## Tue Oct 15 18:11:02 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/DTH2_bin.68.fa -m mmseqs --itype genome -o DTH2_bin.68 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/DTH2_bin.68 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DTH2_k127_10008639_2	1121904.ARBP01000003_gene6533	5.163e-05	52.0	COG0400@1|root,COG0400@2|Bacteria,4NJ8E@976|Bacteroidetes	976|Bacteroidetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10008639_0	1189612.A33Q_3219	0.0	1023.0	COG0363@1|root,COG0363@2|Bacteria,4NDUN@976|Bacteroidetes,47KPX@768503|Cytophagia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	PIG-L
DTH2_k127_10008639_1	761193.Runsl_0176	8.408e-54	201.0	COG2885@1|root,COG2885@2|Bacteria,4P1CD@976|Bacteroidetes,47U5D@768503|Cytophagia	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,OmpA,VWA
DTH2_k127_10017913_0	1211813.CAPH01000017_gene921	2.048e-127	414.0	COG1242@1|root,COG1242@2|Bacteria,4NGK6@976|Bacteroidetes,2FPR8@200643|Bacteroidia,22U4X@171550|Rikenellaceae	976|Bacteroidetes	S	Radical SAM protein	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
DTH2_k127_10017913_4	926562.Oweho_2612	1.138e-15	92.0	COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,2PBKJ@246874|Cryomorphaceae	976|Bacteroidetes	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,MAM,PKD,fn3
DTH2_k127_10017913_1	945713.IALB_1488	5.872e-33	149.0	COG3291@1|root,COG4409@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4409@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	wcoB	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix,PKD,Reprolysin_4
DTH2_k127_10017913_2	883158.HMPREF9140_00952	5.028e-22	113.0	COG1572@1|root,COG3227@1|root,COG1572@2|Bacteria,COG3227@2|Bacteria,4PHZX@976|Bacteroidetes,2FXAK@200643|Bacteroidia	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_10017913_3	485918.Cpin_1881	2.992e-16	79.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1IUPB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
DTH2_k127_10027687_1	272559.BF9343_2763	2.706e-79	274.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,2FNFB@200643|Bacteroidia,4AKKB@815|Bacteroidaceae	976|Bacteroidetes	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
DTH2_k127_10027687_5	1121920.AUAU01000011_gene232	1.454e-07	56.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	2.8.1.10	ko:K03149,ko:K03154	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiS
DTH2_k127_10027687_2	338963.Pcar_2513	7.914e-51	186.0	COG0476@1|root,COG0476@2|Bacteria,1R87S@1224|Proteobacteria,42R16@68525|delta/epsilon subdivisions,2WNMW@28221|Deltaproteobacteria,43RZK@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS-like ubiquitin	-	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF
DTH2_k127_10027687_0	1047013.AQSP01000096_gene2180	0.0	1094.0	COG2414@1|root,COG2414@2|Bacteria,2NNME@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
DTH2_k127_10027687_4	457570.Nther_0330	1.616e-16	85.0	COG2005@1|root,COG2005@2|Bacteria,1VFW6@1239|Firmicutes,24QTV@186801|Clostridia	186801|Clostridia	S	Transcriptional regulator, LysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
DTH2_k127_10027687_3	403833.Pmob_0379	1.792e-30	124.0	COG0725@1|root,COG0725@2|Bacteria,2GCV7@200918|Thermotogae	200918|Thermotogae	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K15495	ko02010,map02010	M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5	-	-	SBP_bac_11
DTH2_k127_10042654_1	760192.Halhy_0204	1.644e-57	207.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,1INMI@117747|Sphingobacteriia	976|Bacteroidetes	S	alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
DTH2_k127_10042654_0	1237149.C900_01880	4.206e-269	850.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,47KYC@768503|Cytophagia	976|Bacteroidetes	M	penicillin-binding protein 1C	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
DTH2_k127_1004518_0	709991.Odosp_2336	2.099e-98	326.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,22W0K@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_1004518_2	643867.Ftrac_3029	9.03e-64	221.0	COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,47P7P@768503|Cytophagia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DTH2_k127_1004518_1	927658.AJUM01000040_gene836	3.219e-70	238.0	COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,2FRY7@200643|Bacteroidia,3XK29@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S12/S23	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DTH2_k127_10063984_0	1408473.JHXO01000008_gene2881	2.899e-74	258.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,2FQ12@200643|Bacteroidia	976|Bacteroidetes	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
DTH2_k127_10063984_2	1168034.FH5T_11500	5.364e-50	200.0	COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,2FNYT@200643|Bacteroidia	976|Bacteroidetes	H	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Porin_10
DTH2_k127_10063984_1	1347393.HG726020_gene923	2.155e-66	231.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,2FMX8@200643|Bacteroidia,4AM3P@815|Bacteroidaceae	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH2_k127_10077463_0	1237149.C900_03053	1.893e-166	530.0	COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,47NZ3@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_10077463_3	240015.ACP_3060	1.032e-19	91.0	COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria,2JK31@204432|Acidobacteriia	204432|Acidobacteriia	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
DTH2_k127_10077463_2	1122931.AUAE01000030_gene867	4.27e-24	105.0	COG0375@1|root,COG0375@2|Bacteria,4NWR5@976|Bacteroidetes,2FV7V@200643|Bacteroidia,22YT9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
DTH2_k127_10077463_4	1385935.N836_35415	6.646e-19	98.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
DTH2_k127_10077463_5	745718.JADT01000017_gene1057	4.156e-08	66.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	fpp1	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
DTH2_k127_10077463_1	1408433.JHXV01000014_gene3638	2.256e-28	132.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,4NHY5@976|Bacteroidetes,1HZI3@117743|Flavobacteriia	976|Bacteroidetes	JM	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,fn3
DTH2_k127_101459_0	1121129.KB903359_gene2505	1.016e-51	184.0	COG2920@1|root,COG2920@2|Bacteria,4NSKM@976|Bacteroidetes,2FVZW@200643|Bacteroidia	976|Bacteroidetes	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
DTH2_k127_101459_2	8083.ENSXMAP00000014790	4.555e-07	58.0	KOG1207@1|root,KOG1207@2759|Eukaryota,39RC8@33154|Opisthokonta,3BENY@33208|Metazoa,3CXY6@33213|Bilateria,482AT@7711|Chordata,48UYP@7742|Vertebrata,49QKH@7898|Actinopterygii	33208|Metazoa	Q	L-xylulose reductase	DCXR	GO:0003674,GO:0003824,GO:0004090,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005874,GO:0005881,GO:0005886,GO:0005902,GO:0005903,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006006,GO:0006063,GO:0006064,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009987,GO:0015630,GO:0016020,GO:0016043,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016655,GO:0019318,GO:0019321,GO:0019323,GO:0019362,GO:0019585,GO:0019637,GO:0019640,GO:0019752,GO:0022607,GO:0032787,GO:0034641,GO:0042802,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0046365,GO:0046395,GO:0046483,GO:0046496,GO:0050038,GO:0051167,GO:0051186,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072329,GO:0072524,GO:0090407,GO:0098858,GO:0098862,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:1901135,GO:1901137,GO:1901159,GO:1901360,GO:1901564,GO:1901575,GO:1901576	1.1.1.10	ko:K03331	ko00040,ko01100,map00040,map01100	M00014	R01904	RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
DTH2_k127_1022124_1	314230.DSM3645_08111	1.171e-19	104.0	COG4932@1|root,COG4932@2|Bacteria,2IYDU@203682|Planctomycetes	203682|Planctomycetes	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
DTH2_k127_1022124_2	215803.DB30_8545	4.908e-07	63.0	COG3568@1|root,COG3568@2|Bacteria,1N2ZJ@1224|Proteobacteria,42WUR@68525|delta/epsilon subdivisions,2WSUA@28221|Deltaproteobacteria,2YUA6@29|Myxococcales	28221|Deltaproteobacteria	PQ	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,LTD
DTH2_k127_1022124_0	670487.Ocepr_1481	1.158e-59	228.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1043290_0	1313301.AUGC01000014_gene2473	1.066e-70	244.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein assembly complex, YaeT protein	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
DTH2_k127_1043290_1	485918.Cpin_1053	7.458e-50	188.0	COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,1IS3M@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_1043290_2	929556.Solca_0564	5.734e-33	134.0	COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,1ITN8@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH2_k127_1046958_2	445970.ALIPUT_01678	1.253e-41	154.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,2FN2D@200643|Bacteroidia,22U87@171550|Rikenellaceae	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH2_k127_1046958_0	1227739.Hsw_2017	1.391e-136	458.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47JW1@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_1046958_1	760192.Halhy_3997	1.277e-58	211.0	COG1196@1|root,COG3206@1|root,COG1196@2|Bacteria,COG3206@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
DTH2_k127_1051686_1	1123508.JH636439_gene1132	2.005e-20	96.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
DTH2_k127_1051686_0	1317122.ATO12_10500	7.275e-59	213.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1I0QN@117743|Flavobacteriia,2YJJY@290174|Aquimarina	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_1051686_2	641524.ADICYQ_4129	2.971e-08	64.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,47KZN@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,TPR_10,TPR_12,TPR_7,TPR_8
DTH2_k127_1060149_9	1453500.AT05_05120	2.402e-48	175.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia	976|Bacteroidetes	V	Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_1060149_6	1121373.KB903630_gene263	1.88e-66	234.0	COG1225@1|root,COG1225@2|Bacteria,4NXEC@976|Bacteroidetes	976|Bacteroidetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1060149_7	468059.AUHA01000002_gene623	1.192e-64	224.0	COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,1IS32@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DTH2_k127_1060149_8	908937.Prede_1148	7.785e-51	183.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DTH2_k127_1060149_4	1168289.AJKI01000040_gene3150	1.415e-103	344.0	COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,3XIMG@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S2	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DTH2_k127_1060149_5	1123057.P872_03765	3.793e-95	320.0	COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,47M4X@768503|Cytophagia	976|Bacteroidetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DTH2_k127_1060149_11	1501391.LG35_08880	3.584e-37	145.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,2FN46@200643|Bacteroidia	976|Bacteroidetes	S	YqeY-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
DTH2_k127_1060149_1	929556.Solca_2734	5.414e-148	486.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1IR5B@117747|Sphingobacteriia	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DTH2_k127_1060149_0	1408433.JHXV01000032_gene1130	7.836e-172	549.0	COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,1HY6Y@117743|Flavobacteriia,2PA5T@246874|Cryomorphaceae	976|Bacteroidetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DTH2_k127_1060149_10	485917.Phep_3324	8.581e-47	178.0	COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,1IX3I@117747|Sphingobacteriia	976|Bacteroidetes	D	Cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ
DTH2_k127_1060149_2	1122176.KB903576_gene4961	2.905e-136	447.0	COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,1INTF@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_1060149_3	313606.M23134_06301	4.331e-116	384.0	COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DTH2_k127_1075449_4	1121930.AQXG01000002_gene2151	1.858e-11	76.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1075449_3	497964.CfE428DRAFT_0440	6.803e-15	87.0	COG1361@1|root,COG1404@1|root,COG1520@1|root,COG3055@1|root,COG5184@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG1520@2|Bacteria,COG3055@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	DUF11,Kelch_4,SLH,SdrD_B
DTH2_k127_1075449_6	1396141.BATP01000060_gene4588	5.19e-06	49.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_1075449_5	1121930.AQXG01000005_gene601	1.731e-09	71.0	COG1404@1|root,COG1404@2|Bacteria,4NVH2@976|Bacteroidetes,1IURU@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1075449_2	1121904.ARBP01000011_gene1396	4.546e-18	99.0	COG1404@1|root,COG1572@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_1075449_0	485918.Cpin_3102	2.09e-62	221.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_1075449_1	485918.Cpin_3101	4.737e-46	175.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NPAJ@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator three Y	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Reg_prop,Y_Y_Y
DTH2_k127_1076263_2	1123234.AUKI01000020_gene750	6.381e-20	91.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1HWSS@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DTH2_k127_1076263_1	1408473.JHXO01000013_gene528	8.411e-77	267.0	28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,2FP92@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4835
DTH2_k127_1076263_0	762903.Pedsa_0345	4.62e-144	476.0	COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,1IQ2B@117747|Sphingobacteriia	976|Bacteroidetes	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
DTH2_k127_1094871_0	880073.Calab_0645	1.908e-268	845.0	COG3537@1|root,COG3537@2|Bacteria,2NQQ0@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
DTH2_k127_1094871_1	1408473.JHXO01000004_gene195	3.09e-125	408.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_1100213_1	929562.Emtol_3159	5.418e-48	189.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_1100213_0	1185876.BN8_01054	7.053e-66	246.0	COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1110163_10	1250005.PHEL85_0334	4.687e-21	100.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,1HYD6@117743|Flavobacteriia,3VX03@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1110163_11	865937.Gilli_0491	1.639e-11	72.0	2BAFY@1|root,323WE@2|Bacteria,4NQ3E@976|Bacteroidetes,1I30F@117743|Flavobacteriia,2P6UY@244698|Gillisia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1110163_8	743722.Sph21_1087	3.154e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,1ISGD@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM RNA polymerase sigma factor 70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_1110163_6	1168289.AJKI01000002_gene2384	1.266e-65	234.0	COG0697@1|root,COG0697@2|Bacteria,4NNBQ@976|Bacteroidetes,2FMN9@200643|Bacteroidia,3XJBC@558415|Marinilabiliaceae	976|Bacteroidetes	EG	EamA-like transporter family	eamA	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_1110163_2	1121920.AUAU01000004_gene751	5.627e-117	387.0	COG1748@1|root,COG1748@2|Bacteria,3Y84N@57723|Acidobacteria	57723|Acidobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DTH2_k127_1110163_1	714943.Mucpa_4381	8.413e-141	457.0	COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_1110163_9	471854.Dfer_3917	7.573e-39	149.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,47R7Q@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH2_k127_1110163_3	404589.Anae109_0837	5.911e-79	269.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2YUHQ@29|Myxococcales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
DTH2_k127_1110163_5	1122226.AUHX01000008_gene1391	1.24e-72	255.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,1HYCJ@117743|Flavobacteriia	976|Bacteroidetes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_1110163_7	1232410.KI421421_gene3694	5.875e-60	215.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
DTH2_k127_1110163_4	96561.Dole_2121	3.388e-78	272.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,2MI2C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DTH2_k127_1110163_0	929562.Emtol_2015	1.247e-184	599.0	COG1262@1|root,COG1262@2|Bacteria,4NJRT@976|Bacteroidetes,47TU9@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_1124039_0	1168034.FH5T_09635	3.852e-107	351.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_1124039_1	1408433.JHXV01000004_gene3388	1.569e-73	264.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,1I54C@117743|Flavobacteriia,2PAIC@246874|Cryomorphaceae	976|Bacteroidetes	Q	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_1124626_1	1047013.AQSP01000142_gene241	1.134e-232	726.0	COG0252@1|root,COG0252@2|Bacteria,2NPMK@2323|unclassified Bacteria	2|Bacteria	EJ	Asparaginase	ansA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DTH2_k127_1124626_0	1047013.AQSP01000142_gene242	1.507e-282	882.0	COG2511@1|root,COG2511@2|Bacteria	2|Bacteria	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
DTH2_k127_1124626_2	118168.MC7420_5093	8.979e-15	81.0	2EP6P@1|root,33GTE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1125325_0	468059.AUHA01000002_gene1366	4.648e-118	394.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,1IRGW@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
DTH2_k127_1125325_1	762903.Pedsa_1757	8.015e-73	252.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,1IRWM@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_1127846_1	1356852.N008_12920	2.035e-33	133.0	COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,47QM5@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
DTH2_k127_1127846_0	1408473.JHXO01000001_gene2330	1.548e-164	527.0	COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,2FN2D@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH2_k127_1135917_1	1304872.JAGC01000007_gene2252	1.295e-75	263.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,2M8R7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_1135917_0	1408473.JHXO01000011_gene3116	1.056e-144	465.0	COG3938@1|root,COG3938@2|Bacteria,4NJMD@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the proline racemase family	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
DTH2_k127_1135917_2	196367.JNFG01000006_gene6917	2.604e-07	52.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,2VMCV@28216|Betaproteobacteria,1K2IS@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
DTH2_k127_1160526_2	1046627.BZARG_1761	6.825e-22	100.0	2F4GJ@1|root,33X6I@2|Bacteria,4P3KU@976|Bacteroidetes,1I98P@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1160526_3	880071.Fleli_3258	1.38e-12	74.0	29118@1|root,2ZNNU@2|Bacteria,4P91J@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1160526_0	760192.Halhy_3780	7.851e-97	332.0	COG4249@1|root,COG4249@2|Bacteria,4NS33@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
DTH2_k127_1160526_1	269797.Mbar_A1359	6.178e-60	210.0	arCOG05193@1|root,arCOG05193@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1176433_0	1168034.FH5T_01625	1.113e-181	574.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
DTH2_k127_1176433_1	1168034.FH5T_01620	1.411e-30	124.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H,Response_reg
DTH2_k127_1176818_1	457424.BFAG_01931	8.566e-11	67.0	COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,4AN81@815|Bacteroidaceae	976|Bacteroidetes	J	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	smtA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS
DTH2_k127_1176818_0	335543.Sfum_1332	1.329e-130	432.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,42SZH@68525|delta/epsilon subdivisions,2WPX7@28221|Deltaproteobacteria,2MQHU@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
DTH2_k127_1219483_2	1356852.N008_15300	8.091e-05	54.0	COG2356@1|root,COG2356@2|Bacteria,4P4HU@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1219483_0	743722.Sph21_0509	3.983e-43	168.0	2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1IRTQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
DTH2_k127_1219483_3	929556.Solca_0738	0.0002316	45.0	COG3291@1|root,COG3291@2|Bacteria,4PHZU@976|Bacteroidetes,1IWHN@117747|Sphingobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_1219483_1	880071.Fleli_2447	2.039e-05	56.0	COG2203@1|root,COG2208@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3292@2|Bacteria,4NK8Q@976|Bacteroidetes,47YH5@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HisKA_2,Reg_prop,SpoIIE,Y_Y_Y
DTH2_k127_123448_1	485918.Cpin_0489	8.508e-138	447.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1IPH9@117747|Sphingobacteriia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
DTH2_k127_123448_0	1168034.FH5T_08670	1.829e-259	805.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DTH2_k127_125755_0	313606.M23134_00640	1.217e-257	839.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DTH2_k127_125755_1	1408473.JHXO01000011_gene3028	7.336e-184	595.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,2FMIV@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DTH2_k127_1267478_1	929556.Solca_2879	7.4e-134	432.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1IP0Q@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_1267478_0	1121129.KB903370_gene139	5.921e-151	483.0	COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,2FMMT@200643|Bacteroidia,22VZH@171551|Porphyromonadaceae	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DTH2_k127_1267478_7	1408813.AYMG01000023_gene2022	4.851e-12	66.0	2AC5I@1|root,311PY@2|Bacteria,4PGIV@976|Bacteroidetes,1ITTN@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4295
DTH2_k127_1267478_5	1237149.C900_01752	9.897e-26	108.0	COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,47S6V@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DTH2_k127_1267478_2	468059.AUHA01000003_gene1799	1.584e-122	399.0	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH2_k127_1267478_4	880073.Calab_0369	4.865e-35	137.0	2CCSR@1|root,32RWC@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_1267478_6	926549.KI421517_gene1036	1.218e-24	108.0	2DZN5@1|root,33CRM@2|Bacteria,4NZFZ@976|Bacteroidetes,47T7Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1267478_3	742725.HMPREF9450_02244	2.192e-38	145.0	COG4221@1|root,COG4221@2|Bacteria,4PKGY@976|Bacteroidetes,2FSDE@200643|Bacteroidia,22U7X@171550|Rikenellaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_1340809_0	1123277.KB893174_gene5927	5.533e-134	466.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
DTH2_k127_1340809_1	760192.Halhy_0635	1.767e-67	237.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1J04F@117747|Sphingobacteriia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_1343787_3	1120963.KB894491_gene620	1.199e-18	99.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,DUF5013,Flg_new,TIG
DTH2_k127_1343787_4	7739.XP_002598233.1	2.601e-11	76.0	KOG3714@1|root,KOG3714@2759|Eukaryota,39NJ4@33154|Opisthokonta	2759|Eukaryota	O	Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein.	-	-	3.4.24.19	ko:K05502	-	-	-	-	ko00000,ko01000,ko01002,ko04052	-	-	-	Astacin,CUB
DTH2_k127_1343787_0	1408433.JHXV01000004_gene3405	2.462e-134	437.0	COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,2PBBH@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
DTH2_k127_1343787_2	886379.AEWI01000028_gene233	1.889e-40	153.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia,3XK3U@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S6	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DTH2_k127_1343787_1	926551.KB900707_gene638	1.473e-42	156.0	COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1I2TD@117743|Flavobacteriia,1ES59@1016|Capnocytophaga	976|Bacteroidetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DTH2_k127_1371898_3	203119.Cthe_2754	3.441e-69	242.0	COG0491@1|root,COG0491@2|Bacteria,1U7GJ@1239|Firmicutes,24GHC@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_1371898_1	1499967.BAYZ01000100_gene3468	2.28e-104	344.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH2_k127_1371898_2	1237149.C900_05283	6.12e-71	264.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,47P48@768503|Cytophagia	976|Bacteroidetes	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_10,TPR_12,TPR_7,TPR_8
DTH2_k127_1371898_0	1469557.JSWF01000025_gene1352	0.0	1089.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,1HZ7E@117743|Flavobacteriia	976|Bacteroidetes	EU	peptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DTH2_k127_1371898_5	1122225.AULQ01000006_gene1161	1.765e-10	73.0	COG5295@1|root,COG5295@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1371898_4	526227.Mesil_3344	5.547e-22	110.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	yeeJ	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DUF5122,Peptidase_S74,YadA_head,YadA_stalk
DTH2_k127_1373196_3	999419.HMPREF1077_02991	1.817e-81	281.0	COG0068@1|root,COG0068@2|Bacteria,4NIZ1@976|Bacteroidetes,2FRRN@200643|Bacteroidia,22X9I@171551|Porphyromonadaceae	976|Bacteroidetes	O	Acylphosphatase	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
DTH2_k127_1373196_5	1336243.JAEA01000001_gene1852	1.075e-29	123.0	COG4319@1|root,COG4319@2|Bacteria,1R2GQ@1224|Proteobacteria,2TZK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_1373196_0	269799.Gmet_0117	9.001e-130	423.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,43U45@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
DTH2_k127_1373196_1	552811.Dehly_1413	6.052e-115	379.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,34CYH@301297|Dehalococcoidia	301297|Dehalococcoidia	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DTH2_k127_1373196_2	880073.Calab_2998	9.686e-96	320.0	COG0378@1|root,COG0378@2|Bacteria,2NQNR@2323|unclassified Bacteria	2|Bacteria	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
DTH2_k127_1407204_0	926549.KI421517_gene1872	1.798e-89	317.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
DTH2_k127_1407204_1	926562.Oweho_1769	2.6e-86	296.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_1407304_3	574087.Acear_1693	1.832e-23	109.0	COG2834@1|root,COG2834@2|Bacteria,1V6F3@1239|Firmicutes,24MGP@186801|Clostridia,3WAQP@53433|Halanaerobiales	186801|Clostridia	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
DTH2_k127_1407304_0	203275.BFO_3188	3.995e-119	411.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,2FRXV@200643|Bacteroidia,231G2@171551|Porphyromonadaceae	976|Bacteroidetes	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH2_k127_1407304_1	1341181.FLJC2902T_10670	2.191e-75	259.0	COG2085@1|root,COG2085@2|Bacteria,4NPSZ@976|Bacteroidetes,1ICXS@117743|Flavobacteriia,2NVZG@237|Flavobacterium	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
DTH2_k127_1407304_5	509191.AEDB02000067_gene894	4.124e-13	78.0	29H1X@1|root,303ZJ@2|Bacteria,1VZGD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1407304_2	743722.Sph21_4822	2.692e-29	121.0	2E3WH@1|root,32YTP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1407304_4	351160.RCIX1527	1.467e-21	97.0	COG1476@1|root,arCOG01864@2157|Archaea,2Y089@28890|Euryarchaeota,2NA1I@224756|Methanomicrobia	224756|Methanomicrobia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
DTH2_k127_1419062_5	1123008.KB905715_gene3639	1.257e-43	163.0	COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,2FM8N@200643|Bacteroidia,22VVB@171551|Porphyromonadaceae	976|Bacteroidetes	C	In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
DTH2_k127_1419062_3	880073.Calab_1424	2.603e-123	405.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9
DTH2_k127_1419062_6	880073.Calab_1425	9.304e-32	132.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
DTH2_k127_1419062_2	880073.Calab_1426	1.449e-224	713.0	COG4191@1|root,COG4624@1|root,COG4191@2|Bacteria,COG4624@2|Bacteria,2NP4X@2323|unclassified Bacteria	2|Bacteria	C	Putative Fe-S cluster	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,HAMP,HATPase_c,HTH_8,HisKA,PAS_9,Sigma54_activat
DTH2_k127_1419062_1	880073.Calab_1427	3.265e-226	714.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,2NNXH@2323|unclassified Bacteria	2|Bacteria	C	Iron hydrogenase small subunit	-	-	1.12.1.3,1.17.1.9,1.6.5.3	ko:K00123,ko:K00336,ko:K18332	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3,Pyr_redox_2
DTH2_k127_1419062_0	880073.Calab_1428	2.868e-274	857.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	hoxF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K05587,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
DTH2_k127_1419062_4	880073.Calab_1429	7.124e-50	182.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.12.1.4,1.6.5.3	ko:K00334,ko:K17999	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
DTH2_k127_1452253_3	1168034.FH5T_12180	9.161e-06	49.0	COG4585@1|root,COG4585@2|Bacteria,4NSJY@976|Bacteroidetes,2FQSP@200643|Bacteroidia	976|Bacteroidetes	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
DTH2_k127_1452253_1	869213.JCM21142_41883	1.69e-26	120.0	COG0666@1|root,COG4704@1|root,COG0666@2|Bacteria,COG4704@2|Bacteria,4NUMP@976|Bacteroidetes,47SYD@768503|Cytophagia	976|Bacteroidetes	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Fib_succ_major
DTH2_k127_1452253_2	1121286.AUMT01000003_gene2160	1.862e-11	74.0	2DVW2@1|root,33XF7@2|Bacteria,4PMYR@976|Bacteroidetes,1IK13@117743|Flavobacteriia,3ZSIX@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1452253_4	236814.IX39_02625	0.0005927	51.0	COG4886@1|root,COG4886@2|Bacteria,4NHYW@976|Bacteroidetes,1HZU3@117743|Flavobacteriia	976|Bacteroidetes	C	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1452253_0	459349.CLOAM0193	7.744e-33	141.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_4,LRR_6,LRR_8,Roc
DTH2_k127_1471136_4	1121094.KB894644_gene2110	3.088e-17	83.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,2FP9S@200643|Bacteroidia,4AMYE@815|Bacteroidaceae	976|Bacteroidetes	S	Endonuclease Exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_1471136_2	886379.AEWI01000008_gene679	1.418e-58	212.0	COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,2FMIT@200643|Bacteroidia,3XJZS@558415|Marinilabiliaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_1471136_3	468059.AUHA01000002_gene15	5.814e-51	193.0	COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,1ISN7@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA uptake protein and related DNA-binding	comEA	-	-	-	-	-	-	-	-	-	-	-	HHH_3
DTH2_k127_1471136_0	742767.HMPREF9456_01255	2.992e-188	600.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,2FPUV@200643|Bacteroidia,22WHW@171551|Porphyromonadaceae	976|Bacteroidetes	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
DTH2_k127_1471136_1	1519464.HY22_09440	3.837e-165	533.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH2_k127_1474326_0	927658.AJUM01000022_gene1286	6.763e-226	715.0	COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,3XJQF@558415|Marinilabiliaceae	976|Bacteroidetes	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH2_k127_1474326_1	1120999.JONM01000010_gene4084	4.941e-47	173.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,2VMCV@28216|Betaproteobacteria,2KSDG@206351|Neisseriales	206351|Neisseriales	P	CutC family	-	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
DTH2_k127_1490126_0	1227739.Hsw_1699	2.423e-94	315.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DTH2_k127_1490126_1	1168034.FH5T_06945	7.787e-82	279.0	COG2518@1|root,COG2518@2|Bacteria,4NMTP@976|Bacteroidetes,2FXTG@200643|Bacteroidia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DTH2_k127_1490126_2	45351.EDO26080	2.617e-52	186.0	COG1131@1|root,KOG0061@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
DTH2_k127_1494209_2	1191523.MROS_1152	1.634e-27	113.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH2_k127_1494209_0	1268240.ATFI01000005_gene4762	6.284e-137	442.0	COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,2FMV7@200643|Bacteroidia,4AN1P@815|Bacteroidaceae	976|Bacteroidetes	M	involved in cell wall biogenesis	arnC	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_1494209_3	504472.Slin_6626	1.123e-16	87.0	2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,47QS1@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
DTH2_k127_1494209_1	391596.PBAL39_19754	1.259e-82	279.0	COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1IQWM@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
DTH2_k127_1499389_8	700598.Niako_4283	2.932e-17	94.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_1499389_7	1004149.AFOE01000028_gene1802	3.383e-28	128.0	COG1044@1|root,COG3979@1|root,COG1044@2|Bacteria,COG3979@2|Bacteria,4PNZT@976|Bacteroidetes,1IKCC@117743|Flavobacteriia	976|Bacteroidetes	M	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1499389_3	313606.M23134_07726	1.332e-121	425.0	COG0296@1|root,COG1372@1|root,COG1404@1|root,COG4447@1|root,COG0296@2|Bacteria,COG1372@2|Bacteria,COG1404@2|Bacteria,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
DTH2_k127_1499389_6	1227276.HMPREF9148_00831	4.107e-49	184.0	COG1028@1|root,COG1028@2|Bacteria,4NN4M@976|Bacteroidetes,2FS25@200643|Bacteroidia	976|Bacteroidetes	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH2_k127_1499389_4	1506583.JQJY01000005_gene2364	5.509e-104	348.0	COG0332@1|root,COG0332@2|Bacteria,4NFMX@976|Bacteroidetes,1IIN6@117743|Flavobacteriia,2NV2R@237|Flavobacterium	976|Bacteroidetes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_1499389_9	1410613.JNKF01000012_gene1489	3.327e-08	58.0	COG0236@1|root,COG0236@2|Bacteria,4NWWS@976|Bacteroidetes,2FUXS@200643|Bacteroidia	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH2_k127_1499389_1	373903.Hore_13580	4.072e-158	512.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH2_k127_1499389_2	373903.Hore_13580	5.391e-149	484.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH2_k127_1499389_0	272123.Anacy_1299	4.453e-189	612.0	COG0318@1|root,COG3321@1|root,COG4221@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1FZXE@1117|Cyanobacteria,1HJCN@1161|Nostocales	1117|Cyanobacteria	IQ	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Aminotran_1_2,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
DTH2_k127_1499389_5	1227739.Hsw_1402	1.084e-53	216.0	COG1520@1|root,COG3420@1|root,COG1520@2|Bacteria,COG3420@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_1501929_2	1121373.KB903662_gene253	3.175e-19	100.0	COG5492@1|root,COG5492@2|Bacteria,4PKMF@976|Bacteroidetes,47QU9@768503|Cytophagia	976|Bacteroidetes	N	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1501929_0	1408473.JHXO01000006_gene1342	7.661e-170	544.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,2G334@200643|Bacteroidia	976|Bacteroidetes	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
DTH2_k127_1501929_1	926562.Oweho_1032	1.95e-23	115.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2PAQJ@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_1503585_0	1168289.AJKI01000030_gene1180	4.198e-131	424.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,3XIVK@558415|Marinilabiliaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DTH2_k127_1503585_1	742726.HMPREF9448_01786	7.739e-73	247.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia,22W4A@171551|Porphyromonadaceae	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DTH2_k127_1512344_0	1168034.FH5T_18135	1.109e-255	797.0	COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
DTH2_k127_1512344_1	1121898.Q766_20530	7.634e-185	583.0	COG1075@1|root,COG1075@2|Bacteria,4NFSV@976|Bacteroidetes,1HY8D@117743|Flavobacteriia,2NYPJ@237|Flavobacterium	976|Bacteroidetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DTH2_k127_152055_4	744985.HIMB59_00010460	2.346e-06	54.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2UCHU@28211|Alphaproteobacteria,4BQI6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_152055_2	1443665.JACA01000001_gene3021	3.081e-36	148.0	2BVJX@1|root,32QXQ@2|Bacteria,4NRNJ@976|Bacteroidetes,1I3JX@117743|Flavobacteriia,2YH8U@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_152055_1	153721.MYP_3097	1.36e-63	239.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,47Q0J@768503|Cytophagia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DTH2_k127_152055_0	1121904.ARBP01000015_gene161	2.696e-94	328.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_152055_3	604354.TSIB_1140	4.673e-27	119.0	COG1514@1|root,arCOG01736@2157|Archaea,2XZ2M@28890|Euryarchaeota,242VR@183968|Thermococci	183968|Thermococci	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DTH2_k127_1533139_2	1168034.FH5T_03525	1.086e-62	221.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_1533139_0	1202532.FF52_06725	3.361e-124	405.0	COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia,2NS6V@237|Flavobacterium	976|Bacteroidetes	I	glucosamine N-acyltransferase	lpxD1	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_1533139_1	926549.KI421517_gene1551	5.458e-78	264.0	COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,47MZS@768503|Cytophagia	976|Bacteroidetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DTH2_k127_1533139_3	153721.MYP_447	0.0001796	50.0	2DKXU@1|root,30TFF@2|Bacteria,4NPBR@976|Bacteroidetes,47T9J@768503|Cytophagia	976|Bacteroidetes	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
DTH2_k127_1558121_1	153721.MYP_4266	4.809e-64	224.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,47PQU@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
DTH2_k127_1558121_0	153721.MYP_4265	1.254e-140	456.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,47N4W@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_1558121_3	575590.HMPREF0156_01329	2.065e-29	120.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes	976|Bacteroidetes	IQ	acyl carrier protein	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_1558121_2	1137281.D778_01978	2.945e-45	171.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1I1RZ@117743|Flavobacteriia	976|Bacteroidetes	IQ	3-oxoacyl-(ACP) synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1558121_4	1267211.KI669560_gene406	3.287e-09	64.0	COG4775@1|root,COG4775@2|Bacteria,4NHNW@976|Bacteroidetes,1IQZB@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
DTH2_k127_1577121_3	1501391.LG35_09015	9.74e-59	207.0	COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,2FPT5@200643|Bacteroidia	976|Bacteroidetes	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
DTH2_k127_1577121_0	1499967.BAYZ01000045_gene2649	2.202e-190	604.0	COG0498@1|root,COG0498@2|Bacteria,2NQNZ@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase N terminus	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
DTH2_k127_1577121_2	945713.IALB_0798	2.131e-68	239.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
DTH2_k127_1577121_1	945713.IALB_0800	1.15e-121	396.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	trxB_2	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Pyr_redox_3
DTH2_k127_1644281_2	927658.AJUM01000034_gene376	2.159e-22	101.0	COG2133@1|root,COG2312@1|root,COG5563@1|root,COG2133@2|Bacteria,COG2312@2|Bacteria,COG5563@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc,LTD
DTH2_k127_1644281_0	869213.JCM21142_134703	6.69e-58	206.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,47RAN@768503|Cytophagia	976|Bacteroidetes	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_1644281_1	700598.Niako_0935	3.996e-49	181.0	COG3631@1|root,COG3631@2|Bacteria,4P470@976|Bacteroidetes	976|Bacteroidetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1649964_1	1454007.JAUG01000053_gene2496	2.898e-54	204.0	COG3408@1|root,COG3408@2|Bacteria,4NK6K@976|Bacteroidetes,1IUDA@117747|Sphingobacteriia	976|Bacteroidetes	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
DTH2_k127_1649964_2	1408473.JHXO01000009_gene3433	9.697e-14	81.0	2E9C0@1|root,333JQ@2|Bacteria,4NVAR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1649964_0	1239962.C943_01005	1.073e-79	271.0	COG1262@1|root,COG1262@2|Bacteria,4NJRT@976|Bacteroidetes,47TU9@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_1672112_1	1313421.JHBV01000013_gene3741	2.621e-97	332.0	2DBBP@1|root,2Z88Z@2|Bacteria	2|Bacteria	S	Sulfo-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_1672112_0	1313421.JHBV01000013_gene3742	4.394e-157	505.0	COG5361@1|root,COG5361@2|Bacteria	2|Bacteria	P	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
DTH2_k127_1672112_2	1499684.CCNP01000023_gene3412	3.127e-14	76.0	COG0300@1|root,COG0300@2|Bacteria,1UFSN@1239|Firmicutes,24J6C@186801|Clostridia,36QS2@31979|Clostridiaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_1681662_6	1122991.BAIZ01000020_gene1602	8.86e-06	48.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DTH2_k127_1681662_1	1121101.HMPREF1532_00707	2.881e-60	214.0	COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,2FN5J@200643|Bacteroidia,4AMC7@815|Bacteroidaceae	976|Bacteroidetes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DTH2_k127_1681662_0	1349822.NSB1T_11455	2.011e-161	513.0	COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,2FM6Z@200643|Bacteroidia,22W3F@171551|Porphyromonadaceae	976|Bacteroidetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DTH2_k127_1681662_2	743722.Sph21_2431	4.928e-47	176.0	COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,1IYG7@117747|Sphingobacteriia	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DTH2_k127_1681662_4	1236514.BAKL01000043_gene3368	4.469e-44	164.0	COG3467@1|root,COG3467@2|Bacteria,4NR88@976|Bacteroidetes,2FN3R@200643|Bacteroidia,4ANYW@815|Bacteroidaceae	976|Bacteroidetes	S	Pyridoxamine 5'-phosphate oxidase family protein	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
DTH2_k127_1681662_5	1121859.KB890754_gene1019	1.572e-31	126.0	COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia	976|Bacteroidetes	S	PFAM Membrane protein of	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DTH2_k127_1681662_3	1408473.JHXO01000007_gene843	3.461e-45	175.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,2FNGJ@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_1707814_5	1433126.BN938_2112	4.123e-23	100.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes,2FM8R@200643|Bacteroidia,22UPA@171550|Rikenellaceae	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
DTH2_k127_1707814_3	1121129.KB903368_gene689	3.766e-76	259.0	COG4657@1|root,COG4657@2|Bacteria,4NGEZ@976|Bacteroidetes,2FM9J@200643|Bacteroidia,22WWX@171551|Porphyromonadaceae	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
DTH2_k127_1707814_2	485917.Phep_3207	1.096e-85	289.0	COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,1IQ4U@117747|Sphingobacteriia	976|Bacteroidetes	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DTH2_k127_1707814_1	411477.PARMER_01030	2.825e-115	382.0	COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
DTH2_k127_1707814_0	694427.Palpr_1191	2.118e-118	391.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes,2FSCQ@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_1707814_4	866536.Belba_2708	8.879e-71	249.0	COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,47KJJ@768503|Cytophagia	976|Bacteroidetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
DTH2_k127_1708460_1	671143.DAMO_1997	5.412e-182	576.0	COG0538@1|root,COG0538@2|Bacteria,2NS4M@2323|unclassified Bacteria	2|Bacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
DTH2_k127_1708460_5	643867.Ftrac_3247	5.21e-32	129.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
DTH2_k127_1708460_4	1239415.CM001837_gene1954	1.432e-49	185.0	COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia,37DIP@326319|Dokdonia	976|Bacteroidetes	I	CDP-alcohol phosphatidyltransferase	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DTH2_k127_1708460_2	700598.Niako_7312	2.049e-118	394.0	COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,1IWHH@117747|Sphingobacteriia	976|Bacteroidetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DTH2_k127_1708460_0	1191523.MROS_1025	4.495e-187	591.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
DTH2_k127_1708460_3	1191523.MROS_1024	5.694e-55	200.0	COG2427@1|root,COG2427@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
DTH2_k127_1716104_2	398512.JQKC01000002_gene1915	1.826e-196	618.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DTH2_k127_1716104_0	395494.Galf_2806	0.0	1225.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
DTH2_k127_1716104_1	1168289.AJKI01000004_gene2986	2.673e-209	665.0	COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,2FN7R@200643|Bacteroidia,3XJIA@558415|Marinilabiliaceae	976|Bacteroidetes	K	Rho termination factor, N-terminal domain	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DTH2_k127_1716104_3	929562.Emtol_2616	4.746e-67	235.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,47JEX@768503|Cytophagia	976|Bacteroidetes	M	Mur ligase middle domain	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_1732695_0	1280947.HY30_11760	5.996e-76	263.0	COG2374@1|root,COG2374@2|Bacteria,1R5QF@1224|Proteobacteria,2U002@28211|Alphaproteobacteria,43XPD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_1732695_1	761193.Runsl_4449	7.566e-52	186.0	COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,47QN1@768503|Cytophagia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
DTH2_k127_1738279_0	397278.JOJN01000019_gene2333	2.512e-29	136.0	COG2132@1|root,COG2133@1|root,COG2982@1|root,COG3291@1|root,COG3401@1|root,COG4733@1|root,COG2132@2|Bacteria,COG2133@2|Bacteria,COG2982@2|Bacteria,COG3291@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PA14
DTH2_k127_1738512_1	1047013.AQSP01000045_gene109	1.218e-91	308.0	COG0686@1|root,COG0686@2|Bacteria,2NNTE@2323|unclassified Bacteria	2|Bacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	sdh	-	1.5.1.7,1.5.1.8,1.5.1.9	ko:K00290,ko:K14157	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_1738512_0	742725.HMPREF9450_00488	4.353e-311	961.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,22U5P@171550|Rikenellaceae	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH2_k127_1746392_0	1189612.A33Q_1470	5.755e-98	331.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47JKN@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_1746392_1	1123037.AUDE01000005_gene3177	2.363e-80	303.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF1194,DUF3616,FGE-sulfatase,VPEP,VWA_2
DTH2_k127_1749240_2	391603.FBALC1_12727	1.521e-42	165.0	COG2353@1|root,COG2353@2|Bacteria,4NMFT@976|Bacteroidetes,1I1D2@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_1749240_0	660470.Theba_2338	5.523e-52	208.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
DTH2_k127_1749240_1	1047013.AQSP01000051_gene2576	6.065e-49	198.0	COG2220@1|root,COG2220@2|Bacteria,2NRBH@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
DTH2_k127_1749240_3	468059.AUHA01000002_gene150	1.055e-26	113.0	COG4642@1|root,COG4642@2|Bacteria	2|Bacteria	S	regulation of ryanodine-sensitive calcium-release channel activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN
DTH2_k127_1791080_2	1349822.NSB1T_02210	9.126e-26	108.0	COG0586@1|root,COG0586@2|Bacteria,4NM65@976|Bacteroidetes,2G2Z4@200643|Bacteroidia,231Z4@171551|Porphyromonadaceae	976|Bacteroidetes	S	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DTH2_k127_1791080_0	869213.JCM21142_104430	3.467e-119	394.0	COG2223@1|root,COG2223@2|Bacteria,4PKPF@976|Bacteroidetes	976|Bacteroidetes	P	fosmidomycin resistance protein	fsr	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
DTH2_k127_1791080_1	709991.Odosp_1219	1.042e-44	173.0	COG0226@1|root,COG0226@2|Bacteria,4NHTF@976|Bacteroidetes,2G387@200643|Bacteroidia,22Y2F@171551|Porphyromonadaceae	976|Bacteroidetes	P	COGs COG0226 ABC-type phosphate transport system periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_181463_0	373903.Hore_13580	7.379e-149	484.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH2_k127_181463_1	269797.Mbar_A0025	1.212e-86	302.0	COG2244@1|root,arCOG02209@2157|Archaea,2XT90@28890|Euryarchaeota	28890|Euryarchaeota	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_181463_2	1121930.AQXG01000006_gene791	6.461e-16	83.0	COG0615@1|root,COG0615@2|Bacteria,4NY73@976|Bacteroidetes,1IUPI@117747|Sphingobacteriia	976|Bacteroidetes	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_184876_1	452652.KSE_03440	1.759e-21	103.0	2EABA@1|root,334FH@2|Bacteria,2HY0R@201174|Actinobacteria,2M4BX@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
DTH2_k127_184876_0	886379.AEWI01000021_gene1583	1.029e-125	411.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,3XKC7@558415|Marinilabiliaceae	976|Bacteroidetes	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
DTH2_k127_187787_1	1349822.NSB1T_06780	3.073e-166	535.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,2FNRC@200643|Bacteroidia,22X3X@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
