## Mon Feb 16 12:10:09 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/DTH2_bin.57.fa -m mmseqs --output DTH2_bin.57 --output_dir /data/result/bins/wyx/eggqs50+/DTH2_bin.57 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DTH2_k127_10005796_1	468059.AUHA01000008_gene2791	2.764e-150	514.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPAB@117747|Sphingobacteriia	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
DTH2_k127_10005796_0	313606.M23134_04646	3.209e-153	490.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia	976|Bacteroidetes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_10005796_5	1123037.AUDE01000005_gene3021	1.025e-05	54.0	2E0P9@1|root,32W83@2|Bacteria,4NT81@976|Bacteroidetes,1I43E@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10005796_2	946077.W5A_06895	8.117e-113	366.0	COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1HXUY@117743|Flavobacteriia	976|Bacteroidetes	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DTH2_k127_10005796_4	313606.M23134_04663	1.417e-85	291.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,47M03@768503|Cytophagia	976|Bacteroidetes	P	Periplasmic binding protein	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
DTH2_k127_10005796_3	694427.Palpr_2430	2.436e-110	374.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,2FNEV@200643|Bacteroidia,22WBN@171551|Porphyromonadaceae	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_10011406_0	929556.Solca_1285	1.884e-183	602.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPM9@117747|Sphingobacteriia	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_10011406_1	313606.M23134_01115	7.038e-62	225.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,4NHRI@976|Bacteroidetes,47KP6@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_1001255_1	1121904.ARBP01000005_gene4844	5.852e-66	241.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47N2D@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
DTH2_k127_1001255_0	866536.Belba_2636	9.678e-199	632.0	COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,47K7E@768503|Cytophagia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
DTH2_k127_1001255_2	1239962.C943_03495	1.409e-11	64.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
DTH2_k127_1001933_2	468059.AUHA01000002_gene29	4.5e-103	342.0	28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,1IPV1@117747|Sphingobacteriia	976|Bacteroidetes	S	S1 P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
DTH2_k127_1001933_4	1158345.JNLL01000001_gene604	8.876e-49	179.0	COG0241@1|root,COG0241@2|Bacteria,2G469@200783|Aquificae	200783|Aquificae	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
DTH2_k127_1001933_3	984262.SGRA_3238	6.592e-53	194.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1IS8Q@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_1001933_1	926562.Oweho_0378	3.133e-129	439.0	COG2885@1|root,COG3063@1|root,COG2885@2|Bacteria,COG3063@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PA4T@246874|Cryomorphaceae	976|Bacteroidetes	M	OmpA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
DTH2_k127_1001933_0	929556.Solca_0511	1.388e-201	657.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IRAR@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
DTH2_k127_10050849_1	886293.Sinac_7570	1.512e-116	388.0	COG2242@1|root,COG2242@2|Bacteria,2J25Y@203682|Planctomycetes	203682|Planctomycetes	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10050849_4	886293.Sinac_7569	7.805e-38	160.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
DTH2_k127_10050849_0	1123248.KB893323_gene1595	1.186e-178	565.0	COG0451@1|root,COG0451@2|Bacteria,4NDX8@976|Bacteroidetes,1IWHA@117747|Sphingobacteriia	976|Bacteroidetes	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH2_k127_10050849_2	471854.Dfer_3836	5.524e-101	334.0	COG1215@1|root,COG1215@2|Bacteria,4NID9@976|Bacteroidetes,47M5U@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_10050849_3	1121904.ARBP01000001_gene5958	9.737e-94	313.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_1066023_2	1408433.JHXV01000001_gene721	7.613e-36	145.0	COG0457@1|root,COG0457@2|Bacteria,4PJHB@976|Bacteroidetes,1IMQ8@117743|Flavobacteriia,2PB7I@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_1066023_1	1121904.ARBP01000015_gene231	2.313e-39	154.0	2E469@1|root,32Z27@2|Bacteria,4P4UV@976|Bacteroidetes,47VHP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1066023_0	742766.HMPREF9455_01102	5.513e-82	289.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,2FPGX@200643|Bacteroidia,22WFQ@171551|Porphyromonadaceae	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH2_k127_1066023_3	468059.AUHA01000003_gene1777	5.63e-09	60.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_107762_2	1111732.AZOD01000033_gene741	0.0004827	43.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1X7HF@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH2_k127_107762_1	929556.Solca_2818	1.348e-129	419.0	COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,1IRFX@117747|Sphingobacteriia	976|Bacteroidetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH2_k127_107762_0	926562.Oweho_2340	2.69e-184	582.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia,2PAM6@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH2_k127_1087336_0	509635.N824_14750	9.366e-100	336.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1IQKA@117747|Sphingobacteriia	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
DTH2_k127_1087336_1	755732.Fluta_2041	2.166e-50	188.0	2EA9Q@1|root,334E4@2|Bacteria,4NX5I@976|Bacteroidetes,1IASC@117743|Flavobacteriia,2PB5U@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1092198_6	1449337.JQLL01000001_gene1668	2.691e-54	202.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	bioH	-	2.1.1.197,3.1.1.85,3.7.1.13,3.7.1.9,4.2.99.20	ko:K02169,ko:K02170,ko:K08680,ko:K10216,ko:K15756,ko:K16264	ko00130,ko00362,ko00621,ko00622,ko00643,ko00780,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map00621,map00622,map00643,map00780,map01100,map01110,map01120,map01220	M00116,M00544,M00569,M00572	R02604,R05362,R05365,R05865,R08166,R09543,R09725	RC00003,RC00272,RC00460,RC00461,RC00753,RC00754,RC00755,RC00757,RC01337,RC01485,RC02148,RC02475	br01602,ko00000,ko00001,ko00002,ko01000,ko02000	2.A.4.1	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
DTH2_k127_1092198_0	929556.Solca_1283	2.943e-194	612.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DTH2_k127_1092198_3	929562.Emtol_3738	4.212e-94	313.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,47JS7@768503|Cytophagia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH2_k127_1092198_7	1121904.ARBP01000017_gene5131	1.143e-27	123.0	2EBH5@1|root,335HP@2|Bacteria,4NW0F@976|Bacteroidetes,47VF8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1092198_1	1121129.KB903370_gene136	8.132e-156	496.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,2FPKZ@200643|Bacteroidia,22WD6@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DTH2_k127_1092198_2	509635.N824_21580	5.477e-123	403.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1INQV@117747|Sphingobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
DTH2_k127_1092198_5	906888.JCM19314_845	4.244e-66	235.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1HX11@117743|Flavobacteriia,3HJMV@363408|Nonlabens	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
DTH2_k127_1092198_4	1408433.JHXV01000034_gene8	4.732e-85	304.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
DTH2_k127_1092198_8	926562.Oweho_1991	5.694e-11	68.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_1118266_1	1131812.JQMS01000001_gene1830	1.628e-38	153.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1HY1D@117743|Flavobacteriia,2NSBS@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH2_k127_1118266_2	1408473.JHXO01000001_gene2345	4.348e-14	78.0	2EVWW@1|root,33PAJ@2|Bacteria,4NZKD@976|Bacteroidetes,2FZQQ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1118266_0	1408473.JHXO01000010_gene3654	4.097e-83	280.0	COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
DTH2_k127_1188068_10	1341155.FSS13T_00720	1.39e-55	209.0	2C80G@1|root,2Z7ZW@2|Bacteria,4NNAX@976|Bacteroidetes,1I0PF@117743|Flavobacteriia,2NSAP@237|Flavobacterium	976|Bacteroidetes	S	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
DTH2_k127_1188068_11	1120951.AUBG01000009_gene3001	6.986e-05	56.0	COG3391@1|root,COG3391@2|Bacteria,4NT0U@976|Bacteroidetes,1I43W@117743|Flavobacteriia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1188068_2	661478.OP10G_4157	2.1e-201	655.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
DTH2_k127_1188068_9	700598.Niako_3251	1.879e-78	278.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_1188068_6	485918.Cpin_0796	4.293e-150	481.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,1IWI9@117747|Sphingobacteriia	976|Bacteroidetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DTH2_k127_1188068_1	1434325.AZQN01000001_gene493	1.112e-259	823.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH2_k127_1188068_5	1506583.JQJY01000005_gene2344	5.516e-153	487.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1HWWH@117743|Flavobacteriia,2NS8M@237|Flavobacterium	976|Bacteroidetes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_1188068_7	1408433.JHXV01000029_gene3116	2.262e-123	402.0	COG0451@1|root,COG0451@2|Bacteria,4NH7Y@976|Bacteroidetes,1I0N9@117743|Flavobacteriia,2PBG0@246874|Cryomorphaceae	976|Bacteroidetes	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_1188068_8	929556.Solca_1217	5.451e-102	341.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,1INSC@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH2_k127_1188068_0	1408433.JHXV01000028_gene2161	7.404e-298	923.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1HYG5@117743|Flavobacteriia,2PAGZ@246874|Cryomorphaceae	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH2_k127_1188068_4	755732.Fluta_1367	9.601e-157	511.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH2_k127_1188068_3	1313421.JHBV01000041_gene3707	1.222e-200	650.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
DTH2_k127_1221462_4	1121129.KB903360_gene3385	6.09e-40	151.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,2FNAU@200643|Bacteroidia,22W8Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Penicillin-binding Protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DTH2_k127_1221462_1	929556.Solca_2021	7.639e-121	391.0	COG1788@1|root,COG1788@2|Bacteria,4NF3T@976|Bacteroidetes,1IQP0@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoA	-	2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9	ko:K01027,ko:K01028,ko:K01031,ko:K01034	ko00072,ko00280,ko00310,ko00362,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00362,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R02990,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DTH2_k127_1221462_0	468059.AUHA01000005_gene2577	6.773e-121	390.0	COG2057@1|root,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IQBC@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Coenzyme A transferase	scoB	-	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
DTH2_k127_1221462_2	760192.Halhy_5351	1.095e-78	286.0	COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1221462_3	1313421.JHBV01000025_gene1037	8.967e-61	214.0	COG2227@1|root,COG2227@2|Bacteria,4NJXV@976|Bacteroidetes	976|Bacteroidetes	H	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23
DTH2_k127_13391_2	509635.N824_03480	2.229e-43	160.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DTH2_k127_13391_5	1121373.KB903643_gene3581	4.207e-05	51.0	2E7ZI@1|root,333DR@2|Bacteria,4NVT6@976|Bacteroidetes,47VSZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_13391_4	485918.Cpin_6577	2.549e-14	78.0	2EWYR@1|root,346M6@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
DTH2_k127_13391_0	714943.Mucpa_2740	4.777e-156	502.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_13391_3	714943.Mucpa_2741	1.587e-42	159.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ISTA@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family UPF0079, ATPase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DTH2_k127_13391_1	215803.DB30_4950	9.049e-99	338.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
DTH2_k127_1367036_1	616991.JPOO01000003_gene1690	2.353e-53	191.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_1367036_0	1124780.ANNU01000013_gene3830	5.435e-140	450.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,47M7C@768503|Cytophagia	976|Bacteroidetes	H	Molybdenum cofactor biosynthesis protein	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
DTH2_k127_1367036_2	1408433.JHXV01000001_gene741	3.135e-50	181.0	COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,1I24D@117743|Flavobacteriia	976|Bacteroidetes	H	Molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
DTH2_k127_141178_3	755732.Fluta_1833	5.04e-36	147.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	AhpC-TSA,Omp28
DTH2_k127_141178_2	1408433.JHXV01000019_gene1917	5.542e-87	306.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_141178_1	1237149.C900_04898	4.609e-102	340.0	COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Succinylglutamate desuccinylase Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
DTH2_k127_141178_0	1121011.AUCB01000006_gene998	1.542e-129	419.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,1HZ04@117743|Flavobacteriia,23I6Q@178469|Arenibacter	976|Bacteroidetes	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
DTH2_k127_1503061_6	929562.Emtol_2688	1.236e-41	155.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,47MZD@768503|Cytophagia	976|Bacteroidetes	L	Caulimovirus viroplasmin	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
DTH2_k127_1503061_0	929556.Solca_4345	2.075e-183	585.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IQR9@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH2_k127_1503061_7	688270.Celal_1590	2.581e-16	79.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,1I54R@117743|Flavobacteriia,1F9NS@104264|Cellulophaga	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_1503061_5	1237149.C900_01020	1.538e-44	168.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia	976|Bacteroidetes	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
DTH2_k127_1503061_2	880071.Fleli_1871	1.679e-100	333.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,47M8B@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
DTH2_k127_1503061_1	306264.CUP0619	1.329e-108	361.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2YMCK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
DTH2_k127_1503061_3	762903.Pedsa_0771	2.454e-73	252.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1IRH8@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
DTH2_k127_1503061_4	929556.Solca_1917	1.576e-48	174.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DTH2_k127_1503974_0	485918.Cpin_0233	3.448e-95	321.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
DTH2_k127_1503974_2	485918.Cpin_1516	6.129e-07	61.0	COG3827@1|root,COG3827@2|Bacteria,4PKT6@976|Bacteroidetes,1J0M3@117747|Sphingobacteriia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1503974_1	313606.M23134_04150	6.18e-54	201.0	COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,47NIK@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_1523504_1	485917.Phep_3607	2.826e-137	441.0	COG1884@1|root,COG1884@2|Bacteria,4PN0H@976|Bacteroidetes,1IPCT@117747|Sphingobacteriia	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DTH2_k127_1523504_4	1279009.ADICEAN_02764	5.53e-29	124.0	28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1523504_0	468059.AUHA01000003_gene1988	9.781e-165	526.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1INY0@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_1523504_2	929556.Solca_2092	1.618e-102	343.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
DTH2_k127_1523504_3	153721.MYP_249	1.211e-81	279.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DTH2_k127_1557786_4	1122621.ATZA01000024_gene2157	2.634e-22	99.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1IR9R@117747|Sphingobacteriia	976|Bacteroidetes	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DTH2_k127_1557786_3	289376.THEYE_A0050	8.012e-29	118.0	COG2005@1|root,COG2005@2|Bacteria	2|Bacteria	P	Transcriptional regulator	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1
DTH2_k127_1557786_5	573413.Spirs_2389	1.928e-20	94.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK,RadC
DTH2_k127_1557786_1	1123248.KB893314_gene3277	1.893e-78	269.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1IRF7@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_1557786_2	1124780.ANNU01000013_gene3834	9.74e-37	146.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,47RE8@768503|Cytophagia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DTH2_k127_1557786_6	1120966.AUBU01000001_gene1090	8.473e-11	64.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DTH2_k127_1557786_0	1443665.JACA01000001_gene2592	1.977e-107	358.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,1HYQ3@117743|Flavobacteriia,2YHYZ@290174|Aquimarina	976|Bacteroidetes	H	ThiF family	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
DTH2_k127_158040_1	929556.Solca_2431	1.007e-108	360.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,1IPT6@117747|Sphingobacteriia	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
DTH2_k127_158040_0	1237149.C900_01568	1.457e-126	413.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_158040_2	1121930.AQXG01000001_gene1391	6.653e-77	263.0	COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes	976|Bacteroidetes	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
DTH2_k127_158040_3	1408473.JHXO01000010_gene3503	2.248e-28	115.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,2FMKR@200643|Bacteroidia	976|Bacteroidetes	L	TIGR02757 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
DTH2_k127_158061_2	709991.Odosp_0594	4.975e-62	218.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,2FN06@200643|Bacteroidia,22VUX@171551|Porphyromonadaceae	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_158061_3	869213.JCM21142_3966	1.264e-36	150.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_158061_1	929562.Emtol_1449	2.618e-209	665.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,47K61@768503|Cytophagia	976|Bacteroidetes	I	AMP-binding enzyme	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_158061_0	714943.Mucpa_2200	1.51e-239	748.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
DTH2_k127_1621655_4	1408433.JHXV01000028_gene2125	7.739e-57	211.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBC5@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_16,TPR_8
DTH2_k127_1621655_1	929556.Solca_0780	1.472e-148	480.0	COG1104@1|root,COG1104@2|Bacteria,4NG58@976|Bacteroidetes,1IQ14@117747|Sphingobacteriia	976|Bacteroidetes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH2_k127_1621655_5	1158294.JOMI01000002_gene2791	2.052e-55	196.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DTH2_k127_1621655_2	929556.Solca_2817	5.061e-102	337.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1IP0Y@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	metN	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH2_k127_1621655_3	1211813.CAPH01000012_gene329	2.314e-84	286.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,2FNVR@200643|Bacteroidia,22U8J@171550|Rikenellaceae	976|Bacteroidetes	Q	Permease MlaE	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH2_k127_1621655_7	929556.Solca_4353	7.812e-21	94.0	COG1918@1|root,COG1918@2|Bacteria,4P9Q5@976|Bacteroidetes,1ITZ3@117747|Sphingobacteriia	976|Bacteroidetes	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
DTH2_k127_1621655_0	153721.MYP_1792	6.776e-211	676.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
DTH2_k127_1621655_6	1454007.JAUG01000001_gene3683	4.173e-46	175.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,1IS5M@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
DTH2_k127_164395_3	504472.Slin_0522	5.065e-73	249.0	COG1187@1|root,COG1187@2|Bacteria,4NM4U@976|Bacteroidetes,47PFZ@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH2_k127_164395_5	1313421.JHBV01000049_gene108	1.543e-30	137.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_164395_8	760192.Halhy_6234	5.055e-15	90.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NS69@976|Bacteroidetes,1IT0V@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_164395_4	926562.Oweho_3290	1.494e-61	243.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_164395_7	1189612.A33Q_2245	1.789e-23	101.0	COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_164395_2	1121405.dsmv_3077	1.642e-73	265.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Beta_helix,SBBP
DTH2_k127_164395_1	927658.AJUM01000034_gene446	3.636e-93	317.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,2FS6N@200643|Bacteroidia,3XJ7C@558415|Marinilabiliaceae	976|Bacteroidetes	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
DTH2_k127_164395_0	1237149.C900_00016	8.594e-206	649.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
DTH2_k127_164395_6	1501230.ET33_00185	1.203e-28	118.0	COG0477@1|root,COG2814@2|Bacteria,1VGN4@1239|Firmicutes,4HNVP@91061|Bacilli,26ZUW@186822|Paenibacillaceae	91061|Bacilli	EGP	Domain of unknown function (DUF3817)	ydzA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3817
DTH2_k127_1698780_7	1386089.N865_15565	5.117e-17	91.0	COG0454@1|root,COG0456@2|Bacteria,2IQZI@201174|Actinobacteria	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_1698780_2	880071.Fleli_1536	2.604e-106	353.0	COG0463@1|root,COG0463@2|Bacteria,4NGGM@976|Bacteroidetes,47KIR@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
DTH2_k127_1698780_0	32057.KB217478_gene1822	1.083e-137	447.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wgaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
DTH2_k127_1698780_5	886379.AEWI01000052_gene2670	1.294e-57	215.0	COG0438@1|root,COG0438@2|Bacteria,4NZMT@976|Bacteroidetes,2G1JS@200643|Bacteroidia,3XKI2@558415|Marinilabiliaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
DTH2_k127_1698780_1	1250006.JHZZ01000001_gene2284	3.362e-118	390.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,3VWNZ@52959|Polaribacter	976|Bacteroidetes	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DTH2_k127_1698780_4	869213.JCM21142_31042	2.185e-70	243.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,47PE9@768503|Cytophagia	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DTH2_k127_1698780_3	1336803.PHEL49_0591	1.361e-97	330.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1HXXI@117743|Flavobacteriia,3VV4W@52959|Polaribacter	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DTH2_k127_1698780_6	869213.JCM21142_31186	1.324e-49	186.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia	976|Bacteroidetes	S	PFAM PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
DTH2_k127_170506_0	411154.GFO_2966	2.007e-145	470.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
DTH2_k127_170506_2	1408813.AYMG01000028_gene2452	1.378e-24	109.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1IUKR@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_170506_1	929703.KE386491_gene799	1.221e-76	261.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_1794324_5	1131812.JQMS01000001_gene1807	4.426e-43	163.0	2C6BU@1|root,32S87@2|Bacteria,4NRX1@976|Bacteroidetes,1I6S7@117743|Flavobacteriia,2NYWP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1794324_3	700598.Niako_4028	1.395e-69	241.0	COG0778@1|root,COG0778@2|Bacteria,4NPZV@976|Bacteroidetes	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DTH2_k127_1794324_2	1123057.P872_07670	1.871e-80	273.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,47R4U@768503|Cytophagia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
DTH2_k127_1794324_6	1492737.FEM08_35000	2.265e-11	64.0	2AF0Z@1|root,314Z9@2|Bacteria,4P7CF@976|Bacteroidetes,1IAXW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1794324_1	1123057.P872_07665	9.267e-84	282.0	COG1073@1|root,COG1073@2|Bacteria,4NMFG@976|Bacteroidetes,47QYJ@768503|Cytophagia	976|Bacteroidetes	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
DTH2_k127_1794324_7	925409.KI911562_gene1726	9.58e-05	51.0	2CBQ4@1|root,33DR4@2|Bacteria,4NZ1W@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1794324_4	925409.KI911562_gene2540	1.5e-45	179.0	COG1503@1|root,COG1503@2|Bacteria,4PGZN@976|Bacteroidetes,1IUTV@117747|Sphingobacteriia	976|Bacteroidetes	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1794324_0	1131812.JQMS01000001_gene323	2.262e-206	649.0	COG2312@1|root,COG2312@2|Bacteria,4NF9R@976|Bacteroidetes,1I4ES@117743|Flavobacteriia,2NXTG@237|Flavobacterium	976|Bacteroidetes	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
DTH2_k127_1800522_8	869213.JCM21142_93780	5.415e-14	74.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
DTH2_k127_1800522_2	435591.BDI_2025	8.23e-115	384.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,2FMHC@200643|Bacteroidia,22WJ1@171551|Porphyromonadaceae	976|Bacteroidetes	M	ABC transporter permease	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_1800522_1	926562.Oweho_0908	4.23e-137	451.0	COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia,2PA75@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
DTH2_k127_1800522_4	755732.Fluta_0615	1.422e-75	259.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IMPU@117743|Flavobacteriia,2PATN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1800522_7	289376.THEYE_A0027	3.776e-33	132.0	2DN1R@1|root,32V06@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF2703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
DTH2_k127_1800522_6	929556.Solca_2089	3.397e-45	169.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1ISSM@117747|Sphingobacteriia	976|Bacteroidetes	F	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_1800522_3	1144313.PMI10_02824	2.553e-84	286.0	COG1738@1|root,COG1738@2|Bacteria,4NNPU@976|Bacteroidetes,1I2GG@117743|Flavobacteriia,2NU67@237|Flavobacterium	976|Bacteroidetes	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
DTH2_k127_1800522_5	1408433.JHXV01000001_gene692	2.632e-51	193.0	COG2067@1|root,COG2067@2|Bacteria,4PKQK@976|Bacteroidetes	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1800522_0	929556.Solca_3749	1.176e-245	769.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
DTH2_k127_1808675_10	1136138.JH604622_gene424	3.561e-10	71.0	COG3391@1|root,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,1S21Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,Phosphoesterase
DTH2_k127_1808675_1	1484460.JSWG01000008_gene1892	1.286e-136	454.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH2_k127_1808675_8	1121897.AUGO01000003_gene1875	1.855e-22	101.0	COG2608@1|root,COG2608@2|Bacteria,4PPKN@976|Bacteroidetes,1IN4F@117743|Flavobacteriia,2P0SY@237|Flavobacterium	976|Bacteroidetes	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
DTH2_k127_1808675_4	700598.Niako_0883	8.397e-42	176.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1IWYM@117747|Sphingobacteriia	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
DTH2_k127_1808675_2	1313421.JHBV01000034_gene1693	2.211e-76	283.0	COG3227@1|root,COG3391@1|root,COG3227@2|Bacteria,COG3391@2|Bacteria,4P12F@976|Bacteroidetes	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1808675_9	388413.ALPR1_20408	4.375e-12	78.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia	976|Bacteroidetes	MU	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
DTH2_k127_1808675_0	485918.Cpin_1656	1.618e-157	501.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1IP11@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH2_k127_1808675_7	1122621.ATZA01000002_gene1602	1.015e-25	111.0	COG3577@1|root,COG3577@2|Bacteria,4PGFR@976|Bacteroidetes,1ITP7@117747|Sphingobacteriia	976|Bacteroidetes	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
DTH2_k127_1808675_5	746697.Aeqsu_2728	1.008e-40	154.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia	976|Bacteroidetes	S	Thiol-disulfide oxidoreductase	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
DTH2_k127_1808675_11	926560.KE387025_gene3984	3.161e-09	69.0	COG3391@1|root,COG3391@2|Bacteria,1WMPF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
DTH2_k127_1808675_3	1279009.ADICEAN_01203	2.48e-52	194.0	COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia	976|Bacteroidetes	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
DTH2_k127_1808675_6	1121373.KB903634_gene708	5.145e-29	123.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_1849048_2	984262.SGRA_4206	1.29e-21	109.0	COG4935@1|root,COG4935@2|Bacteria,4P0CG@976|Bacteroidetes	976|Bacteroidetes	O	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,PKD,P_proprotein
DTH2_k127_1849048_1	1408433.JHXV01000020_gene3539	1.939e-73	267.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	nanM	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
DTH2_k127_1849048_0	1408433.JHXV01000005_gene2361	1.846e-97	332.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1HY2Q@117743|Flavobacteriia,2PBZ4@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_3,Kelch_4,Kelch_6
DTH2_k127_1849048_4	525373.HMPREF0766_11851	4.129e-05	48.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	nanM	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
DTH2_k127_1919051_0	760192.Halhy_3205	1.632e-284	885.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,1INTV@117747|Sphingobacteriia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
DTH2_k127_1926441_1	1237149.C900_02885	4.899e-112	368.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
DTH2_k127_1926441_3	929556.Solca_3462	3.441e-76	259.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1IS2D@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_1926441_4	1202532.FF52_19380	3.803e-49	178.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia,2NW8V@237|Flavobacterium	976|Bacteroidetes	S	Transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_1926441_8	700598.Niako_5416	2.705e-05	47.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IW8Y@117747|Sphingobacteriia	976|Bacteroidetes	L	resolvase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH2_k127_1926441_0	313606.M23134_00438	2.878e-231	723.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH2_k127_1926441_7	402612.FP0232	2.307e-07	62.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NMA6@976|Bacteroidetes,1IJ6Q@117743|Flavobacteriia,2P0JV@237|Flavobacterium	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,Peptidase_M43
DTH2_k127_1926441_2	1121904.ARBP01000033_gene3216	1.25e-103	355.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_1926441_5	1236497.BAJQ01000005_gene1088	1.972e-11	66.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulatory protein	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_1963214_7	641143.HMPREF9331_00234	5.589e-08	60.0	COG3209@1|root,COG3209@2|Bacteria,4PECV@976|Bacteroidetes,1IEW5@117743|Flavobacteriia,1ERDX@1016|Capnocytophaga	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1963214_3	1123248.KB893321_gene517	2.697e-49	184.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISKV@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DTH2_k127_1963214_4	1121904.ARBP01000006_gene3985	2.931e-45	166.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,47QDB@768503|Cytophagia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
DTH2_k127_1963214_6	1270193.JARP01000003_gene2232	3.099e-18	89.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,1I52P@117743|Flavobacteriia,2NX63@237|Flavobacterium	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
DTH2_k127_1963214_2	742817.HMPREF9449_00743	1.039e-59	213.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,2FNF1@200643|Bacteroidia,22X5B@171551|Porphyromonadaceae	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DTH2_k127_1963214_0	925409.KI911562_gene2088	2.258e-308	957.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
DTH2_k127_1963214_1	1144275.COCOR_04108	3.481e-81	276.0	COG2085@1|root,COG2085@2|Bacteria,1NF95@1224|Proteobacteria,4380B@68525|delta/epsilon subdivisions,2X3AC@28221|Deltaproteobacteria,2YURK@29|Myxococcales	28221|Deltaproteobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
DTH2_k127_1963214_5	468059.AUHA01000002_gene261	3.333e-24	102.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_1974929_2	1346330.M472_22195	5.393e-82	282.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
DTH2_k127_1974929_0	761193.Runsl_1103	3.934e-205	647.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,47KR9@768503|Cytophagia	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_1974929_1	468059.AUHA01000006_gene3046	5.904e-158	505.0	COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,1INRF@117747|Sphingobacteriia	976|Bacteroidetes	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH2_k127_1974929_3	755732.Fluta_1284	1.292e-11	71.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_1976669_10	1121895.Q765_02825	3.613e-39	147.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia,2NW0E@237|Flavobacterium	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
DTH2_k127_1976669_11	1237149.C900_02814	1.822e-35	136.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,47R69@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DTH2_k127_1976669_1	929556.Solca_3281	9.209e-192	606.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DTH2_k127_1976669_5	1150600.ADIARSV_2076	2.965e-82	276.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,1IRJQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
DTH2_k127_1976669_0	926562.Oweho_1786	1.167e-239	751.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1HXWB@117743|Flavobacteriia,2PAJ9@246874|Cryomorphaceae	976|Bacteroidetes	O	Lon protease (S16) C-terminal proteolytic domain	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH2_k127_1976669_13	1408433.JHXV01000009_gene1308	7.086e-07	58.0	2BV1Q@1|root,32QEG@2|Bacteria,4PC2J@976|Bacteroidetes,1ICTI@117743|Flavobacteriia,2PC3W@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1976669_3	926549.KI421517_gene497	1.921e-122	400.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH2_k127_1976669_2	1392490.JHZX01000001_gene3514	7.108e-125	408.0	COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1HYEP@117743|Flavobacteriia	976|Bacteroidetes	G	Inward rectifier potassium channel	irk	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
DTH2_k127_1976669_6	1408433.JHXV01000007_gene2810	4.833e-64	224.0	COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1HZ1Y@117743|Flavobacteriia,2PATB@246874|Cryomorphaceae	976|Bacteroidetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH2_k127_1976669_7	1349785.BAUG01000027_gene1664	1.277e-59	211.0	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
DTH2_k127_1976669_9	362418.IW19_18900	4.201e-42	168.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia,2NSEB@237|Flavobacterium	976|Bacteroidetes	D	Sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_1976669_4	714943.Mucpa_5176	3.647e-90	303.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IQQ6@117747|Sphingobacteriia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DTH2_k127_1976669_8	1237149.C900_02393	9.673e-44	168.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
DTH2_k127_2009819_2	153721.MYP_1810	3.829e-152	486.0	COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,47JAE@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DTH2_k127_2009819_1	926549.KI421517_gene738	7.338e-181	572.0	COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,47N2Y@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DTH2_k127_2009819_3	1121904.ARBP01000007_gene2943	4.751e-151	494.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2009819_0	1121889.AUDM01000010_gene595	0.0	1467.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1HXFG@117743|Flavobacteriia,2NV9I@237|Flavobacterium	976|Bacteroidetes	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
DTH2_k127_2009819_5	1341155.FSS13T_00100	4.377e-141	453.0	COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1HZY7@117743|Flavobacteriia,2NUSF@237|Flavobacterium	976|Bacteroidetes	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
DTH2_k127_2009819_6	391598.FBBAL38_09234	2.818e-131	423.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia	976|Bacteroidetes	E	asparaginase	-	-	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_2009819_7	1313421.JHBV01000029_gene1950	2.708e-40	172.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_2009819_4	391598.FBBAL38_08809	1.392e-143	487.0	COG1470@1|root,COG2133@1|root,COG2304@1|root,COG2706@1|root,COG3209@1|root,COG3291@1|root,COG3420@1|root,COG4733@1|root,COG5279@1|root,COG1470@2|Bacteria,COG2133@2|Bacteria,COG2304@2|Bacteria,COG2706@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,COG5279@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia	976|Bacteroidetes	DZ	TIGRFAM Bacterial surface protein 26-residue repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,DUF285,TIG,TSP_3
DTH2_k127_2010599_8	762983.HMPREF9444_00683	3.322e-19	87.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,1RSN2@1236|Gammaproteobacteria,1Y3NP@135624|Aeromonadales	135624|Aeromonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
DTH2_k127_2010599_10	1392490.JHZX01000001_gene3470	1.256e-15	78.0	2E50X@1|root,32ZUB@2|Bacteria,4NW9R@976|Bacteroidetes,1I57F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2010599_4	926562.Oweho_0793	1.065e-80	279.0	COG0500@1|root,COG2226@2|Bacteria,4NN70@976|Bacteroidetes,1I1TK@117743|Flavobacteriia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
DTH2_k127_2010599_0	926562.Oweho_0955	0.0	1059.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1HYUM@117743|Flavobacteriia,2PA86@246874|Cryomorphaceae	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_2010599_3	745718.JADT01000012_gene862	7.041e-116	378.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1HXU4@117743|Flavobacteriia	976|Bacteroidetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS
DTH2_k127_2010599_2	755732.Fluta_3931	1.51e-182	579.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia,2PAA3@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_2010599_9	1356852.N008_14915	1.716e-18	91.0	COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47QE9@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_2010599_5	926562.Oweho_1037	9.917e-36	141.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_2010599_6	926562.Oweho_1037	5.338e-35	139.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_2010599_7	1121957.ATVL01000011_gene3865	3e-22	102.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,47R1B@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_2010599_1	1121889.AUDM01000014_gene1997	2.102e-287	894.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1HXRE@117743|Flavobacteriia,2NSQF@237|Flavobacterium	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DTH2_k127_2041993_0	926562.Oweho_1011	9.293e-120	398.0	COG0457@1|root,COG3303@1|root,COG0457@2|Bacteria,COG3303@2|Bacteria,4NDTY@976|Bacteroidetes,1HXS9@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_2,TPR_8
DTH2_k127_2041993_1	1168289.AJKI01000022_gene1896	1.673e-96	327.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,2FMVX@200643|Bacteroidia,3XJQ3@558415|Marinilabiliaceae	976|Bacteroidetes	S	YceG-like family	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
