,4NJ9V@976|Bacteroidetes,47N8F@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6830062_5	1121373.KB903643_gene3411	4.647e-15	90.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	ASH,CHU_C,DUF1573,Laminin_G_3,PKD
DTH2_k127_6830062_3	1454007.JAUG01000055_gene3324	3.333e-59	216.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1IP9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_6830062_4	869213.JCM21142_282	3.422e-53	212.0	COG0823@1|root,COG3291@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,4P0F7@976|Bacteroidetes	976|Bacteroidetes	U	Cell envelope biogenesis protein OmpA	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_6830062_1	1121904.ARBP01000002_gene6732	1.99e-104	348.0	COG3291@1|root,COG3291@2|Bacteria,4NHJJ@976|Bacteroidetes,47U4K@768503|Cytophagia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6830062_2	1121904.ARBP01000026_gene641	1.496e-66	247.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_6841757_3	1121930.AQXG01000003_gene2748	3.083e-28	118.0	COG3920@1|root,COG5002@1|root,COG3920@2|Bacteria,COG5002@2|Bacteria,4NINT@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2,PAS_3,PAS_9
DTH2_k127_6841757_1	468059.AUHA01000006_gene3046	9.935e-161	514.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH2_k127_6841757_0	1454007.JAUG01000027_gene2784	1.353e-219	689.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1IP3X@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_6841757_2	1122621.ATZA01000010_gene208	4.813e-139	456.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
DTH2_k127_6841757_4	485917.Phep_4158	2.319e-22	97.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IPYS@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM (2R)-phospho-3-sulfolactate synthase ComA	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
DTH2_k127_6863356_0	755732.Fluta_0918	2.158e-150	518.0	COG3210@1|root,COG3210@2|Bacteria,4P1PQ@976|Bacteroidetes,1ICP0@117743|Flavobacteriia,2PBF7@246874|Cryomorphaceae	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6863356_2	643867.Ftrac_1237	2.855e-83	302.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_6863356_1	1185876.BN8_02873	9.304e-100	357.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_6863356_3	1408433.JHXV01000028_gene2134	4.658e-73	256.0	COG3064@1|root,COG3064@2|Bacteria,4PKYH@976|Bacteroidetes,1IJHH@117743|Flavobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_6863356_9	745718.JADT01000018_gene653	1.751e-15	84.0	COG4733@1|root,COG5644@1|root,COG4733@2|Bacteria,COG5644@2|Bacteria,4NYKY@976|Bacteroidetes,1IIIZ@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_6863356_4	1121889.AUDM01000002_gene448	1.672e-45	190.0	COG3210@1|root,COG4675@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_6863356_11	1341181.FLJC2902T_22140	6.058e-11	77.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1IKUQ@117743|Flavobacteriia,2NXWT@237|Flavobacterium	976|Bacteroidetes	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Peptidase_S74
DTH2_k127_6863356_7	1408813.AYMG01000030_gene676	1.974e-31	144.0	COG3210@1|root,COG4675@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria,4NHCC@976|Bacteroidetes,1J0QK@117747|Sphingobacteriia	976|Bacteroidetes	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
DTH2_k127_6863356_10	1270193.JARP01000001_gene3008	1.906e-14	88.0	COG5295@1|root,COG5295@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia,2NUIA@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6863356_6	1408813.AYMG01000030_gene676	2.922e-40	173.0	COG3210@1|root,COG4675@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria,4NHCC@976|Bacteroidetes,1J0QK@117747|Sphingobacteriia	976|Bacteroidetes	UW	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
DTH2_k127_6863356_8	153721.MYP_3416	4.518e-27	129.0	COG3209@1|root,COG3291@1|root,COG5184@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,4PKPC@976|Bacteroidetes,47N8S@768503|Cytophagia	976|Bacteroidetes	DZ	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,RCC1
DTH2_k127_6863356_5	869213.JCM21142_31278	3.414e-41	155.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_6920436_0	1484460.JSWG01000001_gene2152	1.059e-152	494.0	COG2271@1|root,COG2271@2|Bacteria,4NK2M@976|Bacteroidetes,1I107@117743|Flavobacteriia	976|Bacteroidetes	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_6920436_5	411154.GFO_0980	2.343e-33	132.0	COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6920436_4	411154.GFO_0980	2.158e-35	138.0	COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6920436_1	313595.P700755_001169	6.907e-72	247.0	COG4319@1|root,COG4319@2|Bacteria,4NYPP@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_6920436_6	1129374.AJE_16454	1.277e-06	57.0	2CD3D@1|root,32RWZ@2|Bacteria,1N61G@1224|Proteobacteria,1SB8Q@1236|Gammaproteobacteria,46BJ4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_6920436_3	1380390.JIAT01000010_gene4968	2.06e-37	144.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
DTH2_k127_6920436_2	1121875.KB907547_gene2948	8.288e-47	168.0	COG0251@1|root,COG0251@2|Bacteria,4NMXE@976|Bacteroidetes,1I1GR@117743|Flavobacteriia	976|Bacteroidetes	J	Translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
DTH2_k127_6922037_6	1144313.PMI10_04031	7.365e-08	63.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,CHU_C,Cadherin_3,Flg_new,LRR_5,Phage_tail_2,SLH
DTH2_k127_6922037_0	1237149.C900_02738	3.66e-218	682.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DTH2_k127_6922037_1	929704.Myrod_2400	8.373e-177	563.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1HWW8@117743|Flavobacteriia,47HUR@76831|Myroides	976|Bacteroidetes	C	e3 binding domain	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_6922037_2	153721.MYP_243	4.825e-132	449.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_6922037_4	1408433.JHXV01000026_gene3026	4.202e-108	381.0	COG0419@1|root,COG0823@1|root,COG0419@2|Bacteria,COG0823@2|Bacteria,4P15I@976|Bacteroidetes,1IE72@117743|Flavobacteriia,2PBDD@246874|Cryomorphaceae	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_6922037_5	153721.MYP_3101	4.553e-102	351.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4P298@976|Bacteroidetes,47TIX@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_6922037_3	929556.Solca_1342	3.268e-127	411.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
DTH2_k127_6939185_2	1341155.FSS13T_22350	2.449e-44	169.0	COG1216@1|root,COG1216@2|Bacteria,4NJ6R@976|Bacteroidetes,1IISN@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_6939185_1	1123057.P872_00840	2.016e-52	198.0	COG0463@1|root,COG0463@2|Bacteria,4PP9W@976|Bacteroidetes,47YJM@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_6939185_0	864073.HFRIS_012469	9.307e-69	244.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_6939185_3	314345.SPV1_07526	1.029e-38	153.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1RD8N@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Glycosyl transferase family 11	-	-	2.4.1.308	ko:K21367	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT11	-	Glyco_transf_11
DTH2_k127_6965960_1	402612.FP0574	8.208e-199	627.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2NSEK@237|Flavobacterium	976|Bacteroidetes	C	Dehydrogenase	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DTH2_k127_6965960_2	1408433.JHXV01000010_gene648	1.057e-70	244.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1IG54@117743|Flavobacteriia,2PBA5@246874|Cryomorphaceae	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
DTH2_k127_6965960_0	755732.Fluta_0516	9.121e-306	958.0	COG0477@1|root,COG1674@1|root,COG0477@2|Bacteria,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia,2PAJ7@246874|Cryomorphaceae	976|Bacteroidetes	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH2_k127_7012392_0	1408433.JHXV01000005_gene2356	1.133e-239	753.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,1HXCJ@117743|Flavobacteriia,2PABT@246874|Cryomorphaceae	976|Bacteroidetes	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
DTH2_k127_7012392_1	1408433.JHXV01000005_gene2360	1.519e-121	402.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
DTH2_k127_7012392_2	1408433.JHXV01000005_gene2361	1.66e-49	182.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_3,Kelch_4,Kelch_6
DTH2_k127_707529_1	1009370.ALO_04473	1.983e-13	79.0	2A2AS@1|root,30QMN@2|Bacteria,1V3QM@1239|Firmicutes,4H4BV@909932|Negativicutes	909932|Negativicutes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
DTH2_k127_707529_0	616991.JPOO01000001_gene2807	3.81e-258	826.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,4PKNJ@976|Bacteroidetes,1IJIK@117743|Flavobacteriia	976|Bacteroidetes	T	protein-glutamate methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_8,PAS_9
DTH2_k127_7079016_18	886377.Murru_2932	1.144e-34	144.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DTH2_k127_7079016_20	269798.CHU_3371	1.822e-31	132.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,47R92@768503|Cytophagia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DTH2_k127_7079016_3	1122176.KB903537_gene1695	2.522e-170	550.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IWP1@117747|Sphingobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_7079016_7	153721.MYP_2040	8.024e-115	374.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47XX0@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_7079016_5	929556.Solca_0221	1.02e-134	444.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_7079016_12	515622.bpr_I0396	5.653e-90	306.0	COG0451@1|root,COG0451@2|Bacteria,1UYD1@1239|Firmicutes,25EZR@186801|Clostridia	186801|Clostridia	GM	GDP-mannose 4,6 dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_7079016_9	1408433.JHXV01000038_gene2219	3.986e-107	361.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1IEBF@117743|Flavobacteriia,2PB0Z@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
DTH2_k127_7079016_8	926549.KI421517_gene3075	6.386e-110	367.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,47KVT@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
DTH2_k127_7079016_2	1250232.JQNJ01000001_gene2353	5.198e-179	571.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,1HXSE@117743|Flavobacteriia	976|Bacteroidetes	EH	Anthranilate synthase	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH2_k127_7079016_13	694427.Palpr_2892	9.999e-82	275.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,2FM5F@200643|Bacteroidia,22XQD@171551|Porphyromonadaceae	976|Bacteroidetes	EH	Glutamine amidotransferase class-I	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_7079016_6	714943.Mucpa_0533	9.577e-130	421.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,1INY5@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
DTH2_k127_7079016_10	1237149.C900_03302	9.003e-103	340.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,47JRX@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
DTH2_k127_7079016_19	1008457.BAEX01000037_gene2360	8.222e-32	130.0	COG0454@1|root,COG0456@2|Bacteria,4NQVT@976|Bacteroidetes,1I3AB@117743|Flavobacteriia,47IBA@76831|Myroides	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DTH2_k127_7079016_14	1107311.Q767_04360	7.702e-61	216.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1I1CD@117743|Flavobacteriia,2NVBQ@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
DTH2_k127_7079016_1	1120951.AUBG01000006_gene498	2.856e-206	646.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH2_k127_7079016_11	1450525.JATV01000006_gene860	5.944e-96	320.0	COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,1HYYA@117743|Flavobacteriia,2NT4T@237|Flavobacterium	976|Bacteroidetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
DTH2_k127_7079016_4	1121957.ATVL01000007_gene2313	7.117e-151	482.0	COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,47KY7@768503|Cytophagia	976|Bacteroidetes	E	PFAM DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
DTH2_k127_7079016_0	984262.SGRA_2537	9.237e-221	722.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes	976|Bacteroidetes	DZ	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_7079016_21	925409.KI911562_gene197	3.113e-13	84.0	COG1404@1|root,COG1404@2|Bacteria,4NFMW@976|Bacteroidetes,1IU7A@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8,fn3
DTH2_k127_7079016_22	1227739.Hsw_3413	1.81e-05	55.0	2EJJG@1|root,33DAE@2|Bacteria,4PPTW@976|Bacteroidetes,47SVD@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7079016_17	1046627.BZARG_1537	2.994e-54	204.0	COG2334@1|root,COG2334@2|Bacteria,4NGVS@976|Bacteroidetes,1HYWD@117743|Flavobacteriia	976|Bacteroidetes	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
DTH2_k127_7079016_16	445961.IW15_09575	2.117e-58	210.0	2BXI0@1|root,2Z9A2@2|Bacteria,4NFDQ@976|Bacteroidetes,1I0GE@117743|Flavobacteriia,3ZP9U@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
DTH2_k127_7079016_23	266748.HY04_07330	0.0004578	51.0	2E78C@1|root,331S1@2|Bacteria,4NPWT@976|Bacteroidetes,1I2MW@117743|Flavobacteriia,3ZUNK@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7079016_15	1123278.KB893387_gene4322	1.172e-58	215.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,47K6N@768503|Cytophagia	976|Bacteroidetes	DZ	Galactose oxidase, central domain	nanM	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
DTH2_k127_7090348_1	929562.Emtol_0583	1.641e-83	284.0	COG0526@1|root,COG0607@1|root,COG0526@2|Bacteria,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47PJB@768503|Cytophagia	976|Bacteroidetes	OP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
DTH2_k127_7090348_0	1356852.N008_04075	1.754e-94	326.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,47M30@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
DTH2_k127_7090348_2	1121859.KB890739_gene2665	1.744e-11	64.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,47K6Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH2_k127_7095886_10	755732.Fluta_3651	4.296e-32	132.0	COG0518@1|root,COG0518@2|Bacteria,4P7ZK@976|Bacteroidetes	976|Bacteroidetes	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DTH2_k127_7095886_1	1358423.N180_02545	1.501e-181	576.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1IP2N@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane protein required for spore maturation in B.subtilis	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
DTH2_k127_7095886_13	756499.Desde_1555	1.417e-07	64.0	COG1807@1|root,COG1807@2|Bacteria,1TVJV@1239|Firmicutes,259MS@186801|Clostridia,263HN@186807|Peptococcaceae	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_7095886_6	869213.JCM21142_73060	6.68e-80	276.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,47WJ6@768503|Cytophagia	976|Bacteroidetes	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	lytG	-	3.2.1.96	ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,LysM
DTH2_k127_7095886_5	1121904.ARBP01000028_gene1643	3.336e-84	288.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
DTH2_k127_7095886_4	1396141.BATP01000059_gene2543	2.297e-101	342.0	COG1858@1|root,COG1858@2|Bacteria,46U0N@74201|Verrucomicrobia,2IUGP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
DTH2_k127_7095886_12	860228.Ccan_20850	3.326e-19	90.0	2E5CT@1|root,3304V@2|Bacteria,4NUT8@976|Bacteroidetes,1I511@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7095886_0	1121129.KB903359_gene2402	0.0	1065.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,2FNQK@200643|Bacteroidia,22X3D@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
DTH2_k127_7095886_8	391598.FBBAL38_10117	1.432e-74	264.0	COG3266@1|root,COG3266@2|Bacteria,4NKYH@976|Bacteroidetes,1I2JU@117743|Flavobacteriia	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7095886_2	1408473.JHXO01000004_gene33	1.216e-144	463.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
DTH2_k127_7095886_7	714943.Mucpa_2855	2.75e-78	268.0	COG0670@1|root,COG0670@2|Bacteria,4NR2U@976|Bacteroidetes,1ISUF@117747|Sphingobacteriia	976|Bacteroidetes	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
DTH2_k127_7095886_3	391596.PBAL39_24445	1.794e-103	339.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
DTH2_k127_7095886_9	1358423.N180_16770	7.374e-60	209.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1ISCG@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydrobiopterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_7095886_11	391596.PBAL39_24435	7.11e-26	111.0	COG0775@1|root,COG0775@2|Bacteria,4NPA7@976|Bacteroidetes,1ISHD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_7103356_4	755732.Fluta_1367	2.926e-29	121.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH2_k127_7103356_2	1121887.AUDK01000008_gene1203	9.54e-69	258.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1ICYX@117743|Flavobacteriia,2NW87@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_7103356_1	1506583.JQJY01000005_gene2361	1.122e-99	335.0	COG0332@1|root,COG0332@2|Bacteria,4NFZK@976|Bacteroidetes,1I1T1@117743|Flavobacteriia,2NUSZ@237|Flavobacterium	976|Bacteroidetes	I	Chalcone and stilbene synthases, N-terminal domain	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_7103356_5	694427.Palpr_1152	3.049e-13	72.0	COG0236@1|root,COG0236@2|Bacteria,4NWWS@976|Bacteroidetes,2FUXS@200643|Bacteroidia,22YS2@171551|Porphyromonadaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH2_k127_7103356_0	1506583.JQJY01000005_gene2364	1.592e-102	345.0	COG0332@1|root,COG0332@2|Bacteria,4NFMX@976|Bacteroidetes,1IIN6@117743|Flavobacteriia,2NV2R@237|Flavobacterium	976|Bacteroidetes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_7103356_3	1506583.JQJY01000005_gene2363	4.187e-59	213.0	COG1028@1|root,COG1028@2|Bacteria,4NN4M@976|Bacteroidetes,1I2D1@117743|Flavobacteriia,2NWU5@237|Flavobacterium	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH2_k127_7103356_6	994573.T472_0202080	3.08e-07	53.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,25B01@186801|Clostridia,36JNT@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012,ko:K20534	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8,4.D.2.1.9	GT2	-	Glycos_transf_2
DTH2_k127_7107434_3	869213.JCM21142_93448	1.459e-38	145.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
DTH2_k127_7107434_2	1356852.N008_13190	9.291e-84	282.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,47P8Y@768503|Cytophagia	976|Bacteroidetes	S	PFAM Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
DTH2_k127_7107434_0	509635.N824_27860	6.31e-113	368.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_7107434_1	926549.KI421517_gene3832	4.732e-86	291.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,47N8Y@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
DTH2_k127_7125750_8	1408473.JHXO01000001_gene2257	4.747e-47	172.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DTH2_k127_7125750_3	509635.N824_05040	5.687e-253	799.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1IRKI@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DTH2_k127_7125750_7	504472.Slin_0515	1.239e-48	179.0	COG3428@1|root,COG3428@2|Bacteria,4NW40@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
DTH2_k127_7125750_9	468059.AUHA01000003_gene1651	7.039e-42	157.0	COG3874@1|root,COG3874@2|Bacteria,4NTIV@976|Bacteroidetes,1ITIB@117747|Sphingobacteriia	976|Bacteroidetes	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
DTH2_k127_7125750_5	1123248.KB893359_gene2012	1.199e-78	272.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1IQW1@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DTH2_k127_7125750_6	700598.Niako_2279	3.906e-58	209.0	COG0558@1|root,COG0558@2|Bacteria,4NHGH@976|Bacteroidetes,1IT19@117747|Sphingobacteriia	976|Bacteroidetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DTH2_k127_7125750_0	1492737.FEM08_32050	0.0	1482.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	fdsA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
DTH2_k127_7125750_1	1492737.FEM08_32040	4.07e-272	845.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1HYZ9@117743|Flavobacteriia,2NT0S@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
DTH2_k127_7125750_4	1492737.FEM08_32030	4.743e-95	319.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,1I19N@117743|Flavobacteriia,2NXF5@237|Flavobacterium	976|Bacteroidetes	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DTH2_k127_7125750_2	1313421.JHBV01000037_gene2910	5.681e-270	839.0	COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes	976|Bacteroidetes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