DTH2_k127_187787_2	1121904.ARBP01000006_gene3982	1.587e-164	531.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia	976|Bacteroidetes	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DTH2_k127_187787_0	153721.MYP_3522	9.811e-280	871.0	COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,47JS9@768503|Cytophagia	976|Bacteroidetes	L	Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_187787_4	929562.Emtol_2234	5.482e-38	151.0	COG1943@1|root,COG1943@2|Bacteria,4NQGH@976|Bacteroidetes,47XTE@768503|Cytophagia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_187787_3	1121957.ATVL01000006_gene2616	1.312e-74	259.0	COG4122@1|root,COG4122@2|Bacteria,4NPJQ@976|Bacteroidetes,47WE2@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
DTH2_k127_187787_5	641524.ADICYQ_0211	4.049e-15	78.0	COG3409@1|root,COG3409@2|Bacteria,4NT07@976|Bacteroidetes	976|Bacteroidetes	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
DTH2_k127_1883244_0	1517682.HW49_03670	6.636e-198	625.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia,22WZR@171551|Porphyromonadaceae	976|Bacteroidetes	EU	peptidase	pop	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
DTH2_k127_1883244_2	1392498.JQLH01000001_gene386	6.35e-44	172.0	COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PGN4@252356|Maribacter	976|Bacteroidetes	M	Protein of unknown function (DUF3078)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3078
DTH2_k127_1883244_1	645991.Sgly_3252	5.385e-88	299.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DTH2_k127_1883244_3	385682.AFSL01000069_gene1479	3.462e-13	72.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,2FPYI@200643|Bacteroidia,3XITS@558415|Marinilabiliaceae	976|Bacteroidetes	S	Rhodanese-like domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
DTH2_k127_1884681_1	596151.DesfrDRAFT_0647	4.823e-46	177.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions,2WPI2@28221|Deltaproteobacteria,2M9VY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_10,TPR_16,TPR_19,TPR_4,TPR_8
DTH2_k127_1884681_3	1089547.KB913013_gene4077	2.925e-14	81.0	2C2G9@1|root,30TBP@2|Bacteria,4NP96@976|Bacteroidetes,47Q6N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_1884681_0	1121104.AQXH01000001_gene1542	1.454e-128	425.0	COG0793@1|root,COG0793@2|Bacteria,4NM82@976|Bacteroidetes	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N,TPR_2
DTH2_k127_1884681_2	216432.CA2559_09031	1.164e-26	117.0	COG0454@1|root,COG0456@2|Bacteria,4NHRI@976|Bacteroidetes,1I38S@117743|Flavobacteriia	976|Bacteroidetes	K	Transcriptional regulator, MarR family protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_1889958_5	1121129.KB903359_gene1095	4.198e-52	188.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,2FMSQ@200643|Bacteroidia,22WVB@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_1889958_6	1305737.JAFX01000001_gene1837	1.092e-29	121.0	2CCSR@1|root,32RSC@2|Bacteria,4NT8X@976|Bacteroidetes,47W4Z@768503|Cytophagia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_1889958_1	714943.Mucpa_4174	3.426e-150	486.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPMC@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_1889958_4	290315.Clim_2443	6.021e-59	211.0	2CAZH@1|root,2Z7RU@2|Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
DTH2_k127_1889958_0	393921.HQ45_01575	0.0	1035.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,22WBE@171551|Porphyromonadaceae	976|Bacteroidetes	C	SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_1889958_2	1121904.ARBP01000005_gene4731	1.356e-118	386.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
DTH2_k127_1889958_3	153721.MYP_1063	1.365e-98	335.0	COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,47XWD@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase III, delta' subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
DTH2_k127_1889958_7	1121012.AUKX01000040_gene3202	3.463e-07	54.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia,23G5N@178469|Arenibacter	976|Bacteroidetes	S	PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
DTH2_k127_1902604_4	1358423.N180_15950	3.453e-11	64.0	COG4775@1|root,COG4775@2|Bacteria,4NHNW@976|Bacteroidetes,1IQTG@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
DTH2_k127_1902604_0	153721.MYP_4262	2.291e-120	397.0	COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,47PEB@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_1902604_3	742727.HMPREF9447_04271	2.903e-49	179.0	COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,2FTJB@200643|Bacteroidia,4AQGM@815|Bacteroidaceae	976|Bacteroidetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH2_k127_1902604_1	926562.Oweho_0229	9.108e-94	325.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia,2PAFC@246874|Cryomorphaceae	976|Bacteroidetes	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_1902604_2	1121899.Q764_05600	7.487e-86	289.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia,2NU6F@237|Flavobacterium	976|Bacteroidetes	V	Multidrug ABC transporter ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_1938175_1	760142.Hipma_1401	4.279e-84	284.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,2M69H@213113|Desulfurellales	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_1938175_0	1168034.FH5T_13085	3.865e-120	393.0	COG1216@1|root,COG1216@2|Bacteria,4PPEY@976|Bacteroidetes,2G18V@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_1951311_9	2903.EOD27628	4.667e-42	161.0	KOG1584@1|root,KOG1584@2759|Eukaryota	2759|Eukaryota	S	sulfotransferase activity	St1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006805,GO:0006950,GO:0006952,GO:0008146,GO:0008150,GO:0008152,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016740,GO:0016782,GO:0042221,GO:0042742,GO:0043207,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0051923,GO:0070887,GO:0071466,GO:0098542	2.8.2.1,2.8.2.4	ko:K01014,ko:K01016,ko:K01025	ko00140,ko05204,map00140,map05204	-	R01242,R02350	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
DTH2_k127_1951311_6	907348.TresaDRAFT_0238	5.074e-77	260.0	COG2131@1|root,COG2131@2|Bacteria,2J6UR@203691|Spirochaetes	203691|Spirochaetes	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
DTH2_k127_1951311_7	1237149.C900_03373	8.697e-53	192.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes	976|Bacteroidetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_1951311_0	1121904.ARBP01000007_gene3064	0.0	1090.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,47KTB@768503|Cytophagia	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DTH2_k127_1951311_5	946077.W5A_02375	3.388e-81	274.0	COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1HXI6@117743|Flavobacteriia	976|Bacteroidetes	C	lipoprotein involved in nitrous oxide reduction	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
DTH2_k127_1951311_10	1121904.ARBP01000007_gene3066	1.314e-37	147.0	COG4314@1|root,COG4314@2|Bacteria,4NVVP@976|Bacteroidetes,47S32@768503|Cytophagia	976|Bacteroidetes	C	NosL	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
DTH2_k127_1951311_1	1237149.C900_03369	3.424e-151	490.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,47KEF@768503|Cytophagia	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DTH2_k127_1951311_4	1250232.JQNJ01000001_gene2745	2.835e-81	279.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1HYYD@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
DTH2_k127_1951311_3	1237149.C900_03367	2.093e-95	319.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,47KSX@768503|Cytophagia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
DTH2_k127_1951311_2	1121904.ARBP01000002_gene7211	1.071e-107	355.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
DTH2_k127_1952011_6	991.IW20_03875	2.655e-05	58.0	COG1409@1|root,COG2304@1|root,COG3204@1|root,COG3391@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2304@2|Bacteria,COG3204@2|Bacteria,COG3391@2|Bacteria,COG5337@2|Bacteria,4NVTX@976|Bacteroidetes	976|Bacteroidetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc
DTH2_k127_1952011_3	1484460.JSWG01000009_gene626	1.309e-26	126.0	COG2866@1|root,COG3291@1|root,COG4412@1|root,COG2866@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,4NI4A@976|Bacteroidetes,1I44J@117743|Flavobacteriia	976|Bacteroidetes	L	MAM domain, meprin/A5/mu	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,fn3
DTH2_k127_1952011_5	1242864.D187_000532	1.168e-14	87.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	Otg1	-	-	-	-	-	-	-	-	-	-	-	DUF2339,DUF4167
DTH2_k127_1952011_1	234267.Acid_5651	5.262e-131	429.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
DTH2_k127_1952011_2	1379698.RBG1_1C00001G0296	2.481e-79	272.0	COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	ttrB	-	-	ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4_11,Fer4_3,Fer4_7
DTH2_k127_1952011_4	234267.Acid_5653	2.152e-25	110.0	2EE9W@1|root,3384B@2|Bacteria	2|Bacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
DTH2_k127_1952011_0	1121920.AUAU01000009_gene1860	1.361e-137	447.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH2_k127_1960165_1	313606.M23134_00578	1.776e-19	99.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4PI8Y@976|Bacteroidetes,47TST@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
DTH2_k127_1960165_0	1121904.ARBP01000032_gene2024	1.829e-144	484.0	COG1629@1|root,COG4771@2|Bacteria,4NKZP@976|Bacteroidetes,47NF4@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
DTH2_k127_1974199_1	927658.AJUM01000037_gene1875	7.552e-45	177.0	28NPZ@1|root,2ZBPQ@2|Bacteria,4NN3K@976|Bacteroidetes,2FPEH@200643|Bacteroidia,3XJXJ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_1974199_0	1408473.JHXO01000001_gene2449	3.45e-99	329.0	COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,2FW6T@200643|Bacteroidia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DTH2_k127_1974513_1	694427.Palpr_2430	2.878e-98	334.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,2FNEV@200643|Bacteroidia,22WBN@171551|Porphyromonadaceae	976|Bacteroidetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_1974513_0	880073.Calab_2517	8.8e-141	456.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
DTH2_k127_2006111_0	247490.KSU1_D0367	1.222e-53	194.0	COG0463@1|root,COG0463@2|Bacteria,2IXAV@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_2006111_1	891968.Anamo_1881	2.846e-50	191.0	COG0463@1|root,COG1807@1|root,COG2246@1|root,COG0463@2|Bacteria,COG1807@2|Bacteria,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	MA20_09515	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA,PMT_2
DTH2_k127_2028992_1	468059.AUHA01000003_gene1428	3.846e-162	526.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
DTH2_k127_2028992_0	1168034.FH5T_16570	5.092e-195	613.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH2_k127_2037213_0	1183438.GKIL_2176	4.807e-39	166.0	COG1372@1|root,COG4409@1|root,COG1372@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Phage_Mu_F,RHS_repeat
DTH2_k127_2037213_1	1122179.KB890433_gene4020	4.734e-31	141.0	COG0265@1|root,COG1572@1|root,COG3209@1|root,COG0265@2|Bacteria,COG1572@2|Bacteria,COG3209@2|Bacteria,4PKT1@976|Bacteroidetes	976|Bacteroidetes	O	COG3209 Rhs family protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2
DTH2_k127_2038725_1	1168034.FH5T_05180	5.153e-100	336.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2038725_2	869213.JCM21142_269	4.121e-43	164.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH2_k127_2038725_3	1121373.KB903666_gene1246	2.697e-24	109.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,47K4U@768503|Cytophagia	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase membrane protein	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
DTH2_k127_2038725_0	1168034.FH5T_05165	1.85e-201	636.0	COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes	976|Bacteroidetes	C	Pfam Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH2_k127_2038725_4	929556.Solca_3368	5.921e-23	101.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,1IPWZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
DTH2_k127_2041517_1	926562.Oweho_3512	9.257e-99	331.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,1HXKT@117743|Flavobacteriia,2PANG@246874|Cryomorphaceae	976|Bacteroidetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
DTH2_k127_2041517_0	1123248.KB893348_gene337	4.11e-199	631.0	COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,1IPB1@117747|Sphingobacteriia	976|Bacteroidetes	J	tRNA nucleotidyltransferase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
DTH2_k127_2041517_2	1443665.JACA01000001_gene2986	6.527e-14	74.0	COG2207@1|root,COG2207@2|Bacteria,4NVT9@976|Bacteroidetes,1IM68@117743|Flavobacteriia,2YHIZ@290174|Aquimarina	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
DTH2_k127_204420_0	313606.M23134_08159	3.24e-171	554.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DTH2_k127_205711_2	1123037.AUDE01000014_gene442	1.285e-36	143.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DTH2_k127_205711_3	313606.M23134_03667	6.937e-24	115.0	28JBH@1|root,2Z967@2|Bacteria,4NNHF@976|Bacteroidetes,47PBF@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
DTH2_k127_205711_1	880073.Calab_0031	9.491e-128	419.0	COG2017@1|root,COG2017@2|Bacteria,2NQA5@2323|unclassified Bacteria	2|Bacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
DTH2_k127_205711_0	1340493.JNIF01000004_gene829	7.119e-153	495.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH2_k127_2072381_1	767817.Desgi_0851	2.563e-50	185.0	COG0725@1|root,COG0725@2|Bacteria,1V2FD@1239|Firmicutes,24CFB@186801|Clostridia,260SH@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM tungstate ABC transporter binding protein WtpA	-	-	-	ko:K15495	ko02010,map02010	M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5	-	-	SBP_bac_11
DTH2_k127_2072381_0	1168034.FH5T_01670	2.66e-179	569.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,2FQQ7@200643|Bacteroidia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.88,1.5.5.2	ko:K00128,ko:K13821	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00245,R00264,R00631,R00707,R00708,R00710,R00904,R01253,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04444,R04445,R04506,R04903,R05050,R05051,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00083,RC00186,RC00216,RC00218,RC00242,RC00255,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
DTH2_k127_2084363_1	1317122.ATO12_19590	1.263e-202	663.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2YHK8@290174|Aquimarina	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PKD
DTH2_k127_2084363_0	1223410.KN050846_gene286	0.0	1107.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_209329_1	1288963.ADIS_1784	9.095e-172	551.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,47JFD@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
DTH2_k127_209329_0	1121904.ARBP01000060_gene1915	8.747e-205	643.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_2101052_0	468059.AUHA01000004_gene2291	4.635e-138	461.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1J0JA@117747|Sphingobacteriia	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
DTH2_k127_2101052_1	1237149.C900_04890	2.744e-82	286.0	COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,47JWS@768503|Cytophagia	976|Bacteroidetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DTH2_k127_210580_2	1168289.AJKI01000023_gene1935	4.768e-19	90.0	COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
DTH2_k127_210580_1	164757.Mjls_2350	2.206e-24	115.0	2CKJ1@1|root,2Z7MP@2|Bacteria,2GUWA@201174|Actinobacteria,2386D@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_210580_0	521011.Mpal_0465	1.121e-37	141.0	COG5253@1|root,arCOG04169@2157|Archaea,2XT9A@28890|Euryarchaeota,2N9AJ@224756|Methanomicrobia	224756|Methanomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
DTH2_k127_2118663_1	452637.Oter_1159	2.418e-74	256.0	COG3867@1|root,COG3867@2|Bacteria,46VSS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycosyl hydrolase 53 domain protein	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
DTH2_k127_2118663_0	1168034.FH5T_03800	1.745e-97	325.0	COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,2FM0Q@200643|Bacteroidia	976|Bacteroidetes	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
DTH2_k127_2119665_0	1121011.AUCB01000008_gene1154	1.929e-277	865.0	COG2936@1|root,COG2936@2|Bacteria,4NHGT@976|Bacteroidetes,1HYGE@117743|Flavobacteriia,23GR0@178469|Arenibacter	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
DTH2_k127_2122237_0	880073.Calab_0034	1.262e-122	417.0	COG3408@1|root,COG3408@2|Bacteria,2NPVQ@2323|unclassified Bacteria	2|Bacteria	G	Trehalase	-	-	-	ko:K03931	-	-	-	-	ko00000	-	GH63	-	Glyco_hydro_63,Trehalase
DTH2_k127_2122237_1	1168034.FH5T_21980	3.916e-81	278.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,2FN1K@200643|Bacteroidia	976|Bacteroidetes	EU	Peptidase, S9A B C family, catalytic domain protein	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
DTH2_k127_2138933_1	643867.Ftrac_0498	1.154e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,47PQF@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
DTH2_k127_2138933_0	945713.IALB_3159	1.139e-17	100.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	AAA_15
DTH2_k127_2146543_1	497964.CfE428DRAFT_5241	4.884e-84	292.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
DTH2_k127_2146543_0	1303518.CCALI_01571	4.696e-215	685.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	He_PIG,He_PIG_assoc,Melibiase_2,Melibiase_2_C,NPCBM
DTH2_k127_2146543_2	518766.Rmar_1703	1.729e-20	103.0	COG0784@1|root,COG3292@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NK8Q@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_2158035_1	869213.JCM21142_52147	6.461e-106	351.0	COG0280@1|root,COG0280@2|Bacteria,4NJPR@976|Bacteroidetes	976|Bacteroidetes	C	phosphate butyryltransferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
DTH2_k127_2158035_0	1304284.L21TH_2281	1.977e-125	411.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,36EGP@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
DTH2_k127_2192045_3	1155718.KB891895_gene2407	4.76e-64	231.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,2I9Q1@201174|Actinobacteria	201174|Actinobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2192045_4	518766.Rmar_0295	7.565e-15	85.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_2192045_2	926551.KB900703_gene930	7.039e-102	349.0	COG2234@1|root,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
DTH2_k127_2192045_1	1506583.JQJY01000003_gene3249	7.457e-142	462.0	COG2855@1|root,COG2855@2|Bacteria,4NES6@976|Bacteroidetes,1I7Q1@117743|Flavobacteriia,2NUF2@237|Flavobacterium	976|Bacteroidetes	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
DTH2_k127_2192045_0	509635.N824_25215	1.602e-290	920.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Gal_mutarotas_2,Glyco_hydro_31,fn3
DTH2_k127_2193150_1	700598.Niako_0318	3.174e-92	310.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1INQY@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DTH2_k127_2193150_2	1235813.JCM10003_2149	2.685e-67	234.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,2FP46@200643|Bacteroidia,4AMVS@815|Bacteroidaceae	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DTH2_k127_2193150_0	385682.AFSL01000026_gene620	2.473e-102	336.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,2FM57@200643|Bacteroidia,3XKG1@558415|Marinilabiliaceae	976|Bacteroidetes	L	Uracil DNA glycosylase superfamily	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DTH2_k127_2193150_3	1453500.AT05_03175	1.874e-12	74.0	28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2210491_0	411476.BACOVA_03151	1.28e-06	62.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,2FQ2M@200643|Bacteroidia,4APCC@815|Bacteroidaceae	976|Bacteroidetes	M	Peptidase, M28 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_2244323_2	886379.AEWI01000040_gene2774	3.361e-09	68.0	COG2353@1|root,COG3210@1|root,COG5492@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,4PNR0@976|Bacteroidetes,2FNS2@200643|Bacteroidia,3XJMD@558415|Marinilabiliaceae	976|Bacteroidetes	NU	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Laminin_G_3
DTH2_k127_2244323_3	1189620.AJXL01000046_gene1337	9.502e-05	54.0	COG2866@1|root,COG2866@2|Bacteria,4PPPD@976|Bacteroidetes	976|Bacteroidetes	E	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2244323_0	1408473.JHXO01000011_gene3152	6.177e-186	617.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
DTH2_k127_2244323_1	153721.MYP_768	9.678e-13	74.0	COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,47JSU@768503|Cytophagia	976|Bacteroidetes	H	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TonB_dep_Rec
DTH2_k127_2262039_6	1184267.A11Q_50	5.057e-05	48.0	COG2901@1|root,COG2901@2|Bacteria,1QSYM@1224|Proteobacteria,437MQ@68525|delta/epsilon subdivisions,2MU5A@213481|Bdellovibrionales,2WYME@28221|Deltaproteobacteria	213481|Bdellovibrionales	KL	Site-specific DNA inversion stimulation factor	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
DTH2_k127_2262039_4	518766.Rmar_0609	4.226e-24	109.0	2FFT5@1|root,347QA@2|Bacteria,4P5W2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
DTH2_k127_2262039_2	927658.AJUM01000034_gene467	1.715e-60	224.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes,2FZAQ@200643|Bacteroidia	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
DTH2_k127_2262039_3	927658.AJUM01000034_gene466	5.937e-56	204.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
DTH2_k127_2262039_0	1191523.MROS_2744	1.593e-259	808.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01966,ko:K01969	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_2262039_1	929713.NIASO_10095	3.989e-79	271.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,1IRW8@117747|Sphingobacteriia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_2268532_2	313606.M23134_01983	1.911e-23	102.0	COG1387@1|root,COG1387@2|Bacteria,4NIJU@976|Bacteroidetes,47Q20@768503|Cytophagia	976|Bacteroidetes	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
DTH2_k127_2268532_0	1120965.AUBV01000001_gene3158	1.183e-162	517.0	COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_2268532_1	1270196.JCKI01000007_gene2421	4.876e-100	332.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,1IPMW@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DTH2_k127_2284409_1	945713.IALB_0392	8.657e-96	319.0	COG3239@1|root,COG3239@2|Bacteria	2|Bacteria	I	unsaturated fatty acid biosynthetic process	crtW	-	-	ko:K09836	ko00906,map00906	-	R05345,R07549,R07557,R07563,R07564,R07565,R07566,R07567,R07571,R07573	RC01900,RC01991	ko00000,ko00001	-	-	-	FA_desaturase
DTH2_k127_2284409_2	1408473.JHXO01000005_gene1732	1.414e-44	169.0	COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,2FV0Z@200643|Bacteroidia	976|Bacteroidetes	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
DTH2_k127_2284409_0	1408813.AYMG01000027_gene5329	2.978e-114	378.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_230828_1	991.IW20_02685	5.939e-157	501.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,1HYAD@117743|Flavobacteriia,2NSN2@237|Flavobacterium	976|Bacteroidetes	C	Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
DTH2_k127_230828_0	1408433.JHXV01000032_gene1133	6.803e-185	592.0	COG1807@1|root,COG1807@2|Bacteria,4PG9X@976|Bacteroidetes,1IMRA@117743|Flavobacteriia,2PBNI@246874|Cryomorphaceae	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_230828_2	997884.HMPREF1068_04218	4.281e-42	173.0	COG4870@1|root,COG4870@2|Bacteria,4NKEE@976|Bacteroidetes,2FRKR@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the peptidase C1 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2308590_4	714943.Mucpa_1243	2.006e-36	143.0	COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_2308590_1	927658.AJUM01000042_gene1689	4.994e-209	660.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,2FRUW@200643|Bacteroidia,3XJN9@558415|Marinilabiliaceae	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_2308590_2	1239962.C943_03492	3.098e-101	336.0	COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia	976|Bacteroidetes	I	PFAM Squalene phytoene synthase	crtB	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
DTH2_k127_2308590_3	1048983.EL17_11325	1.984e-55	201.0	arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia	976|Bacteroidetes	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2308590_0	470145.BACCOP_02443	5.134e-230	718.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AMNJ@815|Bacteroidaceae	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	GO:0005575,GO:0005623,GO:0009986,GO:0044464	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH2_k127_2308590_5	153721.MYP_3156	3.985e-19	96.0	COG0457@1|root,COG2849@1|root,COG0457@2|Bacteria,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47N8G@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_8
DTH2_k127_2321454_0	926549.KI421517_gene3052	0.0	1203.0	COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia	976|Bacteroidetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DTH2_k127_2331861_1	485918.Cpin_3102	6.332e-37	141.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_2331861_2	1191523.MROS_2643	0.000119	54.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,TIG
DTH2_k127_2331861_0	290512.Paes_0204	4.626e-38	159.0	COG1262@1|root,COG1680@1|root,COG1262@2|Bacteria,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,Fib_succ_major,TIR_2
DTH2_k127_2331861_3	694427.Palpr_2226	0.0008996	43.0	COG3656@1|root,COG3656@2|Bacteria,4NHDQ@976|Bacteroidetes,2FTSH@200643|Bacteroidia,22Y91@171551|Porphyromonadaceae	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	-
DTH2_k127_2366327_3	886379.AEWI01000035_gene3046	7.628e-55	202.0	2EE6H@1|root,33812@2|Bacteria,4NWZS@976|Bacteroidetes,2FV2X@200643|Bacteroidia,3XJQ9@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
DTH2_k127_2366327_1	1408473.JHXO01000011_gene3175	2.749e-130	427.0	COG0111@1|root,COG0111@2|Bacteria,4NGEB@976|Bacteroidetes,2FMMV@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
DTH2_k127_2366327_0	886379.AEWI01000023_gene50	1.039e-290	906.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia,3XIPI@558415|Marinilabiliaceae	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
DTH2_k127_2366327_2	1506583.JQJY01000001_gene550	8.064e-71	247.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,1HXM3@117743|Flavobacteriia,2NV5S@237|Flavobacterium	976|Bacteroidetes	P	ZIP Zinc transporter	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
DTH2_k127_2366327_5	1191523.MROS_0653	9.075e-05	51.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
DTH2_k127_2369660_3	714943.Mucpa_3247	6.193e-63	222.0	COG1556@1|root,COG1556@2|Bacteria,4NIGX@976|Bacteroidetes,1IRJ2@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
DTH2_k127_2369660_5	743722.Sph21_1305	7.311e-58	211.0	COG0575@1|root,COG0575@2|Bacteria,4PPXI@976|Bacteroidetes,1J13D@117747|Sphingobacteriia	976|Bacteroidetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DTH2_k127_2369660_6	742817.HMPREF9449_01183	2.386e-53	196.0	COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,2FMVT@200643|Bacteroidia,22W27@171551|Porphyromonadaceae	976|Bacteroidetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DTH2_k127_2369660_4	886379.AEWI01000012_gene1053	3.722e-59	210.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,2FPZE@200643|Bacteroidia,3XJMJ@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosome recycling factor	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DTH2_k127_2369660_1	1123278.KB893607_gene4618	2.453e-145	468.0	COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia	976|Bacteroidetes	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DTH2_k127_2369660_8	376686.Fjoh_1009	0.0004444	48.0	2CED8@1|root,32YZ6@2|Bacteria,4NVDS@976|Bacteroidetes,1I5AZ@117743|Flavobacteriia,2NWVN@237|Flavobacterium	976|Bacteroidetes	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
DTH2_k127_2369660_7	1168034.FH5T_03920	4.96e-09	60.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
DTH2_k127_2369660_2	742817.HMPREF9449_02566	2.058e-75	266.0	COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes	976|Bacteroidetes	F	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_2369660_0	929556.Solca_2801	2.501e-310	960.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IPRD@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
DTH2_k127_2378827_1	714943.Mucpa_4396	5.422e-64	221.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,1IPN2@117747|Sphingobacteriia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH2_k127_2378827_4	385682.AFSL01000055_gene412	0.0003759	47.0	2DI87@1|root,302BG@2|Bacteria,4PJBM@976|Bacteroidetes,2G282@200643|Bacteroidia,3XKAK@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2378827_3	1121904.ARBP01000016_gene5193	4.992e-49	179.0	COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes,47Q9W@768503|Cytophagia	976|Bacteroidetes	O	Chaperonin 10 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
DTH2_k127_2378827_2	1089547.KB913013_gene281	5.008e-50	183.0	2CBKC@1|root,32RTJ@2|Bacteria,4NTE7@976|Bacteroidetes,47PC7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2378827_0	1150600.ADIARSV_3407	8.632e-195	623.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH2_k127_2385416_2	269798.CHU_0481	4.86e-14	84.0	2C85E@1|root,30YA3@2|Bacteria,4PC1M@976|Bacteroidetes,47WP9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2385416_0	742817.HMPREF9449_01681	1.335e-294	936.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia,2326J@171551|Porphyromonadaceae	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
DTH2_k127_2385416_1	945713.IALB_2776	1.577e-95	319.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.1.1.199	ko:K03438,ko:K13292	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	LGT
DTH2_k127_2441280_1	760192.Halhy_4644	1.286e-91	310.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH2_k127_2441280_0	1189619.pgond44_05140	2.379e-128	421.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HY9H@117743|Flavobacteriia,4C3UP@83612|Psychroflexus	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_2441280_2	1167006.UWK_00117	2.98e-39	152.0	COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,4309G@68525|delta/epsilon subdivisions,2WSN0@28221|Deltaproteobacteria,2MNFM@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
DTH2_k127_2441280_3	1121004.ATVC01000005_gene1342	4.609e-12	66.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2VU3F@28216|Betaproteobacteria,2KS3Z@206351|Neisseriales	206351|Neisseriales	P	Multidrug resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
DTH2_k127_2444744_1	1120965.AUBV01000003_gene289	1.256e-27	133.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5
DTH2_k127_2444744_0	1380600.AUYN01000001_gene2340	1.342e-149	530.0	COG2304@1|root,COG3291@1|root,COG3391@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
DTH2_k127_2453801_0	1453500.AT05_06795	0.0	1022.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
DTH2_k127_2453801_1	153721.MYP_4435	1.59e-85	299.0	COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,47PGX@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_2453801_2	1191523.MROS_0111	2.432e-11	68.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DTH2_k127_2516126_0	1131812.JQMS01000001_gene1012	6.828e-51	205.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,Cadherin_3,Calx-beta,DUF4347,He_PIG,Invasin_D3,Laminin_G_3,Lectin_C,PKD,Pentaxin
DTH2_k127_2516126_1	59374.Fisuc_1605	5.269e-13	80.0	COG0406@1|root,COG4704@1|root,COG0406@2|Bacteria,COG4704@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	Fib_succ_major,His_Phos_1
DTH2_k127_2516562_1	929703.KE386491_gene2378	2.475e-29	121.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
DTH2_k127_2516562_0	1107311.Q767_12015	3.981e-140	460.0	COG2355@1|root,COG2355@2|Bacteria,4NI3V@976|Bacteroidetes,1I0XS@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
DTH2_k127_2520197_1	1168034.FH5T_05180	2.821e-16	80.0	COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes	976|Bacteroidetes	P	Quinol cytochrome c oxidoreductase	actF	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2520197_0	387092.NIS_1187	3.617e-84	294.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	ccsBA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
DTH2_k127_2521633_0	1408473.JHXO01000006_gene1080	5.906e-308	964.0	COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,2G065@200643|Bacteroidia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
DTH2_k127_2521633_1	1408473.JHXO01000006_gene1079	3.687e-55	198.0	COG4198@1|root,COG4198@2|Bacteria,4NI11@976|Bacteroidetes,2FNDZ@200643|Bacteroidia	976|Bacteroidetes	S	Susd and RagB outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like
DTH2_k127_2529975_1	1121930.AQXG01000003_gene2686	7.022e-116	383.0	COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,1J0KU@117747|Sphingobacteriia	976|Bacteroidetes	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind
DTH2_k127_2529975_0	926562.Oweho_3158	4.599e-131	426.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1HX0S@117743|Flavobacteriia,2PAI3@246874|Cryomorphaceae	976|Bacteroidetes	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
DTH2_k127_2529975_5	945713.IALB_2163	2.764e-30	138.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH2_k127_2529975_4	391587.KAOT1_06422	6.057e-37	163.0	COG2356@1|root,COG3227@1|root,COG4733@1|root,COG2356@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria,4NEGS@976|Bacteroidetes,1HWRI@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Endonuclease_1,LTD,SprB,fn3
DTH2_k127_2529975_6	1121288.AULL01000016_gene660	2.773e-15	91.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_2529975_3	1443665.JACA01000025_gene3477	1.362e-89	334.0	COG1572@1|root,COG3227@1|root,COG1572@2|Bacteria,COG3227@2|Bacteria,4NHWZ@976|Bacteroidetes,1HZTV@117743|Flavobacteriia,2YKMH@290174|Aquimarina	976|Bacteroidetes	E	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,P_proprotein,fn3
DTH2_k127_2529975_2	1123008.KB905692_gene110	1.745e-94	319.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,2FNX9@200643|Bacteroidia,22XHF@171551|Porphyromonadaceae	976|Bacteroidetes	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DTH2_k127_2538967_0	869213.JCM21142_3880	2.84e-97	325.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes	976|Bacteroidetes	E	Xaa-His dipeptidase	pepD_1	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_2538967_4	553178.CAPGI0001_0820	2.996e-08	63.0	COG2067@1|root,COG2067@2|Bacteria,4NSQ9@976|Bacteroidetes,1I4ZD@117743|Flavobacteriia,1ERT5@1016|Capnocytophaga	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2538967_1	1408473.JHXO01000011_gene3022	5.421e-94	326.0	2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,2FMDV@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_2538967_3	861299.J421_6270	5.405e-10	62.0	2DJDE@1|root,305RC@2|Bacteria,1ZV7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2538967_2	1267534.KB906755_gene4296	2.28e-76	261.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria,2JI5Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH2_k127_2540604_2	1121899.Q764_11520	1.151e-70	246.0	COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,1HWT5@117743|Flavobacteriia,2NSR6@237|Flavobacterium	976|Bacteroidetes	M	permease	lolE_1	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_2540604_1	385682.AFSL01000060_gene1823	2.195e-93	312.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,2FPGR@200643|Bacteroidia,3XJTJ@558415|Marinilabiliaceae	976|Bacteroidetes	EH	Phosphoadenosine phosphosulfate reductase family	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH2_k127_2540604_0	362418.IW19_06970	4.419e-101	333.0	COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia,2NSA2@237|Flavobacterium	976|Bacteroidetes	M	Peptidoglycan synthetase	mpl	-	6.3.2.45,6.3.2.8	ko:K01924,ko:K02558	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_2542648_1	1121098.HMPREF1534_01564	9.41e-45	169.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,4APBK@815|Bacteroidaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
DTH2_k127_2542648_2	1223410.KN050846_gene146	3.302e-06	59.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3_5,CHU_C,Calx-beta,NHL,PA14,VCBS
DTH2_k127_2542648_0	616991.JPOO01000003_gene235	4.167e-48	183.0	COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,1HY33@117743|Flavobacteriia,23HTN@178469|Arenibacter	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosC,MetallophosN
DTH2_k127_2566163_0	385682.AFSL01000100_gene21	0.0	1856.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,3XJJC@558415|Marinilabiliaceae	976|Bacteroidetes	K	RNA polymerase I subunit A N-terminus	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DTH2_k127_2566163_6	762903.Pedsa_2262	1.37e-33	133.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
DTH2_k127_2566163_10	1122605.KB893625_gene2304	0.0006961	53.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
DTH2_k127_2566163_3	1121904.ARBP01000009_gene4328	8.233e-67	253.0	COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia	976|Bacteroidetes	KT	PFAM Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
DTH2_k127_2566163_5	1121904.ARBP01000013_gene353	5.775e-38	147.0	COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,47R7N@768503|Cytophagia	976|Bacteroidetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
DTH2_k127_2566163_1	1454007.JAUG01000087_gene3918	1.539e-212	682.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,1IQ2F@117747|Sphingobacteriia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
DTH2_k127_2566163_2	1033732.CAHI01000010_gene1852	4.073e-141	455.0	COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,2FPNC@200643|Bacteroidia,22V76@171550|Rikenellaceae	976|Bacteroidetes	S	SigmaW regulon antibacterial	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
DTH2_k127_2566163_8	1168034.FH5T_13775	2.764e-29	122.0	COG1030@1|root,COG1030@2|Bacteria,4NW09@976|Bacteroidetes,2FRYF@200643|Bacteroidia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
DTH2_k127_2566163_9	883096.HMPREF9699_01838	1.022e-21	97.0	COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1I3WR@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the ClpS family	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
DTH2_k127_2566163_4	1237149.C900_02511	8.329e-50	185.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_2566163_7	1168034.FH5T_19045	2.722e-32	127.0	COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,2FU46@200643|Bacteroidia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
DTH2_k127_2616707_0	929562.Emtol_0623	1.769e-48	181.0	COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia	976|Bacteroidetes	H	PFAM Biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
DTH2_k127_2616707_1	452471.Aasi_0233	3.232e-36	141.0	COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia	976|Bacteroidetes	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
DTH2_k127_2616707_2	984262.SGRA_1334	5.169e-27	117.0	COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,1IQ2Z@117747|Sphingobacteriia	976|Bacteroidetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
DTH2_k127_2617875_10	1121889.AUDM01000017_gene2162	7.08e-19	101.0	COG5295@1|root,COG5295@2|Bacteria,4NN21@976|Bacteroidetes,1I1UJ@117743|Flavobacteriia,2NUBX@237|Flavobacterium	976|Bacteroidetes	UW	arginyl-trna synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2617875_11	1268622.AVS7_04161	6.356e-12	78.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria	1224|Proteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_2617875_9	1313421.JHBV01000016_gene5427	2.535e-31	140.0	COG3210@1|root,COG3210@2|Bacteria,4P53W@976|Bacteroidetes	976|Bacteroidetes	U	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH2_k127_2617875_5	1408473.JHXO01000005_gene1519	3.039e-123	402.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,2FN4I@200643|Bacteroidia	976|Bacteroidetes	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
DTH2_k127_2617875_7	266762.HQ36_05110	1.62e-53	193.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,2FSTK@200643|Bacteroidia,22YUQ@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_2617875_4	1453500.AT05_00420	1.165e-126	424.0	2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,1HYX2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2617875_8	1453500.AT05_05495	1.976e-53	198.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
DTH2_k127_2617875_0	742817.HMPREF9449_02589	0.0	1151.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22WFX@171551|Porphyromonadaceae	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
DTH2_k127_2617875_2	886379.AEWI01000047_gene3076	9.855e-204	651.0	COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,3XJ4V@558415|Marinilabiliaceae	976|Bacteroidetes	I	Methylmalonyl-CoA mutase	mutA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DTH2_k127_2617875_1	385682.AFSL01000019_gene2217	3.261e-245	776.0	COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,2G0DC@200643|Bacteroidia,3XJNG@558415|Marinilabiliaceae	976|Bacteroidetes	L	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH2_k127_2617875_6	1168034.FH5T_22120	5.906e-54	191.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,2FT8J@200643|Bacteroidia	976|Bacteroidetes	J	endoribonuclease L-PSP	ridA	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_2617875_3	1168289.AJKI01000008_gene752	4.573e-197	645.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,2FM9F@200643|Bacteroidia,3XIY8@558415|Marinilabiliaceae	976|Bacteroidetes	M	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2644165_0	326427.Cagg_0392	4.862e-56	202.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
DTH2_k127_2649325_0	593750.Metfor_1620	0.0	1059.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,2N91U@224756|Methanomicrobia	224756|Methanomicrobia	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
DTH2_k127_2667773_1	762984.HMPREF9445_03062	7.051e-23	99.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,2FMAW@200643|Bacteroidia,4AK8N@815|Bacteroidaceae	976|Bacteroidetes	P	COG COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH2_k127_2667773_0	243231.GSU2599	1.039e-75	266.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,43TYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
DTH2_k127_2681712_0	744872.Spica_2651	7.501e-95	322.0	COG1208@1|root,COG1208@2|Bacteria,2J5V0@203691|Spirochaetes	203691|Spirochaetes	JM	Domain of unknown function (DUF4954)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4954
DTH2_k127_2681712_1	143224.JQMD01000002_gene2486	1.071e-37	151.0	2CJWE@1|root,30Y1E@2|Bacteria,4NNQQ@976|Bacteroidetes,1I40A@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2681712_2	1107311.Q767_01985	4.852e-34	139.0	COG3209@1|root,COG3209@2|Bacteria,4NRDA@976|Bacteroidetes,1I3N8@117743|Flavobacteriia,2NZ0Z@237|Flavobacterium	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2692326_1	869213.JCM21142_3823	1.68e-204	651.0	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,4NF52@976|Bacteroidetes,47NEH@768503|Cytophagia	976|Bacteroidetes	P	COGs COG0471 Di- and tricarboxylate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
DTH2_k127_2692326_2	926562.Oweho_3302	9.864e-181	594.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia,2PA6D@246874|Cryomorphaceae	976|Bacteroidetes	DM	Chain length determinant protein	wzc	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR,Wzz
DTH2_k127_2692326_4	1121904.ARBP01000018_gene2609	1.084e-42	166.0	COG1596@1|root,COG1596@2|Bacteria,4NFXJ@976|Bacteroidetes,47VGP@768503|Cytophagia	976|Bacteroidetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
DTH2_k127_2692326_3	929556.Solca_4041	4.837e-132	431.0	COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the arginase family	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_2692326_0	929556.Solca_1202	7.873e-285	893.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,4NF9S@976|Bacteroidetes,1IPJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
DTH2_k127_2698152_2	1122173.AXVL01000026_gene1938	2.002e-64	226.0	COG1134@1|root,COG1134@2|Bacteria,37BCJ@32066|Fusobacteria	32066|Fusobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
DTH2_k127_2698152_3	316067.Geob_1442	3.775e-62	223.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42PRV@68525|delta/epsilon subdivisions,2WQT9@28221|Deltaproteobacteria,43T8N@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
DTH2_k127_2698152_1	1173026.Glo7428_0892	4.692e-72	254.0	28IVI@1|root,2Z8TY@2|Bacteria,1G87H@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
DTH2_k127_2698152_0	349741.Amuc_1248	7.06e-82	278.0	COG0451@1|root,COG0451@2|Bacteria,46SD9@74201|Verrucomicrobia,2ITY4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH2_k127_2700298_0	362418.IW19_10325	1.572e-84	287.0	COG0332@1|root,COG0332@2|Bacteria,4NFZK@976|Bacteroidetes,1I1T1@117743|Flavobacteriia,2NUSZ@237|Flavobacterium	976|Bacteroidetes	I	Chalcone and stilbene synthases, N-terminal domain	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_2700298_1	762903.Pedsa_0671	2.528e-57	217.0	COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,1IP1E@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
DTH2_k127_2725961_1	1396.DJ87_5427	6.06e-06	50.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus	91061|Bacilli	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_2725961_0	1121413.JMKT01000015_gene284	5.606e-111	376.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH2_k127_273680_3	1408473.JHXO01000010_gene3545	3.617e-33	132.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,2FS1D@200643|Bacteroidia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH2_k127_273680_1	946077.W5A_06436	1.024e-90	312.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1HXJE@117743|Flavobacteriia	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_273680_0	1168289.AJKI01000002_gene2587	2.957e-95	316.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,2FRNC@200643|Bacteroidia,3XJ1M@558415|Marinilabiliaceae	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_273680_2	1408473.JHXO01000010_gene3548	5.804e-62	222.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,2FTPA@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2740743_4	1121373.KB903666_gene1342	5.571e-16	81.0	COG2834@1|root,COG2834@2|Bacteria,4NT30@976|Bacteroidetes,47RSE@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
DTH2_k127_2740743_3	1434325.AZQN01000002_gene729	1.65e-18	89.0	COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,47SUB@768503|Cytophagia	976|Bacteroidetes	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
DTH2_k127_2740743_5	1121286.AUMT01000003_gene2030	4.588e-10	66.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1I1DC@117743|Flavobacteriia,3ZRSB@59732|Chryseobacterium	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
DTH2_k127_2740743_2	468059.AUHA01000003_gene1564	2.052e-36	143.0	COG2010@1|root,COG2010@2|Bacteria,4NSE3@976|Bacteroidetes,1IT2V@117747|Sphingobacteriia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
DTH2_k127_2740743_0	1123008.KB905694_gene1758	3.054e-124	409.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,2FQIT@200643|Bacteroidia,22X2B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
DTH2_k127_2740743_1	1250278.JQNQ01000001_gene3696	2.105e-56	210.0	COG4258@1|root,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1HYZW@117743|Flavobacteriia	976|Bacteroidetes	I	glycerol acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
DTH2_k127_2742308_2	1237149.C900_00992	9.349e-27	110.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH2_k127_2742308_1	1237149.C900_00992	8.493e-132	430.0	COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH2_k127_2742308_0	886379.AEWI01000122_gene1868	7.127e-313	973.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,2FMC9@200643|Bacteroidia,3XJ6E@558415|Marinilabiliaceae	976|Bacteroidetes	S	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
DTH2_k127_2742308_3	880526.KE386488_gene1391	4.013e-14	84.0	28M15@1|root,2ZAG0@2|Bacteria,4NJBY@976|Bacteroidetes,2FMGZ@200643|Bacteroidia,22URV@171550|Rikenellaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4831)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4831
DTH2_k127_2750774_12	1173020.Cha6605_1944	9.127e-36	142.0	COG0716@1|root,COG0716@2|Bacteria,1G55J@1117|Cyanobacteria	1117|Cyanobacteria	C	Low-potential electron donor to a number of redox enzymes	-	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
DTH2_k127_2750774_1	1408473.JHXO01000011_gene2955	2.748e-151	492.0	COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,2FN2R@200643|Bacteroidia	976|Bacteroidetes	M	Transglycosylase SLT domain protein	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