DTH2_k127_2041993_2	1227739.Hsw_3426	1.152e-94	339.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_2054043_0	468059.AUHA01000003_gene1570	1.916e-169	542.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH2_k127_2054043_5	1122225.AULQ01000004_gene1966	4.087e-41	154.0	2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
DTH2_k127_2054043_4	641526.ADIWIN_1446	2.635e-62	228.0	COG0845@1|root,COG0845@2|Bacteria,4NITE@976|Bacteroidetes,1HZI0@117743|Flavobacteriia	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
DTH2_k127_2054043_3	1239962.C943_01435	2.574e-90	312.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47MB4@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_2054043_2	1121896.JMLU01000007_gene204	6.264e-93	310.0	COG1136@1|root,COG1136@2|Bacteria,4NFCG@976|Bacteroidetes,1HZKS@117743|Flavobacteriia,2NUBC@237|Flavobacterium	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH2_k127_2054043_1	1519464.HY22_08815	2.925e-128	426.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
DTH2_k127_2113687_1	1121904.ARBP01000016_gene5289	6.182e-102	347.0	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia	976|Bacteroidetes	O	PFAM Cytochrome c assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
DTH2_k127_2113687_6	714943.Mucpa_5330	9.481e-50	187.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1IRXA@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
DTH2_k127_2113687_3	1286632.P278_08410	3.364e-62	220.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
DTH2_k127_2113687_5	485918.Cpin_1958	1.098e-56	210.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1IYC2@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH2_k127_2113687_4	1408473.JHXO01000004_gene269	2.145e-61	218.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DTH2_k127_2113687_0	762903.Pedsa_0255	1.084e-124	404.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1IQ5V@117747|Sphingobacteriia	976|Bacteroidetes	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DTH2_k127_2113687_2	755732.Fluta_3573	4.458e-67	233.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1HXJD@117743|Flavobacteriia,2PAB0@246874|Cryomorphaceae	976|Bacteroidetes	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DTH2_k127_2114785_2	1121373.KB903662_gene115	2.974e-47	174.0	COG2318@1|root,COG2318@2|Bacteria,4NREM@976|Bacteroidetes,47VNE@768503|Cytophagia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DTH2_k127_2114785_0	1250232.JQNJ01000001_gene2544	0.0	1054.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DTH2_k127_2114785_1	1392490.JHZX01000001_gene835	1.536e-148	477.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia	976|Bacteroidetes	M	glucose-1-phosphate thymidylyltransferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
DTH2_k127_2153624_0	1121904.ARBP01000005_gene4576	4.712e-45	180.0	COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4P2C8@976|Bacteroidetes,47UN6@768503|Cytophagia	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_12
DTH2_k127_2153624_3	869213.JCM21142_3965	1.388e-13	76.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2153624_1	1122176.KB903551_gene4214	1.781e-37	149.0	2AZZY@1|root,31SA0@2|Bacteria,4NRJ3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2153624_2	269798.CHU_3266	3.354e-18	86.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,47UJ0@768503|Cytophagia	976|Bacteroidetes	L	Exodeoxyribonuclease V, gamma subunit	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DTH2_k127_2206682_1	926549.KI421517_gene1852	5.894e-131	425.0	COG1208@1|root,COG1208@2|Bacteria,4NE97@976|Bacteroidetes,47ND5@768503|Cytophagia	976|Bacteroidetes	JM	Nucleotidyl transferase	rffH	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DTH2_k127_2206682_3	945713.IALB_0328	7.77e-52	185.0	2AFHA@1|root,315HT@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_2206682_2	694427.Palpr_2021	2.22e-68	234.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,2FR7A@200643|Bacteroidia,22XVH@171551|Porphyromonadaceae	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
DTH2_k127_2206682_0	243233.MCA1772	1.082e-159	517.0	COG2244@1|root,COG2244@2|Bacteria,1R512@1224|Proteobacteria,1RZ0F@1236|Gammaproteobacteria,1XE8D@135618|Methylococcales	135618|Methylococcales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_2206682_4	313598.MED152_09160	4.432e-44	162.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,3VWJ9@52959|Polaribacter	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH2_k127_2208220_3	1123248.KB893385_gene4781	4.665e-121	394.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1IYHV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH2_k127_2208220_0	485918.Cpin_1031	1.74e-165	526.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,1IZ5W@117747|Sphingobacteriia	976|Bacteroidetes	C	COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_2208220_1	1313421.JHBV01000039_gene2760	4.312e-143	481.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_2208220_2	153721.MYP_2040	7.84e-125	403.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47XX0@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_2208220_4	929556.Solca_0221	2.828e-85	296.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_2288025_4	485917.Phep_3451	1.844e-92	310.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DTH2_k127_2288025_1	468059.AUHA01000008_gene2751	7.365e-156	509.0	COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,4NHH4@976|Bacteroidetes,1IQUA@117747|Sphingobacteriia	976|Bacteroidetes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC
DTH2_k127_2288025_0	468059.AUHA01000008_gene2750	8.047e-166	525.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
DTH2_k127_2288025_2	1168034.FH5T_06740	4.18e-132	432.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,2FPWJ@200643|Bacteroidia	976|Bacteroidetes	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_2288025_5	483216.BACEGG_03456	7.14e-86	287.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,4AKX2@815|Bacteroidaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DTH2_k127_2288025_3	1313301.AUGC01000013_gene1270	2.374e-114	387.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_2323618_1	929556.Solca_1740	6.656e-56	201.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1ISYC@117747|Sphingobacteriia	976|Bacteroidetes	K	acr, cog1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
DTH2_k127_2323618_0	714943.Mucpa_4231	2.807e-214	672.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1IPUW@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DTH2_k127_2327465_0	714943.Mucpa_2062	1.099e-164	533.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPEH@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_2327465_2	1356852.N008_10580	2.554e-66	241.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47S2Z@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_2327465_1	204536.SULAZ_0349	1.718e-84	288.0	COG0367@1|root,COG0367@2|Bacteria,2G4Q5@200783|Aquificae	200783|Aquificae	F	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_233209_0	1168034.FH5T_08385	2.08e-171	565.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_233209_1	1356852.N008_11255	9.574e-83	283.0	COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,47KJ1@768503|Cytophagia	976|Bacteroidetes	CE	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
DTH2_k127_2379024_3	1121373.KB903623_gene2332	1.456e-32	137.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4P298@976|Bacteroidetes,47TIX@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_2379024_1	1121957.ATVL01000006_gene3010	3.266e-87	300.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DTH2_k127_2379024_2	1237149.C900_01567	4.212e-82	298.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
DTH2_k127_2379024_0	1227739.Hsw_3426	8.665e-161	521.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_2469569_3	1123248.KB893314_gene3375	2.484e-35	134.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1INUJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_2469569_1	743722.Sph21_3980	1.616e-61	215.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,1IRJ7@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DTH2_k127_2469569_2	1453500.AT05_10425	3.776e-61	213.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,1I18N@117743|Flavobacteriia	976|Bacteroidetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DTH2_k127_2469569_0	1313421.JHBV01000039_gene2760	2.493e-125	426.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_2485662_0	926556.Echvi_1154	4.962e-87	293.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,47MHF@768503|Cytophagia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
DTH2_k127_2485662_2	468059.AUHA01000005_gene2471	8.979e-28	125.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,1IQNW@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_2485662_3	760192.Halhy_3864	1.762e-25	116.0	COG1361@1|root,COG3209@1|root,COG4886@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG4886@2|Bacteria,4PKBQ@976|Bacteroidetes	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_2485662_1	1174528.JH992898_gene804	4.394e-28	123.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
DTH2_k127_2528633_2	929556.Solca_0931	3.223e-43	168.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
DTH2_k127_2528633_1	269798.CHU_1793	1.335e-136	447.0	COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,47KKP@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH2_k127_2528633_0	468059.AUHA01000002_gene108	1.894e-174	565.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DTH2_k127_2528633_3	331678.Cphamn1_2031	3.547e-35	137.0	COG0612@1|root,COG0612@2|Bacteria,1FDGF@1090|Chlorobi	1090|Chlorobi	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_2543383_1	643867.Ftrac_0021	2.772e-101	336.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
DTH2_k127_2543383_0	1406840.Q763_08685	1.102e-128	414.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia,2NTEM@237|Flavobacterium	976|Bacteroidetes	Q	Homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
DTH2_k127_2582583_3	1379698.RBG1_1C00001G1816	5.807e-11	70.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
DTH2_k127_2582583_2	926549.KI421517_gene2227	4.817e-140	463.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_2582583_0	929556.Solca_0363	2.474e-195	614.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1IPBI@117747|Sphingobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
DTH2_k127_2582583_1	1121373.KB903625_gene3160	5.492e-156	527.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_2693922_3	1392490.JHZX01000001_gene2181	1.384e-75	268.0	COG2234@1|root,COG3291@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.8,3.4.11.10	ko:K01181,ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,DUF285,F5_F8_type_C,LRR_5,Peptidase_M28
DTH2_k127_2693922_0	1288963.ADIS_0011	1.962e-199	627.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
DTH2_k127_2693922_2	1313421.JHBV01000015_gene5746	5.271e-96	329.0	COG1215@1|root,COG1215@2|Bacteria,4NN4F@976|Bacteroidetes,1J064@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_2693922_1	1168034.FH5T_01205	7.754e-112	374.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,2FQT6@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DTH2_k127_2693922_4	762903.Pedsa_0361	1.936e-26	110.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,1INY8@117747|Sphingobacteriia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_2702965_2	755732.Fluta_2281	1.355e-14	83.0	2ABIA@1|root,310ZH@2|Bacteria,4PFMS@976|Bacteroidetes,1ICAQ@117743|Flavobacteriia,2PB8S@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2702965_3	1122978.AUFP01000002_gene2027	1.932e-14	78.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes	976|Bacteroidetes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
DTH2_k127_2702965_1	1185876.BN8_01509	1.059e-38	146.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DTH2_k127_2702965_0	929556.Solca_4126	1.557e-119	387.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH2_k127_2740619_3	1123276.KB893254_gene3499	6.674e-08	57.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47KCX@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_2740619_0	1454007.JAUG01000124_gene1073	3.551e-129	430.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH2_k127_2740619_1	925409.KI911562_gene2950	4.564e-87	295.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1IP8Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
DTH2_k127_2740619_2	1406840.Q763_14685	4.882e-35	141.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1I18T@117743|Flavobacteriia,2NSUZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2740619_4	1517682.HW49_06840	5.661e-06	52.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,2FP81@200643|Bacteroidia,22WNK@171551|Porphyromonadaceae	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DTH2_k127_2969412_5	755732.Fluta_2847	4.347e-112	367.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia,2PA74@246874|Cryomorphaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_2969412_6	1168034.FH5T_11305	4.253e-100	337.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,2FN2X@200643|Bacteroidia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
DTH2_k127_2969412_4	153721.MYP_4777	4.639e-127	424.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,47MYA@768503|Cytophagia	976|Bacteroidetes	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
DTH2_k127_2969412_1	762903.Pedsa_2906	2.481e-304	941.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1IQXV@117747|Sphingobacteriia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_2969412_7	760192.Halhy_4009	3.314e-92	310.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
DTH2_k127_2969412_8	1223410.KN050846_gene2611	1.476e-78	270.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,1HX93@117743|Flavobacteriia	976|Bacteroidetes	S	zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
DTH2_k127_2969412_0	886379.AEWI01000023_gene8	8.839e-317	985.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,3XJ41@558415|Marinilabiliaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
DTH2_k127_2969412_10	153721.MYP_3679	0.0003048	51.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_2969412_2	1358423.N180_12720	6.176e-150	479.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH2_k127_2969412_9	755732.Fluta_3294	2.093e-62	226.0	2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
DTH2_k127_2969412_3	755732.Fluta_3295	5.286e-137	448.0	COG4206@1|root,COG4206@2|Bacteria,4PM6D@976|Bacteroidetes,1IN1U@117743|Flavobacteriia	976|Bacteroidetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_3004267_3	1434325.AZQN01000011_gene3738	2.718e-112	370.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
DTH2_k127_3004267_11	926551.KB900715_gene2156	1.064e-25	114.0	COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,1HXIW@117743|Flavobacteriia,1ER40@1016|Capnocytophaga	976|Bacteroidetes	CO	Redoxin family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
DTH2_k127_3004267_10	1122605.KB893644_gene1518	2.48e-31	127.0	COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,1ITMI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH2_k127_3004267_12	1168034.FH5T_09290	5.745e-20	99.0	COG3637@1|root,COG3637@2|Bacteria,4NYY3@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
DTH2_k127_3004267_4	760192.Halhy_3207	8.404e-95	336.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,1ITJC@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
DTH2_k127_3004267_5	1408433.JHXV01000015_gene1712	1.532e-93	314.0	COG3279@1|root,COG3279@2|Bacteria,4NKXC@976|Bacteroidetes,1I0BK@117743|Flavobacteriia,2PAUQ@246874|Cryomorphaceae	976|Bacteroidetes	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH2_k127_3004267_7	1220534.B655_2107	1.362e-83	302.0	COG0642@1|root,arCOG02348@1|root,arCOG02348@2157|Archaea,arCOG06192@2157|Archaea	2157|Archaea	T	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH2_k127_3004267_2	926562.Oweho_2308	8.929e-132	438.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBM8@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_3004267_1	929556.Solca_3853	3.054e-163	518.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
DTH2_k127_3004267_6	929556.Solca_1416	5.61e-84	284.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1INTC@117747|Sphingobacteriia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
DTH2_k127_3004267_0	714943.Mucpa_4254	0.0	1045.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
DTH2_k127_3004267_9	1122176.KB903540_gene20	5.648e-39	166.0	COG0526@1|root,COG1404@1|root,COG0526@2|Bacteria,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	AhpC-TSA,B_lectin,Omp28
DTH2_k127_3004267_8	1408433.JHXV01000008_gene153	1.449e-51	205.0	COG3291@1|root,COG4188@1|root,COG3291@2|Bacteria,COG4188@2|Bacteria,4NKC2@976|Bacteroidetes,1HZ4A@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
DTH2_k127_3004267_13	755732.Fluta_3718	0.0001846	44.0	2BFVS@1|root,32WJ0@2|Bacteria,4PGMC@976|Bacteroidetes,1IFB5@117743|Flavobacteriia,2PC3U@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3018282_3	1121895.Q765_10355	1.314e-34	143.0	2C80G@1|root,2Z7ZW@2|Bacteria,4NNAX@976|Bacteroidetes,1I0PF@117743|Flavobacteriia,2NSAP@237|Flavobacterium	976|Bacteroidetes	S	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
DTH2_k127_3018282_0	1341155.FSS13T_00710	6.704e-155	511.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,1HYIY@117743|Flavobacteriia,2NTEA@237|Flavobacterium	976|Bacteroidetes	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
DTH2_k127_3018282_2	929556.Solca_3455	8.633e-63	222.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1IRU0@117747|Sphingobacteriia	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DTH2_k127_3018282_1	643867.Ftrac_1814	1.552e-130	422.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_3063612_1	929713.NIASO_10755	3.901e-203	635.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH2_k127_3063612_7	1443665.JACA01000013_gene4157	1.623e-63	222.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2YJI5@290174|Aquimarina	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DTH2_k127_3063612_0	929562.Emtol_2892	6.87e-322	995.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,47K1X@768503|Cytophagia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_3063612_6	700598.Niako_4281	1.174e-70	259.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria,4NN21@976|Bacteroidetes	976|Bacteroidetes	UW	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH2_k127_3063612_12	1120966.AUBU01000002_gene1966	1.212e-21	101.0	28NMY@1|root,2ZBNE@2|Bacteria,4NN50@976|Bacteroidetes,47PGY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3063612_9	929562.Emtol_4156	1.338e-47	175.0	COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia	976|Bacteroidetes	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_3063612_2	1408813.AYMG01000033_gene5249	1.069e-166	529.0	COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1IQAD@117747|Sphingobacteriia	976|Bacteroidetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
DTH2_k127_3063612_4	1506583.JQJY01000010_gene1187	6.17e-82	306.0	COG2911@1|root,COG3209@1|root,COG4677@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG4677@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
DTH2_k127_3063612_15	485918.Cpin_1738	4.553e-15	90.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1IXWG@117747|Sphingobacteriia	976|Bacteroidetes	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
DTH2_k127_3063612_5	700598.Niako_0505	2.092e-80	301.0	COG4447@1|root,COG5492@1|root,COG4447@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,PIG-L,VCBS,WxL
DTH2_k127_3063612_14	521011.Mpal_1796	1.111e-15	92.0	COG0614@1|root,COG3291@1|root,arCOG02510@2157|Archaea,arCOG03611@2157|Archaea	2157|Archaea	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CBM_6,DUF3344,Lipase_GDSL_2,NHL,NosD,PKD,Peptidase_C1,Peptidase_S8
DTH2_k127_3063612_8	1123248.KB893317_gene4364	7.657e-48	198.0	COG1404@1|root,COG3291@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4PM1B@976|Bacteroidetes,1IXBK@117747|Sphingobacteriia	976|Bacteroidetes	G	SPTR Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
DTH2_k127_3063612_3	700598.Niako_0505	1.334e-98	353.0	COG4447@1|root,COG5492@1|root,COG4447@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,PIG-L,VCBS,WxL
DTH2_k127_3063612_11	755732.Fluta_2399	3.274e-38	166.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_3063612_10	1121904.ARBP01000007_gene2943	7.918e-43	175.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3063612_13	867900.Celly_3113	1.69e-18	88.0	COG4625@1|root,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,1I8TP@117743|Flavobacteriia,1F9W2@104264|Cellulophaga	976|Bacteroidetes	S	Ricin-type beta-trefoil lectin domain-like	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
DTH2_k127_309938_7	927658.AJUM01000037_gene2090	2.979e-20	94.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,2FN1M@200643|Bacteroidia,3XIN2@558415|Marinilabiliaceae	976|Bacteroidetes	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
DTH2_k127_309938_9	1250005.PHEL85_0653	6.154e-16	88.0	2E6TM@1|root,331DG@2|Bacteria,4NYW8@976|Bacteroidetes,1I8QW@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
DTH2_k127_309938_2	929562.Emtol_0904	3.809e-73	252.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,47PEP@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
DTH2_k127_309938_3	929703.KE386491_gene175	7.958e-58	210.0	COG3025@1|root,COG3025@2|Bacteria,4NM6K@976|Bacteroidetes,47PAH@768503|Cytophagia	976|Bacteroidetes	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH2_k127_309938_10	641143.HMPREF9331_00234	3.407e-07	59.0	COG3209@1|root,COG3209@2|Bacteria,4PECV@976|Bacteroidetes,1IEW5@117743|Flavobacteriia,1ERDX@1016|Capnocytophaga	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_309938_8	1121899.Q764_05285	6.309e-18	88.0	2A9DB@1|root,30YIH@2|Bacteria,4PCCI@976|Bacteroidetes,1ICZ6@117743|Flavobacteriia,2NWA7@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_309938_1	247490.KSU1_C0449	6.034e-107	366.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
DTH2_k127_309938_0	929556.Solca_4375	7.952e-143	457.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,1IQJG@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
DTH2_k127_309938_6	1267211.KI669560_gene1434	3.834e-27	120.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_309938_5	485917.Phep_0515	2.549e-51	186.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,1ISTX@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM OsmC-like protein	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
DTH2_k127_309938_4	886379.AEWI01000002_gene491	6.236e-53	191.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,2FM57@200643|Bacteroidia,3XKG1@558415|Marinilabiliaceae	976|Bacteroidetes	L	Uracil DNA glycosylase superfamily	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DTH2_k127_3137332_3	316067.Geob_3768	0.0002177	44.0	COG4313@1|root,COG4313@2|Bacteria,1NW7I@1224|Proteobacteria,42ZUG@68525|delta/epsilon subdivisions,2WVAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DTH2_k127_3137332_1	1219049.SP5_032_00130	2.098e-15	86.0	COG3637@1|root,COG3637@2|Bacteria,1PW82@1224|Proteobacteria,2U8GW@28211|Alphaproteobacteria,2K6DC@204457|Sphingomonadales	204457|Sphingomonadales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3137332_2	1453505.JASY01000001_gene3732	1.668e-10	66.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
DTH2_k127_3137332_0	1121904.ARBP01000010_gene2257	1.29e-71	251.0	COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia	976|Bacteroidetes	G	N-acetylglucosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DTH2_k127_3192289_0	1124780.ANNU01000048_gene2121	6.452e-167	531.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
DTH2_k127_3192289_3	929556.Solca_3896	7.493e-51	183.0	COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia	976|Bacteroidetes	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
DTH2_k127_3192289_2	153721.MYP_3617	1.408e-52	190.0	COG4430@1|root,COG4430@2|Bacteria,4NR0U@976|Bacteroidetes,47PZ9@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
DTH2_k127_3192289_1	927658.AJUM01000034_gene294	5.141e-66	235.0	2DBTB@1|root,2ZAWY@2|Bacteria,4NIYP@976|Bacteroidetes,2G3EG@200643|Bacteroidia,3XJBQ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
DTH2_k127_3220374_1	1408473.JHXO01000006_gene1402	8.646e-96	330.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein, OMP85 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_3220374_3	760192.Halhy_5079	1.124e-15	82.0	COG2010@1|root,COG2010@2|Bacteria,4PEWN@976|Bacteroidetes,1IXW6@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
DTH2_k127_3220374_0	1408473.JHXO01000005_gene1646	3.861e-153	489.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FWQX@200643|Bacteroidia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_3220374_2	926562.Oweho_0145	1.405e-71	251.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1HXTE@117743|Flavobacteriia,2PA5V@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
DTH2_k127_3225499_3	153721.MYP_218	1.691e-28	120.0	COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,47XX5@768503|Cytophagia	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,UPF0227
DTH2_k127_3225499_2	926549.KI421517_gene3046	4.181e-93	310.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH2_k127_3225499_4	588596.U9UQL0	4.281e-07	61.0	COG0790@1|root,KOG1550@2759|Eukaryota	588596.U9UQL0|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3225499_1	1121957.ATVL01000006_gene2511	8.824e-110	359.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH2_k127_3225499_0	926562.Oweho_3391	1.691e-318	988.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1HXMR@117743|Flavobacteriia,2PAAM@246874|Cryomorphaceae	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH2_k127_324047_5	32049.SYNPCC7002_A1987	6.367e-23	102.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1GZQH@1129|Synechococcus	1117|Cyanobacteria	M	Peptidyl-prolyl cis-trans	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DTH2_k127_324047_1	1094466.KQS_09615	3.808e-118	390.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,2NTC4@237|Flavobacterium	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiB	-	5.2.1.8	ko:K01802,ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Pro_isomerase
DTH2_k127_324047_0	926562.Oweho_1165	3.29e-134	431.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1HXEE@117743|Flavobacteriia,2PAFE@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
DTH2_k127_324047_2	1249975.JQLP01000003_gene115	2.755e-93	312.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,1HXBY@117743|Flavobacteriia,2P5UQ@244698|Gillisia	976|Bacteroidetes	J	RNA pseudouridylate synthase	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
DTH2_k127_324047_4	1121904.ARBP01000009_gene4385	3.208e-28	127.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_324047_3	1189612.A33Q_0813	1.16e-29	122.0	COG0216@1|root,COG0216@2|Bacteria,4PPXH@976|Bacteroidetes,47YSM@768503|Cytophagia	976|Bacteroidetes	J	RF-1 domain	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
DTH2_k127_3287896_2	1500897.JQNA01000002_gene851	3.039e-21	98.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,1K4AM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
DTH2_k127_3287896_1	118173.KB235914_gene4070	5.932e-82	280.0	COG0730@1|root,COG0730@2|Bacteria,1G8EH@1117|Cyanobacteria,1HCXE@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_3287896_0	886379.AEWI01000209_gene2468	3.141e-152	488.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,2FM7Y@200643|Bacteroidia,3XJRR@558415|Marinilabiliaceae	976|Bacteroidetes	L	helicase superfamily c-terminal domain	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
DTH2_k127_3340535_4	984262.SGRA_0169	1.287e-19	91.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1ITIS@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_3340535_3	1168034.FH5T_16670	1.546e-78	273.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,2FMU4@200643|Bacteroidia	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DTH2_k127_3340535_0	1121887.AUDK01000031_gene1044	1.991e-124	405.0	COG0111@1|root,COG0111@2|Bacteria,4NDVN@976|Bacteroidetes,1HWXS@117743|Flavobacteriia,2NTEG@237|Flavobacterium	976|Bacteroidetes	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH2_k127_3340535_2	1519464.HY22_07155	9.865e-89	298.0	COG0217@1|root,COG0217@2|Bacteria,1FDKV@1090|Chlorobi	1090|Chlorobi	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DTH2_k127_3340535_1	1453500.AT05_00910	1.665e-91	304.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
DTH2_k127_3369473_4	926562.Oweho_1021	3.213e-54	199.0	COG0589@1|root,COG0589@2|Bacteria,4NGG8@976|Bacteroidetes,1HYY4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_3369473_0	1123057.P872_21955	4.066e-140	456.0	COG0475@1|root,COG0475@2|Bacteria,4NFPE@976|Bacteroidetes,47NZK@768503|Cytophagia	976|Bacteroidetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DTH2_k127_3369473_5	700598.Niako_0133	1.661e-23	104.0	2E373@1|root,32ZYW@2|Bacteria,4PQ2K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3369473_3	1202532.FF52_14531	1.127e-86	289.0	COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,1HYKM@117743|Flavobacteriia,2NTPY@237|Flavobacterium	976|Bacteroidetes	FJ	tRNA hydroxylase	miaE	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
DTH2_k127_3369473_1	946077.W5A_00895	4.526e-134	432.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,1HX48@117743|Flavobacteriia	976|Bacteroidetes	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_3369473_2	714943.Mucpa_5230	2.518e-87	291.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1IPU5@117747|Sphingobacteriia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_3423626_12	755732.Fluta_3196	0.0004605	44.0	2EDGF@1|root,337CN@2|Bacteria,4NXB6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3423626_6	755732.Fluta_3197	1.536e-44	172.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia,2PBZJ@246874|Cryomorphaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_3423626_8	755732.Fluta_3198	2.02e-28	119.0	COG2259@1|root,COG2259@2|Bacteria,4NVWM@976|Bacteroidetes,1I5GY@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
DTH2_k127_3423626_2	755732.Fluta_3200	9.339e-149	478.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1HY0Y@117743|Flavobacteriia,2PBK1@246874|Cryomorphaceae	976|Bacteroidetes	T	Bacterial regulatory proteins, crp family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
DTH2_k127_3423626_3	929562.Emtol_0376	7.661e-130	426.0	COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DTH2_k127_3423626_10	1249975.JQLP01000005_gene2505	7.882e-13	76.0	2EK5W@1|root,33DWA@2|Bacteria,4NY2G@976|Bacteroidetes,1I6AV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3423626_0	1121896.JMLU01000028_gene2815	8.626e-212	711.0	COG1361@1|root,COG1361@2|Bacteria,4PPKX@976|Bacteroidetes,1IKQH@117743|Flavobacteriia,2P0TU@237|Flavobacterium	976|Bacteroidetes	M	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3423626_1	1392488.JHZY01000004_gene2539	1.271e-150	527.0	COG2911@1|root,COG3209@1|root,COG5184@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_3423626_5	641526.ADIWIN_2142	9.335e-52	194.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_3423626_11	313606.M23134_02495	6.699e-08	59.0	2CEJK@1|root,32UDJ@2|Bacteria,4NU95@976|Bacteroidetes,47SHJ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TerB
DTH2_k127_3423626_4	1121904.ARBP01000009_gene4289	3.094e-101	339.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,47MW1@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH2_k127_3423626_9	641524.ADICYQ_5155	4.852e-27	122.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,47RX5@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
DTH2_k127_3423626_7	1461577.CCMH01000016_gene343	6.113e-33	136.0	COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_3433889_4	1150600.ADIARSV_3033	1.483e-37	143.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,1ISPN@117747|Sphingobacteriia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH2_k127_3433889_0	1270196.JCKI01000002_gene493	5.187e-164	524.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH2_k127_3433889_3	1121904.ARBP01000007_gene2943	1.009e-49	196.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3433889_1	1313421.JHBV01000016_gene5527	3.955e-141	473.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1IWYM@117747|Sphingobacteriia	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
DTH2_k127_3433889_2	459349.CLOAM1219	3.831e-136	461.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_3433889_5	755732.Fluta_0605	2.823e-28	129.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2PAUX@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
DTH2_k127_3433889_6	880073.Calab_2100	4.977e-20	94.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
DTH2_k127_3460925_2	926562.Oweho_3031	4.501e-67	239.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2PBRD@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Peptidase family M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_3460925_1	929703.KE386491_gene3346	2.123e-81	278.0	COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia	976|Bacteroidetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DTH2_k127_3460925_3	945713.IALB_1488	1.657e-55	208.0	COG3291@1|root,COG4409@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4409@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	wcoB	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix,PKD,Reprolysin_4
DTH2_k127_3460925_0	468059.AUHA01000003_gene1886	6.1e-167	532.0	COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,1INXN@117747|Sphingobacteriia	976|Bacteroidetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_3464709_5	886379.AEWI01000146_gene3235	4.303e-32	135.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_3464709_4	1410666.JHXG01000017_gene1551	1.402e-67	237.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,2FNE2@200643|Bacteroidia	976|Bacteroidetes	J	RNA methyltransferase TrmH	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_3464709_2	1408473.JHXO01000006_gene1183	1e-93	319.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,2FP24@200643|Bacteroidia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_3464709_3	1408473.JHXO01000006_gene1182	1.249e-71	249.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,2FM71@200643|Bacteroidia	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
DTH2_k127_3464709_0	1237149.C900_00764	3.408e-173	551.0	COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
DTH2_k127_3464709_1	269798.CHU_1558	3.655e-100	363.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4P298@976|Bacteroidetes,47TIX@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_3498536_3	1123276.KB893254_gene3499	6.14e-170	542.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47KCX@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_3498536_0	929556.Solca_2012	3.624e-284	886.0	COG0043@1|root,COG0043@2|Bacteria,4NHHV@976|Bacteroidetes,1IR14@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH2_k127_3498536_2	1267211.KI669560_gene1380	2.251e-201	635.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1IQX9@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DTH2_k127_3498536_1	1124780.ANNU01000035_gene214	5.098e-210	659.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DTH2_k127_3507924_12	1313301.AUGC01000013_gene1270	2.61e-27	117.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_3507924_10	153721.MYP_3682	1.328e-60	215.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.187,2.1.1.197	ko:K00563,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R07233,R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
DTH2_k127_3507924_7	1168034.FH5T_06745	1.356e-118	397.0	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,2G3BA@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_3507924_6	1313421.JHBV01000030_gene2256	3.019e-130	430.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia	976|Bacteroidetes	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DTH2_k127_3507924_8	1237149.C900_01615	1.514e-97	326.0	COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,47JF0@768503|Cytophagia	976|Bacteroidetes	S	of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
DTH2_k127_3507924_2	1313421.JHBV01000024_gene5040	6.362e-188	595.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
DTH2_k127_3507924_1	468059.AUHA01000005_gene2517	3.542e-217	683.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1IPBW@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DTH2_k127_3507924_3	1122176.KB903558_gene4166	5.483e-146	482.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Kelch_1,Malectin,PKD,Peptidase_M6,Peptidase_S8
DTH2_k127_3507924_5	1185876.BN8_04500	8.049e-131	426.0	COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia	976|Bacteroidetes	EH	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH2_k127_3507924_11	313606.M23134_03755	1.81e-28	119.0	COG0662@1|root,COG0662@2|Bacteria,4NVCS@976|Bacteroidetes	976|Bacteroidetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MannoseP_isomer
DTH2_k127_3507924_0	468059.AUHA01000002_gene1176	3.305e-316	978.0	COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,1INUN@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_3507924_9	945713.IALB_0215	1.343e-77	263.0	COG2818@1|root,COG2818@2|Bacteria	2|Bacteria	L	DNA-3-methyladenine glycosylase activity	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DTH2_k127_3507924_13	313603.FB2170_17341	3.242e-08	60.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia,2PHTD@252356|Maribacter	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH2_k127_3507924_4	762903.Pedsa_2992	3.39e-135	439.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DTH2_k127_3513262_3	709991.Odosp_0784	0.0006993	48.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NDV9@976|Bacteroidetes,2FNGB@200643|Bacteroidia,2321U@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
DTH2_k127_3513262_0	1121887.AUDK01000008_gene1203	2.905e-89	320.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1ICYX@117743|Flavobacteriia,2NW87@237|Flavobacterium	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_3513262_2	762903.Pedsa_3676	2.459e-41	161.0	COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia	976|Bacteroidetes	F	Pyrimidine operon attenuation protein uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DTH2_k127_3513262_1	760192.Halhy_0181	2.24e-52	195.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IPEH@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_3539189_4	1121904.ARBP01000007_gene2910	7.541e-30	125.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes	976|Bacteroidetes	M	tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
DTH2_k127_3539189_1	714943.Mucpa_6112	3.775e-130	437.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1IR9Z@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
DTH2_k127_3539189_3	1408473.JHXO01000004_gene60	1.213e-53	198.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH2_k127_3539189_2	1034807.FBFL15_1513	4.925e-68	234.0	COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1I19W@117743|Flavobacteriia,2NT06@237|Flavobacterium	976|Bacteroidetes	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