DTH2_k127_7131365_32	700598.Niako_5688	9.527e-31	123.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IR6P@117747|Sphingobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_7131365_20	445961.IW15_21245	1.717e-87	306.0	COG0521@1|root,COG0521@2|Bacteria,4NHV5@976|Bacteroidetes,1HXT5@117743|Flavobacteriia,3ZUQD@59732|Chryseobacterium	976|Bacteroidetes	H	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
DTH2_k127_7131365_4	1270193.JARP01000003_gene2021	8.364e-274	877.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,1HXFM@117743|Flavobacteriia,2P0KH@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_7131365_8	1239962.C943_04413	5.688e-172	544.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_7131365_3	929562.Emtol_2382	4.77e-299	927.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,47KM5@768503|Cytophagia	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
DTH2_k127_7131365_2	929562.Emtol_2383	5.044e-321	989.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,4NG9R@976|Bacteroidetes,47KDW@768503|Cytophagia	976|Bacteroidetes	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
DTH2_k127_7131365_34	927658.AJUM01000034_gene259	1.149e-22	102.0	2CICV@1|root,33IPP@2|Bacteria,4NXPC@976|Bacteroidetes,2FZJR@200643|Bacteroidia,3XKCG@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7131365_31	1123276.KB893247_gene222	1.437e-32	129.0	COG3411@1|root,COG3411@2|Bacteria,4NT2H@976|Bacteroidetes,47R8Z@768503|Cytophagia	976|Bacteroidetes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7131365_17	1270196.JCKI01000005_gene2923	4.19e-110	365.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH2_k127_7131365_11	509635.N824_13185	7.344e-155	493.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IPV3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_7131365_6	1434325.AZQN01000001_gene493	6.283e-235	751.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH2_k127_7131365_7	1121897.AUGO01000002_gene2405	2.64e-194	633.0	COG3203@1|root,COG3203@2|Bacteria,4PKUC@976|Bacteroidetes	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_7131365_14	926562.Oweho_2008	5.998e-136	441.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia,2PADC@246874|Cryomorphaceae	976|Bacteroidetes	S	Rhodanase C-terminal	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
DTH2_k127_7131365_13	1111730.ATTM01000007_gene2368	1.822e-139	449.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia,2NT4H@237|Flavobacterium	976|Bacteroidetes	GM	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_7131365_30	755732.Fluta_1974	4.462e-44	171.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_7131365_5	1123008.KB905696_gene2890	1.61e-250	779.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,22WDE@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DTH2_k127_7131365_16	926549.KI421517_gene497	1.479e-118	389.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH2_k127_7131365_22	755732.Fluta_1652	3.305e-78	264.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia,2PATB@246874|Cryomorphaceae	976|Bacteroidetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH2_k127_7131365_24	1336803.PHEL49_2500	2.108e-59	211.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia,3VVWS@52959|Polaribacter	976|Bacteroidetes	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
DTH2_k127_7131365_28	1121007.AUML01000039_gene3712	2.793e-45	177.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia,2YHD7@290174|Aquimarina	976|Bacteroidetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_7131365_19	509635.N824_27885	1.211e-99	331.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IQQ6@117747|Sphingobacteriia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DTH2_k127_7131365_27	1121957.ATVL01000009_gene1190	2.291e-45	175.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
DTH2_k127_7131365_25	1227739.Hsw_2480	4.78e-53	197.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
DTH2_k127_7131365_0	485917.Phep_4214	0.0	1141.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DTH2_k127_7131365_35	1408473.JHXO01000007_gene1001	0.0007604	49.0	COG3468@1|root,COG3468@2|Bacteria,4NEVR@976|Bacteroidetes	976|Bacteroidetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_7131365_18	485918.Cpin_6595	2.685e-101	350.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,1IVIF@117747|Sphingobacteriia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
DTH2_k127_7131365_23	1121481.AUAS01000001_gene4722	1.087e-71	250.0	COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia	976|Bacteroidetes	S	beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
DTH2_k127_7131365_9	1168034.FH5T_11290	7.211e-167	533.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DTH2_k127_7131365_26	1121904.ARBP01000010_gene2315	5.829e-52	190.0	COG2010@1|root,COG2010@2|Bacteria,4NSUK@976|Bacteroidetes,47R5S@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,SirB
DTH2_k127_7131365_1	929556.Solca_3432	0.0	1125.0	COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,1IQD3@117747|Sphingobacteriia	976|Bacteroidetes	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_7131365_15	1286632.P278_18060	9.144e-136	444.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_7131365_12	1237149.C900_03717	1.304e-147	473.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DTH2_k127_7131365_29	1408433.JHXV01000016_gene1862	4.907e-45	174.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia,2PB5B@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH2_k127_7131365_33	643867.Ftrac_3468	4.621e-29	118.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,47SA8@768503|Cytophagia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
DTH2_k127_7131365_10	929556.Solca_2810	2.349e-164	521.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
DTH2_k127_7131365_21	1150600.ADIARSV_4310	3.687e-81	280.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1IQUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
DTH2_k127_7160840_0	1150600.ADIARSV_2055	3.215e-291	914.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH2_k127_7160840_4	1123057.P872_10960	3.881e-65	227.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	gpx1	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
DTH2_k127_7160840_2	1185876.BN8_06112	6.125e-130	423.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_7160840_3	1356852.N008_05060	1.261e-88	304.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,47RR1@768503|Cytophagia	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
DTH2_k127_7160840_1	929556.Solca_0378	6.089e-159	509.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DTH2_k127_7160840_5	926562.Oweho_1584	9.851e-52	196.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH2_k127_7160840_6	929556.Solca_0380	1.31e-33	132.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DTH2_k127_7166868_3	714943.Mucpa_3930	2.324e-157	502.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_7166868_8	522306.CAP2UW1_4244	7.997e-36	139.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2VWVP@28216|Betaproteobacteria,1KR3H@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
DTH2_k127_7166868_0	509635.N824_09780	1.287e-261	810.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DTH2_k127_7166868_4	468059.AUHA01000003_gene1907	9.442e-142	458.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_7166868_2	755732.Fluta_0625	2.352e-209	657.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1HY08@117743|Flavobacteriia,2PBFC@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_7166868_7	468059.AUHA01000002_gene364	4.178e-62	220.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1IS5M@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
DTH2_k127_7166868_1	468059.AUHA01000002_gene365	1.475e-247	783.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,1IPAK@117747|Sphingobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
DTH2_k127_7166868_9	929556.Solca_4353	1.198e-22	99.0	COG1918@1|root,COG1918@2|Bacteria,4P9Q5@976|Bacteroidetes,1ITZ3@117747|Sphingobacteriia	976|Bacteroidetes	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
DTH2_k127_7166868_6	742725.HMPREF9450_00310	6.74e-90	304.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,2FNVR@200643|Bacteroidia,22U8J@171550|Rikenellaceae	976|Bacteroidetes	Q	Permease MlaE	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH2_k127_7166868_5	929556.Solca_2817	6.814e-105	349.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH2_k127_7166868_10	1408433.JHXV01000019_gene1976	0.0003061	43.0	COG3693@1|root,COG3693@2|Bacteria,4PPN9@976|Bacteroidetes,1I52M@117743|Flavobacteriia,2PBV1@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7169309_6	1089547.KB913013_gene61	7.545e-54	196.0	COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,47PZ0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_7169309_5	945713.IALB_3143	1.203e-57	205.0	COG0229@1|root,COG0229@2|Bacteria	2|Bacteria	O	peptide-methionine (R)-S-oxide reductase activity	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DTH2_k127_7169309_8	755732.Fluta_0888	7.502e-30	130.0	COG3291@1|root,COG3291@2|Bacteria,4PI05@976|Bacteroidetes,1ICSF@117743|Flavobacteriia,2PBZU@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_7169309_11	1297742.A176_07549	1.062e-09	68.0	2C2QD@1|root,33JG0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7169309_13	1121286.AUMT01000004_gene670	1.452e-07	63.0	COG5276@1|root,COG5276@2|Bacteria,4NJ21@976|Bacteroidetes,1IKP7@117743|Flavobacteriia,3ZSSI@59732|Chryseobacterium	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7169309_0	714943.Mucpa_3173	2.586e-247	773.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1INNX@117747|Sphingobacteriia	976|Bacteroidetes	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH2_k127_7169309_1	1408433.JHXV01000021_gene1703	5.089e-153	507.0	COG0526@1|root,COG0526@2|Bacteria,4NNXC@976|Bacteroidetes,1I2AF@117743|Flavobacteriia	976|Bacteroidetes	CO	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28,Thioredoxin
DTH2_k127_7169309_4	1150600.ADIARSV_2076	1.729e-82	277.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IRJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
DTH2_k127_7169309_10	755732.Fluta_2419	3.248e-15	81.0	2A94W@1|root,30Y96@2|Bacteria,4PC0G@976|Bacteroidetes,1ICSA@117743|Flavobacteriia,2PBZB@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7169309_9	1121898.Q766_15785	1.256e-20	108.0	COG1572@1|root,COG3291@1|root,COG3391@1|root,COG3405@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3405@2|Bacteria,4NWIZ@976|Bacteroidetes,1ICM5@117743|Flavobacteriia,2NVG1@237|Flavobacterium	976|Bacteroidetes	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH2_k127_7169309_12	1506583.JQJY01000002_gene1240	8.469e-08	66.0	COG1361@1|root,COG2373@1|root,COG3405@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG3405@2|Bacteria,4NMB8@976|Bacteroidetes,1IJ89@117743|Flavobacteriia,2P0KP@237|Flavobacterium	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Laminin_G_3,SdrD_B
DTH2_k127_7169309_3	391603.FBALC1_07508	3.569e-100	361.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NUCQ@976|Bacteroidetes	976|Bacteroidetes	C	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DTH2_k127_7169309_2	1122176.KB903546_gene1028	9.165e-145	481.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Cytochrome_C554,Glyco_hydro_26,PA14,RsgI_N
DTH2_k127_7169309_7	362418.IW19_00715	1.437e-41	159.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia,2NVDJ@237|Flavobacterium	976|Bacteroidetes	CO	cytochrome c biogenesis protein, transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH2_k127_7236488_14	1313421.JHBV01000004_gene763	4.419e-22	113.0	COG4935@1|root,COG4935@2|Bacteria,4NT9V@976|Bacteroidetes,1IYMI@117747|Sphingobacteriia	976|Bacteroidetes	O	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7236488_7	153721.MYP_3913	1.516e-60	239.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
DTH2_k127_7236488_2	762903.Pedsa_2763	4.15e-167	529.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia	976|Bacteroidetes	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_7236488_13	1121957.ATVL01000001_gene3499	1.508e-22	113.0	COG1409@1|root,COG2755@1|root,COG3209@1|root,COG1409@2|Bacteria,COG2755@2|Bacteria,COG3209@2|Bacteria,4P1IQ@976|Bacteroidetes,47UTQ@768503|Cytophagia	2|Bacteria	M	COG3209 Rhs family protein	yhcR	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	ChitinaseA_N
DTH2_k127_7236488_12	755732.Fluta_3357	6.502e-23	115.0	COG1357@1|root,COG1357@2|Bacteria,4PNZS@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_7236488_4	755732.Fluta_4031	3.14e-160	514.0	COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	lhgO	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
DTH2_k127_7236488_16	1454007.JAUG01000072_gene4108	2.051e-07	57.0	2BJXE@1|root,32E9W@2|Bacteria,4NRX8@976|Bacteroidetes,1ITBZ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
DTH2_k127_7236488_0	517418.Ctha_1714	0.0	1129.0	COG0612@1|root,COG0612@2|Bacteria,1FDGF@1090|Chlorobi	1090|Chlorobi	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_7236488_1	929703.KE386491_gene2166	1.941e-257	795.0	COG0538@1|root,COG0538@2|Bacteria,4NDY2@976|Bacteroidetes,47MTA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH2_k127_7236488_9	1202532.FF52_13371	2.283e-45	167.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia,2NWE0@237|Flavobacterium	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
DTH2_k127_7236488_5	1408433.JHXV01000006_gene2768	1.734e-82	284.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
DTH2_k127_7236488_3	1121896.JMLU01000028_gene2802	7.883e-165	531.0	COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia,2NSP1@237|Flavobacterium	976|Bacteroidetes	L	ATP-dependent endonuclease	recD2_2	-	3.1.11.5	ko:K01144	-	-	-	-	ko00000,ko01000	-	-	-	AAA_30,UvrD_C_2
DTH2_k127_7236488_10	983544.Lacal_2643	7.293e-43	169.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,1I24J@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
DTH2_k127_7236488_6	742725.HMPREF9450_01996	1.93e-61	216.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,2FSR0@200643|Bacteroidia,22UE7@171550|Rikenellaceae	976|Bacteroidetes	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
DTH2_k127_7236488_8	1408473.JHXO01000006_gene1207	1.898e-56	201.0	COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,2FT6A@200643|Bacteroidia	976|Bacteroidetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH2_k127_7236488_11	385682.AFSL01000024_gene2066	5.588e-33	145.0	COG0526@1|root,COG0526@2|Bacteria,4NNSW@976|Bacteroidetes,2FXHS@200643|Bacteroidia,3XJPK@558415|Marinilabiliaceae	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin_8
DTH2_k127_7236488_15	762903.Pedsa_0215	1.025e-12	69.0	COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1ITRK@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_7293969_6	313594.PI23P_03587	4.732e-59	213.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia,3VV80@52959|Polaribacter	976|Bacteroidetes	P	Di- and tricarboxylate transporters	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
DTH2_k127_7293969_0	755732.Fluta_1892	3.83e-240	767.0	COG1520@1|root,COG2312@1|root,COG4386@1|root,COG1520@2|Bacteria,COG2312@2|Bacteria,COG4386@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
DTH2_k127_7293969_8	1453500.AT05_06410	7.062e-08	66.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_7293969_5	755732.Fluta_1893	2.132e-60	221.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_7293969_1	926549.KI421517_gene1683	1.129e-135	437.0	COG1363@1|root,COG1363@2|Bacteria,4NH34@976|Bacteroidetes,47MR1@768503|Cytophagia	976|Bacteroidetes	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH2_k127_7293969_4	929556.Solca_1857	2.565e-73	252.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,1IQV2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0029, Impact, N-terminal	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
DTH2_k127_7293969_7	1121930.AQXG01000001_gene1275	4.456e-26	112.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,1IT0C@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
DTH2_k127_7293969_2	694427.Palpr_1368	5.029e-123	403.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,2FM4R@200643|Bacteroidia,22WQZ@171551|Porphyromonadaceae	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
DTH2_k127_7293969_3	391603.FBALC1_10182	1.062e-76	264.0	COG1611@1|root,COG2890@1|root,COG1611@2|Bacteria,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DTH2_k127_7303411_5	1123248.KB893318_gene4171	1.412e-93	310.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH2_k127_7303411_7	755732.Fluta_0111	1.025e-62	222.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia,2PAZY@246874|Cryomorphaceae	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH2_k127_7303411_3	485917.Phep_0983	5.761e-111	365.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DTH2_k127_7303411_8	755732.Fluta_1914	6.955e-59	214.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1IC3X@117743|Flavobacteriia,2PB1K@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_7303411_4	929556.Solca_0561	3.784e-106	350.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DTH2_k127_7303411_0	1453500.AT05_07935	1.32e-269	854.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
DTH2_k127_7303411_10	468059.AUHA01000006_gene2898	1.136e-53	194.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_7303411_11	485918.Cpin_1054	7.205e-27	116.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1ITN8@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_7303411_2	929556.Solca_2939	1.247e-119	392.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1IPZH@117747|Sphingobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
DTH2_k127_7303411_6	485918.Cpin_0426	3.931e-87	290.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1IS18@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_7303411_12	1166018.FAES_2981	7.001e-26	111.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,47S0M@768503|Cytophagia	976|Bacteroidetes	P	PFAM Heavy metal transport detoxification protein	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
DTH2_k127_7303411_1	1341181.FLJC2902T_07740	1.293e-199	645.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IIH0@117743|Flavobacteriia,2NUMU@237|Flavobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
DTH2_k127_7303411_13	1249997.JHZW01000002_gene1828	5.082e-17	83.0	COG3245@1|root,COG3245@2|Bacteria,4NRNS@976|Bacteroidetes,1I380@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7303411_9	1250232.JQNJ01000001_gene3935	4.401e-58	218.0	COG2960@1|root,COG2960@2|Bacteria,4NI9S@976|Bacteroidetes,1I0WS@117743|Flavobacteriia	976|Bacteroidetes	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7303411_14	700598.Niako_5150	6.401e-17	85.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH2_k127_7328011_1	1408433.JHXV01000043_gene3005	6.977e-118	386.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2PAGW@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH2_k127_7328011_0	1453498.LG45_06340	1.58e-199	638.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia,2NUAF@237|Flavobacterium	976|Bacteroidetes	U	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_7356543_4	1144313.PMI10_04235	1.075e-62	220.0	COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,1I16X@117743|Flavobacteriia,2NTTB@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF420)	yozB	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
DTH2_k127_7356543_2	1408433.JHXV01000001_gene696	1.116e-84	285.0	COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1I3NA@117743|Flavobacteriia,2PB1N@246874|Cryomorphaceae	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_7356543_0	1121007.AUML01000006_gene2998	4.218e-106	353.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1HZCI@117743|Flavobacteriia	976|Bacteroidetes	P	membrane protein TerC	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
DTH2_k127_7356543_1	1408433.JHXV01000001_gene697	1.891e-90	303.0	COG1999@1|root,COG1999@2|Bacteria,4PJEN@976|Bacteroidetes,1ICTB@117743|Flavobacteriia,2PC3D@246874|Cryomorphaceae	976|Bacteroidetes	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7356543_5	1408433.JHXV01000001_gene698	7.715e-43	160.0	COG5605@1|root,COG5605@2|Bacteria,4P9DD@976|Bacteroidetes,1IC4B@117743|Flavobacteriia,2PB81@246874|Cryomorphaceae	976|Bacteroidetes	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