DTH2_k127_2750774_0	755732.Fluta_2344	9.16e-194	632.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,2PBF0@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DTH2_k127_2750774_5	1469557.JSWF01000035_gene940	1.341e-113	377.0	COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes,1HYPJ@117743|Flavobacteriia	976|Bacteroidetes	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_2750774_3	1168034.FH5T_02845	2.517e-129	422.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,2FMJ3@200643|Bacteroidia	976|Bacteroidetes	V	Transport permease protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_2750774_6	1123037.AUDE01000006_gene1129	3.93e-110	361.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ6V@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_2750774_4	929556.Solca_2545	2.906e-120	392.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1IQRB@117747|Sphingobacteriia	976|Bacteroidetes	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_2750774_8	1408473.JHXO01000006_gene1350	2.205e-81	280.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes,2G0E5@200643|Bacteroidia	976|Bacteroidetes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH2_k127_2750774_7	616991.JPOO01000003_gene2388	1.257e-82	290.0	COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,1HXCD@117743|Flavobacteriia,23GW7@178469|Arenibacter	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_2750774_10	1168034.FH5T_02815	8.38e-51	187.0	COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,2FU2E@200643|Bacteroidia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH2_k127_2750774_11	742817.HMPREF9449_02027	5.709e-50	191.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,2FNVF@200643|Bacteroidia,22XZM@171551|Porphyromonadaceae	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
DTH2_k127_2750774_2	290315.Clim_0965	1.408e-150	496.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1FE17@1090|Chlorobi	1090|Chlorobi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
DTH2_k127_2750774_9	869213.JCM21142_137	1.175e-80	271.0	COG3303@1|root,COG3303@2|Bacteria,4NG0P@976|Bacteroidetes,47JAN@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
DTH2_k127_2758816_1	1121405.dsmv_0797	6.433e-59	211.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MNCE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
DTH2_k127_2758816_0	933262.AXAM01000037_gene886	1.125e-103	349.0	COG2204@1|root,COG2204@2|Bacteria,1QWNE@1224|Proteobacteria,43BTE@68525|delta/epsilon subdivisions,2X746@28221|Deltaproteobacteria,2MPJR@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
DTH2_k127_276669_1	886379.AEWI01000041_gene2808	6.625e-97	323.0	COG1304@1|root,COG1304@2|Bacteria,4NJPE@976|Bacteroidetes,2FWAJ@200643|Bacteroidia,3XIJD@558415|Marinilabiliaceae	976|Bacteroidetes	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
DTH2_k127_276669_5	1121373.KB903620_gene2236	7.54e-05	52.0	2DYZI@1|root,34BWN@2|Bacteria,4P6GP@976|Bacteroidetes,47W61@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4468) with TBP-like fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF4468
DTH2_k127_276669_0	925409.KI911562_gene2316	1.68e-256	799.0	COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,1INP2@117747|Sphingobacteriia	976|Bacteroidetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH2_k127_276669_2	1124780.ANNU01000023_gene3188	2.938e-41	153.0	COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia	976|Bacteroidetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DTH2_k127_276669_3	999419.HMPREF1077_00724	2.184e-22	100.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia,22YIT@171551|Porphyromonadaceae	976|Bacteroidetes	U	Preprotein translocase	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
DTH2_k127_276669_4	1408473.JHXO01000001_gene2394	3.584e-11	70.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,2FQ6G@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_278295_3	997884.HMPREF1068_02837	2.2e-26	114.0	COG3086@1|root,COG3086@2|Bacteria,4NV0R@976|Bacteroidetes,2FS4Y@200643|Bacteroidia,4AQM8@815|Bacteroidaceae	976|Bacteroidetes	T	Positive regulator of sigma(E), RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
DTH2_k127_278295_0	459349.CLOAM0891	5.013e-115	398.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
DTH2_k127_278295_2	929556.Solca_0390	1.141e-72	253.0	COG1028@1|root,COG1028@2|Bacteria,4PKBF@976|Bacteroidetes,1J0YN@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_278295_4	926556.Echvi_1157	5.78e-13	75.0	2E4SF@1|root,32ZKW@2|Bacteria,4NV4G@976|Bacteroidetes,47RXS@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4783
DTH2_k127_278295_1	203275.BFO_1993	4.437e-102	339.0	COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,2FMJM@200643|Bacteroidia,22X4A@171551|Porphyromonadaceae	976|Bacteroidetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
DTH2_k127_2792676_0	1121472.AQWN01000007_gene1136	1.21e-190	607.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia,260G2@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH2_k127_2792676_2	1237149.C900_03809	3.66e-50	184.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,47R7B@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_2792676_1	385682.AFSL01000079_gene1025	1.657e-111	370.0	COG1290@1|root,COG1290@2|Bacteria,4NKHK@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B,Cytochrome_CBB3
DTH2_k127_2809906_1	742726.HMPREF9448_01610	2.685e-119	388.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia,22WBW@171551|Porphyromonadaceae	976|Bacteroidetes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH2_k127_2809906_0	111105.HR09_06315	1.243e-237	740.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22W4Y@171551|Porphyromonadaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS
DTH2_k127_2835927_9	1046627.BZARG_870	8.907e-08	55.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1I2VR@117743|Flavobacteriia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DTH2_k127_2835927_2	1313301.AUGC01000006_gene105	2.918e-79	268.0	COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes	976|Bacteroidetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DTH2_k127_2835927_6	1286632.P278_01730	2.022e-42	156.0	COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,1I2TX@117743|Flavobacteriia	976|Bacteroidetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DTH2_k127_2835927_4	1150600.ADIARSV_3615	2.357e-64	222.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1IS0B@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DTH2_k127_2835927_3	762903.Pedsa_2133	8.045e-75	255.0	COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia	976|Bacteroidetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DTH2_k127_2835927_7	742817.HMPREF9449_02679	4.072e-42	158.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,22Y3P@171551|Porphyromonadaceae	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
DTH2_k127_2835927_1	468059.AUHA01000002_gene1325	2.04e-83	279.0	COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,1IQ9B@117747|Sphingobacteriia	976|Bacteroidetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DTH2_k127_2835927_8	1550091.JROE01000004_gene1342	6.343e-15	76.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,1IUA3@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
DTH2_k127_2835927_5	1122621.ATZA01000014_gene3228	4.293e-57	202.0	COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,1IRSX@117747|Sphingobacteriia	976|Bacteroidetes	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DTH2_k127_2835927_0	385682.AFSL01000026_gene663	9.546e-170	539.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia,3XISD@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecY translocase	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DTH2_k127_2855086_0	1122226.AUHX01000008_gene1453	3.604e-155	527.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,1HWZS@117743|Flavobacteriia	976|Bacteroidetes	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
DTH2_k127_2855086_1	385682.AFSL01000073_gene1381	2.487e-109	359.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia,3XIM1@558415|Marinilabiliaceae	976|Bacteroidetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH2_k127_2904100_6	385682.AFSL01000041_gene285	9.854e-45	167.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,3XJVP@558415|Marinilabiliaceae	976|Bacteroidetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH2_k127_2904100_7	226186.BT_2414	1.544e-26	109.0	COG2768@1|root,COG2768@2|Bacteria,4NUN8@976|Bacteroidetes,2FUIC@200643|Bacteroidia,4AS5K@815|Bacteroidaceae	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
DTH2_k127_2904100_0	869213.JCM21142_93948	0.0	1148.0	COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia	976|Bacteroidetes	C	2-oxoglutarate dehydrogenase, E1	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
DTH2_k127_2904100_2	755732.Fluta_1300	9.99e-144	467.0	COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1HWNW@117743|Flavobacteriia,2PAA5@246874|Cryomorphaceae	976|Bacteroidetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_2904100_1	385682.AFSL01000096_gene579	3.833e-225	708.0	COG0029@1|root,COG0029@2|Bacteria,4NGUE@976|Bacteroidetes,2FNMT@200643|Bacteroidia,3XIJE@558415|Marinilabiliaceae	976|Bacteroidetes	H	Fumarate reductase flavoprotein C-term	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH2_k127_2904100_4	616991.JPOO01000001_gene3305	6.334e-71	246.0	COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,1HYG2@117743|Flavobacteriia,23GXE@178469|Arenibacter	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH2_k127_2904100_3	1089547.KB913013_gene816	8.524e-72	263.0	COG2885@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,4NGEP@976|Bacteroidetes,47NK0@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_2904100_5	1392489.JPOL01000002_gene3159	3.59e-47	172.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2XK92@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
DTH2_k127_292640_0	1408473.JHXO01000004_gene166	1.132e-132	460.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location OuterMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	TamB
DTH2_k127_292640_1	1121957.ATVL01000006_gene3301	3.078e-44	175.0	2DX8D@1|root,343UE@2|Bacteria,4P6Q1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2947307_0	1168034.FH5T_16615	1.051e-213	681.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,2FNTX@200643|Bacteroidia	976|Bacteroidetes	P	TrkA C-terminal domain protein	kefC	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
DTH2_k127_2948299_1	1346330.M472_07010	2.613e-76	259.0	COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DTH2_k127_2948299_0	1237149.C900_01037	2.036e-79	269.0	COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,47J8V@768503|Cytophagia	976|Bacteroidetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DTH2_k127_2948299_2	869213.JCM21142_31248	7.499e-34	132.0	COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,47R4F@768503|Cytophagia	976|Bacteroidetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DTH2_k127_2948299_3	1313301.AUGC01000006_gene113	7.142e-31	122.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes	976|Bacteroidetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DTH2_k127_2956434_1	880526.KE386488_gene513	5.198e-15	74.0	COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,2FT32@200643|Bacteroidia,22UHK@171550|Rikenellaceae	976|Bacteroidetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DTH2_k127_2956434_0	385682.AFSL01000026_gene641	1.714e-187	596.0	COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,3XJ5X@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_2959795_4	1168289.AJKI01000012_gene306	4.027e-26	111.0	COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,2FPAJ@200643|Bacteroidia,3XJ34@558415|Marinilabiliaceae	976|Bacteroidetes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_2959795_2	1484460.JSWG01000001_gene2403	1.285e-63	225.0	COG0457@1|root,COG0457@2|Bacteria,4NSW4@976|Bacteroidetes,1I4RX@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2959795_3	373994.Riv7116_1332	5.068e-54	200.0	COG0463@1|root,COG0463@2|Bacteria,1GQ4G@1117|Cyanobacteria,1HN6Q@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
DTH2_k127_2959795_6	1121895.Q765_17575	3.477e-05	54.0	COG0526@1|root,COG0526@2|Bacteria,4P2YC@976|Bacteroidetes,1I8S9@117743|Flavobacteriia,2NTRQ@237|Flavobacterium	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
DTH2_k127_2959795_1	760192.Halhy_4528	4.432e-116	380.0	COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,1IQ2W@117747|Sphingobacteriia	976|Bacteroidetes	M	2-dehydro-3-deoxyphosphooctonate aldolase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
DTH2_k127_2959795_0	1237149.C900_03862	1.9e-175	559.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,47JM9@768503|Cytophagia	976|Bacteroidetes	L	PFAM MgsA AAA ATPase C terminal	ycaJ	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DTH2_k127_2959795_5	313606.M23134_04188	4.319e-06	50.0	COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,47KX5@768503|Cytophagia	976|Bacteroidetes	H	Nicotinate-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_2962868_1	1191523.MROS_0147	4.409e-189	595.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
DTH2_k127_2962868_3	1191523.MROS_0148	3.527e-126	415.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
DTH2_k127_2962868_0	234267.Acid_2314	3.859e-235	746.0	COG3387@1|root,COG3387@2|Bacteria,3Y3QW@57723|Acidobacteria	57723|Acidobacteria	G	Domain of unknown function (DUF5127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127
DTH2_k127_2962868_2	350688.Clos_0825	2.168e-143	463.0	COG0031@1|root,COG0031@2|Bacteria,1UZEQ@1239|Firmicutes,24BCR@186801|Clostridia,36G6F@31979|Clostridiaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH2_k127_2989853_1	1123248.KB893386_gene1898	1.081e-108	354.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
DTH2_k127_2989853_3	1122176.KB903609_gene5127	9.333e-14	74.0	COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1IUIX@117747|Sphingobacteriia	976|Bacteroidetes	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
DTH2_k127_2989853_0	1121904.ARBP01000016_gene5290	3.042e-268	847.0	COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_2989853_2	385682.AFSL01000105_gene104	6.149e-83	279.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,4NDY1@976|Bacteroidetes,2FKZ1@200643|Bacteroidia,3XITP@558415|Marinilabiliaceae	976|Bacteroidetes	O	Cytochrome C assembly protein	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
DTH2_k127_3021787_1	1347342.BN863_15680	9.657e-153	497.0	COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia	976|Bacteroidetes	P	COG0471 Di- and tricarboxylate	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
DTH2_k127_3021787_2	439235.Dalk_3949	5.638e-78	271.0	COG0697@1|root,COG0697@2|Bacteria,1QBAD@1224|Proteobacteria,42PAK@68525|delta/epsilon subdivisions,2WKBB@28221|Deltaproteobacteria,2MJW1@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_3021787_0	1168034.FH5T_19585	6.63e-170	545.0	COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,2G336@200643|Bacteroidia	976|Bacteroidetes	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
DTH2_k127_3021787_3	1166018.FAES_0007	5.116e-08	59.0	COG3746@1|root,COG3746@2|Bacteria,4NIRE@976|Bacteroidetes,47N4T@768503|Cytophagia	976|Bacteroidetes	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH2_k127_3036167_0	742725.HMPREF9450_01835	9.618e-309	953.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,2FM9V@200643|Bacteroidia,22UZW@171550|Rikenellaceae	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH2_k127_3036167_1	1406840.Q763_15170	1.203e-114	374.0	COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,1HYY2@117743|Flavobacteriia,2NSN5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
DTH2_k127_3036167_5	1121875.KB907546_gene2466	2.231e-35	144.0	COG1670@1|root,COG1670@2|Bacteria,4NNE4@976|Bacteroidetes,1I1AJ@117743|Flavobacteriia	976|Bacteroidetes	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_3036167_2	1121451.DESAM_22201	1.369e-93	319.0	COG0438@1|root,COG0438@2|Bacteria,1NF2Z@1224|Proteobacteria,42V61@68525|delta/epsilon subdivisions,2WS5P@28221|Deltaproteobacteria,2M8T0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
DTH2_k127_3036167_3	760192.Halhy_2467	2.218e-88	299.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1ISZE@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
DTH2_k127_3036167_4	1168289.AJKI01000002_gene2553	7.344e-56	199.0	COG1595@1|root,COG1595@2|Bacteria,4NQ7S@976|Bacteroidetes,2FTDI@200643|Bacteroidia,3XK6J@558415|Marinilabiliaceae	976|Bacteroidetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_3036167_7	1168034.FH5T_07975	3.63e-13	81.0	2DP4F@1|root,330H1@2|Bacteria,4NX9Z@976|Bacteroidetes,2FVZZ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3036167_6	1121957.ATVL01000010_gene354	3.893e-16	84.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RTK@768503|Cytophagia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
DTH2_k127_3058438_0	1239962.C943_04333	4.405e-218	696.0	COG0037@1|root,COG0449@1|root,COG0037@2|Bacteria,COG0449@2|Bacteria,4NIZR@976|Bacteroidetes	976|Bacteroidetes	D	LPS biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3059528_1	1163617.SCD_n00004	6.683e-74	249.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DTH2_k127_3059528_0	1123393.KB891317_gene2351	1.293e-124	410.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,1KRKI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Uncharacterized protein conserved in bacteria (DUF2331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
DTH2_k127_3099430_2	517418.Ctha_1895	1.535e-59	210.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	purD	-	6.3.4.13,6.3.5.5	ko:K01945,ko:K01955	ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130	M00048,M00051	R00256,R00575,R01395,R04144,R10948,R10949	RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,ATP-grasp_3,ATP-grasp_4,CPSase_L_D2,GARS_A
DTH2_k127_3099430_7	1123057.P872_15945	2.075e-13	74.0	2EBCA@1|root,335D0@2|Bacteria,4NUYY@976|Bacteroidetes,47VEH@768503|Cytophagia	976|Bacteroidetes	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
DTH2_k127_3099430_4	945713.IALB_3074	3.958e-37	146.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin,Thioredoxin_2,Thioredoxin_9
DTH2_k127_3099430_0	1123277.KB893185_gene3060	1.933e-87	297.0	COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
DTH2_k127_3099430_5	1305737.JAFX01000001_gene2966	9.566e-36	139.0	COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,47QA8@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
DTH2_k127_3099430_1	929556.Solca_3493	1.077e-59	220.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_3099430_3	1121129.KB903360_gene3405	5.368e-58	206.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,2FU16@200643|Bacteroidia	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
DTH2_k127_3099430_6	926562.Oweho_1541	1.357e-18	87.0	2A8XB@1|root,30Y0U@2|Bacteria,4NSDA@976|Bacteroidetes,1I4EZ@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_3127358_1	1047013.AQSP01000092_gene315	2.826e-153	501.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH2_k127_3127358_0	1168034.FH5T_15260	7.485e-231	738.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
DTH2_k127_3130991_0	1122176.KB903535_gene2050	6.247e-158	505.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1IPKV@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_3130991_1	95619.PM1_0211645	5.137e-28	123.0	COG2867@1|root,COG2867@2|Bacteria,1N681@1224|Proteobacteria,1SAUK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	START domain	-	-	-	-	-	-	-	-	-	-	-	-	START
DTH2_k127_3130991_2	1267534.KB906754_gene3483	5.786e-09	59.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,VCBS
DTH2_k127_3132424_1	1408433.JHXV01000005_gene2290	1.839e-12	81.0	COG1729@1|root,COG1729@2|Bacteria,4PMDU@976|Bacteroidetes,1IKE6@117743|Flavobacteriia,2PB2R@246874|Cryomorphaceae	976|Bacteroidetes	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
DTH2_k127_3132424_0	1449126.JQKL01000006_gene782	2.096e-29	128.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,26A5Y@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_3132424_2	1381123.AYOD01000048_gene285	0.0004075	52.0	COG2304@1|root,COG2304@2|Bacteria,1MXU0@1224|Proteobacteria,2TU9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	VWA,VWA_2
DTH2_k127_3135156_2	1501391.LG35_07055	6.335e-161	520.0	COG2271@1|root,COG2271@2|Bacteria,4PKTC@976|Bacteroidetes,2G3HT@200643|Bacteroidia,22V02@171550|Rikenellaceae	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_3135156_1	1408473.JHXO01000011_gene3050	1.315e-184	589.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia	976|Bacteroidetes	E	Xaa-His dipeptidase	pepD_2	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_3135156_5	1313421.JHBV01000026_gene419	3.844e-18	84.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DTH2_k127_3135156_0	1408473.JHXO01000010_gene3748	2.858e-236	756.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH2_k127_3135156_3	694427.Palpr_1324	6.2e-125	417.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,2FS76@200643|Bacteroidia,22XPD@171551|Porphyromonadaceae	976|Bacteroidetes	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DTH2_k127_3135156_4	1122176.KB903609_gene5195	2.711e-89	301.0	COG2227@1|root,COG2227@2|Bacteria,4NJ5I@976|Bacteroidetes,1IW68@117747|Sphingobacteriia	976|Bacteroidetes	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
DTH2_k127_3136642_4	555500.I215_10325	1.145e-45	175.0	COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,1HXT1@117743|Flavobacteriia	976|Bacteroidetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
DTH2_k127_3136642_0	313606.M23134_05475	0.0	1791.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
DTH2_k127_3136642_5	1185876.BN8_01332	3.896e-25	110.0	28V5G@1|root,2ZH8R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH2_k127_3136642_1	1185876.BN8_01333	2.001e-161	512.0	2EGJ6@1|root,33ABD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3136642_3	1031288.AXAA01000001_gene2267	2.376e-65	229.0	COG1243@1|root,COG1243@2|Bacteria,1TS1F@1239|Firmicutes,248YV@186801|Clostridia,36DYS@31979|Clostridiaceae	186801|Clostridia	BK	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,Radical_SAM_C
DTH2_k127_3145810_2	388413.ALPR1_01925	2.078e-25	108.0	COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,47R6S@768503|Cytophagia	976|Bacteroidetes	H	TIGRFAM Nicotinamide mononucleotide transporter PnuC	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
DTH2_k127_3145810_1	1124780.ANNU01000005_gene2441	7.167e-55	197.0	COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,47QMU@768503|Cytophagia	976|Bacteroidetes	H	ATPase kinase involved in NAD metabolism	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28
DTH2_k127_3145810_0	694427.Palpr_0806	1.389e-86	300.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,2FP8H@200643|Bacteroidia,22YMG@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_3164555_10	929556.Solca_2230	1.156e-12	71.0	COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
DTH2_k127_3164555_9	1168034.FH5T_16975	2.12e-41	166.0	2DRZU@1|root,33DVD@2|Bacteria,4P3PD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3164555_8	1168034.FH5T_16980	6.926e-43	166.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	Z012_05310	-	-	ko:K01420,ko:K10914,ko:K21556,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_3164555_5	929556.Solca_2317	6.681e-171	547.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1IPIA@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1,MFS_2
DTH2_k127_3164555_6	1150600.ADIARSV_3917	4.484e-80	287.0	COG1807@1|root,COG1807@2|Bacteria,4NIT6@976|Bacteroidetes,1IRPE@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_3164555_7	880073.Calab_2976	1.002e-75	259.0	COG0572@1|root,COG0572@2|Bacteria,2NRHW@2323|unclassified Bacteria	2|Bacteria	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_18,AAA_33,Hydrolase_like,NTP_transferase,PRK,RNA_lig_T4_1
DTH2_k127_3164555_0	880073.Calab_2975	0.0	1170.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,2NQF1@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 65, C-terminal domain	pgmB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576	2.4.1.216,2.4.1.64,2.4.1.8,3.1.3.12,3.2.1.28,5.4.2.6	ko:K00691,ko:K01087,ko:K01194,ko:K01838,ko:K03731,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R01555,R02727,R02728,R02778,R11310	RC00017,RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
DTH2_k127_3164555_2	1499967.BAYZ01000006_gene5473	7.419e-189	606.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K01176,ko:K05343	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	APH,Alpha-amylase,Malt_amylase_C
DTH2_k127_3164555_1	927658.AJUM01000024_gene2521	3.656e-193	621.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,2FMHS@200643|Bacteroidia,3XINW@558415|Marinilabiliaceae	976|Bacteroidetes	G	Alpha-amylase domain	amyA2	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016798,GO:0031216,GO:0044464,GO:0071944	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
DTH2_k127_3164555_4	234267.Acid_4507	1.208e-176	568.0	COG0366@1|root,COG0366@2|Bacteria,3Y2P1@57723|Acidobacteria	57723|Acidobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
DTH2_k127_3164555_3	742817.HMPREF9449_02820	1.826e-178	576.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,2FMHS@200643|Bacteroidia,22W2Q@171551|Porphyromonadaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
DTH2_k127_3179749_0	1279009.ADICEAN_01863	2.235e-147	479.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,47KSA@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
DTH2_k127_3179749_1	1279009.ADICEAN_01862	4.441e-110	367.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KYY@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_3183390_2	224719.Abm4_1311	9.851e-54	202.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,23PFJ@183925|Methanobacteria	183925|Methanobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH2_k127_3183390_1	673860.AciM339_0523	3.037e-63	224.0	COG0463@1|root,arCOG00894@2157|Archaea,2XUJ6@28890|Euryarchaeota,3F38U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_3183390_0	1313421.JHBV01000044_gene2919	4.047e-74	261.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,1ITJC@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
DTH2_k127_3187807_0	1121920.AUAU01000009_gene1859	4.75e-140	449.0	COG0437@1|root,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	-
DTH2_k127_3187807_2	1121920.AUAU01000009_gene1858	1.501e-56	203.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH2_k127_3187807_3	1235835.C814_02259	5.078e-12	72.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24J98@186801|Clostridia,3WJY6@541000|Ruminococcaceae	186801|Clostridia	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
DTH2_k127_3187807_1	926550.CLDAP_04870	1.999e-114	393.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH2_k127_3215910_1	448385.sce1143	1.097e-21	110.0	COG3210@1|root,COG3210@2|Bacteria,1QW1H@1224|Proteobacteria	1224|Proteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3215910_0	1191523.MROS_0118	1.711e-256	841.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	HATPase_c,HTH_18,HisKA,PAS_4,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_3215910_2	1121930.AQXG01000005_gene601	2.436e-12	75.0	COG1404@1|root,COG1404@2|Bacteria,4NVH2@976|Bacteroidetes,1IURU@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3228363_0	1433126.BN938_3060	1.097e-202	641.0	COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,22U9Y@171550|Rikenellaceae	976|Bacteroidetes	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_3237018_1	1120951.AUBG01000011_gene2340	7.546e-92	318.0	COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1HY00@117743|Flavobacteriia	976|Bacteroidetes	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DTH2_k127_3237018_2	1408433.JHXV01000008_gene146	1.093e-40	151.0	COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1I2WI@117743|Flavobacteriia,2PAZN@246874|Cryomorphaceae	976|Bacteroidetes	L	bacterial (prokaryotic) histone like domain	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_3237018_3	714943.Mucpa_2551	1.36e-06	50.0	2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3237018_0	1286632.P278_25750	1.062e-162	521.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1HWJC@117743|Flavobacteriia	976|Bacteroidetes	J	ribonuclease G	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
DTH2_k127_3240105_1	991.IW20_23510	7.543e-46	176.0	COG3520@1|root,COG3520@2|Bacteria,4NM5X@976|Bacteroidetes,1I1EG@117743|Flavobacteriia,2NT4X@237|Flavobacterium	976|Bacteroidetes	S	type VI secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_TssG
DTH2_k127_3240105_0	760192.Halhy_4602	4.541e-52	212.0	COG3210@1|root,COG3591@1|root,COG3210@2|Bacteria,COG3591@2|Bacteria,4NTMJ@976|Bacteroidetes	976|Bacteroidetes	U	Putative binding domain, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BACON
DTH2_k127_3240105_2	313598.MED152_08630	4.35e-07	64.0	COG3210@1|root,COG3420@1|root,COG3210@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.19,4.2.2.3	ko:K01729,ko:K09942,ko:K19053	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	PL6	-	CHU_C,Chondroitinas_B,PT-VENN
DTH2_k127_3272354_1	1121889.AUDM01000028_gene491	6.715e-171	577.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,Cleaved_Adhesin,MAM,fn3
DTH2_k127_3272354_2	755732.Fluta_3336	5.456e-24	120.0	COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1HY1V@117743|Flavobacteriia,2PBEH@246874|Cryomorphaceae	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_3272354_0	96561.Dole_2113	3.142e-213	670.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MIUW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH2_k127_3272354_3	118168.MC7420_6994	3.291e-18	94.0	COG0500@1|root,COG2226@2|Bacteria,1GQVD@1117|Cyanobacteria	1117|Cyanobacteria	Q	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
DTH2_k127_3272354_4	1313301.AUGC01000009_gene1060	2.004e-06	59.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	tuaF	-	-	ko:K07011,ko:K16706	-	-	-	-	ko00000	-	-	-	GNVR,Wzz
DTH2_k127_3280862_1	616991.JPOO01000003_gene2491	1.353e-70	248.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,1HXZ5@117743|Flavobacteriia,23GP3@178469|Arenibacter	976|Bacteroidetes	M	Bacterial SH3 domain	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
DTH2_k127_3280862_0	468059.AUHA01000006_gene2985	1.658e-192	610.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,1IRQU@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH2_k127_3280923_2	1519464.HY22_00065	2.421e-127	414.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH2_k127_3280923_5	880074.BARVI_08990	2.426e-75	262.0	COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,2FN1A@200643|Bacteroidia,22WFR@171551|Porphyromonadaceae	976|Bacteroidetes	H	Methyltransferase	rsmI_1	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH2_k127_3280923_6	1121373.KB903626_gene3331	7.64e-48	176.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DTH2_k127_3280923_4	1237149.C900_02648	7.822e-98	327.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,47Q1V@768503|Cytophagia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_3280923_7	1237149.C900_02649	2.084e-34	143.0	COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,47WZW@768503|Cytophagia	976|Bacteroidetes	S	Excinuclease ABC subunit B	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
DTH2_k127_3280923_1	1168034.FH5T_00220	9.04e-154	496.0	COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,2FPDQ@200643|Bacteroidia	976|Bacteroidetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K03799,ko:K06013	ko00900,ko01130,map00900,map01130	M00743	R09845	RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
DTH2_k127_3280923_0	760192.Halhy_1230	8.921e-159	524.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3280923_3	1168289.AJKI01000015_gene2154	1.195e-107	353.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,3XJ35@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	KR domain	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_3289815_3	700598.Niako_6461	1.397e-33	130.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3289815_0	1453500.AT05_06640	3.499e-130	421.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
DTH2_k127_3289815_2	484018.BACPLE_01391	3.878e-54	194.0	COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,2FT2Q@200643|Bacteroidia,4AQK2@815|Bacteroidaceae	976|Bacteroidetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DTH2_k127_3289815_1	313598.MED152_04100	9.113e-73	249.0	COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia,3VW9M@52959|Polaribacter	976|Bacteroidetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DTH2_k127_3289815_4	1122176.KB903554_gene3803	7.227e-15	81.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	LysM,TPR_16,TPR_6,YfiO
DTH2_k127_3311451_4	1236494.BAJN01000006_gene1014	0.0002298	44.0	COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes	976|Bacteroidetes	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,dNK
DTH2_k127_3311451_1	1550091.JROE01000013_gene63	8.458e-128	416.0	COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IQAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_3311451_2	755732.Fluta_2092	2.518e-86	319.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
DTH2_k127_3311451_0	1168034.FH5T_05245	4.496e-222	696.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,2FN9J@200643|Bacteroidia	976|Bacteroidetes	E	Peptidase dimerization domain protein	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_3311451_3	56110.Oscil6304_2815	3.549e-45	176.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
DTH2_k127_3346047_1	391596.PBAL39_09731	6.124e-81	279.0	COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,1IP0V@117747|Sphingobacteriia	976|Bacteroidetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
DTH2_k127_3346047_0	865938.Weevi_1967	8.78e-84	286.0	COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,1HYDH@117743|Flavobacteriia	976|Bacteroidetes	F	phosphorylase	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_3346047_2	762903.Pedsa_1418	1.439e-36	141.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,1INYU@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DTH2_k127_335315_2	1168034.FH5T_11615	3.457e-62	221.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FRJY@200643|Bacteroidia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_335315_1	1048983.EL17_06270	6.906e-115	386.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia	976|Bacteroidetes	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD,HlyD_3,HlyD_D23
DTH2_k127_335315_0	1408433.JHXV01000009_gene1317	8.101e-123	408.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1HXA1@117743|Flavobacteriia,2PA5W@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_3370451_3	999419.HMPREF1077_00257	3.82e-13	72.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia,22X66@171551|Porphyromonadaceae	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
DTH2_k127_3370451_4	1408433.JHXV01000001_gene975	7.811e-08	63.0	2AC11@1|root,311IW@2|Bacteria,4PGCJ@976|Bacteroidetes,1IMTD@117743|Flavobacteriia,2PC4A@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3370451_0	1191523.MROS_1240	1.479e-188	598.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
DTH2_k127_3370451_1	1484460.JSWG01000011_gene1705	1.331e-97	353.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_3370451_2	1122176.KB903555_gene3765	3.282e-15	91.0	COG1520@1|root,COG3209@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B,SprB,UnbV_ASPIC,VCBS
DTH2_k127_3370821_6	1492737.FEM08_16300	5.268e-12	69.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes,1I809@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3370821_3	926562.Oweho_1087	6.692e-36	143.0	2DKFZ@1|root,309D6@2|Bacteria,4PK7J@976|Bacteroidetes,1IFCY@117743|Flavobacteriia,2PB0S@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
DTH2_k127_3370821_1	391623.TERMP_00782	3.504e-46	175.0	COG4902@1|root,arCOG03957@2157|Archaea,2Y2WW@28890|Euryarchaeota,243M5@183968|Thermococci	183968|Thermococci	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
DTH2_k127_3370821_4	880073.Calab_1806	1.975e-32	135.0	295PX@1|root,2ZT19@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3370821_2	194439.CT0502	1.261e-40	156.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_3370821_5	1270196.JCKI01000003_gene1967	1.521e-23	108.0	COG3208@1|root,COG3208@2|Bacteria,4PM28@976|Bacteroidetes,1J0JP@117747|Sphingobacteriia	976|Bacteroidetes	Q	Thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DTH2_k127_3370821_7	1408813.AYMG01000008_gene3868	0.0001164	46.0	COG3208@1|root,COG3208@2|Bacteria	2|Bacteria	Q	Thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Thioesterase
DTH2_k127_3370821_0	929556.Solca_2304	1.074e-51	187.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1IRWG@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
DTH2_k127_3395194_1	1121373.KB903632_gene480	1.921e-31	127.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
DTH2_k127_3395194_0	1168034.FH5T_20440	4.285e-70	245.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,2FY9U@200643|Bacteroidia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_3395194_2	483219.LILAB_34325	4.801e-22	109.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14,4.2.2.2	ko:K01183,ko:K01728	ko00040,ko00520,ko01100,ko02024,map00040,map00520,map01100,map02024	-	R01206,R02334,R02361,R06240	RC00049,RC00467,RC00705	ko00000,ko00001,ko01000	-	GH18	-	An_peroxidase,Big_5,ChiC,F5_F8_type_C,Flg_new,Glyco_hydro_18,Glyco_hydro_92,Pec_lyase_C,SLH,fn3
DTH2_k127_3418038_4	1004785.AMBLS11_13110	1.143e-17	85.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,1RN4M@1236|Gammaproteobacteria,465P7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	gt2M	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_3418038_2	1168034.FH5T_01205	6.144e-117	389.0	COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,2FQT6@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DTH2_k127_3418038_3	1121904.ARBP01000015_gene162	1.161e-36	144.0	COG0662@1|root,COG0662@2|Bacteria,4NQUX@976|Bacteroidetes	976|Bacteroidetes	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3418038_1	1158294.JOMI01000009_gene986	1.726e-186	592.0	COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,2FM6I@200643|Bacteroidia	976|Bacteroidetes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DTH2_k127_3418038_5	749222.Nitsa_1039	1.214e-14	79.0	COG0526@1|root,COG0526@2|Bacteria,1N9U2@1224|Proteobacteria,43BDE@68525|delta/epsilon subdivisions,2YT7U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
DTH2_k127_3418038_0	1047013.AQSP01000140_gene2469	1.503e-271	841.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH2_k127_3451984_7	1121448.DGI_1745	8.716e-15	76.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,42X36@68525|delta/epsilon subdivisions,2WSNU@28221|Deltaproteobacteria,2MDMZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3451984_5	1121440.AUMA01000015_gene1864	6.918e-23	102.0	2CH0Y@1|root,3309M@2|Bacteria,1NF9M@1224|Proteobacteria,42VBP@68525|delta/epsilon subdivisions,2WRWS@28221|Deltaproteobacteria,2MB1U@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3451984_3	1178482.BJB45_13405	7.21e-91	320.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1XH8V@135619|Oceanospirillales	135619|Oceanospirillales	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH2_k127_3451984_1	1107311.Q767_03015	1.371e-167	535.0	COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,1I5BI@117743|Flavobacteriia,2NVIG@237|Flavobacterium	976|Bacteroidetes	S	COG NOG10142 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3451984_4	388413.ALPR1_16618	2.524e-55	199.0	COG3153@1|root,COG3153@2|Bacteria,4NP1G@976|Bacteroidetes,47QSB@768503|Cytophagia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,Zn_ribbon_2
DTH2_k127_3451984_2	331678.Cphamn1_1084	5.2e-143	461.0	COG1064@1|root,COG1064@2|Bacteria,1FERU@1090|Chlorobi	1090|Chlorobi	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
DTH2_k127_3451984_9	459349.CLOAM0061	1.25e-08	68.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
DTH2_k127_3451984_8	941449.dsx2_0417	1.976e-10	74.0	COG0642@1|root,COG3292@1|root,COG4191@1|root,COG5002@1|root,COG0642@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,43DCX@68525|delta/epsilon subdivisions,2X8IU@28221|Deltaproteobacteria,2MHI9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_3451984_0	1121875.KB907549_gene2024	1.682e-213	673.0	COG2303@1|root,COG2303@2|Bacteria,4NMEP@976|Bacteroidetes,1IA7R@117743|Flavobacteriia	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C
DTH2_k127_3459473_1	385682.AFSL01000089_gene937	5.187e-187	590.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,3XJJ7@558415|Marinilabiliaceae	976|Bacteroidetes	J	DALR_2	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DTH2_k127_3459473_2	945713.IALB_2820	4.266e-58	204.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_3459473_0	118005.AWNK01000005_gene1604	2.36e-249	785.0	COG0480@1|root,COG0480@2|Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_3464281_1	1158294.JOMI01000002_gene2812	1.987e-244	762.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DTH2_k127_3464281_3	927658.AJUM01000010_gene1343	2.342e-81	280.0	COG4783@1|root,COG4783@2|Bacteria,4PKN7@976|Bacteroidetes,2G1NH@200643|Bacteroidia,3XKPB@558415|Marinilabiliaceae	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH2_k127_3464281_4	1501391.LG35_01720	9.231e-63	222.0	COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22VAD@171550|Rikenellaceae	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DTH2_k127_3464281_6	929713.NIASO_10750	7.935e-23	99.0	COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1ITVV@117747|Sphingobacteriia	976|Bacteroidetes	C	ATP synthase	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
DTH2_k127_3464281_0	929556.Solca_2789	4.586e-261	812.0	COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia	976|Bacteroidetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH2_k127_3464281_2	1408473.JHXO01000006_gene1115	2.045e-136	439.0	COG0506@1|root,COG0506@2|Bacteria,4NKZB@976|Bacteroidetes,2FW9Q@200643|Bacteroidia	976|Bacteroidetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DTH2_k127_3464281_5	1408473.JHXO01000010_gene3773	6.654e-39	151.0	COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,2FPCJ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
DTH2_k127_3464281_7	485917.Phep_3815	6.234e-20	90.0	COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,1IU0H@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DTH2_k127_3464281_8	1433126.BN938_1350	1.68e-09	59.0	COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,2G1NW@200643|Bacteroidia,22TZ9@171550|Rikenellaceae	976|Bacteroidetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DTH2_k127_3487896_1	679926.Mpet_0316	1.146e-37	149.0	COG2426@1|root,arCOG01330@2157|Archaea,2Y4KG@28890|Euryarchaeota	28890|Euryarchaeota	S	Small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DTH2_k127_3487896_0	456442.Mboo_0578	8.821e-42	157.0	COG3324@1|root,arCOG04946@2157|Archaea	2157|Archaea	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
DTH2_k127_3487896_2	456442.Mboo_0318	5.151e-15	75.0	COG4022@1|root,arCOG04893@2157|Archaea,2XVN1@28890|Euryarchaeota,2N9I3@224756|Methanomicrobia	224756|Methanomicrobia	S	Methanogenesis marker protein 8	-	-	-	-	-	-	-	-	-	-	-	-	DUF2099
DTH2_k127_3511066_1	1121468.AUBR01000023_gene2758	1.731e-89	302.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,42ERP@68295|Thermoanaerobacterales	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
DTH2_k127_3511066_2	555088.DealDRAFT_0059	0.0002535	46.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS,Ub-Mut7C
DTH2_k127_3511066_0	926569.ANT_02040	3.593e-116	378.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
DTH2_k127_3563372_1	880073.Calab_3356	7.076e-97	336.0	COG0737@1|root,COG1506@1|root,COG2356@1|root,COG4935@1|root,COG0737@2|Bacteria,COG1506@2|Bacteria,COG2356@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.17.18	ko:K05996,ko:K06889,ko:K07214	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CotH,Peptidase_S9,SBP_bac_8,SLH
DTH2_k127_3563372_2	945713.IALB_1824	1.816e-60	238.0	COG1470@1|root,COG3391@1|root,COG4412@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	mxcI	-	3.4.21.50	ko:K01337,ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	ASH,CarboxypepD_reg
DTH2_k127_3563372_3	1237149.C900_05552	7.722e-24	119.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,47TYM@768503|Cytophagia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
DTH2_k127_3563372_4	313606.M23134_03411	5.869e-13	78.0	2EN4P@1|root,33FSQ@2|Bacteria,4NZ3C@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3563372_0	1168289.AJKI01000016_gene1946	4.68e-288	910.0	COG2730@1|root,COG2730@2|Bacteria,4NH83@976|Bacteroidetes,2FNQD@200643|Bacteroidia,3XJ3H@558415|Marinilabiliaceae	976|Bacteroidetes	G	Carbohydrate binding module (family 6)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
DTH2_k127_3563372_5	880073.Calab_2546	3.776e-12	72.0	COG2372@1|root,COG4733@1|root,COG2372@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	Big_5,DUF4082,SASA,fn3
DTH2_k127_358266_2	929556.Solca_2716	4.142e-95	322.0	COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,1INVB@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Aminoglycoside phosphotransferase	mdsC	-	-	-	-	-	-	-	-	-	-	-	APH
DTH2_k127_358266_3	880073.Calab_2494	7.111e-95	319.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
DTH2_k127_358266_1	926549.KI421517_gene2439	1.253e-153	497.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,47K89@768503|Cytophagia	976|Bacteroidetes	G	TIGRFAM glucose galactose transporter	gluP	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
DTH2_k127_358266_0	1191523.MROS_1490	4.973e-251	789.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
DTH2_k127_3592697_0	700598.Niako_0486	1.675e-64	235.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_3592697_1	1121899.Q764_12445	5.777e-29	118.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1I3FD@117743|Flavobacteriia,2P0EI@237|Flavobacterium	976|Bacteroidetes	T	LytTR family two component system response regulatory protein	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_3597579_0	768704.Desmer_2113	1.127e-80	281.0	COG0611@1|root,COG0611@2|Bacteria,1V0SM@1239|Firmicutes,24J04@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_3597579_1	768706.Desor_2068	4.658e-79	272.0	COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,24QZG@186801|Clostridia,265X2@186807|Peptococcaceae	186801|Clostridia	GM	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.219,1.1.1.412	ko:K00091,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DTH2_k127_3609962_1	1121904.ARBP01000001_gene5529	7.102e-87	299.0	COG3203@1|root,COG3203@2|Bacteria,4PKUC@976|Bacteroidetes,47YNV@768503|Cytophagia	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_3609962_0	1408473.JHXO01000013_gene536	3.99e-251	782.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,2FMZT@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DTH2_k127_3609962_3	926549.KI421517_gene831	4.88e-71	259.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,47K28@768503|Cytophagia	976|Bacteroidetes	I	PFAM Outer membrane protein transport protein (OMPP1 FadL TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
DTH2_k127_3609962_2	342949.PNA2_0693	8.111e-79	275.0	COG3839@1|root,arCOG00175@2157|Archaea,2Y7MB@28890|Euryarchaeota,243UG@183968|Thermococci	183968|Thermococci	G	Part of the ABC transporter complex WtpABC involved in molybdate tungstate import. Responsible for energy coupling to the transport system (By similarity)	wtpC	-	3.6.3.55	ko:K15497	ko02010,map02010	M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5	-	-	ABC_tran,TOBE
DTH2_k127_3609962_4	403833.Pmob_0378	3.087e-62	220.0	COG0555@1|root,COG0555@2|Bacteria,2GDA4@200918|Thermotogae	200918|Thermotogae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15496	ko02010,map02010	M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5	-	-	BPD_transp_1
DTH2_k127_3634529_3	313628.LNTAR_18003	2.577e-141	458.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2,MFS_3
DTH2_k127_3634529_0	945713.IALB_1183	0.0	1226.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
DTH2_k127_3634529_2	945713.IALB_1182	3.851e-186	591.0	COG5368@1|root,COG5368@2|Bacteria	2|Bacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
DTH2_k127_3634529_1	886379.AEWI01000148_gene3364	4.879e-237	749.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,2FM8G@200643|Bacteroidia,3XJSW@558415|Marinilabiliaceae	976|Bacteroidetes	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Glycoamylase
DTH2_k127_3634529_5	1279009.ADICEAN_01863	4.793e-14	71.0	COG0446@1|root,COG0446@2|Bacteria,4NDYU@976|Bacteroidetes,47KSA@768503|Cytophagia	976|Bacteroidetes	S	PFAM RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
DTH2_k127_3637300_1	1408473.JHXO01000008_gene2784	4.596e-176	572.0	COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,2FN3A@200643|Bacteroidia	976|Bacteroidetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