DTH2_k127_3539189_0	504832.OCAR_4382	3.059e-155	505.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,3JQY5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DTH2_k127_3539189_6	929556.Solca_0934	3.603e-09	64.0	2ADZU@1|root,313SD@2|Bacteria,4PK7E@976|Bacteroidetes,1IUKW@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
DTH2_k127_3539189_5	1121957.ATVL01000009_gene1012	1.504e-12	68.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,47JEX@768503|Cytophagia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_3565422_4	929556.Solca_2746	6.655e-42	158.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IS84@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
DTH2_k127_3565422_3	1239962.C943_01092	6.767e-83	285.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,47NUX@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_3565422_1	525373.HMPREF0766_11560	1.003e-123	403.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,1IPDS@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
DTH2_k127_3565422_2	760192.Halhy_4831	3.114e-112	384.0	COG2706@1|root,COG3210@1|root,COG3291@1|root,COG5492@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NN8J@976|Bacteroidetes,1IUSR@117747|Sphingobacteriia	976|Bacteroidetes	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_3565422_0	1358423.N180_20205	5.327e-127	412.0	COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,1IPMT@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_3565422_5	1121943.KB899999_gene1352	1.827e-20	91.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,1RQHJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
DTH2_k127_3576976_4	1408433.JHXV01000032_gene1131	2.472e-31	126.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1HWTE@117743|Flavobacteriia,2PADU@246874|Cryomorphaceae	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DTH2_k127_3576976_0	1408433.JHXV01000032_gene1130	2.734e-174	556.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia,2PA5T@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DTH2_k127_3576976_3	485917.Phep_3324	2.876e-55	203.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IX3I@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
DTH2_k127_3576976_1	929556.Solca_2737	2.173e-153	498.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_3576976_2	1121904.ARBP01000005_gene4500	1.021e-63	224.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DTH2_k127_3593246_1	313598.MED152_12699	2.08e-86	301.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,1HXZZ@117743|Flavobacteriia,3VW8Q@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_3593246_4	714943.Mucpa_5226	1.907e-38	144.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ITGS@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DTH2_k127_3593246_6	215803.DB30_8855	5.442e-08	63.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5011
DTH2_k127_3593246_0	385682.AFSL01000073_gene1395	2.343e-148	491.0	COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,2FNHQ@200643|Bacteroidia,3XKJM@558415|Marinilabiliaceae	976|Bacteroidetes	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_3593246_2	869213.JCM21142_83091	3.576e-81	279.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,47PDK@768503|Cytophagia	976|Bacteroidetes	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_3593246_5	65093.PCC7418_0806	8.82e-23	103.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3593246_3	755732.Fluta_0797	1.712e-59	213.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
DTH2_k127_3594290_1	1094466.KQS_03855	5.365e-46	168.0	COG4319@1|root,COG4319@2|Bacteria,4NS10@976|Bacteroidetes,1II83@117743|Flavobacteriia,2NWG5@237|Flavobacterium	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
DTH2_k127_3594290_2	1185876.BN8_05067	3.218e-20	94.0	COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,47RHB@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
DTH2_k127_3594290_3	1123277.KB893172_gene957	9.63e-07	57.0	2EH68@1|root,33AY4@2|Bacteria,4NYTD@976|Bacteroidetes,47T1H@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3594290_0	1122179.KB890417_gene3235	1.708e-108	361.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1IPKH@117747|Sphingobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
DTH2_k127_3672005_0	1250005.PHEL85_0753	1.12e-112	366.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia,3VV7I@52959|Polaribacter	976|Bacteroidetes	S	Thiazole biosynthesis protein ThiG	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
DTH2_k127_3672005_3	1408433.JHXV01000029_gene3118	1.636e-64	232.0	COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_3672005_1	1124780.ANNU01000002_gene1538	2.448e-85	289.0	COG1215@1|root,COG1215@2|Bacteria,4PM37@976|Bacteroidetes,47YI8@768503|Cytophagia	976|Bacteroidetes	M	glycosyl transferase	wbyL	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_3672005_2	1304874.JAFY01000007_gene1678	5.595e-85	295.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_3724221_5	983544.Lacal_0549	2.348e-80	271.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DTH2_k127_3724221_4	485918.Cpin_6977	1.149e-109	366.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DTH2_k127_3724221_2	1408473.JHXO01000001_gene2462	6.764e-170	551.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,2FP0X@200643|Bacteroidia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH2_k127_3724221_1	1408433.JHXV01000032_gene1124	5.115e-183	580.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia,2PAGT@246874|Cryomorphaceae	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
DTH2_k127_3724221_0	468059.AUHA01000004_gene2172	6.349e-200	634.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_3724221_3	869213.JCM21142_31289	2.3e-119	395.0	COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,47K6U@768503|Cytophagia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH2_k127_3777871_2	1408433.JHXV01000011_gene2093	4.981e-89	309.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
DTH2_k127_3777871_1	1168034.FH5T_09495	4.846e-108	353.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,2FN8E@200643|Bacteroidia	976|Bacteroidetes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DTH2_k127_3777871_0	743722.Sph21_2926	3.56e-121	394.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,1IP06@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DTH2_k127_3883010_2	1121889.AUDM01000002_gene448	2.037e-11	66.0	COG3210@1|root,COG4675@1|root,COG5295@1|root,COG3210@2|Bacteria,COG4675@2|Bacteria,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_3883010_0	153721.MYP_243	6.826e-95	340.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_3883010_1	755732.Fluta_1203	1.033e-69	251.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,1I7GW@117743|Flavobacteriia,2PAW4@246874|Cryomorphaceae	976|Bacteroidetes	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
DTH2_k127_3883811_1	869213.JCM21142_144	3.638e-106	349.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,47JE2@768503|Cytophagia	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DTH2_k127_3883811_2	1249975.JQLP01000005_gene1138	5.118e-66	229.0	COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia,2P6KK@244698|Gillisia	976|Bacteroidetes	J	SpoU rRNA Methylase family	spoU	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
DTH2_k127_3883811_0	869213.JCM21142_72668	3.338e-118	400.0	COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes	976|Bacteroidetes	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_3883811_3	1123277.KB893172_gene799	5.464e-36	141.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,47QG8@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
DTH2_k127_391517_4	1341155.FSS13T_01530	2.194e-124	409.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,1I1TA@117743|Flavobacteriia,2NTRJ@237|Flavobacterium	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_391517_14	1178825.ALIH01000002_gene895	1.678e-31	131.0	2F1YU@1|root,33UY6@2|Bacteria,4P2VN@976|Bacteroidetes,1I8MH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_391517_18	1191523.MROS_2048	2.486e-06	59.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
DTH2_k127_391517_6	153721.MYP_1941	7.166e-106	348.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47KCT@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH2_k127_391517_17	1123248.KB893328_gene917	5.404e-16	82.0	COG3245@1|root,COG3245@2|Bacteria,4NRNS@976|Bacteroidetes,1IZF9@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_391517_19	1313421.JHBV01000046_gene291	5.007e-05	50.0	2DGVM@1|root,2ZXFN@2|Bacteria,4P8FH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_391517_10	1296415.JACC01000006_gene1509	1.909e-61	233.0	COG2960@1|root,COG2960@2|Bacteria,4NI9S@976|Bacteroidetes,1ICN0@117743|Flavobacteriia,2YKN6@290174|Aquimarina	976|Bacteroidetes	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_391517_16	700598.Niako_5150	2.119e-27	128.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH2_k127_391517_1	936154.STP_1828	4.845e-152	503.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli	91061|Bacilli	I	Dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_2
DTH2_k127_391517_8	706587.Desti_1480	4.035e-76	263.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_391517_0	1187851.A33M_3194	2.985e-161	514.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_391517_5	1232410.KI421412_gene166	4.462e-106	372.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH2_k127_391517_3	1168065.DOK_00285	3.179e-133	452.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1J4HU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_391517_15	945713.IALB_1082	1.111e-29	135.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.1.3.1,3.1.3.5,3.1.3.8,3.6.1.45	ko:K01077,ko:K01083,ko:K07004,ko:K11751	ko00230,ko00240,ko00562,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00562,map00730,map00760,map00790,map01100,map01110,map02020	M00126	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R03371,R04620	RC00017,RC00078	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	5_nucleotid_C,Calx-beta,Phytase-like
DTH2_k127_391517_12	1121405.dsmv_2843	5.975e-43	178.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	TIGRFAM CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
DTH2_k127_391517_11	1125863.JAFN01000001_gene583	6.037e-48	193.0	COG1893@1|root,COG1893@2|Bacteria,1R96Z@1224|Proteobacteria,42PU0@68525|delta/epsilon subdivisions,2WK47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DTH2_k127_391517_2	316067.Geob_0166	8.327e-149	481.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria,43UG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
DTH2_k127_391517_9	406817.XNC1_2156	6.446e-76	276.0	COG1022@1|root,COG3321@1|root,COG1022@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
DTH2_k127_391517_7	85643.Tmz1t_2948	2.253e-83	285.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,2VSQQ@28216|Betaproteobacteria,2KXX8@206389|Rhodocyclales	206389|Rhodocyclales	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
DTH2_k127_391517_13	926562.Oweho_1521	4.253e-42	157.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,1IMPQ@117743|Flavobacteriia,2PANX@246874|Cryomorphaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_3961895_2	1379698.RBG1_1C00001G1816	5.962e-51	203.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
DTH2_k127_3961895_3	1123057.P872_18200	3.913e-34	139.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
DTH2_k127_3961895_0	1313301.AUGC01000007_gene678	1.499e-219	691.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_3961895_4	1313301.AUGC01000015_gene1891	2.05e-25	116.0	29N3N@1|root,33SHJ@2|Bacteria,4P1XQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3961895_1	391596.PBAL39_08265	2.1e-161	512.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH2_k127_3973257_8	991.IW20_22820	9.375e-11	73.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,1I4SE@117743|Flavobacteriia,2NYG4@237|Flavobacterium	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
DTH2_k127_3973257_0	929556.Solca_2963	0.0	1293.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DTH2_k127_3973257_3	468059.AUHA01000002_gene74	1.277e-119	419.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH2_k127_3973257_6	362418.IW19_02845	4.643e-47	174.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia,2NVYQ@237|Flavobacterium	976|Bacteroidetes	V	Restriction endonuclease subunit R	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
DTH2_k127_3973257_4	929556.Solca_2398	5.533e-114	378.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DTH2_k127_3973257_9	755732.Fluta_2348	9.875e-11	76.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF4082,DUF4347,HemolysinCabind,SprB
DTH2_k127_3973257_1	1121373.KB903632_gene486	3.35e-161	555.0	COG3291@1|root,COG3405@1|root,COG4447@1|root,COG5520@1|root,COG3291@2|Bacteria,COG3405@2|Bacteria,COG4447@2|Bacteria,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CHU_C,Glyco_hydro_9,HYR,PKD
DTH2_k127_3973257_10	992406.RIA_0564	2.73e-10	69.0	2E2E1@1|root,32XIR@2|Bacteria,4NUDT@976|Bacteroidetes,1IAY1@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3973257_5	743722.Sph21_3540	1.467e-48	176.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
DTH2_k127_3973257_2	485918.Cpin_6574	1.353e-125	410.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,1IQP9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
DTH2_k127_3973257_7	869213.JCM21142_104477	2.924e-42	162.0	COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,47SCF@768503|Cytophagia	976|Bacteroidetes	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
DTH2_k127_3981841_0	1121481.AUAS01000005_gene1834	2.348e-184	582.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia	976|Bacteroidetes	Q	TIGRFAM phytoene desaturase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_3981841_1	1121481.AUAS01000005_gene1833	2.16e-70	245.0	COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,MerR_1
DTH2_k127_3983112_4	1089547.KB913013_gene4310	7.348e-72	262.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_3983112_0	929713.NIASO_17260	0.0	1129.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
DTH2_k127_3983112_3	714943.Mucpa_4505	1.994e-141	460.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1IR94@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_3983112_1	927658.AJUM01000037_gene2182	5.861e-216	680.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,3XJ3E@558415|Marinilabiliaceae	976|Bacteroidetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DTH2_k127_3983112_2	755732.Fluta_1895	1.312e-180	569.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia,2PACA@246874|Cryomorphaceae	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DTH2_k127_3983112_6	1408473.JHXO01000011_gene2963	3.255e-65	232.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DTH2_k127_3983112_7	468059.AUHA01000002_gene69	6.712e-33	134.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3983112_5	1408473.JHXO01000011_gene2965	5.975e-67	235.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,2FM4X@200643|Bacteroidia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
DTH2_k127_3995847_8	903818.KI912268_gene2338	2.109e-12	74.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
DTH2_k127_3995847_4	485913.Krac_2435	3.305e-49	188.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
DTH2_k127_3995847_1	485913.Krac_2434	6.109e-200	655.0	COG1529@1|root,COG1529@2|Bacteria,2G5NF@200795|Chloroflexi	2|Bacteria	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DTH2_k127_3995847_5	511051.CSE_02240	1.588e-41	177.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DTH2_k127_3995847_3	865937.Gilli_3289	2.665e-54	193.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2P6Z2@244698|Gillisia	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
DTH2_k127_3995847_7	714943.Mucpa_0006	1.626e-23	101.0	COG1141@1|root,COG1141@2|Bacteria,4NSRI@976|Bacteroidetes,1IUDU@117747|Sphingobacteriia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
DTH2_k127_3995847_2	1313301.AUGC01000005_gene263	3.183e-191	605.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes	976|Bacteroidetes	O	Collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
DTH2_k127_3995847_6	287.DR97_1916	5.923e-37	144.0	arCOG14922@1|root,32SW8@2|Bacteria,1N0NY@1224|Proteobacteria,1SACT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
DTH2_k127_3995847_0	761193.Runsl_2929	1.566e-246	774.0	COG2070@1|root,COG2070@2|Bacteria,4NEGW@976|Bacteroidetes,47JXU@768503|Cytophagia	976|Bacteroidetes	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4008246_3	1124780.ANNU01000005_gene2433	9.597e-38	149.0	COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,47NE3@768503|Cytophagia	976|Bacteroidetes	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
DTH2_k127_4008246_1	926562.Oweho_0143	4.822e-116	399.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia,2PAM4@246874|Cryomorphaceae	976|Bacteroidetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
DTH2_k127_4008246_0	313606.M23134_07707	1.245e-161	550.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,47M6U@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HTH_18,HisKA_2,Reg_prop,Response_reg,SpoIIE,Y_Y_Y
DTH2_k127_4008246_2	313595.P700755_001778	9.899e-91	308.0	COG2319@1|root,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,1I138@117743|Flavobacteriia,4C43V@83612|Psychroflexus	976|Bacteroidetes	S	Eukaryotic translation initiation factor eIF2A	-	-	-	-	-	-	-	-	-	-	-	-	WD40
DTH2_k127_4053031_2	1313421.JHBV01000008_gene4398	1.152e-96	321.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,1IQEC@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DTH2_k127_4053031_1	743722.Sph21_5231	2.075e-102	341.0	COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,1IQEQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DTH2_k127_4053031_5	153721.MYP_591	6.697e-19	91.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	Peptidase_M56,TonB_C
DTH2_k127_4053031_3	485918.Cpin_0530	1.513e-72	250.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
DTH2_k127_4053031_4	929556.Solca_3404	5.502e-31	124.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,1ITA3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_4053031_0	468059.AUHA01000002_gene980	4.095e-206	646.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_4106144_0	926549.KI421517_gene2595	8.111e-280	861.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,47KGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
DTH2_k127_4106144_1	313606.M23134_07096	4.27e-107	379.0	COG0457@1|root,COG2203@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,47XEM@768503|Cytophagia	2|Bacteria	T	Sigma factor PP2C-like phosphatases	srrB	-	-	ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CBS,HAMP,SpoIIE,TPR_12,TPR_8,Y_Y_Y,dCache_1
DTH2_k127_4106144_3	604354.TSIB_0695	1.069e-46	171.0	arCOG05276@1|root,arCOG05276@2157|Archaea,2Y6V0@28890|Euryarchaeota,2458Q@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4106144_4	1121904.ARBP01000005_gene4514	4.721e-25	111.0	COG0352@1|root,COG0352@2|Bacteria,4NRDR@976|Bacteroidetes,47RRW@768503|Cytophagia	976|Bacteroidetes	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
DTH2_k127_4106144_2	153721.MYP_4583	9.136e-83	282.0	COG0351@1|root,COG0351@2|Bacteria,4NE0F@976|Bacteroidetes,47PMU@768503|Cytophagia	976|Bacteroidetes	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
DTH2_k127_4106144_5	762903.Pedsa_0365	7.245e-07	51.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DTH2_k127_413179_0	984262.SGRA_3562	3.303e-142	476.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
DTH2_k127_413179_1	1158294.JOMI01000009_gene1255	5.706e-24	113.0	2CJ5F@1|root,2ZBRK@2|Bacteria,4NNEN@976|Bacteroidetes,2G2JH@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_413179_2	1410668.JNKC01000006_gene565	3.766e-20	106.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,36DM2@31979|Clostridiaceae	186801|Clostridia	O	PDZ DHR GLGF domain protein	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
DTH2_k127_4142377_2	1121129.KB903359_gene1423	8.851e-66	230.0	COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22WN9@171551|Porphyromonadaceae	976|Bacteroidetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
DTH2_k127_4142377_3	880071.Fleli_0838	1.13e-53	196.0	COG2885@1|root,COG2885@2|Bacteria,4NSJW@976|Bacteroidetes,47REJ@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_4142377_0	927658.AJUM01000037_gene2196	3.613e-76	261.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,2FPBQ@200643|Bacteroidia,3XJ60@558415|Marinilabiliaceae	976|Bacteroidetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH2_k127_4142377_1	1168034.FH5T_18330	1.144e-74	284.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4142377_4	945713.IALB_2304	6.654e-42	160.0	2CBKC@1|root,32RTJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4142377_5	700598.Niako_6325	8.303e-15	78.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1ITJ4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4184114_4	1123037.AUDE01000012_gene104	1.878e-53	192.0	COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,1HXPQ@117743|Flavobacteriia	976|Bacteroidetes	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7	ko:K01505	ko00270,map00270	-	R00997	RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
DTH2_k127_4184114_2	449673.BACSTE_00540	5.169e-79	274.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,4NEER@976|Bacteroidetes,2FM02@200643|Bacteroidia,4AM8V@815|Bacteroidaceae	976|Bacteroidetes	MNU	COG1705 Muramidase (flagellum-specific)	lytG	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,LysM
DTH2_k127_4184114_6	869213.JCM21142_104478	8.9e-39	146.0	COG0732@1|root,COG2827@1|root,COG0732@2|Bacteria,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,47X4H@768503|Cytophagia	976|Bacteroidetes	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_4184114_1	667015.Bacsa_2407	3.348e-163	524.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,2FNNY@200643|Bacteroidia,4ANAU@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
DTH2_k127_4184114_3	1123037.AUDE01000032_gene2256	7.697e-59	209.0	28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0403 family	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
DTH2_k127_4184114_0	866536.Belba_0146	9.256e-241	748.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,47KGI@768503|Cytophagia	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH2_k127_4184114_5	1408473.JHXO01000006_gene1192	4.182e-42	160.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia	976|Bacteroidetes	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_4185762_6	926549.KI421517_gene544	1.955e-25	107.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_4185762_0	925409.KI911562_gene2147	1.42e-198	625.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IP5F@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DTH2_k127_4185762_2	1086011.HJ01_02827	3.348e-85	290.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HX9E@117743|Flavobacteriia,2NU0D@237|Flavobacterium	976|Bacteroidetes	M	Hydrolase Nlp P60	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
DTH2_k127_4185762_4	595460.RRSWK_06974	1.398e-67	249.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
DTH2_k127_4185762_3	269798.CHU_1303	3.269e-76	262.0	COG1225@1|root,COG1225@2|Bacteria,4NXEC@976|Bacteroidetes	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4185762_5	1434325.AZQN01000002_gene1317	1.085e-61	222.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,47NW3@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
DTH2_k127_4185762_1	929562.Emtol_2387	1.875e-88	297.0	COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,47KX8@768503|Cytophagia	976|Bacteroidetes	C	Alanine dehydrogenase/PNT, C-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_4188136_2	1406840.Q763_00980	6.387e-43	159.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1HY41@117743|Flavobacteriia,2NTKI@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH2_k127_4188136_0	888059.HMPREF9071_1514	4.201e-209	657.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,1HXT4@117743|Flavobacteriia,1ER5C@1016|Capnocytophaga	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DTH2_k127_4188136_1	1123248.KB893328_gene922	1.776e-133	434.0	COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1IW53@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_4254796_0	1484460.JSWG01000008_gene1892	1.679e-111	375.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH2_k127_4254796_5	1122176.KB903538_gene1576	1.509e-06	59.0	COG0526@1|root,COG0526@2|Bacteria,4NZHV@976|Bacteroidetes	976|Bacteroidetes	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH2_k127_4254796_3	1408433.JHXV01000041_gene3590	2.321e-22	108.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia,2PBW4@246874|Cryomorphaceae	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DTH2_k127_4254796_1	1189619.pgond44_08812	5.356e-104	341.0	COG0500@1|root,COG0500@2|Bacteria,4PM8S@976|Bacteroidetes,1IJMZ@117743|Flavobacteriia,4C483@83612|Psychroflexus	976|Bacteroidetes	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25,Methyltransf_31,NodS
DTH2_k127_4254796_2	1484460.JSWG01000008_gene1892	7.986e-72	256.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH2_k127_4347828_3	796940.HMPREF9628_00326	5.103e-66	236.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia	186801|Clostridia	KLT	PFAM KWG Leptospira repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
DTH2_k127_4347828_1	1137281.D778_00779	2.673e-72	248.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,1HX5C@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
DTH2_k127_4347828_2	762903.Pedsa_2755	1.623e-68	239.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia	976|Bacteroidetes	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DTH2_k127_4347828_4	1317122.ATO12_23620	2.726e-45	173.0	COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,1HXST@117743|Flavobacteriia,2YJ2E@290174|Aquimarina	976|Bacteroidetes	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH2_k127_4347828_8	1123248.KB893359_gene2118	3.256e-24	107.0	COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1ITUB@117747|Sphingobacteriia	976|Bacteroidetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
DTH2_k127_4347828_9	1313301.AUGC01000004_gene2306	6.185e-21	97.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_4347828_5	153721.MYP_4386	4.944e-33	136.0	2AAU0@1|root,3106Q@2|Bacteria,4NNSV@976|Bacteroidetes,47Q0I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4347828_0	929556.Solca_3454	5.661e-117	380.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1IPN7@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DTH2_k127_4347828_6	929562.Emtol_1928	6.416e-32	136.0	COG0501@1|root,COG4642@1|root,COG0501@2|Bacteria,COG4642@2|Bacteria,4NJPY@976|Bacteroidetes,47K9K@768503|Cytophagia	976|Bacteroidetes	O	Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.	-	-	-	-	-	-	-	-	-	-	-	-	MORN,Peptidase_C14,Peptidase_M48
DTH2_k127_4347828_7	926562.Oweho_2277	1.048e-26	117.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,1HWPN@117743|Flavobacteriia,2PA9G@246874|Cryomorphaceae	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
DTH2_k127_4356805_2	929556.Solca_0677	7.623e-65	226.0	COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia	976|Bacteroidetes	F	uracil phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DTH2_k127_4356805_0	762903.Pedsa_1915	1.142e-164	522.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH2_k127_4356805_3	869213.JCM21142_72764	4.251e-36	140.0	COG1366@1|root,COG1366@2|Bacteria,4NTAB@976|Bacteroidetes	976|Bacteroidetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
DTH2_k127_4356805_4	945713.IALB_2909	1.619e-09	63.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,CarboxypepD_reg,DUF1524,Polysacc_deac_1,SLH
DTH2_k127_4356805_1	1122621.ATZA01000033_gene506	7.998e-105	348.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1IPJ5@117747|Sphingobacteriia	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
DTH2_k127_4375583_0	153721.MYP_4046	9.323e-162	521.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,47JRR@768503|Cytophagia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
DTH2_k127_4375583_1	1122176.KB903532_gene2576	7.243e-92	304.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
DTH2_k127_4399024_0	1408433.JHXV01000027_gene3728	1.34e-161	544.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_4399024_1	714943.Mucpa_4449	3.2e-71	244.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH2_k127_4403347_3	1550091.JROE01000005_gene2071	5.594e-73	257.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_4403347_0	196490.AUEZ01000022_gene912	1.167e-192	608.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,3JSXW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_4403347_7	1123058.KB894251_gene2394	0.0005464	46.0	2DR32@1|root,339YJ@2|Bacteria,4NYM3@976|Bacteroidetes,1I6CH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4403347_5	1349785.BAUG01000037_gene2029	3.257e-57	207.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
DTH2_k127_4403347_4	468059.AUHA01000002_gene1132	4.102e-71	257.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4403347_6	485918.Cpin_0507	9.11e-30	126.0	COG3117@1|root,COG3117@2|Bacteria,4NV8G@976|Bacteroidetes,1IU6N@117747|Sphingobacteriia	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
DTH2_k127_4403347_1	1107311.Q767_02690	2.084e-120	394.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia,2NS6V@237|Flavobacterium	976|Bacteroidetes	I	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_4403347_2	1408433.JHXV01000009_gene1349	1.907e-106	359.0	COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,1IMQG@117743|Flavobacteriia,2PBAV@246874|Cryomorphaceae	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
DTH2_k127_4419164_0	743722.Sph21_2928	2.566e-210	661.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
DTH2_k127_4419164_2	1150600.ADIARSV_0730	1.813e-72	256.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IQZY@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_4419164_1	1122621.ATZA01000008_gene962	2.728e-173	554.0	COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,1IQ7C@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8,Fer4_9
DTH2_k127_4419164_3	1121897.AUGO01000009_gene2879	3.344e-68	233.0	COG0647@1|root,COG0647@2|Bacteria,4NNYH@976|Bacteroidetes,1I2FP@117743|Flavobacteriia,2NVYX@237|Flavobacterium	976|Bacteroidetes	G	Phosphoheptose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4419164_4	865938.Weevi_1441	3.513e-50	180.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,1HXAY@117743|Flavobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG
DTH2_k127_4476873_16	926549.KI421517_gene4124	5.071e-06	50.0	COG2247@1|root,COG3291@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
DTH2_k127_4476873_9	755732.Fluta_3718	2.654e-40	154.0	2BFVS@1|root,32WJ0@2|Bacteria,4PGMC@976|Bacteroidetes,1IFB5@117743|Flavobacteriia,2PC3U@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4476873_11	10228.TriadP37121	3.244e-36	147.0	COG1028@1|root,KOG1208@2759|Eukaryota,38CZD@33154|Opisthokonta,3BACQ@33208|Metazoa	33154|Opisthokonta	Q	NADP-retinol dehydrogenase activity	RDH13	GO:0001523,GO:0001654,GO:0001754,GO:0003407,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0007275,GO:0007399,GO:0007423,GO:0008106,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009653,GO:0009887,GO:0009987,GO:0010817,GO:0010842,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0019866,GO:0022008,GO:0030154,GO:0030182,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0034308,GO:0034754,GO:0042445,GO:0042461,GO:0042462,GO:0042572,GO:0043010,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046530,GO:0048468,GO:0048513,GO:0048592,GO:0048593,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0052650,GO:0055114,GO:0060041,GO:0060042,GO:0065007,GO:0065008,GO:0071704,GO:0090596,GO:1901615	1.1.1.300,2.3.2.27	ko:K04506,ko:K11153,ko:K11161	ko00830,ko01100,ko04013,ko04115,ko04120,ko04310,map00830,map01100,map04013,map04115,map04120,map04310	-	R08379,R08383	RC00649	ko00000,ko00001,ko01000,ko04121	-	-	-	adh_short
DTH2_k127_4476873_4	1131812.JQMS01000001_gene1430	7.681e-76	257.0	COG3040@1|root,COG3040@2|Bacteria,4NNFA@976|Bacteroidetes,1I2GH@117743|Flavobacteriia,2NUFN@237|Flavobacterium	976|Bacteroidetes	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
DTH2_k127_4476873_15	1121373.KB903625_gene3213	3.237e-17	82.0	2E60B@1|root,330PR@2|Bacteria,4NXSG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4476873_8	1131812.JQMS01000001_gene42	1.214e-47	172.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,1I4FW@117743|Flavobacteriia,2NX6I@237|Flavobacterium	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_4476873_12	641524.ADICYQ_3985	1.256e-35	138.0	COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47SAY@768503|Cytophagia	976|Bacteroidetes	P	PFAM Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_4476873_13	929562.Emtol_0588	2.723e-23	100.0	COG0607@1|root,COG0607@2|Bacteria,4PA45@976|Bacteroidetes,47SQ5@768503|Cytophagia	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4476873_0	755732.Fluta_2869	1.449e-213	672.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia,2PA7E@246874|Cryomorphaceae	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
DTH2_k127_4476873_3	1131812.JQMS01000001_gene2967	4.93e-76	259.0	COG3963@1|root,COG3963@2|Bacteria,4PM0M@976|Bacteroidetes,1IJIB@117743|Flavobacteriia,2P0PZ@237|Flavobacterium	976|Bacteroidetes	I	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
DTH2_k127_4476873_7	755732.Fluta_2870	7.472e-48	175.0	COG0730@1|root,COG0730@2|Bacteria,4NTZ8@976|Bacteroidetes,1I2UM@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DTH2_k127_4476873_14	929562.Emtol_0589	2.612e-18	86.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH2_k127_4476873_2	755732.Fluta_2871	1.608e-100	330.0	COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_4476873_6	1538644.KO02_18000	1.78e-51	193.0	COG2253@1|root,COG2253@2|Bacteria,4NME0@976|Bacteroidetes,1IVS1@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
DTH2_k127_4476873_10	1122605.KB893635_gene3502	6.64e-39	150.0	COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1IT89@117747|Sphingobacteriia	976|Bacteroidetes	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
DTH2_k127_4476873_5	1137281.D778_00720	2.488e-65	241.0	COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,1IJ80@117743|Flavobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like,SusD-like_2
DTH2_k127_4476873_1	643867.Ftrac_0991	7.653e-210	690.0	COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47Y5N@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_4485758_0	485918.Cpin_7300	2.896e-169	541.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,1IQIE@117747|Sphingobacteriia	976|Bacteroidetes	S	FAD-dependent dehydrogenase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
DTH2_k127_4485758_1	714943.Mucpa_0527	2.387e-155	501.0	COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,1IQWW@117747|Sphingobacteriia	976|Bacteroidetes	L	DEAD DEAH box helicase domain protein	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_4485758_6	1492737.FEM08_21900	2.983e-45	168.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1I2YH@117743|Flavobacteriia,2NWBM@237|Flavobacterium	976|Bacteroidetes	J	Endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_4485758_5	1047013.AQSP01000119_gene1318	1.197e-55	200.0	COG4843@1|root,COG4843@2|Bacteria,2NPKB@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
DTH2_k127_4485758_7	1121898.Q766_05980	3.04e-45	185.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
DTH2_k127_4485758_4	700598.Niako_3251	1.173e-57	223.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_4485758_8	1131269.AQVV01000002_gene1246	7.548e-45	170.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH2_k127_4485758_3	1341181.FLJC2902T_07220	1.008e-86	294.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia,2NTDT@237|Flavobacterium	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
DTH2_k127_4485758_9	1094466.KQS_06170	0.000194	46.0	2EH3X@1|root,33AVW@2|Bacteria,4NYC0@976|Bacteroidetes,1I6GU@117743|Flavobacteriia,2NXJM@237|Flavobacterium	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4485758_2	1408433.JHXV01000029_gene3104	4.961e-144	484.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
DTH2_k127_4488189_2	1123008.KB905699_gene1957	3.262e-16	81.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,2FMGW@200643|Bacteroidia,22WSS@171551|Porphyromonadaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_4488189_1	926549.KI421517_gene3088	1.009e-86	299.0	COG3021@1|root,COG3021@2|Bacteria,4PKDH@976|Bacteroidetes	976|Bacteroidetes	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_4488189_0	1121101.HMPREF1532_02047	2.11e-108	365.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia,4AK6C@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH2_k127_4580336_2	153721.MYP_3100	5.49e-69	250.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4P298@976|Bacteroidetes,47TIX@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_4580336_0	643867.Ftrac_1464	3.06e-179	565.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_4580336_4	1408813.AYMG01000025_gene2694	1.914e-21	96.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes	976|Bacteroidetes	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
DTH2_k127_4580336_5	1408254.T458_18990	6.991e-08	61.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,4HPRP@91061|Bacilli,26YZK@186822|Paenibacillaceae	91061|Bacilli	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ytlP	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DTH2_k127_4580336_1	1123277.KB893244_gene5122	7.123e-92	306.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,47NXE@768503|Cytophagia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
DTH2_k127_4580336_3	694427.Palpr_0599	7.592e-32	125.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,2FR8Q@200643|Bacteroidia,22XGS@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase, NAD-binding domain protein	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH2_k127_459346_2	1168034.FH5T_06030	3.089e-93	314.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,2FN90@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
DTH2_k127_459346_0	1168034.FH5T_06025	4.662e-105	347.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,2FN7D@200643|Bacteroidia	976|Bacteroidetes	G	Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
DTH2_k127_459346_4	468059.AUHA01000002_gene659	4.855e-53	204.0	2A79D@1|root,30W5Z@2|Bacteria,4NN88@976|Bacteroidetes,1IRXG@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4270
DTH2_k127_459346_1	1313421.JHBV01000030_gene2251	1.139e-96	322.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,1INMV@117747|Sphingobacteriia	976|Bacteroidetes	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH2_k127_459346_3	760192.Halhy_3096	2.647e-89	318.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_461546_3	1453500.AT05_02695	2.01e-46	171.0	COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1I2UT@117743|Flavobacteriia	976|Bacteroidetes	S	thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_461546_0	1123234.AUKI01000020_gene765	1.017e-119	394.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,1HX8D@117743|Flavobacteriia	976|Bacteroidetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