DTH2_k127_7356543_3	1408433.JHXV01000001_gene699	2.379e-70	240.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia,2PAN3@246874|Cryomorphaceae	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_7359614_1	1408433.JHXV01000017_gene1629	2.2e-113	379.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,1I942@117743|Flavobacteriia,2PBH5@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
DTH2_k127_7359614_3	385682.AFSL01000003_gene1912	3.356e-56	198.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_7359614_2	755732.Fluta_2263	3.721e-58	207.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,1ICQH@117743|Flavobacteriia,2PBRJ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7359614_4	984262.SGRA_1773	3.921e-27	121.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,1IU2K@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7359614_0	1121904.ARBP01000006_gene4035	4.495e-249	806.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_7359614_5	755732.Fluta_4050	4.144e-24	102.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_7365532_6	755732.Fluta_0103	8.465e-16	91.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_2,CHU_C,PKD,SprB
DTH2_k127_7365532_7	491205.JARQ01000001_gene1163	1.509e-08	68.0	COG1470@1|root,COG3291@1|root,COG1470@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IIIM@117743|Flavobacteriia,3ZUIK@59732|Chryseobacterium	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,PKD,SprB
DTH2_k127_7365532_2	1107311.Q767_02430	7.69e-45	184.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4PPGH@976|Bacteroidetes,1IKM5@117743|Flavobacteriia,2NW1I@237|Flavobacterium	976|Bacteroidetes	O	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7365532_1	755732.Fluta_2725	1.646e-53	215.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
DTH2_k127_7365532_0	1453498.LG45_12305	4.943e-156	496.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia,2NT74@237|Flavobacterium	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH2_k127_7365532_5	525373.HMPREF0766_12817	7.885e-30	124.0	COG3577@1|root,COG3577@2|Bacteria,4PGFR@976|Bacteroidetes,1ITP7@117747|Sphingobacteriia	976|Bacteroidetes	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
DTH2_k127_7365532_3	1121007.AUML01000002_gene1569	1.206e-41	157.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia,2YJCW@290174|Aquimarina	976|Bacteroidetes	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
DTH2_k127_7365532_4	945713.IALB_1082	1.314e-32	143.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.1.3.1,3.1.3.5,3.1.3.8,3.6.1.45	ko:K01077,ko:K01083,ko:K07004,ko:K11751	ko00230,ko00240,ko00562,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00562,map00730,map00760,map00790,map01100,map01110,map02020	M00126	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R03371,R04620	RC00017,RC00078	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	5_nucleotid_C,Calx-beta,Phytase-like
DTH2_k127_7365532_8	1379698.RBG1_1C00001G0616	0.0003582	51.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_M6
DTH2_k127_7365532_9	926549.KI421517_gene1159	0.0009163	43.0	2EBMK@1|root,33NUV@2|Bacteria,4NXZ6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7365643_6	485917.Phep_3677	1.541e-33	130.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH2_k127_7365643_4	938709.AUSH02000046_gene105	4.822e-87	297.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes	976|Bacteroidetes	S	Alpha beta hydrolase	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH2_k127_7365643_3	755732.Fluta_2742	1.14e-134	455.0	COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,PLDc_2,Trypsin_2
DTH2_k127_7365643_0	755732.Fluta_2741	1.606e-205	672.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4PIMA@976|Bacteroidetes,1ICC3@117743|Flavobacteriia,2PBZQ@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug
DTH2_k127_7365643_5	755732.Fluta_2740	5.044e-41	163.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_7365643_1	1267211.KI669560_gene220	2.247e-195	610.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DTH2_k127_7365643_2	1229276.DI53_2833	5.462e-138	447.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
DTH2_k127_7365643_7	991.IW20_19220	3.38e-09	69.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4PHTJ@976|Bacteroidetes,1INB2@117743|Flavobacteriia,2NYWD@237|Flavobacterium	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7367793_15	762903.Pedsa_2084	5.109e-22	99.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1IPKQ@117747|Sphingobacteriia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DTH2_k127_7367793_7	313606.M23134_00008	1.225e-154	496.0	COG0334@1|root,COG0334@2|Bacteria,4NF3I@976|Bacteroidetes,47MHP@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH2_k127_7367793_2	929556.Solca_2344	1.799e-212	675.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1IPDM@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
DTH2_k127_7367793_14	927658.AJUM01000013_gene2634	5.588e-39	148.0	2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,2FS2B@200643|Bacteroidia,3XK7R@558415|Marinilabiliaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3276
DTH2_k127_7367793_16	1178825.ALIH01000015_gene1900	1.075e-18	87.0	2E77J@1|root,331RB@2|Bacteria,4NW0U@976|Bacteroidetes,1I5GK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7367793_13	203119.Cthe_2213	1.398e-57	206.0	COG4843@1|root,COG4843@2|Bacteria,1V5RI@1239|Firmicutes,25DG5@186801|Clostridia	186801|Clostridia	S	UPF0316 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
DTH2_k127_7367793_1	313606.M23134_02873	5.03e-214	696.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,47N4Z@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,MAM,TIG,fn3
DTH2_k127_7367793_10	153721.MYP_4023	7.969e-65	226.0	COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,47QHT@768503|Cytophagia	976|Bacteroidetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DTH2_k127_7367793_11	1237149.C900_04937	4.76e-64	231.0	COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,47MFN@768503|Cytophagia	976|Bacteroidetes	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Phytase-like
DTH2_k127_7367793_4	118163.Ple7327_2936	1.198e-182	584.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,3VIVK@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
DTH2_k127_7367793_5	1173264.KI913949_gene2380	2.32e-182	581.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1H8G7@1150|Oscillatoriales	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
DTH2_k127_7367793_18	1462527.CCDM010000002_gene805	2.357e-05	53.0	COG2318@1|root,COG2318@2|Bacteria,1V6FD@1239|Firmicutes,4HJI8@91061|Bacilli	91061|Bacilli	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
DTH2_k127_7367793_6	929556.Solca_1863	4.304e-173	550.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DTH2_k127_7367793_9	929556.Solca_2806	2.309e-86	291.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_7367793_12	153721.MYP_530	3.722e-59	210.0	COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes,47XM3@768503|Cytophagia	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
DTH2_k127_7367793_3	1046627.BZARG_1122	3.524e-200	657.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
DTH2_k127_7367793_0	926549.KI421517_gene2964	6.026e-218	695.0	COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
DTH2_k127_7367793_8	929562.Emtol_0702	1.508e-150	504.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
DTH2_k127_73717_0	929558.SMGD1_0478	2.265e-45	173.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2YMSE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
DTH2_k127_73717_2	1268237.G114_10590	4.209e-10	69.0	COG1670@1|root,COG1670@2|Bacteria,1RKAB@1224|Proteobacteria,1S5YC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_73717_1	402777.KB235906_gene310	1.473e-23	113.0	COG0615@1|root,COG1216@1|root,COG0615@2|Bacteria,COG1216@2|Bacteria,1G1YM@1117|Cyanobacteria,1HHMP@1150|Oscillatoriales	1117|Cyanobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_7374471_3	1453498.LG45_13550	4.299e-46	173.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,1I1E1@117743|Flavobacteriia,2NVWR@237|Flavobacterium	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
DTH2_k127_7374471_2	746697.Aeqsu_0111	6.028e-47	176.0	COG1999@1|root,COG1999@2|Bacteria,4NN4N@976|Bacteroidetes,1I17P@117743|Flavobacteriia	976|Bacteroidetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_7374471_1	925409.KI911562_gene2470	1.756e-83	284.0	COG1262@1|root,COG1262@2|Bacteria,4NGBN@976|Bacteroidetes,1IUAX@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_7374471_0	1051985.l11_03490	4.865e-203	642.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2VK95@28216|Betaproteobacteria,2KQR4@206351|Neisseriales	206351|Neisseriales	C	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3
DTH2_k127_7374471_4	1121887.AUDK01000005_gene3029	3.179e-29	121.0	COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1I00C@117743|Flavobacteriia,2NUFJ@237|Flavobacterium	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7453705_17	714943.Mucpa_1106	1.059e-115	377.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_7453705_33	272123.Anacy_4774	0.0004035	45.0	COG0614@1|root,COG0614@2|Bacteria,1G71C@1117|Cyanobacteria,1HP4K@1161|Nostocales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_7453705_30	313624.NSP_44690	2.122e-28	116.0	COG0614@1|root,COG0614@2|Bacteria,1G71C@1117|Cyanobacteria,1HP4K@1161|Nostocales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_7453705_5	1408433.JHXV01000011_gene2002	1.388e-193	612.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia,2PAF8@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
DTH2_k127_7453705_3	1408433.JHXV01000011_gene2000	3.179e-204	643.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,1HXAE@117743|Flavobacteriia,2PA4J@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
DTH2_k127_7453705_13	468059.AUHA01000002_gene413	1.169e-138	462.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1INS7@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
DTH2_k127_7453705_29	926562.Oweho_1648	3.826e-31	124.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia,2PB6J@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
DTH2_k127_7453705_21	762903.Pedsa_3302	3.699e-98	327.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1IR07@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DTH2_k127_7453705_16	1128421.JAGA01000002_gene854	8.075e-117	391.0	COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria	2|Bacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N,PRC
DTH2_k127_7453705_20	1121895.Q765_19960	1.87e-110	365.0	COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,1HXGX@117743|Flavobacteriia,2NSA1@237|Flavobacterium	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH2_k127_7453705_22	755732.Fluta_1284	4.295e-88	311.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_7453705_9	929556.Solca_2028	1.443e-171	548.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_7453705_26	1279009.ADICEAN_03093	9.484e-58	206.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
DTH2_k127_7453705_8	929556.Solca_1338	1.544e-172	546.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
DTH2_k127_7453705_0	1041826.FCOL_08320	0.0	1335.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia,2NSWW@237|Flavobacterium	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
DTH2_k127_7453705_31	755732.Fluta_0090	8.166e-14	80.0	COG4743@1|root,COG4743@2|Bacteria,4NU7A@976|Bacteroidetes,1I314@117743|Flavobacteriia,2PB9G@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7453705_18	1124780.ANNU01000017_gene1898	1.312e-115	383.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_7453705_12	1270196.JCKI01000004_gene1003	2.354e-143	465.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1IR94@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_7453705_1	929556.Solca_0356	2.217e-234	734.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1IP42@117747|Sphingobacteriia	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DTH2_k127_7453705_6	755732.Fluta_1895	6.102e-187	587.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia,2PACA@246874|Cryomorphaceae	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DTH2_k127_7453705_25	1168289.AJKI01000011_gene652	2.368e-61	221.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia,3XIT1@558415|Marinilabiliaceae	976|Bacteroidetes	M	rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DTH2_k127_7453705_27	1408473.JHXO01000011_gene2964	4.742e-45	168.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,2FPJA@200643|Bacteroidia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7453705_4	1408473.JHXO01000011_gene2965	2.2e-195	627.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,2FM4X@200643|Bacteroidia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
DTH2_k127_7453705_14	926562.Oweho_0087	2.72e-131	431.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1HXI4@117743|Flavobacteriia,2PAKS@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell cycle protein	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
DTH2_k127_7453705_11	1121904.ARBP01000007_gene2943	3.23e-149	488.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7453705_7	926549.KI421517_gene738	5.026e-184	582.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,47N2Y@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DTH2_k127_7453705_2	926549.KI421517_gene739	1.718e-225	707.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,47JAE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DTH2_k127_7453705_23	269798.CHU_3743	9.227e-84	283.0	COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,47NNG@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
DTH2_k127_7453705_10	926549.KI421517_gene744	6.454e-157	502.0	COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,47MDN@768503|Cytophagia	976|Bacteroidetes	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH2_k127_7453705_19	385682.AFSL01000082_gene1182	9.626e-114	394.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,3XJMY@558415|Marinilabiliaceae	976|Bacteroidetes	O	SurA N-terminal domain	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
DTH2_k127_7453705_15	926562.Oweho_0085	7.368e-126	415.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia,2PA4U@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
DTH2_k127_7453705_28	929556.Solca_4295	1.123e-35	143.0	COG3117@1|root,COG3117@2|Bacteria,4NV8G@976|Bacteroidetes,1IU6N@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
DTH2_k127_7453705_24	468059.AUHA01000002_gene1132	1.24e-66	246.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7454675_3	714943.Mucpa_5277	1.028e-08	58.0	COG5580@1|root,COG5580@2|Bacteria,4NQ7U@976|Bacteroidetes,1ISR1@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DTH2_k127_7454675_1	926562.Oweho_0994	8.75e-58	218.0	2ENVG@1|root,33GGJ@2|Bacteria,4P2K9@976|Bacteroidetes,1I8MZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7454675_0	929556.Solca_1912	6.128e-95	317.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1IRFD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_7454675_2	926562.Oweho_1029	3.667e-24	103.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,1I8FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7494586_2	926549.KI421517_gene119	5.421e-176	567.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_7494586_0	714943.Mucpa_4396	8.009e-227	719.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1IPN2@117747|Sphingobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH2_k127_7494586_3	927658.AJUM01000037_gene2123	2.623e-82	282.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia,3XJ7Z@558415|Marinilabiliaceae	976|Bacteroidetes	S	Eukaryotic integral membrane protein (DUF1751)	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
DTH2_k127_7494586_5	1124780.ANNU01000017_gene1943	2.074e-60	219.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,47JAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_7494586_4	1408433.JHXV01000010_gene542	2.522e-81	286.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia,2PAXM@246874|Cryomorphaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_7494586_1	926562.Oweho_0107	1.657e-181	583.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1HWV6@117743|Flavobacteriia,2PBBY@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_7508295_2	1123277.KB893184_gene3960	8.838e-40	149.0	COG0713@1|root,COG0713@2|Bacteria,4NPKF@976|Bacteroidetes,47XUW@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH2_k127_7508295_0	468059.AUHA01000002_gene1094	2.104e-262	822.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
DTH2_k127_7508295_1	714943.Mucpa_3118	1.684e-185	591.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
DTH2_k127_7508295_3	485917.Phep_4069	1.716e-08	58.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH2_k127_758736_0	391587.KAOT1_05072	3.861e-167	537.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,1HWWM@117743|Flavobacteriia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
DTH2_k127_758736_1	1121896.JMLU01000016_gene1685	3.656e-158	502.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia,2NSQA@237|Flavobacterium	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
DTH2_k127_758736_3	1453505.JASY01000007_gene1198	0.0004358	51.0	COG3637@1|root,COG3637@2|Bacteria,4PCBQ@976|Bacteroidetes,1ICYE@117743|Flavobacteriia,2NW4Z@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_758736_2	391596.PBAL39_08085	1.326e-18	85.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1IPN9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_7740851_3	153721.MYP_20	3.984e-54	196.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,47JIS@768503|Cytophagia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7740851_4	485918.Cpin_0942	1.401e-48	176.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1IT12@117747|Sphingobacteriia	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_7740851_5	742817.HMPREF9449_00183	1.169e-14	80.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,2FYEI@200643|Bacteroidia,230HI@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7740851_8	742817.HMPREF9449_00183	5.184e-09	63.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,2FYEI@200643|Bacteroidia,230HI@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7740851_7	709991.Odosp_1618	3.411e-12	72.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,2FYEI@200643|Bacteroidia,230HI@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7740851_1	755732.Fluta_2750	2.539e-174	563.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia,2PBBJ@246874|Cryomorphaceae	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
DTH2_k127_7740851_0	1454007.JAUG01000024_gene828	5.223e-239	748.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DTH2_k127_7740851_2	929562.Emtol_1901	3.599e-136	444.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,47NAK@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM ribosomal RNA small subunit methyltransferase RsmB	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
DTH2_k127_776734_5	179408.Osc7112_2624	3.736e-32	126.0	COG1619@1|root,COG1619@2|Bacteria,1G059@1117|Cyanobacteria,1H7XC@1150|Oscillatoriales	1117|Cyanobacteria	V	microcin C7 resistance	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
DTH2_k127_776734_3	313606.M23134_03474	1.813e-91	328.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,47TYP@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
DTH2_k127_776734_1	1313421.JHBV01000030_gene2110	1.836e-113	407.0	COG2132@1|root,COG3209@1|root,COG2132@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	CHU_C,Copper-bind,Cu-oxidase_3,SprB
DTH2_k127_776734_4	1270196.JCKI01000001_gene3855	3.897e-37	163.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_776734_6	1034807.FBFL15_2377	7.822e-16	86.0	2AD0U@1|root,312NT@2|Bacteria,4PHMV@976|Bacteroidetes,1IDQF@117743|Flavobacteriia,2NYYD@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_776734_0	926562.Oweho_1923	4.749e-306	946.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia,2PAMC@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Cytochrome C and Quinol oxidase polypeptide I	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DTH2_k127_776734_2	867900.Celly_1862	1.735e-101	342.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia,1F8GP@104264|Cellulophaga	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, transmembrane domain	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