DTH2_k127_3637300_0	886379.AEWI01000009_gene708	1.082e-253	792.0	COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,2FMC4@200643|Bacteroidia,3XJ58@558415|Marinilabiliaceae	976|Bacteroidetes	F	CTP synthase N-terminus	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DTH2_k127_3637300_2	509635.N824_19015	4.647e-164	529.0	COG0057@1|root,COG0057@2|Bacteria,4NG5C@976|Bacteroidetes,1IQW8@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA2	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_3637300_3	1121129.KB903370_gene8	1.483e-112	368.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia,22XDM@171551|Porphyromonadaceae	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH2_k127_3642372_1	1232410.KI421414_gene2812	3.564e-96	319.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,42NT2@68525|delta/epsilon subdivisions,2WJM5@28221|Deltaproteobacteria,43SQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ZIP Zinc transporter	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
DTH2_k127_3642372_4	247639.MGP2080_14646	6.166e-11	65.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SGHW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S protein	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
DTH2_k127_3642372_0	1121957.ATVL01000006_gene2981	1.636e-96	324.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3642372_6	313598.MED152_13334	0.0002145	49.0	2DTSH@1|root,33MGR@2|Bacteria,4NYM6@976|Bacteroidetes,1I74A@117743|Flavobacteriia,3VWV2@52959|Polaribacter	976|Bacteroidetes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
DTH2_k127_3642372_3	1122176.KB903561_gene3590	8.779e-19	90.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PSCyt1
DTH2_k127_3642372_2	1122176.KB903561_gene3589	2.358e-41	166.0	COG2010@1|root,COG2010@2|Bacteria,4PEWN@976|Bacteroidetes,1IXW6@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
DTH2_k127_3661284_0	1408473.JHXO01000011_gene3115	0.0	1087.0	COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,2FMC2@200643|Bacteroidia	976|Bacteroidetes	C	Psort location Cytoplasmic, score 9.97	-	-	2.3.1.54,4.1.1.83	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
DTH2_k127_3661284_1	1499967.BAYZ01000105_gene3488	9.281e-80	274.0	COG1180@1|root,COG1180@2|Bacteria	2|Bacteria	C	glycyl-radical enzyme activating activity	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
DTH2_k127_3667063_3	929556.Solca_1209	8.57e-81	274.0	COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,1IR1A@117747|Sphingobacteriia	976|Bacteroidetes	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
DTH2_k127_3667063_2	1121405.dsmv_2518	5.936e-116	383.0	COG0167@1|root,COG0167@2|Bacteria,1MXER@1224|Proteobacteria,42QNP@68525|delta/epsilon subdivisions,2WMX5@28221|Deltaproteobacteria,2MMTR@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH2_k127_3667063_1	880073.Calab_2890	5.523e-123	404.0	COG3616@1|root,COG3616@2|Bacteria,2NPWK@2323|unclassified Bacteria	2|Bacteria	E	Putative serine dehydratase domain	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
DTH2_k127_3667063_0	1048983.EL17_01705	3.869e-146	473.0	COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia	976|Bacteroidetes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DTH2_k127_3674724_3	1453500.AT05_05380	4.226e-40	164.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Alginate_lyase,BNR_2,Exo_endo_phos,F5_F8_type_C,Laminin_G_3,Metallophos,PA14,SASA,SLH
DTH2_k127_3674724_2	1202532.FF52_07389	8.561e-48	177.0	2A9CB@1|root,30YHC@2|Bacteria,4PCB9@976|Bacteroidetes,1ICY3@117743|Flavobacteriia,2NW38@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3674724_1	991.IW20_05405	3.445e-82	281.0	2DRR4@1|root,33CQD@2|Bacteria,4P6IM@976|Bacteroidetes,1ICNX@117743|Flavobacteriia,2NTWX@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
DTH2_k127_3674724_4	1107311.Q767_10120	1.988e-16	83.0	28IAE@1|root,2Z8D0@2|Bacteria,4NFWC@976|Bacteroidetes,1I0D2@117743|Flavobacteriia,2NTN6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3674724_0	1492737.FEM08_01180	4.668e-83	277.0	COG0281@1|root,COG0281@2|Bacteria,4PBZC@976|Bacteroidetes,1IMVT@117743|Flavobacteriia,2NVDF@237|Flavobacterium	976|Bacteroidetes	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
DTH2_k127_3688085_2	1229276.DI53_2233	1.455e-47	182.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_3688085_3	485918.Cpin_1244	6.307e-46	180.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_3688085_1	468059.AUHA01000002_gene345	4.459e-74	253.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1IP4T@117747|Sphingobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DTH2_k127_3688085_0	869213.JCM21142_41591	1.005e-102	338.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,47M21@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
DTH2_k127_3693524_1	555500.I215_00855	1.444e-55	198.0	COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,1HXPY@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM PSP1 C-terminal conserved region	fjo17	-	-	-	-	-	-	-	-	-	-	-	PSP1
DTH2_k127_3693524_2	1168034.FH5T_08795	1.446e-30	128.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,2FUJF@200643|Bacteroidia	976|Bacteroidetes	S	Gliding motility-associated lipoprotein, GldH	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
DTH2_k127_3693524_0	1121129.KB903360_gene3385	1.396e-173	564.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,2FNAU@200643|Bacteroidia,22W8Z@171551|Porphyromonadaceae	976|Bacteroidetes	M	Penicillin-binding Protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DTH2_k127_3710100_2	908612.HMPREF9720_0092	9.836e-53	190.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,2FNY1@200643|Bacteroidia	976|Bacteroidetes	G	mannose-6-phosphate isomerase, class I	-	-	-	-	-	-	-	-	-	-	-	-	ROK
DTH2_k127_3710100_1	313603.FB2170_06645	9.854e-101	340.0	COG0738@1|root,COG0738@2|Bacteria,4NEB2@976|Bacteroidetes,1IETD@117743|Flavobacteriia,2PIUE@252356|Maribacter	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DTH2_k127_3710100_0	1168034.FH5T_13325	5.109e-101	337.0	COG1940@1|root,COG1940@2|Bacteria,4NM8T@976|Bacteroidetes,2FSJS@200643|Bacteroidia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH2_k127_3723348_0	1189620.AJXL01000090_gene73	5.251e-54	192.0	COG2801@1|root,COG2801@2|Bacteria,4NI49@976|Bacteroidetes,1HWKR@117743|Flavobacteriia	976|Bacteroidetes	L	Pfam Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
DTH2_k127_3723348_1	755732.Fluta_2090	2.52e-40	170.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_3734907_2	471870.BACINT_04537	1.225e-21	95.0	COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,2FQMI@200643|Bacteroidia,4ANPJ@815|Bacteroidaceae	976|Bacteroidetes	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG3	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH2_k127_3734907_0	991.IW20_06570	1.081e-200	636.0	COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,2NV4F@237|Flavobacterium	976|Bacteroidetes	E	Histidine ammonia-lyase	hutH	-	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH2_k127_3734907_1	1121101.HMPREF1532_02370	3.478e-99	327.0	COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,2FPBQ@200643|Bacteroidia,4AKB8@815|Bacteroidaceae	976|Bacteroidetes	S	neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH2_k127_3761752_0	760192.Halhy_2916	2.868e-74	259.0	COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes	976|Bacteroidetes	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DTH2_k127_3761752_1	694427.Palpr_0277	3.163e-22	100.0	COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,2G2UX@200643|Bacteroidia,230JH@171551|Porphyromonadaceae	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
DTH2_k127_3770643_7	269797.Mbar_A1359	6.372e-16	78.0	arCOG05193@1|root,arCOG05193@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3770643_1	56780.SYN_00606	1.262e-187	604.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
DTH2_k127_3770643_3	96561.Dole_0316	6.97e-105	347.0	COG0543@1|root,COG0543@2|Bacteria,1NTWI@1224|Proteobacteria,42M66@68525|delta/epsilon subdivisions,2WJJ2@28221|Deltaproteobacteria,2MI36@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	nfnB	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DTH2_k127_3770643_2	96561.Dole_0316	6.97e-105	347.0	COG0543@1|root,COG0543@2|Bacteria,1NTWI@1224|Proteobacteria,42M66@68525|delta/epsilon subdivisions,2WJJ2@28221|Deltaproteobacteria,2MI36@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	nfnB	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DTH2_k127_3770643_0	56780.SYN_00606	1.262e-187	604.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
DTH2_k127_3770643_6	269797.Mbar_A1359	6.372e-16	78.0	arCOG05193@1|root,arCOG05193@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3775660_0	926562.Oweho_1210	1.171e-137	453.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,1HZF6@117743|Flavobacteriia,2PABI@246874|Cryomorphaceae	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_3775660_1	1121481.AUAS01000012_gene275	7.496e-70	245.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,47MVG@768503|Cytophagia	976|Bacteroidetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
DTH2_k127_3817919_0	1173027.Mic7113_0883	7.055e-130	446.0	COG3292@1|root,COG3829@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG3920@2|Bacteria,1GCAC@1117|Cyanobacteria,1HEG6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_3817919_1	1239962.C943_03902	4.971e-56	202.0	COG0457@1|root,COG0457@2|Bacteria,4NPX1@976|Bacteroidetes,47TCX@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
DTH2_k127_3817949_5	1121004.ATVC01000005_gene1342	3.533e-27	111.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2VU3F@28216|Betaproteobacteria,2KS3Z@206351|Neisseriales	206351|Neisseriales	P	Multidrug resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
DTH2_k127_3817949_1	869213.JCM21142_181	1.071e-172	553.0	2DBJC@1|root,2Z9K5@2|Bacteria,4P1C2@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolase family 47	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_47
DTH2_k127_3817949_0	1408473.JHXO01000002_gene3814	4.22e-205	661.0	COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,2G3H3@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_3817949_3	1296416.JACB01000006_gene528	3.601e-120	397.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXVI@117743|Flavobacteriia,2YHEJ@290174|Aquimarina	976|Bacteroidetes	P	Di-haem cytochrome c peroxidase	ccp	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
DTH2_k127_3817949_2	1122621.ATZA01000021_gene1747	6.703e-158	526.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia	976|Bacteroidetes	V	TIGRFAM Acidobacterial duplicated orphan permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_3817949_7	938709.AUSH02000051_gene241	1.068e-06	59.0	COG0018@1|root,COG0018@2|Bacteria	2|Bacteria	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_3817949_6	869213.JCM21142_93362	2.205e-22	107.0	COG5295@1|root,COG5295@2|Bacteria,4NMJW@976|Bacteroidetes,47XBE@768503|Cytophagia	976|Bacteroidetes	UW	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Peptidase_S74
DTH2_k127_3817949_4	1123277.KB893217_gene4553	4.578e-71	244.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,47J8X@768503|Cytophagia	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
DTH2_k127_3833133_1	1121889.AUDM01000004_gene2548	2.943e-62	233.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2NWXZ@237|Flavobacterium	976|Bacteroidetes	MO	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
DTH2_k127_3833133_3	391598.FBBAL38_01495	2.32e-21	108.0	COG1345@1|root,COG1361@1|root,COG3291@1|root,COG4733@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	LTD
DTH2_k127_3833133_0	857087.Metme_2760	1.504e-63	238.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,1T2R5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3833133_2	1122176.KB903551_gene4214	4.862e-39	153.0	2AZZY@1|root,31SA0@2|Bacteria,4NRJ3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3849120_0	1047013.AQSP01000144_gene927	2.377e-229	725.0	COG3533@1|root,COG3533@2|Bacteria,2NNW0@2323|unclassified Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
DTH2_k127_3849120_1	929703.KE386491_gene133	1.435e-46	175.0	COG1335@1|root,COG1335@2|Bacteria,4NMQE@976|Bacteroidetes,47X6J@768503|Cytophagia	976|Bacteroidetes	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DTH2_k127_3849120_2	402777.KB235898_gene5027	2.517e-31	130.0	COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH2_k127_3861315_0	1168034.FH5T_04395	5.566e-208	655.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes	976|Bacteroidetes	E	Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_3861315_5	1453500.AT05_08815	2.778e-40	163.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
DTH2_k127_3861315_3	926549.KI421517_gene2558	3.259e-100	342.0	COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH2_k127_3861315_4	1168034.FH5T_01605	8.463e-52	188.0	COG1913@1|root,COG1913@2|Bacteria,4NMI8@976|Bacteroidetes	976|Bacteroidetes	S	Zn-dependent protease	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
DTH2_k127_3861315_2	1168034.FH5T_01610	3.449e-203	640.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FMPG@200643|Bacteroidia	976|Bacteroidetes	T	acetoacetate metabolism regulatory protein AtoC K07714	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_3861315_1	1168034.FH5T_01615	1.515e-204	650.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,2FR1C@200643|Bacteroidia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_3861315_6	1168034.FH5T_01635	6.824e-29	121.0	COG0226@1|root,COG0509@1|root,COG0226@2|Bacteria,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02040,ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,ko02010,ko02020,ko05152,map00260,map00630,map01100,map01110,map01130,map01200,map02010,map02020,map05152	M00222,M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	GCV_H,PBP_like_2
DTH2_k127_3872547_2	927658.AJUM01000047_gene2884	4.541e-77	264.0	COG1018@1|root,COG1018@2|Bacteria,4PCD8@976|Bacteroidetes,2FXQD@200643|Bacteroidia,3XJNJ@558415|Marinilabiliaceae	976|Bacteroidetes	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
DTH2_k127_3872547_0	1313421.JHBV01000043_gene3023	3.867e-154	497.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1IR44@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
DTH2_k127_3872547_5	269798.CHU_1286	5.275e-08	62.0	COG3794@1|root,COG3794@2|Bacteria,4NXN9@976|Bacteroidetes	976|Bacteroidetes	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DTH2_k127_3872547_3	1286632.P278_03700	1.577e-61	217.0	COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,1I33C@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH2_k127_3872547_4	1408433.JHXV01000007_gene2924	5.395e-61	226.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.14,3.2.1.40	ko:K01183,ko:K05989	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,CBM_6,Glyco_hydro_18,Glyco_hydro_43,UnbV_ASPIC,VCBS
DTH2_k127_3872547_1	1408433.JHXV01000007_gene2926	3.321e-127	432.0	COG1629@1|root,COG4771@2|Bacteria,4NET0@976|Bacteroidetes,1HY46@117743|Flavobacteriia,2PAD5@246874|Cryomorphaceae	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
DTH2_k127_3877326_1	1034807.FBFL15_2583	3.725e-08	57.0	COG5295@1|root,COG5492@1|root,COG5295@2|Bacteria,COG5492@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia,2NUIA@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3877326_0	694427.Palpr_1088	2.816e-162	524.0	COG0526@1|root,COG0526@2|Bacteria,4PIER@976|Bacteroidetes,2G1S6@200643|Bacteroidia,23163@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_8
DTH2_k127_3889704_0	945713.IALB_1477	7.573e-47	195.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH2_k127_3889704_2	313590.MED134_09936	1.842e-09	72.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,4NQIZ@976|Bacteroidetes,1IJKK@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_3889704_1	1197477.IA57_01090	1.399e-09	72.0	COG0308@1|root,COG2374@1|root,COG3291@1|root,COG4412@1|root,COG0308@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,F5_F8_type_C,Peptidase_M1
DTH2_k127_3891086_1	485918.Cpin_0529	3.241e-43	160.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,1IPBV@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
DTH2_k127_3891086_0	1168034.FH5T_05160	0.0	1039.0	COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes	976|Bacteroidetes	C	Quinol cytochrome c oxidoreductase	nrfC	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
DTH2_k127_3930221_2	1122621.ATZA01000002_gene1608	5.202e-19	90.0	COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,1ITBU@117747|Sphingobacteriia	976|Bacteroidetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
DTH2_k127_3930221_0	1168034.FH5T_20290	3.849e-219	690.0	COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia	976|Bacteroidetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DTH2_k127_3930221_1	1227484.C471_10535	1.234e-23	109.0	COG0025@1|root,COG0569@1|root,arCOG01957@2157|Archaea,arCOG01961@2157|Archaea,2XT52@28890|Euryarchaeota,23SVP@183963|Halobacteria	183963|Halobacteria	P	COG0025 NhaP-type Na H and K H antiporters	kef1	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
DTH2_k127_3955860_4	880073.Calab_0556	2.902e-32	127.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
DTH2_k127_3955860_2	459349.CLOAM0694	3.356e-116	391.0	COG2148@1|root,COG2148@2|Bacteria,2NPSP@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_transf
DTH2_k127_3955860_3	1288963.ADIS_1763	1.219e-38	150.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,47R7B@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_3955860_1	694427.Palpr_0850	4.998e-138	457.0	28JDJ@1|root,2Z97V@2|Bacteria,4NJ02@976|Bacteroidetes,2FQ97@200643|Bacteroidia,22ZE5@171551|Porphyromonadaceae	976|Bacteroidetes	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
DTH2_k127_3955860_0	709991.Odosp_2014	5.203e-225	711.0	COG4690@1|root,COG4690@2|Bacteria,4NE03@976|Bacteroidetes,2FPSX@200643|Bacteroidia,22WBK@171551|Porphyromonadaceae	976|Bacteroidetes	M	Dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
DTH2_k127_3956059_2	203275.BFO_0180	1.551e-08	63.0	COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,2FM3I@200643|Bacteroidia,22Y6Y@171551|Porphyromonadaceae	976|Bacteroidetes	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
DTH2_k127_3956059_0	1408473.JHXO01000008_gene2880	6.942e-52	190.0	COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,2FSP8@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
DTH2_k127_3956059_1	1122179.KB890459_gene975	4.661e-39	149.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4012731_0	1121129.KB903360_gene3644	7.371e-258	811.0	COG1042@1|root,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia,22WFU@171551|Porphyromonadaceae	976|Bacteroidetes	C	CoA ligase	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DTH2_k127_4012731_2	926562.Oweho_1037	1.629e-36	143.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,2PAZS@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_4012731_1	1121890.AUDO01000001_gene680	1.27e-83	282.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia,2NSZG@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_4015751_1	880073.Calab_2857	5.361e-104	351.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DUF2808,Peptidase_S46
DTH2_k127_4015751_0	215803.DB30_1529	6.046e-143	469.0	COG2304@1|root,COG2304@2|Bacteria,1R8EZ@1224|Proteobacteria,433AE@68525|delta/epsilon subdivisions,2WYFQ@28221|Deltaproteobacteria,2YY3M@29|Myxococcales	28221|Deltaproteobacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
DTH2_k127_4015751_2	485918.Cpin_6624	8.794e-67	251.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1IXAB@117747|Sphingobacteriia	976|Bacteroidetes	T	Signal transduction histidine kinase, LytS	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12,TPR_7,TPR_8
DTH2_k127_4015751_3	1296415.JACC01000030_gene2779	2.607e-66	234.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1I0QN@117743|Flavobacteriia,2YJJY@290174|Aquimarina	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_4015751_4	1408433.JHXV01000007_gene2927	2.655e-57	212.0	2AXDY@1|root,31PDA@2|Bacteria,4PJH6@976|Bacteroidetes,1IHII@117743|Flavobacteriia,2PB08@246874|Cryomorphaceae	976|Bacteroidetes	S	HmuY protein	-	-	-	-	-	-	-	-	-	-	-	-	HmuY
DTH2_k127_4020222_0	593750.Metfor_1179	4.84e-99	332.0	arCOG04609@1|root,arCOG04609@2157|Archaea,2XVS1@28890|Euryarchaeota,2N9XU@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
DTH2_k127_4020222_1	593750.Metfor_1180	1.904e-85	288.0	arCOG04006@1|root,arCOG04006@2157|Archaea	2157|Archaea	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
DTH2_k127_4020222_2	593750.Metfor_1181	8.489e-76	265.0	COG0642@1|root,arCOG02343@1|root,arCOG02348@1|root,arCOG02343@2157|Archaea,arCOG02348@2157|Archaea,arCOG06193@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
DTH2_k127_404309_3	1122176.KB903576_gene4879	2.024e-68	251.0	COG1807@1|root,COG1807@2|Bacteria,4NQJA@976|Bacteroidetes	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_404309_0	485918.Cpin_0233	6.891e-270	854.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M
DTH2_k127_404309_2	869213.JCM21142_93910	3.682e-129	424.0	COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
DTH2_k127_404309_1	1408473.JHXO01000001_gene2292	3.376e-141	463.0	COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,2FMS1@200643|Bacteroidia	976|Bacteroidetes	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
DTH2_k127_404309_4	714943.Mucpa_1234	2.041e-66	234.0	COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1IQKA@117747|Sphingobacteriia	976|Bacteroidetes	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
DTH2_k127_4043393_0	1453500.AT05_07935	1.325e-181	587.0	COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,1HWVA@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein assembly	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
DTH2_k127_4043393_3	1313421.JHBV01000002_gene522	4.43e-101	336.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DTH2_k127_4043393_8	1408433.JHXV01000001_gene694	2.529e-41	163.0	COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1IC3X@117743|Flavobacteriia,2PB1K@246874|Cryomorphaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_4043393_4	485917.Phep_0983	1.118e-96	324.0	COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DTH2_k127_4043393_6	929703.KE386491_gene295	1.087e-79	284.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_4043393_7	929556.Solca_0558	1.104e-59	213.0	COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,1IRUD@117747|Sphingobacteriia	976|Bacteroidetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH2_k127_4043393_2	1122621.ATZA01000010_gene221	2.831e-110	364.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
DTH2_k127_4043393_9	983544.Lacal_2760	1.909e-25	114.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1HY3J@117743|Flavobacteriia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DTH2_k127_4043393_1	929556.Solca_2268	5.77e-114	380.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,4NF7T@976|Bacteroidetes,1IPSK@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
DTH2_k127_4043393_5	485918.Cpin_0710	2.841e-80	280.0	COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1IX57@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
DTH2_k127_4045182_0	385682.AFSL01000060_gene1758	4.274e-161	514.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,2FMQV@200643|Bacteroidia,3XIWM@558415|Marinilabiliaceae	976|Bacteroidetes	O	ClpX C4-type zinc finger	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DTH2_k127_4045182_1	385682.AFSL01000060_gene1759	1.354e-106	349.0	COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,2FN8E@200643|Bacteroidia,3XJUH@558415|Marinilabiliaceae	976|Bacteroidetes	OU	Clp protease	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DTH2_k127_4045182_2	926562.Oweho_2958	1.579e-38	151.0	COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,1HX7I@117743|Flavobacteriia,2PABE@246874|Cryomorphaceae	976|Bacteroidetes	O	PFAM Bacterial trigger factor protein (TF)	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
DTH2_k127_4067305_3	869213.JCM21142_52158	6.836e-52	199.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4067305_2	1235803.C825_00069	6.78e-76	263.0	COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,2FP0Q@200643|Bacteroidia,22VXF@171551|Porphyromonadaceae	976|Bacteroidetes	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
DTH2_k127_4067305_0	762903.Pedsa_1354	4.801e-87	294.0	COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,1IPGF@117747|Sphingobacteriia	976|Bacteroidetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
DTH2_k127_4067305_1	1121895.Q765_16295	1.15e-81	276.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1HYBQ@117743|Flavobacteriia,2NUWX@237|Flavobacterium	976|Bacteroidetes	EP	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DTH2_k127_407167_1	1469557.JSWF01000032_gene3162	1.725e-15	85.0	COG4886@1|root,COG4886@2|Bacteria,4PNJF@976|Bacteroidetes,1HX6N@117743|Flavobacteriia	976|Bacteroidetes	C	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH2_k127_407167_0	880073.Calab_2857	2.708e-104	349.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DUF2808,Peptidase_S46
DTH2_k127_4079505_2	592029.DDD_3488	1.1e-67	235.0	COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1HX2Z@117743|Flavobacteriia,3HK8F@363408|Nonlabens	976|Bacteroidetes	K	ECF sigma factor	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH2_k127_4079505_1	1168289.AJKI01000031_gene935	5.138e-90	301.0	COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,2FM8U@200643|Bacteroidia,3XJEV@558415|Marinilabiliaceae	976|Bacteroidetes	L	FES	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DTH2_k127_4079505_3	1453500.AT05_04940	5.01e-62	216.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia	976|Bacteroidetes	O	Thiol peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH2_k127_4079505_0	468059.AUHA01000008_gene2788	7.866e-168	532.0	COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,1INW2@117747|Sphingobacteriia	976|Bacteroidetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DTH2_k127_4079505_5	755732.Fluta_1304	7.062e-36	149.0	COG0457@1|root,COG0457@2|Bacteria,4PJHB@976|Bacteroidetes,1IMQ8@117743|Flavobacteriia,2PB7I@246874|Cryomorphaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_4079505_4	1408473.JHXO01000004_gene95	3.156e-50	183.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
DTH2_k127_4109588_1	459349.CLOAM1790	6.012e-19	96.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
DTH2_k127_4109588_2	906888.JCM19314_797	0.0003153	51.0	COG1404@1|root,COG1404@2|Bacteria,4NM0U@976|Bacteroidetes,1I0NM@117743|Flavobacteriia,3HKCK@363408|Nonlabens	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
DTH2_k127_4109588_0	1168289.AJKI01000008_gene757	5.71e-219	698.0	COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,2FMY5@200643|Bacteroidia,3XJA4@558415|Marinilabiliaceae	976|Bacteroidetes	S	ABC transporter	yheS_3	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH2_k127_4116029_1	1123373.ATXI01000008_gene1560	7.839e-151	485.0	COG2605@1|root,COG2605@2|Bacteria,2GIF3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH2_k127_4116029_0	760192.Halhy_0941	4.117e-173	552.0	COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH2_k127_4116029_2	760192.Halhy_0940	7.772e-14	71.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH2_k127_4155260_1	1353276.JADR01000007_gene1414	6.198e-101	335.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_4155260_0	1288963.ADIS_4221	6.777e-189	600.0	COG1012@1|root,COG1012@2|Bacteria,4NIC8@976|Bacteroidetes,47KER@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DTH2_k127_4155260_2	929556.Solca_2801	1.899e-61	214.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IPRD@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
DTH2_k127_4157777_2	1218103.CIN01S_20_00510	5.32e-49	177.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia,3ZS3J@59732|Chryseobacterium	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
DTH2_k127_4157777_3	1349822.NSB1T_07135	2.388e-22	97.0	COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,2FUKE@200643|Bacteroidia,22YNZ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
DTH2_k127_4157777_0	153721.MYP_3474	5.637e-68	235.0	COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,47PC6@768503|Cytophagia	976|Bacteroidetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DTH2_k127_4157777_1	1380384.JADN01000004_gene1726	9.605e-64	220.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1HX1R@117743|Flavobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
DTH2_k127_418842_2	1121012.AUKX01000012_gene2280	1.526e-88	299.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia,23H09@178469|Arenibacter	976|Bacteroidetes	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
DTH2_k127_418842_8	290397.Adeh_0995	5.433e-21	98.0	COG1832@1|root,COG1832@2|Bacteria,1NJW8@1224|Proteobacteria,42WY1@68525|delta/epsilon subdivisions,2WT3S@28221|Deltaproteobacteria,2Z10K@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
DTH2_k127_418842_3	1107311.Q767_04245	1.644e-81	276.0	COG1225@1|root,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,1HYRW@117743|Flavobacteriia,2NS87@237|Flavobacterium	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH2_k127_418842_5	1121897.AUGO01000013_gene3297	6.471e-49	181.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia,2NW2C@237|Flavobacterium	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
DTH2_k127_418842_4	1089547.KB913013_gene109	5.416e-60	210.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,47PQ5@768503|Cytophagia	976|Bacteroidetes	H	PFAM 6-pyruvoyl tetrahydropterin synthase	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_418842_7	946077.W5A_05368	2.702e-24	106.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1I3W5@117743|Flavobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DTH2_k127_418842_6	1408433.JHXV01000010_gene528	9.638e-41	154.0	COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,1I1YF@117743|Flavobacteriia,2PB2E@246874|Cryomorphaceae	976|Bacteroidetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DTH2_k127_418842_1	272559.BF9343_2403	3.102e-102	336.0	COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,2FPQ5@200643|Bacteroidia,4ANWJ@815|Bacteroidaceae	976|Bacteroidetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DTH2_k127_418842_0	1168034.FH5T_03220	1.339e-134	449.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,2FNT5@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_4189424_1	1408473.JHXO01000008_gene2886	9.067e-69	239.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_4189424_0	1168034.FH5T_08895	6.558e-108	355.0	COG3828@1|root,COG3828@2|Bacteria,4NFYI@976|Bacteroidetes,2G2RZ@200643|Bacteroidia	976|Bacteroidetes	CG	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	CARDB,Copper-bind,ThuA
DTH2_k127_4189424_2	203275.BFO_0293	1.136e-32	129.0	COG3760@1|root,COG3760@2|Bacteria,4NNW9@976|Bacteroidetes,2FSY6@200643|Bacteroidia,22Y37@171551|Porphyromonadaceae	976|Bacteroidetes	S	Aminoacyl-tRNA editing domain	proX	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
DTH2_k127_4201888_7	742725.HMPREF9450_01876	3.699e-39	148.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,2FMJH@200643|Bacteroidia,22USF@171550|Rikenellaceae	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_4201888_9	755732.Fluta_3653	9.754e-13	74.0	2A94Y@1|root,30Y99@2|Bacteria,4PC0Q@976|Bacteroidetes,1ICRR@117743|Flavobacteriia,2PBX3@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4201888_3	1349822.NSB1T_00610	8.149e-86	291.0	COG0731@1|root,COG0731@2|Bacteria,4NJEM@976|Bacteroidetes,2FMWY@200643|Bacteroidia,22WAC@171551|Porphyromonadaceae	976|Bacteroidetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_4201888_2	525373.HMPREF0766_10345	5.436e-136	441.0	COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,1INM5@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH2_k127_4201888_4	926550.CLDAP_08980	5.739e-85	293.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
DTH2_k127_4201888_8	36874.HQ34_00545	8.001e-25	111.0	COG3637@1|root,COG3637@2|Bacteria,4NV08@976|Bacteroidetes,2FYJ1@200643|Bacteroidia,230YU@171551|Porphyromonadaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_4201888_1	269798.CHU_0130	1.431e-154	498.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KGA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	amaA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_4201888_5	1168034.FH5T_11285	3.034e-69	242.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_4201888_6	411154.GFO_0183	4.211e-52	187.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DTH2_k127_4201888_0	1453500.AT05_05130	2.107e-206	676.0	COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia	976|Bacteroidetes	S	SprA protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
DTH2_k127_4211897_1	459349.CLOAM0192	5.134e-82	282.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	Autotransporter,FlgD_ig,PKD
DTH2_k127_4211897_4	1433126.BN938_0269	3.218e-27	123.0	COG0457@1|root,COG0457@2|Bacteria,4PESY@976|Bacteroidetes,2G21B@200643|Bacteroidia,22UIH@171550|Rikenellaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_4211897_0	459349.CLOAM0769	1.977e-123	420.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_4211897_6	1408473.JHXO01000001_gene2289	3.63e-14	75.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,2FUQY@200643|Bacteroidia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_4211897_7	1408473.JHXO01000001_gene2289	7.684e-14	73.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,2FUQY@200643|Bacteroidia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_4211897_8	1307759.JOMJ01000003_gene2349	3.795e-06	59.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,Response_reg
DTH2_k127_4211897_3	742725.HMPREF9450_01084	7.724e-51	197.0	COG4585@1|root,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,2FRZ7@200643|Bacteroidia,22UEE@171550|Rikenellaceae	976|Bacteroidetes	T	histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
DTH2_k127_4211897_2	1168034.FH5T_02485	1.565e-56	204.0	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,2FSDF@200643|Bacteroidia	976|Bacteroidetes	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_4211897_5	880073.Calab_0422	1.73e-19	95.0	COG0745@1|root,COG0745@2|Bacteria,2NRCE@2323|unclassified Bacteria	2|Bacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DTH2_k127_4212989_5	1408473.JHXO01000009_gene3387	4.816e-18	87.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
DTH2_k127_4212989_2	56780.SYN_00315	4.524e-71	245.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WYNI@28221|Deltaproteobacteria,2MRJ9@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
DTH2_k127_4212989_4	1163407.UU7_04167	3.285e-26	112.0	2E7UH@1|root,3329I@2|Bacteria,1NCBN@1224|Proteobacteria,1SHRS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4212989_1	880070.Cycma_2678	6.051e-90	316.0	COG0265@1|root,COG0265@2|Bacteria,4NTKB@976|Bacteroidetes	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
DTH2_k127_4212989_3	1239962.C943_02050	8.483e-53	199.0	2EAZB@1|root,33507@2|Bacteria,4NYHZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4212989_0	880526.KE386488_gene1278	2.684e-159	532.0	COG3669@1|root,COG3934@1|root,COG3669@2|Bacteria,COG3934@2|Bacteria,4NZYV@976|Bacteroidetes,2FWVF@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4243393_5	755732.Fluta_2066	1.82e-06	56.0	COG3291@1|root,COG3291@2|Bacteria,4P1A1@976|Bacteroidetes	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4243393_0	926549.KI421517_gene2416	1.119e-185	607.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH2_k127_4243393_3	1168289.AJKI01000030_gene1184	1.096e-28	117.0	COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,2G2C1@200643|Bacteroidia,3XK76@558415|Marinilabiliaceae	976|Bacteroidetes	S	RNA recognition motif	ykfA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH2_k127_4243393_2	1121129.KB903359_gene2508	5.812e-180	570.0	COG0520@1|root,COG0520@2|Bacteria,4NG72@976|Bacteroidetes,2FQA1@200643|Bacteroidia,230GJ@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_4243393_1	1121129.KB903359_gene2507	2.571e-180	574.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
DTH2_k127_4248729_3	1433126.BN938_2112	7.597e-74	251.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes,2FM8R@200643|Bacteroidia,22UPA@171550|Rikenellaceae	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
DTH2_k127_4248729_4	1121904.ARBP01000002_gene6740	4.519e-46	172.0	COG4659@1|root,COG4659@2|Bacteria,4NQKH@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
DTH2_k127_4248729_1	1408473.JHXO01000005_gene1635	3.679e-129	420.0	COG4658@1|root,COG4658@2|Bacteria,4NESE@976|Bacteroidetes,2FM2Y@200643|Bacteroidia	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
DTH2_k127_4248729_0	1168289.AJKI01000031_gene1114	3.236e-189	600.0	COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,3XJQB@558415|Marinilabiliaceae	976|Bacteroidetes	C	RnfC Barrel sandwich hybrid domain	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_7,RnfC_N,SLBB
DTH2_k127_4248729_2	869213.JCM21142_93459	1.296e-117	385.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes	976|Bacteroidetes	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
DTH2_k127_4248729_6	1313421.JHBV01000024_gene4956	5.499e-06	57.0	2DX8D@1|root,343UE@2|Bacteria,4P6Q1@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4248729_5	153721.MYP_3099	7.782e-14	82.0	COG2152@1|root,COG3291@1|root,COG2152@2|Bacteria,COG3291@2|Bacteria,4PHTS@976|Bacteroidetes,47Q40@768503|Cytophagia	976|Bacteroidetes	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_4248729_7	1163409.UUA_02206	9.757e-06	57.0	COG3055@1|root,COG3055@2|Bacteria,1NHAC@1224|Proteobacteria,1RYBY@1236|Gammaproteobacteria,1XAGU@135614|Xanthomonadales	135614|Xanthomonadales	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4255409_2	1121899.Q764_05500	2.491e-11	77.0	COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
DTH2_k127_4255409_1	1121887.AUDK01000013_gene3307	3.862e-33	148.0	COG3291@1|root,COG3291@2|Bacteria,4P5PB@976|Bacteroidetes,1IKQ7@117743|Flavobacteriia,2NSJH@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4255409_0	1500306.JQLA01000017_gene4906	2.176e-83	287.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytoene dehydrogenase	crtI	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016119,GO:0016120,GO:0016491,GO:0016627,GO:0036094,GO:0042214,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046246,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13	ko:K09835,ko:K09845,ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04787,R04798,R04800,R07512,R07517,R07520,R07523,R07534,R09691,R09692	RC01214,RC01960,RC02080,RC02088,RC02605	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
DTH2_k127_4260855_1	1237149.C900_03739	1.317e-29	122.0	COG0735@1|root,COG0735@2|Bacteria,4NT7Y@976|Bacteroidetes,47RGY@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DTH2_k127_4260855_0	648757.Rvan_0726	4.854e-143	475.0	COG0791@1|root,COG0791@2|Bacteria,1MU8A@1224|Proteobacteria,2U1XU@28211|Alphaproteobacteria,3N8B1@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4267075_1	1168034.FH5T_06025	2.422e-92	307.0	COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,2FN7D@200643|Bacteroidia	976|Bacteroidetes	G	Starch synthase, catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5
DTH2_k127_4267075_2	1229276.DI53_0867	5.959e-77	264.0	COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,1IQPW@117747|Sphingobacteriia	976|Bacteroidetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
DTH2_k127_4267075_3	1286632.P278_24850	2.506e-44	164.0	COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1I1Y4@117743|Flavobacteriia	976|Bacteroidetes	T	Molecular chaperone DnaK	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
DTH2_k127_4267075_0	1408473.JHXO01000001_gene2112	0.0	1575.0	COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia	976|Bacteroidetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DTH2_k127_4285808_2	1408433.JHXV01000004_gene3393	8.908e-74	272.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NUDC@976|Bacteroidetes,1I7JN@117743|Flavobacteriia,2PA5J@246874|Cryomorphaceae	976|Bacteroidetes	Q	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_4285808_0	1408473.JHXO01000004_gene169	2.073e-220	691.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,2FM07@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DTH2_k127_4285808_3	1237149.C900_01127	3.886e-30	125.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
DTH2_k127_4285808_1	653733.Selin_1811	8.71e-188	604.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006165,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006757,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009279,GO:0009358,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016778,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019867,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0032991,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043751,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044425,GO:0044462,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0061695,GO:0071704,GO:0071944,GO:0072521,GO:0098552,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1902494,GO:1990234	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	iSbBS512_1146.SbBS512_E2875	PP_kinase,PP_kinase_C,PP_kinase_N
DTH2_k127_4294316_1	471854.Dfer_5599	6.045e-195	625.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
DTH2_k127_4294316_3	471854.Dfer_5600	1.043e-145	476.0	COG0702@1|root,COG0702@2|Bacteria,4NHAI@976|Bacteroidetes,47Y9C@768503|Cytophagia	976|Bacteroidetes	GM	Pfam:SusD	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
DTH2_k127_4294316_2	1122226.AUHX01000001_gene533	2.582e-165	533.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1HZ2G@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
DTH2_k127_4294316_0	760192.Halhy_1114	3.741e-226	708.0	COG5520@1|root,COG5520@2|Bacteria,4NF4C@976|Bacteroidetes,1INPD@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
DTH2_k127_4294316_5	498761.HM1_2853	5.636e-40	155.0	COG1595@1|root,COG1595@2|Bacteria,1V3G9@1239|Firmicutes,24G1Y@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigZ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_4294316_4	1265505.ATUG01000002_gene1702	4.903e-95	323.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42UHV@68525|delta/epsilon subdivisions,2WQCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
DTH2_k127_4294316_7	649747.HMPREF0083_00803	1.097e-09	59.0	COG1553@1|root,COG1553@2|Bacteria,1VBNX@1239|Firmicutes,4HWVF@91061|Bacilli	91061|Bacilli	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
DTH2_k127_4294316_6	313606.M23134_03656	5.618e-25	108.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia	976|Bacteroidetes	J	PFAM translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DTH2_k127_4301242_2	485915.Dret_0526	1.336e-09	62.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,42PIX@68525|delta/epsilon subdivisions,2WJRF@28221|Deltaproteobacteria,2MA0J@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	cysT	-	-	ko:K02018,ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00189,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5,3.A.1.8	-	-	BPD_transp_1
DTH2_k127_4301242_1	1501391.LG35_07670	1.593e-88	298.0	COG1150@1|root,COG1150@2|Bacteria,4NN9R@976|Bacteroidetes,2FSAS@200643|Bacteroidia,22URS@171550|Rikenellaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_8
DTH2_k127_4301242_0	1121129.KB903359_gene2206	5.359e-145	466.0	COG2048@1|root,COG2048@2|Bacteria,4NHHH@976|Bacteroidetes,2FM47@200643|Bacteroidia,22Z84@171551|Porphyromonadaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DTH2_k127_4315266_0	313606.M23134_05475	2.72e-203	646.0	COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
DTH2_k127_4344307_1	1121094.KB894656_gene1002	5.796e-64	223.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,2FR7A@200643|Bacteroidia,4AP3D@815|Bacteroidaceae	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
DTH2_k127_4344307_0	1168034.FH5T_07850	1.136e-148	486.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,2FKYU@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_4344307_2	760192.Halhy_0635	3.823e-37	145.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1J04F@117747|Sphingobacteriia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_4351943_1	1348583.ATLH01000031_gene1954	1.633e-59	214.0	2DBMF@1|root,2Z9YG@2|Bacteria,4NPRW@976|Bacteroidetes,1I1PP@117743|Flavobacteriia,1FA6K@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4351943_3	880071.Fleli_0342	2.998e-26	113.0	2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,47Q46@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4351943_0	869213.JCM21142_41819	1.397e-189	600.0	COG0498@1|root,COG0498@2|Bacteria,4NFUZ@976|Bacteroidetes	976|Bacteroidetes	E	cysteate synthase	-	-	2.5.1.76	ko:K15527	-	-	-	-	ko00000,ko01000	-	-	-	PALP
DTH2_k127_4351943_2	309807.SRU_2346	1.946e-29	123.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
DTH2_k127_4361619_4	1408433.JHXV01000010_gene542	5.613e-48	178.0	COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia,2PAXM@246874|Cryomorphaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_4361619_0	1121904.ARBP01000004_gene1084	1.195e-305	951.0	COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,47KBV@768503|Cytophagia	976|Bacteroidetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DTH2_k127_4361619_2	648996.Theam_0663	5.375e-87	295.0	COG1218@1|root,COG1218@2|Bacteria,2G3T2@200783|Aquificae	200783|Aquificae	P	Inositol monophosphatase family	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
DTH2_k127_4361619_5	867845.KI911784_gene1941	4.964e-47	186.0	COG0545@1|root,COG0545@2|Bacteria,2GA7H@200795|Chloroflexi,3762K@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidylprolyl isomerase FKBP-type	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
DTH2_k127_4361619_6	1408433.JHXV01000010_gene505	5.882e-26	114.0	COG0545@1|root,COG0545@2|Bacteria,4NV96@976|Bacteroidetes,1IC47@117743|Flavobacteriia,2PB8G@246874|Cryomorphaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
DTH2_k127_4361619_1	1279009.ADICEAN_02596	4.429e-93	317.0	COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,47JVC@768503|Cytophagia	976|Bacteroidetes	S	phosphoesterase RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_4361619_3	1122176.KB903554_gene3833	4.053e-54	193.0	COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,1ISC1@117747|Sphingobacteriia	976|Bacteroidetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DTH2_k127_4361619_7	1120951.AUBG01000014_gene3164	2.447e-23	106.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1HYKJ@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_4362182_2	1279009.ADICEAN_01862	4.034e-176	573.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47KYY@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_4362182_0	153948.NAL212_0312	1.767e-213	670.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,372PF@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
DTH2_k127_4362182_3	694427.Palpr_1704	1.745e-100	338.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,2FN1C@200643|Bacteroidia,22X6Y@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glutamine cyclotransferase	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH2_k127_4362182_1	1122176.KB903564_gene3177	3.988e-188	612.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	2|Bacteria	M	COG5337 Spore coat assembly protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,LTD
DTH2_k127_4362182_4	272134.KB731324_gene2895	4.176e-09	60.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
DTH2_k127_4366269_1	1121889.AUDM01000003_gene2303	5.124e-80	280.0	COG4188@1|root,COG4188@2|Bacteria,4P2MC@976|Bacteroidetes,1I8M4@117743|Flavobacteriia	976|Bacteroidetes	S	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase
DTH2_k127_4366269_2	485918.Cpin_1516	2.23e-14	83.0	COG3827@1|root,COG3827@2|Bacteria,4PKT6@976|Bacteroidetes,1J0M3@117747|Sphingobacteriia	976|Bacteroidetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4366269_0	761193.Runsl_5534	4.492e-97	322.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH2_k127_4416984_6	984262.SGRA_2772	1.202e-27	112.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,1IPFB@117747|Sphingobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH2_k127_4416984_1	945713.IALB_2672	1.22e-202	638.0	COG0372@1|root,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DTH2_k127_4416984_5	1121904.ARBP01000010_gene2436	2.316e-36	153.0	COG0457@1|root,COG0642@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,4PI91@976|Bacteroidetes,47UPB@768503|Cytophagia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
DTH2_k127_4416984_7	2340.JV46_02050	5.589e-22	109.0	COG0664@1|root,COG3202@1|root,COG0664@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria	1224|Proteobacteria	CT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
DTH2_k127_4416984_4	411154.GFO_2057	4.558e-60	213.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia	976|Bacteroidetes	S	phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