DTH2_k127_461546_2	1380384.JADN01000007_gene1564	6.956e-76	264.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DTH2_k127_461546_1	1122621.ATZA01000002_gene1685	2.91e-102	341.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH2_k127_4642015_3	886379.AEWI01000013_gene2078	5.495e-55	195.0	COG0110@1|root,COG0110@2|Bacteria,4NMZ2@976|Bacteroidetes,2FT0S@200643|Bacteroidia,3XK0Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	acetyltransferase, isoleucine patch superfamily	-	-	-	ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
DTH2_k127_4642015_1	1293054.HSACCH_02443	1.619e-90	311.0	COG0438@1|root,COG0438@2|Bacteria,1UYM0@1239|Firmicutes,24Q93@186801|Clostridia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH2_k127_4642015_0	385682.AFSL01000001_gene1997	2.001e-101	341.0	COG0438@1|root,COG0438@2|Bacteria,4NJ1W@976|Bacteroidetes,2FTR3@200643|Bacteroidia,3XK2C@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_4642015_2	385682.AFSL01000001_gene1998	1.304e-65	237.0	2CAAQ@1|root,331TU@2|Bacteria,4NTCJ@976|Bacteroidetes,2G24Y@200643|Bacteroidia,3XJU8@558415|Marinilabiliaceae	976|Bacteroidetes	S	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_4681686_6	714943.Mucpa_1106	6.875e-130	419.0	COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1INWD@117747|Sphingobacteriia	976|Bacteroidetes	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_4681686_14	929562.Emtol_3657	7.3e-22	110.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,47K12@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
DTH2_k127_4681686_13	1313421.JHBV01000035_gene2493	2.421e-24	113.0	COG0382@1|root,COG0382@2|Bacteria,4NM5C@976|Bacteroidetes,1IR8U@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4681686_2	1408473.JHXO01000001_gene2366	1.255e-191	606.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,2FNJF@200643|Bacteroidia	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DTH2_k127_4681686_0	880526.KE386488_gene1130	3.488e-302	950.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
DTH2_k127_4681686_17	869213.JCM21142_124656	8.882e-08	61.0	2DM48@1|root,31NG2@2|Bacteria,4NQJF@976|Bacteroidetes,47QMX@768503|Cytophagia	976|Bacteroidetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
DTH2_k127_4681686_10	1042376.AFPK01000036_gene1940	7.278e-63	225.0	COG0596@1|root,COG0596@2|Bacteria,4PKUD@976|Bacteroidetes,1IJFD@117743|Flavobacteriia,406G5@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
DTH2_k127_4681686_1	1227739.Hsw_3279	1.852e-194	614.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_4681686_16	1173028.ANKO01000219_gene469	6.248e-13	72.0	COG1872@1|root,COG1872@2|Bacteria,1G935@1117|Cyanobacteria,1HD36@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DTH2_k127_4681686_4	153721.MYP_1661	6.346e-154	505.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,47NYD@768503|Cytophagia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_4681686_8	755732.Fluta_1295	3.959e-85	289.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,1IMQI@117743|Flavobacteriia,2PBDZ@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4681686_11	1124780.ANNU01000019_gene1681	2.185e-60	211.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DTH2_k127_4681686_9	755732.Fluta_2032	2.977e-81	292.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	srrB	-	-	-	-	-	-	-	-	-	-	-	CBS,HAMP,SpoIIE,dCache_1
DTH2_k127_4681686_12	755732.Fluta_1297	9.869e-52	190.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1I176@117743|Flavobacteriia,2PB75@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH2_k127_4681686_3	153721.MYP_1169	1.263e-179	572.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,47JA3@768503|Cytophagia	976|Bacteroidetes	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
DTH2_k127_4681686_5	929562.Emtol_1422	3.494e-144	464.0	COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,47KCS@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase family M20 M25 M40	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DTH2_k127_4681686_7	153721.MYP_1171	6.686e-91	304.0	COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,47JI3@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_4696819_3	1408433.JHXV01000001_gene693	4.092e-39	151.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1IC3X@117743|Flavobacteriia,2PB1K@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_4696819_1	553177.CAPSP0001_1585	1.08e-78	273.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia,1EQZX@1016|Capnocytophaga	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DTH2_k127_4696819_0	153721.MYP_191	6.522e-182	599.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MWA@768503|Cytophagia	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_4696819_2	1515613.HQ37_06195	8.215e-43	157.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,2FKZE@200643|Bacteroidia,22XAY@171551|Porphyromonadaceae	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
DTH2_k127_4758385_1	471854.Dfer_2031	2.751e-128	414.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
DTH2_k127_4758385_6	1358423.N180_02300	1.327e-35	141.0	2C56J@1|root,32YX8@2|Bacteria,4NW78@976|Bacteroidetes,1IYEC@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4758385_4	1270196.JCKI01000004_gene992	6.009e-71	243.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1IXW3@117747|Sphingobacteriia	976|Bacteroidetes	I	NUDIX domain	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
DTH2_k127_4758385_5	926549.KI421517_gene3630	3.865e-42	159.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
DTH2_k127_4758385_3	471854.Dfer_2033	3.491e-74	252.0	COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,47PV8@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	crtZ	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
DTH2_k127_4758385_2	1121481.AUAS01000005_gene1838	4.866e-79	270.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4758385_7	269799.Gmet_2041	1.027e-27	126.0	COG0707@1|root,COG1819@1|root,COG0707@2|Bacteria,COG1819@2|Bacteria,1MW1K@1224|Proteobacteria,42Q6U@68525|delta/epsilon subdivisions,2WMIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CG	PFAM UDP-glucuronosyl UDP-glucosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
DTH2_k127_4758385_0	1408433.JHXV01000006_gene2788	1.65e-228	743.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_4758385_8	925409.KI911562_gene886	0.0002274	44.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1IQ9A@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
DTH2_k127_4767807_3	1121481.AUAS01000040_gene5312	9.36e-14	75.0	COG0789@1|root,COG0789@2|Bacteria,4PNWJ@976|Bacteroidetes,47YI1@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
DTH2_k127_4767807_2	1237149.C900_02304	9.844e-22	110.0	COG1066@1|root,COG1066@2|Bacteria,4P216@976|Bacteroidetes,47THX@768503|Cytophagia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
DTH2_k127_4767807_1	1122176.KB903577_gene4851	1.276e-38	158.0	COG1361@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_476959_1	929556.Solca_2664	2.405e-245	798.0	COG2374@1|root,COG3209@1|root,COG3210@1|root,COG3391@1|root,COG4886@1|root,COG4932@1|root,COG5492@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4886@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_476959_2	700598.Niako_6577	2.142e-174	551.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DTH2_k127_476959_3	926562.Oweho_2456	1.104e-127	424.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,1HYXP@117743|Flavobacteriia,2PACQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Transglycosylase SLT domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
DTH2_k127_476959_0	153721.MYP_4507	0.0	1350.0	COG2373@1|root,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,47K94@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_comp,A2M_recep,CarbopepD_reg_2,Plug,Thiol-ester_cl
DTH2_k127_476959_4	926549.KI421517_gene2905	1.105e-17	84.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,47P9F@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_4775935_1	869213.JCM21142_72674	1.269e-225	712.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,47JK7@768503|Cytophagia	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
DTH2_k127_4775935_13	926562.Oweho_3478	0.0001905	55.0	COG3291@1|root,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,1I7QH@117743|Flavobacteriia	976|Bacteroidetes	O	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB
DTH2_k127_4775935_11	504472.Slin_0619	1.431e-10	75.0	COG3291@1|root,COG3386@1|root,COG5434@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5434@2|Bacteria,4PN9S@976|Bacteroidetes,47TEI@768503|Cytophagia	2|Bacteria	M	Polymorphic membrane protein Chlamydia	-	-	3.2.1.4	ko:K01179,ko:K08738	ko00500,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00500,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R06200,R10151,R11307,R11308	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.6	GH5,GH9	-	CHU_C,GSDH,PKD,SGL
DTH2_k127_4775935_12	926559.JoomaDRAFT_3653	1.887e-10	74.0	COG1874@1|root,COG4447@1|root,COG1874@2|Bacteria,COG4447@2|Bacteria,4PI15@976|Bacteroidetes,1I4K5@117743|Flavobacteriia	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_4775935_9	1501391.LG35_09335	9.625e-56	198.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,2FS3I@200643|Bacteroidia,22UFJ@171550|Rikenellaceae	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DTH2_k127_4775935_10	1410608.JNKX01000045_gene1038	1.208e-40	153.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia,4AQR7@815|Bacteroidaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DTH2_k127_4775935_4	762903.Pedsa_3169	5.187e-100	333.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,1IQSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DTH2_k127_4775935_5	886379.AEWI01000012_gene1157	2.309e-91	308.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,3XJ0S@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor TS	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DTH2_k127_4775935_3	1313301.AUGC01000009_gene1070	2.574e-131	438.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH2_k127_4775935_6	313606.M23134_03708	7.289e-89	298.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DTH2_k127_4775935_2	929556.Solca_0272	5.012e-143	460.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia	976|Bacteroidetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
DTH2_k127_4775935_0	1122605.KB893635_gene3529	1.548e-240	755.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_4775935_7	1410613.JNKF01000001_gene2410	2.754e-86	291.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulatory protein	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_4775935_8	929562.Emtol_2343	6.892e-61	216.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,47Y16@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_4819224_3	1150600.ADIARSV_1895	8.141e-53	193.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IP8S@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH2_k127_4819224_0	485917.Phep_1475	1.113e-115	387.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1IPWM@117747|Sphingobacteriia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_4819224_2	714943.Mucpa_5350	1.206e-58	210.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1ISRH@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH2_k127_4819224_1	742725.HMPREF9450_02306	1.525e-60	214.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,2FKYI@200643|Bacteroidia,22U8G@171550|Rikenellaceae	976|Bacteroidetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH2_k127_4824233_4	714943.Mucpa_4499	5.358e-93	311.0	COG0101@1|root,COG0101@2|Bacteria,4NKT7@976|Bacteroidetes,1IRQ8@117747|Sphingobacteriia	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
DTH2_k127_4824233_2	1094980.Mpsy_0782	5.796e-112	370.0	COG0598@1|root,arCOG02265@2157|Archaea,2XTRP@28890|Euryarchaeota,2N9K8@224756|Methanomicrobia	224756|Methanomicrobia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DTH2_k127_4824233_0	1008457.BAEX01000011_gene1585	2.652e-194	614.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1HXGE@117743|Flavobacteriia,47H3U@76831|Myroides	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DTH2_k127_4824233_8	1122621.ATZA01000011_gene392	4.887e-26	119.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4824233_3	929556.Solca_4292	2.948e-108	354.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1IRA4@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DTH2_k127_4824233_7	509635.N824_11940	5.758e-57	203.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1IRZ1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH2_k127_4824233_6	1550091.JROE01000004_gene1859	6.658e-66	229.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1IRC3@117747|Sphingobacteriia	976|Bacteroidetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
DTH2_k127_4824233_5	1137281.D778_01685	2.986e-89	302.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,1HYNK@117743|Flavobacteriia	976|Bacteroidetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
DTH2_k127_4824233_1	760192.Halhy_1375	9.844e-132	428.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_4987914_1	593750.Metfor_2497	2.057e-120	398.0	COG0457@1|root,arCOG03827@2157|Archaea	2157|Archaea	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
DTH2_k127_4987914_0	593750.Metfor_2496	2.585e-197	625.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,2N95J@224756|Methanomicrobia	224756|Methanomicrobia	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2225	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_4987914_3	593750.Metfor_2495	1.025e-47	174.0	COG0314@1|root,arCOG00533@2157|Archaea,2Y1YG@28890|Euryarchaeota	28890|Euryarchaeota	H	TIGRFAM molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
DTH2_k127_4987914_2	593750.Metfor_2494	3.967e-93	314.0	arCOG02976@1|root,arCOG02976@2157|Archaea,2XT7H@28890|Euryarchaeota,2N9TE@224756|Methanomicrobia	224756|Methanomicrobia	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5069459_0	1408433.JHXV01000029_gene3073	7.871e-211	704.0	COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,1IMQK@117743|Flavobacteriia,2PBES@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25
DTH2_k127_5069459_1	1408433.JHXV01000029_gene3072	1.605e-125	412.0	COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,1HZ3R@117743|Flavobacteriia,2PA70@246874|Cryomorphaceae	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5132332_1	517418.Ctha_1714	3.404e-161	519.0	COG0612@1|root,COG0612@2|Bacteria,1FDGF@1090|Chlorobi	1090|Chlorobi	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_5132332_2	1408813.AYMG01000015_gene5019	1.367e-60	217.0	COG2071@1|root,COG2071@2|Bacteria,4NNEJ@976|Bacteroidetes,1IS4X@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
DTH2_k127_5132332_0	765869.BDW_13495	2.753e-186	584.0	COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,42QF2@68525|delta/epsilon subdivisions,2MTFB@213481|Bdellovibrionales,2WMHR@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH2_k127_5153802_10	593117.TGAM_0970	1.659e-11	71.0	COG0419@1|root,COG2247@1|root,COG2319@1|root,COG5306@1|root,arCOG02559@1|root,arCOG03264@1|root,arCOG00368@2157|Archaea,arCOG00388@2157|Archaea,arCOG02491@2157|Archaea,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG03512@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
DTH2_k127_5153802_2	925409.KI911562_gene1603	1.596e-137	446.0	COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia	976|Bacteroidetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
DTH2_k127_5153802_6	1121904.ARBP01000001_gene5611	1.429e-40	154.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,47R4T@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
DTH2_k127_5153802_1	869213.JCM21142_41583	1.034e-143	466.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DTH2_k127_5153802_4	929556.Solca_1714	2.521e-78	267.0	COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia	976|Bacteroidetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DTH2_k127_5153802_3	929556.Solca_4134	2.004e-107	359.0	COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1J0IW@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
DTH2_k127_5153802_0	153721.MYP_4999	3.058e-169	541.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,47K8V@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DTH2_k127_5153802_8	1317122.ATO12_23450	2.16e-32	133.0	COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,1I2B6@117743|Flavobacteriia,2YH96@290174|Aquimarina	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
DTH2_k127_5153802_7	1453500.AT05_08305	9.554e-37	142.0	29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,1I1Z8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5153802_5	1453500.AT05_00675	1.028e-50	184.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,1HZPW@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
DTH2_k127_5156497_0	1450525.JATV01000004_gene226	8.924e-201	627.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia,2NTEM@237|Flavobacterium	976|Bacteroidetes	Q	Homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
DTH2_k127_5156497_1	1218108.KB908296_gene3043	4.072e-57	201.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1I24B@117743|Flavobacteriia	976|Bacteroidetes	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
DTH2_k127_5156497_2	1121007.AUML01000025_gene28	1.903e-54	203.0	COG1566@1|root,COG1566@2|Bacteria,4NF6F@976|Bacteroidetes,1HZS5@117743|Flavobacteriia,2YHX8@290174|Aquimarina	976|Bacteroidetes	V	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,OEP
DTH2_k127_5185592_3	926562.Oweho_1844	9.789e-110	370.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes,1I79G@117743|Flavobacteriia,2PAI6@246874|Cryomorphaceae	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_5185592_0	945713.IALB_3057	1.181e-268	844.0	COG1505@1|root,COG1505@2|Bacteria	2|Bacteria	E	serine-type exopeptidase activity	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH2_k127_5185592_1	362418.IW19_03240	5.557e-215	683.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia,2NUPC@237|Flavobacterium	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DTH2_k127_5185592_4	1229487.AMYW01000012_gene4270	2.078e-77	286.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2P0KB@237|Flavobacterium	976|Bacteroidetes	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_5185592_6	1122179.KB890415_gene1945	1.991e-14	87.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,1ISKM@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_5185592_5	485918.Cpin_4708	5.269e-41	157.0	COG0791@1|root,COG0791@2|Bacteria,4NMT8@976|Bacteroidetes,1IRY7@117747|Sphingobacteriia	976|Bacteroidetes	M	Nlp p60 protein	-	-	3.4.17.13	ko:K13694,ko:K13695	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
DTH2_k127_5185592_2	1313301.AUGC01000010_gene956	2.185e-150	479.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes	976|Bacteroidetes	G	Aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DTH2_k127_5196193_0	1454007.JAUG01000004_gene2630	4.713e-98	323.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia	976|Bacteroidetes	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DTH2_k127_5196193_1	1123057.P872_11745	8.737e-63	226.0	2B8C0@1|root,321KT@2|Bacteria,4NS0R@976|Bacteroidetes,47RGW@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH2_k127_5196193_2	1408473.JHXO01000007_gene805	6.988e-23	100.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,2FMFI@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DTH2_k127_5198583_0	1122176.KB903560_gene3540	2.795e-134	439.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
DTH2_k127_5198583_4	153721.MYP_506	2.177e-17	85.0	COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,47RWN@768503|Cytophagia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
DTH2_k127_5198583_2	1408433.JHXV01000007_gene2890	7.567e-103	344.0	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,1HXU2@117743|Flavobacteriia,2PBGA@246874|Cryomorphaceae	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
DTH2_k127_5198583_1	926562.Oweho_1411	7.754e-105	349.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1HXB2@117743|Flavobacteriia,2PAPS@246874|Cryomorphaceae	976|Bacteroidetes	M	Male sterility protein	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DTH2_k127_5242955_3	929556.Solca_2597	2.146e-91	310.0	COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia	976|Bacteroidetes	E	Proline dehydrogenase	putA	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DTH2_k127_5242955_0	391596.PBAL39_11297	0.0	1112.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH2_k127_5242955_5	742817.HMPREF9449_02413	1.145e-84	290.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,2FNHW@200643|Bacteroidia,22XE0@171551|Porphyromonadaceae	976|Bacteroidetes	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
DTH2_k127_5242955_1	269798.CHU_0765	2.381e-145	470.0	COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,47KXG@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_5242955_4	1237149.C900_04870	1.262e-90	306.0	COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,47N0Z@768503|Cytophagia	976|Bacteroidetes	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
DTH2_k127_5242955_2	1124780.ANNU01000033_gene1316	3.78e-140	454.0	COG0287@1|root,COG2876@1|root,COG0287@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	aroF	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
DTH2_k127_5242955_6	886377.Murru_3083	6.156e-25	107.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1HXKN@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH2_k127_5284331_0	926562.Oweho_3031	1.351e-140	473.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2PBRD@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Peptidase family M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_5284331_1	509635.N824_18000	4.14e-48	176.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1IQP4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM N-terminal double-transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
DTH2_k127_5340443_2	743722.Sph21_5198	7.617e-91	308.0	COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1IQ3B@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DTH2_k127_5340443_5	398720.MED217_15260	5.531e-33	139.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1HZNB@117743|Flavobacteriia	976|Bacteroidetes	UW	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH2_k127_5340443_4	1353529.M899_2645	2.601e-34	149.0	COG3210@1|root,COG3420@1|root,COG3210@2|Bacteria,COG3420@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH2_k127_5340443_1	926562.Oweho_2008	1.541e-134	437.0	COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,1HX4Z@117743|Flavobacteriia,2PADC@246874|Cryomorphaceae	976|Bacteroidetes	S	Rhodanase C-terminal	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
DTH2_k127_5340443_0	1453498.LG45_04435	3.204e-137	443.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,1HWX0@117743|Flavobacteriia,2NT4H@237|Flavobacterium	976|Bacteroidetes	GM	NAD-dependent epimerase	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_5340443_3	755732.Fluta_1974	4.101e-38	155.0	COG2849@1|root,COG2849@2|Bacteria,4PG65@976|Bacteroidetes,1IMR5@117743|Flavobacteriia,2PBMX@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_5340443_6	1120965.AUBV01000005_gene1729	0.0003039	45.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,47MAW@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DTH2_k127_5346596_0	1227739.Hsw_4223	2.764e-69	239.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_5346596_1	1122176.KB903535_gene1970	2.048e-62	233.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
DTH2_k127_5375496_17	755732.Fluta_0829	1.492e-31	129.0	COG5305@1|root,COG5305@2|Bacteria,4PAK3@976|Bacteroidetes,1IMPV@117743|Flavobacteriia,2PAU3@246874|Cryomorphaceae	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_5375496_13	926562.Oweho_0994	5.472e-56	214.0	2ENVG@1|root,33GGJ@2|Bacteria,4P2K9@976|Bacteroidetes,1I8MZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5375496_7	468059.AUHA01000003_gene1908	1.257e-97	326.0	COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,1IRFD@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_5375496_9	926562.Oweho_1029	3.221e-89	311.0	28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,1I8FZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5375496_4	391596.PBAL39_11537	9.745e-132	433.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,1INWB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
DTH2_k127_5375496_6	1313421.JHBV01000007_gene4280	1.327e-109	375.0	COG0729@1|root,COG0729@2|Bacteria,4PKYQ@976|Bacteroidetes,1IS7K@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
DTH2_k127_5375496_3	1121898.Q766_14730	1.337e-134	434.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia,2NTQ5@237|Flavobacterium	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
DTH2_k127_5375496_15	443144.GM21_2384	2.233e-52	201.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Ank_2,DEAD,DUF4384,Helicase_C,Peptidase_C14,Polysacc_deac_1,TPR_11,TPR_16,TPR_2,TPR_8
DTH2_k127_5375496_12	755732.Fluta_2344	8.062e-59	226.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,2PBF0@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_5375496_10	1270196.JCKI01000001_gene3881	4.077e-89	298.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
DTH2_k127_5375496_11	929556.Solca_4285	5.838e-61	212.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1J0E3@117747|Sphingobacteriia	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase QueD family protein	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_5375496_14	468059.AUHA01000002_gene549	1.912e-53	195.0	COG0775@1|root,COG0775@2|Bacteria,4NQVQ@976|Bacteroidetes,1IT1C@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_5375496_16	313606.M23134_04033	4.25e-32	133.0	COG2340@1|root,COG2340@2|Bacteria,4NW16@976|Bacteroidetes,47SFM@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
DTH2_k127_5375496_2	1380384.JADN01000003_gene383	8.007e-197	629.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia	976|Bacteroidetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH2_k127_5375496_8	1517682.HW49_11215	4.699e-96	324.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,2FR40@200643|Bacteroidia,22XAX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_5375496_1	1121897.AUGO01000006_gene693	8.772e-259	809.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1I02U@117743|Flavobacteriia,2NSVU@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
DTH2_k127_5375496_18	755732.Fluta_0667	6.027e-28	129.0	28ZU6@1|root,2ZMIV@2|Bacteria,4P83G@976|Bacteroidetes,1IMR8@117743|Flavobacteriia,2PBNF@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5375496_5	1408433.JHXV01000007_gene2875	5.533e-114	378.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,1I0D7@117743|Flavobacteriia,2PAGP@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_5375496_0	468059.AUHA01000003_gene1552	1.363e-284	880.0	COG0046@1|root,COG0046@2|Bacteria,4NETY@976|Bacteroidetes,1IR8F@117747|Sphingobacteriia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
DTH2_k127_5418209_5	760192.Halhy_3019	8.388e-08	60.0	COG0457@1|root,COG0457@2|Bacteria,4NJWY@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
DTH2_k127_5418209_0	402612.FP2245	5.134e-166	528.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1HY3S@117743|Flavobacteriia,2NSFS@237|Flavobacterium	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DTH2_k127_5418209_3	1408433.JHXV01000001_gene719	4.689e-57	203.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia,2PAV5@246874|Cryomorphaceae	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH2_k127_5418209_4	717785.HYPMC_2300	1.62e-55	201.0	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,Peptidase_S24
DTH2_k127_5418209_1	485918.Cpin_1159	1.996e-98	324.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1IPXY@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DTH2_k127_5418209_2	909663.KI867150_gene216	5.918e-87	305.0	COG1807@1|root,COG1807@2|Bacteria,1R3XN@1224|Proteobacteria,42P5N@68525|delta/epsilon subdivisions,2WKH2@28221|Deltaproteobacteria,2MQ8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_5426033_2	1121098.HMPREF1534_03418	6.166e-48	179.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,2FMGW@200643|Bacteroidia,4ANE0@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_5426033_0	714943.Mucpa_0023	1.679e-180	573.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1INSD@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_5426033_1	929556.Solca_2462	1.196e-116	389.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQAH@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_5472008_0	386456.JQKN01000001_gene2206	1.514e-223	722.0	COG2201@1|root,arCOG04921@2157|Archaea,2Y7RM@28890|Euryarchaeota	28890|Euryarchaeota	N	MCP methyltransferase, CheR-type	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS,PAS_10,PAS_4,PAS_9
DTH2_k127_5472008_1	237368.SCABRO_01740	4.263e-32	134.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1
DTH2_k127_548809_0	755732.Fluta_0625	1.08e-181	577.0	COG0436@1|root,COG0436@2|Bacteria,4NFPR@976|Bacteroidetes,1HY08@117743|Flavobacteriia,2PBFC@246874|Cryomorphaceae	976|Bacteroidetes	H	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_548809_1	929556.Solca_1911	3.386e-133	435.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia	976|Bacteroidetes	M	mannose-1-phosphate guanylyltransferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_548809_2	1189619.pgond44_14603	3.654e-10	71.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M
DTH2_k127_5538716_2	1380384.JADN01000003_gene416	1.604e-145	465.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
DTH2_k127_5538716_3	926549.KI421517_gene3528	1.451e-110	363.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,47XP8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
DTH2_k127_5538716_1	694427.Palpr_1027	9.399e-160	526.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,2G31C@200643|Bacteroidia,231KH@171551|Porphyromonadaceae	976|Bacteroidetes	M	phosphoglycerol transferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_5538716_0	1237149.C900_04127	4.924e-166	531.0	COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,47JD1@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM flavoprotein, HI0933 family	yhiN	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH2_k127_5538716_6	929562.Emtol_4256	2.527e-99	333.0	COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,47KDR@768503|Cytophagia	976|Bacteroidetes	S	S1 domain	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
DTH2_k127_5538716_8	1048983.EL17_10130	1.339e-75	255.0	COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,47P72@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DTH2_k127_5538716_4	929703.KE386491_gene2542	4.746e-106	349.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,47JB0@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_5538716_7	153721.MYP_205	9.292e-86	286.0	COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,47PI0@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH2_k127_5538716_5	1313421.JHBV01000032_gene1573	1.842e-105	353.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
DTH2_k127_5541674_4	762903.Pedsa_1821	1.263e-10	66.0	COG2353@1|root,COG2353@2|Bacteria,4PP3D@976|Bacteroidetes	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5541674_1	468059.AUHA01000002_gene793	6.644e-141	455.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_5541674_3	1121104.AQXH01000001_gene1193	4.651e-70	245.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH2_k127_5541674_0	1408433.JHXV01000001_gene706	4.952e-172	546.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,1HY1Q@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_5541674_2	1408813.AYMG01000001_gene3366	2.11e-140	451.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1IQ44@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH2_k127_5544935_2	1270196.JCKI01000008_gene1635	5.065e-06	59.0	COG2755@1|root,COG2755@2|Bacteria,4NYSV@976|Bacteroidetes,1IVDY@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH2_k127_5544935_0	1408433.JHXV01000023_gene3302	4.976e-98	341.0	COG3291@1|root,COG3291@2|Bacteria,4PBW3@976|Bacteroidetes,1ICPP@117743|Flavobacteriia,2PBJ2@246874|Cryomorphaceae	976|Bacteroidetes	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
DTH2_k127_5544935_1	323261.Noc_1226	3.942e-29	124.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,1T2R5@1236|Gammaproteobacteria,1WZ7X@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5548925_0	1408433.JHXV01000014_gene3668	1.55e-108	373.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
DTH2_k127_5548925_1	1450525.JATV01000005_gene343	2.05e-41	158.0	COG1670@1|root,COG1670@2|Bacteria,4NNT2@976|Bacteroidetes,1I3AA@117743|Flavobacteriia,2NVAR@237|Flavobacterium	976|Bacteroidetes	J	Acetyltransferase	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
DTH2_k127_5548925_2	938709.AUSH02000016_gene825	4.852e-21	97.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes	976|Bacteroidetes	CO	Cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH2_k127_5554820_3	1286632.P278_02130	1.359e-64	224.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1HY06@117743|Flavobacteriia	976|Bacteroidetes	D	atp-binding protein	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DTH2_k127_5554820_0	1408473.JHXO01000011_gene3152	1.048e-190	633.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
DTH2_k127_5554820_2	153721.MYP_768	2.206e-70	260.0	COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,47JSU@768503|Cytophagia	976|Bacteroidetes	H	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
DTH2_k127_5554820_1	929562.Emtol_2637	4.402e-75	260.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,47JKE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_5554820_4	1121957.ATVL01000006_gene3184	1.751e-64	239.0	2C5KB@1|root,2ZCDW@2|Bacteria,4NMNY@976|Bacteroidetes,47PDN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5554820_6	153721.MYP_528	8.714e-13	73.0	2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes,47SN3@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
DTH2_k127_5554820_5	1168034.FH5T_05415	2.551e-14	72.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH2_k127_5590245_2	880073.Calab_1858	1.948e-150	497.0	COG1361@1|root,COG4447@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,TM_helix
DTH2_k127_5590245_25	880073.Calab_3510	7.326e-13	82.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.96	ko:K01361,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,DUF11,Gram_pos_anchor,Peptidase_S8,SLH,SdrD_B,fn3_5
DTH2_k127_5590245_3	743722.Sph21_0678	6.331e-149	478.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_5590245_14	755732.Fluta_2398	1.187e-55	209.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_5590245_22	1202532.FF52_18930	1.41e-20	109.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NSSE@237|Flavobacterium	976|Bacteroidetes	O	gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB,fn3
DTH2_k127_5590245_16	1121898.Q766_05980	2.014e-54	220.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
DTH2_k127_5590245_24	700598.Niako_4555	1.608e-13	85.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Beta_helix,Big_2,CBM26,CBM53,CBM_35,CBM_X2,CHB_HEX_C_1,Flg_new,Glyco_hydro_43,Peptidase_C1,RicinB_lectin_2,SLH
DTH2_k127_5590245_7	1408433.JHXV01000005_gene2335	1.66e-94	331.0	COG1404@1|root,COG1404@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_5590245_21	755732.Fluta_3566	6.282e-23	113.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,1HYIP@117743|Flavobacteriia,2PBI8@246874|Cryomorphaceae	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5590245_20	1123276.KB893270_gene4742	2.434e-25	112.0	2DQ3Y@1|root,334MD@2|Bacteria,4PPRS@976|Bacteroidetes,47YR5@768503|Cytophagia	976|Bacteroidetes	S	Putative beta-lactamase-inhibitor-like, PepSY-like	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
DTH2_k127_5590245_4	693979.Bache_3205	2.288e-143	484.0	COG1629@1|root,COG4932@1|root,COG4771@2|Bacteria,COG4932@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia,4APIA@815|Bacteroidaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
DTH2_k127_5590245_10	1296416.JACB01000019_gene4901	4.268e-86	299.0	COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1HZ62@117743|Flavobacteriia,2YI31@290174|Aquimarina	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_5590245_9	313606.M23134_02433	2.745e-89	301.0	COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,47JTK@768503|Cytophagia	976|Bacteroidetes	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_5590245_5	431947.PGN_1970	6.217e-125	428.0	COG1974@1|root,COG1974@2|Bacteria,4PKGW@976|Bacteroidetes,2FXSG@200643|Bacteroidia,2323F@171551|Porphyromonadaceae	976|Bacteroidetes	KT	cysteine-type peptidase activity	-	-	3.4.22.37	ko:K08589	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cleaved_Adhesin,DUF2436,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_5590245_0	743722.Sph21_5232	2.94e-280	867.0	COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,1IP4E@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DTH2_k127_5590245_18	926549.KI421517_gene2267	3.105e-42	161.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DTH2_k127_5590245_17	926562.Oweho_2371	1.087e-46	174.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia,2PB2M@246874|Cryomorphaceae	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
DTH2_k127_5590245_23	1347393.HG726020_gene845	1.978e-16	81.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DTH2_k127_5590245_8	929713.NIASO_14070	2.684e-92	315.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1IPTF@117747|Sphingobacteriia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DTH2_k127_5590245_1	1168034.FH5T_04685	3.461e-187	631.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia	976|Bacteroidetes	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_5590245_12	468059.AUHA01000002_gene757	5.796e-64	222.0	COG2185@1|root,COG2185@2|Bacteria,4NNXP@976|Bacteroidetes,1ISIG@117747|Sphingobacteriia	976|Bacteroidetes	I	COGs COG2185 Methylmalonyl-CoA mutase C-terminal domain subunit (cobalamin-binding)	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
DTH2_k127_5590245_29	1121405.dsmv_1533	0.0008684	44.0	2EGU9@1|root,33AKF@2|Bacteria,1NJPN@1224|Proteobacteria	1224|Proteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
DTH2_k127_5590245_6	1279009.ADICEAN_00292	1.358e-95	321.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DTH2_k127_5590245_13	1121904.ARBP01000007_gene2943	8.608e-57	217.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5590245_26	153721.MYP_3850	1.011e-10	76.0	COG3291@1|root,COG3291@2|Bacteria,4NS69@976|Bacteroidetes,47TT9@768503|Cytophagia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_5590245_19	926562.Oweho_3290	5.219e-36	158.0	COG3291@1|root,COG3291@2|Bacteria,4PI0H@976|Bacteroidetes,1IGQE@117743|Flavobacteriia,2PBJ6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_5590245_28	491205.JARQ01000009_gene3377	7.387e-07	63.0	COG3291@1|root,COG3291@2|Bacteria,4NU74@976|Bacteroidetes,1I4JY@117743|Flavobacteriia,3ZT65@59732|Chryseobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5590245_15	755732.Fluta_2899	9.374e-55	221.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_5590245_11	1280390.CBQR020000128_gene3196	1.58e-64	228.0	COG5184@1|root,COG5184@2|Bacteria,1TS5I@1239|Firmicutes,4HFME@91061|Bacilli,26W6M@186822|Paenibacillaceae	91061|Bacilli	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2,SLH,fn3