DTH2_k127_7822204_2	1121286.AUMT01000011_gene2402	6.744e-114	377.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1HWX7@117743|Flavobacteriia,3ZQ3H@59732|Chryseobacterium	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
DTH2_k127_7822204_0	1237149.C900_04460	3.205e-210	657.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47JZA@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_7822204_1	468059.AUHA01000003_gene1714	7.898e-155	503.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia	976|Bacteroidetes	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
DTH2_k127_7829920_2	926549.KI421517_gene2227	1.843e-122	407.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_7829920_3	867902.Ornrh_0947	3.117e-56	199.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1I24B@117743|Flavobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
DTH2_k127_7829920_1	485918.Cpin_0742	3.452e-161	512.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
DTH2_k127_7829920_0	926549.KI421517_gene1040	3.145e-295	917.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
DTH2_k127_7858639_2	153721.MYP_3099	3.04e-200	674.0	COG2152@1|root,COG3291@1|root,COG2152@2|Bacteria,COG3291@2|Bacteria,4PHTS@976|Bacteroidetes,47Q40@768503|Cytophagia	976|Bacteroidetes	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_7858639_17	1239962.C943_02008	1.444e-24	122.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia	976|Bacteroidetes	O	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_7858639_9	485918.Cpin_2197	1.983e-51	194.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_7858639_0	485918.Cpin_1945	1.706e-255	802.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DTH2_k127_7858639_1	929556.Solca_3521	1.564e-219	694.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
DTH2_k127_7858639_22	714943.Mucpa_2551	1.835e-06	49.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7858639_15	468059.AUHA01000002_gene681	4.846e-29	127.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
DTH2_k127_7858639_13	926562.Oweho_3000	1.399e-39	149.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia,2PAZN@246874|Cryomorphaceae	976|Bacteroidetes	L	bacterial (prokaryotic) histone like domain	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_7858639_5	929556.Solca_3518	2.303e-120	396.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1IPZD@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DTH2_k127_7858639_10	1150600.ADIARSV_2092	2.627e-49	180.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ISJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH2_k127_7858639_4	926562.Oweho_3003	2.468e-125	415.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DTH2_k127_7858639_8	485917.Phep_4156	5.25e-55	200.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7858639_6	1250232.JQNJ01000001_gene230	3.934e-109	363.0	COG1612@1|root,COG1612@2|Bacteria,4NIT1@976|Bacteroidetes,1HXU5@117743|Flavobacteriia	976|Bacteroidetes	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
DTH2_k127_7858639_16	1408433.JHXV01000020_gene3544	1.116e-24	113.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_7858639_14	1408813.AYMG01000001_gene3694	2.049e-39	154.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_7858639_19	755732.Fluta_2493	2.516e-13	81.0	COG1729@1|root,COG1729@2|Bacteria,4PIUE@976|Bacteroidetes,1ICSH@117743|Flavobacteriia,2PC00@246874|Cryomorphaceae	976|Bacteroidetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7858639_20	269798.CHU_2011	1.815e-11	70.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
DTH2_k127_7858639_7	1237149.C900_02777	1.01e-73	258.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_7858639_11	1506583.JQJY01000002_gene1351	7.896e-43	161.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia,2NW0E@237|Flavobacterium	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
DTH2_k127_7858639_12	929556.Solca_1233	2.195e-41	153.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1IT8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DTH2_k127_7858639_3	1150600.ADIARSV_4176	3.783e-146	469.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DTH2_k127_7931414_0	1313421.JHBV01000041_gene3662	2.227e-128	417.0	COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1IPUJ@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
DTH2_k127_7931414_2	926562.Oweho_3447	4.198e-85	293.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia	2|Bacteria	C	cytochrome C peroxidase	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
DTH2_k127_7931414_4	926562.Oweho_3448	8.759e-32	133.0	28JFU@1|root,30YB4@2|Bacteria,4PC31@976|Bacteroidetes,1ICTS@117743|Flavobacteriia,2PC4T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7931414_1	1121012.AUKX01000020_gene1873	3.913e-100	343.0	COG3203@1|root,COG3203@2|Bacteria,4NDYW@976|Bacteroidetes,1HWYP@117743|Flavobacteriia,23GSE@178469|Arenibacter	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
DTH2_k127_7931414_5	1041826.FCOL_02080	6.358e-20	90.0	COG2223@1|root,COG2223@2|Bacteria,4NJ57@976|Bacteroidetes,1HWYX@117743|Flavobacteriia,2NV1N@237|Flavobacterium	976|Bacteroidetes	P	Transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,MgtE_N
DTH2_k127_7964403_3	468059.AUHA01000002_gene32	2.733e-116	389.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DTH2_k127_7964403_5	926562.Oweho_1586	3.246e-92	309.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia,2PAR7@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH2_k127_7964403_1	1168289.AJKI01000031_gene966	5.326e-178	567.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,2FMTV@200643|Bacteroidia,3XJHM@558415|Marinilabiliaceae	976|Bacteroidetes	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_7964403_2	468059.AUHA01000003_gene1886	6.744e-168	535.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_7964403_4	1408433.JHXV01000001_gene683	1.435e-103	339.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia,2PA5G@246874|Cryomorphaceae	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
DTH2_k127_7964403_7	1123248.KB893319_gene4068	1.487e-26	119.0	2CGN1@1|root,3348T@2|Bacteria,4NX4E@976|Bacteroidetes,1IUF2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7964403_0	509635.N824_28660	9.507e-215	677.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,1J0QZ@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_7964403_6	761193.Runsl_0050	2.06e-31	124.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,47KZJ@768503|Cytophagia	976|Bacteroidetes	L	PFAM PHP domain	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,HHH_8,PHP
DTH2_k127_7968288_6	1121904.ARBP01000005_gene4875	1.214e-07	55.0	2FE32@1|root,34635@2|Bacteria,4P58J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CutA1
DTH2_k127_7968288_0	402612.FP1027	0.0	1071.0	COG0826@1|root,COG0826@2|Bacteria,4NEX7@976|Bacteroidetes,1I8IA@117743|Flavobacteriia,2NV2M@237|Flavobacterium	976|Bacteroidetes	O	Peptidase U32	prtQ	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
DTH2_k127_7968288_3	1189620.AJXL01000130_gene1664	2.364e-73	256.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia,2NV4H@237|Flavobacterium	976|Bacteroidetes	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_7968288_2	1094466.KQS_05795	2.972e-87	308.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2NSD2@237|Flavobacterium	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7968288_1	1094466.KQS_05805	1.26e-135	469.0	COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,DUF4347
DTH2_k127_7968288_4	1313421.JHBV01000005_gene4512	1.57e-18	102.0	COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_7968288_5	984262.SGRA_2241	1.62e-13	75.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IQ3Y@117747|Sphingobacteriia	976|Bacteroidetes	I	protein CHP03519, membrane, Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8009730_2	153721.MYP_198	6.076e-56	214.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8009730_3	926556.Echvi_2072	1.901e-12	76.0	2AEI8@1|root,331SH@2|Bacteria,4NWWM@976|Bacteroidetes,47S6K@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8009730_1	929556.Solca_1416	1.753e-91	305.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
DTH2_k127_8009730_0	714943.Mucpa_4254	6.56e-279	870.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
DTH2_k127_8046095_4	929556.Solca_2743	2.443e-190	616.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH2_k127_8046095_2	1408813.AYMG01000017_gene5505	1.216e-206	652.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_8046095_5	926562.Oweho_2827	8.878e-188	594.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia,2PAGT@246874|Cryomorphaceae	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
DTH2_k127_8046095_3	762903.Pedsa_0132	1.106e-193	612.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH2_k127_8046095_18	518766.Rmar_2703	1.818e-31	129.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1FITH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH2_k127_8046095_11	700598.Niako_7322	5.477e-101	341.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DTH2_k127_8046095_10	1122226.AUHX01000004_gene1876	3.431e-135	440.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DTH2_k127_8046095_9	929556.Solca_2737	1.776e-156	507.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_8046095_14	1408813.AYMG01000017_gene5511	4.474e-51	190.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IRV2@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
DTH2_k127_8046095_6	1408433.JHXV01000032_gene1130	4.711e-184	584.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia,2PA5T@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DTH2_k127_8046095_7	1408433.JHXV01000032_gene1131	3.596e-165	537.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DTH2_k127_8046095_13	1341181.FLJC2902T_09550	5.254e-53	192.0	COG4803@1|root,COG4803@2|Bacteria,4PCAJ@976|Bacteroidetes,1I913@117743|Flavobacteriia,2NVVC@237|Flavobacterium	976|Bacteroidetes	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8046095_15	1538644.KO02_07795	1.829e-43	164.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1IT3W@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
DTH2_k127_8046095_12	504472.Slin_5735	6.93e-64	228.0	28IS5@1|root,2Z8RB@2|Bacteria,4NIIH@976|Bacteroidetes,47R7X@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8046095_0	929556.Solca_4126	9.86e-275	852.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH2_k127_8046095_17	926549.KI421517_gene3100	1.236e-36	140.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DTH2_k127_8046095_20	709991.Odosp_2375	7.556e-23	102.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia,22YIT@171551|Porphyromonadaceae	976|Bacteroidetes	U	Preprotein translocase	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
DTH2_k127_8046095_19	755732.Fluta_2281	1.532e-29	131.0	2ABIA@1|root,310ZH@2|Bacteria,4PFMS@976|Bacteroidetes,1ICAQ@117743|Flavobacteriia,2PB8S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8046095_16	1168034.FH5T_05450	1.754e-40	155.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,2FSVU@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG14471 non supervised orthologous group	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
DTH2_k127_8046095_8	1150600.ADIARSV_1521	3.331e-163	522.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
DTH2_k127_8046095_1	485917.Phep_0249	3.583e-209	659.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1IPSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_8054634_2	1408473.JHXO01000013_gene619	7.482e-159	511.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,2FNW2@200643|Bacteroidia	976|Bacteroidetes	Q	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_8054634_0	709991.Odosp_0734	3.518e-259	808.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,22WZC@171551|Porphyromonadaceae	976|Bacteroidetes	E	Glutamate formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
DTH2_k127_8054634_1	153721.MYP_4656	2.698e-164	543.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
DTH2_k127_8054634_3	755732.Fluta_2685	6.545e-07	55.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_80556_0	1313421.JHBV01000029_gene1873	8.746e-165	572.0	COG3291@1|root,COG3291@2|Bacteria,4PHX4@976|Bacteroidetes,1IXHW@117747|Sphingobacteriia	976|Bacteroidetes	N	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_80556_8	1408433.JHXV01000015_gene1755	1.037e-19	106.0	COG4386@1|root,COG5384@1|root,COG4386@2|Bacteria,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes,1IKB1@117743|Flavobacteriia	976|Bacteroidetes	J	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,TSP_3
DTH2_k127_80556_2	1408433.JHXV01000004_gene3380	1.231e-87	299.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia,2PBE9@246874|Cryomorphaceae	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_80556_1	926562.Oweho_1836	7.34e-129	421.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia,2PAFN@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_80556_3	1048983.EL17_17680	2.738e-77	267.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,47NUX@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_80556_5	755732.Fluta_2219	6.556e-47	176.0	COG2197@1|root,COG2197@2|Bacteria,4NN0B@976|Bacteroidetes,1I0A6@117743|Flavobacteriia	976|Bacteroidetes	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_80556_4	755732.Fluta_2220	1.806e-71	266.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI9U@976|Bacteroidetes,1HX1I@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_7
DTH2_k127_80556_6	755732.Fluta_2725	5.733e-43	183.0	COG3210@1|root,COG3291@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IKDY@117743|Flavobacteriia,2PC6N@246874|Cryomorphaceae	976|Bacteroidetes	U	SPTR Conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SASA,SprB
DTH2_k127_811087_9	1408473.JHXO01000004_gene133	0.0005303	44.0	2EQMK@1|root,33I7I@2|Bacteria,4NY3R@976|Bacteroidetes,2FVUP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_811087_3	1408433.JHXV01000009_gene1283	7.235e-116	379.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1HWWP@117743|Flavobacteriia,2PA7K@246874|Cryomorphaceae	976|Bacteroidetes	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
DTH2_k127_811087_1	926562.Oweho_0913	5.664e-147	472.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia,2PAD7@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH2_k127_811087_6	643473.KB235930_gene3528	4.235e-34	145.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1HKUX@1161|Nostocales	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
DTH2_k127_811087_2	880073.Calab_2100	4.999e-140	465.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
DTH2_k127_811087_5	313606.M23134_06902	1.19e-47	193.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,Peptidase_M43
DTH2_k127_811087_7	869213.JCM21142_93400	3.315e-13	83.0	COG3291@1|root,COG3291@2|Bacteria,4PHYT@976|Bacteroidetes,47WXR@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_811087_8	32057.KB217478_gene5219	0.0004119	48.0	COG1262@1|root,COG1262@2|Bacteria,1GQ3K@1117|Cyanobacteria	2|Bacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,TIR_2
DTH2_k127_811087_4	929703.KE386491_gene2724	1.248e-81	276.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DTH2_k127_811087_0	926549.KI421517_gene3433	1.471e-151	485.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47N3X@768503|Cytophagia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
DTH2_k127_8138864_0	1122621.ATZA01000012_gene3157	1.661e-229	728.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,1IPQP@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
DTH2_k127_8138864_1	700598.Niako_6250	3.147e-45	167.0	COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_8138864_2	485918.Cpin_1880	1.122e-44	168.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH2_k127_8207644_0	929556.Solca_2664	0.0	1299.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_8207644_37	1313421.JHBV01000019_gene5364	1.104e-33	154.0	COG3291@1|root,COG3291@2|Bacteria,4NICC@976|Bacteroidetes,1IXKI@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8207644_13	391596.PBAL39_09831	1.02e-136	442.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,1IPQV@117747|Sphingobacteriia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
DTH2_k127_8207644_31	1408433.JHXV01000006_gene2725	1.22e-72	254.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia,2PAQC@246874|Cryomorphaceae	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
DTH2_k127_8207644_1	926549.KI421517_gene3703	0.0	1280.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,47MI0@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
DTH2_k127_8207644_39	755732.Fluta_2355	2.869e-24	108.0	2ED7H@1|root,33743@2|Bacteria,4NYV3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8207644_24	1122226.AUHX01000007_gene2621	1.56e-89	303.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1HXFX@117743|Flavobacteriia	976|Bacteroidetes	D	Required for cell division and gliding motility	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
DTH2_k127_8207644_40	485918.Cpin_1256	3.926e-23	101.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,1IUJM@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3098)	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
DTH2_k127_8207644_23	1120968.AUBX01000015_gene3511	5.087e-91	306.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DTH2_k127_8207644_22	1250005.PHEL85_1831	6.967e-94	314.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia,3VV5P@52959|Polaribacter	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
DTH2_k127_8207644_9	755732.Fluta_0923	1.084e-183	579.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia,2PA7J@246874|Cryomorphaceae	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DTH2_k127_8207644_34	153721.MYP_87	8.96e-65	228.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,47P6K@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
DTH2_k127_8207644_20	468059.AUHA01000002_gene1183	7.555e-100	338.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes,1IPAQ@117747|Sphingobacteriia	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DTH2_k127_8207644_11	929556.Solca_4335	8.747e-160	510.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1IQMY@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_8207644_14	525373.HMPREF0766_10345	1.233e-136	441.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH2_k127_8207644_47	1121373.KB903643_gene3461	3.393e-10	66.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_8207644_44	319236.JCM19294_1035	6.907e-13	79.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,3HJTQ@363408|Nonlabens	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DTH2_k127_8207644_46	1349785.BAUG01000033_gene1884	1.607e-10	66.0	COG2010@1|root,COG2010@2|Bacteria,4PBRD@976|Bacteroidetes,1I5EJ@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8207644_35	1408813.AYMG01000014_gene1593	7.608e-47	174.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,1IY6E@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Lipid polyisoprenoid-binding, YceI-like	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_8207644_29	269798.CHU_0350	2.423e-76	266.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8207644_43	485917.Phep_0381	3.103e-18	94.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,1IUMD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
DTH2_k127_8207644_17	385682.AFSL01000096_gene594	5.307e-108	355.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,2FMX9@200643|Bacteroidia,3XIXK@558415|Marinilabiliaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
DTH2_k127_8207644_41	1121097.JCM15093_1068	1.808e-21	98.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,2FSYK@200643|Bacteroidia,4AVJS@815|Bacteroidaceae	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DTH2_k127_8207644_38	509635.N824_03010	3.267e-31	124.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DTH2_k127_8207644_7	929556.Solca_2578	1.197e-198	634.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_8207644_33	1168034.FH5T_14375	2.409e-72	264.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K16705	-	-	-	-	ko00000	-	-	-	Wzy_C