DTH2_k127_4416984_0	945713.IALB_2768	1.796e-236	745.0	COG4231@1|root,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	iorA	-	1.2.7.8	ko:K00179,ko:K08941	-	M00598	-	-	br01601,ko00000,ko00002,ko00194,ko01000	-	-	-	POR_N,TPP_enzyme_C
DTH2_k127_4416984_3	1499967.BAYZ01000013_gene6442	2.155e-73	251.0	COG1014@1|root,COG1014@2|Bacteria,2NPBG@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00179,ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
DTH2_k127_4416984_2	1408473.JHXO01000001_gene2418	2.219e-96	325.0	COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,2FQ2Q@200643|Bacteroidia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_4430910_0	1168034.FH5T_20555	6.713e-163	520.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia	976|Bacteroidetes	C	CoA binding domain protein	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
DTH2_k127_4430910_2	1123008.KB905711_gene776	1.015e-59	213.0	COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,2FM8T@200643|Bacteroidia,22XNF@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,Pribosyltran
DTH2_k127_4430910_3	1168034.FH5T_06515	3.808e-08	64.0	2CEK0@1|root,321UV@2|Bacteria,4NUC9@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4271
DTH2_k127_4430910_1	1408473.JHXO01000001_gene2073	3.262e-91	305.0	COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,2FMX9@200643|Bacteroidia	976|Bacteroidetes	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
DTH2_k127_4461601_2	660470.Theba_2253	1.963e-09	66.0	28N4R@1|root,2ZBA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
DTH2_k127_4461601_0	1033743.CAES01000002_gene1810	1.41e-69	250.0	COG0715@1|root,COG0715@2|Bacteria,1TRYN@1239|Firmicutes,4I97Z@91061|Bacilli,2715F@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
DTH2_k127_4461601_1	1033743.CAES01000002_gene1809	5.944e-53	193.0	COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HDR7@91061|Bacilli,26RRZ@186822|Paenibacillaceae	91061|Bacilli	P	PFAM binding-protein-dependent transport systems inner membrane component	ssuC	-	-	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	BPD_transp_1
DTH2_k127_446501_4	1121104.AQXH01000001_gene2054	3.01e-70	244.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IQQ0@117747|Sphingobacteriia	976|Bacteroidetes	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_446501_2	471870.BACINT_02036	3.043e-108	368.0	COG1538@1|root,COG1538@2|Bacteria,4NGXM@976|Bacteroidetes,2FMD9@200643|Bacteroidia,4AKDJ@815|Bacteroidaceae	976|Bacteroidetes	MU	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_446501_3	927658.AJUM01000044_gene594	1.52e-90	301.0	COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,2FMG5@200643|Bacteroidia,3XJ04@558415|Marinilabiliaceae	976|Bacteroidetes	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
DTH2_k127_446501_1	1121859.KB890738_gene3408	1.166e-110	362.0	COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,47K4M@768503|Cytophagia	976|Bacteroidetes	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
DTH2_k127_446501_5	1197477.IA57_02565	4.485e-36	152.0	28I9R@1|root,2Z8CE@2|Bacteria,4NE54@976|Bacteroidetes,1HWWD@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
DTH2_k127_446501_6	1336803.PHEL49_1462	1.18e-14	83.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,3VW6J@52959|Polaribacter	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
DTH2_k127_446501_0	1168289.AJKI01000014_gene2076	8.564e-139	449.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,2FMD1@200643|Bacteroidia,3XJJR@558415|Marinilabiliaceae	976|Bacteroidetes	J	S4 RNA-binding domain	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_4480806_3	1178825.ALIH01000006_gene1526	8.776e-22	103.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1HXBM@117743|Flavobacteriia	976|Bacteroidetes	D	cell division protein FtsK	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH2_k127_4480806_5	925409.KI911562_gene15	6.881e-10	68.0	2DS3S@1|root,33EDT@2|Bacteria,4NY8U@976|Bacteroidetes,1IUQ6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4480806_0	1454007.JAUG01000124_gene1073	2.674e-143	471.0	COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH2_k127_4480806_1	1235803.C825_02124	1.975e-66	233.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,2FNUW@200643|Bacteroidia,22VX2@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
DTH2_k127_4480806_2	1408473.JHXO01000006_gene1176	1.877e-34	140.0	28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,2FTY0@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4480806_4	742725.HMPREF9450_01784	1.083e-17	87.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,2FP81@200643|Bacteroidia,22TZ2@171550|Rikenellaceae	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DTH2_k127_4514763_1	509191.AEDB02000055_gene3677	6.666e-17	94.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
DTH2_k127_4514763_0	929562.Emtol_1982	1.89e-28	117.0	COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,47NSY@768503|Cytophagia	976|Bacteroidetes	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
DTH2_k127_451757_1	468059.AUHA01000008_gene2728	3.611e-52	191.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
DTH2_k127_451757_2	1168034.FH5T_17545	3.218e-35	138.0	2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,2FUCD@200643|Bacteroidia	976|Bacteroidetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
DTH2_k127_451757_0	1121129.KB903367_gene2893	3.272e-126	411.0	COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,2FNDG@200643|Bacteroidia,22X4T@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DTH2_k127_4519456_1	421072.IO89_13735	6.002e-50	181.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia,3HHX0@358033|Chryseobacterium	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_4519456_2	643867.Ftrac_1201	2.21e-26	118.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PSU@768503|Cytophagia	976|Bacteroidetes	S	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_4519456_0	929556.Solca_2978	2.846e-155	496.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1IQEH@117747|Sphingobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
DTH2_k127_4530053_4	1408473.JHXO01000010_gene3548	1.29e-53	193.0	2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,2FTPA@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4530053_5	694427.Palpr_2595	1.909e-33	130.0	COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,2FTTZ@200643|Bacteroidia,22YD7@171551|Porphyromonadaceae	976|Bacteroidetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DTH2_k127_4530053_0	742725.HMPREF9450_00136	5.05e-283	887.0	COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,22U7B@171550|Rikenellaceae	976|Bacteroidetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DTH2_k127_4530053_1	867902.Ornrh_1982	8.269e-148	471.0	COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,1HWSN@117743|Flavobacteriia	976|Bacteroidetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH2_k127_4530053_2	929556.Solca_1810	1.385e-91	306.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1IPVS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DTH2_k127_4530053_6	765420.OSCT_0769	6.288e-07	62.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
DTH2_k127_4530053_3	709991.Odosp_0605	5.224e-70	241.0	COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia,22VWR@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the hydrolysis of Xaa-His dipeptides	pepD_1	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH2_k127_4536946_0	1173020.Cha6605_0968	1.476e-125	412.0	COG2267@1|root,COG2267@2|Bacteria,1G771@1117|Cyanobacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
DTH2_k127_4536946_1	1206733.BAGC01000040_gene1764	8.463e-32	129.0	2E8H6@1|root,332VD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
DTH2_k127_4538026_0	926549.KI421517_gene3604	7.496e-215	677.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia	976|Bacteroidetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
DTH2_k127_4568751_0	1408473.JHXO01000004_gene137	1.715e-175	557.0	COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia	976|Bacteroidetes	S	conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
DTH2_k127_4568751_4	1122226.AUHX01000003_gene98	8.089e-16	83.0	2AR54@1|root,31GER@2|Bacteria,4NSCR@976|Bacteroidetes,1I3RB@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_4568751_2	880073.Calab_0130	1.741e-133	431.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH2_k127_4568751_1	886379.AEWI01000049_gene3211	6.872e-173	548.0	COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia,3XJSG@558415|Marinilabiliaceae	976|Bacteroidetes	EH	Aminotransferase class-V	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
DTH2_k127_4568751_3	398720.MED217_11119	7.265e-23	103.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,1HWNH@117743|Flavobacteriia,2XIEQ@283735|Leeuwenhoekiella	976|Bacteroidetes	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH2_k127_4578355_2	1347393.HG726019_gene7818	3.592e-45	173.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,2FNAK@200643|Bacteroidia,4AN4J@815|Bacteroidaceae	976|Bacteroidetes	G	Psort location Cytoplasmic, score	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DTH2_k127_4578355_1	468059.AUHA01000003_gene1562	4.782e-116	385.0	COG0682@1|root,COG0682@2|Bacteria,4NGSG@976|Bacteroidetes,1INRB@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
DTH2_k127_4578355_4	762903.Pedsa_2484	1.126e-10	69.0	2E8SV@1|root,3333M@2|Bacteria,4P9SK@976|Bacteroidetes,1ITQN@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4293
DTH2_k127_4578355_3	1122973.KB904244_gene767	4.384e-20	100.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,22X60@171551|Porphyromonadaceae	976|Bacteroidetes	KMT	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Peptidase_M56,TonB_C
DTH2_k127_4578355_0	1408473.JHXO01000010_gene3564	2.225e-139	456.0	COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,2FMYJ@200643|Bacteroidia	976|Bacteroidetes	S	RmuC domain protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
DTH2_k127_4588758_2	313606.M23134_00108	9.452e-98	329.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,4NHFH@976|Bacteroidetes,47KN5@768503|Cytophagia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
DTH2_k127_4588758_5	558884.JRGM01000038_gene2000	6.931e-11	63.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,1RMDJ@1236|Gammaproteobacteria,1Y52Z@135624|Aeromonadales	135624|Aeromonadales	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
DTH2_k127_4588758_3	1168289.AJKI01000014_gene2101	6.968e-74	252.0	COG3155@1|root,COG3155@2|Bacteria,4NMIE@976|Bacteroidetes,2FWZJ@200643|Bacteroidia,3XIP4@558415|Marinilabiliaceae	976|Bacteroidetes	Q	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
DTH2_k127_4588758_1	946077.W5A_08939	2.884e-135	437.0	COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,1HYHD@117743|Flavobacteriia	976|Bacteroidetes	S	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
DTH2_k127_4588758_0	1313301.AUGC01000007_gene553	6.388e-166	531.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_4588758_4	1454007.JAUG01000013_gene2370	2.665e-12	68.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,1IQTX@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DTH2_k127_4593799_1	1304880.JAGB01000002_gene1751	1.438e-44	168.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,Rubrerythrin
DTH2_k127_4593799_0	1121430.JMLG01000003_gene541	2.298e-104	343.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,2613R@186807|Peptococcaceae	186801|Clostridia	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_4593799_2	565034.BHWA1_01943	7.303e-11	63.0	COG0674@1|root,COG0674@2|Bacteria,2J65R@203691|Spirochaetes	203691|Spirochaetes	C	oxidoreductase, alpha subunit	porA6	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DTH2_k127_4596731_0	388413.ALPR1_19733	3.504e-151	501.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y44@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_4596731_1	1237149.C900_01386	1.871e-57	213.0	28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,47N1W@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein SusF_SusE	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	SusE,SusF_SusE
DTH2_k127_4601627_0	706587.Desti_1366	3.822e-114	379.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MRF1@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_4601627_2	1125863.JAFN01000001_gene162	8.252e-95	321.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NI5@68525|delta/epsilon subdivisions,2WIN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
DTH2_k127_4601627_1	706587.Desti_1368	1.105e-97	326.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42N2W@68525|delta/epsilon subdivisions,2WJRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
DTH2_k127_4603105_3	945713.IALB_1719	2.021e-18	96.0	COG1404@1|root,COG4409@1|root,COG1404@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,CelD_N,FlgD_ig,Glyco_hydro_9,VCBS
DTH2_k127_4603105_0	945713.IALB_1184	4.281e-78	268.0	COG4099@1|root,COG4099@2|Bacteria	2|Bacteria	F	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Esterase_phd,Peptidase_S9
DTH2_k127_4603105_1	269797.Mbar_A1048	1.977e-58	210.0	COG1985@1|root,arCOG01489@2157|Archaea,2Y3RM@28890|Euryarchaeota,2NAWI@224756|Methanomicrobia	224756|Methanomicrobia	C	RibD C-terminal domain	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
DTH2_k127_4603105_2	1121904.ARBP01000003_gene6409	8.021e-43	164.0	2C7HJ@1|root,32NAU@2|Bacteria,4NQER@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_461442_5	1408433.JHXV01000009_gene1193	8.468e-09	60.0	COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,1HWMC@117743|Flavobacteriia,2PAPM@246874|Cryomorphaceae	976|Bacteroidetes	C	Dialkylrecorsinol condensing enzyme DarA	darA	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_461442_0	485918.Cpin_6850	1.155e-149	482.0	COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,1IPV9@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	darB	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,Thiolase_N,ketoacyl-synt
DTH2_k127_461442_3	1313421.JHBV01000138_gene1229	8.377e-25	110.0	COG0764@1|root,COG0764@2|Bacteria,4PKBK@976|Bacteroidetes,1J125@117747|Sphingobacteriia	976|Bacteroidetes	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_461442_2	1121396.KB892935_gene3856	1.131e-33	134.0	2CE7N@1|root,30Q80@2|Bacteria,1MZ6U@1224|Proteobacteria,42VBA@68525|delta/epsilon subdivisions,2WS6M@28221|Deltaproteobacteria,2MNUR@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_461442_1	376686.Fjoh_1097	3.405e-122	401.0	COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,1HXZ6@117743|Flavobacteriia,2NUPW@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
DTH2_k127_461442_4	1440053.JOEI01000002_gene3666	1.249e-10	63.0	COG1131@1|root,COG1131@2|Bacteria,2I8XU@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DTH2_k127_4622847_3	1168289.AJKI01000051_gene837	4.278e-58	206.0	COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia,3XJ8S@558415|Marinilabiliaceae	976|Bacteroidetes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DTH2_k127_4622847_2	1178825.ALIH01000008_gene809	3.079e-102	338.0	COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,1HWSV@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
DTH2_k127_4622847_1	1121931.AUHG01000019_gene3041	7.967e-141	456.0	COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia	976|Bacteroidetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
DTH2_k127_4622847_0	945713.IALB_0457	7.765e-201	636.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
DTH2_k127_4622847_4	1313172.YM304_07560	1.62e-08	59.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
DTH2_k127_4658528_3	1239962.C943_00988	7.818e-51	181.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,47T5H@768503|Cytophagia	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
DTH2_k127_4658528_0	1341181.FLJC2902T_15860	3.401e-253	787.0	COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,1HZDD@117743|Flavobacteriia,2NU65@237|Flavobacterium	976|Bacteroidetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
DTH2_k127_4658528_1	1267533.KB906736_gene1283	1.04e-119	394.0	COG0252@1|root,COG0252@2|Bacteria,3Y8XT@57723|Acidobacteria	57723|Acidobacteria	EJ	Asparaginase	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase
DTH2_k127_4658528_2	1239962.C943_00985	2.306e-69	239.0	COG3637@1|root,COG3637@2|Bacteria,4NGSV@976|Bacteroidetes	976|Bacteroidetes	M	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH2_k127_466745_3	1077285.AGDG01000031_gene3780	1.078e-106	349.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,2FMDA@200643|Bacteroidia,4AKW5@815|Bacteroidaceae	976|Bacteroidetes	V	bacteriocin export ABC transporter, lactococcin 972 group	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_466745_0	1123277.KB893172_gene540	4.389e-176	580.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_466745_2	1047013.AQSP01000114_gene680	4.197e-166	550.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_466745_1	153721.MYP_3264	1.566e-173	613.0	COG1572@1|root,COG3210@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,4NJQN@976|Bacteroidetes,47QVQ@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,IgGFc_binding,PKD,SprB,fn3
DTH2_k127_466745_5	755732.Fluta_2092	1.484e-20	110.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SprB
DTH2_k127_466745_4	742767.HMPREF9456_01856	3.014e-59	226.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia,22WF4@171551|Porphyromonadaceae	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_4672649_2	1107311.Q767_08890	1.299e-65	226.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1I16J@117743|Flavobacteriia,2NSWN@237|Flavobacterium	976|Bacteroidetes	P	permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DTH2_k127_4672649_0	926549.KI421517_gene351	5.768e-159	510.0	COG0226@1|root,COG0573@1|root,COG0226@2|Bacteria,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,47KM7@768503|Cytophagia	976|Bacteroidetes	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,PBP_like_2
DTH2_k127_4672649_1	1235803.C825_01254	1.516e-110	363.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,2FMW1@200643|Bacteroidia,22X86@171551|Porphyromonadaceae	976|Bacteroidetes	P	Bacterial extracellular solute-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_4703913_0	926562.Oweho_1756	8.023e-71	241.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1HXI3@117743|Flavobacteriia,2PAEU@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4703913_1	290512.Paes_1514	2.027e-09	61.0	2ERSA@1|root,33JBH@2|Bacteria,1FEBR@1090|Chlorobi	1090|Chlorobi	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
DTH2_k127_4733167_1	1237149.C900_02910	8.398e-39	153.0	2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4733167_0	153721.MYP_188	9.468e-179	566.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,47MXQ@768503|Cytophagia	976|Bacteroidetes	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DTH2_k127_4766063_3	694427.Palpr_2438	3.886e-86	287.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,2FM9V@200643|Bacteroidia,22WXD@171551|Porphyromonadaceae	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH2_k127_4766063_4	1185876.BN8_03106	7.609e-27	113.0	2DPSP@1|root,33387@2|Bacteria,4NVSW@976|Bacteroidetes,47T2S@768503|Cytophagia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_4766063_2	1265313.HRUBRA_01242	1.313e-92	315.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
DTH2_k127_4766063_1	247634.GPB2148_1375	4.919e-136	444.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1J4IE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
DTH2_k127_4766063_0	926562.Oweho_2197	3.792e-184	602.0	COG2132@1|root,COG3291@1|root,COG2132@2|Bacteria,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_4782297_2	1047013.AQSP01000104_gene1407	7.322e-14	73.0	28HAJ@1|root,2Z7MX@2|Bacteria,2NQBW@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4782297_1	1123008.KB905694_gene1576	3.779e-98	325.0	COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,2FRNC@200643|Bacteroidia,23086@171551|Porphyromonadaceae	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_4782297_0	177439.DP1783	1.317e-127	419.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_4782297_3	1121904.ARBP01000013_gene399	0.0002198	49.0	COG4591@1|root,COG4591@2|Bacteria,4NJRI@976|Bacteroidetes,47TBV@768503|Cytophagia	976|Bacteroidetes	M	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_4812904_2	385682.AFSL01000035_gene2906	1.521e-58	210.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae	976|Bacteroidetes	O	Trypsin	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
DTH2_k127_4812904_0	1185876.BN8_04470	4.204e-78	269.0	COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
DTH2_k127_4812904_1	927658.AJUM01000022_gene1242	8.463e-59	208.0	COG1670@1|root,COG1670@2|Bacteria,4NQ8K@976|Bacteroidetes,2FMII@200643|Bacteroidia,3XJVU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	speG	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
DTH2_k127_4812904_3	385682.AFSL01000022_gene2112	2.816e-52	191.0	COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,2FMVX@200643|Bacteroidia,3XJQ3@558415|Marinilabiliaceae	976|Bacteroidetes	S	YceG-like family	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
DTH2_k127_4816279_1	679926.Mpet_0519	5.944e-109	361.0	COG2100@1|root,arCOG00951@2157|Archaea	2157|Archaea	S	SMART Elongator protein 3 MiaB NifB	-	-	2.1.1.192	ko:K06935,ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_4816279_2	679926.Mpet_0520	9.658e-60	218.0	COG0492@1|root,arCOG01296@2157|Archaea,2XZBF@28890|Euryarchaeota	28890|Euryarchaeota	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
DTH2_k127_4816279_3	679926.Mpet_0521	2.126e-49	183.0	COG1335@1|root,arCOG01943@2157|Archaea,2Y0WZ@28890|Euryarchaeota,2NA9S@224756|Methanomicrobia	224756|Methanomicrobia	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DTH2_k127_4816279_0	1121875.KB907546_gene2216	4.347e-114	377.0	COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,1HWRE@117743|Flavobacteriia	976|Bacteroidetes	MU	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	-	-	-	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	M00641,M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
DTH2_k127_4857696_0	767817.Desgi_1747	3.162e-82	280.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp,Zn_Tnp_IS91
DTH2_k127_4876246_5	1408473.JHXO01000012_gene421	1.614e-71	250.0	COG2133@1|root,COG2133@2|Bacteria,4PMXZ@976|Bacteroidetes,2G0K9@200643|Bacteroidia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH2_k127_4876246_6	880073.Calab_1044	1.089e-66	252.0	COG0421@1|root,COG0421@2|Bacteria,2NNTV@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
DTH2_k127_4876246_0	1168034.FH5T_01600	1.567e-289	900.0	COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,2FMNU@200643|Bacteroidia	976|Bacteroidetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_4876246_3	1408473.JHXO01000005_gene1751	5.992e-142	460.0	COG1180@1|root,COG1180@2|Bacteria,4NJ18@976|Bacteroidetes,2FQZB@200643|Bacteroidia	976|Bacteroidetes	O	radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DTH2_k127_4876246_1	1121405.dsmv_0008	1.468e-199	630.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2MIET@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
DTH2_k127_4876246_2	1408473.JHXO01000011_gene3072	1.002e-194	624.0	COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,2FMUK@200643|Bacteroidia	976|Bacteroidetes	V	ABC transporter, ATP-binding protein	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH2_k127_4876246_9	1121129.KB903367_gene2734	1.159e-35	142.0	2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,2FTAK@200643|Bacteroidia,22Y3E@171551|Porphyromonadaceae	976|Bacteroidetes	S	COG NOG14473 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4876246_7	997829.HMPREF1121_00391	8.175e-58	212.0	COG0543@1|root,COG0543@2|Bacteria,4NE35@976|Bacteroidetes,2FN69@200643|Bacteroidia,22WHB@171551|Porphyromonadaceae	976|Bacteroidetes	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DTH2_k127_4876246_4	694427.Palpr_0736	2.217e-135	436.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,2FPMW@200643|Bacteroidia,22XED@171551|Porphyromonadaceae	976|Bacteroidetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH2_k127_4876246_8	1191523.MROS_1345	7.687e-41	154.0	COG2314@1|root,COG2314@2|Bacteria	2|Bacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
DTH2_k127_4876246_10	385682.AFSL01000009_gene2464	3.571e-26	110.0	2EBA7@1|root,335AR@2|Bacteria,4NX8U@976|Bacteroidetes,2G1DN@200643|Bacteroidia,3XKX2@558415|Marinilabiliaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
DTH2_k127_4876246_11	163908.KB235896_gene3711	5.31e-18	85.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH2_k127_4904791_0	333138.LQ50_19180	3.918e-48	187.0	COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZC77@1386|Bacillus	91061|Bacilli	I	Belongs to the phospholipase D family. Cardiolipin synthase subfamily	clsB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
DTH2_k127_4904791_1	1121373.KB903625_gene3159	2.145e-31	126.0	COG3279@1|root,COG3279@2|Bacteria,4NPFH@976|Bacteroidetes,47XE8@768503|Cytophagia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_4952281_3	1550091.JROE01000004_gene1509	5.579e-05	56.0	28JMZ@1|root,2Z9EE@2|Bacteria,4NKS8@976|Bacteroidetes,1ISZ3@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_4952281_1	446470.Snas_0537	7.162e-91	335.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
DTH2_k127_4952281_2	983548.Krodi_2342	2.509e-15	86.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia,37ECB@326319|Dokdonia	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_4952281_0	468059.AUHA01000003_gene1835	1.503e-244	790.0	COG1404@1|root,COG1404@2|Bacteria,4NHSQ@976|Bacteroidetes,1IWJ1@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_4998694_1	313628.LNTAR_18003	7.74e-37	148.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2,MFS_3
DTH2_k127_4998694_0	945713.IALB_1185	2.527e-151	507.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_35,Glyco_hydro_42,Glyco_hydro_42M,Sulfotransfer_2
DTH2_k127_5000811_2	1121333.JMLH01000025_gene1174	2.454e-15	83.0	COG1196@1|root,COG3325@1|root,COG3525@1|root,COG3669@1|root,COG1196@2|Bacteria,COG3325@2|Bacteria,COG3525@2|Bacteria,COG3669@2|Bacteria,1UWSE@1239|Firmicutes,3VSDW@526524|Erysipelotrichia	2|Bacteria	DG	Concanavalin A-like lectin/glucanases superfamily	hexA	-	3.2.1.4,3.2.1.45,3.2.1.51,3.2.1.52	ko:K01179,ko:K01201,ko:K01206,ko:K12373,ko:K21449	ko00500,ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00500,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	M00079	R00022,R01498,R06004,R06200,R11307,R11308,R11316	RC00049,RC00059,RC00451	ko00000,ko00001,ko00002,ko01000,ko02000,ko03110,ko04147	1.B.40.2	GH20,GH29,GH30,GH5,GH9	-	Alpha_L_fucos,Calx-beta,F5_F8_type_C,FIVAR,Glyco_hydro_20,Glyco_hydro_20b,RicinB_lectin_2
DTH2_k127_5000811_1	393921.HQ45_00900	1.599e-21	100.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,2FSTK@200643|Bacteroidia,22YUQ@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_5000811_0	1317122.ATO12_05570	1.224e-48	184.0	COG3279@1|root,COG3279@2|Bacteria,4NGX6@976|Bacteroidetes,1HYS4@117743|Flavobacteriia	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_5007008_4	4577.GRMZM2G004880_P01	6.95e-05	46.0	COG1806@1|root,2QQ1R@2759|Eukaryota,37NRA@33090|Viridiplantae,3GFS0@35493|Streptophyta,3KT19@4447|Liliopsida,3I9W0@38820|Poales	35493|Streptophyta	S	Bifunctional serine threonine kinase and phosphorylase involved in the dark light-mediated regulation of PPDK by catalyzing its phosphorylation dephosphorylation. Dark light- induced changes in stromal concentrations of the competing ADP and Pi substrates govern the direction of the reaction. In the dark, phosphorylates the catalytic intermediate of PPDK (PPDK-HisP), inactivating it. Light exposure induces the phosphorolysis reaction that reactivates PPDK	-	GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.7.11.32,2.7.4.27	ko:K20115	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
DTH2_k127_5007008_3	2340.JV46_29160	1.77e-18	89.0	COG3631@1|root,COG3631@2|Bacteria,1NA13@1224|Proteobacteria,1SSSD@1236|Gammaproteobacteria,1JB6W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
DTH2_k127_5007008_1	1454007.JAUG01000016_gene1720	7.374e-138	447.0	COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,1IP8C@117747|Sphingobacteriia	976|Bacteroidetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DTH2_k127_5007008_2	929556.Solca_2454	2.163e-53	195.0	COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,1IPFE@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
DTH2_k127_5007008_0	1453500.AT05_08315	3.926e-184	612.0	28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5008207_0	1122176.KB903541_gene212	4.618e-71	263.0	COG1680@1|root,COG3291@1|root,COG1680@2|Bacteria,COG3291@2|Bacteria,4NHZI@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_5144397_0	1047013.AQSP01000101_gene606	6.555e-112	366.0	COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria	2|Bacteria	E	Metallopeptidase family M24	pepQ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH2_k127_5144397_1	1408433.JHXV01000022_gene3142	8.927e-49	196.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5145399_3	388413.ALPR1_12585	1.791e-06	54.0	COG3085@1|root,COG3085@2|Bacteria,4P5G7@976|Bacteroidetes,47VYV@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF	-	-	-	ko:K09897	-	-	-	-	ko00000	-	-	-	DUF413
DTH2_k127_5145399_0	925409.KI911562_gene819	2.286e-63	225.0	COG0652@1|root,COG0652@2|Bacteria,4NQYP@976|Bacteroidetes	976|Bacteroidetes	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
DTH2_k127_5145399_2	484770.UFO1_0426	1.104e-20	99.0	COG1335@1|root,COG1335@2|Bacteria,1V7B8@1239|Firmicutes	1239|Firmicutes	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DTH2_k127_5145399_1	1278073.MYSTI_00905	9.246e-63	228.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,43BX1@68525|delta/epsilon subdivisions,2X77U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH2_k127_5146799_2	1313421.JHBV01000043_gene3215	2.94e-08	56.0	COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,1INNH@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DTH2_k127_5146799_1	313606.M23134_05394	3.623e-124	404.0	COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
DTH2_k127_5146799_0	1150600.ADIARSV_2887	7.304e-261	814.0	COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,1IQRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DUF4332,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_5163968_1	362418.IW19_14245	5.845e-51	192.0	COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,1HYY0@117743|Flavobacteriia,2NX4T@237|Flavobacterium	976|Bacteroidetes	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
DTH2_k127_5163968_0	1191523.MROS_0147	6.077e-91	305.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
DTH2_k127_5165737_19	471854.Dfer_4855	4.912e-15	80.0	2E0NT@1|root,32W7U@2|Bacteria,4NTP9@976|Bacteroidetes,47ST3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5165737_16	999419.HMPREF1077_02030	3.887e-41	158.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,2FMT6@200643|Bacteroidia,22Y4K@171551|Porphyromonadaceae	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_5165737_9	1121930.AQXG01000006_gene846	4.675e-79	273.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1IRXQ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
DTH2_k127_5165737_15	1120951.AUBG01000005_gene2202	2.619e-44	164.0	COG0614@1|root,COG0614@2|Bacteria,4NQYJ@976|Bacteroidetes,1I43J@117743|Flavobacteriia	976|Bacteroidetes	P	GxxExxY protein	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_5165737_0	385682.AFSL01000053_gene478	2.964e-271	845.0	COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,2FMVI@200643|Bacteroidia,3XIUZ@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
DTH2_k127_5165737_3	1408422.JHYF01000004_gene1593	1.05e-118	396.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia,36QK7@31979|Clostridiaceae	186801|Clostridia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH2_k127_5165737_2	796940.HMPREF9628_00655	6.345e-140	457.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,25SK4@186804|Peptostreptococcaceae	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH2_k127_5165737_1	1107311.Q767_10540	9.061e-202	661.0	COG4992@1|root,COG5322@1|root,COG4992@2|Bacteria,COG5322@2|Bacteria	2|Bacteria	GT	oxidoreductase activity	-	-	2.6.1.11,2.6.1.13,2.6.1.17,2.6.1.82	ko:K00819,ko:K00821,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R01155,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,G3P_acyltransf,Shikimate_DH
DTH2_k127_5165737_12	1121405.dsmv_2084	1.012e-57	215.0	COG0535@1|root,COG0535@2|Bacteria,1PNW8@1224|Proteobacteria,42YG5@68525|delta/epsilon subdivisions,2WTXF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
DTH2_k127_5165737_8	485918.Cpin_2398	2.465e-85	295.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,1IPDZ@117747|Sphingobacteriia	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_5165737_14	1191523.MROS_0749	7.204e-52	199.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DTH2_k127_5165737_11	1107311.Q767_10535	6.586e-73	258.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Acetyltransf_6,Aminotran_1_2,FemAB_like
DTH2_k127_5165737_13	1121335.Clst_1990	4.145e-57	213.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,1VRTV@1239|Firmicutes,24H21@186801|Clostridia	186801|Clostridia	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_5165737_4	1237149.C900_04326	1.26e-116	403.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH2_k127_5165737_18	385682.AFSL01000040_gene211	1.337e-15	81.0	2AISX@1|root,3199U@2|Bacteria,4NQ7A@976|Bacteroidetes,2FVPS@200643|Bacteroidia,3XK9A@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5165737_17	459349.CLOAM0099	4.571e-30	135.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
DTH2_k127_5165737_5	1048983.EL17_08735	5.852e-111	368.0	COG0501@1|root,COG0501@2|Bacteria,4PA0G@976|Bacteroidetes,47SGP@768503|Cytophagia	976|Bacteroidetes	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
DTH2_k127_5165737_10	1048983.EL17_08740	2.625e-76	260.0	COG1704@1|root,COG1704@2|Bacteria,4NMP9@976|Bacteroidetes,47RCD@768503|Cytophagia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH2_k127_5165737_7	1124780.ANNU01000017_gene1917	4.593e-108	357.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DTH2_k127_5165737_6	1392490.JHZX01000001_gene757	8.523e-111	362.0	COG3317@1|root,COG3317@2|Bacteria,4NVVX@976|Bacteroidetes,1I5WA@117743|Flavobacteriia	976|Bacteroidetes	M	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
DTH2_k127_5166380_5	761193.Runsl_3820	9.159e-05	48.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,47Y87@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_5166380_4	1124780.ANNU01000030_gene1169	3.158e-60	211.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,47P8B@768503|Cytophagia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
DTH2_k127_5166380_1	509635.N824_28700	8.64e-107	351.0	COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,1IQ0U@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH2_k127_5166380_3	1121899.Q764_11455	2.292e-67	237.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,1HXF6@117743|Flavobacteriia,2NSWX@237|Flavobacterium	976|Bacteroidetes	S	Alpha beta hydrolase	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH2_k127_5166380_2	927658.AJUM01000037_gene2262	3.416e-82	282.0	COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,2FNUF@200643|Bacteroidia,3XIQ3@558415|Marinilabiliaceae	976|Bacteroidetes	U	Sec-independent protein translocase protein (TatC)	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DTH2_k127_5166380_0	313606.M23134_05227	3.307e-181	601.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
DTH2_k127_5173192_8	1121481.AUAS01000006_gene621	1.201e-07	61.0	COG1572@1|root,COG3391@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,ILEI,Peptidase_C25
DTH2_k127_5173192_4	694427.Palpr_0624	5.453e-43	166.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_5173192_6	195103.CPF_0311	1.143e-35	139.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia,36JKZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561
DTH2_k127_5173192_3	468059.AUHA01000007_gene2695	1.165e-46	177.0	2CEQ4@1|root,2ZUK4@2|Bacteria,4NPFT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5173192_5	706587.Desti_0293	8.473e-37	143.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MS9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DTH2_k127_5173192_0	909663.KI867151_gene2966	1.993e-273	884.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1NT36@1224|Proteobacteria,42ZEC@68525|delta/epsilon subdivisions,2WU3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
DTH2_k127_5173192_1	195522.BD01_2063	1.298e-258	809.0	COG1894@1|root,COG4231@1|root,arCOG01609@2157|Archaea,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota,243V2@183968|Thermococci	183968|Thermococci	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
DTH2_k127_5173192_2	555079.Toce_0241	5.764e-55	197.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia,42ICW@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
DTH2_k127_5173192_7	745718.JADT01000014_gene128	1.314e-35	138.0	2ETTP@1|root,33MB1@2|Bacteria,4NZFX@976|Bacteroidetes,1I6T5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5177349_1	1123008.KB905711_gene819	2.435e-76	264.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,2FQTC@200643|Bacteroidia,22YWE@171551|Porphyromonadaceae	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
DTH2_k127_5177349_3	1280674.AUJK01000008_gene311	3.667e-06	57.0	COG0671@1|root,COG0671@2|Bacteria,4NKUR@976|Bacteroidetes,2FQBW@200643|Bacteroidia	976|Bacteroidetes	I	PAP2 family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,PAP2
DTH2_k127_5177349_0	686340.Metal_0653	2.671e-92	310.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RX1E@1236|Gammaproteobacteria,1XG15@135618|Methylococcales	135618|Methylococcales	IQ	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_5177349_2	1121930.AQXG01000004_gene2803	1.056e-07	53.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1IP44@117747|Sphingobacteriia	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
DTH2_k127_5231895_2	671143.DAMO_1514	1.557e-56	205.0	COG1806@1|root,COG1806@2|Bacteria,2NRN6@2323|unclassified Bacteria	2|Bacteria	S	Kinase/pyrophosphorylase	yqfL	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
DTH2_k127_5231895_3	459349.CLOAM1790	3.325e-12	78.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
DTH2_k127_5231895_0	314292.VAS14_23029	8.886e-248	774.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1XT8R@135623|Vibrionales	135623|Vibrionales	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
DTH2_k127_5231895_1	1408473.JHXO01000005_gene1467	4.212e-147	474.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH2_k127_5235018_2	1206744.BAGL01000063_gene4777	1.316e-08	66.0	COG0500@1|root,COG2226@2|Bacteria,2HEHZ@201174|Actinobacteria,4FV8J@85025|Nocardiaceae	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH2_k127_5235018_1	1124780.ANNU01000030_gene1120	2.489e-104	350.0	COG0725@1|root,COG2273@1|root,COG0725@2|Bacteria,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,47NAB@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH2_k127_5235018_0	869213.JCM21142_72890	1.289e-160	528.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47Y6I@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_5235821_14	1121012.AUKX01000017_gene3075	7.823e-20	91.0	COG0363@1|root,COG0363@2|Bacteria,4NGB9@976|Bacteroidetes,1HY6P@117743|Flavobacteriia,23G10@178469|Arenibacter	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
DTH2_k127_5235821_5	1120968.AUBX01000010_gene1433	2.515e-139	456.0	COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,47JQM@768503|Cytophagia	976|Bacteroidetes	S	PFAM Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
DTH2_k127_5235821_16	694427.Palpr_0513	4.084e-07	53.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,2FNRB@200643|Bacteroidia,22W4Z@171551|Porphyromonadaceae	976|Bacteroidetes	P	K+ potassium transporter	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
DTH2_k127_5235821_17	1189620.AJXL01000066_gene3284	7.525e-06	49.0	COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,1HX75@117743|Flavobacteriia,2NTDV@237|Flavobacterium	976|Bacteroidetes	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
DTH2_k127_5235821_13	1121875.KB907547_gene3151	2.101e-21	98.0	2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes,1I9XX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5235821_2	313603.FB2170_07914	8.395e-182	580.0	COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1HYY8@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH2_k127_5235821_1	742725.HMPREF9450_00518	5.555e-211	666.0	COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,2FNXD@200643|Bacteroidia	976|Bacteroidetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH2_k127_5235821_0	709991.Odosp_1456	4.244e-258	809.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,2FPCT@200643|Bacteroidia,22WP8@171551|Porphyromonadaceae	976|Bacteroidetes	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH2_k127_5235821_11	1408473.JHXO01000002_gene3882	1.559e-34	134.0	COG0713@1|root,COG0713@2|Bacteria,4NR5Y@976|Bacteroidetes,2G3CR@200643|Bacteroidia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH2_k127_5235821_10	313603.FB2170_07934	7.054e-39	151.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I26W@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH2_k127_5235821_8	1121875.KB907547_gene3145	9.236e-57	201.0	COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I6VR@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
DTH2_k127_5235821_4	742725.HMPREF9450_00513	5.255e-154	493.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,2FNVC@200643|Bacteroidia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH2_k127_5235821_3	313603.FB2170_07949	2.291e-176	558.0	COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
DTH2_k127_5235821_9	1121875.KB907547_gene3142	3.273e-48	177.0	COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH2_k127_5235821_6	1279009.ADICEAN_01551	5.421e-67	236.0	COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,47JYD@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH2_k127_5235821_12	1279009.ADICEAN_01552	1.314e-27	115.0	COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH2_k127_5235821_15	555779.Dthio_PD1754	3.517e-12	69.0	COG1502@1|root,COG1502@2|Bacteria,1R51A@1224|Proteobacteria,42PGS@68525|delta/epsilon subdivisions,2X5MQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
DTH2_k127_5235821_7	1123008.KB905694_gene1555	3.165e-60	212.0	COG1247@1|root,COG2141@1|root,COG1247@2|Bacteria,COG2141@2|Bacteria,4NR87@976|Bacteroidetes,2G3B2@200643|Bacteroidia,23216@171551|Porphyromonadaceae	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
DTH2_k127_5245328_2	1408473.JHXO01000010_gene3641	7.351e-34	135.0	COG0739@1|root,COG4413@1|root,COG0739@2|Bacteria,COG4413@2|Bacteria,4NJUQ@976|Bacteroidetes	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,UT
DTH2_k127_5245328_0	1239962.C943_03899	2.217e-194	616.0	COG0019@1|root,COG0019@2|Bacteria,4NGRF@976|Bacteroidetes,47U1Q@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_5245328_1	1239962.C943_03898	3.507e-65	225.0	COG0151@1|root,COG0151@2|Bacteria,4NK50@976|Bacteroidetes,47TMM@768503|Cytophagia	976|Bacteroidetes	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
DTH2_k127_5258249_2	468059.AUHA01000003_gene1835	1.631e-50	196.0	COG1404@1|root,COG1404@2|Bacteria,4NHSQ@976|Bacteroidetes,1IWJ1@117747|Sphingobacteriia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_5258249_0	468059.AUHA01000003_gene1834	1.558e-198	637.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg,TPR_12,TPR_8
DTH2_k127_5258249_1	1120965.AUBV01000013_gene1305	1.414e-62	228.0	28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BetR
DTH2_k127_5259279_0	509635.N824_18545	3.477e-262	817.0	COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia	976|Bacteroidetes	D	DNA segregation ATPase FtsK SpoIIIE and related	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH2_k127_5259279_2	1270196.JCKI01000002_gene696	3.78e-40	156.0	COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1ISK8@117747|Sphingobacteriia	976|Bacteroidetes	M	outer membrane lipoprotein carrier protein LolA	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA,LolA_2
DTH2_k127_5259279_1	504472.Slin_0974	1.525e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_5267304_1	755732.Fluta_1564	4.765e-43	166.0	2DKFZ@1|root,309D6@2|Bacteria,4PK7J@976|Bacteroidetes,1IFCY@117743|Flavobacteriia,2PB0S@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
DTH2_k127_5267304_3	1237149.C900_05458	4.058e-23	111.0	COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5267304_0	1168034.FH5T_09380	1.455e-167	537.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,2FWYQ@200643|Bacteroidia	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
DTH2_k127_5267304_4	80884.CCF45841	0.0001273	45.0	2A174@1|root,2RY03@2759|Eukaryota,3AEJQ@33154|Opisthokonta,3PC1Y@4751|Fungi,3R0XH@4890|Ascomycota,216UN@147550|Sordariomycetes,1F4P6@1028384|Glomerellales	4751|Fungi	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
DTH2_k127_5267304_2	1168034.FH5T_09390	7.749e-37	152.0	COG4251@1|root,COG4251@2|Bacteria,4PKMA@976|Bacteroidetes,2G18T@200643|Bacteroidia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Hpt,Response_reg
DTH2_k127_5270470_1	485918.Cpin_0742	1.005e-120	392.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
DTH2_k127_5270470_2	926562.Oweho_2308	2.154e-118	398.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2PBM8@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_5270470_5	1168289.AJKI01000022_gene1921	2.106e-11	71.0	29TPU@1|root,30EXX@2|Bacteria,4NPRV@976|Bacteroidetes,2FNJR@200643|Bacteroidia,3XKU7@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5270470_4	886379.AEWI01000029_gene200	1.678e-55	200.0	COG3295@1|root,COG3295@2|Bacteria,4NNGT@976|Bacteroidetes,2FNIB@200643|Bacteroidia,3XKEK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Putative PepSY_TM-like	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM_like_2
DTH2_k127_5270470_0	742817.HMPREF9449_02141	4.113e-256	809.0	COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,2FMM6@200643|Bacteroidia,22VY8@171551|Porphyromonadaceae	976|Bacteroidetes	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573,ko:K12585	ko03018,map03018	M00391	-	-	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
DTH2_k127_5270470_3	468059.AUHA01000003_gene1473	3.428e-105	347.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,1IQEC@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DTH2_k127_5270613_0	886379.AEWI01000009_gene709	4.922e-139	470.0	COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,3XIXI@558415|Marinilabiliaceae	976|Bacteroidetes	A	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
DTH2_k127_5270613_1	1158294.JOMI01000003_gene2659	1.373e-113	376.0	COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,2FNGP@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DTH2_k127_5270613_2	376686.Fjoh_1841	1.589e-108	362.0	COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1HX3P@117743|Flavobacteriia,2NT5V@237|Flavobacterium	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
DTH2_k127_5280697_1	1107311.Q767_13400	7.631e-29	118.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia,2NSNE@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
DTH2_k127_5280697_0	1150600.ADIARSV_2055	1.62e-230	731.0	COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,1IP3C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH2_k127_5286264_1	929556.Solca_2039	6.31e-290	899.0	COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,1IPWX@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
DTH2_k127_5286264_0	869213.JCM21142_3	0.0	1042.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_5295171_0	945713.IALB_1787	2.744e-154	512.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
DTH2_k127_5295171_1	945713.IALB_1788	8.761e-141	466.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5303680_1	1961.JOAK01000007_gene4191	1.035e-40	171.0	COG4257@1|root,COG4257@2|Bacteria,2GUYF@201174|Actinobacteria	201174|Actinobacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5303680_0	1048983.EL17_11630	1.376e-208	657.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,47MFP@768503|Cytophagia	976|Bacteroidetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
DTH2_k127_5303680_2	1454007.JAUG01000055_gene3320	9.764e-05	46.0	COG1409@1|root,COG2911@1|root,COG1409@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Big_5,CHU_C,DUF642,Haemagg_act,SprB
DTH2_k127_5316512_11	1408473.JHXO01000012_gene452	4.507e-12	72.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,2FV2Q@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5316512_9	926562.Oweho_0635	1.371e-30	130.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,2PB9Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