DTH2_k127_5599901_2	755732.Fluta_0165	1.7e-16	80.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,1I1XK@117743|Flavobacteriia,2PB63@246874|Cryomorphaceae	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
DTH2_k127_5599901_1	1305737.JAFX01000001_gene3672	1.99e-102	340.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,47KXZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DTH2_k127_5599901_0	929556.Solca_3225	1.35e-120	400.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia	976|Bacteroidetes	EP	PFAM Binding-protein-dependent transport system inner membrane component	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DTH2_k127_5599901_3	1347342.BN863_31500	3.092e-08	56.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1HXPD@117743|Flavobacteriia	976|Bacteroidetes	M	probably involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_5625791_2	1121898.Q766_16805	4.917e-139	446.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia,2NTFX@237|Flavobacterium	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
DTH2_k127_5625791_0	172045.KS04_08905	1.093e-178	568.0	COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1HZ69@117743|Flavobacteriia,34PNJ@308865|Elizabethkingia	976|Bacteroidetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DTH2_k127_5625791_3	1123008.KB905695_gene2619	3.166e-133	432.0	COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,2FMFQ@200643|Bacteroidia,22WB3@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_5625791_1	1121898.Q766_16790	1.324e-149	477.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1HWUM@117743|Flavobacteriia,2NSU2@237|Flavobacterium	976|Bacteroidetes	E	belongs to the imidazoleglycerol-phosphate dehydratase family	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
DTH2_k127_5669172_0	1121899.Q764_12950	1.2e-225	707.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia,2NU4S@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH2_k127_5669172_9	762903.Pedsa_3585	2.15e-35	143.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1IRVW@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
DTH2_k127_5669172_5	485918.Cpin_0373	2.898e-69	243.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
DTH2_k127_5669172_10	926559.JoomaDRAFT_1220	4.501e-26	115.0	COG0352@1|root,COG0352@2|Bacteria,4NRDR@976|Bacteroidetes,1I374@117743|Flavobacteriia	976|Bacteroidetes	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
DTH2_k127_5669172_2	1121904.ARBP01000011_gene1509	3.31e-182	575.0	COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,47JNT@768503|Cytophagia	976|Bacteroidetes	C	Thiazole biosynthesis protein ThiH	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
DTH2_k127_5669172_7	1121104.AQXH01000002_gene672	5.098e-44	164.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5669172_3	1211813.CAPH01000018_gene1019	5.471e-153	493.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia,22U3K@171550|Rikenellaceae	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DTH2_k127_5669172_1	927658.AJUM01000037_gene2082	2.408e-211	671.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,2FMH0@200643|Bacteroidia,3XJTQ@558415|Marinilabiliaceae	976|Bacteroidetes	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_5669172_11	1358423.N180_16970	6.727e-15	84.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1IX6S@117747|Sphingobacteriia	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
DTH2_k127_5669172_8	1123277.KB893184_gene3957	1.027e-35	140.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,47PPW@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD TolR	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH2_k127_5669172_6	743722.Sph21_2226	8.881e-55	200.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,1IQAP@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_5669172_4	1122176.KB903536_gene1754	6.371e-70	251.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH2_k127_5672550_4	929556.Solca_2248	3.18e-11	67.0	COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia	976|Bacteroidetes	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
DTH2_k127_5672550_3	391596.PBAL39_23242	3.443e-21	95.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1ITVV@117747|Sphingobacteriia	976|Bacteroidetes	C	ATP synthase	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
DTH2_k127_5672550_0	96561.Dole_3112	1.812e-90	316.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,431QP@68525|delta/epsilon subdivisions,2WWXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5672550_2	760192.Halhy_3096	5.198e-76	278.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_5672550_5	1268240.ATFI01000018_gene60	8.066e-07	51.0	2A76E@1|root,30W2E@2|Bacteria,4P9FC@976|Bacteroidetes,2FZNB@200643|Bacteroidia,4AUSK@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5672550_1	1237149.C900_02885	9.63e-83	278.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
DTH2_k127_5678257_3	1313301.AUGC01000001_gene1815	3.315e-17	85.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes	976|Bacteroidetes	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH2_k127_5678257_0	1121373.KB903636_gene784	2.552e-100	331.0	COG0702@1|root,COG0702@2|Bacteria,4NGMR@976|Bacteroidetes,47NYS@768503|Cytophagia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_5678257_1	391603.FBALC1_02127	4.582e-43	162.0	COG0454@1|root,COG0456@2|Bacteria,4NQDY@976|Bacteroidetes,1I23P@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
DTH2_k127_5678257_2	926562.Oweho_1135	5.791e-36	139.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1HX49@117743|Flavobacteriia,2PA7Q@246874|Cryomorphaceae	976|Bacteroidetes	GV	PFAM Glycosyl hydrolase family 3 N terminal domain	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_5681628_1	468059.AUHA01000003_gene1685	4.931e-77	263.0	COG2271@1|root,COG2271@2|Bacteria,4NG3R@976|Bacteroidetes,1IW8Q@117747|Sphingobacteriia	976|Bacteroidetes	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
DTH2_k127_5681628_0	926549.KI421517_gene2264	2.96e-172	555.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,47JP2@768503|Cytophagia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH2_k127_5701795_1	269798.CHU_3722	3.675e-25	108.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,47QBK@768503|Cytophagia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
DTH2_k127_5701795_2	644282.Deba_2169	2.229e-11	73.0	COG2890@1|root,COG2890@2|Bacteria,1RH92@1224|Proteobacteria	1224|Proteobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5701795_0	1004149.AFOE01000004_gene2344	4.775e-79	269.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1HWYD@117743|Flavobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH2_k127_5723796_10	908612.HMPREF9720_2266	5.062e-10	66.0	COG0683@1|root,COG1388@1|root,COG0683@2|Bacteria,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,2FNR1@200643|Bacteroidia,22UG1@171550|Rikenellaceae	976|Bacteroidetes	EM	Lysin motif	lysM	-	-	-	-	-	-	-	-	-	-	-	ANF_receptor,LysM,Peripla_BP_6
DTH2_k127_5723796_0	1121904.ARBP01000016_gene5186	9.545e-249	776.0	COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
DTH2_k127_5723796_1	1406840.Q763_07055	4.533e-140	449.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia,2NSPM@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
DTH2_k127_5723796_7	1122226.AUHX01000005_gene2435	6.494e-39	153.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1I2XJ@117743|Flavobacteriia	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DTH2_k127_5723796_4	1121912.AUHD01000001_gene2523	1.609e-77	263.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DTH2_k127_5723796_8	1122179.KB890420_gene2490	3.537e-17	89.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
DTH2_k127_5723796_5	926562.Oweho_3344	8.153e-74	256.0	COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,1HWTY@117743|Flavobacteriia	976|Bacteroidetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
DTH2_k127_5723796_3	1380384.JADN01000006_gene2412	9.849e-99	329.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,1HXJ4@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DTH2_k127_5723796_6	1286632.P278_21050	2.335e-71	245.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,1HWSC@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
DTH2_k127_5723796_2	1506583.JQJY01000004_gene2519	4.378e-99	335.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia,2NTHD@237|Flavobacterium	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
DTH2_k127_5723796_9	391587.KAOT1_10506	3.062e-13	70.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1HYBQ@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DTH2_k127_5737082_2	1237149.C900_04027	7.288e-30	122.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
DTH2_k127_5737082_3	1341181.FLJC2902T_24600	1.179e-19	91.0	2E46C@1|root,32Z2A@2|Bacteria,4NV81@976|Bacteroidetes,1I537@117743|Flavobacteriia,2NXAP@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5737082_0	468059.AUHA01000002_gene983	3.773e-174	558.0	COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
DTH2_k127_5737082_4	468059.AUHA01000002_gene982	4.22e-16	83.0	2DRKN@1|root,33C6H@2|Bacteria,4NZAT@976|Bacteroidetes,1ITIX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5737082_1	926549.KI421517_gene1345	1.875e-125	406.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DTH2_k127_5759211_2	1121904.ARBP01000007_gene2943	2.673e-55	210.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5759211_1	1034807.FBFL15_1300	1.42e-70	248.0	COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,1HXCW@117743|Flavobacteriia,2NTBE@237|Flavobacterium	976|Bacteroidetes	EG	permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_5759211_0	643867.Ftrac_0021	2.831e-193	613.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
DTH2_k127_5811903_3	1121129.KB903370_gene139	6.964e-129	419.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,2FMMT@200643|Bacteroidia,22VZH@171551|Porphyromonadaceae	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DTH2_k127_5811903_10	391596.PBAL39_23862	3.748e-15	76.0	2AC5I@1|root,311PY@2|Bacteria,4PGIV@976|Bacteroidetes,1ITTN@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
DTH2_k127_5811903_7	313603.FB2170_15936	4.133e-26	108.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia,2PHRT@252356|Maribacter	976|Bacteroidetes	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DTH2_k127_5811903_4	1392490.JHZX01000001_gene783	7.002e-127	421.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,1HZX1@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_5811903_8	153721.MYP_1259	1.097e-24	105.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,47R5P@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
DTH2_k127_5811903_0	485917.Phep_3005	1.968e-195	620.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1IQW8@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_5811903_2	755732.Fluta_3405	7.041e-133	428.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia,2PBB2@246874|Cryomorphaceae	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH2_k127_5811903_1	1168289.AJKI01000035_gene3580	2.857e-146	477.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae	976|Bacteroidetes	O	Trypsin	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
DTH2_k127_5811903_5	929556.Solca_3770	2.91e-86	292.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1IP6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
DTH2_k127_5811903_11	1300143.CCAV010000003_gene2351	2.587e-08	66.0	28WE7@1|root,2ZIEF@2|Bacteria,4NMCV@976|Bacteroidetes,1I5VT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5811903_9	1122931.AUAE01000027_gene2379	3.2e-16	87.0	2BPCS@1|root,32I4T@2|Bacteria,4NRC6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5811903_6	620914.JH621249_gene3368	1.646e-50	196.0	COG0419@1|root,COG0419@2|Bacteria,4NEZ2@976|Bacteroidetes,1HXTM@117743|Flavobacteriia	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	MukB
DTH2_k127_5859468_5	1358423.N180_16795	1.328e-15	78.0	COG0491@1|root,COG0491@2|Bacteria,4NINV@976|Bacteroidetes,1IS2X@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_5859468_2	755732.Fluta_1284	2.024e-121	416.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_5859468_1	153721.MYP_4581	2.885e-123	400.0	COG2022@1|root,COG2022@2|Bacteria,4NDWY@976|Bacteroidetes,47JAC@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
DTH2_k127_5859468_3	1121286.AUMT01000004_gene911	4.317e-84	283.0	COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,1HYFU@117743|Flavobacteriia,3ZPNJ@59732|Chryseobacterium	976|Bacteroidetes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
DTH2_k127_5859468_7	1313421.JHBV01000022_gene4651	0.000987	53.0	2F6V4@1|root,33ZB8@2|Bacteria,4P45W@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5859468_4	984262.SGRA_2693	1.031e-34	154.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_5859468_6	1121930.AQXG01000004_gene2868	5.898e-13	83.0	COG1572@1|root,COG2911@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG4733@2|Bacteria,4NYS6@976|Bacteroidetes,1IZ9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5859468_0	1229487.AMYW01000035_gene3114	2.119e-124	404.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,2NUW9@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DTH2_k127_5869636_2	1121373.KB903629_gene362	1.735e-27	122.0	COG0457@1|root,COG0457@2|Bacteria	1121373.KB903629_gene362|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5869636_0	700598.Niako_0416	1.631e-115	380.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH2_k127_5869636_1	755732.Fluta_0797	1.064e-58	216.0	COG2208@1|root,COG2208@2|Bacteria,4NHV8@976|Bacteroidetes	976|Bacteroidetes	KT	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,SpoIIE
DTH2_k127_5967331_1	929556.Solca_4267	1.262e-90	306.0	COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,1IXJ7@117747|Sphingobacteriia	976|Bacteroidetes	J	PFAM SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_5967331_0	984262.SGRA_1441	1.253e-117	385.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH2_k127_5967331_2	926549.KI421517_gene579	1.412e-72	252.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
DTH2_k127_597170_4	485918.Cpin_2594	2.528e-21	94.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1IZDH@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_597170_0	1123277.KB893207_gene384	7.195e-317	979.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47JMW@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH2_k127_597170_3	1233950.IW22_04520	1.915e-45	168.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,3ZS40@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
DTH2_k127_597170_2	290315.Clim_1707	5.396e-182	576.0	COG0027@1|root,COG0027@2|Bacteria,1FDB8@1090|Chlorobi	1090|Chlorobi	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
DTH2_k127_597170_1	643867.Ftrac_3705	3.195e-194	613.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_597170_6	641526.ADIWIN_3141	0.0007551	51.0	COG4886@1|root,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1HYVY@117743|Flavobacteriia	976|Bacteroidetes	I	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_597170_5	313606.M23134_06902	1.864e-18	97.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,Peptidase_M43
DTH2_k127_6017637_1	1408473.JHXO01000004_gene166	7.294e-97	331.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
DTH2_k127_6017637_0	468059.AUHA01000006_gene3033	1.119e-200	641.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1IPDM@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
DTH2_k127_6036090_15	929556.Solca_0404	1.303e-05	50.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IT0W@117747|Sphingobacteriia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
DTH2_k127_6036090_2	1189620.AJXL01000006_gene2418	2.752e-204	646.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1HY25@117743|Flavobacteriia,2NSIM@237|Flavobacterium	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH2_k127_6036090_0	1166018.FAES_1660	1.605e-245	765.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M5W@768503|Cytophagia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
DTH2_k127_6036090_8	755732.Fluta_0384	3.043e-79	290.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_6036090_6	153721.MYP_243	1.557e-134	457.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia	976|Bacteroidetes	MU	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_11,TPR_16
DTH2_k127_6036090_3	929556.Solca_1867	8.258e-179	569.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bfmBB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_6036090_10	215803.DB30_7175	9.973e-74	249.0	COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria,438KW@68525|delta/epsilon subdivisions,2X3V9@28221|Deltaproteobacteria,2YX7P@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_6036090_11	236814.IX39_04265	7.865e-65	227.0	COG1905@1|root,COG1905@2|Bacteria,4NHIQ@976|Bacteroidetes,1HZPI@117743|Flavobacteriia,3ZQR9@59732|Chryseobacterium	976|Bacteroidetes	C	NADH-quinone oxidoreductase subunit E	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
DTH2_k127_6036090_1	485917.Phep_4077	4.022e-228	712.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1INS2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
DTH2_k127_6036090_4	714943.Mucpa_3124	9.186e-165	524.0	COG1034@1|root,COG1034@2|Bacteria,4NH3P@976|Bacteroidetes,1IR1J@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,NADH-G_4Fe-4S_3
DTH2_k127_6036090_5	509635.N824_12895	1.122e-156	500.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1IR49@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH2_k127_6036090_9	755732.Fluta_1965	5.943e-77	261.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I2F9@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
DTH2_k127_6036090_12	929556.Solca_3731	6.523e-51	185.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1ISVB@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH2_k127_6036090_13	929556.Solca_3730	9.842e-38	143.0	COG0713@1|root,COG0713@2|Bacteria,4NTBP@976|Bacteroidetes,1ISXN@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH2_k127_6036090_7	1270196.JCKI01000001_gene3982	1.074e-100	334.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
DTH2_k127_6044333_1	385682.AFSL01000060_gene1816	1.247e-86	295.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,2FM17@200643|Bacteroidia,3XJE8@558415|Marinilabiliaceae	976|Bacteroidetes	D	FtsX-like permease family	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
DTH2_k127_6044333_3	1168034.FH5T_04995	1.651e-16	82.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 9.82	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
DTH2_k127_6044333_0	1120966.AUBU01000016_gene3077	2.088e-89	302.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DTH2_k127_6044333_2	641526.ADIWIN_1658	3.532e-42	157.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
DTH2_k127_607058_2	1123277.KB893195_gene5606	8.217e-119	387.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,47MWF@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH2_k127_607058_3	1392498.JQLH01000001_gene1022	8.419e-33	141.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia,2PG97@252356|Maribacter	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_607058_1	1237149.C900_00478	9.018e-158	503.0	COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,47K90@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH2_k127_607058_0	1313421.JHBV01000020_gene5217	2.65e-172	553.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
DTH2_k127_607058_4	745718.JADT01000012_gene875	3.287e-14	81.0	COG1629@1|root,COG1629@2|Bacteria,4PKUT@976|Bacteroidetes,1IJFW@117743|Flavobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_6125951_1	1121878.AUGL01000028_gene2088	8.208e-35	137.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,1RZTV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_6125951_0	313606.M23134_05335	7.65e-163	544.0	COG1372@1|root,COG4447@1|root,COG5184@1|root,COG5492@1|root,COG1372@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
DTH2_k127_6187485_3	443143.GM18_1438	7.266e-21	93.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_6187485_0	385682.AFSL01000047_gene524	6.077e-61	226.0	COG0438@1|root,COG0438@2|Bacteria,4NPDT@976|Bacteroidetes,2FSPY@200643|Bacteroidia	976|Bacteroidetes	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH2_k127_6187485_1	742767.HMPREF9456_02164	7.832e-52	194.0	COG0463@1|root,COG0463@2|Bacteria,4NQNJ@976|Bacteroidetes,2FQQ6@200643|Bacteroidia,22YZ0@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_6187485_2	771875.Ferpe_0117	4.869e-29	119.0	COG0110@1|root,COG0110@2|Bacteria,2GCXC@200918|Thermotogae	200918|Thermotogae	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.209	ko:K21379	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
DTH2_k127_6200325_0	755732.Fluta_0704	2.402e-82	291.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_6200325_1	1296416.JACB01000032_gene2291	5.375e-49	181.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1I0QN@117743|Flavobacteriia,2YJJY@290174|Aquimarina	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_6234217_0	926562.Oweho_3365	1.102e-251	786.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,1HWNY@117743|Flavobacteriia,2PAF4@246874|Cryomorphaceae	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_6234217_1	1121007.AUML01000028_gene2104	1.789e-164	524.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2YGYJ@290174|Aquimarina	976|Bacteroidetes	L	DNA Topoisomerase IV	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH2_k127_6245633_0	929556.Solca_2578	5.458e-182	586.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_6245633_2	714943.Mucpa_6139	1.099e-26	112.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITST@117747|Sphingobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DTH2_k127_6245633_3	1150600.ADIARSV_1734	2.545e-26	112.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1IT9C@117747|Sphingobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DTH2_k127_6245633_1	755732.Fluta_1216	1.233e-115	394.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_6251274_1	1163407.UU7_03752	2.464e-21	106.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,1RQPC@1236|Gammaproteobacteria,1X4JF@135614|Xanthomonadales	135614|Xanthomonadales	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
DTH2_k127_6251274_0	1237149.C900_01868	4.79e-46	185.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6254004_6	755732.Fluta_1178	1.27e-41	159.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1HWR6@117743|Flavobacteriia,2PATF@246874|Cryomorphaceae	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, transmembrane domain	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
DTH2_k127_6254004_2	1408433.JHXV01000014_gene3655	3.813e-119	394.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,1HY1X@117743|Flavobacteriia,2PAAV@246874|Cryomorphaceae	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6254004_5	929556.Solca_3365	4.142e-44	169.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1IRVN@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH2_k127_6254004_4	1453505.JASY01000002_gene2906	9.915e-54	193.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1HXN6@117743|Flavobacteriia,2NSCW@237|Flavobacterium	976|Bacteroidetes	C	membrane	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
DTH2_k127_6254004_1	1416760.AYMS01000051_gene254	8.992e-237	738.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1HY9P@117743|Flavobacteriia,47H3X@76831|Myroides	976|Bacteroidetes	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH2_k127_6254004_0	269798.CHU_2212	0.0	1041.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
DTH2_k127_6254004_3	929704.Myrod_2263	6.215e-103	350.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1HXD9@117743|Flavobacteriia,47GXW@76831|Myroides	976|Bacteroidetes	C	Class III cytochrome C family	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
DTH2_k127_6254004_7	1408473.JHXO01000001_gene2450	9.189e-23	102.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_6265621_2	402612.FP0280	4.851e-05	50.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,2NU61@237|Flavobacterium	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
DTH2_k127_6265621_1	880071.Fleli_0994	7.428e-07	58.0	COG4083@1|root,COG4083@2|Bacteria,4NM52@976|Bacteroidetes,47SA3@768503|Cytophagia	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	groEL	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
DTH2_k127_6265621_0	945713.IALB_2618	1.375e-186	593.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_6282007_2	1121904.ARBP01000001_gene5958	2.884e-61	214.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_6282007_3	926549.KI421517_gene2443	3.279e-46	171.0	COG1576@1|root,COG1576@2|Bacteria,4NMFP@976|Bacteroidetes,47Q9Z@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
DTH2_k127_6282007_4	485918.Cpin_0474	3.109e-18	89.0	2E4AG@1|root,33IJ2@2|Bacteria,4P9RI@976|Bacteroidetes,1IUJQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
DTH2_k127_6282007_1	485917.Phep_1198	7.907e-106	352.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,1INNF@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
DTH2_k127_6282007_0	1124780.ANNU01000024_gene3108	5.78e-184	581.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DTH2_k127_6329391_5	929556.Solca_0531	1.816e-100	334.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_6329391_6	1121957.ATVL01000009_gene1392	1.51e-40	156.0	COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia	976|Bacteroidetes	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DTH2_k127_6329391_4	926549.KI421517_gene109	1.872e-124	410.0	COG0477@1|root,COG2814@2|Bacteria,4NEQU@976|Bacteroidetes,47KKT@768503|Cytophagia	976|Bacteroidetes	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_6329391_7	1123248.KB893326_gene1428	6.832e-25	105.0	COG0236@1|root,COG0236@2|Bacteria,4NWTZ@976|Bacteroidetes	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH2_k127_6329391_3	1123248.KB893326_gene1429	1.411e-140	456.0	COG0508@1|root,COG0508@2|Bacteria,4NE41@976|Bacteroidetes,1IVKR@117747|Sphingobacteriia	976|Bacteroidetes	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_6329391_1	468059.AUHA01000003_gene1721	8.704e-164	520.0	COG0022@1|root,COG0022@2|Bacteria,4NFYK@976|Bacteroidetes,1IV1S@117747|Sphingobacteriia	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_6329391_2	1123057.P872_20460	9.41e-152	485.0	COG1071@1|root,COG1071@2|Bacteria,4NJMZ@976|Bacteroidetes,47U8U@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DTH2_k127_6329391_0	1123248.KB893326_gene1433	3.234e-285	883.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IWF1@117747|Sphingobacteriia	976|Bacteroidetes	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
DTH2_k127_635459_1	926562.Oweho_2692	2.92e-72	248.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,1HX7R@117743|Flavobacteriia,2PASN@246874|Cryomorphaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DTH2_k127_635459_2	1408473.JHXO01000005_gene1522	2.631e-51	190.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,2FN3J@200643|Bacteroidia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DTH2_k127_635459_0	1239962.C943_02403	7.012e-97	322.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JJV@768503|Cytophagia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH2_k127_6380703_1	85643.Tmz1t_2951	1.738e-125	413.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
DTH2_k127_6380703_0	85643.Tmz1t_2950	1.361e-187	595.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2W3EH@28216|Betaproteobacteria,2KZ1E@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
DTH2_k127_6380703_2	316055.RPE_0606	1.024e-15	82.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
DTH2_k127_6445002_0	1077285.AGDG01000016_gene539	4.077e-220	689.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,2FKYI@200643|Bacteroidia,4AKF0@815|Bacteroidaceae	976|Bacteroidetes	J	Psort location Cytoplasmic, score	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH2_k127_6445002_1	926562.Oweho_2205	1.518e-139	458.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia,2PAMH@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
DTH2_k127_6451599_3	926549.KI421517_gene408	1.999e-67	239.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_6451599_5	395492.Rleg2_1879	3.965e-09	63.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2UCXT@28211|Alphaproteobacteria,4BE8X@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
DTH2_k127_6451599_1	1237149.C900_03342	1.125e-121	397.0	COG0408@1|root,COG0408@2|Bacteria,4NFZS@976|Bacteroidetes,47M0F@768503|Cytophagia	976|Bacteroidetes	H	PFAM coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
DTH2_k127_6451599_0	1288963.ADIS_0527	9.252e-152	488.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH2_k127_6451599_2	1121129.KB903360_gene3482	3.7e-72	253.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,22XHA@171551|Porphyromonadaceae	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH2_k127_6451599_4	1454007.JAUG01000010_gene2554	9.849e-33	126.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_6470289_3	313606.M23134_01329	6.685e-57	203.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
DTH2_k127_6470289_4	1336803.PHEL49_0292	7.198e-19	88.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,1I3XI@117743|Flavobacteriia,3VWR2@52959|Polaribacter	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
DTH2_k127_6470289_0	485918.Cpin_4713	5.203e-159	509.0	COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia	976|Bacteroidetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DTH2_k127_6470289_1	1227739.Hsw_3790	7.261e-95	328.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia	976|Bacteroidetes	O	PFAM Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
DTH2_k127_6470289_2	1137281.D778_01922	1.158e-78	278.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,Inhibitor_I69,MAM,Peptidase_C10,Peptidase_M14,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,Reprolysin_4,fn3
DTH2_k127_6480142_4	1121898.Q766_02050	5.219e-152	484.0	COG2141@1|root,COG2141@2|Bacteria,4NHGI@976|Bacteroidetes,1HYI8@117743|Flavobacteriia,2NV2Z@237|Flavobacterium	976|Bacteroidetes	C	luciferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
DTH2_k127_6480142_1	1123278.KB893579_gene860	4.708e-210	665.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47MMB@768503|Cytophagia	976|Bacteroidetes	J	Amidase	gatA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
DTH2_k127_6480142_9	1144313.PMI10_03683	2.158e-37	146.0	COG0454@1|root,COG0456@2|Bacteria,4NVIN@976|Bacteroidetes,1I5VD@117743|Flavobacteriia,2NWND@237|Flavobacterium	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DTH2_k127_6480142_3	1341181.FLJC2902T_14610	9.906e-176	554.0	COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,1HZN9@117743|Flavobacteriia,2NV96@237|Flavobacterium	976|Bacteroidetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
DTH2_k127_6480142_5	1123248.KB893325_gene1168	3.437e-99	333.0	COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes,1J0CK@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_6480142_8	268407.PWYN_05655	7.947e-49	181.0	COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,26UA4@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase III subunit epsilon	polC_2	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T
DTH2_k127_6480142_0	1356852.N008_16255	6.224e-227	718.0	COG1164@1|root,COG1164@2|Bacteria,4NJFW@976|Bacteroidetes,47TFT@768503|Cytophagia	976|Bacteroidetes	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
DTH2_k127_6480142_6	1131812.JQMS01000001_gene2245	6.945e-72	250.0	COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,1HWW1@117743|Flavobacteriia,2NW7H@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the SOS response-associated peptidase family	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
DTH2_k127_6480142_2	1094466.KQS_00250	1.424e-182	580.0	COG0389@1|root,COG0389@2|Bacteria,4NGPH@976|Bacteroidetes,1HX7U@117743|Flavobacteriia,2NTED@237|Flavobacterium	976|Bacteroidetes	L	SOS mutagenesis and repair protein UmuC	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
DTH2_k127_6480142_7	1347342.BN863_25990	4.529e-59	208.0	COG1974@1|root,COG1974@2|Bacteria,4NQXK@976|Bacteroidetes,1I2WU@117743|Flavobacteriia	976|Bacteroidetes	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
DTH2_k127_6493504_4	1121946.AUAX01000002_gene344	1.934e-07	63.0	COG1404@1|root,COG2755@1|root,COG3209@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,2GK5H@201174|Actinobacteria,4D9TR@85008|Micromonosporales	201174|Actinobacteria	EGM	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,Ricin_B_lectin,VCBS
DTH2_k127_6493504_3	945713.IALB_1477	3.065e-13	81.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH2_k127_6493504_1	1121904.ARBP01000009_gene4229	4.668e-50	189.0	COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,47WA7@768503|Cytophagia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6493504_0	1408433.JHXV01000001_gene1029	2.599e-52	194.0	2BPRN@1|root,32IIX@2|Bacteria,4PEDZ@976|Bacteroidetes,1ICSQ@117743|Flavobacteriia,2PC0H@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6493504_2	1121870.AUAA01000002_gene2254	2.976e-19	94.0	COG4447@1|root,COG4447@2|Bacteria,4PM0K@976|Bacteroidetes,1I2DM@117743|Flavobacteriia,3HIMJ@358033|Chryseobacterium	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_6515264_3	926562.Oweho_2705	6.475e-45	166.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia,2PATM@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
DTH2_k127_6515264_1	1191523.MROS_1275	3.465e-301	937.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1275|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
DTH2_k127_6515264_0	1218108.KB908291_gene937	0.0	1050.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_6515264_2	755732.Fluta_1284	1.784e-56	214.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_6515264_4	1123278.KB893428_gene99	7.588e-30	128.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47KW1@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_8
DTH2_k127_6592712_4	762903.Pedsa_1419	1.895e-116	393.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6592712_2	1121904.ARBP01000001_gene5377	2.34e-162	523.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_6592712_7	742817.HMPREF9449_00183	8.957e-16	83.0	2CBZZ@1|root,32QA1@2|Bacteria,4NQPJ@976|Bacteroidetes,2FYEI@200643|Bacteroidia,230HI@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6592712_3	755732.Fluta_2750	4.789e-155	508.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1HYRP@117743|Flavobacteriia,2PBBJ@246874|Cryomorphaceae	976|Bacteroidetes	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
DTH2_k127_6592712_1	509635.N824_19040	1.29e-232	727.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DTH2_k127_6592712_0	1267211.KI669560_gene2005	1.21e-239	768.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1IVBF@117747|Sphingobacteriia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OMP_b-brl_3,Plug
DTH2_k127_6592712_8	670487.Ocepr_1362	0.0003365	45.0	2DRMQ@1|root,33CB6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6592712_5	1168034.FH5T_08455	1.171e-93	329.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,2FPZX@200643|Bacteroidia	976|Bacteroidetes	KT	PspC domain protein	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
DTH2_k127_6592712_6	1223410.KN050846_gene888	1.247e-45	167.0	COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,1I2SA@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
DTH2_k127_6616265_1	1121904.ARBP01000001_gene5937	1.046e-49	183.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_6616265_0	313606.M23134_04032	2.182e-145	469.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47JT9@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_6616265_2	755732.Fluta_3017	2.958e-11	64.0	COG0526@1|root,COG0607@1|root,COG0526@2|Bacteria,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia,2PC0A@246874|Cryomorphaceae	976|Bacteroidetes	COP	COGs COG0607 Rhodanese-related sulfurtransferase	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Thioredoxin
DTH2_k127_663595_3	742725.HMPREF9450_00695	9.243e-05	46.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,2FPYK@200643|Bacteroidia,22UD1@171550|Rikenellaceae	976|Bacteroidetes	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_663595_1	1150600.ADIARSV_1521	3.456e-159	512.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,1IPGA@117747|Sphingobacteriia	976|Bacteroidetes	K	ATPase (AAA	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
DTH2_k127_663595_0	743722.Sph21_0747	2.192e-199	631.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1IPSP@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_663595_2	1408433.JHXV01000006_gene2768	7.012e-53	192.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
DTH2_k127_6638392_2	926562.Oweho_1836	9.332e-102	339.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia,2PAFN@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_6638392_0	929556.Solca_4085	1.119e-199	632.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
DTH2_k127_6638392_1	485918.Cpin_1278	1.996e-110	362.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH2_k127_6638392_3	700598.Niako_3251	3.473e-48	185.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_6717315_5	1123276.KB893246_gene540	2.958e-11	64.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,47K0R@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_6717315_0	1453498.LG45_03450	1.244e-176	561.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia,2NU2U@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DTH2_k127_6717315_3	1296416.JACB01000032_gene2296	1.73e-56	200.0	COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,1I187@117743|Flavobacteriia,2YJFJ@290174|Aquimarina	976|Bacteroidetes	S	Fe-S metabolism associated domain	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
DTH2_k127_6717315_4	1121285.AUFK01000013_gene2413	1.504e-34	135.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,3ZS4E@59732|Chryseobacterium	976|Bacteroidetes	S	FeS assembly SUF system protein	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH2_k127_6717315_2	1454007.JAUG01000076_gene1350	7.878e-71	243.0	28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,1IS0K@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2480)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2480
DTH2_k127_6717315_1	880071.Fleli_0540	1.494e-91	303.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
DTH2_k127_6738550_1	1121957.ATVL01000006_gene2737	3.062e-184	608.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_6738550_3	1123277.KB893190_gene4924	1.541e-156	506.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
DTH2_k127_6738550_7	714943.Mucpa_3116	1.131e-63	224.0	COG0586@1|root,COG0586@2|Bacteria,4NMBP@976|Bacteroidetes,1IRXI@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH2_k127_6738550_5	1121957.ATVL01000010_gene506	1.54e-77	267.0	COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,47MMA@768503|Cytophagia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_6738550_10	153721.MYP_4034	1.414e-44	169.0	COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,47NTX@768503|Cytophagia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