DTH2_k127_8207644_16	929703.KE386491_gene143	8.88e-121	396.0	COG1216@1|root,COG1216@2|Bacteria,4NGF3@976|Bacteroidetes,47PKW@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8207644_30	1387197.AWGA01000063_gene308	5.611e-73	253.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8207644_18	929556.Solca_3477	2.412e-107	355.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1IQ92@117747|Sphingobacteriia	976|Bacteroidetes	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DTH2_k127_8207644_3	485918.Cpin_0233	1.411e-290	913.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
DTH2_k127_8207644_27	679935.Alfi_1286	1.657e-82	278.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
DTH2_k127_8207644_48	886379.AEWI01000031_gene276	1.337e-08	64.0	2EKSY@1|root,33EGP@2|Bacteria,4NXJC@976|Bacteroidetes,2FVKV@200643|Bacteroidia,3XK4T@558415|Marinilabiliaceae	976|Bacteroidetes	S	COG NOG23390 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8207644_21	313606.M23134_04150	2.389e-95	328.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,47NIK@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_8207644_19	1121481.AUAS01000007_gene962	3.516e-101	334.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH2_k127_8207644_15	1047013.AQSP01000110_gene67	8.894e-123	402.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DTH2_k127_8207644_4	755732.Fluta_0844	9.916e-233	739.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH2_k127_8207644_6	929556.Solca_4406	3.561e-218	690.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1IQ3R@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_8207644_8	525373.HMPREF0766_10662	1.679e-195	629.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
DTH2_k127_8207644_45	1229487.AMYW01000008_gene1065	2.845e-11	76.0	COG1680@1|root,COG2976@1|root,COG1680@2|Bacteria,COG2976@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
DTH2_k127_8207644_28	1121904.ARBP01000006_gene3769	2.39e-82	292.0	COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes	976|Bacteroidetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
DTH2_k127_8207644_5	1341181.FLJC2902T_01740	2.043e-218	683.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia,2NSBD@237|Flavobacterium	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_8207644_25	938709.AUSH02000031_gene1321	2.125e-88	299.0	COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_8207644_10	1237149.C900_02885	8.35e-180	573.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
DTH2_k127_8207644_42	589924.Ferp_1321	1.9e-19	93.0	COG0607@1|root,arCOG02021@2157|Archaea,2XY1R@28890|Euryarchaeota,246BX@183980|Archaeoglobi	183980|Archaeoglobi	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_8207644_12	1408813.AYMG01000011_gene721	3.513e-139	445.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
DTH2_k127_8207644_2	509635.N824_09470	0.0	1130.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1IQ4F@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_8207644_32	1454007.JAUG01000065_gene4692	1.598e-72	251.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,1ISIA@117747|Sphingobacteriia	976|Bacteroidetes	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
DTH2_k127_8207644_26	1408433.JHXV01000026_gene3014	1.053e-83	307.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,4NRDH@976|Bacteroidetes,1IIK5@117743|Flavobacteriia,2PBFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8207644_36	1121899.Q764_13760	5.249e-36	158.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4NDZQ@976|Bacteroidetes,1IKR6@117743|Flavobacteriia,2P0US@237|Flavobacterium	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SprB
DTH2_k127_8218170_0	755732.Fluta_1682	0.0	1129.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_8218170_1	1408433.JHXV01000027_gene3728	2.417e-212	697.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_8218170_2	1121373.KB903665_gene3064	2.821e-92	309.0	COG2102@1|root,COG2102@2|Bacteria,4NFQ4@976|Bacteroidetes,47Q0E@768503|Cytophagia	976|Bacteroidetes	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
DTH2_k127_8218170_3	929703.KE386491_gene1232	1.913e-62	240.0	COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,47PMZ@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
DTH2_k127_8218170_4	545697.HMPREF0216_00702	5.455e-61	214.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,36EC2@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_8218170_5	755732.Fluta_0327	7.516e-44	171.0	2D45Q@1|root,32TGB@2|Bacteria,4NTFZ@976|Bacteroidetes,1IBQ1@117743|Flavobacteriia,2PBMI@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8236835_12	1121373.KB903627_gene2912	1.878e-88	292.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DTH2_k127_8236835_18	1237149.C900_02640	1.289e-54	196.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,47Q9G@768503|Cytophagia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
DTH2_k127_8236835_27	1250232.JQNJ01000001_gene3222	1.287e-25	117.0	2DNQ3@1|root,32YIN@2|Bacteria,4NUWB@976|Bacteroidetes,1I6EI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8236835_10	925409.KI911562_gene2570	4.166e-99	327.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DTH2_k127_8236835_4	929556.Solca_1149	1.216e-187	593.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DTH2_k127_8236835_9	755732.Fluta_2300	2.588e-116	377.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia,2PA6J@246874|Cryomorphaceae	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DTH2_k127_8236835_7	1408433.JHXV01000011_gene2093	1.445e-123	410.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
DTH2_k127_8236835_28	927658.AJUM01000034_gene122	4.654e-23	99.0	COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,2G1ET@200643|Bacteroidia,3XKE0@558415|Marinilabiliaceae	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DTH2_k127_8236835_5	755732.Fluta_1284	3.284e-129	441.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_8236835_22	755732.Fluta_1284	2.684e-38	160.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_8236835_8	1408433.JHXV01000015_gene1787	2.566e-117	384.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia,2PA79@246874|Cryomorphaceae	976|Bacteroidetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DTH2_k127_8236835_24	755732.Fluta_0165	8.523e-36	140.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
DTH2_k127_8236835_6	929556.Solca_3225	6.282e-125	412.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia	976|Bacteroidetes	EP	PFAM Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DTH2_k127_8236835_14	1454007.JAUG01000080_gene2269	3.255e-78	275.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_8236835_21	509635.N824_08685	2.177e-40	162.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_8236835_16	1270196.JCKI01000008_gene1302	3.384e-73	250.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DTH2_k127_8236835_19	203275.BFO_1032	8.53e-52	185.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia,22Y7E@171551|Porphyromonadaceae	976|Bacteroidetes	FG	HIT family hydrolase	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DTH2_k127_8236835_17	1121895.Q765_13340	1.386e-68	235.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia,2NS6N@237|Flavobacterium	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DTH2_k127_8236835_11	926562.Oweho_2867	1.19e-95	324.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1I8GR@117743|Flavobacteriia,2PAP2@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8236835_1	1408433.JHXV01000022_gene3142	5.067e-308	989.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8236835_0	1408433.JHXV01000020_gene3544	0.0	1035.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_8236835_26	1356852.N008_09850	3.786e-26	112.0	COG2146@1|root,COG2146@2|Bacteria,4NV1B@976|Bacteroidetes,47S5J@768503|Cytophagia	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8236835_3	1122621.ATZA01000009_gene261	7.364e-246	763.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,1IQTE@117747|Sphingobacteriia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH2_k127_8236835_15	796940.HMPREF9628_00326	2.31e-76	269.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia	186801|Clostridia	KLT	PFAM KWG Leptospira repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
DTH2_k127_8236835_13	269798.CHU_3825	1.664e-79	272.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
DTH2_k127_8236835_25	313606.M23134_00086	1.005e-28	123.0	COG0352@1|root,COG0352@2|Bacteria,4NRDR@976|Bacteroidetes,47RRW@768503|Cytophagia	976|Bacteroidetes	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
DTH2_k127_8236835_23	1124780.ANNU01000005_gene2440	4.856e-36	144.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,47R6S@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
DTH2_k127_8236835_20	926549.KI421517_gene185	1.24e-47	177.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,47QMU@768503|Cytophagia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
DTH2_k127_8236835_2	1123276.KB893246_gene712	2.354e-277	874.0	COG4206@1|root,COG4206@2|Bacteria,4PM93@976|Bacteroidetes,47YB2@768503|Cytophagia	976|Bacteroidetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8266959_2	153721.MYP_4029	3.021e-85	302.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
DTH2_k127_8266959_4	929556.Solca_3742	9.263e-75	261.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,1IRT8@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC-type phosphate transport system periplasmic	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_8266959_6	929556.Solca_3744	2.645e-58	212.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,1ISCX@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_8266959_7	755732.Fluta_1108	8.978e-50	184.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1I08G@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transporter ExbD	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
DTH2_k127_8266959_8	755732.Fluta_1107	3.012e-43	166.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,1I46Q@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transporter ExbD	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
DTH2_k127_8266959_3	755732.Fluta_1106	5.868e-79	271.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1HY7I@117743|Flavobacteriia	976|Bacteroidetes	U	Flagellar motor protein MotA	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_8266959_9	743722.Sph21_2758	5.845e-40	156.0	COG0586@1|root,COG0586@2|Bacteria,4NMBP@976|Bacteroidetes,1J08G@117747|Sphingobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH2_k127_8266959_5	714943.Mucpa_3116	2.881e-60	214.0	COG0586@1|root,COG0586@2|Bacteria,4NMBP@976|Bacteroidetes,1IRXI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH2_k127_8266959_0	1123277.KB893190_gene4924	5.471e-153	493.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
DTH2_k127_8266959_1	1123278.KB893559_gene3064	4.762e-110	367.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,47KJD@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH2_k127_8294033_0	1168034.FH5T_21195	3.084e-155	505.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,2G3GJ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_8294033_6	762903.Pedsa_1014	2.002e-12	70.0	2E35A@1|root,32Y59@2|Bacteria,4NVFH@976|Bacteroidetes,1IU6S@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8294033_2	153721.MYP_305	2.998e-97	322.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH2_k127_8294033_3	1270196.JCKI01000003_gene1967	5.168e-47	176.0	COG3208@1|root,COG3208@2|Bacteria,4PM28@976|Bacteroidetes,1J0JP@117747|Sphingobacteriia	976|Bacteroidetes	Q	Thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DTH2_k127_8294033_1	697282.Mettu_1995	7.826e-102	334.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1XDQ3@135618|Methylococcales	135618|Methylococcales	C	PFAM Inorganic pyrophosphatase	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
DTH2_k127_8294033_7	1250005.PHEL85_3326	4.854e-06	56.0	2CEJJ@1|root,3253Y@2|Bacteria,4NRTC@976|Bacteroidetes,1I2U7@117743|Flavobacteriia,3VWZ8@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8294033_4	746697.Aeqsu_0488	6.325e-43	164.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH2_k127_8306177_6	1408813.AYMG01000005_gene3214	5.464e-51	183.0	COG1670@1|root,COG1670@2|Bacteria,4PKMC@976|Bacteroidetes,1IQJ3@117747|Sphingobacteriia	976|Bacteroidetes	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_8306177_0	1150600.ADIARSV_2090	3.809e-180	572.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
DTH2_k127_8306177_4	1454007.JAUG01000096_gene195	3.42e-139	448.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1IPHE@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH2_k127_8306177_1	153721.MYP_1173	1.205e-170	542.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,47JQP@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_8306177_3	468059.AUHA01000002_gene616	6.109e-140	451.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1IQ2H@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH2_k127_8306177_5	926549.KI421517_gene3529	9.809e-89	300.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,47JI3@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_8306177_2	509635.N824_11910	1.998e-151	485.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DTH2_k127_8346294_0	1408433.JHXV01000029_gene3091	6.033e-131	426.0	COG0399@1|root,COG0399@2|Bacteria,4NEIU@976|Bacteroidetes,1HYAQ@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_8346294_1	1408433.JHXV01000029_gene3116	4.378e-122	398.0	COG0451@1|root,COG0451@2|Bacteria,4NH7Y@976|Bacteroidetes,1I0N9@117743|Flavobacteriia,2PBG0@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_8364536_2	991.IW20_23665	1.27e-51	189.0	COG1893@1|root,COG1893@2|Bacteria,4NMFF@976|Bacteroidetes,1I3H3@117743|Flavobacteriia,2NUQF@237|Flavobacterium	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DTH2_k127_8364536_5	755732.Fluta_2422	4.925e-19	93.0	29BEQ@1|root,2ZYD2@2|Bacteria,4PD0R@976|Bacteroidetes,1ICRX@117743|Flavobacteriia,2PBXT@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8364536_0	929703.KE386491_gene3311	1.817e-81	281.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,47MXF@768503|Cytophagia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
DTH2_k127_8364536_1	485917.Phep_0696	6.545e-71	247.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,1ISMP@117747|Sphingobacteriia	976|Bacteroidetes	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
DTH2_k127_8364536_4	762903.Pedsa_2475	5.354e-25	106.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IU1T@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
DTH2_k127_8364536_3	1237149.C900_00032	2.008e-29	124.0	COG2353@1|root,COG2911@1|root,COG2353@2|Bacteria,COG2911@2|Bacteria,4PMEU@976|Bacteroidetes,47RH2@768503|Cytophagia	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Laminin_G_3
DTH2_k127_839159_4	880071.Fleli_0676	2.451e-19	99.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_839159_3	391587.KAOT1_07858	5.547e-74	254.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1HX2Z@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH2_k127_839159_0	1408473.JHXO01000004_gene131	0.0	1328.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,2FNFZ@200643|Bacteroidia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
DTH2_k127_839159_1	468059.AUHA01000002_gene1372	1.525e-217	690.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1IQFU@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
DTH2_k127_839159_2	1380600.AUYN01000009_gene1691	2.476e-80	276.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
DTH2_k127_839159_5	1168034.FH5T_13690	5.415e-07	51.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_8414388_4	694427.Palpr_0078	5.365e-44	161.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,2FSAZ@200643|Bacteroidia,22Z2D@171551|Porphyromonadaceae	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_8414388_3	471854.Dfer_5793	1.314e-62	222.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_8414388_0	468059.AUHA01000002_gene1108	2.504e-305	944.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_8414388_5	1313301.AUGC01000009_gene995	1.483e-15	87.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH2_k127_8414388_1	313606.M23134_04089	7.155e-118	400.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,47MYA@768503|Cytophagia	976|Bacteroidetes	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
DTH2_k127_8414388_2	153721.MYP_1661	2.157e-76	263.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,47NYD@768503|Cytophagia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_8492269_1	153721.MYP_1744	2.097e-126	420.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
DTH2_k127_8492269_10	1121373.KB903629_gene382	0.0002173	53.0	COG3405@1|root,COG3794@1|root,COG3866@1|root,COG4886@1|root,COG3405@2|Bacteria,COG3794@2|Bacteria,COG3866@2|Bacteria,COG4886@2|Bacteria,4PMDJ@976|Bacteroidetes,47TS5@768503|Cytophagia	976|Bacteroidetes	CG	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
DTH2_k127_8492269_9	1094466.KQS_08765	1.199e-11	68.0	2E46C@1|root,32Z2A@2|Bacteria,4NV81@976|Bacteroidetes,1I537@117743|Flavobacteriia,2NXAP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8492269_4	880071.Fleli_1574	6.862e-53	194.0	COG3279@1|root,COG3279@2|Bacteria,4NHUZ@976|Bacteroidetes,47PSG@768503|Cytophagia	976|Bacteroidetes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH2_k127_8492269_0	313606.M23134_00789	2.728e-136	463.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HNOBA,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
DTH2_k127_8492269_2	1086011.HJ01_00981	2.419e-70	243.0	COG1060@1|root,COG1060@2|Bacteria,4PDXS@976|Bacteroidetes,1ICYV@117743|Flavobacteriia,2NW7K@237|Flavobacterium	976|Bacteroidetes	H	Haem-NO-binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
DTH2_k127_8492269_6	391598.FBBAL38_08205	1.014e-25	125.0	COG1345@1|root,COG4733@1|root,COG1345@2|Bacteria,COG4733@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia	976|Bacteroidetes	N	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CUB
DTH2_k127_8492269_5	1121898.Q766_05980	1.173e-36	161.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
DTH2_k127_8492269_8	1107311.Q767_15055	4.3e-14	87.0	COG3391@1|root,COG3391@2|Bacteria,4PPH2@976|Bacteroidetes,1IKMV@117743|Flavobacteriia,2NUGB@237|Flavobacterium	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HYR
DTH2_k127_8492269_3	1313421.JHBV01000031_gene1359	1.011e-58	206.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1IP50@117747|Sphingobacteriia	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
DTH2_k127_8499569_4	1120951.AUBG01000011_gene2469	1.515e-84	288.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
DTH2_k127_8499569_8	926549.KI421517_gene3841	6.94e-53	190.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47QSI@768503|Cytophagia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DTH2_k127_8499569_5	760192.Halhy_3288	5.255e-77	269.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Bacterial lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
DTH2_k127_8499569_10	926562.Oweho_1261	2.855e-05	51.0	COG2010@1|root,COG2010@2|Bacteria,4NVAQ@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8499569_0	1358423.N180_07070	1.793e-195	617.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DTH2_k127_8499569_7	1121373.KB903641_gene3706	2.74e-58	224.0	2C4MF@1|root,300D5@2|Bacteria,4NPEA@976|Bacteroidetes,47RYT@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8499569_9	153721.MYP_1564	1.694e-48	189.0	2F2AF@1|root,33V8E@2|Bacteria,4P2D9@976|Bacteroidetes,47USP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8499569_1	762903.Pedsa_1025	3.204e-125	406.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1IQ2W@117747|Sphingobacteriia	976|Bacteroidetes	M	2-dehydro-3-deoxyphosphooctonate aldolase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
DTH2_k127_8499569_3	515635.Dtur_1285	2.564e-86	304.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
DTH2_k127_8499569_6	1121373.KB903663_gene997	7.6e-60	224.0	COG1807@1|root,COG1807@2|Bacteria,4P3B3@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8499569_2	926549.KI421517_gene1020	1.841e-86	291.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,47JWX@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DTH2_k127_8521175_0	1121957.ATVL01000007_gene1905	1.222e-177	570.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
DTH2_k127_8521175_4	1408433.JHXV01000043_gene3000	2.052e-13	77.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_8