DTH2_k127_5316512_0	886379.AEWI01000008_gene686	1.739e-260	819.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia,3XIJT@558415|Marinilabiliaceae	976|Bacteroidetes	L	breast cancer carboxy-terminal domain	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH2_k127_5316512_8	755732.Fluta_1556	2.488e-33	139.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,1IMR1@117743|Flavobacteriia,2PBIA@246874|Cryomorphaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_5316512_7	1168289.AJKI01000002_gene2504	3.711e-43	168.0	COG0589@1|root,COG0589@2|Bacteria,4NWVX@976|Bacteroidetes,2FW3E@200643|Bacteroidia,3XIUB@558415|Marinilabiliaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_5316512_6	1121957.ATVL01000008_gene4469	5.241e-48	179.0	COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,47PQZ@768503|Cytophagia	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HD
DTH2_k127_5316512_5	1173023.KE650771_gene4103	3.109e-90	323.0	COG0642@1|root,COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg,dCache_1
DTH2_k127_5316512_4	869213.JCM21142_41686	4.505e-92	305.0	COG1014@1|root,COG1014@2|Bacteria,4NGWJ@976|Bacteroidetes	976|Bacteroidetes	C	2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit	porG	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
DTH2_k127_5316512_3	869213.JCM21142_41687	1.356e-118	386.0	COG1013@1|root,COG1013@2|Bacteria,4NDWF@976|Bacteroidetes	976|Bacteroidetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorA	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_5316512_2	927658.AJUM01000042_gene1757	2.25e-164	523.0	COG0674@1|root,COG0674@2|Bacteria,4NGYK@976|Bacteroidetes,2FM6R@200643|Bacteroidia,3XJ7J@558415|Marinilabiliaceae	976|Bacteroidetes	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DTH2_k127_5316512_10	1168289.AJKI01000006_gene232	8.063e-29	117.0	COG1146@1|root,COG1146@2|Bacteria,4NV91@976|Bacteroidetes,2FTXT@200643|Bacteroidia,3XKEU@558415|Marinilabiliaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21,Fer4_4
DTH2_k127_5316512_1	945713.IALB_1428	8.472e-191	604.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	alaC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DTH2_k127_5329307_0	1313301.AUGC01000001_gene1787	8.477e-192	603.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes	976|Bacteroidetes	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DTH2_k127_5329307_1	1408473.JHXO01000006_gene1183	1.411e-69	247.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,2FP24@200643|Bacteroidia	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_5329807_0	909663.KI867149_gene3445	9.486e-202	641.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2MQ7A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
DTH2_k127_5329807_2	700598.Niako_0413	1.486e-46	175.0	COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,1IRWR@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_5329807_3	1189612.A33Q_2053	6.037e-33	143.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia	976|Bacteroidetes	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_5329807_1	929556.Solca_3521	1.018e-69	241.0	COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,1IQ78@117747|Sphingobacteriia	976|Bacteroidetes	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
DTH2_k127_5339746_1	1122931.AUAE01000007_gene1185	1.644e-110	368.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22W07@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB-dependent receptor plug domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
DTH2_k127_5339746_0	929556.Solca_1173	9.09e-119	399.0	COG2913@1|root,COG2913@2|Bacteria,4PP6H@976|Bacteroidetes	976|Bacteroidetes	J	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
DTH2_k127_5341368_0	1123057.P872_15930	5.438e-167	544.0	COG0739@1|root,COG4413@1|root,COG0739@2|Bacteria,COG4413@2|Bacteria,4NJUQ@976|Bacteroidetes,47SZN@768503|Cytophagia	976|Bacteroidetes	EM	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,UT
DTH2_k127_5341368_1	1239962.C943_03901	1.609e-18	95.0	2DBUI@1|root,32TY4@2|Bacteria,4NU5S@976|Bacteroidetes,47TGU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_535002_0	760192.Halhy_1514	1.185e-122	411.0	COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,1IQKD@117747|Sphingobacteriia	976|Bacteroidetes	M	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
DTH2_k127_535002_1	1123248.KB893348_gene369	2.53e-62	227.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes	976|Bacteroidetes	H	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_5359493_2	926562.Oweho_3003	7.873e-105	348.0	COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae	976|Bacteroidetes	S	Transporter associated domain	gldE	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DTH2_k127_5359493_3	886379.AEWI01000002_gene502	2.802e-60	214.0	293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,2FUEE@200643|Bacteroidia,3XK52@558415|Marinilabiliaceae	976|Bacteroidetes	S	Gliding motility-associated lipoprotein GldD	gldD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5359493_0	1313421.JHBV01000041_gene3707	2.06e-191	624.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	cpt	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6
DTH2_k127_5359493_4	525904.Tter_1169	1.527e-54	202.0	COG0598@1|root,COG0598@2|Bacteria,2NQIW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DTH2_k127_5359493_6	1122225.AULQ01000008_gene1213	6.528e-13	79.0	COG1511@1|root,COG1511@2|Bacteria,4NRM9@976|Bacteroidetes,1I3QV@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5359493_5	1137281.D778_00468	8.932e-39	156.0	COG0515@1|root,COG5295@1|root,COG0515@2|Bacteria,COG5295@2|Bacteria,4NMJW@976|Bacteroidetes,1I19T@117743|Flavobacteriia	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,Peptidase_S74
DTH2_k127_5359493_1	929556.Solca_2600	2.891e-122	402.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1IQIZ@117747|Sphingobacteriia	976|Bacteroidetes	E	Dahp synthetase i kdsa	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
DTH2_k127_5378496_1	926549.KI421517_gene801	1.098e-23	108.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5378496_0	1408433.JHXV01000040_gene1532	2.927e-164	530.0	COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,1HX2W@117743|Flavobacteriia,2PAMH@246874|Cryomorphaceae	976|Bacteroidetes	K	PFAM Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
DTH2_k127_5378988_8	742725.HMPREF9450_00522	4.157e-19	87.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,2FP5W@200643|Bacteroidia,22USW@171550|Rikenellaceae	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DTH2_k127_5378988_1	435591.BDI_2420	1.541e-124	402.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,2FMN7@200643|Bacteroidia,22XA4@171551|Porphyromonadaceae	976|Bacteroidetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
DTH2_k127_5378988_5	1341181.FLJC2902T_24970	9.861e-60	215.0	COG0704@1|root,COG0704@2|Bacteria,4NNT5@976|Bacteroidetes,1I1UU@117743|Flavobacteriia,2NTDB@237|Flavobacterium	976|Bacteroidetes	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
DTH2_k127_5378988_2	1454007.JAUG01000002_gene2950	4.08e-93	317.0	COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,1IQ3E@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_5378988_0	1408473.JHXO01000001_gene2526	3.645e-193	609.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,2G3E3@200643|Bacteroidia	976|Bacteroidetes	E	Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine	megL	-	4.4.1.11,4.4.1.8	ko:K01760,ko:K01761	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00654,R00782,R01286,R02408,R04770,R04941	RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
DTH2_k127_5378988_6	880071.Fleli_1394	2.51e-32	134.0	2CD9I@1|root,32WZN@2|Bacteria,4NSXQ@976|Bacteroidetes,47R4I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5378988_4	643867.Ftrac_0521	8.398e-83	278.0	28N54@1|root,2ZBAD@2|Bacteria,4NM2U@976|Bacteroidetes,47JA1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5378988_3	1237149.C900_05455	1.643e-92	311.0	28Y2X@1|root,2ZJYG@2|Bacteria,4NN0R@976|Bacteroidetes,47PI8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5378988_7	1121904.ARBP01000003_gene6417	3.19e-23	103.0	COG4886@1|root,COG4886@2|Bacteria,4NHJ3@976|Bacteroidetes,47NN3@768503|Cytophagia	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_5397433_2	926562.Oweho_3335	2.604e-21	98.0	COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,1I465@117743|Flavobacteriia,2PBWQ@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
DTH2_k127_5397433_0	1408473.JHXO01000006_gene1385	2.355e-129	425.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FWBI@200643|Bacteroidia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_5397433_1	869213.JCM21142_52254	9.643e-98	334.0	28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,47UN2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5103
DTH2_k127_5397433_3	1124780.ANNU01000064_gene437	9.006e-19	88.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,47M23@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
DTH2_k127_5404418_2	935837.JAEK01000042_gene3784	4.471e-07	51.0	2A61F@1|root,30UTS@2|Bacteria,1UB8J@1239|Firmicutes,4IMMA@91061|Bacilli,1ZKEM@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5404418_1	1191523.MROS_1472	1.235e-33	136.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
DTH2_k127_5404418_0	945713.IALB_0147	2.122e-46	190.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
DTH2_k127_5407539_1	1041930.Mtc_2235	1.002e-18	86.0	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota,2N9BJ@224756|Methanomicrobia	224756|Methanomicrobia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	aor-2	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
DTH2_k127_5407539_0	96561.Dole_0225	1.013e-85	300.0	COG0318@1|root,COG0318@2|Bacteria,1NRF1@1224|Proteobacteria,42ZBQ@68525|delta/epsilon subdivisions,2WUGE@28221|Deltaproteobacteria,2MMKI@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
DTH2_k127_5408092_0	1227739.Hsw_3933	3.07e-233	740.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47TCZ@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_5408092_1	1279009.ADICEAN_03468	5.719e-208	656.0	COG3263@1|root,COG3263@2|Bacteria,4NFNS@976|Bacteroidetes,47P2K@768503|Cytophagia	976|Bacteroidetes	P	TrkA-C domain	cvrA	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
DTH2_k127_5408092_2	1168289.AJKI01000053_gene785	1.754e-28	116.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,2FM8D@200643|Bacteroidia,3XJA3@558415|Marinilabiliaceae	976|Bacteroidetes	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
DTH2_k127_5408409_4	472759.Nhal_2488	7.974e-32	129.0	COG4932@1|root,COG4932@2|Bacteria,1P8KK@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5408409_10	1250278.JQNQ01000001_gene3254	4.331e-13	82.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Reprolysin_4,TSP_3
DTH2_k127_5408409_11	411154.GFO_2063	1.169e-09	69.0	2DR29@1|root,339VD@2|Bacteria,4NZEP@976|Bacteroidetes,1I852@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5408409_2	1121403.AUCV01000012_gene4109	1.502e-70	270.0	COG1075@1|root,COG1075@2|Bacteria,1QD4I@1224|Proteobacteria,435MR@68525|delta/epsilon subdivisions,2X9BC@28221|Deltaproteobacteria,2MNSY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5408409_5	1463820.JOGW01000022_gene310	1.403e-24	121.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	nanM	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005623,GO:0016853,GO:0016854,GO:0016857,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	5.1.3.24	ko:K13276,ko:K17948	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Kelch_1,Kelch_4,Kelch_6,PKD,Peptidase_M6,Peptidase_S8
DTH2_k127_5408409_6	1464048.JNZS01000011_gene4918	2.452e-18	101.0	COG1404@1|root,COG2755@1|root,COG3209@1|root,COG4775@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,COG3209@2|Bacteria,COG4775@2|Bacteria,2GK5H@201174|Actinobacteria,4D9TR@85008|Micromonosporales	201174|Actinobacteria	EGM	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3
DTH2_k127_5408409_1	446470.Snas_0537	2.288e-95	347.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
DTH2_k127_5408409_9	926562.Oweho_2108	1.193e-13	85.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2PBG6@246874|Cryomorphaceae	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PKD
DTH2_k127_5408409_12	1120965.AUBV01000010_gene2754	1.412e-09	72.0	COG2911@1|root,COG3210@1|root,COG5492@1|root,COG5563@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,COG5563@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
DTH2_k127_5408409_8	1121957.ATVL01000006_gene2766	1.901e-15	91.0	COG3291@1|root,COG3291@2|Bacteria,4NJHV@976|Bacteroidetes,47R0V@768503|Cytophagia	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH2_k127_5408409_0	485918.Cpin_3759	5.303e-107	356.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DTH2_k127_5408409_13	1237149.C900_05136	0.0002798	43.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,47KZ2@768503|Cytophagia	976|Bacteroidetes	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DTH2_k127_5410878_4	760192.Halhy_0935	1.89e-06	50.0	COG2304@1|root,COG2304@2|Bacteria,4NFQQ@976|Bacteroidetes,1IQP4@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM N-terminal double-transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
DTH2_k127_5410878_3	1122226.AUHX01000011_gene450	1.152e-29	127.0	COG0221@1|root,COG0221@2|Bacteria,4NPTA@976|Bacteroidetes,1I2GY@117743|Flavobacteriia	976|Bacteroidetes	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
DTH2_k127_5410878_2	1449126.JQKL01000008_gene287	3.454e-69	239.0	COG1335@1|root,COG1335@2|Bacteria,1V5TQ@1239|Firmicutes,24IZ9@186801|Clostridia	186801|Clostridia	Q	Isochorismatase family	entB	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DTH2_k127_5410878_0	1137281.D778_00836	0.0	1062.0	COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,1HWVT@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH2_k127_5410878_1	331678.Cphamn1_0006	2.091e-166	532.0	COG0426@1|root,COG0426@2|Bacteria,1FDX4@1090|Chlorobi	1090|Chlorobi	C	PFAM beta-lactamase domain protein	-	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
DTH2_k127_5415522_1	755732.Fluta_2740	3.893e-40	161.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_5415522_0	755732.Fluta_2741	1.058e-250	802.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4PIMA@976|Bacteroidetes,1ICC3@117743|Flavobacteriia,2PBZQ@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug
DTH2_k127_5425447_0	485915.Dret_1270	1.177e-41	162.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_5425447_1	935845.JADQ01000084_gene68	1.314e-21	100.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,4HNC2@91061|Bacilli,26XID@186822|Paenibacillaceae	91061|Bacilli	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH2_k127_5442546_1	1121904.ARBP01000002_gene6764	3.455e-240	756.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MXA@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N
DTH2_k127_5442546_0	742817.HMPREF9449_02821	0.0	1050.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,22W91@171551|Porphyromonadaceae	976|Bacteroidetes	P	CarboxypepD_reg-like domain	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_5442546_2	760192.Halhy_0390	4.066e-204	647.0	COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1IREB@117747|Sphingobacteriia	976|Bacteroidetes	M	RagB SusD domain protein	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
DTH2_k127_5448799_1	313594.PI23P_07015	3.175e-77	265.0	COG5383@1|root,COG5383@2|Bacteria,4NGFT@976|Bacteroidetes,1I068@117743|Flavobacteriia,3VX1A@52959|Polaribacter	976|Bacteroidetes	S	DUF1338	-	-	-	-	-	-	-	-	-	-	-	-	DUF1338
DTH2_k127_5448799_0	1123234.AUKI01000017_gene2613	3.294e-90	308.0	COG0095@1|root,COG0095@2|Bacteria,4NE5F@976|Bacteroidetes,1HZU2@117743|Flavobacteriia	976|Bacteroidetes	H	Bacterial lipoate protein ligase C-terminus	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
DTH2_k127_5448799_2	641491.DND132_0758	6.313e-56	203.0	2EN5S@1|root,33FTP@2|Bacteria,1N0PI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
DTH2_k127_5450233_1	468059.AUHA01000006_gene2860	1.21e-97	324.0	COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,1IRJS@117747|Sphingobacteriia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH2_k127_5450233_2	762903.Pedsa_2251	8.104e-49	177.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH2_k127_5450233_0	1237149.C900_03657	0.0	1277.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia	976|Bacteroidetes	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
DTH2_k127_5451085_1	385682.AFSL01000053_gene460	2.049e-137	459.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia,3XIZ5@558415|Marinilabiliaceae	976|Bacteroidetes	T	GHKL domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_5451085_2	929556.Solca_1434	7.475e-109	364.0	COG1979@1|root,COG1979@2|Bacteria,4NF1D@976|Bacteroidetes,1IRIF@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-containing alcohol dehydrogenase	bdhA	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
DTH2_k127_5451085_0	411477.PARMER_01351	1.19e-161	517.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,2FPBU@200643|Bacteroidia,22W20@171551|Porphyromonadaceae	976|Bacteroidetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DTH2_k127_5451085_3	709991.Odosp_2965	1.711e-60	211.0	COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae	976|Bacteroidetes	GM	NAD dependent epimerase dehydratase family	ltd	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH2_k127_5461913_1	203119.Cthe_0582	9.258e-45	185.0	COG4191@1|root,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,24A78@186801|Clostridia,3WHKR@541000|Ruminococcaceae	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
DTH2_k127_5461913_0	889378.Spiaf_1705	4.455e-109	368.0	COG2204@1|root,COG2204@2|Bacteria,2J9VS@203691|Spirochaetes	203691|Spirochaetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_5461913_2	525898.Sdel_1579	0.0001112	51.0	COG0745@1|root,COG0745@2|Bacteria,1Q5DC@1224|Proteobacteria,42R42@68525|delta/epsilon subdivisions,2YNXG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_5463845_0	459349.CLOAM1725	1.046e-12	82.0	COG1361@1|root,COG1404@1|root,COG2957@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37,3.5.3.12	ko:K08589,ko:K10536,ko:K20276	ko00330,ko01100,ko01503,ko02024,map00330,map01100,map01503,map02024	-	R01416	RC00177	ko00000,ko00001,ko01000,ko01002	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,Reprolysin_4,SLH,fn3
DTH2_k127_5468331_1	1121904.ARBP01000011_gene1448	7.761e-99	339.0	COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47KYP@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	aefA	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
DTH2_k127_5468331_0	1239962.C943_00431	2.535e-166	536.0	COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,47MC5@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DTH2_k127_5468331_2	1469557.JSWF01000019_gene437	5.344e-09	57.0	COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes	976|Bacteroidetes	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
DTH2_k127_547688_1	1121272.KB903249_gene1580	0.0001913	53.0	COG3386@1|root,COG3386@2|Bacteria,2GNV1@201174|Actinobacteria,4DD3S@85008|Micromonosporales	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
DTH2_k127_547688_0	1499967.BAYZ01000095_gene4113	1.173e-12	72.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	hoxX	-	-	ko:K19640	-	-	-	-	ko00000,ko02022	-	-	-	ECH_1,Formyl_trans_C,Formyl_trans_N
DTH2_k127_5481014_1	1047013.AQSP01000073_gene1092	1.107e-12	81.0	COG1305@1|root,COG3391@1|root,COG1305@2|Bacteria,COG3391@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Transglut_core
DTH2_k127_5481014_2	760192.Halhy_5597	0.000961	52.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44,Glyco_hydro_cc,Laminin_G_3,PA14
DTH2_k127_5481014_0	926550.CLDAP_17040	1.283e-67	252.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DTH2_k127_5508606_2	679199.HMPREF9332_01811	0.0005611	51.0	2DBHI@1|root,2Z9A6@2|Bacteria,4PJDY@976|Bacteroidetes,2G271@200643|Bacteroidia,1WDM4@1283313|Alloprevotella	976|Bacteroidetes	S	Outer membrane protein SusF_SusE	-	-	-	-	-	-	-	-	-	-	-	-	SusE,SusF_SusE
DTH2_k127_5508606_1	485918.Cpin_4979	1.92e-30	134.0	COG5492@1|root,COG5492@2|Bacteria,4NT99@976|Bacteroidetes	976|Bacteroidetes	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,CBM9_1,DM13,DUF4979,Pectate_lyase_3
DTH2_k127_5508606_0	945713.IALB_3109	2.65e-39	162.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_5514405_3	1244869.H261_21124	6.531e-11	63.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,2U2F7@28211|Alphaproteobacteria,2JPK6@204441|Rhodospirillales	204441|Rhodospirillales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH2_k127_5514405_4	756499.Desde_0739	1.668e-05	51.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,24BHT@186801|Clostridia,261MX@186807|Peptococcaceae	186801|Clostridia	I	PFAM Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_5514405_0	1168034.FH5T_08385	9.387e-165	546.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH2_k127_5514405_2	1408813.AYMG01000014_gene1704	2.206e-42	164.0	COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia	976|Bacteroidetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
DTH2_k127_5514405_1	1408473.JHXO01000001_gene2016	4.599e-85	304.0	COG4485@1|root,COG4485@2|Bacteria,4P3PY@976|Bacteroidetes	976|Bacteroidetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5531598_0	1127692.HMPREF9075_01869	5.68e-191	608.0	COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IJAQ@117743|Flavobacteriia,1EQDU@1016|Capnocytophaga	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_5531598_1	945713.IALB_1743	1.498e-45	178.0	2BZ4V@1|root,33Z6S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5531598_3	945713.IALB_1742	8.8e-28	118.0	2BTXK@1|root,32P5R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5534932_0	926562.Oweho_2044	1.42e-54	216.0	2EW37@1|root,33PGF@2|Bacteria,4P22D@976|Bacteroidetes,1I7PK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5552647_1	517418.Ctha_2133	2.93e-128	419.0	COG0399@1|root,COG0399@2|Bacteria,1FEWK@1090|Chlorobi	1090|Chlorobi	H	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_5552647_0	313606.M23134_06289	2.719e-206	667.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_5586057_0	385682.AFSL01000088_gene883	1.004e-159	507.0	COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,2FMUP@200643|Bacteroidia,3XJPH@558415|Marinilabiliaceae	976|Bacteroidetes	M	RmlD substrate binding domain	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_5586057_2	1123037.AUDE01000022_gene1467	1.406e-47	182.0	COG4424@1|root,COG4424@2|Bacteria,4NKZ1@976|Bacteroidetes,1I12S@117743|Flavobacteriia	976|Bacteroidetes	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
DTH2_k127_5586057_1	1323663.AROI01000024_gene1535	1.621e-80	278.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_5626443_1	247490.KSU1_C0538	4.936e-123	400.0	COG1741@1|root,COG1741@2|Bacteria,2IXVU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
DTH2_k127_5626443_0	1122605.KB893645_gene1122	1.554e-183	580.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_5626443_2	929713.NIASO_10100	2.192e-25	113.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1IPSQ@117747|Sphingobacteriia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01965,ko:K01968	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00373,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
DTH2_k127_5627850_0	1191523.MROS_1301	5.326e-57	203.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DTH2_k127_5627850_1	945713.IALB_1477	1.505e-33	149.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH2_k127_5630641_1	1396141.BATP01000019_gene1622	1.932e-77	279.0	COG1874@1|root,COG3345@1|root,COG1874@2|Bacteria,COG3345@2|Bacteria,46XPU@74201|Verrucomicrobia,2IWC9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
DTH2_k127_5630641_0	457424.BFAG_04036	5.828e-103	342.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia,4AN0P@815|Bacteroidaceae	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DTH2_k127_5664306_2	1121405.dsmv_2975	1.915e-13	70.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MIUW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH2_k127_5664306_1	435591.BDI_2002	4.032e-51	186.0	COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,2FM7Q@200643|Bacteroidia,22Y0H@171551|Porphyromonadaceae	976|Bacteroidetes	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_5664306_0	1408473.JHXO01000006_gene1402	5.018e-72	263.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane protein, OMP85 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_5674644_0	452637.Oter_2137	7.052e-56	207.0	COG2006@1|root,COG2006@2|Bacteria,46U2P@74201|Verrucomicrobia,3K77Y@414999|Opitutae	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH2_k127_5674644_1	1237149.C900_04983	8.141e-47	181.0	COG4978@1|root,COG4978@2|Bacteria	2|Bacteria	-	-	MA20_43725	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like
DTH2_k127_5674644_2	992406.RIA_2042	1.397e-33	130.0	COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia	976|Bacteroidetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
DTH2_k127_5685483_3	1168034.FH5T_04010	3.394e-39	149.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,2FNA8@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DTH2_k127_5685483_0	391596.PBAL39_04833	7.192e-308	961.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,1IP28@117747|Sphingobacteriia	976|Bacteroidetes	C	malic enzyme	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
DTH2_k127_5685483_1	1453500.AT05_00665	2.392e-137	444.0	COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia	976|Bacteroidetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH2_k127_5685483_2	1121859.KB890759_gene1960	1.251e-78	269.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,47M2I@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
DTH2_k127_5709141_3	1224318.DT73_21885	5.557e-15	78.0	2B2HD@1|root,31V2D@2|Bacteria,1N0R5@1224|Proteobacteria,1S7IS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5709141_2	1313421.JHBV01000138_gene1211	1.099e-39	154.0	298PT@1|root,2ZVU7@2|Bacteria,4NPTP@976|Bacteroidetes,1IY91@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5709141_1	261292.Nit79A3_1025	4.426e-83	281.0	COG3409@1|root,COG3409@2|Bacteria,1NEG1@1224|Proteobacteria,2VV5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan	-	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_46,PG_binding_1
DTH2_k127_5709141_0	85643.Tmz1t_4068	5.753e-97	337.0	2CC4B@1|root,3267W@2|Bacteria,1RJP5@1224|Proteobacteria,2VU2U@28216|Betaproteobacteria,2KZ3X@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5709141_4	882083.SacmaDRAFT_0674	1.983e-05	49.0	COG1463@1|root,COG1463@2|Bacteria,2GMU6@201174|Actinobacteria,4E0CZ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Virulence factor Mce family protein	mce4C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	Mce4_CUP1,MlaD
DTH2_k127_5714004_2	1341181.FLJC2902T_31040	1.446e-15	78.0	COG0702@1|root,COG0702@2|Bacteria,4NICI@976|Bacteroidetes,1IIU7@117743|Flavobacteriia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
DTH2_k127_5714004_0	1123248.KB893328_gene923	2.972e-170	541.0	COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1IRNA@117747|Sphingobacteriia	976|Bacteroidetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DTH2_k127_5714004_1	1121875.KB907549_gene1998	1.741e-98	327.0	COG0428@1|root,COG0428@2|Bacteria,4NHR7@976|Bacteroidetes,1HZWS@117743|Flavobacteriia	976|Bacteroidetes	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
DTH2_k127_5717703_2	693979.Bache_2853	6.332e-74	254.0	COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,2FMA4@200643|Bacteroidia,4ANMW@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the synthesis of activated sulfate	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
DTH2_k127_5717703_1	927658.AJUM01000043_gene810	3.676e-153	488.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,2FM2X@200643|Bacteroidia,3XJ9I@558415|Marinilabiliaceae	976|Bacteroidetes	EH	Phosphoadenosine phosphosulfate reductase family	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH2_k127_5717703_0	472759.Nhal_2421	3.351e-199	627.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1WWRV@135613|Chromatiales	135613|Chromatiales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
DTH2_k127_5717703_4	468059.AUHA01000004_gene2153	1.57e-41	158.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,1ITZ8@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
DTH2_k127_5717703_5	667014.Thein_0728	2.059e-34	135.0	2DNS7@1|root,32YWC@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_5717703_3	760192.Halhy_3411	1.917e-62	220.0	COG0640@1|root,COG0640@2|Bacteria,4NS23@976|Bacteroidetes,1IT8B@117747|Sphingobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
DTH2_k127_5725494_0	1168034.FH5T_14410	1.543e-200	633.0	COG0621@1|root,COG0621@2|Bacteria,4NZXZ@976|Bacteroidetes,2FX31@200643|Bacteroidia	976|Bacteroidetes	J	TRAM domain	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DTH2_k127_5725494_1	385682.AFSL01000026_gene681	6.246e-157	506.0	COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,2FM1T@200643|Bacteroidia,3XJD0@558415|Marinilabiliaceae	976|Bacteroidetes	J	Uncharacterized protein family UPF0004	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
DTH2_k127_5725494_2	880071.Fleli_1610	1.266e-131	432.0	COG1752@1|root,COG1752@2|Bacteria,4NPBQ@976|Bacteroidetes,47QP5@768503|Cytophagia	976|Bacteroidetes	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_5725494_3	1453500.AT05_07140	1.727e-16	79.0	COG1350@1|root,COG1350@2|Bacteria,4PKSY@976|Bacteroidetes,1IK1C@117743|Flavobacteriia	976|Bacteroidetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH2_k127_5745784_2	1124780.ANNU01000020_gene3299	7.539e-10	64.0	COG0782@1|root,COG0782@2|Bacteria,4PK2Q@976|Bacteroidetes,47R5Y@768503|Cytophagia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5745784_1	1408473.JHXO01000005_gene1652	1.228e-25	114.0	2AIA7@1|root,318R1@2|Bacteria,4NQPK@976|Bacteroidetes,2FPYF@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF5063
DTH2_k127_5745784_0	886379.AEWI01000009_gene719	1.371e-234	745.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
DTH2_k127_5756205_1	876269.ARWA01000001_gene1525	4.406e-91	307.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,3NC06@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.12.1.2,1.6.5.3	ko:K00335,ko:K18005	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
DTH2_k127_5756205_3	381666.PHG089	2.35e-63	225.0	COG3383@1|root,COG3383@2|Bacteria,1MXTC@1224|Proteobacteria,2WGYK@28216|Betaproteobacteria,1KIJI@119060|Burkholderiaceae	28216|Betaproteobacteria	F	4Fe-4S single cluster domain	hoxU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18006	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
DTH2_k127_5756205_2	697282.Mettu_1512	3.683e-72	247.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,1XDM0@135618|Methylococcales	135618|Methylococcales	C	PFAM NADH ubiquinone	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
DTH2_k127_5756205_0	497321.C664_02175	9.99e-194	615.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,2KVAX@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
DTH2_k127_5756205_4	349521.HCH_00104	2.372e-14	74.0	COG0680@1|root,COG0680@2|Bacteria,1MZE1@1224|Proteobacteria,1SB0K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	hydrogenase maturation protease	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5758448_1	547042.BACCOPRO_00150	3.326e-48	181.0	COG3118@1|root,COG3118@2|Bacteria,4NQNX@976|Bacteroidetes,2FSPP@200643|Bacteroidia,4ANK1@815|Bacteroidaceae	976|Bacteroidetes	O	Psort location Cytoplasmic, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
DTH2_k127_5758448_2	694427.Palpr_2538	1.499e-35	139.0	COG3677@1|root,COG3677@2|Bacteria,4NHKN@976|Bacteroidetes,2FS7V@200643|Bacteroidia	976|Bacteroidetes	L	SPTR Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
DTH2_k127_5758448_0	1279009.ADICEAN_03128	2.702e-87	297.0	COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
DTH2_k127_5758448_3	36874.HQ34_03735	7.396e-24	104.0	COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,2FTW4@200643|Bacteroidia	976|Bacteroidetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
DTH2_k127_5758448_4	1137281.D778_01485	1.99e-22	111.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_5758448_5	319236.JCM19294_2252	2.2e-08	66.0	COG5295@1|root,COG5295@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia,3HK7B@363408|Nonlabens	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5758786_0	926562.Oweho_3343	2.454e-74	270.0	COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,1HYJH@117743|Flavobacteriia,2PAXR@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4131)	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
DTH2_k127_5758786_1	1168034.FH5T_17650	5.19e-41	157.0	COG1595@1|root,COG1595@2|Bacteria,4NVR6@976|Bacteroidetes	976|Bacteroidetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH2_k127_5763891_0	153721.MYP_448	1.292e-162	520.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KDQ@768503|Cytophagia	976|Bacteroidetes	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
DTH2_k127_5763891_2	1121413.JMKT01000010_gene907	3.969e-21	98.0	COG4875@1|root,COG4875@2|Bacteria,1RFS2@1224|Proteobacteria	1224|Proteobacteria	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_5763891_1	459349.CLOAM1725	1.263e-33	151.0	COG1361@1|root,COG1404@1|root,COG2957@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.22.37,3.5.3.12	ko:K08589,ko:K10536,ko:K20276	ko00330,ko01100,ko01503,ko02024,map00330,map01100,map01503,map02024	-	R01416	RC00177	ko00000,ko00001,ko01000,ko01002	-	-	-	PAD_porph,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,Reprolysin_4,SLH,fn3
DTH2_k127_5763891_3	404380.Gbem_1922	2.6e-19	104.0	COG1361@1|root,COG3055@1|root,COG3420@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
DTH2_k127_5767210_1	1168034.FH5T_01210	2.319e-60	219.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_5767210_0	1313421.JHBV01000015_gene5746	3.827e-73	257.0	COG1215@1|root,COG1215@2|Bacteria,4NN4F@976|Bacteroidetes,1J064@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_5783797_2	926562.Oweho_2105	2.096e-22	106.0	COG3291@1|root,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia,2PC60@246874|Cryomorphaceae	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_5783797_1	929556.Solca_3723	2.279e-79	272.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1INQF@117747|Sphingobacteriia	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
DTH2_k127_5783797_0	1191523.MROS_2082	4.894e-95	327.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH2_k127_579354_1	1120966.AUBU01000001_gene715	2.714e-34	139.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,47KJ6@768503|Cytophagia	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
DTH2_k127_579354_2	694427.Palpr_1518	5.189e-18	87.0	COG0607@1|root,COG0607@2|Bacteria,4NXGV@976|Bacteroidetes,2FUKK@200643|Bacteroidia,22YWS@171551|Porphyromonadaceae	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_579354_0	1168289.AJKI01000014_gene2068	1.119e-259	807.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FPY6@200643|Bacteroidia,3XJAQ@558415|Marinilabiliaceae	976|Bacteroidetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
DTH2_k127_5796819_0	1313301.AUGC01000010_gene889	1.804e-141	464.0	COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes	976|Bacteroidetes	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
DTH2_k127_5796819_1	755732.Fluta_1592	4.768e-116	398.0	COG3291@1|root,COG3291@2|Bacteria,4PP0G@976|Bacteroidetes,1IKDG@117743|Flavobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
DTH2_k127_5796819_2	313606.M23134_00106	1.568e-17	97.0	COG1649@1|root,COG3291@1|root,COG4733@1|root,COG1649@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NJK3@976|Bacteroidetes,47TYM@768503|Cytophagia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43
DTH2_k127_5812838_0	316067.Geob_0004	2.455e-244	772.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_5813494_4	350688.Clos_1115	5.418e-09	61.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	yrkH	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
DTH2_k127_5813494_2	869213.JCM21142_52355	4.636e-33	131.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,47W3A@768503|Cytophagia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DTH2_k127_5813494_6	1347342.BN863_26810	1.232e-06	62.0	COG3291@1|root,COG3291@2|Bacteria,4NUFV@976|Bacteroidetes,1HZH1@117743|Flavobacteriia	976|Bacteroidetes	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_5813494_3	1048983.EL17_00280	4.938e-09	70.0	COG3291@1|root,COG3291@2|Bacteria,4NJAF@976|Bacteroidetes,47P0M@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_5813494_0	927658.AJUM01000034_gene301	1.361e-36	160.0	COG4704@1|root,COG4704@2|Bacteria,4NUMP@976|Bacteroidetes,2G1EU@200643|Bacteroidia,3XM0J@558415|Marinilabiliaceae	976|Bacteroidetes	S	Fibrobacter succinogenes major domain (Fib_succ_major)	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Fib_succ_major
DTH2_k127_5813494_5	1191523.MROS_1538	8.054e-08	64.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SLH
DTH2_k127_5813494_1	1123276.KB893290_gene5205	1.595e-36	151.0	COG1577@1|root,COG1874@1|root,COG2374@1|root,COG2706@1|root,COG4625@1|root,COG4886@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG2374@2|Bacteria,COG2706@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,4NI5S@976|Bacteroidetes,47THH@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Calx-beta,Exo_endo_phos,He_PIG,LTD,VCBS
DTH2_k127_5814317_0	880074.BARVI_03030	3.603e-151	496.0	COG1874@1|root,COG1874@2|Bacteria,4PNM8@976|Bacteroidetes,2G105@200643|Bacteroidia,22YWU@171551|Porphyromonadaceae	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5841082_2	760192.Halhy_1516	3.502e-14	72.0	COG1943@1|root,COG1943@2|Bacteria,4NTCS@976|Bacteroidetes,1ITNU@117747|Sphingobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH2_k127_5841082_0	485918.Cpin_1178	2.142e-86	297.0	COG2972@1|root,COG2972@2|Bacteria,4NHYI@976|Bacteroidetes,1J05C@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase internal region	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
DTH2_k127_5841082_1	1144313.PMI10_02463	3.773e-35	136.0	COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,1HZ0N@117743|Flavobacteriia,2NTKW@237|Flavobacterium	976|Bacteroidetes	T	LytTR family transcriptional regulator	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_5910594_0	926562.Oweho_3031	2.964e-95	338.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2PBRD@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM Peptidase family M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_5923215_0	1166018.FAES_1548	1.921e-262	828.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47Y6I@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_5923215_1	1166018.FAES_1549	3.851e-168	542.0	COG0702@1|root,COG0702@2|Bacteria,4PKHQ@976|Bacteroidetes,47XXB@768503|Cytophagia	976|Bacteroidetes	GM	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
DTH2_k127_5923215_4	1270196.JCKI01000009_gene3353	7.685e-75	263.0	COG4733@1|root,COG4733@2|Bacteria,4NPYJ@976|Bacteroidetes,1IV35@117747|Sphingobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH2_k127_5923215_2	1166018.FAES_1551	2.534e-155	501.0	COG1653@1|root,COG1653@2|Bacteria,4NJ41@976|Bacteroidetes	976|Bacteroidetes	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
DTH2_k127_5923215_3	665571.STHERM_c01980	3.012e-114	376.0	COG3842@1|root,COG3842@2|Bacteria,2J5T3@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
DTH2_k127_5937085_1	1123288.SOV_1c00130	0.0002486	54.0	COG1538@1|root,COG1538@2|Bacteria,1TQ0W@1239|Firmicutes,4H3MR@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_5937085_0	944480.ATUV01000001_gene988	1.143e-08	68.0	COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,437DK@68525|delta/epsilon subdivisions,2WSN1@28221|Deltaproteobacteria,2M76S@213113|Desulfurellales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_5944990_0	313606.M23134_05335	1.899e-120	416.0	COG1372@1|root,COG4447@1|root,COG5184@1|root,COG5492@1|root,COG1372@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NEZQ@976|Bacteroidetes,47PGJ@768503|Cytophagia	976|Bacteroidetes	G	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Sortilin-Vps10
DTH2_k127_5944990_2	485917.Phep_1067	5.218e-26	122.0	COG1044@1|root,COG1044@2|Bacteria,4P2I7@976|Bacteroidetes,1IY65@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5944990_4	700598.Niako_4283	1.75e-12	79.0	COG5295@1|root,COG5295@2|Bacteria,4NJTK@976|Bacteroidetes,1IVP5@117747|Sphingobacteriia	976|Bacteroidetes	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH2_k127_5944990_1	945713.IALB_3109	6.306e-82	289.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_5944990_3	1292020.H483_0115975	1.483e-18	88.0	2EG8Z@1|root,332XF@2|Bacteria,2GTHG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5944990_5	929556.Solca_1767	3.745e-05	46.0	295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,1IZ1W@117747|Sphingobacteriia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5958740_5	1121481.AUAS01000004_gene1263	9.66e-43	159.0	COG4104@1|root,COG4104@2|Bacteria,4NSCZ@976|Bacteroidetes,47RD1@768503|Cytophagia	976|Bacteroidetes	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
DTH2_k127_5958740_2	745718.JADT01000012_gene961	1.082e-94	333.0	COG3501@1|root,COG3501@2|Bacteria,4NFNC@976|Bacteroidetes,1HYZA@117743|Flavobacteriia	976|Bacteroidetes	S	Rhs element Vgr protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
DTH2_k127_5958740_6	991.IW20_02175	7.187e-31	125.0	2BVGE@1|root,32QVA@2|Bacteria,4NQM7@976|Bacteroidetes,1I3K9@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5958740_4	983544.Lacal_2260	3.952e-46	169.0	2BVGE@1|root,3233K@2|Bacteria,4NPJD@976|Bacteroidetes,1IKBZ@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5958740_1	1121875.KB907546_gene2411	3.137e-217	682.0	2CCAQ@1|root,2Z8M7@2|Bacteria,4NE4K@976|Bacteroidetes,1HYKG@117743|Flavobacteriia	976|Bacteroidetes	S	Family of unknown function (DUF5458)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5458
DTH2_k127_5958740_3	983544.Lacal_2242	6.917e-52	187.0	COG3516@1|root,COG3516@2|Bacteria,4NMKM@976|Bacteroidetes,1I281@117743|Flavobacteriia	976|Bacteroidetes	S	type VI secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	T6SS_VipA
DTH2_k127_5958740_0	761193.Runsl_5211	1.645e-280	884.0	COG0542@1|root,COG0542@2|Bacteria,4NFMK@976|Bacteroidetes,47KA5@768503|Cytophagia	976|Bacteroidetes	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DTH2_k127_5981537_1	1434325.AZQN01000004_gene1512	2.867e-47	182.0	COG0823@1|root,COG0823@2|Bacteria,4NQIN@976|Bacteroidetes,47QV9@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_5981537_0	869213.JCM21142_72809	2.448e-226	721.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,47MI6@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 2	csxA_2	-	3.2.1.165,3.2.1.25	ko:K01192,ko:K15855	ko00511,ko00520,ko01100,ko04142,map00511,map00520,map01100,map04142	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH2_k127_5990952_2	1121859.KB890738_gene3087	4.397e-176	561.0	COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,47P2J@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DTH2_k127_5990952_1	1121129.KB903359_gene1233	4.073e-179	569.0	COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,2G0CZ@200643|Bacteroidia,2325F@171551|Porphyromonadaceae	976|Bacteroidetes	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DTH2_k127_5990952_0	709991.Odosp_0293	1.749e-247	779.0	COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,2FMEX@200643|Bacteroidia,22X3H@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
DTH2_k127_5990952_4	1408433.JHXV01000005_gene2237	1.202e-84	298.0	2ENP2@1|root,33GAE@2|Bacteria,4NZIT@976|Bacteroidetes,1I8VS@117743|Flavobacteriia,2PB29@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_5990952_5	1121904.ARBP01000006_gene3933	1.715e-62	226.0	COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,47MHM@768503|Cytophagia	976|Bacteroidetes	M	Lipid A biosynthesis acyltransferase	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
DTH2_k127_5990952_3	929562.Emtol_2961	1.61e-118	390.0	COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,47K2G@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
DTH2_k127_5990952_6	153721.MYP_257	6.864e-50	181.0	COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,47PUX@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
DTH2_k127_5992334_0	945713.IALB_3135	7.004e-115	383.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	VPA0558	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH2_k127_5992334_1	1408473.JHXO01000005_gene1472	2.585e-92	309.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,2FSCB@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
DTH2_k127_5992334_2	1408473.JHXO01000005_gene1471	5.567e-35	140.0	COG1309@1|root,COG1309@2|Bacteria,4NW3D@976|Bacteroidetes	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH2_k127_6011089_4	1565314.OA34_12700	5.677e-92	310.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2YNH0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DTH2_k127_6011089_1	886379.AEWI01000029_gene218	8.684e-165	522.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,2FM8V@200643|Bacteroidia,3XJ2G@558415|Marinilabiliaceae	976|Bacteroidetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_6011089_0	1453505.JASY01000001_gene3269	9.504e-211	663.0	COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia,2NYQ9@237|Flavobacterium	976|Bacteroidetes	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH2_k127_6011089_6	865938.Weevi_0039	4.717e-07	58.0	COG3391@1|root,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,1I6BT@117743|Flavobacteriia	976|Bacteroidetes	DZ	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TIG
DTH2_k127_6011089_2	1121101.HMPREF1532_02660	1.937e-137	464.0	arCOG08054@1|root,2Z8AD@2|Bacteria,4NJ65@976|Bacteroidetes,2FP4Z@200643|Bacteroidia,4ANWG@815|Bacteroidaceae	976|Bacteroidetes	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	-	-	-	-	-	-	-	-	-	-	-	Cthe_2159
DTH2_k127_6011089_3	742766.HMPREF9455_00755	1.375e-108	365.0	COG1470@1|root,COG1470@2|Bacteria,4NGFF@976|Bacteroidetes,2FN5A@200643|Bacteroidia,22X2I@171551|Porphyromonadaceae	976|Bacteroidetes	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_6011089_7	880073.Calab_1973	8.229e-05	56.0	COG2911@1|root,COG4447@1|root,COG2911@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	CBM_X2,fn3
DTH2_k127_6011089_5	59374.Fisuc_1605	2.156e-44	184.0	COG0406@1|root,COG4704@1|root,COG0406@2|Bacteria,COG4704@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	Fib_succ_major,His_Phos_1
DTH2_k127_6024923_2	1265505.ATUG01000001_gene3448	4.89e-50	180.0	COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,42TGE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	MA20_27600	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6024923_7	1408433.JHXV01000025_gene4032	0.0001994	54.0	COG3540@1|root,COG3540@2|Bacteria,4NH1W@976|Bacteroidetes,1HXGC@117743|Flavobacteriia,2PAGY@246874|Cryomorphaceae	976|Bacteroidetes	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
DTH2_k127_6024923_6	1122176.KB903587_gene4373	7.119e-33	147.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	CHU_C,PKD,Peptidase_M43,SprB
DTH2_k127_6024923_5	1237149.C900_00381	3.586e-37	148.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47PTY@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_6024923_4	1128421.JAGA01000002_gene1145	1.746e-41	166.0	COG1575@1|root,COG1575@2|Bacteria,2NPNN@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	menA	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737	UbiA
DTH2_k127_6024923_3	931276.Cspa_c37570	5.039e-46	173.0	COG1266@1|root,COG1266@2|Bacteria,1VEJJ@1239|Firmicutes,24EDW@186801|Clostridia,36GT3@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DTH2_k127_6024923_0	459349.CLOAM0030	1.079e-70	252.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.17.22	ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Cellulase,DUF4859,F5_F8_type_C,FlgD_ig
DTH2_k127_6091488_0	880526.KE386488_gene1229	1.979e-155	497.0	COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,2FNKW@200643|Bacteroidia,22UAV@171550|Rikenellaceae	976|Bacteroidetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_6091488_1	1121129.KB903359_gene2337	2.856e-43	162.0	COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,2FPJM@200643|Bacteroidia,22W6B@171551|Porphyromonadaceae	976|Bacteroidetes	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DTH2_k127_6092039_0	1168034.FH5T_01700	2.801e-167	537.0	COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes	976|Bacteroidetes	E	Saccharopine dehydrogenase	-	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DTH2_k127_6092039_1	1499967.BAYZ01000013_gene6446	8.449e-44	163.0	COG0686@1|root,COG0686@2|Bacteria,2NNTE@2323|unclassified Bacteria	2|Bacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	sdh	-	1.5.1.7,1.5.1.8,1.5.1.9	ko:K00290,ko:K14157	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_6120341_0	926562.Oweho_1705	1.761e-202	649.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia,2PA9W@246874|Cryomorphaceae	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