DTH2_k127_6738550_9	929556.Solca_3745	1.974e-45	171.0	COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,1ITNF@117747|Sphingobacteriia	976|Bacteroidetes	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	-	-	-	-	-	-	-	-	-	ExbD
DTH2_k127_6738550_8	471854.Dfer_4058	2.416e-54	200.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHA@768503|Cytophagia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_6738550_11	485918.Cpin_1429	2.118e-31	134.0	COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,1ISCX@117747|Sphingobacteriia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_6738550_6	1227739.Hsw_0351	2.664e-72	256.0	COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,47NNB@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_6738550_4	153721.MYP_4029	3.329e-94	329.0	COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
DTH2_k127_6738550_0	1121899.Q764_09500	4.975e-267	837.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1HX75@117743|Flavobacteriia,2NTDV@237|Flavobacterium	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
DTH2_k127_6738550_2	926549.KI421517_gene1161	4.819e-172	571.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
DTH2_k127_6759155_2	1123057.P872_17695	6.179e-50	180.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
DTH2_k127_6759155_5	926562.Oweho_1648	4.358e-33	132.0	2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,1I425@117743|Flavobacteriia,2PB6J@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4286)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4286
DTH2_k127_6759155_0	1408473.JHXO01000011_gene2959	2.066e-94	316.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,2FMH1@200643|Bacteroidia	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DTH2_k127_6759155_3	1121481.AUAS01000008_gene3009	2.334e-43	168.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,47NDD@768503|Cytophagia	976|Bacteroidetes	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
DTH2_k127_6759155_4	886379.AEWI01000046_gene3109	4.427e-40	153.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia,3XK37@558415|Marinilabiliaceae	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
DTH2_k127_6759155_1	1235803.C825_04676	1.162e-65	230.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia,22XSI@171551|Porphyromonadaceae	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH2_k127_6759155_6	1307759.JOMJ01000003_gene1175	1.393e-23	103.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2WR93@28221|Deltaproteobacteria,2MDHT@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
DTH2_k127_6779976_5	1408433.JHXV01000001_gene669	1.939e-09	64.0	COG4733@1|root,COG4733@2|Bacteria,4PHUU@976|Bacteroidetes,1HZDA@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha integrin	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_6779976_2	1396858.Q666_08270	4.486e-22	99.0	COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,4698E@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
DTH2_k127_6779976_1	1313421.JHBV01000014_gene3914	7.722e-40	164.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_6779976_3	1296415.JACC01000038_gene1906	2.827e-15	76.0	2EMYX@1|root,33FM2@2|Bacteria,4NY90@976|Bacteroidetes,1IBIV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6779976_0	755732.Fluta_2892	3.324e-132	430.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	M60-like_N,PD40,Peptidase_M60
DTH2_k127_6779976_4	1185876.BN8_02298	9.326e-12	71.0	COG4319@1|root,COG4319@2|Bacteria,4NRVE@976|Bacteroidetes,47QDU@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_6809287_4	1296415.JACC01000001_gene3498	3.04e-09	61.0	COG0419@1|root,COG0419@2|Bacteria,4NGQP@976|Bacteroidetes,1HWVD@117743|Flavobacteriia,2YGWX@290174|Aquimarina	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6809287_1	153721.MYP_4062	5.692e-99	348.0	COG4733@1|root,COG4733@2|Bacteria,4NF53@976|Bacteroidetes,47MWJ@768503|Cytophagia	976|Bacteroidetes	S	SPTR Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6809287_0	1124780.ANNU01000042_gene619	7.364e-161	521.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH2_k127_6809287_2	700598.Niako_6385	1.136e-74	253.0	COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia	976|Bacteroidetes	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DTH2_k127_6809287_3	1313421.JHBV01000016_gene5527	4.146e-33	140.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1IWYM@117747|Sphingobacteriia	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
DTH2_k127_6832217_0	1121904.ARBP01000012_gene1190	2.823e-91	318.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_6832217_2	755732.Fluta_0111	1.828e-59	213.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1HXW4@117743|Flavobacteriia,2PAZY@246874|Cryomorphaceae	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH2_k127_6832217_1	485918.Cpin_2038	3.978e-61	214.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH2_k127_6845314_1	760192.Halhy_2333	1.082e-55	199.0	COG0477@1|root,COG2814@2|Bacteria,4NESW@976|Bacteroidetes,1IPF0@117747|Sphingobacteriia	976|Bacteroidetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08156	-	-	-	-	ko00000,ko02000	2.A.1.2.14	-	-	MFS_1,Sugar_tr
DTH2_k127_6845314_0	485918.Cpin_4445	1.472e-108	358.0	COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,1IPF1@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
DTH2_k127_6845314_4	1137281.D778_00773	2.848e-16	79.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,1I5MP@117743|Flavobacteriia	976|Bacteroidetes	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
DTH2_k127_6845314_3	762903.Pedsa_2371	2.936e-42	162.0	COG2353@1|root,COG2353@2|Bacteria,4NMFT@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_6845314_2	1191523.MROS_1351	2.004e-48	177.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	slyA	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
DTH2_k127_6845314_5	927658.AJUM01000047_gene2816	2.354e-05	48.0	2AD7J@1|root,312WH@2|Bacteria,4NR1A@976|Bacteroidetes,2G24U@200643|Bacteroidia,3XK3Q@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_6866292_1	643867.Ftrac_1723	1.332e-64	223.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia	976|Bacteroidetes	EF	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH2_k127_6866292_0	269798.CHU_2868	1.943e-93	318.0	COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
DTH2_k127_6866292_2	313606.M23134_00463	1.274e-47	177.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,4NIXZ@976|Bacteroidetes,47MCW@768503|Cytophagia	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,PAS,PAS_4,PAS_9,SpoIIE
DTH2_k127_6899507_1	1492738.FEM21_08080	1.488e-62	218.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,1HYNV@117743|Flavobacteriia,2NSH9@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
DTH2_k127_6899507_3	468059.AUHA01000003_gene1826	1.107e-47	182.0	28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6899507_2	1123037.AUDE01000032_gene2266	1.431e-53	190.0	COG1143@1|root,COG1143@2|Bacteria,4PKCQ@976|Bacteroidetes,1IJ7N@117743|Flavobacteriia	976|Bacteroidetes	C	ferredoxin	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
DTH2_k127_6899507_0	746697.Aeqsu_2780	2.445e-84	287.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia	976|Bacteroidetes	C	acyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH2_k127_6916560_4	153721.MYP_198	2.727e-13	83.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6916560_2	869213.JCM21142_31183	3.831e-73	253.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,47JCE@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_6916560_1	1150600.ADIARSV_1907	5.69e-95	324.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1IQGQ@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_6916560_0	525373.HMPREF0766_10214	9.277e-177	560.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1INNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DTH2_k127_6916560_3	760192.Halhy_2641	3.172e-27	115.0	COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6951906_3	755732.Fluta_0281	2.027e-43	172.0	2DKXU@1|root,30TFF@2|Bacteria,4NPBR@976|Bacteroidetes,1I8N7@117743|Flavobacteriia,2PAAX@246874|Cryomorphaceae	976|Bacteroidetes	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
DTH2_k127_6951906_1	1121957.ATVL01000011_gene3946	4.376e-155	502.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KDQ@768503|Cytophagia	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH2_k127_6951906_4	981085.XP_010090550.1	7.085e-07	62.0	COG2730@1|root,2QPYU@2759|Eukaryota,37J2V@33090|Viridiplantae,3GGVF@35493|Streptophyta,4JSS3@91835|fabids	35493|Streptophyta	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH2_k127_6951906_2	269798.CHU_0076	7.897e-90	318.0	COG1807@1|root,COG1807@2|Bacteria,4NP7Y@976|Bacteroidetes,47UYH@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6951906_0	929556.Solca_1210	1.535e-165	529.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,1IQEC@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DTH2_k127_6992272_1	1408433.JHXV01000024_gene1473	3.31e-158	506.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia,2PA9E@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM DegT DnrJ EryC1 StrS aminotransferase family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_6992272_0	1121904.ARBP01000003_gene6520	1.257e-219	687.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	tuaD	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH2_k127_6992272_2	908612.HMPREF9720_2267	8.649e-99	329.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,2FMQF@200643|Bacteroidia,22TZY@171550|Rikenellaceae	976|Bacteroidetes	L	EXOIII	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
DTH2_k127_6992272_3	929703.KE386491_gene805	5.729e-86	289.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,47MHB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DTH2_k127_6992272_4	762903.Pedsa_3566	8.162e-75	257.0	COG3132@1|root,COG3132@2|Bacteria,4NG7X@976|Bacteroidetes,1IRRC@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
DTH2_k127_6992272_5	1249480.B649_08375	7.094e-23	100.0	COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,42UBJ@68525|delta/epsilon subdivisions,2YP8N@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7039005_7	1168034.FH5T_12365	5.251e-33	133.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,2FMUQ@200643|Bacteroidia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
DTH2_k127_7039005_5	1408433.JHXV01000036_gene268	1.385e-44	173.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes,1IAKI@117743|Flavobacteriia,2PB7R@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7039005_0	1144313.PMI10_03276	7.569e-121	398.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,2NTTH@237|Flavobacterium	976|Bacteroidetes	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH2_k127_7039005_2	1408473.JHXO01000006_gene1059	5.234e-80	272.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,2FSTZ@200643|Bacteroidia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DTH2_k127_7039005_6	1313421.JHBV01000011_gene4054	1.247e-38	156.0	2D45Q@1|root,32TGB@2|Bacteria,4NTFZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7039005_4	1123277.KB893193_gene3868	6.844e-49	178.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47QSI@768503|Cytophagia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DTH2_k127_7039005_3	926562.Oweho_1656	3.923e-66	235.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1HYA2@117743|Flavobacteriia,2PB1H@246874|Cryomorphaceae	976|Bacteroidetes	EG	EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_7039005_1	929556.Solca_2588	5.699e-82	280.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1IQIP@117747|Sphingobacteriia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
DTH2_k127_7056407_2	497964.CfE428DRAFT_5016	0.0002771	51.0	2DXC9@1|root,344D3@2|Bacteria,46W86@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
DTH2_k127_7056407_1	714943.Mucpa_3542	1.488e-102	342.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,1IPHC@117747|Sphingobacteriia	976|Bacteroidetes	V	peptidase	ykfA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
DTH2_k127_7056407_0	468059.AUHA01000002_gene889	3.59e-161	511.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1IPA1@117747|Sphingobacteriia	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DTH2_k127_7178099_1	468059.AUHA01000002_gene936	6.216e-141	454.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH2_k127_7178099_0	755732.Fluta_3876	0.0	1050.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,1HX7T@117743|Flavobacteriia,2PAB2@246874|Cryomorphaceae	976|Bacteroidetes	G	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DTH2_k127_7178099_6	867900.Celly_1317	2.158e-32	129.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,1I2V4@117743|Flavobacteriia,1F9JX@104264|Cellulophaga	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
DTH2_k127_7178099_2	1122176.KB903535_gene1970	5.221e-71	258.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes	976|Bacteroidetes	E	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,MAM,TSP_3,fn3
DTH2_k127_7178099_4	1121373.KB903620_gene2240	8.732e-38	155.0	COG3064@1|root,COG3064@2|Bacteria,4NM6Q@976|Bacteroidetes,47P6I@768503|Cytophagia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_7178099_3	926549.KI421517_gene1509	5.876e-38	153.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4PKPC@976|Bacteroidetes,47N8S@768503|Cytophagia	976|Bacteroidetes	DZ	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,RCC1
DTH2_k127_7178099_7	1237149.C900_05112	8.334e-28	116.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia	976|Bacteroidetes	S	PFAM Membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DTH2_k127_7178099_9	1121287.AUMU01000001_gene1696	1.745e-08	64.0	2D7E4@1|root,32TNW@2|Bacteria,4NSYH@976|Bacteroidetes,1I4B8@117743|Flavobacteriia,3ZNI8@59732|Chryseobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476
DTH2_k127_7178099_5	1408433.JHXV01000017_gene1597	5.463e-35	143.0	2C52N@1|root,315JU@2|Bacteria,4PJRQ@976|Bacteroidetes,1IE9T@117743|Flavobacteriia,2PB34@246874|Cryomorphaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_7178099_8	1249997.JHZW01000003_gene3762	5.997e-13	70.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,1HX52@117743|Flavobacteriia,2PGRV@252356|Maribacter	976|Bacteroidetes	Q	Mycolic acid cyclopropane synthetase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DTH2_k127_7277160_6	671065.MetMK1DRAFT_00010080	1.586e-107	363.0	COG0550@1|root,arCOG01527@2157|Archaea,2XQ00@28889|Crenarchaeota	28889|Crenarchaeota	L	DNA topoisomerase, type IA, central domain protein	topA	-	5.99.1.2	ko:K03168,ko:K03169	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
DTH2_k127_7277160_4	1121373.KB903662_gene54	1.144e-156	503.0	COG2081@1|root,COG2081@2|Bacteria,4NFQ9@976|Bacteroidetes,47KHX@768503|Cytophagia	976|Bacteroidetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH2_k127_7277160_2	926549.KI421517_gene3609	5.964e-207	662.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
DTH2_k127_7277160_7	929556.Solca_2887	5.998e-67	233.0	COG1999@1|root,COG1999@2|Bacteria,4NN4N@976|Bacteroidetes,1IZ7Y@117747|Sphingobacteriia	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_7277160_5	929556.Solca_2886	2.343e-113	370.0	COG1262@1|root,COG1262@2|Bacteria,4NGBN@976|Bacteroidetes,1IUAX@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_7277160_1	929556.Solca_2885	2.597e-253	788.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,4NEXP@976|Bacteroidetes,1IQ7I@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	nirK	-	1.7.2.1	ko:K00368,ko:K00405	ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020	M00156,M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3
DTH2_k127_7277160_10	985255.APHJ01000018_gene2998	5.868e-31	126.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1I2ZX@117743|Flavobacteriia,2P7K7@244698|Gillisia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH2_k127_7277160_9	1123248.KB893337_gene2588	2.661e-35	139.0	COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,1ITI1@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
DTH2_k127_7277160_3	1124780.ANNU01000025_gene3363	1.536e-181	591.0	COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,47JK1@768503|Cytophagia	976|Bacteroidetes	L	PIF1-like helicase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_40,Herpes_Helicase,PIF1
DTH2_k127_7277160_8	1347342.BN863_2350	1.229e-57	206.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DTH2_k127_7277160_0	1408473.JHXO01000001_gene2295	0.0	1642.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
DTH2_k127_7278181_3	755732.Fluta_0829	8.577e-22	109.0	COG5305@1|root,COG5305@2|Bacteria,4PAK3@976|Bacteroidetes,1IMPV@117743|Flavobacteriia,2PAU3@246874|Cryomorphaceae	976|Bacteroidetes	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_7278181_0	1408473.JHXO01000013_gene557	2.849e-286	900.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,2G3H3@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_7278181_2	374847.Kcr_0638	8.832e-79	283.0	arCOG02559@1|root,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DTH2_k127_7278181_1	925409.KI911562_gene380	1.011e-111	393.0	COG1361@1|root,COG3209@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_7278181_6	1313421.JHBV01000024_gene4954	4.396e-05	57.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,SLH,SprB,VCBS
DTH2_k127_7278181_4	634994.GCWU000323_01831	2.913e-10	61.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7305708_1	1121899.Q764_06350	2.718e-70	243.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1I1F1@117743|Flavobacteriia,2NSSP@237|Flavobacterium	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_7305708_0	1408473.JHXO01000010_gene3689	6.814e-315	997.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
DTH2_k127_7305708_3	880071.Fleli_3075	1.418e-22	102.0	2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,47R7M@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1987
DTH2_k127_7305708_2	755732.Fluta_0605	2.381e-35	150.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2PAUX@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
DTH2_k127_7305708_4	1144275.COCOR_05233	2.895e-20	99.0	COG2849@1|root,COG2849@2|Bacteria,1NMUU@1224|Proteobacteria,432BU@68525|delta/epsilon subdivisions,2WT7D@28221|Deltaproteobacteria,2Z2M9@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_7346665_12	1408473.JHXO01000001_gene2233	7.431e-40	149.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,2FSH0@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
DTH2_k127_7346665_10	485918.Cpin_3687	6.331e-67	241.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_7346665_13	163908.KB235896_gene4774	9.122e-32	126.0	COG1324@1|root,COG1324@2|Bacteria,1G7PJ@1117|Cyanobacteria,1HP9B@1161|Nostocales	1117|Cyanobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DTH2_k127_7346665_7	929713.NIASO_15420	1.787e-85	289.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1IR1A@117747|Sphingobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
DTH2_k127_7346665_2	1279009.ADICEAN_02510	2.734e-116	388.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia	976|Bacteroidetes	CP	COGs COG1668 ABC-type Na efflux pump permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_7346665_8	926562.Oweho_3041	1.425e-83	288.0	COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,1IMPX@117743|Flavobacteriia,2PAVM@246874|Cryomorphaceae	976|Bacteroidetes	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
DTH2_k127_7346665_1	1168289.AJKI01000011_gene570	3.507e-177	563.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia,3XIRD@558415|Marinilabiliaceae	976|Bacteroidetes	T	Sigma-54 interaction domain	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_7346665_5	1168067.JAGP01000001_gene434	1.428e-99	339.0	COG0859@1|root,COG0859@2|Bacteria,1QRJF@1224|Proteobacteria,1RUK1@1236|Gammaproteobacteria,46258@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
DTH2_k127_7346665_11	1469557.JSWF01000026_gene3438	3.464e-51	190.0	COG1073@1|root,COG1073@2|Bacteria,4NQYV@976|Bacteroidetes,1I37B@117743|Flavobacteriia	976|Bacteroidetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
DTH2_k127_7346665_9	1121898.Q766_04475	2.967e-67	231.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1I1XN@117743|Flavobacteriia,2NW14@237|Flavobacterium	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
DTH2_k127_7346665_4	762903.Pedsa_3394	3.603e-110	364.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
DTH2_k127_7346665_3	926562.Oweho_2841	3.189e-114	376.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia,2PA55@246874|Cryomorphaceae	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_7346665_0	1267211.KI669560_gene1415	2.286e-231	720.0	COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DTH2_k127_7346665_15	929703.KE386491_gene2553	2.052e-13	77.0	2EE6M@1|root,33815@2|Bacteria,4NX3M@976|Bacteroidetes,47S10@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7346665_14	929562.Emtol_2833	1.879e-29	129.0	28JMY@1|root,2Z9ED@2|Bacteria,4NGSX@976|Bacteroidetes,47S1P@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	-
DTH2_k127_7346665_6	1408473.JHXO01000012_gene333	1.235e-94	313.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,2FQQ7@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.88,1.5.5.2	ko:K00128,ko:K13821	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00245,R00264,R00631,R00707,R00708,R00710,R00904,R01253,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04444,R04445,R04506,R04903,R05050,R05051,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00083,RC00186,RC00216,RC00218,RC00242,RC00255,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
DTH2_k127_7437919_2	1121373.KB903642_gene3696	3.29e-59	215.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7437919_3	761193.Runsl_5183	4.961e-40	154.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_7437919_4	313598.MED152_13344	1.564e-08	61.0	COG2010@1|root,COG2010@2|Bacteria,4NWPQ@976|Bacteroidetes,1IN2Q@117743|Flavobacteriia,3VWUB@52959|Polaribacter	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7437919_0	1249975.JQLP01000005_gene2704	6.532e-218	680.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia,2P655@244698|Gillisia	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, N-terminal domain	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_7437919_1	755732.Fluta_1284	6.22e-117	404.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_7475819_3	1313301.AUGC01000017_gene818	9.131e-07	57.0	2E691@1|root,330X3@2|Bacteria,4NVM3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7475819_0	926551.KB900703_gene1076	2.747e-104	349.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia,1EQAA@1016|Capnocytophaga	976|Bacteroidetes	IQ	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
DTH2_k127_7475819_2	1408473.JHXO01000006_gene1071	4.837e-80	281.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7475819_1	269798.CHU_0709	2.955e-82	293.0	COG4412@1|root,COG4412@2|Bacteria,4NF4S@976|Bacteroidetes,47R9E@768503|Cytophagia	976|Bacteroidetes	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7500198_2	1408433.JHXV01000014_gene3628	9.863e-125	419.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_7500198_3	983544.Lacal_0968	3.09e-67	234.0	COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,1HYXC@117743|Flavobacteriia	976|Bacteroidetes	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
DTH2_k127_7500198_0	391596.PBAL39_12007	0.0	1100.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DTH2_k127_7500198_4	869213.JCM21142_3966	1.933e-51	194.0	29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7500198_5	869213.JCM21142_3965	1.154e-20	98.0	2DXS6@1|root,34692@2|Bacteria,4P5EX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7500198_1	421072.IO89_12705	6.415e-160	514.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1HXRK@117743|Flavobacteriia,3HHD3@358033|Chryseobacterium	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
DTH2_k127_7511268_2	743722.Sph21_1321	2.25e-92	311.0	COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia	976|Bacteroidetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH2_k127_7511268_6	468059.AUHA01000003_gene1947	3.932e-31	126.0	COG0824@1|root,COG0824@2|Bacteria,4NQ3I@976|Bacteroidetes,1ITE5@117747|Sphingobacteriia	976|Bacteroidetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_7511268_0	1121129.KB903359_gene2189	8.518e-199	637.0	COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,2FMAA@200643|Bacteroidia,22WNH@171551|Porphyromonadaceae	976|Bacteroidetes	GM	Polysaccharide biosynthesis protein	cap5D	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
DTH2_k127_7511268_1	1538644.KO02_01025	1.556e-173	550.0	COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,1IPCZ@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DTH2_k127_7511268_4	755732.Fluta_2607	2.142e-83	282.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IMQY@117743|Flavobacteriia,2PBHE@246874|Cryomorphaceae	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
DTH2_k127_7511268_3	869213.JCM21142_93584	4.391e-88	293.0	COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes	976|Bacteroidetes	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DTH2_k127_7511268_5	1185876.BN8_03804	8.912e-73	254.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,47MXY@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
DTH2_k127_7594098_1	927658.AJUM01000011_gene1314	6.141e-129	415.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,3XJNQ@558415|Marinilabiliaceae	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_7594098_0	485917.Phep_1479	2.665e-130	421.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1IR6K@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH2_k127_7594098_4	1168034.FH5T_13680	9.848e-60	221.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7594098_3	1121904.ARBP01000007_gene2907	2.049e-109	364.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
DTH2_k127_7594098_2	1168034.FH5T_13670	4.365e-111	368.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia	976|Bacteroidetes	S	Von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
DTH2_k127_7606889_2	515635.Dtur_1286	5.005e-36	155.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
DTH2_k127_7606889_0	1121957.ATVL01000012_gene817	1.623e-99	343.0	COG1404@1|root,COG3291@1|root,COG4733@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NHDH@976|Bacteroidetes,47YQJ@768503|Cytophagia	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M9,Peptidase_M9_N
DTH2_k127_7606889_1	1227739.Hsw_2817	6.435e-59	223.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47RJR@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_7640501_5	1168289.AJKI01000016_gene1962	1.699e-58	211.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,2FPFT@200643|Bacteroidia,3XJNF@558415|Marinilabiliaceae	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
DTH2_k127_7640501_8	743722.Sph21_0329	1.752e-48	176.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1ITFK@117747|Sphingobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
DTH2_k127_7640501_1	1249975.JQLP01000001_gene3197	8.515e-141	453.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,1HYS3@117743|Flavobacteriia,2P6GN@244698|Gillisia	976|Bacteroidetes	E	Semialdehyde dehydrogenase, NAD binding domain	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH2_k127_7640501_7	1408433.JHXV01000015_gene1717	1.502e-51	188.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I28F@117743|Flavobacteriia,2PAZ5@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_7640501_9	1120965.AUBV01000014_gene1168	2.166e-20	104.0	COG3291@1|root,COG3291@2|Bacteria,4NNVK@976|Bacteroidetes,47XA2@768503|Cytophagia	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_7640501_10	1408433.JHXV01000010_gene584	2.747e-20	98.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1I1A4@117743|Flavobacteriia,2PBNV@246874|Cryomorphaceae	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_7640501_0	1408473.JHXO01000001_gene2084	6.404e-240	755.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,2FNW9@200643|Bacteroidia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DTH2_k127_7640501_6	869213.JCM21142_52127	9.021e-58	213.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes	976|Bacteroidetes	S	gliding motility	gldN	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7640501_3	1150600.ADIARSV_4233	1.308e-77	280.0	COG4219@1|root,COG4219@2|Bacteria,4PKZS@976|Bacteroidetes,1IR4A@117747|Sphingobacteriia	976|Bacteroidetes	KT	Gliding motility-associated protein GldM	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
DTH2_k127_7640501_4	1124780.ANNU01000006_gene2937	6.955e-59	214.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,47MA3@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated protein GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7640501_2	1408433.JHXV01000024_gene1506	5.179e-113	371.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,1HXXN@117743|Flavobacteriia,2PAKH@246874|Cryomorphaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_769333_0	266748.HY04_13600	1.136e-133	436.0	COG3104@1|root,COG3104@2|Bacteria,4NGWH@976|Bacteroidetes,1HY6B@117743|Flavobacteriia,3ZNTZ@59732|Chryseobacterium	976|Bacteroidetes	E	Amino acid transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH2_k127_769333_2	1168034.FH5T_17555	4.047e-94	317.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,2FP92@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
DTH2_k127_769333_1	1250006.JHZZ01000001_gene2497	7.499e-95	318.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia,3VV30@52959|Polaribacter	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DTH2_k127_770920_1	925409.KI911562_gene2570	2.066e-108	355.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DTH2_k127_770920_0	926562.Oweho_3367	3.143e-166	539.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia,2PAGK@246874|Cryomorphaceae	976|Bacteroidetes	L	PFAM DNA gyrase topoisomerase IV, subunit A	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH2_k127_7784370_0	485918.Cpin_1974	4.902e-278	859.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,1IQCA@117747|Sphingobacteriia	976|Bacteroidetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_7784370_1	1444711.CCJF01000005_gene174	3.492e-174	550.0	COG0208@1|root,COG0208@2|Bacteria,2JGN2@204428|Chlamydiae	204428|Chlamydiae	F	Ribonucleotide reductase, small chain	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
DTH2_k127_7784370_2	1270196.JCKI01000009_gene3248	5.645e-116	384.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
DTH2_k127_7784370_3	1237149.C900_02393	1.536e-07	53.0	2AFYA@1|root,31622@2|Bacteria,4P4XX@976|Bacteroidetes,47VB7@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1571)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571,LysM
DTH2_k127_7809795_1	1313301.AUGC01000006_gene34	1.193e-89	318.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4P04N@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_7809795_0	313606.M23134_00084	8.393e-121	392.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,47KGP@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
DTH2_k127_7853699_2	1408433.JHXV01000005_gene2313	1.192e-138	443.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,1HWWI@117743|Flavobacteriia,2PACZ@246874|Cryomorphaceae	976|Bacteroidetes	G	Transketolase, pyrimidine binding domain	dxs	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_7853699_3	153721.MYP_3100	4.31e-100	354.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,4P298@976|Bacteroidetes,47TIX@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,TPR_19
DTH2_k127_7853699_1	1380600.AUYN01000009_gene1643	5.675e-145	471.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,1HWMY@117743|Flavobacteriia	976|Bacteroidetes	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
DTH2_k127_7853699_0	929556.Solca_0293	2.634e-192	621.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7853699_4	1408813.AYMG01000028_gene2517	2.18e-44	162.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1IPN9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_7883538_1	926562.Oweho_0392	4.121e-20	104.0	2BJHF@1|root,32DUB@2|Bacteria,4P9RZ@976|Bacteroidetes,1ICNC@117743|Flavobacteriia,2PB7V@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7883538_0	317936.Nos7107_5206	4.687e-23	111.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DTH2_k127_7887272_0	153721.MYP_2228	7.011e-284	900.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_7887272_1	945713.IALB_0609	8.524e-126	426.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	PD40,Peptidase_S9
DTH2_k127_7891057_2	517418.Ctha_2624	7.763e-62	220.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
DTH2_k127_7891057_0	153721.MYP_315	1.038e-70	246.0	28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7891057_1	926549.KI421517_gene38	5.094e-64	232.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,47NTZ@768503|Cytophagia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
DTH2_k127_7929397_3	1408433.JHXV01000038_gene2198	1.239e-86	311.0	COG2885@1|root,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_7929397_4	926562.Oweho_3393	4.171e-70	241.0	COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia,2PATQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
DTH2_k127_7929397_0	1408433.JHXV01000044_gene3184	8.256e-160	532.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
DTH2_k127_7929397_5	1408433.JHXV01000044_gene3183	1.837e-51	191.0	COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,1ICQF@117743|Flavobacteriia,2PBRF@246874|Cryomorphaceae	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
DTH2_k127_7929397_1	1408433.JHXV01000044_gene3182	1.82e-125	412.0	COG0438@1|root,COG0438@2|Bacteria,4PI5K@976|Bacteroidetes,1IGDT@117743|Flavobacteriia,2PB9M@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_7929397_2	1123057.P872_00825	1.907e-119	393.0	COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,47NAK@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM ribosomal RNA small subunit methyltransferase RsmB	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
DTH2_k127_7930236_4	929556.Solca_4246	3.049e-41	156.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
DTH2_k127_7930236_1	755732.Fluta_3660	1.537e-100	333.0	COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IMQP@117743|Flavobacteriia,2PBFH@246874|Cryomorphaceae	976|Bacteroidetes	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
DTH2_k127_7930236_5	926549.KI421517_gene1987	4.827e-33	130.0	COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia	976|Bacteroidetes	H	MoeZ MoeB domain	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
DTH2_k127_7930236_3	755732.Fluta_0193	5.509e-74	254.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,1IISJ@117743|Flavobacteriia	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH2_k127_7930236_2	468059.AUHA01000002_gene556	1.141e-90	304.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
DTH2_k127_7930236_0	1317122.ATO12_05990	1.384e-302	940.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,1HXV3@117743|Flavobacteriia,2YIV2@290174|Aquimarina	976|Bacteroidetes	L	Ultra-violet resistance protein B	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DTH2_k127_7930236_6	1453500.AT05_10875	0.0001223	53.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZEJ@117743|Flavobacteriia	976|Bacteroidetes	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH2_k127_7937949_0	1313421.JHBV01000041_gene3497	1.125e-88	298.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH2_k127_7937949_2	926551.KB900704_gene865	1.584e-42	158.0	COG2852@1|root,COG2852@2|Bacteria,4NQRT@976|Bacteroidetes,1I3MY@117743|Flavobacteriia,1ES7G@1016|Capnocytophaga	976|Bacteroidetes	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
DTH2_k127_7937949_1	1047013.AQSP01000144_gene895	1.807e-66	233.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH2_k127_7947611_3	459349.CLOAM0656	3.359e-33	130.0	COG1208@1|root,COG1208@2|Bacteria,2NPHW@2323|unclassified Bacteria	2|Bacteria	JM	Nucleotidyl transferase	mpg2	-	2.7.7.13	ko:K00966,ko:K21210	ko00051,ko00520,ko01059,ko01100,ko01110,ko01130,map00051,map00520,map01059,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R11429	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_7947611_1	858215.Thexy_1881	4.363e-137	443.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,42F50@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.2.1.45,4.2.1.46	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R02426,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_7947611_0	1408473.JHXO01000010_gene3757	5.294e-154	497.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,2FS76@200643|Bacteroidia	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DTH2_k127_7947611_2	1121481.AUAS01000001_gene4814	2.787e-101	346.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,47ME6@768503|Cytophagia	976|Bacteroidetes	S	PFAM Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH2_k127_7978308_2	1408813.AYMG01000010_gene647	4.785e-34	136.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1IT0W@117747|Sphingobacteriia	976|Bacteroidetes	L	Helix-hairpin-helix motif	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
DTH2_k127_7978308_1	1346330.M472_21215	1.048e-65	229.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1IS3F@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
DTH2_k127_7978308_0	714943.Mucpa_4341	3.954e-192	606.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1IP19@117747|Sphingobacteriia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_7978308_3	153721.MYP_3590	1.603e-06	57.0	COG0401@1|root,COG0401@2|Bacteria,4PPYU@976|Bacteroidetes,47T42@768503|Cytophagia	976|Bacteroidetes	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
DTH2_k127_804888_3	1519464.HY22_06390	3.299e-49	180.0	COG0859@1|root,COG0859@2|Bacteria,1FF11@1090|Chlorobi	1090|Chlorobi	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH2_k127_804888_2	880071.Fleli_2399	1.748e-122	403.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,47PDJ@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_804888_4	926562.Oweho_0135	1.183e-29	131.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia,2PB39@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_804888_0	743722.Sph21_3175	3.79e-163	520.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1IR3X@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DTH2_k127_804888_5	313606.M23134_01212	1.415e-27	121.0	298K1@1|root,2ZVQX@2|Bacteria,4NNNX@976|Bacteroidetes,47Q8A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_804888_1	700598.Niako_5045	2.212e-123	416.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1IVJP@117747|Sphingobacteriia	976|Bacteroidetes	O	S53, subtilisin kexin sedolisin	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_804888_6	929556.Solca_4083	1.252e-12	69.0	COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
DTH2_k127_8052809_6	1250006.JHZZ01000001_gene1113	1.724e-08	59.0	COG4447@1|root,COG5520@1|root,COG4447@2|Bacteria,COG5520@2|Bacteria,4NKN9@976|Bacteroidetes,1I99B@117743|Flavobacteriia	976|Bacteroidetes	M	O-Glycosyl hydrolase family 30	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydr_30_2
DTH2_k127_8052809_1	153721.MYP_1744	2.632e-119	399.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8