DTH2_k127_8521175_3	641107.CDLVIII_2780	9.213e-16	87.0	COG4870@1|root,COG4870@2|Bacteria,1V236@1239|Firmicutes,24HR0@186801|Clostridia,36JWW@31979|Clostridiaceae	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DTH2_k127_8521175_2	421072.IO89_05145	4.718e-128	414.0	COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,1HXEB@117743|Flavobacteriia,3HIPT@358033|Chryseobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH2_k127_8521175_1	1122621.ATZA01000012_gene3157	2.05e-137	456.0	COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,1IPQP@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4,ABC2_membrane_5,Peptidase_M1
DTH2_k127_8577741_6	926562.Oweho_1027	3.012e-52	186.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia,2PARZ@246874|Cryomorphaceae	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DTH2_k127_8577741_5	755732.Fluta_3599	2.506e-81	289.0	COG4188@1|root,COG4188@2|Bacteria,4P2MC@976|Bacteroidetes,1I8M4@117743|Flavobacteriia	976|Bacteroidetes	S	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase
DTH2_k127_8577741_0	929556.Solca_2077	0.0	1195.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH2_k127_8577741_2	929556.Solca_2087	2.201e-115	380.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,1IRSG@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_8577741_7	927658.AJUM01000034_gene118	3.552e-37	143.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,2FTI6@200643|Bacteroidia,3XK3K@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
DTH2_k127_8577741_1	468059.AUHA01000002_gene551	3.196e-163	518.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,1IRDN@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
DTH2_k127_8577741_3	1150600.ADIARSV_2432	1.112e-111	366.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH2_k127_8577741_8	247490.KSU1_C1155	6.511e-25	105.0	COG0775@1|root,COG0775@2|Bacteria,2J4NX@203682|Planctomycetes	203682|Planctomycetes	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
DTH2_k127_8588498_5	269798.CHU_2756	7.033e-26	109.0	COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,47S4Y@768503|Cytophagia	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_8588498_2	153721.MYP_496	1.326e-69	246.0	28KUQ@1|root,2ZABF@2|Bacteria,4NQM0@976|Bacteroidetes,47KN1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
DTH2_k127_8588498_4	857087.Metme_1189	6.065e-54	198.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	-	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_21,RrnaAD
DTH2_k127_8588498_1	929556.Solca_4257	3.173e-79	271.0	COG1216@1|root,COG1216@2|Bacteria,4NJ6R@976|Bacteroidetes,1INPV@117747|Sphingobacteriia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8588498_3	926549.KI421517_gene3887	4.798e-63	235.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,47MXC@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_8588498_6	1121930.AQXG01000006_gene777	1.018e-17	92.0	COG0457@1|root,COG0457@2|Bacteria,4NXQQ@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8588498_0	153721.MYP_2228	6.881e-310	983.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_8588652_3	926562.Oweho_1031	1.044e-47	186.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
DTH2_k127_8588652_0	1150600.ADIARSV_2610	1.849e-283	882.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH2_k127_8588652_4	153721.MYP_2132	1.881e-05	53.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4P1P3@976|Bacteroidetes,47THG@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
DTH2_k127_8588652_1	485918.Cpin_6916	1.23e-209	660.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DTH2_k127_8588652_2	1358423.N180_13145	4.036e-204	641.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1IP9V@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DTH2_k127_8596185_10	886379.AEWI01000146_gene3235	1.552e-38	156.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_8596185_5	1046627.BZARG_990	3.583e-71	250.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,1HY9B@117743|Flavobacteriia	976|Bacteroidetes	J	rna methyltransferase	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_8596185_12	1122164.JHWF01000012_gene2640	7.083e-17	90.0	28RCN@1|root,2ZDS1@2|Bacteria,1NGBU@1224|Proteobacteria,1SUS9@1236|Gammaproteobacteria,1JDBV@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
DTH2_k127_8596185_4	929556.Solca_3723	4.698e-86	290.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1INQF@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
DTH2_k127_8596185_1	755732.Fluta_3624	1.37e-262	817.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia,2PA7A@246874|Cryomorphaceae	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
DTH2_k127_8596185_2	485918.Cpin_6897	2.613e-189	602.0	COG2317@1|root,COG2317@2|Bacteria,4NK5Q@976|Bacteroidetes,1IVUK@117747|Sphingobacteriia	976|Bacteroidetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
DTH2_k127_8596185_11	91464.S7335_3236	8.027e-27	114.0	COG2363@1|root,COG2363@2|Bacteria,1G6TZ@1117|Cyanobacteria,1H194@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
DTH2_k127_8596185_3	1094466.KQS_13210	1.698e-161	519.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,1HXRS@117743|Flavobacteriia,2NSMP@237|Flavobacterium	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DTH2_k127_8596185_6	694427.Palpr_1792	4.15e-60	216.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,22Y0T@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
DTH2_k127_8596185_9	1124780.ANNU01000052_gene3581	4.054e-47	175.0	COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,47QUB@768503|Cytophagia	976|Bacteroidetes	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
DTH2_k127_8596185_7	714943.Mucpa_3239	1.477e-58	209.0	COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,1IRXR@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
DTH2_k127_8596185_14	869213.JCM21142_31044	2.63e-09	67.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes	976|Bacteroidetes	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_8596185_8	926549.KI421517_gene3311	1.169e-49	198.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_8596185_13	926549.KI421517_gene3853	7.215e-15	88.0	COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_8596185_0	929703.KE386491_gene1612	0.0	1294.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
DTH2_k127_8597912_2	869213.JCM21142_31278	3.748e-65	235.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NHSC@976|Bacteroidetes,47XEJ@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_8597912_0	1408473.JHXO01000004_gene269	6.206e-69	238.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DTH2_k127_8597912_4	886379.AEWI01000016_gene1522	1.552e-64	232.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,2FSPD@200643|Bacteroidia,3XIQE@558415|Marinilabiliaceae	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH2_k127_8597912_3	1380384.JADN01000003_gene655	9.516e-65	226.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
DTH2_k127_8597912_1	714943.Mucpa_5330	1.56e-67	238.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1IRXA@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
DTH2_k127_8597912_5	1121904.ARBP01000016_gene5289	2.054e-20	96.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
DTH2_k127_8607556_0	1123234.AUKI01000013_gene1584	1.816e-66	239.0	COG2885@1|root,COG2885@2|Bacteria,4NNT0@976|Bacteroidetes,1I214@117743|Flavobacteriia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_8615559_3	1408433.JHXV01000001_gene784	5.925e-75	267.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,1I7GW@117743|Flavobacteriia,2PAW4@246874|Cryomorphaceae	976|Bacteroidetes	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
DTH2_k127_8615559_1	391598.FBBAL38_03820	6.818e-149	479.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
DTH2_k127_8615559_2	1178825.ALIH01000008_gene809	1.59e-108	358.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
DTH2_k127_8615559_0	945713.IALB_0408	1.315e-181	576.0	COG0761@1|root,COG0761@2|Bacteria	2|Bacteria	IM	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
DTH2_k127_8615559_7	240016.ABIZ01000001_gene4878	1.827e-06	61.0	COG3209@1|root,COG3266@1|root,COG4782@1|root,COG3209@2|Bacteria,COG3266@2|Bacteria,COG4782@2|Bacteria,46S8F@74201|Verrucomicrobia,2IV48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
DTH2_k127_8615559_4	1267211.KI669560_gene2791	2.469e-69	244.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1IS3D@117747|Sphingobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
DTH2_k127_8615559_6	313595.P700755_002319	6.998e-09	61.0	COG2866@1|root,COG2866@2|Bacteria,4NSQP@976|Bacteroidetes,1IFTQ@117743|Flavobacteriia,4C4BU@83612|Psychroflexus	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8615559_5	926569.ANT_07880	3.124e-33	141.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
DTH2_k127_8622979_1	1408433.JHXV01000001_gene718	1.209e-85	293.0	COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,1IKDJ@117743|Flavobacteriia,2PACH@246874|Cryomorphaceae	976|Bacteroidetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_V_gamma,PDDEXK_1
DTH2_k127_8622979_2	1408433.JHXV01000001_gene719	1.505e-54	195.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia,2PAV5@246874|Cryomorphaceae	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH2_k127_8622979_0	1408433.JHXV01000001_gene720	2.943e-180	568.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1HY3S@117743|Flavobacteriia,2PAC2@246874|Cryomorphaceae	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DTH2_k127_8623482_2	1313301.AUGC01000010_gene928	2.764e-72	246.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_8623482_0	694427.Palpr_2925	1.411e-200	635.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia,22X3X@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
DTH2_k127_8623482_1	153721.MYP_3471	1.291e-80	282.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_8628197_0	929556.Solca_0395	1.246e-229	727.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DTH2_k127_8628197_5	1168289.AJKI01000025_gene1465	1.138e-07	59.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes,2G27E@200643|Bacteroidia,3XK8F@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8628197_4	755732.Fluta_3556	7.47e-37	150.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8628197_2	1313421.JHBV01000007_gene4280	2.196e-111	382.0	COG0729@1|root,COG0729@2|Bacteria,4PKYQ@976|Bacteroidetes,1IS7K@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
DTH2_k127_8628197_1	509635.N824_11365	8.492e-136	446.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1INWB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
DTH2_k127_8628197_3	926562.Oweho_1029	1.119e-52	198.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,1I8FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8655277_1	1158294.JOMI01000002_gene2798	4.39e-220	694.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,2FNB6@200643|Bacteroidia	976|Bacteroidetes	P	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_8655277_0	929556.Solca_1443	2.844e-268	844.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1IQ4I@117747|Sphingobacteriia	976|Bacteroidetes	EU	peptidase	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DTH2_k127_8655277_2	926562.Oweho_3015	6.554e-194	614.0	COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,2PB4N@246874|Cryomorphaceae	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DTH2_k127_8655277_3	236814.IX39_04305	1.035e-44	177.0	2A78Y@1|root,30W5G@2|Bacteria,4PCQW@976|Bacteroidetes,1ID9M@117743|Flavobacteriia,3ZT29@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8675342_4	929556.Solca_3731	7.817e-55	197.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1ISVB@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH2_k127_8675342_5	1111730.ATTM01000001_gene1392	4.033e-30	121.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1I39R@117743|Flavobacteriia,2NWNI@237|Flavobacterium	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH2_k127_8675342_0	468059.AUHA01000002_gene1094	7.075e-238	750.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
DTH2_k127_8675342_1	929556.Solca_3728	1.549e-136	449.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1IPJW@117747|Sphingobacteriia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
DTH2_k127_8675342_2	762903.Pedsa_2947	2.771e-109	369.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1IP5V@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH2_k127_8675342_3	1408433.JHXV01000005_gene2328	5.784e-79	270.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,1I19N@117743|Flavobacteriia	976|Bacteroidetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DTH2_k127_8676156_1	1168034.FH5T_21745	4.036e-75	263.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_8676156_2	1408473.JHXO01000007_gene788	5e-61	214.0	COG2176@1|root,COG2176@2|Bacteria,4PM8C@976|Bacteroidetes,2FW8F@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG type nucleases (URI domain)	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
DTH2_k127_8676156_0	641526.ADIWIN_3835	2.01e-80	276.0	COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,1IJGW@117743|Flavobacteriia	976|Bacteroidetes	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
DTH2_k127_8695638_4	1150600.ADIARSV_1895	8.24e-86	293.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH2_k127_8695638_0	929556.Solca_1727	0.0	1322.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH2_k127_8695638_8	1158294.JOMI01000001_gene1579	3.322e-16	91.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,2FNM2@200643|Bacteroidia	976|Bacteroidetes	N	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
DTH2_k127_8695638_1	755732.Fluta_1768	0.0	1011.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1HYDB@117743|Flavobacteriia,2PAJM@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_8695638_5	869213.JCM21142_3966	7.524e-62	223.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8695638_7	927658.AJUM01000047_gene2832	1.041e-16	86.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes,2G27E@200643|Bacteroidia,3XK8F@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8695638_3	755732.Fluta_1217	2.72e-137	462.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_8695638_6	153721.MYP_2520	2.12e-60	218.0	COG1028@1|root,COG1028@2|Bacteria,4NNJ9@976|Bacteroidetes,47Q7Q@768503|Cytophagia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	yueD	-	1.1.1.320	ko:K16216	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
DTH2_k127_8695638_2	468059.AUHA01000005_gene2591	4.658e-200	629.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1INVN@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
DTH2_k127_8739436_9	388467.A19Y_2100	1.847e-72	251.0	2DVXU@1|root,33XMN@2|Bacteria	2|Bacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_8739436_7	203124.Tery_0631	7.557e-94	321.0	COG0438@1|root,COG0438@2|Bacteria,1G4XB@1117|Cyanobacteria,1HE65@1150|Oscillatoriales	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8739436_3	398767.Glov_1525	1.591e-161	534.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,42QBQ@68525|delta/epsilon subdivisions,2WNMH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
DTH2_k127_8739436_6	153948.NAL212_2493	1.106e-98	352.0	COG0030@1|root,COG0030@2|Bacteria,1QWB8@1224|Proteobacteria	1224|Proteobacteria	J	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23
DTH2_k127_8739436_12	700598.Niako_5554	4.452e-61	220.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	wbxA	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8739436_10	1454007.JAUG01000023_gene1283	1.699e-70	252.0	COG0642@1|root,COG2205@2|Bacteria	1454007.JAUG01000023_gene1283|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8739436_2	762903.Pedsa_2036	5.272e-226	709.0	COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,1INQA@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
DTH2_k127_8739436_4	1408433.JHXV01000019_gene1916	9.27e-151	502.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IKD0@117743|Flavobacteriia,2PAFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8739436_15	1356852.N008_15325	4.574e-10	73.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,4NDZC@976|Bacteroidetes,47RJR@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_8739436_8	755732.Fluta_2021	5.095e-77	282.0	COG3291@1|root,COG3291@2|Bacteria,4PFQY@976|Bacteroidetes,1ICPB@117743|Flavobacteriia,2PBH6@246874|Cryomorphaceae	976|Bacteroidetes	S	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta
DTH2_k127_8739436_1	926549.KI421517_gene2150	5.682e-236	736.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_8739436_13	929556.Solca_3810	2.893e-49	192.0	COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,1IYK8@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
DTH2_k127_8739436_0	1137281.D778_02171	2.331e-241	764.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Glyco_hydro_127,Glyco_hydro_76,Thioredox_DsbH
DTH2_k127_8739436_16	748449.Halha_1541	0.0006003	51.0	COG3206@1|root,COG3209@1|root,COG3206@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,3WB1U@53433|Halanaerobiales	186801|Clostridia	M	YD repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
DTH2_k127_8739436_11	762903.Pedsa_1757	7.304e-69	240.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1IRWM@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_8739436_5	929556.Solca_0271	3.998e-128	423.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1IRGW@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
DTH2_k127_8778018_4	1168034.FH5T_06745	9.164e-30	121.0	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,2G3BA@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_8778018_2	153721.MYP_2443	6.008e-78	268.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,SAM_MT
DTH2_k127_8778018_0	1168034.FH5T_06740	6.291e-139	451.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,2FPWJ@200643|Bacteroidia	976|Bacteroidetes	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_8778018_1	997884.HMPREF1068_00541	2.633e-84	283.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,4AKX2@815|Bacteroidaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DTH2_k127_8778018_3	1408473.JHXO01000010_gene3763	1.376e-37	157.0	COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,2FQ6V@200643|Bacteroidia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
DTH2_k127_8810371_10	929556.Solca_1726	3.569e-05	48.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH2_k127_8810371_3	485917.Phep_1475	3.087e-115	386.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_8810371_4	714943.Mucpa_5350	3.585e-61	218.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH2_k127_8810371_7	1313421.JHBV01000039_gene2729	1.618e-19	105.0	COG3209@1|root,COG3291@1|root,COG4935@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NHWG@976|Bacteroidetes,1IRF4@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_8810371_8	755732.Fluta_0103	2.152e-19	104.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_2,CHU_C,PKD,SprB
DTH2_k127_8810371_11	945713.IALB_1186	0.0004977	53.0	COG5368@1|root,COG5368@2|Bacteria	2|Bacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3131,Glycoamylase
DTH2_k127_8810371_0	1408813.AYMG01000033_gene5270	4.183e-256	797.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH2_k127_8810371_1	1408433.JHXV01000027_gene3728	1.8e-209	691.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_8810371_6	1278311.AUAL01000017_gene273	4.968e-48	176.0	COG2153@1|root,COG2153@2|Bacteria,3WUTM@544448|Tenericutes	544448|Tenericutes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
DTH2_k127_8810371_9	742817.HMPREF9449_02788	2.137e-13	75.0	COG5652@1|root,COG5652@2|Bacteria,4PA3X@976|Bacteroidetes,2FVHF@200643|Bacteroidia	976|Bacteroidetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
DTH2_k127_8810371_5	927658.AJUM01000034_gene275	7.809e-55	194.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia,3XK47@558415|Marinilabiliaceae	976|Bacteroidetes	E	Glycine cleavage H-protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DTH2_k127_8810371_2	1408473.JHXO01000001_gene2295	3.334e-153	510.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