DTH2_k127_6146005_1	1121481.AUAS01000015_gene2297	1.739e-61	217.0	COG4565@1|root,COG4584@1|root,COG4565@2|Bacteria,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,47MFD@768503|Cytophagia	976|Bacteroidetes	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_7,rve
DTH2_k127_6146005_0	1121481.AUAS01000015_gene2296	1.299e-96	322.0	COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,47P7E@768503|Cytophagia	976|Bacteroidetes	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
DTH2_k127_6146005_2	485917.Phep_3668	3.779e-10	60.0	COG0464@1|root,COG0464@2|Bacteria,4NFWG@976|Bacteroidetes,1IR7U@117747|Sphingobacteriia	976|Bacteroidetes	O	AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
DTH2_k127_6154994_0	1121097.JCM15093_2587	7.825e-132	427.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,2FM6N@200643|Bacteroidia,4AKJJ@815|Bacteroidaceae	976|Bacteroidetes	V	Psort location Cytoplasmic, score 9.12	yxlF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_6154994_1	1235803.C825_04292	1.517e-85	289.0	COG1277@1|root,COG1277@2|Bacteria,4NGAT@976|Bacteroidetes,2FP5B@200643|Bacteroidia,22WDU@171551|Porphyromonadaceae	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH2_k127_6171556_3	880073.Calab_0032	1.728e-101	347.0	COG3408@1|root,COG3408@2|Bacteria,2NPYR@2323|unclassified Bacteria	2|Bacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,GDE_C,GDE_N_bis
DTH2_k127_6171556_1	1408473.JHXO01000011_gene3168	2.894e-200	637.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,4NI1Z@976|Bacteroidetes,2FUDK@200643|Bacteroidia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
DTH2_k127_6171556_0	1047013.AQSP01000029_gene2170	1.573e-216	684.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH2_k127_6171556_2	1453500.AT05_00205	6.28e-120	400.0	COG2819@1|root,COG2819@2|Bacteria,4PMBF@976|Bacteroidetes,1IJQK@117743|Flavobacteriia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH2_k127_6171556_7	338963.Pcar_1863	6.206e-27	115.0	COG0824@1|root,COG0824@2|Bacteria,1PF7Z@1224|Proteobacteria,42SV4@68525|delta/epsilon subdivisions,2WPY3@28221|Deltaproteobacteria,43SSY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
DTH2_k127_6171556_5	1254432.SCE1572_16370	1.023e-70	261.0	2A79N@1|root,30W69@2|Bacteria,1PHGN@1224|Proteobacteria,42ZJ6@68525|delta/epsilon subdivisions,2WUWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_6171556_4	1499967.BAYZ01000187_gene3876	3.32e-97	327.0	COG0697@1|root,COG0697@2|Bacteria,2NQTD@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	yoaV3	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_6171556_6	1408473.JHXO01000001_gene2266	5.554e-47	175.0	COG1670@1|root,COG1670@2|Bacteria,4NQ4Z@976|Bacteroidetes,2FSTX@200643|Bacteroidia	976|Bacteroidetes	J	Acetyltransferase, gnat family	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
DTH2_k127_6171556_9	335543.Sfum_4035	0.0001854	49.0	COG5513@1|root,COG5513@2|Bacteria,1Q83W@1224|Proteobacteria,42XPU@68525|delta/epsilon subdivisions,2WT8K@28221|Deltaproteobacteria,2MQR1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Chagasin family peptidase inhibitor I42	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Inhibitor_I42
DTH2_k127_6178694_0	945713.IALB_0185	6.836e-50	197.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH2_k127_6182594_5	1168034.FH5T_07425	3.519e-63	224.0	COG0664@1|root,COG0664@2|Bacteria,4NRFI@976|Bacteroidetes,2G2ZU@200643|Bacteroidia	976|Bacteroidetes	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
DTH2_k127_6182594_3	1168289.AJKI01000015_gene2177	4.769e-105	349.0	COG1145@1|root,COG1145@2|Bacteria,4NI4X@976|Bacteroidetes,2FN3Z@200643|Bacteroidia,3XJS3@558415|Marinilabiliaceae	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
DTH2_k127_6182594_7	1121097.JCM15093_2260	2.151e-37	143.0	COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,2FT3R@200643|Bacteroidia,4ARM3@815|Bacteroidaceae	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH2_k127_6182594_1	927658.AJUM01000042_gene1639	1.643e-158	509.0	COG2461@1|root,COG2461@2|Bacteria,4NJQA@976|Bacteroidetes,2FMK7@200643|Bacteroidia,3XKFV@558415|Marinilabiliaceae	976|Bacteroidetes	S	PAS domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
DTH2_k127_6182594_6	385682.AFSL01000014_gene2770	9.125e-45	169.0	COG4309@1|root,COG4309@2|Bacteria,4NQP0@976|Bacteroidetes,2FUI1@200643|Bacteroidia,3XKFI@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
DTH2_k127_6182594_2	927658.AJUM01000022_gene1018	8.992e-136	449.0	COG3182@1|root,COG3182@2|Bacteria,4NJ7N@976|Bacteroidetes,2FPKX@200643|Bacteroidia,3XKDY@558415|Marinilabiliaceae	976|Bacteroidetes	S	PepSY domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
DTH2_k127_6182594_4	1168034.FH5T_18035	1.017e-78	268.0	COG3005@1|root,COG3005@2|Bacteria,4NK7R@976|Bacteroidetes,2FPIJ@200643|Bacteroidia	976|Bacteroidetes	C	cytochrome c nitrate reductase, small subunit	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
DTH2_k127_6182594_0	1168289.AJKI01000015_gene2180	1.264e-180	571.0	COG3303@1|root,COG3303@2|Bacteria,4NG0P@976|Bacteroidetes,2FP37@200643|Bacteroidia,3XKSC@558415|Marinilabiliaceae	976|Bacteroidetes	P	Cytochrome c552	nrfA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
DTH2_k127_6185670_0	1150600.ADIARSV_0334	3.127e-97	323.0	COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,1IPJX@117747|Sphingobacteriia	976|Bacteroidetes	C	Fe-S oxidoreductase	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
DTH2_k127_6185670_1	1122176.KB903535_gene2022	4.434e-59	233.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_6185670_3	673862.BABL1_707	5.153e-41	175.0	COG1520@1|root,COG2706@1|root,COG1520@2|Bacteria,COG2706@2|Bacteria,1QV8R@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase activity	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,DUF4347,HYR,VCBS
DTH2_k127_6185670_2	1484460.JSWG01000011_gene1705	1.371e-57	212.0	COG3391@1|root,COG3391@2|Bacteria,4PKUJ@976|Bacteroidetes,1IJFM@117743|Flavobacteriia	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6198551_21	926559.JoomaDRAFT_2004	1.848e-05	54.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,1HWP9@117743|Flavobacteriia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
DTH2_k127_6198551_1	1124780.ANNU01000045_gene2306	1.262e-240	764.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,47MF3@768503|Cytophagia	976|Bacteroidetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH2_k127_6198551_2	1408473.JHXO01000004_gene14	6.638e-220	695.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,2FQ2H@200643|Bacteroidia	976|Bacteroidetes	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
DTH2_k127_6198551_6	1408473.JHXO01000010_gene3699	1.515e-143	463.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FPA0@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
DTH2_k127_6198551_4	1168034.FH5T_10700	1.276e-150	487.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,2FM5B@200643|Bacteroidia	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	macB_3	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_6198551_7	1408473.JHXO01000010_gene3697	1.912e-138	452.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FNZ2@200643|Bacteroidia	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_6198551_10	385682.AFSL01000105_gene84	3.716e-102	337.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,2FNRG@200643|Bacteroidia,3XJ9H@558415|Marinilabiliaceae	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_6198551_12	1237149.C900_04332	1.53e-90	316.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia	976|Bacteroidetes	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
DTH2_k127_6198551_0	1123008.KB905699_gene1915	1.228e-249	789.0	COG1164@1|root,COG1164@2|Bacteria,4NFV3@976|Bacteroidetes,2FMG8@200643|Bacteroidia,22XF5@171551|Porphyromonadaceae	976|Bacteroidetes	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6198551_14	1408473.JHXO01000005_gene1831	1.253e-74	260.0	COG1520@1|root,COG1520@2|Bacteria,4PNAK@976|Bacteroidetes	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6198551_15	1168034.FH5T_18890	5.256e-74	265.0	COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,2FWGT@200643|Bacteroidia	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	Peptidase_M56,TonB_C
DTH2_k127_6198551_18	1168034.FH5T_18880	4.94e-45	166.0	COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,2FTZK@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
DTH2_k127_6198551_16	203119.Cthe_2213	7.868e-59	209.0	COG4843@1|root,COG4843@2|Bacteria,1V5RI@1239|Firmicutes,25DG5@186801|Clostridia	186801|Clostridia	S	UPF0316 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
DTH2_k127_6198551_11	755732.Fluta_0377	4.343e-95	330.0	COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,1HY7G@117743|Flavobacteriia,2PAKB@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH2_k127_6198551_5	1408473.JHXO01000010_gene3660	2.608e-147	483.0	COG0348@1|root,COG0437@1|root,COG0348@2|Bacteria,COG0437@2|Bacteria,4NHSX@976|Bacteroidetes,2FN5F@200643|Bacteroidia	976|Bacteroidetes	C	Psort location CytoplasmicMembrane, score	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
DTH2_k127_6198551_8	1191523.MROS_1652	3.316e-122	400.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,TAT_signal
DTH2_k127_6198551_17	1121890.AUDO01000009_gene157	1.354e-50	183.0	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,1I1DP@117743|Flavobacteriia,2NW3U@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH2_k127_6198551_9	929556.Solca_3331	5.622e-116	385.0	COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,1IR75@117747|Sphingobacteriia	976|Bacteroidetes	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH2_k127_6198551_13	1232437.KL662016_gene1079	9.332e-83	286.0	COG3568@1|root,COG3568@2|Bacteria,1RJX3@1224|Proteobacteria,42XMX@68525|delta/epsilon subdivisions,2WTAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_6198551_3	1313301.AUGC01000007_gene678	9.75e-200	634.0	COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes	976|Bacteroidetes	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_6198551_19	1237149.C900_02194	2.504e-24	111.0	COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
DTH2_k127_6198551_20	1173023.KE650771_gene545	9.916e-20	96.0	COG3247@1|root,COG3247@2|Bacteria,1G652@1117|Cyanobacteria,1JJJ3@1189|Stigonemataceae	1117|Cyanobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
DTH2_k127_6198794_1	1121904.ARBP01000017_gene5127	7.848e-36	145.0	2DP7Y@1|root,330X4@2|Bacteria,4NUP0@976|Bacteroidetes,47XV3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6198794_0	927658.AJUM01000022_gene1202	3.413e-114	375.0	COG1554@1|root,COG1554@2|Bacteria,4NFYU@976|Bacteroidetes,2FPE9@200643|Bacteroidia,3XKH9@558415|Marinilabiliaceae	976|Bacteroidetes	G	COG NOG26513 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6241736_1	1123008.KB905694_gene1719	5.084e-12	68.0	COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,2FPEJ@200643|Bacteroidia,22YY7@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	arsM	-	2.1.1.137,2.1.1.79	ko:K00574,ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_31
DTH2_k127_6241736_0	204669.Acid345_4167	8.379e-66	240.0	COG1520@1|root,COG1520@2|Bacteria,3Y2H2@57723|Acidobacteria,2JM3H@204432|Acidobacteriia	204432|Acidobacteriia	S	PQQ-like domain	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	PQQ_3
DTH2_k127_6241736_2	1198452.Jab_1c10720	1.996e-05	51.0	COG2203@1|root,COG3292@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMUZ@28216|Betaproteobacteria,475JP@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Reg_prop,Y_Y_Y
DTH2_k127_6255309_1	1047013.AQSP01000081_gene101	8.706e-27	110.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_6255309_2	926549.KI421517_gene3562	8.81e-05	56.0	COG1404@1|root,COG2911@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG4935@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
DTH2_k127_6255309_0	880073.Calab_1858	3.346e-126	433.0	COG1361@1|root,COG4447@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,TM_helix
DTH2_k127_6255944_5	1487923.DP73_13075	7.956e-27	111.0	COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,24QZG@186801|Clostridia,265X2@186807|Peptococcaceae	186801|Clostridia	GM	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.219,1.1.1.412	ko:K00091,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DTH2_k127_6255944_0	768704.Desmer_2116	5.776e-150	485.0	COG0535@1|root,COG0535@2|Bacteria,1U17E@1239|Firmicutes,25M2T@186801|Clostridia,262BB@186807|Peptococcaceae	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DTH2_k127_6255944_3	1487923.DP73_13110	5.161e-122	400.0	COG0382@1|root,COG0382@2|Bacteria,1VQU0@1239|Firmicutes,24ZBN@186801|Clostridia	186801|Clostridia	H	PFAM UbiA prenyltransferase family	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DTH2_k127_6255944_1	768704.Desmer_2109	1.742e-134	441.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
DTH2_k127_6255944_7	563040.Saut_0567	1.456e-06	54.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2YPX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_6255944_2	768704.Desmer_2111	1.187e-129	425.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,261UX@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_6255944_4	768704.Desmer_2112	9.995e-70	250.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_6255944_6	1307761.L21SP2_0404	5.65e-09	63.0	2EUPK@1|root,33N5D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6259177_0	600809.BPLAN_488	2.789e-80	274.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1II1X@117743|Flavobacteriia,3IVM7@39782|Blattabacteriaceae	976|Bacteroidetes	I	Potassium transporter peripheral membrane component	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_627370_3	1250006.JHZZ01000001_gene234	1.33e-45	171.0	COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia,3VV44@52959|Polaribacter	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_627370_4	1408324.JNJK01000002_gene3380	2.697e-32	136.0	COG2746@1|root,COG2746@2|Bacteria,1VD7S@1239|Firmicutes,24RTX@186801|Clostridia,27K26@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Aminoglycoside 3-N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Antibiotic_NAT
DTH2_k127_627370_5	1157635.KB892068_gene5420	1.309e-05	53.0	COG0454@1|root,COG0456@2|Bacteria,2H48U@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,NUDIX
DTH2_k127_627370_1	573370.DMR_p1_00620	2.109e-114	385.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WNBU@28221|Deltaproteobacteria,2M8AN@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	TIGRFAM Amino acid adenylation	-	-	-	ko:K04786,ko:K13611	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
DTH2_k127_627370_2	1453500.AT05_02205	1.67e-97	332.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	pelE	-	3.4.11.10,3.4.11.6,4.2.2.2	ko:K01728,ko:K19701	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_2,CBM_6,Pec_lyase,Prenyltrans
DTH2_k127_627370_0	714943.Mucpa_1900	8.11e-177	571.0	COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,1IQ35@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DTH2_k127_6276006_0	59374.Fisuc_2815	1.243e-23	114.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
DTH2_k127_6276006_1	313606.M23134_04413	2.159e-12	79.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,47TYP@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
DTH2_k127_6284006_0	459349.CLOAM0304	3.739e-143	491.0	COG1404@1|root,COG1404@2|Bacteria,2NQX6@2323|unclassified Bacteria	2|Bacteria	O	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
DTH2_k127_6289504_0	153721.MYP_1271	8.441e-42	177.0	COG5492@1|root,COG5492@2|Bacteria,4PKMF@976|Bacteroidetes,47QU9@768503|Cytophagia	976|Bacteroidetes	N	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6289504_1	880073.Calab_1225	1.2e-35	156.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,PD40
DTH2_k127_6289504_2	1137281.D778_01673	3.949e-16	92.0	COG1345@1|root,COG2356@1|root,COG2866@1|root,COG3386@1|root,COG3897@1|root,COG1345@2|Bacteria,COG2356@2|Bacteria,COG2866@2|Bacteria,COG3386@2|Bacteria,COG3897@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia	976|Bacteroidetes	N	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,LTD
DTH2_k127_6289504_3	1121481.AUAS01000029_gene5305	2.101e-07	64.0	COG3391@1|root,COG4886@1|root,COG3391@2|Bacteria,COG4886@2|Bacteria,4NJXD@976|Bacteroidetes	2|Bacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,DUF285,LRR_4,MucBP
DTH2_k127_6293490_3	1433126.BN938_0236	7.518e-15	74.0	COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,2FMM2@200643|Bacteroidia,22UBP@171550|Rikenellaceae	976|Bacteroidetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DTH2_k127_6293490_1	1121101.HMPREF1532_00539	1.523e-67	234.0	COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,2FN36@200643|Bacteroidia,4AKBS@815|Bacteroidaceae	976|Bacteroidetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DTH2_k127_6293490_2	1279009.ADICEAN_02055	1.297e-48	180.0	COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,47NVP@768503|Cytophagia	976|Bacteroidetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DTH2_k127_6293490_0	391598.FBBAL38_04460	1.343e-126	412.0	COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,1HXYP@117743|Flavobacteriia	976|Bacteroidetes	EF	ribose-phosphate pyrophosphokinase	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
DTH2_k127_6312159_3	1313301.AUGC01000003_gene2106	3.203e-51	185.0	COG0399@1|root,COG0399@2|Bacteria,4NEIU@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_6312159_1	1122176.KB903550_gene4342	3.984e-74	255.0	COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,1IRZ1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH2_k127_6312159_2	1042376.AFPK01000025_gene849	3.125e-63	222.0	COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,1HXN2@117743|Flavobacteriia,4068A@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	F	Guanylate kinase homologues.	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
DTH2_k127_6312159_0	385682.AFSL01000071_gene1421	2.617e-83	286.0	COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,2FPBF@200643|Bacteroidia,3XJ7R@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
DTH2_k127_6312159_4	1313421.JHBV01000005_gene4574	4.404e-31	126.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1ISPK@117747|Sphingobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_6325053_5	1356852.N008_03915	1.614e-51	193.0	COG0463@1|root,COG0463@2|Bacteria,4NKQ4@976|Bacteroidetes,47KJW@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
DTH2_k127_6325053_6	1268237.G114_10590	7.954e-11	71.0	COG1670@1|root,COG1670@2|Bacteria,1RKAB@1224|Proteobacteria,1S5YC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_6325053_3	575590.HMPREF0156_01605	2.59e-61	218.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes	976|Bacteroidetes	G	polysaccharide deacetylase	pgdA_1	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH2_k127_6325053_0	1168034.FH5T_07405	1.565e-312	989.0	COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia	976|Bacteroidetes	P	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
DTH2_k127_6325053_2	36874.HQ34_06605	2.245e-107	352.0	COG0588@1|root,COG0588@2|Bacteria,4NFP5@976|Bacteroidetes,2FP93@200643|Bacteroidia,22WIZ@171551|Porphyromonadaceae	976|Bacteroidetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
DTH2_k127_6325053_4	313606.M23134_06978	2.98e-60	216.0	COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,47QQR@768503|Cytophagia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
DTH2_k127_6325053_1	880073.Calab_2101	2.18e-241	783.0	COG1361@1|root,COG2911@1|root,COG4935@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4935@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_6328448_0	1408473.JHXO01000004_gene131	0.0	1304.0	COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,2FNFZ@200643|Bacteroidia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,ABC_tran
DTH2_k127_6331151_0	927658.AJUM01000034_gene127	1.013e-187	597.0	COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,2FQNC@200643|Bacteroidia,3XJTF@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldJ	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_6331151_1	1168034.FH5T_05700	4.4e-125	414.0	COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,2FN92@200643|Bacteroidia	976|Bacteroidetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_6331151_2	445961.IW15_18460	2.735e-115	381.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1HWX7@117743|Flavobacteriia,3ZQ3H@59732|Chryseobacterium	976|Bacteroidetes	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
DTH2_k127_6331463_0	1408433.JHXV01000020_gene3544	6.584e-250	802.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes,1IKD4@117743|Flavobacteriia,2PA9C@246874|Cryomorphaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_6331463_2	926562.Oweho_2866	1.784e-38	151.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6331463_1	1408433.JHXV01000022_gene3142	1.635e-93	317.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6338042_0	1168289.AJKI01000027_gene1344	5.208e-115	382.0	COG1373@1|root,COG1373@2|Bacteria,4NE3E@976|Bacteroidetes,2FP33@200643|Bacteroidia,3XKNX@558415|Marinilabiliaceae	976|Bacteroidetes	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
DTH2_k127_6338042_3	1305737.JAFX01000001_gene1343	3.419e-11	66.0	COG3620@1|root,COG3620@2|Bacteria,4NQCR@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DTH2_k127_6338042_2	396588.Tgr7_1942	2.297e-11	71.0	2BZ8N@1|root,33ZRX@2|Bacteria,1N1WI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DTH2_k127_6338042_1	945713.IALB_3120	3.999e-13	70.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,HATPase_c,PKD_3,Reg_prop
DTH2_k127_6341364_0	1507.HMPREF0262_03019	1.564e-72	248.0	COG1574@1|root,COG1574@2|Bacteria,1UY5C@1239|Firmicutes,24A2S@186801|Clostridia,36GSF@31979|Clostridiaceae	186801|Clostridia	S	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
DTH2_k127_6341364_2	1507.HMPREF0262_03018	8.309e-39	147.0	2CDKX@1|root,32RXZ@2|Bacteria,1VC7P@1239|Firmicutes,24MMR@186801|Clostridia,36KQ1@31979|Clostridiaceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	DUF4387
DTH2_k127_6341364_1	56110.Oscil6304_1572	1.809e-48	186.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DTH2_k127_6349391_0	742817.HMPREF9449_02421	1.897e-177	569.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,22XFT@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
DTH2_k127_6349391_1	754035.Mesau_03215	1.717e-11	67.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,43KSH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
DTH2_k127_6349391_2	1450525.JATV01000013_gene2878	4.849e-08	63.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2P057@237|Flavobacterium	976|Bacteroidetes	S	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_6372532_2	1120951.AUBG01000009_gene2866	6.121e-11	64.0	COG0864@1|root,COG0864@2|Bacteria,4NV9H@976|Bacteroidetes,1I5II@117743|Flavobacteriia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
DTH2_k127_6372532_0	269798.CHU_0745	1.004e-28	118.0	COG2337@1|root,COG2337@2|Bacteria,4NTCI@976|Bacteroidetes,47RQE@768503|Cytophagia	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	chpA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DTH2_k127_6372532_1	1313421.JHBV01000005_gene4574	1.902e-28	119.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1ISPK@117747|Sphingobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_6372532_3	1191523.MROS_2082	3.618e-10	68.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH2_k127_6386258_1	1121097.JCM15093_1900	1.568e-72	252.0	COG0053@1|root,COG0053@2|Bacteria,4NFBB@976|Bacteroidetes,2G36X@200643|Bacteroidia,4AWAU@815|Bacteroidaceae	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH2_k127_6386258_0	1237149.C900_01647	0.0	1531.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,47NAM@768503|Cytophagia	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
DTH2_k127_6388043_2	880073.Calab_1754	1.471e-17	98.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
DTH2_k127_6388043_1	1121957.ATVL01000008_gene4315	4.674e-21	109.0	COG3291@1|root,COG3291@2|Bacteria,4PB2A@976|Bacteroidetes,47V1S@768503|Cytophagia	976|Bacteroidetes	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6388043_0	1168289.AJKI01000001_gene3628	1.903e-273	850.0	COG1506@1|root,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,2FM6S@200643|Bacteroidia,3XKNF@558415|Marinilabiliaceae	976|Bacteroidetes	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
DTH2_k127_6416687_2	324602.Caur_1152	8.206e-29	117.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3750H@32061|Chloroflexia	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DTH2_k127_6416687_0	926550.CLDAP_18310	9.424e-168	532.0	COG0444@1|root,COG0444@2|Bacteria,2G5ST@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DTH2_k127_6416687_1	926550.CLDAP_18300	3.322e-89	295.0	COG1173@1|root,COG1173@2|Bacteria,2G648@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
DTH2_k127_644024_0	671143.DAMO_0860	2.365e-129	426.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	glnG	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712,ko:K07714	ko02020,map02020	M00497,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_644024_1	880072.Desac_2387	1.486e-65	243.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
DTH2_k127_6440255_2	1341181.FLJC2902T_10470	5.538e-07	63.0	COG1345@1|root,COG2356@1|root,COG2374@1|root,COG3420@1|root,COG1345@2|Bacteria,COG2356@2|Bacteria,COG2374@2|Bacteria,COG3420@2|Bacteria,4NGSK@976|Bacteroidetes,1HXWK@117743|Flavobacteriia,2P0S4@237|Flavobacterium	976|Bacteroidetes	N	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ASH,LTD
DTH2_k127_6440255_0	1121904.ARBP01000026_gene663	1.374e-98	346.0	COG3591@1|root,COG3591@2|Bacteria,4NG2K@976|Bacteroidetes	976|Bacteroidetes	E	Pkd domain containing protein	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin,Trypsin_2
DTH2_k127_6440255_1	242619.PG_0232	1.982e-14	79.0	COG2866@1|root,COG3291@1|root,COG2866@2|Bacteria,COG3291@2|Bacteria,4NGV7@976|Bacteroidetes,2FRH7@200643|Bacteroidia,230R0@171551|Porphyromonadaceae	976|Bacteroidetes	E	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,PKD,Peptidase_M14
DTH2_k127_6447677_0	323259.Mhun_2462	2.4e-54	192.0	COG0057@1|root,arCOG00493@2157|Archaea,2XT16@28890|Euryarchaeota,2N93N@224756|Methanomicrobia	224756|Methanomicrobia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
DTH2_k127_6447677_2	243164.DET0144	8.747e-44	166.0	COG1670@1|root,COG1670@2|Bacteria,2G76C@200795|Chloroflexi,34DHJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH2_k127_6447677_1	1174528.JH992898_gene3633	4.812e-50	186.0	COG0500@1|root,COG2226@2|Bacteria,1G61F@1117|Cyanobacteria,1JJTA@1189|Stigonemataceae	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH2_k127_6447677_3	1173026.Glo7428_2204	1.016e-31	124.0	COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM response regulator receiveR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH2_k127_6458244_1	485918.Cpin_2807	1.837e-92	314.0	COG0265@1|root,COG0265@2|Bacteria,4NGRE@976|Bacteroidetes	976|Bacteroidetes	O	smart pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH2_k127_6458244_2	1111069.TCCBUS3UF1_3470	3.707e-51	190.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DTH2_k127_6458244_4	1239962.C943_01555	4.409e-22	104.0	2DD3M@1|root,2ZGBQ@2|Bacteria,4P80Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6458244_0	1313421.JHBV01000049_gene75	7.176e-200	632.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
DTH2_k127_6458244_3	1453498.LG45_05720	5.37e-33	146.0	2C5U1@1|root,2Z80K@2|Bacteria,4NG4G@976|Bacteroidetes,1HZNR@117743|Flavobacteriia,2NSK5@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
DTH2_k127_6465179_1	742817.HMPREF9449_01692	2.996e-60	211.0	COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia,22XMM@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DTH2_k127_6465179_0	1408473.JHXO01000006_gene1013	2.418e-135	442.0	COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,2FN50@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH2_k127_6465179_2	1313421.JHBV01000031_gene1559	2.64e-07	60.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,1IQ08@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM gliding motility associated	gldN	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6466205_0	1168034.FH5T_05470	8.888e-171	561.0	COG1502@1|root,COG4085@1|root,COG1502@2|Bacteria,COG4085@2|Bacteria,4NVWC@976|Bacteroidetes,2FZM7@200643|Bacteroidia	976|Bacteroidetes	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
DTH2_k127_6466205_1	153721.MYP_3497	7.261e-114	371.0	COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,47JE4@768503|Cytophagia	976|Bacteroidetes	S	PFAM Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_6477364_0	926562.Oweho_2874	1.717e-58	205.0	COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1HX7A@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DTH2_k127_6477364_1	1296415.JACC01000036_gene1185	1.85e-29	134.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY1Z@117743|Flavobacteriia,2YJ2U@290174|Aquimarina	976|Bacteroidetes	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
DTH2_k127_6477364_2	926562.Oweho_0073	3.207e-17	91.0	COG2885@1|root,COG2885@2|Bacteria,4NE8J@976|Bacteroidetes,1HY0A@117743|Flavobacteriia,2PBF0@246874|Cryomorphaceae	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
DTH2_k127_648159_1	118168.MC7420_5093	7.699e-24	106.0	2EP6P@1|root,33GTE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_648159_0	1548151.LS70_05640	1.006e-151	487.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2YMPE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	epimerase dehydratase family	-	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_6481620_5	1444711.CCJF01000005_gene918	2.246e-21	105.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DTH2_k127_6481620_6	1122176.KB903554_gene3790	9.299e-18	84.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_6481620_0	1122176.KB903554_gene3790	3.795e-243	799.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes	976|Bacteroidetes	T	histidine kinase-, DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_6481620_8	1122973.KB904258_gene1692	3.895e-05	53.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,2FSTK@200643|Bacteroidia,22YUQ@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_6481620_7	269797.Mbar_A1989	4.001e-07	63.0	COG1520@1|root,arCOG02482@2157|Archaea,arCOG02556@2157|Archaea,2XUI1@28890|Euryarchaeota,2NBKV@224756|Methanomicrobia	224756|Methanomicrobia	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NosD,PKD,PQQ_2,PQQ_3
DTH2_k127_6481620_4	1185876.BN8_06492	5.117e-36	153.0	COG5492@1|root,COG5492@2|Bacteria,4PPFX@976|Bacteroidetes,47YMG@768503|Cytophagia	976|Bacteroidetes	N	ZU5 domain	-	-	-	-	-	-	-	-	-	-	-	-	ZU5
DTH2_k127_6481620_9	1121028.ARQE01000008_gene2250	0.0001383	51.0	2DNJE@1|root,32XTK@2|Bacteria,1N282@1224|Proteobacteria,2UCVS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6481620_2	1168034.FH5T_09310	1.799e-88	303.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,2FS6N@200643|Bacteroidia	976|Bacteroidetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
DTH2_k127_6481620_1	468059.AUHA01000004_gene2187	4.295e-177	565.0	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,1IPGT@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
DTH2_k127_6481620_3	927658.AJUM01000034_gene303	1.7e-56	204.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,3XJJ7@558415|Marinilabiliaceae	976|Bacteroidetes	J	DALR_2	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DTH2_k127_6485220_3	313606.M23134_04517	1.341e-89	301.0	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,47KE3@768503|Cytophagia	976|Bacteroidetes	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH2_k127_6485220_2	1150600.ADIARSV_1902	2.695e-111	368.0	COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,1INZA@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH2_k127_6485220_4	1121481.AUAS01000007_gene1026	4.982e-65	229.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_6485220_1	1408433.JHXV01000010_gene496	6.474e-233	759.0	COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1I8E9@117743|Flavobacteriia,2PBCC@246874|Cryomorphaceae	976|Bacteroidetes	M	PFAM WD40-like beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH2_k127_6485220_0	1313301.AUGC01000012_gene1384	0.0	1277.0	COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
DTH2_k127_6485220_5	1313301.AUGC01000004_gene2418	0.0001038	51.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes	976|Bacteroidetes	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH2_k127_6490771_0	1137281.D778_01668	3.128e-217	708.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes,1IKH7@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Sortilin-Vps10
DTH2_k127_6505943_1	742725.HMPREF9450_02159	8.758e-29	118.0	COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,2FNXY@200643|Bacteroidia,22UD4@171550|Rikenellaceae	976|Bacteroidetes	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
DTH2_k127_6505943_2	1150600.ADIARSV_0995	8.374e-06	59.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	yhcR	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_4246,iECS88_1305.ECS88_4396,iLF82_1304.LF82_624	5_nucleotid_C,Metallophos
DTH2_k127_6505943_0	215803.DB30_7610	4.84e-103	367.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_6525445_2	760192.Halhy_5351	4.167e-86	308.0	COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6525445_3	335543.Sfum_0146	1.32e-60	219.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42PE4@68525|delta/epsilon subdivisions,2WK83@28221|Deltaproteobacteria,2MR72@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH2_k127_6525445_5	195522.BD01_0961	3.538e-08	63.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y7P0@28890|Euryarchaeota,245AH@183968|Thermococci	183968|Thermococci	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH2_k127_6525445_1	65093.PCC7418_1410	1.337e-101	347.0	COG1035@1|root,COG1035@2|Bacteria,1GBPD@1117|Cyanobacteria	1117|Cyanobacteria	C	Coenzyme F420 hydrogenase dehydrogenase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FrhB_FdhB_C,FrhB_FdhB_N
DTH2_k127_6525445_6	326427.Cagg_0163	1.401e-06	59.0	COG0392@1|root,COG0392@2|Bacteria,2GADT@200795|Chloroflexi,375NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_6525445_0	742766.HMPREF9455_03215	1.147e-114	373.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,2FPN9@200643|Bacteroidia,22XQM@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_6525445_4	1168034.FH5T_09005	4.743e-34	132.0	COG0614@1|root,COG0614@2|Bacteria,4NRAK@976|Bacteroidetes,2G3C1@200643|Bacteroidia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_65391_7	395494.Galf_2891	3.031e-08	56.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,44V8U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH2_k127_65391_5	1131269.AQVV01000008_gene972	9.225e-34	144.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Prenyltrans,SLH,Y_Y_Y,YkuD
DTH2_k127_65391_3	1382306.JNIM01000001_gene1788	1.802e-41	170.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
DTH2_k127_65391_6	1120973.AQXL01000134_gene1561	4.784e-23	112.0	COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,4H9XV@91061|Bacilli,27843@186823|Alicyclobacillaceae	91061|Bacilli	C	Cytochrome b(N-terminal)/b6/petB	qcrB	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
DTH2_k127_65391_4	1499967.BAYZ01000103_gene3749	1.96e-35	145.0	COG1262@1|root,COG1413@1|root,COG1262@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	MA20_14850	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HEAT_2,HEAT_PBS
DTH2_k127_65391_0	1499967.BAYZ01000095_gene4170	2.644e-92	314.0	COG1131@1|root,COG1131@2|Bacteria,2NNKB@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ccmA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
DTH2_k127_65391_2	1499967.BAYZ01000095_gene4169	1.468e-62	225.0	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
DTH2_k127_65391_1	1131269.AQVV01000004_gene599	4.545e-71	260.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DTH2_k127_65391_8	706587.Desti_2984	8.364e-08	62.0	2DN50@1|root,32VJ4@2|Bacteria,1N8HX@1224|Proteobacteria,42VGC@68525|delta/epsilon subdivisions,2WS94@28221|Deltaproteobacteria,2MS7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH2_k127_6620411_0	869213.JCM21142_41869	5.488e-152	485.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DTH2_k127_6620411_3	1313301.AUGC01000003_gene1996	6.34e-115	378.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH2_k127_6620411_4	714943.Mucpa_0217	1.909e-90	302.0	COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_6620411_1	714943.Mucpa_0218	9.051e-144	478.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
DTH2_k127_6620411_5	1408473.JHXO01000004_gene45	4.473e-77	265.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,4NHF0@976|Bacteroidetes,2FUN6@200643|Bacteroidia	976|Bacteroidetes	C	rubredoxin	rubR	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
DTH2_k127_6620411_6	1077285.AGDG01000016_gene634	6.143e-73	252.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,2FQY1@200643|Bacteroidia,4AQ9D@815|Bacteroidaceae	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
DTH2_k127_6620411_2	869213.JCM21142_42013	4.113e-119	396.0	28N6X@1|root,2ZBBQ@2|Bacteria	2|Bacteria	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH2_k127_6620411_7	313598.MED152_03480	2.202e-19	87.0	COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia,3VV5C@52959|Polaribacter	976|Bacteroidetes	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
DTH2_k127_6622438_0	177437.HRM2_41440	2.387e-23	102.0	COG0399@1|root,COG0399@2|Bacteria,1PRVB@1224|Proteobacteria,431RA@68525|delta/epsilon subdivisions,2X518@28221|Deltaproteobacteria,2MP3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
DTH2_k127_6624615_0	700598.Niako_6262	2.649e-151	483.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,1IQG4@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH2_k127_6624615_1	755732.Fluta_0260	2.628e-67	237.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IIV6@117743|Flavobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DTH2_k127_6631588_2	869213.JCM21142_93591	1.982e-49	181.0	COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
DTH2_k127_6631588_1	1514668.JOOA01000002_gene969	1.591e-90	315.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
DTH2_k127_6631588_0	1514668.JOOA01000002_gene970	2.679e-106	361.0	COG0603@1|root,COG0603@2|Bacteria,1V0EU@1239|Firmicutes,24BK5@186801|Clostridia,3WN9C@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6631588_3	1168034.FH5T_21780	2.892e-47	176.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,2FM82@200643|Bacteroidia	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
DTH2_k127_6650949_0	709991.Odosp_0398	0.0	1049.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,2FNQK@200643|Bacteroidia,22X3D@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
DTH2_k127_6650949_6	1408473.JHXO01000006_gene1314	2.94e-35	147.0	COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6650949_5	984262.SGRA_4178	5.087e-63	222.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,1IQE8@117747|Sphingobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_6650949_4	1094466.KQS_10630	1.444e-93	321.0	COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1HXJW@117743|Flavobacteriia,2NSYP@237|Flavobacterium	976|Bacteroidetes	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_6650949_1	714943.Mucpa_1000	2.667e-178	564.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,1INNJ@117747|Sphingobacteriia	976|Bacteroidetes	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DTH2_k127_6650949_3	1408473.JHXO01000006_gene1066	1.139e-112	374.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,2FM2K@200643|Bacteroidia	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_6650949_2	509635.N824_28660	2.34e-119	389.0	COG1541@1|root,COG1541@2|Bacteria,4NFRI@976|Bacteroidetes,1J0QZ@117747|Sphingobacteriia	976|Bacteroidetes	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_6660294_3	1123228.AUIH01000021_gene125	3.214e-10	61.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,1XHC4@135619|Oceanospirillales	135619|Oceanospirillales	G	catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
DTH2_k127_6660294_2	926550.CLDAP_33710	4.663e-23	113.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH2_k127_6660294_0	485918.Cpin_3102	1.968e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_6660294_1	497964.CfE428DRAFT_1804	2.742e-44	177.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH2_k127_6664843_11	679199.HMPREF9332_01270	7.177e-13	75.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_6,CHU_C,CotH,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_cc,LRR_5,PKD
DTH2_k127_6664843_7	926550.CLDAP_02020	1.674e-29	136.0	COG1520@1|root,COG1520@2|Bacteria,2G93W@200795|Chloroflexi	200795|Chloroflexi	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_6664843_2	459349.CLOAM0984	9.996e-220	729.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_6664843_12	504472.Slin_3586	7.925e-06	60.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Collagen_bind,DUF11,SdrD_B
DTH2_k127_6664843_3	459349.CLOAM0985	1.173e-193	652.0	COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_6664843_15	1565314.OA34_08765	0.0002177	44.0	COG0454@1|root,COG0456@2|Bacteria,1N6E5@1224|Proteobacteria,42UYS@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DTH2_k127_6664843_9	746697.Aeqsu_0043	1.938e-19	95.0	COG5661@1|root,COG5661@2|Bacteria,4NW11@976|Bacteroidetes,1I32R@117743|Flavobacteriia	976|Bacteroidetes	O	secreted Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
DTH2_k127_6664843_4	314230.DSM3645_10052	5.731e-152	498.0	COG0457@1|root,COG0457@2|Bacteria,2IXTF@203682|Planctomycetes	203682|Planctomycetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH2_k127_6664843_10	404380.Gbem_1922	6.979e-18	100.0	COG1361@1|root,COG3055@1|root,COG3420@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
DTH2_k127_6664843_0	880073.Calab_1858	5.194e-276	896.0	COG1361@1|root,COG4447@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,TM_helix
DTH2_k127_6664843_8	755732.Fluta_1487	1.398e-20	106.0	COG3291@1|root,COG3291@2|Bacteria,4NNHP@976|Bacteroidetes,1I21K@117743|Flavobacteriia	976|Bacteroidetes	U	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS,fn3
DTH2_k127_6664843_6	459349.CLOAM1622	3.892e-64	239.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM
DTH2_k127_6664843_14	1408433.JHXV01000001_gene669	4.852e-05	58.0	COG4733@1|root,COG4733@2|Bacteria,4PHUU@976|Bacteroidetes,1HZDA@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha integrin	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_6664843_1	880073.Calab_1858	1.826e-273	896.0	COG1361@1|root,COG4447@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,TM_helix
DTH2_k127_6664843_5	459349.CLOAM0891	4.885e-99	353.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
DTH2_k127_6664843_13	1148.1653894	1.063e-05	51.0	COG4581@1|root,COG4581@2|Bacteria,1G1R1@1117|Cyanobacteria,1H4UG@1142|Synechocystis	1117|Cyanobacteria	L	DSHCT	ski2	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,Helicase_C
DTH2_k127_6696365_0	927658.AJUM01000037_gene2087	2.206e-117	381.0	COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,3XIZU@558415|Marinilabiliaceae	976|Bacteroidetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
DTH2_k127_6696365_1	1449126.JQKL01000008_gene230	9.912e-57	203.0	COG0778@1|root,COG0778@2|Bacteria,1V0Y6@1239|Firmicutes,24HMV@186801|Clostridia,269WT@186813|unclassified Clostridiales	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DTH2_k127_6704195_3	1191523.MROS_1756	9.955e-07	63.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6704195_2	313606.M23134_05970	1.348e-18	102.0	COG1520@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG4447@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4447@2|Bacteria,4PME7@976|Bacteroidetes,47Y2P@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6704195_1	1111069.TCCBUS3UF1_17270	2.952e-37	163.0	COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
DTH2_k127_6704195_0	1237149.C900_05913	6.395e-67	239.0	COG4677@1|root,COG4704@1|root,COG5184@1|root,COG5492@1|root,COG4677@2|Bacteria,COG4704@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PN9Q@976|Bacteroidetes,47Y9H@768503|Cytophagia	976|Bacteroidetes	DZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
DTH2_k127_6709028_2	694427.Palpr_1150	4.994e-20	92.0	COG0332@1|root,COG0332@2|Bacteria,4NFZK@976|Bacteroidetes,2FQ8G@200643|Bacteroidia,22XGN@171551|Porphyromonadaceae	976|Bacteroidetes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH2_k127_6709028_4	123214.PERMA_0798	1.673e-11	73.0	COG3063@1|root,COG3087@1|root,COG3063@2|Bacteria,COG3087@2|Bacteria,2G4AU@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_2,TPR_6,TPR_8
DTH2_k127_6709028_1	760192.Halhy_2468	3.102e-43	175.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
DTH2_k127_6709028_0	153721.MYP_1755	1.958e-61	221.0	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,47PRN@768503|Cytophagia	976|Bacteroidetes	I	PFAM alpha beta hydrolase fold	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH2_k127_6709028_3	1121904.ARBP01000009_gene4232	4.877e-16	81.0	2EQZ1@1|root,33IIQ@2|Bacteria,4NXHA@976|Bacteroidetes,47T71@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6714217_0	945713.IALB_0147	4.603e-89	329.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
DTH2_k127_6740646_7	1499967.BAYZ01000147_gene739	1.497e-39	151.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	MA20_27600	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	-
DTH2_k127_6740646_6	96561.Dole_3189	1.126e-40	157.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	ko:K13613	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	Methyltransf_21
DTH2_k127_6740646_2	1191523.MROS_0358	2.305e-76	263.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_6740646_3	1191523.MROS_0359	8.334e-76	268.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,His_kinase
DTH2_k127_6740646_5	927658.AJUM01000042_gene1684	4.89e-48	181.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,2FMXH@200643|Bacteroidia,3XKC3@558415|Marinilabiliaceae	976|Bacteroidetes	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
DTH2_k127_6740646_4	1095752.HMPREF9969_0118	2.239e-61	225.0	COG0464@1|root,COG0464@2|Bacteria,4PM8W@976|Bacteroidetes,2FT0M@200643|Bacteroidia	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,Pkinase
DTH2_k127_6740646_0	468059.AUHA01000005_gene2617	5.586e-126	418.0	COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,1IRPR@117747|Sphingobacteriia	976|Bacteroidetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
DTH2_k127_6740646_8	743722.Sph21_1455	7.291e-17	82.0	COG1722@1|root,COG1722@2|Bacteria,4PA4P@976|Bacteroidetes,1IU2S@117747|Sphingobacteriia	976|Bacteroidetes	L	Exonuclease VII small subunit	-	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
DTH2_k127_6740646_9	1121896.JMLU01000001_gene903	8.467e-05	50.0	2AK3I@1|root,31ATB@2|Bacteria,4PIKV@976|Bacteroidetes,1IND7@117743|Flavobacteriia,2NZ57@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6740646_1	1094466.KQS_11045	3.93e-88	311.0	2ABJQ@1|root,31114@2|Bacteria,4PFPZ@976|Bacteroidetes,1IDGB@117743|Flavobacteriia,2NYC4@237|Flavobacterium	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH2_k127_6764041_4	1379698.RBG1_1C00001G0583	8.774e-06	49.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
DTH2_k127_6764041_1	694427.Palpr_1670	6.188e-66	231.0	COG2836@1|root,COG2836@2|Bacteria,4NIC3@976|Bacteroidetes,2FZDZ@200643|Bacteroidia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
DTH2_k127_6764041_0	319225.Plut_1862	1.737e-87	304.0	COG0438@1|root,COG0438@2|Bacteria,1FF84@1090|Chlorobi	1090|Chlorobi	H	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6764041_2	1121957.ATVL01000007_gene2106	6.678e-33	146.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LGT