DTH2_k127_8052809_0	755732.Fluta_1892	3.998e-227	744.0	COG1520@1|root,COG2312@1|root,COG4386@1|root,COG1520@2|Bacteria,COG2312@2|Bacteria,COG4386@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
DTH2_k127_8052809_2	485918.Cpin_2962	5.309e-38	166.0	COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,4NRDH@976|Bacteroidetes,1IWXM@117747|Sphingobacteriia	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8052809_4	1123248.KB893315_gene3013	3.745e-34	144.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1J0PK@117747|Sphingobacteriia	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8052809_3	1131269.AQVV01000004_gene642	2.445e-36	152.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH2_k127_8052809_5	945713.IALB_0702	2.131e-15	88.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_M6
DTH2_k127_8052809_7	1408433.JHXV01000001_gene833	1.638e-06	59.0	2A92F@1|root,30Y6G@2|Bacteria,4PBXE@976|Bacteroidetes,1IMRH@117743|Flavobacteriia,2PBQ0@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8055442_0	1121904.ARBP01000002_gene7294	0.0	1246.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47NQV@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_8055442_1	1443665.JACA01000001_gene2620	7.806e-99	338.0	COG3203@1|root,COG3203@2|Bacteria,4NDYW@976|Bacteroidetes,1HWYP@117743|Flavobacteriia,2YHEN@290174|Aquimarina	976|Bacteroidetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
DTH2_k127_8055442_2	313606.M23134_03349	2.642e-38	148.0	COG0526@1|root,COG0526@2|Bacteria,4NM4Y@976|Bacteroidetes,47PPH@768503|Cytophagia	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
DTH2_k127_8130340_0	1048983.EL17_01275	6.335e-136	443.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_8130340_2	1353276.JADR01000001_gene722	4.765e-06	61.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1HX7G@117743|Flavobacteriia	976|Bacteroidetes	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH2_k127_8130340_1	525373.HMPREF0766_10672	2.865e-12	81.0	28JMZ@1|root,2Z9EE@2|Bacteria,4NKS8@976|Bacteroidetes,1ISZ3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_820838_2	762903.Pedsa_2881	5.507e-70	250.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1J0Y6@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_820838_0	1408433.JHXV01000028_gene2123	2.933e-119	387.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,1HY7R@117743|Flavobacteriia,2PAT4@246874|Cryomorphaceae	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DTH2_k127_820838_1	153721.MYP_1661	1.698e-100	339.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,47NYD@768503|Cytophagia	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_8213259_2	1168289.AJKI01000031_gene1031	1.365e-32	131.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,2FMII@200643|Bacteroidia,3XJVU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
DTH2_k127_8213259_1	391612.CY0110_22007	1.099e-32	138.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,3KFNC@43988|Cyanothece	1117|Cyanobacteria	S	Leucine-rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
DTH2_k127_8213259_0	620914.JH621249_gene3368	5.219e-56	221.0	COG0419@1|root,COG0419@2|Bacteria,4NEZ2@976|Bacteroidetes,1HXTM@117743|Flavobacteriia	976|Bacteroidetes	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	MukB
DTH2_k127_8226396_2	1120951.AUBG01000002_gene1435	5.94e-21	95.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1HZSH@117743|Flavobacteriia	976|Bacteroidetes	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_8226396_1	927658.AJUM01000037_gene2191	1.139e-68	242.0	29UMW@1|root,30FZE@2|Bacteria,4NP3W@976|Bacteroidetes,2G24N@200643|Bacteroidia,3XJR5@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8226396_0	421072.IO89_05260	7.426e-142	459.0	COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,1HXCF@117743|Flavobacteriia,3HHAP@358033|Chryseobacterium	976|Bacteroidetes	I	Ketopantoate reductase PanE/ApbA	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DTH2_k127_8267187_0	1122179.KB890435_gene931	1.222e-98	329.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH2_k127_8267187_2	1453500.AT05_00860	5.601e-23	110.0	COG1449@1|root,COG3867@1|root,COG1449@2|Bacteria,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C,Glyco_hydro_53,Glyco_hydro_57,He_PIG,RicinB_lectin_2,SLH
DTH2_k127_8267187_1	391598.FBBAL38_09852	2.001e-93	327.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
DTH2_k127_831304_5	153721.MYP_1295	9.763e-46	173.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47NKW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_831304_1	1408433.JHXV01000001_gene703	1.241e-93	321.0	COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PC5X@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase family 4	mraY2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
DTH2_k127_831304_0	485918.Cpin_1092	6.644e-102	350.0	2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,1IQA3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_831304_2	1189612.A33Q_4461	1.436e-80	278.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DTH2_k127_831304_4	880071.Fleli_1328	9.304e-48	177.0	COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,47NS2@768503|Cytophagia	976|Bacteroidetes	C	PFAM cytochrome c oxidase subunit III	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_831304_3	926562.Oweho_1905	3.659e-76	261.0	COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia,2PAN3@246874|Cryomorphaceae	976|Bacteroidetes	C	Heme copper-type cytochrome quinol oxidase subunit 3	coxP	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_8382456_2	929556.Solca_2111	8.578e-93	308.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1IP4J@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DTH2_k127_8382456_1	694427.Palpr_2886	3.941e-153	505.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia,22WA9@171551|Porphyromonadaceae	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
DTH2_k127_8382456_3	1313421.JHBV01000016_gene5527	4.637e-48	194.0	COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1IWYM@117747|Sphingobacteriia	976|Bacteroidetes	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
DTH2_k127_8382456_0	929556.Solca_2077	0.0	1146.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,1INPU@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH2_k127_8382456_4	595460.RRSWK_01389	6.026e-14	75.0	COG0614@1|root,COG0614@2|Bacteria,2J0J0@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_8415985_0	926562.Oweho_0714	9.263e-254	795.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia,2PAJ7@246874|Cryomorphaceae	976|Bacteroidetes	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH2_k127_8415985_1	391596.PBAL39_20620	3.127e-41	162.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1ISAH@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
DTH2_k127_8415985_2	1121904.ARBP01000001_gene5875	1.029e-36	139.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
DTH2_k127_8439_4	1211813.CAPH01000018_gene1013	1.312e-10	62.0	COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,2G38E@200643|Bacteroidia	976|Bacteroidetes	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
DTH2_k127_8439_1	984262.SGRA_1737	1.249e-64	246.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_8439_6	1337936.IJ00_01500	9.83e-07	56.0	COG1246@1|root,COG1246@2|Bacteria,1G5ND@1117|Cyanobacteria,1HNCP@1161|Nostocales	1117|Cyanobacteria	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DTH2_k127_8439_0	1313421.JHBV01000030_gene2179	3.963e-112	381.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
DTH2_k127_8439_5	1089547.KB913013_gene3474	1.141e-07	58.0	2DQFZ@1|root,336KY@2|Bacteria,4NVIZ@976|Bacteroidetes,47SK8@768503|Cytophagia	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
DTH2_k127_8439_2	927658.AJUM01000037_gene2028	3.584e-32	130.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH2_k127_8439_3	411477.PARMER_02961	2.039e-20	102.0	COG4372@1|root,COG4372@2|Bacteria,4PKE4@976|Bacteroidetes,2FPKQ@200643|Bacteroidia,22W9H@171551|Porphyromonadaceae	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8439_7	888059.HMPREF9071_0639	0.0001109	47.0	COG0515@1|root,COG0515@2|Bacteria,4NJH8@976|Bacteroidetes,1I4US@117743|Flavobacteriia,1ER42@1016|Capnocytophaga	976|Bacteroidetes	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_8466754_0	700598.Niako_0758	2.33e-142	464.0	COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQCN@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8466754_1	1469557.JSWF01000045_gene471	1.034e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_8466754_2	869213.JCM21142_31111	7.524e-55	201.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,47JX1@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_8474700_3	925409.KI911562_gene886	6.793e-105	346.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1IQ9A@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
DTH2_k127_8474700_6	1123053.AUDG01000094_gene1805	2.058e-06	59.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	pip	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Peptidase_S9
DTH2_k127_8474700_4	1034807.FBFL15_0569	1.429e-15	81.0	296ZH@1|root,2ZU82@2|Bacteria,4P9C3@976|Bacteroidetes,1INDU@117743|Flavobacteriia,2NZ7P@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8474700_2	643867.Ftrac_0064	1.831e-138	448.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,47KPU@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_8474700_1	929556.Solca_4218	4.002e-148	475.0	COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DTH2_k127_8474700_0	1189612.A33Q_3120	7.271e-151	488.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_8474700_5	176946.XP_007430065.1	2.81e-15	87.0	COG4886@1|root,KOG0619@2759|Eukaryota,38BF2@33154|Opisthokonta,3BI2X@33208|Metazoa,3D20I@33213|Bilateria,48AET@7711|Chordata,48W86@7742|Vertebrata	33208|Metazoa	S	Leucine rich repeat containing 69	LRRC69	-	-	-	-	-	-	-	-	-	-	-	LRR_1,LRR_8
DTH2_k127_8481845_11	234267.Acid_1844	4.44e-34	134.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DTH2_k127_8481845_4	1408473.JHXO01000001_gene1945	1.866e-121	400.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,2FNG4@200643|Bacteroidia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_8481845_14	1124780.ANNU01000019_gene1796	0.0009424	46.0	COG0708@1|root,COG3291@1|root,COG0708@2|Bacteria,COG3291@2|Bacteria,4NM12@976|Bacteroidetes	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_8481845_3	153721.MYP_3727	3.888e-123	401.0	COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,47JX5@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	ykuF	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
DTH2_k127_8481845_0	153721.MYP_2617	6.659e-233	742.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
DTH2_k127_8481845_13	746697.Aeqsu_0758	1.34e-06	57.0	2EJP5@1|root,33DDZ@2|Bacteria,4PGDT@976|Bacteroidetes,1IA34@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8481845_8	1168034.FH5T_16685	5.363e-56	203.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,2FMIT@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_8481845_12	1453500.AT05_08815	3.24e-22	108.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DTH2_k127_8481845_2	1408433.JHXV01000001_gene1050	5.289e-147	473.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1HX2U@117743|Flavobacteriia,2PAHJ@246874|Cryomorphaceae	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DTH2_k127_8481845_10	373903.Hore_02770	7.633e-41	164.0	COG1266@1|root,COG1266@2|Bacteria,1UYGJ@1239|Firmicutes,24CIZ@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DTH2_k127_8481845_9	926562.Oweho_1584	4.367e-41	165.0	2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH2_k127_8481845_1	468059.AUHA01000002_gene32	7.753e-149	490.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DTH2_k127_8481845_5	926562.Oweho_1586	3.037e-91	306.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia,2PAR7@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH2_k127_8481845_7	411154.GFO_2057	6.985e-61	215.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
DTH2_k127_8481845_6	880070.Cycma_2006	9.96e-73	248.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DTH2_k127_8522375_3	1150600.ADIARSV_2087	3.045e-31	123.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1IQ2H@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH2_k127_8522375_0	929703.KE386491_gene310	1.156e-171	546.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,47JQP@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_8522375_1	929556.Solca_3552	6.754e-150	479.0	COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1IPHE@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH2_k127_8522375_2	1267211.KI669560_gene80	2.096e-122	397.0	COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
DTH2_k127_8527232_0	402612.FP0217	7.795e-252	791.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,1HX3Y@117743|Flavobacteriia,2NUC3@237|Flavobacterium	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DTH2_k127_8527232_3	755732.Fluta_1722	1.615e-43	169.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia,2PAZZ@246874|Cryomorphaceae	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
DTH2_k127_8527232_2	869213.JCM21142_1647	3.707e-64	226.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia	976|Bacteroidetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
DTH2_k127_8527232_1	1178825.ALIH01000003_gene2169	2.965e-71	246.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,1HXD6@117743|Flavobacteriia	976|Bacteroidetes	L	double-stranded RNA RNA-DNA hybrid binding protein	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
DTH2_k127_8547143_2	1121904.ARBP01000036_gene2102	3.436e-23	104.0	COG1404@1|root,COG1404@2|Bacteria,4NRWQ@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8547143_1	1288963.ADIS_0512	4.542e-33	141.0	2E0EQ@1|root,32W15@2|Bacteria,4NTKT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8547143_0	762903.Pedsa_3291	3.695e-258	800.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1IPCY@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DTH2_k127_8549582_1	926549.KI421517_gene3433	9.992e-160	510.0	COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47N3X@768503|Cytophagia	976|Bacteroidetes	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
DTH2_k127_8549582_2	1121481.AUAS01000006_gene756	4.81e-69	241.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DTH2_k127_8549582_0	865937.Gilli_0045	1.012e-240	769.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia,2P5WQ@244698|Gillisia	976|Bacteroidetes	L	helicase superfamily c-terminal domain	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DTH2_k127_8549582_3	613026.HRAG_00328	1.2e-67	239.0	COG2849@1|root,COG2849@2|Bacteria,1MZCG@1224|Proteobacteria,42XCP@68525|delta/epsilon subdivisions,2YQ7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_8565526_5	153721.MYP_2753	1.177e-58	211.0	COG2197@1|root,COG2197@2|Bacteria,4NNE9@976|Bacteroidetes,47QWZ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,Response_reg
DTH2_k127_8565526_4	1121373.KB903654_gene1522	5.5e-110	365.0	COG1670@1|root,COG1670@2|Bacteria,4NQ6A@976|Bacteroidetes,47QQA@768503|Cytophagia	976|Bacteroidetes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_8565526_0	929556.Solca_1191	3.438e-246	777.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
DTH2_k127_8565526_2	926562.Oweho_3340	7.806e-139	454.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Sulfatase
DTH2_k127_8565526_1	468059.AUHA01000004_gene2341	1.031e-216	682.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1IQ95@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase, family M20 M25 M40	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_8565526_3	945713.IALB_3004	2.203e-116	383.0	COG0276@1|root,COG0276@2|Bacteria	2|Bacteria	H	ferrochelatase activity	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
DTH2_k127_8565526_11	762903.Pedsa_1821	3.039e-21	108.0	COG2353@1|root,COG2353@2|Bacteria,4PP3D@976|Bacteroidetes	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8565526_6	1144313.PMI10_00607	2.12e-57	209.0	COG0147@1|root,COG0147@2|Bacteria,4NECR@976|Bacteroidetes,1HY8U@117743|Flavobacteriia,2NU0V@237|Flavobacterium	976|Bacteroidetes	EH	Aminobenzoate synthetase	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH2_k127_8591730_6	1250232.JQNJ01000001_gene1027	3.598e-30	125.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DTH2_k127_8591730_3	1185876.BN8_05789	7.59e-89	300.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,47JPF@768503|Cytophagia	976|Bacteroidetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
DTH2_k127_8591730_0	1116472.MGMO_109c00050	6.545e-158	507.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XE5B@135618|Methylococcales	1236|Gammaproteobacteria	E	PFAM Aminotransferase, class I	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_8591730_5	1048983.EL17_11580	5.148e-42	160.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DTH2_k127_8591730_2	153721.MYP_2527	1.667e-105	367.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
DTH2_k127_8591730_1	485918.Cpin_6534	5.517e-131	422.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
DTH2_k127_8591730_4	485918.Cpin_6535	7.822e-76	256.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,1IQ4F@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_8606245_6	694427.Palpr_2227	0.0008835	45.0	COG5279@1|root,COG5279@2|Bacteria,4NRMB@976|Bacteroidetes,2FSFP@200643|Bacteroidia	976|Bacteroidetes	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH2_k127_8606245_2	485918.Cpin_5452	1.949e-113	369.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1IPJX@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
DTH2_k127_8606245_0	1086011.HJ01_02906	4.182e-162	521.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,1HXEF@117743|Flavobacteriia,2NTHJ@237|Flavobacterium	976|Bacteroidetes	S	MFS transporter permease	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
DTH2_k127_8606245_4	1453498.LG45_13700	1.591e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,2NTU8@237|Flavobacterium	976|Bacteroidetes	T	ArsR family transcriptional regulator	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_8606245_5	153721.MYP_93	4.61e-27	114.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia	976|Bacteroidetes	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_8606245_1	927658.AJUM01000037_gene2071	7.745e-118	392.0	COG3746@1|root,COG3746@2|Bacteria,4NIRE@976|Bacteroidetes,2FR58@200643|Bacteroidia	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH2_k127_8606245_3	36875.HQ29_04265	5.558e-97	323.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,2FMW1@200643|Bacteroidia,22X86@171551|Porphyromonadaceae	976|Bacteroidetes	P	Bacterial extracellular solute-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_8641388_2	883096.HMPREF9699_01007	4.316e-46	179.0	COG0582@1|root,COG0582@2|Bacteria,4PKC8@976|Bacteroidetes,1HYZC@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase
DTH2_k127_8641388_7	1121481.AUAS01000040_gene5312	1.958e-12	72.0	COG0789@1|root,COG0789@2|Bacteria,4PNWJ@976|Bacteroidetes,47YI1@768503|Cytophagia	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
DTH2_k127_8641388_6	1237149.C900_02304	2.077e-22	112.0	COG1066@1|root,COG1066@2|Bacteria,4P216@976|Bacteroidetes,47THX@768503|Cytophagia	976|Bacteroidetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
DTH2_k127_8641388_4	323261.Noc_0638	1.871e-40	152.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,1WZ7V@135613|Chromatiales	135613|Chromatiales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
DTH2_k127_8641388_3	865938.Weevi_1959	5.216e-46	174.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,4NIBY@976|Bacteroidetes,1HY8E@117743|Flavobacteriia	976|Bacteroidetes	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
DTH2_k127_8641388_5	1120965.AUBV01000004_gene1041	1.036e-30	123.0	COG2963@1|root,COG2963@2|Bacteria,4NZPP@976|Bacteroidetes	976|Bacteroidetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
DTH2_k127_8641388_9	1121287.AUMU01000008_gene2086	0.0007824	51.0	COG2831@1|root,COG2831@2|Bacteria,4PN2P@976|Bacteroidetes,1IK44@117743|Flavobacteriia,3ZRH4@59732|Chryseobacterium	976|Bacteroidetes	U	Mycoplasma protein of unknown function, DUF285	-	-	-	-	-	-	-	-	-	-	-	-	DUF285
DTH2_k127_8641388_0	1121957.ATVL01000014_gene1459	9.395e-86	299.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8641388_8	1453500.AT05_04560	8.753e-07	61.0	COG2374@1|root,COG3291@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD,PKD,fn3
DTH2_k127_8641388_1	700598.Niako_3251	3.374e-78	274.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_8652524_15	1313301.AUGC01000008_gene484	2.32e-07	53.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes	976|Bacteroidetes	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_8652524_10	927658.AJUM01000037_gene2319	1.751e-24	109.0	COG3449@1|root,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,GyrI-like,SOUL
DTH2_k127_8652524_11	153721.MYP_3896	1.558e-16	85.0	2CBAQ@1|root,30Y66@2|Bacteria,4PBX7@976|Bacteroidetes,47WGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8652524_12	1279009.ADICEAN_02013	1.861e-14	78.0	2D4Y8@1|root,32THV@2|Bacteria,4NTRX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8652524_2	1237149.C900_03832	6.905e-119	386.0	COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH2_k127_8652524_3	1237149.C900_03831	5.9e-110	360.0	COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,47NIJ@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH2_k127_8652524_5	1237149.C900_03830	1.083e-83	288.0	COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47T9B@768503|Cytophagia	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_8652524_4	929556.Solca_2425	6.152e-99	334.0	COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1IPQG@117747|Sphingobacteriia	976|Bacteroidetes	O	chaperone DnaJ	dnaJ2	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
DTH2_k127_8652524_8	929556.Solca_3458	1.182e-38	146.0	COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,1ITPA@117747|Sphingobacteriia	976|Bacteroidetes	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH2_k127_8652524_7	1538644.KO02_17375	1.653e-40	153.0	2C0VV@1|root,32R2M@2|Bacteria,4NQM5@976|Bacteroidetes,1ITKS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8652524_6	236814.IX39_15110	3.913e-45	168.0	COG5478@1|root,COG5478@2|Bacteria,4NPSX@976|Bacteroidetes,1IJ4S@117743|Flavobacteriia,3ZQKN@59732|Chryseobacterium	976|Bacteroidetes	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
DTH2_k127_8652524_1	1121286.AUMT01000012_gene2814	1.348e-158	513.0	COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,1HWM0@117743|Flavobacteriia,3ZR1E@59732|Chryseobacterium	976|Bacteroidetes	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
DTH2_k127_8652524_9	1123037.AUDE01000019_gene3340	5.073e-38	146.0	COG0517@1|root,COG0517@2|Bacteria,4NZCM@976|Bacteroidetes,1I9F3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH2_k127_8652524_13	1123037.AUDE01000019_gene3341	2.614e-13	74.0	2F97K@1|root,341IZ@2|Bacteria,4P44R@976|Bacteroidetes,1I9JY@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8652524_0	1123037.AUDE01000019_gene3342	2.753e-167	535.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1HWK0@117743|Flavobacteriia	976|Bacteroidetes	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
DTH2_k127_8671167_0	1121285.AUFK01000013_gene2527	0.0	1036.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1HXAQ@117743|Flavobacteriia,3ZNRY@59732|Chryseobacterium	976|Bacteroidetes	CI	Phenylacetic acid degradation protein PaaN	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,DUF1569,MaoC_dehydratas
DTH2_k127_8671167_1	1218108.KB908291_gene923	2.14e-101	335.0	COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1HXB6@117743|Flavobacteriia	976|Bacteroidetes	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_8671167_2	1121931.AUHG01000010_gene489	8.362e-32	125.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
DTH2_k127_8718501_0	1454007.JAUG01000018_gene1556	1.265e-86	288.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DTH2_k127_8718501_3	929556.Solca_1731	1.571e-32	132.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1ITUD@117747|Sphingobacteriia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
DTH2_k127_8718501_1	356851.JOAN01000037_gene499	1.767e-42	166.0	COG5429@1|root,COG5429@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
DTH2_k127_8718501_2	1121904.ARBP01000002_gene7285	9.555e-34	133.0	COG1393@1|root,COG1393@2|Bacteria,4NSA6@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
DTH2_k127_8718501_4	880073.Calab_1858	2.402e-29	126.0	COG1361@1|root,COG4447@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,TM_helix
DTH2_k127_8752282_0	760192.Halhy_5642	2.489e-161	526.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_8752282_4	700598.Niako_7211	3.39e-36	140.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH2_k127_8752282_2	700598.Niako_7212	1.161e-85	286.0	COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,1IQCF@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH2_k127_8752282_3	1121875.KB907547_gene3142	2.142e-43	163.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH2_k127_8752282_1	700598.Niako_7214	2.998e-155	495.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
DTH2_k127_875612_0	1313301.AUGC01000006_gene23	2.148e-139	445.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes	976|Bacteroidetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH2_k127_875612_3	761193.Runsl_3626	1.3e-36	142.0	COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia	976|Bacteroidetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
DTH2_k127_875612_1	755732.Fluta_1284	1.896e-114	397.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,1IKDB@117743|Flavobacteriia,2PC6J@246874|Cryomorphaceae	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12,TPR_8
DTH2_k127_875612_4	1353276.JADR01000003_gene2731	4.531e-05	56.0	COG2866@1|root,COG4935@1|root,COG2866@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	fpp1	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
DTH2_k127_875612_2	926559.JoomaDRAFT_3515	4.003e-48	191.0	COG2911@1|root,COG3209@1|root,COG3210@1|root,COG4677@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4677@2|Bacteria,COG5492@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_8784499_13	1202532.FF52_10258	4.12e-28	118.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,1I17C@117743|Flavobacteriia,2NT8G@237|Flavobacterium	976|Bacteroidetes	S	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
DTH2_k127_8784499_14	679935.Alfi_0605	7.832e-18	84.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,22UKC@171550|Rikenellaceae	976|Bacteroidetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DTH2_k127_8784499_9	929556.Solca_3252	3.071e-119	392.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DTH2_k127_8784499_4	1124780.ANNU01000044_gene492	6.451e-166	526.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_8784499_11	714943.Mucpa_2980	2.12e-57	208.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
DTH2_k127_8784499_6	945713.IALB_1297	1.694e-122	401.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH2_k127_8784499_10	1408473.JHXO01000013_gene534	3.61e-88	308.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,2FM7S@200643|Bacteroidia	976|Bacteroidetes	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
DTH2_k127_8784499_15	1121957.ATVL01000011_gene3915	9.454e-07	61.0	2CJG0@1|root,332HN@2|Bacteria,4NVWF@976|Bacteroidetes,47SVM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8784499_1	1286632.P278_21160	2.295e-250	780.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,1HXK2@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DTH2_k127_8784499_2	869213.JCM21142_41849	9.992e-212	675.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47JG7@768503|Cytophagia	976|Bacteroidetes	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH2_k127_8784499_0	1453500.AT05_07450	0.0	1010.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1HWKZ@117743|Flavobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
DTH2_k127_8784499_7	1408473.JHXO01000006_gene1037	6.384e-122	419.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_8784499_3	391598.FBBAL38_00905	2.943e-189	597.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1HXGD@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_8784499_5	743722.Sph21_1449	1.325e-152	490.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,1IPKJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_8784499_8	866536.Belba_1524	1.804e-120	391.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,47JHC@768503|Cytophagia	976|Bacteroidetes	F	Orotidine 5''-phosphate decarboxylase	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DTH2_k127_8784499_12	504487.JCM19302_3285	5.242e-50	181.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1HWT2@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
DTH2_k127_8805826_3	643867.Ftrac_1183	1.647e-131	428.0	COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,47KCQ@768503|Cytophagia	976|Bacteroidetes	E	Tryptophan 2,3-dioxygenase	kynA	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
DTH2_k127_8805826_4	1408473.JHXO01000010_gene3577	3.804e-91	309.0	COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes	976|Bacteroidetes	S	ribonuclease BN	yfkH	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
DTH2_k127_8805826_6	1356852.N008_11045	4.21e-22	105.0	COG0421@1|root,COG0421@2|Bacteria,4NPK5@976|Bacteroidetes	976|Bacteroidetes	E	Spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
DTH2_k127_8805826_1	869213.JCM21142_93814	5.503e-190	601.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_8805826_2	869213.JCM21142_62421	1.508e-179	575.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,47KB6@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
DTH2_k127_8805826_0	945713.IALB_2777	7.719e-287	906.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria	2|Bacteria	L	DNA topoisomerase type I activity	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
DTH2_k127_8805826_5	929556.Solca_4041	5.603e-80	274.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_8830370_3	926556.Echvi_2742	1.292e-45	172.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,47KWP@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_8830370_1	700598.Niako_6546	1.963e-81	278.0	COG0859@1|root,COG0859@2|Bacteria,4NMIH@976|Bacteroidetes,1IW27@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
DTH2_k127_8830370_4	700598.Niako_6546	3.802e-15	76.0	COG0859@1|root,COG0859@2|Bacteria,4NMIH@976|Bacteroidetes,1IW27@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
DTH2_k127_8830370_2	1353529.M899_1386	1.454e-76	264.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2MT12@213481|Bdellovibrionales,2WNU9@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8830370_0	929556.Solca_3477	1.44e-97	328.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1IQ92@117747|Sphingobacteriia	976|Bacteroidetes	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DTH2_k127_8873748_3	391612.CY0110_28224	3.341e-08	56.0	2DBIE@1|root,32TXH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8873748_0	153721.MYP_3151	6.398e-198	625.0	COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,47K3T@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH2_k127_8873748_2	1121889.AUDM01000012_gene1336	1.144e-53	192.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,1I173@117743|Flavobacteriia,2NST1@237|Flavobacterium	976|Bacteroidetes	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_8873748_1	485918.Cpin_0678	1.985e-72	250.0	COG0664@1|root,COG0664@2|Bacteria,4NFB1@976|Bacteroidetes,1IQHB@117747|Sphingobacteriia	976|Bacteroidetes	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_8890461_2	385682.AFSL01000084_gene1089	3.084e-34	132.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,2FNXA@200643|Bacteroidia,3XJTZ@558415|Marinilabiliaceae	976|Bacteroidetes	H	Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_8890461_4	1358423.N180_02605	1.807e-12	68.0	2BVK8@1|root,32Y0S@2|Bacteria,4NUUA@976|Bacteroidetes,1IZ0A@117747|Sphingobacteriia	976|Bacteroidetes	S	histone H1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hc1
DTH2_k127_8890461_0	1313301.AUGC01000001_gene1489	2.351e-188	597.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DTH2_k127_8890461_1	926562.Oweho_0344	4.941e-119	400.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,1IKDV@117743|Flavobacteriia,2PAQU@246874|Cryomorphaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
DTH2_k127_8890461_3	886293.Sinac_5869	7.711e-21	104.0	COG0457@1|root,COG0457@2|Bacteria,2IZ0D@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8922231_3	1218103.CIN01S_09_00440	7.246e-06	56.0	COG1520@1|root,COG1520@2|Bacteria,4NJA5@976|Bacteroidetes,1HXQ2@117743|Flavobacteriia,3ZPRM@59732|Chryseobacterium	976|Bacteroidetes	O	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8922231_1	1379698.RBG1_1C00001G1377	1.466e-11	77.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
DTH2_k127_8922231_2	1313421.JHBV01000027_gene1824	4.374e-06	58.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8922231_0	983544.Lacal_0934	1.926e-18	96.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes,1HXSH@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM Outer membrane protein, OmpA MotB, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_8924765_2	1519464.HY22_08815	1.127e-43	166.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
DTH2_k127_8924765_3	1279009.ADICEAN_01959	3.16e-24	108.0	2E3CB@1|root,32YBM@2|Bacteria,4NU80@976|Bacteroidetes,47Y2T@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
DTH2_k127_8924765_0	1121898.Q766_05980	4.571e-136	479.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,SprB
DTH2_k127_8924765_1	1107311.Q767_01615	1.543e-110	373.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
DTH2_k127_8931359_2	929703.KE386491_gene2923	3.459e-98	329.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia	976|Bacteroidetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_8931359_9	1346330.M472_20550	4.48e-10	69.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes,1IUMD@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4271)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
DTH2_k127_8931359_3	926562.Oweho_2716	3.989e-92	309.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1HWMQ@117743|Flavobacteriia,2PA6W@246874|Cryomorphaceae	976|Bacteroidetes	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
DTH2_k127_8931359_5	1168289.AJKI01000002_gene2553	2.593e-56	201.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia,3XK6J@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_8931359_10	1123248.KB893348_gene259	9.332e-10	71.0	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8931359_7	929556.Solca_2795	2.314e-25	116.0	2DC2E@1|root,2ZCMH@2|Bacteria,4NN02@976|Bacteroidetes,1IRWH@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_8931359_6	755732.Fluta_2398	1.339e-49	192.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8931359_8	153721.MYP_4561	1.66e-15	83.0	2FJZD@1|root,34BMR@2|Bacteria,4P57U@976|Bacteroidetes,47VSH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8931359_0	313606.M23134_07119	1.859e-279	880.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,47Y3C@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8931359_4	1313301.AUGC01000001_gene1456	1.382e-81	294.0	COG0747@1|root,COG4288@1|root,COG0747@2|Bacteria,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes	976|Bacteroidetes	E	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
DTH2_k127_8931359_1	714943.Mucpa_5553	2.867e-103	347.0	COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,1IPAV@117747|Sphingobacteriia	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_8962471_1	1123248.KB893337_gene2498	2.43e-148	479.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1IQ6R@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_8962471_0	1121904.ARBP01000006_gene3845	7.41e-155	501.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47MT4@768503|Cytophagia	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10,1.5.1.7	ko:K00290,ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R02315	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DTH2_k127_8962471_2	643867.Ftrac_1152	2.672e-125	416.0	COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia	976|Bacteroidetes	V	efflux protein, MATE family	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
DTH2_k127_8962471_3	926549.KI421517_gene3122	2.995e-97	336.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,47K4G@768503|Cytophagia	976|Bacteroidetes	M	COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_8965211_2	755732.Fluta_1117	8.717e-174	559.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia,2PAC5@246874|Cryomorphaceae	976|Bacteroidetes	M	TIGRFAM outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
DTH2_k127_8965211_4	1408473.JHXO01000004_gene153	6.821e-51	187.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,2FQDW@200643|Bacteroidia	976|Bacteroidetes	M	membrane	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_8965211_5	886377.Murru_1928	9.107e-18	90.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1I1AX@117743|Flavobacteriia	976|Bacteroidetes	M	membrane	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_8965211_1	1408433.JHXV01000027_gene3728	4.487e-202	667.0	COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia	976|Bacteroidetes	KT	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Reg_prop,Y_Y_Y
DTH2_k127_8965211_3	929556.Solca_2939	5.176e-120	392.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,1IPZH@117747|Sphingobacteriia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
DTH2_k127_8965211_6	761193.Runsl_3990	3.994e-05	54.0	28Q42@1|root,2ZCME@2|Bacteria,4NMXP@976|Bacteroidetes,47PFS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8965211_0	1453500.AT05_11630	5.37e-288	894.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1HXYZ@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DTH2_k127_8989365_5	1123008.KB905697_gene3164	4.318e-84	282.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,2FNGP@200643|Bacteroidia,22VVQ@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DTH2_k127_8989365_3	1121931.AUHG01000016_gene1033	3.946e-160	514.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,1HYME@117743|Flavobacteriia	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_8989365_0	927658.AJUM01000047_gene2906	1.296e-242	760.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,3XKNN@558415|Marinilabiliaceae	976|Bacteroidetes	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
DTH2_k127_8989365_2	153721.MYP_4656	1.088e-170	562.0	COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
DTH2_k127_8989365_1	1346330.M472_05445	3.385e-223	708.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,1IPAP@117747|Sphingobacteriia	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