DTH2_k127_8826505_0	929703.KE386491_gene438	1.169e-319	987.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47JMW@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH2_k127_8826505_2	1450525.JATV01000007_gene1260	7.218e-161	509.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia,2NS9D@237|Flavobacterium	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH2_k127_8826505_3	1121481.AUAS01000013_gene4139	3.824e-93	312.0	COG0345@1|root,COG0345@2|Bacteria,4NGIG@976|Bacteroidetes,47MGF@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
DTH2_k127_8826505_1	929556.Solca_3559	9.576e-192	606.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
DTH2_k127_8865265_1	592029.DDD_0445	2.163e-82	277.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia,3HJUX@363408|Nonlabens	976|Bacteroidetes	D	ATPases associated with a variety of cellular activities	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DTH2_k127_8865265_0	926562.Oweho_0162	1.704e-116	392.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,2PAE6@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
DTH2_k127_8912717_0	929556.Solca_4271	4.727e-133	437.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_8912717_3	1232437.KL662016_gene1205	1.569e-102	339.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2X1YR@28221|Deltaproteobacteria,2MIYF@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
DTH2_k127_8912717_10	1408433.JHXV01000001_gene679	3.318e-17	92.0	29ZH4@1|root,30MGV@2|Bacteria,4PBQQ@976|Bacteroidetes,1ICQS@117743|Flavobacteriia,2PBTA@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_8912717_5	1408473.JHXO01000006_gene1089	7.599e-78	272.0	COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,2FMM9@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Cytoplasmic, score 8.96	gldB	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8912717_7	395494.Galf_1844	1.378e-43	161.0	2AGY9@1|root,3176X@2|Bacteria	2|Bacteria	S	Gliding motility-associated protein GldC	gldC	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8912717_1	755732.Fluta_2083	4.197e-125	422.0	COG3291@1|root,COG3291@2|Bacteria,4P4C7@976|Bacteroidetes	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_8912717_6	1408473.JHXO01000005_gene1520	1.804e-76	261.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,2FM4M@200643|Bacteroidia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
DTH2_k127_8912717_2	1550091.JROE01000008_gene3733	7.467e-125	406.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,1IPDS@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
DTH2_k127_8912717_4	1120965.AUBV01000010_gene2879	1.693e-99	332.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,47NUX@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_8912717_9	485918.Cpin_3659	4.762e-35	142.0	2DP10@1|root,3302V@2|Bacteria,4PMCJ@976|Bacteroidetes,1J0N4@117747|Sphingobacteriia	976|Bacteroidetes	S	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
DTH2_k127_8912717_8	485918.Cpin_3659	7.223e-36	143.0	2DP10@1|root,3302V@2|Bacteria,4PMCJ@976|Bacteroidetes,1J0N4@117747|Sphingobacteriia	976|Bacteroidetes	S	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
DTH2_k127_8913671_9	1408433.JHXV01000005_gene2290	0.0001351	46.0	COG1729@1|root,COG1729@2|Bacteria,4PMDU@976|Bacteroidetes,1IKE6@117743|Flavobacteriia,2PB2R@246874|Cryomorphaceae	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_8913671_8	991.IW20_16655	4.011e-09	59.0	2EH3X@1|root,33AVW@2|Bacteria,4NYC0@976|Bacteroidetes,1I6GU@117743|Flavobacteriia,2NXJM@237|Flavobacterium	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8913671_2	927658.AJUM01000037_gene2191	2.072e-71	250.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,2G24N@200643|Bacteroidia,3XJR5@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8913671_3	1237149.C900_02511	5.482e-51	188.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_8913671_4	926549.KI421517_gene3480	4.355e-46	179.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47KFS@768503|Cytophagia	976|Bacteroidetes	M	PFAM Peptidase family M23	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
DTH2_k127_8913671_1	714943.Mucpa_0954	2.135e-189	598.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1IPSR@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_8913671_7	1408433.JHXV01000033_gene1147	2.581e-15	81.0	2A96H@1|root,30YB5@2|Bacteria,4PC34@976|Bacteroidetes,1IMTJ@117743|Flavobacteriia,2PC4Z@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_8913671_5	376686.Fjoh_1722	4.986e-40	153.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I4Y6@117743|Flavobacteriia,2NVZ8@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_8913671_6	926562.Oweho_1037	1.983e-32	131.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_8913671_0	485917.Phep_1244	0.0	1054.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,1IPEY@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DTH2_k127_8945173_2	313606.M23134_05582	7.902e-136	446.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,47MY8@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_8945173_11	865937.Gilli_0938	3.158e-32	126.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1I3YG@117743|Flavobacteriia,2P6Z9@244698|Gillisia	976|Bacteroidetes	J	Ribosomal L28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
DTH2_k127_8945173_0	485918.Cpin_1221	1.684e-201	638.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1IR85@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM membrane bound O-acyl transferase MBOAT	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
DTH2_k127_8945173_5	1121904.ARBP01000015_gene229	1.067e-65	240.0	COG2755@1|root,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,47P2X@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
DTH2_k127_8945173_4	485918.Cpin_1219	2.701e-100	344.0	COG2755@1|root,COG2755@2|Bacteria,4NK39@976|Bacteroidetes,1IRWS@117747|Sphingobacteriia	976|Bacteroidetes	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
DTH2_k127_8945173_7	1521187.JPIM01000085_gene3414	2.123e-64	236.0	COG0545@1|root,COG0545@2|Bacteria,2GA7H@200795|Chloroflexi,3762K@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidylprolyl isomerase FKBP-type	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
DTH2_k127_8945173_12	1170562.Cal6303_0515	4.116e-30	134.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1HJH3@1161|Nostocales	1117|Cyanobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DTH2_k127_8945173_8	926549.KI421517_gene320	3.743e-59	217.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47KIJ@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
DTH2_k127_8945173_9	761193.Runsl_2379	4.457e-35	146.0	COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47KIJ@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
DTH2_k127_8945173_10	1408433.JHXV01000010_gene505	4.128e-34	138.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,1IC47@117743|Flavobacteriia,2PB8G@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
DTH2_k127_8945173_3	1380600.AUYN01000009_gene1800	9.993e-116	381.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1HX3D@117743|Flavobacteriia	976|Bacteroidetes	S	DHHA1 domain	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_8945173_6	1346330.M472_03240	1.396e-64	223.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DTH2_k127_8945173_1	945713.IALB_0281	1.433e-146	479.0	COG1468@1|root,COG1468@2|Bacteria	2|Bacteria	L	DNA catabolic process, exonucleolytic	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779,PDDEXK_1
DTH2_k127_8983630_0	1121904.ARBP01000028_gene1663	5.802e-123	402.0	COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,47JH0@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
DTH2_k127_8983630_1	485918.Cpin_6937	2.407e-108	366.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1IQGK@117747|Sphingobacteriia	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH2_k127_900153_5	1121859.KB890754_gene1006	1.301e-43	161.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
DTH2_k127_900153_1	1270196.JCKI01000003_gene1762	1.895e-272	843.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH2_k127_900153_9	153721.MYP_4787	3.989e-25	106.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,47S1U@768503|Cytophagia	976|Bacteroidetes	C	PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
DTH2_k127_900153_0	694427.Palpr_1259	2.338e-300	963.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,22XFT@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
DTH2_k127_900153_4	880071.Fleli_1586	1.14e-44	164.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,47QEV@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
DTH2_k127_900153_3	762903.Pedsa_2292	1.343e-47	174.0	COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1IRUM@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
DTH2_k127_900153_6	762968.HMPREF9441_02318	9.58e-42	154.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,2FT22@200643|Bacteroidia	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DTH2_k127_900153_7	269798.CHU_2591	6.678e-40	151.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DTH2_k127_900153_2	468059.AUHA01000002_gene108	7.963e-194	620.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DTH2_k127_900153_8	1166018.FAES_4794	1.887e-33	149.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,GSDH,Melibiase_2
DTH2_k127_9061173_10	929703.KE386491_gene2448	3.002e-71	243.0	COG2907@1|root,COG2907@2|Bacteria,4NKSM@976|Bacteroidetes	976|Bacteroidetes	S	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DTH2_k127_9061173_2	1408813.AYMG01000007_gene4335	4.39e-159	508.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
DTH2_k127_9061173_8	1408813.AYMG01000007_gene4334	1.832e-83	284.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes,1IYX0@117747|Sphingobacteriia	976|Bacteroidetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
DTH2_k127_9061173_6	485917.Phep_3484	1.976e-122	395.0	COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,1IQTJ@117747|Sphingobacteriia	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_9061173_11	1237149.C900_00956	1.298e-67	240.0	COG0589@1|root,COG0589@2|Bacteria,4NGG8@976|Bacteroidetes,47T99@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_9061173_3	1279009.ADICEAN_00643	3.978e-142	462.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,47NZK@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DTH2_k127_9061173_7	1492737.FEM08_18390	4.006e-97	319.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia,2NTPY@237|Flavobacterium	976|Bacteroidetes	FJ	tRNA hydroxylase	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
DTH2_k127_9061173_12	468059.AUHA01000003_gene1947	9.38e-32	128.0	COG0824@1|root,COG0824@2|Bacteria,4NQ3I@976|Bacteroidetes,1ITE5@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_9061173_0	468059.AUHA01000002_gene1152	8.717e-211	672.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,1IPH4@117747|Sphingobacteriia	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	cap5D	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
DTH2_k127_9061173_4	1279009.ADICEAN_03694	2.626e-141	455.0	COG0451@1|root,COG0451@2|Bacteria,4NKVH@976|Bacteroidetes,47TKC@768503|Cytophagia	976|Bacteroidetes	GM	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH2_k127_9061173_5	1313421.JHBV01000041_gene3497	3.47e-132	430.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH2_k127_9061173_1	485917.Phep_0406	2.972e-180	569.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DTH2_k127_9061173_9	1408433.JHXV01000021_gene1665	1.386e-71	249.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IMQY@117743|Flavobacteriia,2PBHE@246874|Cryomorphaceae	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
DTH2_k127_9061173_13	468059.AUHA01000002_gene29	2.377e-24	104.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
DTH2_k127_9082125_1	755732.Fluta_1488	1.298e-115	383.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_9082125_3	485918.Cpin_1115	1.212e-24	106.0	2DPXN@1|root,333U2@2|Bacteria,4NWCD@976|Bacteroidetes	976|Bacteroidetes	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
DTH2_k127_9082125_2	485918.Cpin_1235	1.682e-49	184.0	COG3063@1|root,COG3063@2|Bacteria,4PKEN@976|Bacteroidetes	976|Bacteroidetes	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9082125_0	485918.Cpin_1234	1.236e-221	708.0	COG4206@1|root,COG4206@2|Bacteria,4NGBJ@976|Bacteroidetes,1IP30@117747|Sphingobacteriia	976|Bacteroidetes	H	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_9084931_0	1434325.AZQN01000004_gene1553	3.233e-103	353.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_9084931_1	745718.JADT01000001_gene1810	2.642e-77	263.0	COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,1I1JP@117743|Flavobacteriia	976|Bacteroidetes	Q	SAM-dependent	tpm	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
DTH2_k127_9084931_2	468059.AUHA01000002_gene591	1.238e-39	153.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,1IRY7@117747|Sphingobacteriia	976|Bacteroidetes	M	Nlp p60 protein	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
DTH2_k127_9112185_11	886379.AEWI01000037_gene2996	6.915e-08	55.0	2DM48@1|root,31NG2@2|Bacteria,4NQJF@976|Bacteroidetes,2G27H@200643|Bacteroidia,3XK8I@558415|Marinilabiliaceae	976|Bacteroidetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
DTH2_k127_9112185_4	504487.JCM19302_3931	2.745e-76	260.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1HYH0@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH2_k127_9112185_3	929556.Solca_4292	2.658e-113	368.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DTH2_k127_9112185_9	468059.AUHA01000002_gene1129	9.243e-35	145.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9112185_1	929556.Solca_4039	4.154e-198	624.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DTH2_k127_9112185_5	1089547.KB913013_gene617	1.828e-66	235.0	COG1496@1|root,COG1496@2|Bacteria,4NM9H@976|Bacteroidetes,47JW0@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
DTH2_k127_9112185_0	1121904.ARBP01000003_gene6390	4.43e-276	854.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_9112185_6	984262.SGRA_2924	7.56e-47	173.0	COG1522@1|root,COG1522@2|Bacteria,4NMYA@976|Bacteroidetes,1IS24@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator, asnc family	-	-	-	ko:K03719,ko:K05800	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
DTH2_k127_9112185_7	929713.NIASO_15405	2.854e-42	158.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1IT89@117747|Sphingobacteriia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
DTH2_k127_9112185_8	1408254.T458_02855	1.758e-39	153.0	COG2928@1|root,COG2928@2|Bacteria,1VBFF@1239|Firmicutes,4HGH9@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
DTH2_k127_9112185_10	1408433.JHXV01000015_gene1768	5.028e-29	126.0	2A94C@1|root,30Y8F@2|Bacteria,4PBZT@976|Bacteroidetes,1ICRM@117743|Flavobacteriia,2PBWN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9112185_2	694427.Palpr_2054	7.421e-122	400.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,4NF7T@976|Bacteroidetes,2FKYE@200643|Bacteroidia,22WZ4@171551|Porphyromonadaceae	976|Bacteroidetes	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
DTH2_k127_9142878_1	755732.Fluta_1284	1.687e-123	409.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_9142878_5	755732.Fluta_1290	3.582e-32	134.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
DTH2_k127_9142878_2	1218108.KB908291_gene923	2.049e-114	374.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_9142878_3	468059.AUHA01000004_gene2351	6.714e-103	339.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,1IR7D@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_9142878_6	153721.MYP_2708	3.781e-22	98.0	COG0477@1|root,COG2814@2|Bacteria,4NUYS@976|Bacteroidetes,47S3H@768503|Cytophagia	976|Bacteroidetes	EGP	Domain of unknown function (DUF3817)	ydzA	-	-	-	-	-	-	-	-	-	-	-	DUF3817
DTH2_k127_9142878_0	714943.Mucpa_0527	4.041e-182	580.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,1IQWW@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase domain protein	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_9142878_4	755732.Fluta_2455	3.737e-50	180.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,2PAFP@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_9150771_6	1121101.HMPREF1532_00099	1.964e-09	59.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,2FM9K@200643|Bacteroidia,4AKKD@815|Bacteroidaceae	976|Bacteroidetes	DM	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
DTH2_k127_9150771_4	926562.Oweho_3393	6.755e-76	258.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia,2PATQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
DTH2_k127_9150771_3	755732.Fluta_2051	6.377e-77	270.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
DTH2_k127_9150771_2	926562.Oweho_3392	6.941e-99	334.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia,2PBKE@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Transglycosylase SLT domain	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
DTH2_k127_9150771_7	44454.NF84_04670	0.0003955	50.0	COG0739@1|root,COG0739@2|Bacteria,2GM7Q@201174|Actinobacteria,234FV@1762|Mycobacteriaceae	201174|Actinobacteria	M	peptidase	mepA	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
DTH2_k127_9150771_0	1250005.PHEL85_1161	0.0	1350.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia,3VWA4@52959|Polaribacter	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH2_k127_9150771_1	926549.KI421517_gene792	6.207e-111	362.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH2_k127_9150771_5	1408433.JHXV01000012_gene3975	1.225e-14	81.0	2ABBW@1|root,310SM@2|Bacteria,4PFE8@976|Bacteroidetes,1IG1J@117743|Flavobacteriia,2PBZZ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9172430_9	1121405.dsmv_1158	1.885e-39	161.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH2_k127_9172430_5	1168289.AJKI01000063_gene3445	9.304e-92	306.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,3XJ08@558415|Marinilabiliaceae	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_9172430_4	1121904.ARBP01000033_gene3216	4.279e-96	334.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_9172430_1	313606.M23134_00438	2.2e-245	764.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH2_k127_9172430_0	1313301.AUGC01000001_gene1456	1.808e-249	809.0	COG0747@1|root,COG4288@1|root,COG0747@2|Bacteria,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes	976|Bacteroidetes	E	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
DTH2_k127_9172430_3	700598.Niako_6049	2.204e-167	530.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1IQCT@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH2_k127_9172430_7	755732.Fluta_0117	6.558e-50	185.0	COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,1ICMW@117743|Flavobacteriia,2PAZM@246874|Cryomorphaceae	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_9172430_6	869213.JCM21142_1647	4.222e-76	262.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
DTH2_k127_9172430_8	385682.AFSL01000054_gene451	8.555e-43	169.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,2FSI2@200643|Bacteroidia,3XJZ7@558415|Marinilabiliaceae	976|Bacteroidetes	T	Prokaryotic dksA/traR C4-type zinc finger	yocK	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
DTH2_k127_9172430_2	929556.Solca_3313	1.763e-181	578.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1IPPT@117747|Sphingobacteriia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DTH2_k127_9241005_1	1123278.KB893546_gene4984	2.719e-12	67.0	COG0810@1|root,COG1629@1|root,COG4219@1|root,COG0810@2|Bacteria,COG1629@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,47M7Q@768503|Cytophagia	976|Bacteroidetes	KMT	PFAM BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C
DTH2_k127_9241005_0	153721.MYP_2785	1.503e-28	123.0	2FFF2@1|root,347CN@2|Bacteria	153721.MYP_2785|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9241005_2	1178825.ALIH01000014_gene1979	0.0007365	43.0	2DBVI@1|root,2ZBB6@2|Bacteria,4NE5V@976|Bacteroidetes,1I0JW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9243341_9	243164.DET0736	9.49e-30	122.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi,34CMA@301297|Dehalococcoidia	301297|Dehalococcoidia	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
DTH2_k127_9243341_0	468059.AUHA01000003_gene1712	0.0	1082.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1INV9@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH2_k127_9243341_7	700598.Niako_4028	2.92e-61	217.0	COG0778@1|root,COG0778@2|Bacteria,4NPZV@976|Bacteroidetes	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DTH2_k127_9243341_1	1313421.JHBV01000039_gene2785	8.023e-147	480.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,1IR01@117747|Sphingobacteriia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DTH2_k127_9243341_10	755732.Fluta_3196	1.246e-16	85.0	2EDGF@1|root,337CN@2|Bacteria,4NXB6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9243341_5	1123248.KB893316_gene4665	3.468e-94	314.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,1IWMK@117747|Sphingobacteriia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
DTH2_k127_9243341_2	1123248.KB893316_gene4664	1.781e-122	405.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH2_k127_9243341_4	1237149.C900_02165	1.407e-99	338.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH2_k127_9243341_3	468059.AUHA01000007_gene2663	8.741e-102	336.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IWQ3@117747|Sphingobacteriia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_9243341_6	946077.W5A_06446	6.152e-86	298.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1I95J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9243341_8	1150600.ADIARSV_1635	1.371e-56	214.0	COG0642@1|root,COG3290@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,4NG0Y@976|Bacteroidetes,1IPHZ@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DTH2_k127_9256848_5	1382306.JNIM01000001_gene2084	4.582e-44	185.0	COG2080@1|root,COG2080@2|Bacteria,2G8E9@200795|Chloroflexi	200795|Chloroflexi	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DTH2_k127_9256848_1	485913.Krac_2434	1.108e-204	669.0	COG1529@1|root,COG1529@2|Bacteria,2G5NF@200795|Chloroflexi	2|Bacteria	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DTH2_k127_9256848_4	485913.Krac_2435	1.045e-44	174.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
DTH2_k127_9256848_7	589924.Ferp_0688	0.0005324	49.0	COG3945@1|root,arCOG01471@2157|Archaea	2157|Archaea	S	Hemerythrin HHE cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
DTH2_k127_9256848_3	1123037.AUDE01000032_gene2266	6.684e-51	182.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1IJ7N@117743|Flavobacteriia	976|Bacteroidetes	C	ferredoxin	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
DTH2_k127_9256848_0	1267211.KI669560_gene2869	1.563e-263	825.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1IYHV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH2_k127_9256848_2	1123248.KB893348_gene118	8.826e-142	457.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_9256848_6	795359.TOPB45_0383	1.931e-12	74.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
DTH2_k127_9293949_1	1270196.JCKI01000011_gene4239	5.64e-91	302.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,1INZ4@117747|Sphingobacteriia	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
DTH2_k127_9293949_0	1408433.JHXV01000002_gene372	4.343e-151	483.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,1HWKX@117743|Flavobacteriia,2PA5Z@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_9317503_0	929556.Solca_2066	3.73e-93	314.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1IQ05@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
DTH2_k127_9317503_4	929556.Solca_1755	1.288e-60	213.0	COG1666@1|root,COG1666@2|Bacteria,4NMBZ@976|Bacteroidetes,1IRSS@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
DTH2_k127_9317503_6	1121889.AUDM01000013_gene1801	6.187e-45	166.0	2A94U@1|root,30Y94@2|Bacteria,4NP54@976|Bacteroidetes,1I2IQ@117743|Flavobacteriia,2NX8Z@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9317503_8	1122176.KB903552_gene3713	4.38e-30	123.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1ITVQ@117747|Sphingobacteriia	976|Bacteroidetes	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
DTH2_k127_9317503_1	1121373.KB903630_gene263	1.79e-80	274.0	COG1225@1|root,COG1225@2|Bacteria,4NXEC@976|Bacteroidetes	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9317503_10	1230342.CTM_09781	5.319e-09	69.0	COG4886@1|root,COG4886@2|Bacteria,1V3UH@1239|Firmicutes,24K2H@186801|Clostridia,36H00@31979|Clostridiaceae	186801|Clostridia	M	leucine-rich repeat-containing protein typical subtype	inlA	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,LRR_4,LRR_6,LRR_8,SLH
DTH2_k127_9317503_2	153721.MYP_168	7.499e-68	254.0	2DBC9@1|root,2Z8CA@2|Bacteria,4NJS4@976|Bacteroidetes,47QAH@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
DTH2_k127_9317503_5	1121373.KB903630_gene264	6.484e-59	208.0	2AQME@1|root,31FUG@2|Bacteria,4NRV3@976|Bacteroidetes,47VCI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9317503_9	153721.MYP_5022	3.689e-21	100.0	COG5031@1|root,COG5031@2|Bacteria	2|Bacteria	H	ubiquinone biosynthetic process	-	-	-	ko:K18586	-	-	-	-	ko00000	-	-	-	Coq4
DTH2_k127_9317503_7	269798.CHU_2579	4.715e-37	141.0	COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,47R9V@768503|Cytophagia	976|Bacteroidetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
DTH2_k127_9317503_3	153721.MYP_165	4.72e-65	228.0	COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,47P7G@768503|Cytophagia	976|Bacteroidetes	Q	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9331010_0	929556.Solca_1244	2.08e-160	509.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH2_k127_9331010_1	1094466.KQS_01415	2.168e-05	55.0	COG2849@1|root,COG2849@2|Bacteria,4NU55@976|Bacteroidetes,1I75R@117743|Flavobacteriia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_9350439_0	1408433.JHXV01000005_gene2532	6.126e-284	890.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia,2PAME@246874|Cryomorphaceae	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9372385_2	468059.AUHA01000003_gene1562	1.097e-110	367.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
DTH2_k127_9372385_4	1237149.C900_05211	1.408e-52	190.0	COG4430@1|root,COG4430@2|Bacteria,4NW07@976|Bacteroidetes,47RVU@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
DTH2_k127_9372385_5	1250006.JHZZ01000001_gene1961	7.85e-42	159.0	2CJVX@1|root,346Z6@2|Bacteria,4P6JP@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9372385_3	1250006.JHZZ01000001_gene1962	8.882e-98	333.0	2CJVW@1|root,33WUC@2|Bacteria,4P313@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9372385_0	1250006.JHZZ01000001_gene1964	3.072e-203	663.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K10110,ko:K19171	ko02010,map02010	M00194,M00221	-	-	ko00000,ko00001,ko00002,ko02000,ko02048	3.A.1.1.1,3.A.1.1.22,3.A.1.2	-	-	AAA_11,AAA_12,AAA_15,BPD_transp_2,MukB
DTH2_k127_9372385_6	391625.PPSIR1_00967	4.066e-06	54.0	2DN1Z@1|root,32V20@2|Bacteria,1Q8W3@1224|Proteobacteria,43E1M@68525|delta/epsilon subdivisions,2WZFP@28221|Deltaproteobacteria,2Z21B@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9372385_1	1121899.Q764_06935	3.967e-195	617.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,1HWYI@117743|Flavobacteriia,2NT12@237|Flavobacterium	976|Bacteroidetes	J	2-methylthioadenine synthetase	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
DTH2_k127_9375041_1	929556.Solca_4087	6.231e-160	513.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
DTH2_k127_9375041_0	762903.Pedsa_2873	7.471e-224	704.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
DTH2_k127_9375041_3	742767.HMPREF9456_00274	2.187e-44	165.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,2FS1V@200643|Bacteroidia,22XWD@171551|Porphyromonadaceae	976|Bacteroidetes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DTH2_k127_9375041_2	755732.Fluta_2594	3.125e-82	280.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia,2PAIE@246874|Cryomorphaceae	976|Bacteroidetes	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_946148_1	1408433.JHXV01000001_gene1082	2.984e-67	232.0	COG1595@1|root,COG1595@2|Bacteria,4NMJ7@976|Bacteroidetes,1I1YB@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_946148_0	1408433.JHXV01000001_gene1081	1.602e-271	845.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1HXQU@117743|Flavobacteriia,2PBAM@246874|Cryomorphaceae	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_9527533_2	926559.JoomaDRAFT_2454	2.122e-09	60.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1HY5K@117743|Flavobacteriia	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH2_k127_9527533_1	1250005.PHEL85_2258	2.024e-49	183.0	29X27@1|root,30IQN@2|Bacteria,4NSRX@976|Bacteroidetes,1I85G@117743|Flavobacteriia,3VWG3@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9527533_0	1408433.JHXV01000029_gene3073	9.784e-136	448.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
DTH2_k127_9553673_6	1122176.KB903544_gene801	2.049e-22	116.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1J19E@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,PKD,SprB
DTH2_k127_9553673_2	1094466.KQS_04005	2.093e-187	653.0	COG1345@1|root,COG1572@1|root,COG3291@1|root,COG4935@1|root,COG1345@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4PPGH@976|Bacteroidetes,1IKM5@117743|Flavobacteriia,2NW1I@237|Flavobacterium	976|Bacteroidetes	O	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9553673_0	755732.Fluta_3949	0.0	1064.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia,2PA6N@246874|Cryomorphaceae	976|Bacteroidetes	S	Glutamine synthetase type III N terminal	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
DTH2_k127_9553673_4	1408473.JHXO01000006_gene1037	1.636e-140	471.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_9553673_1	1450525.JATV01000006_gene1060	2.7e-205	643.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia,2NTHS@237|Flavobacterium	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_9553673_3	743722.Sph21_1449	1.102e-155	498.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_9553673_5	1453498.LG45_03155	2.145e-125	406.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,1HX31@117743|Flavobacteriia,2NSNX@237|Flavobacterium	976|Bacteroidetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DTH2_k127_9575475_7	1408473.JHXO01000005_gene1645	1.885e-31	126.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,2G3HG@200643|Bacteroidia	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
DTH2_k127_9575475_8	1122176.KB903576_gene5000	7.872e-12	72.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	2.8.1.1,2.8.1.2	ko:K01011,ko:K06867	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,Rhodanese
DTH2_k127_9575475_6	1453498.LG45_12160	7.231e-45	168.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia,2NUV3@237|Flavobacterium	976|Bacteroidetes	S	ABC transporter ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9575475_2	1408433.JHXV01000005_gene2527	8.27e-138	441.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia,2PAIT@246874|Cryomorphaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
DTH2_k127_9575475_5	1121895.Q765_00970	3.072e-71	242.0	COG0647@1|root,COG0647@2|Bacteria,4NNYH@976|Bacteroidetes,1I2FP@117743|Flavobacteriia,2NVYX@237|Flavobacterium	976|Bacteroidetes	G	Phosphoheptose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9575475_0	1121899.Q764_04940	1.571e-193	612.0	COG0247@1|root,COG0247@2|Bacteria,4PM9R@976|Bacteroidetes,1IJNY@117743|Flavobacteriia,2P0QQ@237|Flavobacterium	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
DTH2_k127_9575475_4	1358423.N180_12485	2.506e-71	252.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IQZY@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_9575475_3	999419.HMPREF1077_00469	9.575e-85	297.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,2FPGX@200643|Bacteroidia,22WFQ@171551|Porphyromonadaceae	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH2_k127_9575475_1	926562.Oweho_0211	2.06e-155	512.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1HXS2@117743|Flavobacteriia,2PAME@246874|Cryomorphaceae	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9828274_1	1349785.BAUG01000012_gene943	3.228e-149	479.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1I0MG@117743|Flavobacteriia	976|Bacteroidetes	M	COG2089 Sialic acid synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
DTH2_k127_9828274_2	411479.BACUNI_02982	4.087e-132	431.0	COG0027@1|root,COG0027@2|Bacteria	2|Bacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,CPSase_L_D2
DTH2_k127_9828274_8	710685.MycrhN_0303	9.904e-58	206.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	2.3.1.209,2.3.1.79	ko:K00661,ko:K21379	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
DTH2_k127_9828274_4	710685.MycrhN_0304	1.66e-113	375.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH2_k127_9828274_5	926561.KB900620_gene3029	1.762e-89	304.0	COG1621@1|root,COG1621@2|Bacteria,1V29W@1239|Firmicutes,24GDR@186801|Clostridia	186801|Clostridia	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9828274_7	243232.MJ_1062	1.417e-59	218.0	COG3980@1|root,arCOG06581@2157|Archaea,2XZ5T@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM acylneuraminate cytidylyltransferase	neuA	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3,Glyco_tran_28_C
DTH2_k127_9828274_6	216432.CA2559_13063	4.387e-83	282.0	COG1083@1|root,COG1083@2|Bacteria,4NM98@976|Bacteroidetes,1HXV6@117743|Flavobacteriia	976|Bacteroidetes	M	Cytidylyltransferase	pseF	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
DTH2_k127_9828274_0	411479.BACUNI_02986	4.173e-183	579.0	COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,2FMKJ@200643|Bacteroidia,4ANKY@815|Bacteroidaceae	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_9828274_3	1237149.C900_03564	4.883e-127	410.0	COG1086@1|root,COG1086@2|Bacteria,4NGN2@976|Bacteroidetes,47MCI@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
DTH2_k127_9828929_8	1506583.JQJY01000007_gene4257	3.533e-27	115.0	COG2005@1|root,COG2005@2|Bacteria,4NUSR@976|Bacteroidetes,1I5JR@117743|Flavobacteriia,2NWIF@237|Flavobacterium	976|Bacteroidetes	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
DTH2_k127_9828929_4	1120968.AUBX01000009_gene248	2.83e-44	166.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,47P9H@768503|Cytophagia	976|Bacteroidetes	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH2_k127_9828929_2	485918.Cpin_0678	4.619e-75	259.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_9828929_0	1124780.ANNU01000013_gene3877	0.0	1242.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47NQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_9828929_1	575590.HMPREF0156_00619	3.031e-82	280.0	COG0731@1|root,COG0731@2|Bacteria,4NJEM@976|Bacteroidetes	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_9828929_7	616991.JPOO01000003_gene1690	1.7e-32	130.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_9828929_5	1279009.ADICEAN_01196	3.938e-43	159.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,47M7C@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
DTH2_k127_9852446_11	1380384.JADN01000007_gene1520	6.291e-53	191.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1I2CB@117743|Flavobacteriia	976|Bacteroidetes	F	pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DTH2_k127_9852446_12	1158294.JOMI01000001_gene1515	8.531e-42	159.0	COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,2FM3K@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
DTH2_k127_9852446_16	1123070.KB899250_gene486	1.279e-12	74.0	2DZN5@1|root,32VEB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9852446_4	742766.HMPREF9455_03785	8.278e-103	344.0	COG0451@1|root,COG0451@2|Bacteria,4NEJJ@976|Bacteroidetes,2FNM5@200643|Bacteroidia,22W40@171551|Porphyromonadaceae	976|Bacteroidetes	GM	NAD dependent epimerase dehydratase family protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH2_k127_9852446_2	1304880.JAGB01000001_gene547	2.852e-116	386.0	COG0454@1|root,COG0456@2|Bacteria,1TT30@1239|Firmicutes,24DE0@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_9852446_1	1347393.HG726021_gene347	9.285e-165	526.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FM0N@200643|Bacteroidia,4AMI0@815|Bacteroidaceae	976|Bacteroidetes	E	Beta-eliminating lyase	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_9852446_14	1408473.JHXO01000002_gene3904	3.855e-23	104.0	2AU1F@1|root,31JMK@2|Bacteria,4NQUW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9852446_8	468059.AUHA01000003_gene1727	1.425e-81	276.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes,1IWGA@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2823 periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
DTH2_k127_9852446_6	468059.AUHA01000003_gene1727	2.123e-86	290.0	COG2823@1|root,COG2823@2|Bacteria,4NJ6H@976|Bacteroidetes,1IWGA@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2823 periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
DTH2_k127_9852446_15	990285.RGCCGE502_05679	4.873e-16	79.0	2E328@1|root,32Y2G@2|Bacteria,1PWUE@1224|Proteobacteria,2VEEU@28211|Alphaproteobacteria,4BKQN@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9852446_10	1123057.P872_07670	1.212e-62	222.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,47R4U@768503|Cytophagia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
DTH2_k127_9852446_9	1341181.FLJC2902T_02500	1.388e-65	231.0	COG1073@1|root,COG1073@2|Bacteria,4NMFG@976|Bacteroidetes,1I1R1@117743|Flavobacteriia,2NVP0@237|Flavobacterium	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
DTH2_k127_9852446_0	1123248.KB893316_gene4614	8.036e-185	592.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1IV2U@117747|Sphingobacteriia	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
DTH2_k127_9852446_5	1131812.JQMS01000001_gene1962	1.008e-87	301.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,4NK8R@976|Bacteroidetes,1I0Y1@117743|Flavobacteriia,2NY6Q@237|Flavobacterium	976|Bacteroidetes	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
DTH2_k127_9852446_7	1313421.JHBV01000043_gene3214	2.234e-85	293.0	COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes	976|Bacteroidetes	M	Bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
DTH2_k127_9852446_3	1237149.C900_03392	6.892e-106	355.0	COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,47M96@768503|Cytophagia	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
DTH2_k127_9852446_13	313596.RB2501_14329	2.334e-31	136.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1HY8U@117743|Flavobacteriia	976|Bacteroidetes	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH2_k127_9861469_2	634956.Geoth_2112	0.0007801	47.0	COG0454@1|root,COG0456@2|Bacteria,1VABX@1239|Firmicutes,4IS9Z@91061|Bacilli,1WGCR@129337|Geobacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
DTH2_k127_9861469_1	755732.Fluta_2605	1.66e-51	187.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,1I1ZU@117743|Flavobacteriia,2PB7Q@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802,ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DTH2_k127_9861469_0	1116472.MGMO_109c00050	1.22e-171	544.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XE5B@135618|Methylococcales	1236|Gammaproteobacteria	E	PFAM Aminotransferase, class I	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_9971191_0	1408433.JHXV01000029_gene3073	5.223e-141	479.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
DTH2_k127_9979699_2	153721.MYP_186	2.967e-164	532.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,47MVG@768503|Cytophagia	976|Bacteroidetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
DTH2_k127_9979699_3	1517682.HW49_02985	4.262e-98	333.0	COG2937@1|root,COG2937@2|Bacteria,4PMFA@976|Bacteroidetes,2G0YT@200643|Bacteroidia	976|Bacteroidetes	I	Belongs to the GPAT DAPAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_9979699_8	153721.MYP_190	3.52e-24	110.0	2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9979699_0	1121285.AUFK01000013_gene2527	0.0	1103.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia,3ZNRY@59732|Chryseobacterium	976|Bacteroidetes	CI	Phenylacetic acid degradation protein PaaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
DTH2_k127_9979699_4	755732.Fluta_2685	2.819e-88	314.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_9979699_6	755732.Fluta_1284	2.057e-43	176.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_9979699_5	1408433.JHXV01000015_gene1734	1.562e-65	231.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4P03T@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
DTH2_k127_9979699_1	755732.Fluta_1284	4.979e-165	543.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_9979699_7	391603.FBALC1_12742	2.341e-25	113.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
## 2785 queries scanned
## Total time (seconds): 78.64464473724365
## Rate: 35.41 q/s