DTH2_k127_8989365_6	331113.SNE_A09170	1.11e-68	238.0	COG2094@1|root,COG2094@2|Bacteria,2JG1T@204428|Chlamydiae	204428|Chlamydiae	L	Belongs to the DNA glycosylase MPG family	CP_0248	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DTH2_k127_8989365_8	1408433.JHXV01000010_gene507	3.704e-09	64.0	2A3J1@1|root,30S22@2|Bacteria,4PCED@976|Bacteroidetes,1ICTW@117743|Flavobacteriia,2PC5J@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8989365_7	1408433.JHXV01000010_gene508	1.425e-41	166.0	29N3N@1|root,33PNI@2|Bacteria,4P1TW@976|Bacteroidetes,1IMS9@117743|Flavobacteriia,2PBW3@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8989365_4	926549.KI421517_gene2587	8.67e-155	497.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH2_k127_9024808_14	880073.Calab_1823	2.572e-36	158.0	COG0860@1|root,COG4412@1|root,COG0860@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	bpr	GO:0005575,GO:0005576	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K09955,ko:K13276	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036,ko03110	-	-	-	CHAP,CarbopepD_reg_2,CarboxypepD_reg,GBS_Bsp-like,Glyco_hydro_25,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8,SH3_5,VanY,YSIRK_signal
DTH2_k127_9024808_11	393921.HQ45_00900	5.974e-52	188.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,2FSTK@200643|Bacteroidia,22YUQ@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_9024808_4	1453500.AT05_00420	6.932e-145	477.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9024808_12	1453500.AT05_05495	2.061e-49	187.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
DTH2_k127_9024808_15	945713.IALB_2657	1.407e-06	58.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9024808_5	1121904.ARBP01000009_gene4339	1.271e-108	365.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_9024808_2	1349785.BAUG01000016_gene1208	1.057e-162	524.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1HXEV@117743|Flavobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
DTH2_k127_9024808_1	1185876.BN8_06139	1.529e-177	563.0	COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
DTH2_k127_9024808_9	926562.Oweho_2361	1.055e-77	271.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia,2PBQF@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_9024808_0	485918.Cpin_6617	7.514e-280	878.0	COG0155@1|root,COG1895@1|root,COG0155@2|Bacteria,COG1895@2|Bacteria,4NENW@976|Bacteroidetes,1INY4@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitrite and sulphite reductase 4Fe-4S	cysI	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr,TusA
DTH2_k127_9024808_8	1408813.AYMG01000010_gene347	4.994e-96	320.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes,1IRKW@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the precorrin methyltransferase family	cobA	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
DTH2_k127_9024808_10	153721.MYP_3703	6.188e-63	223.0	COG1648@1|root,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,47PPT@768503|Cytophagia	976|Bacteroidetes	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
DTH2_k127_9024808_13	1500281.JQKZ01000008_gene2521	1.253e-40	154.0	COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,1I1Z9@117743|Flavobacteriia,3ZRU5@59732|Chryseobacterium	976|Bacteroidetes	K	Rrf2 family transcriptional regulator	cymR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH2_k127_9024808_6	926549.KI421517_gene819	1.107e-106	357.0	COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes,47YJA@768503|Cytophagia	976|Bacteroidetes	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304,ko:K07090	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M,TauE
DTH2_k127_9024808_7	509635.N824_18300	1.624e-106	349.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1IQ9Q@117747|Sphingobacteriia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH2_k127_9024808_3	1123248.KB893385_gene4790	8.765e-149	475.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,1INWY@117747|Sphingobacteriia	976|Bacteroidetes	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH2_k127_903460_3	1408433.JHXV01000038_gene2198	1.745e-41	169.0	COG2885@1|root,COG2885@2|Bacteria,4NRRF@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DTH2_k127_903460_4	1123257.AUFV01000002_gene2346	1.982e-12	79.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RCNJ@1224|Proteobacteria,1S2JT@1236|Gammaproteobacteria,1XA5N@135614|Xanthomonadales	135614|Xanthomonadales	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_903460_1	693979.Bache_1502	1.003e-66	235.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,2FKZG@200643|Bacteroidia,4AMW9@815|Bacteroidaceae	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
DTH2_k127_903460_0	261292.Nit79A3_3094	8.636e-78	266.0	COG1266@1|root,COG1266@2|Bacteria,1R5BW@1224|Proteobacteria,2W2E1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DTH2_k127_903460_2	1313421.JHBV01000023_gene5122	4.618e-62	224.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1IP77@117747|Sphingobacteriia	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
DTH2_k127_9042891_0	468059.AUHA01000002_gene413	4.62e-147	486.0	COG0457@1|root,COG0457@2|Bacteria,4NE2V@976|Bacteroidetes,1INS7@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
DTH2_k127_9042891_3	866536.Belba_1938	5.506e-17	85.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes,47R73@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
DTH2_k127_9042891_2	762903.Pedsa_2022	3.33e-61	215.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1IRT0@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DTH2_k127_9042891_1	1150600.ADIARSV_0240	6.336e-64	223.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
DTH2_k127_9043195_2	1408433.JHXV01000002_gene285	3.076e-189	596.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1HWP2@117743|Flavobacteriia,2PAB9@246874|Cryomorphaceae	976|Bacteroidetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DTH2_k127_9043195_4	1347342.BN863_15680	1.221e-116	391.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
DTH2_k127_9043195_7	1453500.AT05_08735	7.883e-50	184.0	COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,1HWKF@117743|Flavobacteriia	976|Bacteroidetes	O	PFAM Scaffold protein Nfu NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
DTH2_k127_9043195_0	385682.AFSL01000096_gene579	1.298e-230	725.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,2FNMT@200643|Bacteroidia,3XIJE@558415|Marinilabiliaceae	976|Bacteroidetes	H	Fumarate reductase flavoprotein C-term	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_9043195_3	391603.FBALC1_03842	3.692e-183	599.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,1IIH0@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
DTH2_k127_9043195_10	1166018.FAES_2981	3.548e-24	105.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,47S0M@768503|Cytophagia	976|Bacteroidetes	P	PFAM Heavy metal transport detoxification protein	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
DTH2_k127_9043195_5	1250232.JQNJ01000001_gene2059	3.151e-88	293.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia	976|Bacteroidetes	S	isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_9043195_9	755732.Fluta_0947	1.892e-30	132.0	2A7NQ@1|root,30WKT@2|Bacteria,4PA0D@976|Bacteroidetes,1IF21@117743|Flavobacteriia,2PBZY@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9043195_1	929556.Solca_4363	6.431e-219	696.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1IPN2@117747|Sphingobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH2_k127_9043195_6	886379.AEWI01000064_gene2315	1.055e-74	259.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,2FNMJ@200643|Bacteroidia,3XJ7Z@558415|Marinilabiliaceae	976|Bacteroidetes	S	Eukaryotic integral membrane protein (DUF1751)	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
DTH2_k127_9043195_8	1347342.BN863_8270	1.205e-40	153.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
DTH2_k127_9073747_0	385682.AFSL01000099_gene3	2.166e-164	526.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,2FMTV@200643|Bacteroidia,3XJHM@558415|Marinilabiliaceae	976|Bacteroidetes	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_9073747_1	643867.Ftrac_2007	2.766e-118	393.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,47KQX@768503|Cytophagia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
DTH2_k127_9073747_2	153721.MYP_3528	6.826e-63	221.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,47MZS@768503|Cytophagia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DTH2_k127_9073747_3	1408473.JHXO01000008_gene2881	6.682e-54	207.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,2FQ12@200643|Bacteroidia	976|Bacteroidetes	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
DTH2_k127_912038_0	1150600.ADIARSV_2511	0.0	1588.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH2_k127_9158146_2	468059.AUHA01000002_gene1235	1.218e-128	417.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
DTH2_k127_9158146_6	886379.AEWI01000047_gene3068	2.548e-57	205.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,2FN5J@200643|Bacteroidia,3XJJ1@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DTH2_k127_9158146_4	1121012.AUKX01000021_gene1698	1.329e-75	258.0	COG0563@1|root,COG0634@1|root,COG0563@2|Bacteria,COG0634@2|Bacteria,4NG7J@976|Bacteroidetes,1HWR5@117743|Flavobacteriia,23FWR@178469|Arenibacter	976|Bacteroidetes	F	AAA domain	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
DTH2_k127_9158146_1	760192.Halhy_2958	2.753e-152	488.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,1IP1F@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DTH2_k127_9158146_0	1123248.KB893318_gene4103	4.553e-315	982.0	COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia	976|Bacteroidetes	E	COG0308 Aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH2_k127_9158146_5	1358423.N180_09500	9.46e-60	212.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,1IRX6@117747|Sphingobacteriia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
DTH2_k127_9158146_8	391596.PBAL39_23502	1.002e-29	125.0	2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1ITQK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9158146_7	1168289.AJKI01000003_gene2793	7.444e-42	160.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,2FRKS@200643|Bacteroidia,3XK0T@558415|Marinilabiliaceae	976|Bacteroidetes	I	Acid phosphatase homologues	ybjG	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DTH2_k127_9158146_9	468059.AUHA01000002_gene472	3.934e-22	100.0	COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,1IUJE@117747|Sphingobacteriia	976|Bacteroidetes	D	CrcB-like protein, Camphor Resistance (CrcB)	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
DTH2_k127_9158146_3	1408473.JHXO01000006_gene1066	1.961e-99	335.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_9183128_0	1408433.JHXV01000010_gene496	1.284e-142	473.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_9183128_1	880071.Fleli_1265	1.028e-09	62.0	2EV82@1|root,33NNS@2|Bacteria,4NYTU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9236222_9	1121957.ATVL01000006_gene3308	1.933e-29	124.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,47P98@768503|Cytophagia	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
DTH2_k127_9236222_1	755732.Fluta_0923	3.833e-174	553.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia,2PA7J@246874|Cryomorphaceae	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DTH2_k127_9236222_7	1168034.FH5T_08865	3.802e-67	237.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,2FM5H@200643|Bacteroidia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
DTH2_k127_9236222_6	1313421.JHBV01000044_gene2926	7.957e-68	246.0	COG0349@1|root,COG0349@2|Bacteria,4NP62@976|Bacteroidetes	976|Bacteroidetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
DTH2_k127_9236222_5	1408473.JHXO01000001_gene2167	2.75e-99	336.0	COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes	976|Bacteroidetes	F	amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DTH2_k127_9236222_2	929703.KE386491_gene3152	1.944e-154	495.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,47KHN@768503|Cytophagia	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_9236222_4	714943.Mucpa_1297	4.924e-132	428.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH2_k127_9236222_11	906888.JCM19314_649	6.502e-12	72.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_2,TPR_8
DTH2_k127_9236222_0	762903.Pedsa_2681	1.547e-189	613.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1IR9Y@117747|Sphingobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
DTH2_k127_9236222_3	714943.Mucpa_1462	5.208e-142	464.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
DTH2_k127_9236222_8	1121481.AUAS01000005_gene1935	1.088e-65	227.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_9256978_5	743722.Sph21_1340	2.455e-50	186.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9256978_1	926562.Oweho_3003	8.043e-138	451.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DTH2_k127_9256978_7	231434.JQJH01000014_gene953	1.591e-29	122.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,3NB0J@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH2_k127_9256978_3	1122226.AUHX01000007_gene2712	4.375e-109	362.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia	976|Bacteroidetes	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DTH2_k127_9256978_6	1392488.JHZY01000004_gene2723	1.573e-31	126.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia,2XJHQ@283735|Leeuwenhoekiella	976|Bacteroidetes	L	bacterial (prokaryotic) histone like domain	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_9256978_8	1122621.ATZA01000010_gene197	1.452e-23	109.0	COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,1IQYF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
DTH2_k127_9256978_0	468059.AUHA01000002_gene680	1.653e-199	633.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
DTH2_k127_9256978_4	1317122.ATO12_01850	3.538e-52	186.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia,2YJMG@290174|Aquimarina	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH2_k127_9256978_2	391596.PBAL39_09886	7.338e-122	394.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH2_k127_9271209_8	762903.Pedsa_1038	2.045e-08	55.0	COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1IP9M@117747|Sphingobacteriia	976|Bacteroidetes	M	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_9271209_3	643867.Ftrac_1237	9.062e-115	392.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia	976|Bacteroidetes	M	COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_9271209_1	926562.Oweho_2126	3.887e-267	829.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HYE9@117743|Flavobacteriia,2PAEZ@246874|Cryomorphaceae	976|Bacteroidetes	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_9271209_6	1123248.KB893315_gene3022	1.432e-18	99.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IXGM@117747|Sphingobacteriia	976|Bacteroidetes	S	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_9271209_2	929556.Solca_3842	1.673e-247	803.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
DTH2_k127_9271209_4	269798.CHU_3500	1.706e-36	142.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
DTH2_k127_9271209_7	313590.MED134_12876	2.194e-13	72.0	COG1826@1|root,COG1826@2|Bacteria,4NSAK@976|Bacteroidetes,1I40K@117743|Flavobacteriia,37FB2@326319|Dokdonia	976|Bacteroidetes	U	mttA/Hcf106 family	-	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_9271209_0	743722.Sph21_2971	2.537e-267	857.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1IP7W@117747|Sphingobacteriia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DTH2_k127_9271209_5	509635.N824_12275	2.925e-20	91.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,1ISN4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9281156_1	929556.Solca_4296	2.16e-90	316.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1INT0@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
DTH2_k127_9281156_0	1237149.C900_01198	3.199e-319	993.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
DTH2_k127_9281156_2	929556.Solca_1740	2.401e-16	80.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1ISYC@117747|Sphingobacteriia	976|Bacteroidetes	K	acr, cog1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
DTH2_k127_9325238_3	1237149.C900_04788	3.955e-05	51.0	2E691@1|root,32WA1@2|Bacteria,4NT8M@976|Bacteroidetes,47R10@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9325238_2	1408433.JHXV01000014_gene3639	1.607e-42	169.0	COG2067@1|root,COG2067@2|Bacteria,4NIU4@976|Bacteroidetes,1IFTS@117743|Flavobacteriia,2PBTH@246874|Cryomorphaceae	976|Bacteroidetes	I	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_9325238_1	926549.KI421517_gene2679	6.686e-50	187.0	2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
DTH2_k127_9325238_0	929703.KE386491_gene3971	1.538e-294	907.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_9331523_3	459349.CLOAM0656	1.918e-62	217.0	COG1208@1|root,COG1208@2|Bacteria,2NPHW@2323|unclassified Bacteria	2|Bacteria	JM	Nucleotidyl transferase	mpg2	-	2.7.7.13	ko:K00966,ko:K21210	ko00051,ko00520,ko01059,ko01100,ko01110,ko01130,map00051,map00520,map01059,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R11429	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_9331523_2	113395.AXAI01000011_gene6407	4.159e-75	261.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2U8DY@28211|Alphaproteobacteria,3K629@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_9331523_1	866536.Belba_3332	6.298e-76	267.0	COG0438@1|root,COG0438@2|Bacteria,4NNVW@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH2_k127_9331523_6	159087.Daro_1253	4.812e-34	142.0	COG2230@1|root,COG2230@2|Bacteria,1QWG5@1224|Proteobacteria,2W08Z@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_9331523_4	153721.MYP_500	2.02e-61	230.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,47MXC@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_9331523_0	929556.Solca_2806	5.475e-88	296.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes,1INQ4@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_9331523_5	888059.HMPREF9071_1484	3.913e-34	136.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia,1ES0P@1016|Capnocytophaga	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DTH2_k127_9341213_0	926562.Oweho_1567	2.767e-261	823.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1HXSC@117743|Flavobacteriia,2PA4Q@246874|Cryomorphaceae	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
DTH2_k127_9341213_1	762903.Pedsa_3005	4.6e-63	222.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1IRJ2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
DTH2_k127_9341213_2	929556.Solca_3900	5.319e-63	226.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1IQW1@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DTH2_k127_9384045_5	1458275.AZ34_04170	2.322e-08	58.0	28QPF@1|root,2ZD50@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9384045_3	1173023.KE650771_gene4723	2.602e-11	65.0	COG2227@1|root,COG2227@2|Bacteria,1GA74@1117|Cyanobacteria	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_9384045_0	713587.THITH_12500	3.784e-173	585.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1QP7Y@1224|Proteobacteria,1RR12@1236|Gammaproteobacteria,1WXJ8@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_23
DTH2_k127_9384045_2	1144319.PMI16_04133	2.319e-29	138.0	COG1216@1|root,COG5010@1|root,COG1216@2|Bacteria,COG5010@2|Bacteria,1R2RC@1224|Proteobacteria,2WICM@28216|Betaproteobacteria	2|Bacteria	U	COG0457 FOG TPR repeat	M1-734	-	-	ko:K07272,ko:K13486,ko:K20543,ko:K21007	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	1.B.55.3	-	-	DUF707,SMI1_KNR4
DTH2_k127_9384045_1	580332.Slit_0610	1.537e-54	199.0	COG1216@1|root,COG5010@1|root,COG1216@2|Bacteria,COG5010@2|Bacteria,1RB30@1224|Proteobacteria,2WHYB@28216|Betaproteobacteria,44WN0@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_9384188_2	761193.Runsl_5254	5.477e-109	363.0	COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,Response_reg,cNMP_binding
DTH2_k127_9384188_4	1123248.KB893316_gene4616	3.568e-56	200.0	COG1881@1|root,COG1881@2|Bacteria,4NH14@976|Bacteroidetes,1IT2Y@117747|Sphingobacteriia	976|Bacteroidetes	S	Raf kinase inhibitor-like protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
DTH2_k127_9384188_6	1137281.D778_02225	8.766e-17	85.0	2CYW5@1|root,32T50@2|Bacteria,4NS73@976|Bacteroidetes,1I3WS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9384188_0	1121373.KB903628_gene1442	4.214e-154	493.0	COG0524@1|root,COG0524@2|Bacteria,4NFJ9@976|Bacteroidetes,47KA2@768503|Cytophagia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	ydjH	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH2_k127_9384188_3	929556.Solca_4343	1.458e-80	283.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_9384188_5	926549.KI421517_gene1854	3.757e-21	104.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
DTH2_k127_9384188_1	929556.Solca_4341	2.811e-110	373.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IR0N@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
DTH2_k127_9387693_3	1107311.Q767_11460	6.993e-35	138.0	COG0454@1|root,COG0456@2|Bacteria,4NU7P@976|Bacteroidetes,1I4UM@117743|Flavobacteriia,2NVZE@237|Flavobacterium	976|Bacteroidetes	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_9387693_0	1408473.JHXO01000006_gene1161	2.232e-108	366.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,2FMTF@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
DTH2_k127_9387693_6	927658.AJUM01000037_gene2018	1.054e-15	86.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,2FN88@200643|Bacteroidia,3XJGV@558415|Marinilabiliaceae	976|Bacteroidetes	M	Sulfatase	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_9387693_4	153721.MYP_2220	4.484e-30	129.0	28PIV@1|root,2ZC8P@2|Bacteria,4NGE2@976|Bacteroidetes,47XX6@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
DTH2_k127_9387693_1	1121373.KB903629_gene362	4.189e-72	269.0	COG0457@1|root,COG0457@2|Bacteria	1121373.KB903629_gene362|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9387693_7	945713.IALB_2064	2.709e-06	61.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_2064|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9387693_2	643867.Ftrac_0719	5.939e-43	171.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,47QI6@768503|Cytophagia	976|Bacteroidetes	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
DTH2_k127_9387693_5	909663.KI867150_gene216	3.781e-24	106.0	COG1807@1|root,COG1807@2|Bacteria,1R3XN@1224|Proteobacteria,42P5N@68525|delta/epsilon subdivisions,2WKH2@28221|Deltaproteobacteria,2MQ8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_9394130_1	313598.MED152_09160	2.782e-43	160.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia,3VWJ9@52959|Polaribacter	976|Bacteroidetes	L	Single-strand binding protein family	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH2_k127_9394130_0	1408433.JHXV01000016_gene1828	2.714e-232	748.0	COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia,2PA94@246874|Cryomorphaceae	976|Bacteroidetes	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9426383_0	1124780.ANNU01000020_gene3278	0.0	1289.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
DTH2_k127_9426383_11	926562.Oweho_0417	1.663e-22	100.0	COG2921@1|root,COG2921@2|Bacteria,4PA5G@976|Bacteroidetes,1IGIZ@117743|Flavobacteriia,2PB80@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF493)	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
DTH2_k127_9426383_12	338963.Pcar_2636	1.962e-12	70.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,42W9B@68525|delta/epsilon subdivisions,2WS2I@28221|Deltaproteobacteria,43SRM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
DTH2_k127_9426383_10	717785.HYPMC_3214	6.187e-23	103.0	COG2940@1|root,COG2940@2|Bacteria,1N3VM@1224|Proteobacteria,2UDY0@28211|Alphaproteobacteria,3N93Y@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
DTH2_k127_9426383_1	269798.CHU_3530	5.167e-279	867.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,47Y0J@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DTH2_k127_9426383_8	1122176.KB903537_gene1694	8.235e-38	150.0	COG0671@1|root,COG0671@2|Bacteria,4NV5Q@976|Bacteroidetes,1ITA7@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DTH2_k127_9426383_9	1353276.JADR01000001_gene286	6.07e-31	128.0	COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,1I21X@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DTH2_k127_9426383_3	153721.MYP_1783	1.258e-183	586.0	COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,47JMA@768503|Cytophagia	976|Bacteroidetes	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH2_k127_9426383_6	266748.HY04_13380	3.924e-83	280.0	COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,1HWU0@117743|Flavobacteriia,3ZNK7@59732|Chryseobacterium	976|Bacteroidetes	EH	Anthranilate synthase subunit II	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH2_k127_9426383_4	1121904.ARBP01000006_gene4079	2.218e-127	414.0	COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,47KKR@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
DTH2_k127_9426383_5	1120966.AUBU01000001_gene919	4.939e-86	291.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,47JRX@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
DTH2_k127_9426383_7	1144313.PMI10_00155	2.691e-57	205.0	COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1I1CD@117743|Flavobacteriia,2NVBQ@237|Flavobacterium	976|Bacteroidetes	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
DTH2_k127_9426383_2	746697.Aeqsu_0648	2.19e-188	591.0	COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,1HXYK@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH2_k127_9437378_3	1123248.KB893316_gene4662	1.463e-64	223.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,1IWQ3@117747|Sphingobacteriia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_9437378_1	946077.W5A_06446	6.23e-99	336.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1I95J@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9437378_5	1121935.AQXX01000117_gene5104	5.004e-62	218.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,1SQYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9437378_8	1461577.CCMH01000014_gene584	0.0001754	45.0	2DRFB@1|root,33BGM@2|Bacteria,4NXIN@976|Bacteroidetes,1I6SW@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9437378_2	926562.Oweho_1092	2.872e-85	301.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9437378_0	1392490.JHZX01000001_gene841	2.593e-121	398.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,1HXBB@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
DTH2_k127_9437378_6	929713.NIASO_03685	5.597e-46	170.0	COG2346@1|root,COG2346@2|Bacteria,4NQCV@976|Bacteroidetes	976|Bacteroidetes	S	Pfam Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
DTH2_k127_9437378_4	1270196.JCKI01000004_gene877	2.007e-64	222.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1ISBR@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
DTH2_k127_9437378_7	269798.CHU_0569	4.671e-36	151.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_9440909_1	926562.Oweho_1772	2.083e-207	648.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2PAB6@246874|Cryomorphaceae	976|Bacteroidetes	C	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_9440909_3	1380384.JADN01000006_gene2393	3.151e-136	447.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1HY7Q@117743|Flavobacteriia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_9440909_2	927658.AJUM01000034_gene127	4.354e-175	563.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,2FQNC@200643|Bacteroidia,3XJTF@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_9440909_5	755732.Fluta_2549	1.527e-94	319.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_9440909_0	755732.Fluta_2550	6.131e-291	938.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,2PAHV@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DTH2_k127_9440909_4	509635.N824_12965	5.464e-125	413.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1IPX7@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9440909_6	1237149.C900_01767	6.82e-13	68.0	COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia	976|Bacteroidetes	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
DTH2_k127_9482004_0	362418.IW19_12325	1.734e-132	433.0	COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,1HXD8@117743|Flavobacteriia,2NSG0@237|Flavobacterium	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_9482004_1	1121373.KB903625_gene3160	2.451e-29	123.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_9507648_2	929556.Solca_2064	1.073e-71	254.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_9507648_1	468059.AUHA01000003_gene1959	3.925e-130	422.0	COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,1IQBU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_9507648_0	1211813.CAPH01000006_gene1474	1.908e-226	709.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia,22UTF@171550|Rikenellaceae	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_9598529_2	742817.HMPREF9449_00340	6.835e-18	83.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia,22WPG@171551|Porphyromonadaceae	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_9598529_1	929556.Solca_2291	1.357e-95	322.0	COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,1IPQ2@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH2_k127_9598529_0	926562.Oweho_1753	7.484e-141	453.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1HXWT@117743|Flavobacteriia,2PAAG@246874|Cryomorphaceae	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
DTH2_k127_9598529_3	755732.Fluta_3556	4.28e-05	51.0	29N3N@1|root,32D2M@2|Bacteria,4NRTM@976|Bacteroidetes,1ICPZ@117743|Flavobacteriia,2PBKH@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9633525_1	401053.AciPR4_4188	8.13e-47	172.0	COG1595@1|root,COG1595@2|Bacteria,3Y4KQ@57723|Acidobacteria,2JJAR@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_9633525_2	1185876.BN8_00342	9.972e-18	87.0	2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,47SBQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9633525_0	525373.HMPREF0766_10652	3.833e-61	216.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DTH2_k127_9633525_3	1178825.ALIH01000001_gene2581	9.714e-06	56.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1HY9Y@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
DTH2_k127_9654857_1	1121904.ARBP01000005_gene4844	3.803e-36	139.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47N2D@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF4369)	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
DTH2_k127_9654857_6	926549.KI421517_gene2182	2.199e-18	91.0	COG2146@1|root,COG2146@2|Bacteria,4NV1B@976|Bacteroidetes,47S5J@768503|Cytophagia	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9654857_5	1168289.AJKI01000008_gene711	3.389e-19	93.0	COG0614@1|root,COG0614@2|Bacteria,4NQ88@976|Bacteroidetes,2G3C0@200643|Bacteroidia,3XM1G@558415|Marinilabiliaceae	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_9654857_0	153721.MYP_4648	5.488e-152	485.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,47KEK@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
DTH2_k127_9654857_3	761193.Runsl_1859	4.295e-26	126.0	COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,47M4T@768503|Cytophagia	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_9654857_4	1408433.JHXV01000009_gene1250	3.576e-24	120.0	COG4935@1|root,COG4935@2|Bacteria,4PP7N@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9654857_2	1121895.Q765_19150	1.501e-31	143.0	COG1345@1|root,COG3291@1|root,COG3468@1|root,COG1345@2|Bacteria,COG3291@2|Bacteria,COG3468@2|Bacteria,4NFVP@976|Bacteroidetes,1IIIJ@117743|Flavobacteriia,2P0E0@237|Flavobacterium	976|Bacteroidetes	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494,Ig_3,LTD
DTH2_k127_9654857_7	746697.Aeqsu_2225	1.428e-11	78.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
DTH2_k127_9713692_1	313606.M23134_02336	2.373e-105	349.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,47KKI@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
DTH2_k127_9713692_3	1550091.JROE01000009_gene287	2.375e-22	105.0	29CCT@1|root,2ZZB9@2|Bacteria,4NM9K@976|Bacteroidetes,1IRVA@117747|Sphingobacteriia	976|Bacteroidetes	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
DTH2_k127_9713692_0	762903.Pedsa_2259	1.286e-209	660.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
DTH2_k127_9713692_2	595460.RRSWK_07231	1.097e-23	106.0	COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9713692_4	153721.MYP_5039	2.795e-21	100.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
DTH2_k127_9753927_1	1358423.N180_10575	5.876e-41	157.0	COG0642@1|root,COG3290@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,4NG0Y@976|Bacteroidetes,1IPHZ@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DTH2_k127_9753927_3	1189612.A33Q_3152	2.135e-06	52.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,47K97@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23,HlyD_D4
DTH2_k127_9753927_0	1237149.C900_04563	8.604e-81	289.0	28KVV@1|root,2ZACB@2|Bacteria,4NHPI@976|Bacteroidetes,47MDK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9753927_2	1237149.C900_03829	7.01e-25	109.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
DTH2_k127_9775497_1	755732.Fluta_4067	3.825e-98	327.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia,2PBCM@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_9775497_0	1123248.KB893359_gene2225	1.867e-199	628.0	COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,1IP1W@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
DTH2_k127_9775497_2	755732.Fluta_0823	7.918e-75	261.0	2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,1HY5Y@117743|Flavobacteriia,2PAVX@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
DTH2_k127_9775497_3	143224.JQMD01000002_gene3647	3.847e-19	98.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_9837677_6	649349.Lbys_0384	9.477e-27	129.0	COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
DTH2_k127_9837677_2	515635.Dtur_1285	3.113e-53	216.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
DTH2_k127_9837677_3	1227739.Hsw_1607	2.833e-48	199.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,47K6N@768503|Cytophagia	976|Bacteroidetes	DZ	Galactose oxidase, central domain	nanM	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6
DTH2_k127_9837677_5	1416760.AYMS01000056_gene3013	7.65e-28	131.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,47ISC@76831|Myroides	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_9837677_1	313606.M23134_00400	4.283e-57	223.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,47K6N@768503|Cytophagia	976|Bacteroidetes	DZ	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,TIG
DTH2_k127_9837677_0	1408433.JHXV01000015_gene1734	2.222e-145	481.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4P03T@976|Bacteroidetes	976|Bacteroidetes	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
DTH2_k127_9837677_7	385682.AFSL01000074_gene1247	1.511e-08	66.0	COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0E9@200643|Bacteroidia,3XJCN@558415|Marinilabiliaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
DTH2_k127_9837677_4	385682.AFSL01000006_gene2376	2.769e-29	123.0	COG0642@1|root,COG2205@2|Bacteria,4NX2D@976|Bacteroidetes,2G28Q@200643|Bacteroidia,3XKD2@558415|Marinilabiliaceae	976|Bacteroidetes	T	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
DTH2_k127_9837677_8	56107.Cylst_4550	2.637e-07	54.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_9870965_0	1313301.AUGC01000005_gene265	2.994e-283	890.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
DTH2_k127_9870965_3	1123276.KB893279_gene2202	4.678e-53	198.0	COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,47R0N@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_9870965_4	765952.PUV_26370	1.965e-34	134.0	2E3V1@1|root,32YSA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9870965_2	929562.Emtol_3530	6.644e-76	260.0	COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia	976|Bacteroidetes	S	PFAM O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
DTH2_k127_9870965_5	379066.GAU_3070	8.123e-32	126.0	COG5531@1|root,COG5531@2|Bacteria,1ZTZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
DTH2_k127_9870965_1	755732.Fluta_0844	6.418e-159	518.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH2_k127_9870965_8	1453498.LG45_06150	0.0004951	51.0	COG3291@1|root,COG4733@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4NIM6@976|Bacteroidetes,1HX50@117743|Flavobacteriia,2NU2T@237|Flavobacterium	976|Bacteroidetes	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH2_k127_9870965_7	755732.Fluta_0518	9.105e-15	83.0	2A8FU@1|root,30XHS@2|Bacteria,4PAYV@976|Bacteroidetes,1ICSJ@117743|Flavobacteriia,2PC02@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9870965_6	714943.Mucpa_0995	3.252e-30	133.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH2_k127_9881051_0	929556.Solca_4088	4.609e-218	688.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
DTH2_k127_9881051_1	1150600.ADIARSV_2416	6.839e-148	480.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
DTH2_k127_9881051_2	1042376.AFPK01000063_gene1133	2.472e-18	85.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia,405UM@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_9907731_1	1313421.JHBV01000031_gene1447	1.115e-36	154.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes	976|Bacteroidetes	Q	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
DTH2_k127_9907731_2	1121904.ARBP01000007_gene2943	2.553e-32	143.0	COG0535@1|root,COG0535@2|Bacteria,4NEGK@976|Bacteroidetes,47KFZ@768503|Cytophagia	976|Bacteroidetes	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9907731_0	1107311.Q767_12450	3.016e-161	513.0	COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1HWQC@117743|Flavobacteriia,2NSCK@237|Flavobacterium	976|Bacteroidetes	C	Pyruvate dehydrogenase	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_9907731_3	1408433.JHXV01000001_gene808	1.832e-21	106.0	COG2006@1|root,COG2006@2|Bacteria,4PHHF@976|Bacteroidetes,1ICS8@117743|Flavobacteriia,2PBZ7@246874|Cryomorphaceae	976|Bacteroidetes	S	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9933496_2	1168034.FH5T_05150	2.946e-62	230.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia	976|Bacteroidetes	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_9933496_1	1121889.AUDM01000021_gene543	1.969e-69	248.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1HY38@117743|Flavobacteriia,2NV9W@237|Flavobacterium	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
DTH2_k127_9933496_0	1408813.AYMG01000028_gene2418	4.208e-87	291.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1INR4@117747|Sphingobacteriia	976|Bacteroidetes	F	Amidophosphoribosyltransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH2_k127_9943612_0	1121957.ATVL01000008_gene4046	6.127e-223	700.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH2_k127_9943612_3	1168289.AJKI01000014_gene2102	1.199e-38	152.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,2FPFD@200643|Bacteroidia,3XJ9A@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
DTH2_k127_9943612_1	866536.Belba_2930	2.418e-140	450.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia	976|Bacteroidetes	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DTH2_k127_9943612_4	278957.ABEA03000094_gene4665	3.425e-34	139.0	COG0580@1|root,COG0580@2|Bacteria,46V4E@74201|Verrucomicrobia,3K87W@414999|Opitutae	414999|Opitutae	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DTH2_k127_9943612_2	1453500.AT05_02485	2.207e-99	327.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,1HWZW@117743|Flavobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
## 1805 queries scanned
## Total time (seconds): 7.9626946449279785
## Rate: 226.68 q/s