DTH2_k127_6764041_3	272562.CA_C2010	1.183e-06	53.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,36F9T@31979|Clostridiaceae	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH2_k127_676508_2	926562.Oweho_0093	6.704e-78	269.0	COG0577@1|root,COG0577@2|Bacteria,4PPA9@976|Bacteroidetes,1IKGZ@117743|Flavobacteriia,2PC4C@246874|Cryomorphaceae	2|Bacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_676508_0	742726.HMPREF9448_00547	1.352e-215	680.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,22WKZ@171551|Porphyromonadaceae	976|Bacteroidetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DTH2_k127_676508_1	755732.Fluta_1895	5.959e-167	529.0	COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,1HXDD@117743|Flavobacteriia,2PACA@246874|Cryomorphaceae	976|Bacteroidetes	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DTH2_k127_676508_3	385682.AFSL01000023_gene2168	1.799e-24	108.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia,3XIT1@558415|Marinilabiliaceae	976|Bacteroidetes	M	rod shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DTH2_k127_6768846_2	595494.Tola_1404	4.245e-108	354.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH2_k127_6768846_4	1120951.AUBG01000004_gene2544	9.342e-51	184.0	2APQJ@1|root,31EUD@2|Bacteria,4NNU5@976|Bacteroidetes,1I2CM@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6768846_0	999419.HMPREF1077_01004	2.757e-204	648.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,2FPXP@200643|Bacteroidia,22ZQH@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DTH2_k127_6768846_1	1356852.N008_03065	7.863e-165	530.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
DTH2_k127_6768846_6	886377.Murru_1618	8.712e-43	161.0	COG4319@1|root,COG4319@2|Bacteria,4NNSF@976|Bacteroidetes,1I234@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
DTH2_k127_6768846_3	760192.Halhy_3805	1.047e-67	249.0	COG1807@1|root,COG1807@2|Bacteria,4NJ43@976|Bacteroidetes	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_6768846_5	694427.Palpr_0010	9.548e-45	169.0	COG1943@1|root,COG1943@2|Bacteria,4NQHI@976|Bacteroidetes,2G3BM@200643|Bacteroidia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH2_k127_6768846_7	1122176.KB903541_gene190	4.003e-38	151.0	COG3258@1|root,COG3258@2|Bacteria,4PMKG@976|Bacteroidetes	976|Bacteroidetes	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
DTH2_k127_6768846_8	742766.HMPREF9455_03198	1.449e-23	102.0	COG2388@1|root,COG2388@2|Bacteria,4NST0@976|Bacteroidetes,2FV3H@200643|Bacteroidia,22YR3@171551|Porphyromonadaceae	976|Bacteroidetes	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
DTH2_k127_6770667_2	1313301.AUGC01000004_gene2301	1.02e-16	81.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes	976|Bacteroidetes	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
DTH2_k127_6770667_0	1296415.JACC01000023_gene4280	5.971e-188	591.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia,2YH70@290174|Aquimarina	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
DTH2_k127_6770667_1	1461577.CCMH01000014_gene602	1.975e-186	590.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
DTH2_k127_6782831_2	468059.AUHA01000006_gene3062	4.536e-47	172.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DTH2_k127_6782831_4	1250005.PHEL85_0250	3.719e-07	60.0	COG4886@1|root,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1HYVY@117743|Flavobacteriia,3VX3K@52959|Polaribacter	976|Bacteroidetes	I	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH,LRR_4,TSP_3
DTH2_k127_6782831_3	694427.Palpr_2226	1.388e-41	162.0	COG3656@1|root,COG3656@2|Bacteria,4NHDQ@976|Bacteroidetes,2FTSH@200643|Bacteroidia,22Y91@171551|Porphyromonadaceae	976|Bacteroidetes	S	Fibronectin type 3 domain	-	-	-	ko:K21571	-	-	-	-	ko00000	-	-	-	-
DTH2_k127_6782831_5	906888.JCM19314_2300	2.125e-06	55.0	COG1396@1|root,COG1396@2|Bacteria,4NPYD@976|Bacteroidetes,1IJ1V@117743|Flavobacteriia,3HKMM@363408|Nonlabens	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DTH2_k127_6782831_1	153721.MYP_2232	1.638e-76	267.0	COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,47KB5@768503|Cytophagia	976|Bacteroidetes	E	Isopropylmalate homocitrate citramalate synthase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
DTH2_k127_6782831_0	760568.Desku_0503	6.468e-161	512.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,24AUV@186801|Clostridia,264RD@186807|Peptococcaceae	186801|Clostridia	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
DTH2_k127_6787819_0	1408473.JHXO01000004_gene171	7.68e-192	615.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,2FW8B@200643|Bacteroidia	976|Bacteroidetes	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
DTH2_k127_6787819_1	1235803.C825_04099	7.235e-116	379.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,2FNRH@200643|Bacteroidia,22VZU@171551|Porphyromonadaceae	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DTH2_k127_6828870_3	1265503.KB905160_gene2951	7.763e-18	95.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,1RN4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	gt2M	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_6828870_1	342949.PNA2_1692	1.446e-68	250.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,243ZB@183968|Thermococci	183968|Thermococci	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH2_k127_6828870_2	266117.Rxyl_0513	1.79e-58	212.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4CQ62@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_6828870_4	269797.Mbar_A0608	1.975e-10	72.0	COG0535@1|root,arCOG00938@2157|Archaea,2XZ9M@28890|Euryarchaeota,2NANF@224756|Methanomicrobia	224756|Methanomicrobia	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
DTH2_k127_6828870_0	755732.Fluta_3544	4.312e-113	371.0	COG4122@1|root,COG4122@2|Bacteria,4NJV1@976|Bacteroidetes,1HYRV@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
DTH2_k127_6832092_0	929556.Solca_1315	1.423e-168	535.0	COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_6832092_1	264462.Bd2133	0.0003183	51.0	COG0729@1|root,COG3210@1|root,COG0729@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K07277,ko:K07278,ko:K21449	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4,1.B.40.2	-	-	Bac_surface_Ag,Beta_helix,PATR,POTRA,Peptidase_S74
DTH2_k127_6832241_0	1150600.ADIARSV_3554	2.707e-131	432.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1INUT@117747|Sphingobacteriia	976|Bacteroidetes	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
DTH2_k127_6832241_3	385682.AFSL01000053_gene497	1.655e-26	111.0	COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,2FV7C@200643|Bacteroidia,3XKCW@558415|Marinilabiliaceae	976|Bacteroidetes	S	RNA recognition motif	ykfA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH2_k127_6832241_1	1123008.KB905696_gene2965	3.467e-61	214.0	COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,2FSMJ@200643|Bacteroidia,22XW1@171551|Porphyromonadaceae	976|Bacteroidetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
DTH2_k127_6832241_2	908937.Prede_0964	5.737e-51	190.0	COG0235@1|root,COG0235@2|Bacteria,4NIQK@976|Bacteroidetes,2FN5U@200643|Bacteroidia	976|Bacteroidetes	G	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	rhaD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
DTH2_k127_6832241_4	1550091.JROE01000004_gene1523	2.511e-22	99.0	COG1409@1|root,COG1409@2|Bacteria,4NMNF@976|Bacteroidetes,1J1A3@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH2_k127_6832418_1	456442.Mboo_1908	9.464e-52	187.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota,2NB1F@224756|Methanomicrobia	224756|Methanomicrobia	S	Roadblock LC7	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
DTH2_k127_6832418_2	593750.Metfor_1067	8.95e-25	112.0	arCOG09603@1|root,arCOG09603@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6832418_3	456442.Mboo_1910	1.91e-07	59.0	arCOG03412@1|root,arCOG03412@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
DTH2_k127_6832418_0	593750.Metfor_1065	2.893e-111	364.0	COG0455@1|root,arCOG00589@2157|Archaea,2XT20@28890|Euryarchaeota,2N9KH@224756|Methanomicrobia	224756|Methanomicrobia	D	TIGRFAM cell division ATPase MinD	-	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA
DTH2_k127_6833332_5	679926.Mpet_2531	7.608e-33	130.0	arCOG06820@1|root,arCOG06820@2157|Archaea,2XVYD@28890|Euryarchaeota,2N917@224756|Methanomicrobia	224756|Methanomicrobia	S	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	YoaP
DTH2_k127_6833332_2	1121895.Q765_13305	4.651e-55	197.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,1I2JH@117743|Flavobacteriia,2NWW6@237|Flavobacterium	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
DTH2_k127_6833332_1	1121895.Q765_13310	4.715e-58	205.0	COG5642@1|root,COG5642@2|Bacteria,4NN76@976|Bacteroidetes,1I1NV@117743|Flavobacteriia,2NX3Z@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
DTH2_k127_6833332_4	269798.CHU_1426	2.858e-43	161.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,47R0R@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DTH2_k127_6833332_6	1121895.Q765_02840	2e-09	63.0	COG4886@1|root,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I4F0@117743|Flavobacteriia,2P058@237|Flavobacterium	976|Bacteroidetes	S	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6833332_0	153721.MYP_1468	2.218e-80	274.0	2C73B@1|root,330Z7@2|Bacteria,4NMGE@976|Bacteroidetes,47QBM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6833332_3	1121373.KB903634_gene708	2.691e-54	202.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,47K4K@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_6834211_0	1408473.JHXO01000005_gene1572	3.975e-143	466.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FQDG@200643|Bacteroidia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_684727_0	1121007.AUML01000045_gene3617	6.918e-258	803.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia,2YIX7@290174|Aquimarina	976|Bacteroidetes	O	C-terminal, D2-small domain, of ClpB protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DTH2_k127_684727_1	1313301.AUGC01000001_gene1496	5.104e-208	661.0	COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes	976|Bacteroidetes	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_6859780_4	1121129.KB903374_gene558	0.0001086	45.0	COG4690@1|root,COG4690@2|Bacteria,4NE03@976|Bacteroidetes,2FPSX@200643|Bacteroidia,22WBK@171551|Porphyromonadaceae	976|Bacteroidetes	M	Dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
DTH2_k127_6859780_1	313612.L8106_04386	4.438e-35	137.0	2AFHA@1|root,315HT@2|Bacteria,1G5WD@1117|Cyanobacteria,1HBUI@1150|Oscillatoriales	1117|Cyanobacteria	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_6859780_0	768710.DesyoDRAFT_2226	6.248e-125	411.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,2606H@186807|Peptococcaceae	186801|Clostridia	E	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_6859780_2	1349822.NSB1T_01575	5.667e-34	142.0	COG4372@1|root,COG4372@2|Bacteria,4PKE4@976|Bacteroidetes,2FPKQ@200643|Bacteroidia,22W9H@171551|Porphyromonadaceae	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6859780_3	1408433.JHXV01000029_gene3101	5.745e-20	99.0	COG4083@1|root,COG4083@2|Bacteria,4P9XV@976|Bacteroidetes,1IM56@117743|Flavobacteriia,2PC15@246874|Cryomorphaceae	976|Bacteroidetes	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
DTH2_k127_6877697_1	1239962.C943_00988	4.742e-184	583.0	COG2704@1|root,COG2704@2|Bacteria,4NGDF@976|Bacteroidetes,47T5H@768503|Cytophagia	976|Bacteroidetes	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
DTH2_k127_6877697_8	1396141.BATP01000001_gene5335	3.869e-21	96.0	COG4566@1|root,COG4566@2|Bacteria,46VMR@74201|Verrucomicrobia,2IW32@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH2_k127_6877697_6	1040989.AWZU01000002_gene5221	3.527e-48	179.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,3JQPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_6877697_3	113395.AXAI01000038_gene112	1.297e-77	283.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JT51@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA
DTH2_k127_6877697_9	929703.KE386491_gene4128	2.874e-15	89.0	COG5295@1|root,COG5295@2|Bacteria,4PHWW@976|Bacteroidetes,47ST5@768503|Cytophagia	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6877697_5	1408433.JHXV01000002_gene445	1.51e-51	196.0	COG4782@1|root,COG4782@2|Bacteria,4NS8M@976|Bacteroidetes	976|Bacteroidetes	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
DTH2_k127_6877697_10	458817.Shal_2446	1.022e-14	83.0	COG1226@1|root,32Y28@2|Bacteria,1N59I@1224|Proteobacteria,1T0M9@1236|Gammaproteobacteria,2QANF@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
DTH2_k127_6877697_2	886379.AEWI01000005_gene913	2.923e-154	497.0	COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,2FNG4@200643|Bacteroidia,3XJ51@558415|Marinilabiliaceae	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_6877697_0	880073.Calab_1598	0.0	1124.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
DTH2_k127_6877697_11	1121957.ATVL01000009_gene1082	2.228e-10	75.0	COG1506@1|root,COG2273@1|root,COG3209@1|root,COG4447@1|root,COG1506@2|Bacteria,COG2273@2|Bacteria,COG3209@2|Bacteria,COG4447@2|Bacteria,4PKQ3@976|Bacteroidetes,47N9J@768503|Cytophagia	976|Bacteroidetes	E	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Peptidase_S9
DTH2_k127_6877697_7	926564.KI911691_gene1206	2.124e-30	141.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2HQIW@201174|Actinobacteria,4F5H7@85017|Promicromonosporaceae	2|Bacteria	O	Subtilase family	nanM	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005623,GO:0016853,GO:0016854,GO:0016857,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	5.1.3.24	ko:K13276,ko:K17948	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Kelch_1,Kelch_4,Kelch_6,Malectin,PKD,Peptidase_M6,Peptidase_S8
DTH2_k127_6877697_4	1120951.AUBG01000011_gene2419	4.519e-72	276.0	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,MAM,PepSY,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,fn3
DTH2_k127_6878062_3	1121129.KB903359_gene1550	3.17e-36	141.0	COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia,22WND@171551|Porphyromonadaceae	976|Bacteroidetes	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DTH2_k127_6878062_4	1168034.FH5T_11555	1.552e-31	129.0	2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,2FPJA@200643|Bacteroidia	976|Bacteroidetes	S	rod shape-determining protein MreD	mreD	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6878062_1	1408473.JHXO01000004_gene208	1.998e-86	299.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia	976|Bacteroidetes	CO	AhpC Tsa family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
DTH2_k127_6878062_0	929556.Solca_3245	6.099e-171	548.0	COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,1INSU@117747|Sphingobacteriia	976|Bacteroidetes	C	iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	Fer4_8,LUD_dom
DTH2_k127_6878062_2	1338011.BD94_4069	3.101e-55	196.0	COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,1I24B@117743|Flavobacteriia,34R6Q@308865|Elizabethkingia	976|Bacteroidetes	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
DTH2_k127_687962_1	1408473.JHXO01000004_gene116	3.173e-55	203.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,2G2Z3@200643|Bacteroidia	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
DTH2_k127_687962_0	1380384.JADN01000003_gene426	3.645e-84	286.0	COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1HYBQ@117743|Flavobacteriia	976|Bacteroidetes	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DTH2_k127_6879779_3	1121373.KB903632_gene480	2.074e-05	47.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
DTH2_k127_6879779_2	1450525.JATV01000002_gene2103	3.625e-27	116.0	2CG1Y@1|root,333IH@2|Bacteria,4NVMK@976|Bacteroidetes,1I9TA@117743|Flavobacteriia,2NWI3@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH2_k127_6879779_0	313606.M23134_03354	1.977e-106	359.0	COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47M71@768503|Cytophagia	976|Bacteroidetes	T	Signal transduction histidine kinase	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_6879779_1	1122176.KB903543_gene611	8.777e-75	258.0	COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,1IXKQ@117747|Sphingobacteriia	976|Bacteroidetes	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_6887541_4	1123229.AUBC01000024_gene4566	6.361e-06	48.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,3JRQT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
DTH2_k127_6887541_2	368407.Memar_1819	1.119e-27	113.0	COG1476@1|root,arCOG01864@2157|Archaea,2XZS8@28890|Euryarchaeota,2NB5P@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
DTH2_k127_6887541_0	456442.Mboo_1105	2.179e-225	705.0	COG1850@1|root,arCOG04443@2157|Archaea,2XVBP@28890|Euryarchaeota,2N9IP@224756|Methanomicrobia	224756|Methanomicrobia	G	Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase	rbcL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0902	RuBisCO_large,RuBisCO_large_N
DTH2_k127_6887541_1	456442.Mboo_1628	1.053e-50	185.0	arCOG05293@1|root,arCOG05293@2157|Archaea	2157|Archaea	G	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
DTH2_k127_6887541_3	593750.Metfor_2573	6.837e-15	76.0	arCOG09584@1|root,arCOG09584@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6891738_5	1313421.JHBV01000013_gene3740	5.793e-28	117.0	COG1028@1|root,COG1028@2|Bacteria	1313421.JHBV01000013_gene3740|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6891738_4	443254.Marpi_1490	6.371e-39	154.0	COG1449@1|root,COG4945@1|root,COG1449@2|Bacteria,COG4945@2|Bacteria,2GC51@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Glucodextran_C,Glyco_hydro_57
DTH2_k127_6891738_0	1121904.ARBP01000001_gene5939	6.243e-71	248.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47JAF@768503|Cytophagia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_6891738_2	1131812.JQMS01000001_gene2616	1.992e-52	198.0	COG2972@1|root,COG2972@2|Bacteria,4NMDQ@976|Bacteroidetes,1I1GC@117743|Flavobacteriia,2NU5R@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
DTH2_k127_6891738_1	452637.Oter_2137	2.983e-64	231.0	COG2006@1|root,COG2006@2|Bacteria,46U2P@74201|Verrucomicrobia,3K77Y@414999|Opitutae	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH2_k127_6891738_3	1408433.JHXV01000022_gene3135	6.053e-50	205.0	COG3291@1|root,COG3291@2|Bacteria,4NRDH@976|Bacteroidetes,1IIK5@117743|Flavobacteriia,2PBFR@246874|Cryomorphaceae	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_6891738_6	1122179.KB890414_gene1916	2.697e-07	65.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_690215_1	1501391.LG35_08285	1.206e-45	166.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,2FN1R@200643|Bacteroidia,22U0K@171550|Rikenellaceae	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH2_k127_690215_0	1408473.JHXO01000011_gene3040	4.193e-109	362.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,2FME3@200643|Bacteroidia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_690215_2	385682.AFSL01000002_gene1872	3.361e-31	124.0	COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,2FTI6@200643|Bacteroidia,3XK3K@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, mercury resistance	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
DTH2_k127_6923138_7	1168034.FH5T_06145	5.68e-60	216.0	COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,2FMPK@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
DTH2_k127_6923138_5	1408473.JHXO01000001_gene2475	8.975e-70	252.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,2FN33@200643|Bacteroidia	976|Bacteroidetes	I	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
DTH2_k127_6923138_6	1168289.AJKI01000011_gene360	1.146e-69	253.0	COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,3XJQ1@558415|Marinilabiliaceae	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH2_k127_6923138_9	926562.Oweho_0083	1.451e-23	108.0	COG3117@1|root,COG3117@2|Bacteria,4P9FE@976|Bacteroidetes,1IDW5@117743|Flavobacteriia,2PB77@246874|Cryomorphaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
DTH2_k127_6923138_4	1120966.AUBU01000006_gene3318	2.075e-116	388.0	COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,47KQX@768503|Cytophagia	976|Bacteroidetes	S	CBS domain	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
DTH2_k127_6923138_2	385682.AFSL01000082_gene1182	4.37e-125	427.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,3XJMY@558415|Marinilabiliaceae	976|Bacteroidetes	O	SurA N-terminal domain	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
DTH2_k127_6923138_1	929556.Solca_0351	2.259e-144	469.0	COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,1INPB@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
DTH2_k127_6923138_0	1408473.JHXO01000011_gene2965	1.702e-193	621.0	COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,2FM4X@200643|Bacteroidia	976|Bacteroidetes	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
DTH2_k127_6923138_10	1408433.JHXV01000007_gene2952	1.138e-13	78.0	2A5B1@1|root,30U0G@2|Bacteria,4PHGE@976|Bacteroidetes,1IC33@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_6923138_3	886377.Murru_0989	5.371e-119	391.0	COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia	976|Bacteroidetes	IQ	acyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
DTH2_k127_6923138_8	1408473.JHXO01000013_gene628	2.842e-42	159.0	COG1051@1|root,COG1051@2|Bacteria,4NSQ1@976|Bacteroidetes,2FU0I@200643|Bacteroidia	976|Bacteroidetes	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DTH2_k127_6933512_0	1408473.JHXO01000013_gene523	4.048e-195	615.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,2FNXA@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_6933555_2	880073.Calab_2100	1.841e-09	68.0	COG2957@1|root,COG2957@2|Bacteria	2|Bacteria	E	agmatine deiminase activity	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
DTH2_k127_6933555_0	649349.Lbys_0312	1.789e-44	169.0	COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,47QH7@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	yihX	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH2_k127_6933555_1	1168034.FH5T_10085	2.806e-28	117.0	2CCSR@1|root,32RSC@2|Bacteria,4NT8X@976|Bacteroidetes	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_6933555_3	994573.T472_0216265	0.0004566	43.0	COG0697@1|root,COG0697@2|Bacteria,1V009@1239|Firmicutes,24DF1@186801|Clostridia,36GKS@31979|Clostridiaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_693533_1	709991.Odosp_0309	1.056e-64	231.0	COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia,22XC3@171551|Porphyromonadaceae	976|Bacteroidetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH2_k127_693533_5	880073.Calab_3627	6.816e-13	82.0	COG2374@1|root,COG2911@1|root,COG3386@1|root,COG2374@2|Bacteria,COG2911@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	gnl	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	1.15.1.1,2.7.11.1,3.1.1.17,3.1.1.2,3.1.3.8,3.1.8.1,3.2.1.4,4.3.3.2	ko:K01045,ko:K01053,ko:K01083,ko:K01179,ko:K01757,ko:K02057,ko:K04565,ko:K08884,ko:K13735	ko00030,ko00053,ko00500,ko00562,ko00901,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko04146,ko04213,ko05014,ko05016,ko05020,ko05100,map00030,map00053,map00500,map00562,map00901,map00930,map01100,map01110,map01120,map01130,map01200,map01220,map04146,map04213,map05014,map05016,map05020,map05100	M00129,M00221	R01519,R02933,R03371,R03738,R03751,R06200,R11307,R11308	RC00078,RC00537,RC00983,RC01072,RC01568	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko04147	3.A.1.2	GH5,GH9	-	SGL,Str_synth
DTH2_k127_693533_7	1121930.AQXG01000004_gene2843	0.0005747	53.0	COG0737@1|root,COG2356@1|root,COG0737@2|Bacteria,COG2356@2|Bacteria,4PPNB@976|Bacteroidetes,1IY1S@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	LTD
DTH2_k127_693533_3	309801.trd_A0679	2.99e-36	158.0	COG3420@1|root,COG3420@2|Bacteria,2GBD6@200795|Chloroflexi,27YVB@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH2_k127_693533_6	1122226.AUHX01000016_gene60	0.000142	55.0	COG3291@1|root,COG3291@2|Bacteria,4NJCR@976|Bacteroidetes,1HZA7@117743|Flavobacteriia	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SdrD_B
DTH2_k127_693533_4	1385513.N780_16950	8.204e-17	83.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,4HA3H@91061|Bacilli,2Y8Z0@289201|Pontibacillus	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
DTH2_k127_693533_0	1168034.FH5T_17590	2.02e-170	554.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,2G2QE@200643|Bacteroidia	976|Bacteroidetes	O	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
DTH2_k127_693533_2	468059.AUHA01000002_gene1253	1.678e-46	171.0	COG2246@1|root,COG2246@2|Bacteria,4NTZF@976|Bacteroidetes,1IU98@117747|Sphingobacteriia	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
DTH2_k127_6943952_0	1121904.ARBP01000003_gene6417	5.144e-199	648.0	COG4886@1|root,COG4886@2|Bacteria,4NHJ3@976|Bacteroidetes,47NN3@768503|Cytophagia	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_6943952_1	1047013.AQSP01000061_gene1215	6.084e-81	277.0	COG1028@1|root,COG1028@2|Bacteria,2NRAR@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH2_k127_6943952_2	96561.Dole_0290	1.188e-79	270.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,42Q82@68525|delta/epsilon subdivisions,2WMBU@28221|Deltaproteobacteria,2MI8W@213118|Desulfobacterales	28221|Deltaproteobacteria	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
DTH2_k127_6947390_7	929556.Solca_4383	1.863e-14	74.0	COG5512@1|root,COG5512@2|Bacteria,4NSDR@976|Bacteroidetes,1ITAK@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
DTH2_k127_6947390_3	509635.N824_25380	2.064e-127	421.0	COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,1INV5@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
DTH2_k127_6947390_2	1349822.NSB1T_02690	4.476e-156	512.0	COG0615@1|root,COG2605@1|root,COG0615@2|Bacteria,COG2605@2|Bacteria,4NGSD@976|Bacteroidetes,2FQ1X@200643|Bacteroidia,22WKK@171551|Porphyromonadaceae	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GHMP_kinases_C
DTH2_k127_6947390_6	1047013.AQSP01000133_gene2140	4.132e-32	144.0	COG3254@1|root,COG3254@2|Bacteria,2NRFN@2323|unclassified Bacteria	2|Bacteria	S	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
DTH2_k127_6947390_5	929556.Solca_0543	1.064e-83	282.0	COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	fahA	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DTH2_k127_6947390_4	525373.HMPREF0766_13755	5.307e-99	329.0	COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,1IPA8@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
DTH2_k127_6947390_1	760192.Halhy_3578	1.606e-159	514.0	COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH2_k127_6947390_0	1168034.FH5T_21745	3.973e-215	687.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia	976|Bacteroidetes	S	Glycosyltransferase, group 2 family protein	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_6947390_8	643867.Ftrac_0364	6.53e-07	53.0	COG0644@1|root,COG0644@2|Bacteria,4NKR8@976|Bacteroidetes,47SE4@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM geranylgeranyl reductase family	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3,Trp_halogenase
DTH2_k127_6974718_3	760568.Desku_1343	1.999e-05	53.0	COG3039@1|root,COG3039@2|Bacteria,1TQF8@1239|Firmicutes,24AUQ@186801|Clostridia,265DS@186807|Peptococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6
DTH2_k127_6974718_0	1218173.BALCAV_0216725	4.423e-92	313.0	COG0582@1|root,COG0582@2|Bacteria,1V78A@1239|Firmicutes,4ITPQ@91061|Bacilli	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DTH2_k127_6974718_2	1218173.BALCAV_0216725	4.538e-20	91.0	COG0582@1|root,COG0582@2|Bacteria,1V78A@1239|Firmicutes,4ITPQ@91061|Bacilli	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DTH2_k127_6974718_1	1218173.BALCAV_0216720	1.172e-48	178.0	COG0582@1|root,COG0582@2|Bacteria,1V2MU@1239|Firmicutes,4ITPP@91061|Bacilli,1ZGW5@1386|Bacillus	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DTH2_k127_6977197_4	762903.Pedsa_0133	2.08e-104	353.0	COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,1IPWG@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DTH2_k127_6977197_3	762903.Pedsa_0132	2.692e-169	543.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1INPJ@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH2_k127_6977197_2	929556.Solca_2741	4.926e-183	580.0	COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1IQU9@117747|Sphingobacteriia	976|Bacteroidetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
DTH2_k127_6977197_0	1358423.N180_11935	4.547e-193	613.0	COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH2_k127_6977197_1	929556.Solca_2743	1.075e-187	609.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,4NERV@976|Bacteroidetes,1IQ79@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell division protein FtsI penicillin-binding protein 2	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH2_k127_698770_3	391625.PPSIR1_16360	6.947e-81	280.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DTH2_k127_698770_2	1313421.JHBV01000029_gene2007	2.558e-86	292.0	2DBF0@1|root,2Z8VT@2|Bacteria,4NECW@976|Bacteroidetes	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
DTH2_k127_698770_1	203275.BFO_1627	3.399e-97	326.0	COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,2FNQ7@200643|Bacteroidia,22W19@171551|Porphyromonadaceae	976|Bacteroidetes	P	Transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
DTH2_k127_698770_0	1408473.JHXO01000007_gene788	1.177e-152	494.0	COG2176@1|root,COG2176@2|Bacteria,4PM8C@976|Bacteroidetes,2FW8F@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG type nucleases (URI domain)	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
DTH2_k127_698770_4	927658.AJUM01000042_gene1718	2.796e-64	225.0	COG1396@1|root,COG1396@2|Bacteria,4PP35@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DTH2_k127_6991480_4	999419.HMPREF1077_01811	1.047e-25	107.0	COG0826@1|root,COG0826@2|Bacteria,4NERN@976|Bacteroidetes,2FN1E@200643|Bacteroidia,22VVZ@171551|Porphyromonadaceae	976|Bacteroidetes	O	collagenase	prtC	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
DTH2_k127_6991480_2	1123288.SOV_5c02010	1.054e-123	412.0	COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4H2EQ@909932|Negativicutes	909932|Negativicutes	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
DTH2_k127_6991480_3	1249975.JQLP01000005_gene1422	8.39e-91	304.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1HYTE@117743|Flavobacteriia	976|Bacteroidetes	P	COG0569 K transport systems NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DTH2_k127_6991480_1	1249975.JQLP01000005_gene1423	2.465e-194	622.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1HY9Z@117743|Flavobacteriia	976|Bacteroidetes	P	potassium uptake protein, TrkH family	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DTH2_k127_6991480_0	1313301.AUGC01000016_gene840	1.664e-244	761.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes	976|Bacteroidetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DTH2_k127_7051141_0	1191523.MROS_1186	1.193e-214	676.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
DTH2_k127_7051141_2	1168034.FH5T_16955	2.18e-53	194.0	COG4117@1|root,COG4117@2|Bacteria	2|Bacteria	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	ydhU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620,ko:K08354	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10149	RC02823	ko00000,ko00001,ko02000	5.A.3.5	-	-	Cytochrome_C7,Ni_hydr_CYTB
DTH2_k127_7051141_1	1168034.FH5T_16960	5.919e-81	280.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
DTH2_k127_7051141_3	1168034.FH5T_16965	1.187e-50	190.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7052013_0	661478.OP10G_1753	8.547e-35	150.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.73	ko:K01216	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_16
DTH2_k127_7052013_2	1470591.BW41_02499	2.306e-10	66.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K4Q4@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
DTH2_k127_7052013_3	694429.Pyrfu_1713	0.0001316	52.0	COG1637@1|root,arCOG01304@2157|Archaea,2XQ7Z@28889|Crenarchaeota	28889|Crenarchaeota	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
DTH2_k127_7052882_2	102125.Xen7305DRAFT_00041280	2.032e-31	125.0	COG2355@1|root,COG2355@2|Bacteria,1G8RV@1117|Cyanobacteria,3VKZC@52604|Pleurocapsales	1117|Cyanobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
DTH2_k127_7052882_0	1408473.JHXO01000010_gene3587	3.8e-143	456.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,2FM46@200643|Bacteroidia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DTH2_k127_7052882_1	1168034.FH5T_04800	6.127e-58	206.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,2FT42@200643|Bacteroidia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
DTH2_k127_7052882_3	755732.Fluta_0947	3.629e-11	72.0	2A7NQ@1|root,30WKT@2|Bacteria,4PA0D@976|Bacteroidetes,1IF21@117743|Flavobacteriia,2PBZY@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7054021_1	1250278.JQNQ01000001_gene3252	3.128e-07	61.0	2DR29@1|root,339VD@2|Bacteria,4NZEP@976|Bacteroidetes,1I852@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7054021_0	1123035.ARLA01000017_gene21	8.764e-12	78.0	2DR29@1|root,339VD@2|Bacteria,4NZEP@976|Bacteroidetes,1IM9I@117743|Flavobacteriia,4C2FH@83612|Psychroflexus	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7060988_0	313606.M23134_05227	6.627e-143	480.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
DTH2_k127_7060988_1	1121895.Q765_17450	3.136e-07	57.0	COG1361@1|root,COG1361@2|Bacteria,4NTTH@976|Bacteroidetes,1I4SJ@117743|Flavobacteriia,2P0UN@237|Flavobacterium	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7066608_1	459349.CLOAM0985	6.493e-31	141.0	COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_7066608_0	593750.Metfor_1140	9.748e-34	151.0	COG3291@1|root,arCOG02510@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF3344,PKD
DTH2_k127_7067063_0	1408433.JHXV01000018_gene3826	2.895e-131	449.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1I2PT@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
DTH2_k127_7079526_0	509191.AEDB02000022_gene2925	3.44e-93	326.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,3WIT1@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,Peptidase_S8,SLH
DTH2_k127_7116631_0	153721.MYP_579	5.846e-144	462.0	COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,47M2I@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
DTH2_k127_7116631_1	1123277.KB893194_gene5859	1.352e-88	298.0	COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,47KMH@768503|Cytophagia	976|Bacteroidetes	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
DTH2_k127_7116631_2	760192.Halhy_6041	2.242e-32	131.0	COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1IT8A@117747|Sphingobacteriia	976|Bacteroidetes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
DTH2_k127_7121064_2	641524.ADICYQ_2309	2.713e-07	57.0	COG2963@1|root,COG2963@2|Bacteria,4NZ21@976|Bacteroidetes	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
DTH2_k127_7121064_0	1123277.KB893183_gene99	1.172e-83	288.0	COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,47PZA@768503|Cytophagia	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
DTH2_k127_7121064_1	1454007.JAUG01000053_gene2497	2.845e-20	92.0	COG1262@1|root,COG1262@2|Bacteria,4NJRT@976|Bacteroidetes,1IVR7@117747|Sphingobacteriia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_7148798_3	446470.Snas_0537	8.694e-20	95.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
DTH2_k127_7148798_0	927658.AJUM01000022_gene1011	1.14e-133	445.0	COG3264@1|root,COG3264@2|Bacteria,4PMEF@976|Bacteroidetes,2G0S0@200643|Bacteroidia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
DTH2_k127_7148798_1	368407.Memar_1510	4.895e-104	349.0	COG2133@1|root,arCOG02796@2157|Archaea	2157|Archaea	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH2_k127_7148798_2	331678.Cphamn1_1489	7.783e-32	128.0	COG1765@1|root,COG1765@2|Bacteria,1FE41@1090|Chlorobi	1090|Chlorobi	O	PFAM OsmC family protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
DTH2_k127_7148798_4	459349.CLOAM1690	1.675e-12	71.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_7166385_0	1168034.FH5T_21195	2.986e-175	567.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,2G3GJ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_7166385_1	485918.Cpin_2225	1.11e-44	170.0	COG1629@1|root,COG4771@2|Bacteria,4PN7E@976|Bacteroidetes,1J0MG@117747|Sphingobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_7181849_0	385682.AFSL01000006_gene2356	6.726e-219	688.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,3XJBU@558415|Marinilabiliaceae	976|Bacteroidetes	F	IMP dehydrogenase / GMP reductase domain	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DTH2_k127_7181849_1	1237149.C900_03125	4.113e-70	245.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
DTH2_k127_7182559_1	926549.KI421517_gene1854	3.257e-19	96.0	COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia	976|Bacteroidetes	M	Domain of unknown function (DUF4292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
DTH2_k127_7182559_0	929556.Solca_4341	6.205e-115	389.0	COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,1IR0N@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
DTH2_k127_7194258_8	1120968.AUBX01000014_gene2256	3.305e-28	115.0	COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,47JDR@768503|Cytophagia	976|Bacteroidetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DTH2_k127_7194258_6	385682.AFSL01000062_gene1615	2.378e-37	147.0	2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,2FPFD@200643|Bacteroidia,3XJ9A@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4294
DTH2_k127_7194258_1	1168034.FH5T_12365	9.22e-141	461.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,2FMUQ@200643|Bacteroidia	976|Bacteroidetes	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
DTH2_k127_7194258_7	1408433.JHXV01000036_gene268	9.967e-29	128.0	2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes,1IAKI@117743|Flavobacteriia,2PB7R@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7194258_2	926562.Oweho_0901	2.302e-128	418.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,2PA4G@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH2_k127_7194258_5	886379.AEWI01000149_gene3375	1.862e-77	267.0	COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,2FSTZ@200643|Bacteroidia,3XJRJ@558415|Marinilabiliaceae	976|Bacteroidetes	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DTH2_k127_7194258_9	517418.Ctha_2265	1.703e-19	99.0	2E7E6@1|root,331X7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7194258_0	1313301.AUGC01000013_gene1275	3.226e-209	664.0	COG3186@1|root,COG3186@2|Bacteria,4NEX5@976|Bacteroidetes	976|Bacteroidetes	E	Pfam Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
DTH2_k127_7194258_3	1250278.JQNQ01000001_gene1528	1.141e-102	341.0	COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,1HWZA@117743|Flavobacteriia	976|Bacteroidetes	S	Conserved protein domain typically associated with flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DTH2_k127_7194258_4	1237149.C900_04904	1.123e-93	310.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,47KTT@768503|Cytophagia	976|Bacteroidetes	Q	fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
DTH2_k127_722320_0	1122176.KB903531_gene2986	1.78e-138	462.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_722320_1	760192.Halhy_6308	1.44e-10	71.0	2DTID@1|root,33KGU@2|Bacteria,4NZE6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7242271_5	1313421.JHBV01000009_gene4118	3.749e-41	152.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
DTH2_k127_7242271_0	1121129.KB903359_gene1546	8.724e-187	591.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,2FNW2@200643|Bacteroidia,22W99@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Imidazolone-5-propionate hydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DTH2_k127_7242271_3	700598.Niako_3251	2.363e-60	224.0	COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia	976|Bacteroidetes	DZ	Kelch repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG
DTH2_k127_7242271_2	459349.CLOAM1071	1.294e-68	259.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CARDB,Cadherin-like,DUF4091
DTH2_k127_7242271_6	48698.ENSPFOP00000023315	1.181e-19	104.0	KOG4292@1|root,KOG4292@2759|Eukaryota,3949K@33154|Opisthokonta,3BGFY@33208|Metazoa,3CUBZ@33213|Bilateria,48A9K@7711|Chordata,48V7Q@7742|Vertebrata,49ZX5@7898|Actinopterygii	33208|Metazoa	T	Cubilin (intrinsic factor-cobalamin receptor)	CUBN	GO:0000323,GO:0001701,GO:0001894,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005768,GO:0005773,GO:0005775,GO:0005783,GO:0005794,GO:0005798,GO:0005829,GO:0005886,GO:0005903,GO:0005905,GO:0006629,GO:0006725,GO:0006766,GO:0006767,GO:0006775,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0007154,GO:0007165,GO:0007275,GO:0007584,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0009056,GO:0009111,GO:0009235,GO:0009605,GO:0009607,GO:0009617,GO:0009790,GO:0009792,GO:0009897,GO:0009986,GO:0009987,GO:0009991,GO:0010008,GO:0012505,GO:0012506,GO:0015031,GO:0015833,GO:0015886,GO:0015889,GO:0015893,GO:0016020,GO:0016043,GO:0016192,GO:0016324,GO:0017038,GO:0017144,GO:0019439,GO:0019897,GO:0019898,GO:0020028,GO:0022607,GO:0023052,GO:0030135,GO:0030139,GO:0030492,GO:0030659,GO:0030666,GO:0031090,GO:0031232,GO:0031253,GO:0031410,GO:0031526,GO:0031667,GO:0031974,GO:0031982,GO:0032501,GO:0032502,GO:0032991,GO:0033013,GO:0033015,GO:0033036,GO:0033365,GO:0034381,GO:0034384,GO:0034613,GO:0034641,GO:0038023,GO:0038024,GO:0042221,GO:0042359,GO:0042365,GO:0042366,GO:0042493,GO:0042592,GO:0042737,GO:0042802,GO:0042803,GO:0042886,GO:0042953,GO:0042995,GO:0043009,GO:0043202,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044872,GO:0045177,GO:0045184,GO:0046483,GO:0046700,GO:0046983,GO:0048856,GO:0048871,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051186,GO:0051187,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0051704,GO:0051707,GO:0051716,GO:0060089,GO:0060249,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070062,GO:0070206,GO:0070207,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072594,GO:0097006,GO:0097708,GO:0098552,GO:0098588,GO:0098590,GO:0098657,GO:0098805,GO:0098862,GO:0120025,GO:0120038,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901615,GO:1901678,GO:1903561	-	ko:K14616	ko04977,map04977	-	-	-	ko00000,ko00001,ko04147	-	-	-	CUB,EGF,EGF_3,EGF_CA,hEGF
DTH2_k127_7242271_1	755732.Fluta_1682	1.717e-86	317.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_7242271_7	926562.Oweho_2246	1.98e-14	88.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4PPAH@976|Bacteroidetes,1IKHA@117743|Flavobacteriia,2PBN6@246874|Cryomorphaceae	2|Bacteria	M	Fibronectin type 3 domain	-	-	3.4.24.40	ko:K01406,ko:K20276	ko01503,ko02024,map01503,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CHU_C,Laminin_G_3,MAM,PKD
DTH2_k127_7242271_4	459349.CLOAM1071	2.457e-49	187.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CARDB,Cadherin-like,DUF4091
DTH2_k127_7254281_1	272556.CF65_00434	2.243e-06	59.0	COG3209@1|root,COG3501@1|root,COG3209@2|Bacteria,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Rhs Element Vgr Protein	vgrG	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF2345,Gp5_C,Phage_GPD
DTH2_k127_7254281_0	945713.IALB_3057	8.236e-271	850.0	COG1505@1|root,COG1505@2|Bacteria	2|Bacteria	E	serine-type exopeptidase activity	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH2_k127_7263281_1	1244869.H261_12684	1.047e-06	61.0	2EQWR@1|root,33IGI@2|Bacteria,1NNN3@1224|Proteobacteria,2UJW6@28211|Alphaproteobacteria,2JVIF@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7263281_0	468059.AUHA01000006_gene2877	5.063e-112	383.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1INUW@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_7292107_1	744872.Spica_2136	8.219e-117	384.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
DTH2_k127_7292107_3	1237149.C900_04481	1.525e-42	161.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,47QE4@768503|Cytophagia	976|Bacteroidetes	J	TIGRFAM endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH2_k127_7292107_0	1123277.KB893187_gene2796	4.473e-172	549.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47KCX@768503|Cytophagia	976|Bacteroidetes	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH2_k127_7292107_5	706587.Desti_5396	1.942e-10	63.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MQ6T@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
DTH2_k127_7292107_2	694427.Palpr_1799	1.216e-83	284.0	COG0785@1|root,COG0785@2|Bacteria,4PKGI@976|Bacteroidetes,2G3GF@200643|Bacteroidia,231NH@171551|Porphyromonadaceae	976|Bacteroidetes	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
DTH2_k127_7292107_4	1236508.BAKF01000005_gene655	1.029e-13	73.0	2E9PV@1|root,333W7@2|Bacteria,4NT8I@976|Bacteroidetes,2FT1D@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7314325_7	1408433.JHXV01000014_gene3628	2.245e-13	74.0	COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,1I840@117743|Flavobacteriia,2PBAC@246874|Cryomorphaceae	976|Bacteroidetes	Q	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_7314325_1	153721.MYP_4640	7.073e-242	769.0	COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,47JQ8@768503|Cytophagia	976|Bacteroidetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
DTH2_k127_7314325_4	485917.Phep_1203	8.62e-55	197.0	COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,1IRT0@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DTH2_k127_7314325_3	755732.Fluta_2440	1.592e-169	542.0	COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia,2PAIG@246874|Cryomorphaceae	976|Bacteroidetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DTH2_k127_7314325_0	1168034.FH5T_05025	3.322e-311	981.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
DTH2_k127_7314325_2	1408433.JHXV01000014_gene3647	1.778e-198	624.0	COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,1HY37@117743|Flavobacteriia,2PAGI@246874|Cryomorphaceae	976|Bacteroidetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DTH2_k127_7314325_5	742767.HMPREF9456_02020	7.873e-31	126.0	COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,2FSM9@200643|Bacteroidia,22Y41@171551|Porphyromonadaceae	976|Bacteroidetes	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
DTH2_k127_7314325_6	1254432.SCE1572_16810	2.805e-15	82.0	292FR@1|root,2ZPZX@2|Bacteria,1PBNW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7314325_8	1233950.IW22_03925	2.662e-08	59.0	2E347@1|root,32Y4A@2|Bacteria,4PKYE@976|Bacteroidetes,1IJHB@117743|Flavobacteriia,3ZS1E@59732|Chryseobacterium	976|Bacteroidetes	S	Secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7326507_0	593750.Metfor_1613	3.052e-203	638.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,2N9F3@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM CoA-binding domain protein	acdAB	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DTH2_k127_7337881_0	1484460.JSWG01000006_gene2963	3.851e-116	382.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia	976|Bacteroidetes	V	transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_7337881_1	1469557.JSWF01000035_gene938	1.289e-106	351.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HZ83@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_7359182_4	1121129.KB903374_gene551	8.364e-34	143.0	COG3203@1|root,COG3203@2|Bacteria,4NMHJ@976|Bacteroidetes,2FT17@200643|Bacteroidia,22YNX@171551|Porphyromonadaceae	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7359182_1	1047013.AQSP01000130_gene1864	6.771e-172	553.0	COG0591@1|root,COG0591@2|Bacteria,2NPAX@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
DTH2_k127_7359182_2	1121875.KB907546_gene2398	3.194e-171	559.0	COG2982@1|root,COG2982@2|Bacteria,4NHBK@976|Bacteroidetes,1I04H@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
DTH2_k127_7359182_3	945713.IALB_1969	3.723e-155	493.0	COG1023@1|root,COG1023@2|Bacteria	2|Bacteria	G	D-gluconate metabolic process	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
DTH2_k127_7359182_0	945713.IALB_1968	2.898e-262	817.0	COG0364@1|root,COG0364@2|Bacteria	2|Bacteria	G	glucose-6-phosphate dehydrogenase activity	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP1101	G6PD_C,G6PD_N
DTH2_k127_7372025_1	272562.CA_C2016	2.711e-38	148.0	COG1024@1|root,COG1024@2|Bacteria,1V884@1239|Firmicutes,24KIF@186801|Clostridia,36KER@31979|Clostridiaceae	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_7372025_3	1035196.HMPREF9998_00821	0.0002383	48.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,25RK6@186804|Peptostreptococcaceae	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
DTH2_k127_7372025_2	1246626.BleG1_2662	2.354e-34	141.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,1ZCKH@1386|Bacillus	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	fadB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_7372025_0	1163671.JAGI01000002_gene2426	1.989e-117	388.0	COG0332@1|root,COG0332@2|Bacteria,1VT7P@1239|Firmicutes,24FI1@186801|Clostridia,36H28@31979|Clostridiaceae	186801|Clostridia	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III
DTH2_k127_738048_4	1313421.JHBV01000027_gene1831	6.205e-78	265.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
DTH2_k127_738048_5	1408473.JHXO01000008_gene2915	8.203e-71	250.0	COG1577@1|root,COG1577@2|Bacteria,4NEXC@976|Bacteroidetes,2FXGS@200643|Bacteroidia	976|Bacteroidetes	I	mevalonate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_738048_2	1121931.AUHG01000010_gene648	5.129e-101	340.0	COG3407@1|root,COG3407@2|Bacteria,4NDYX@976|Bacteroidetes,1HY6U@117743|Flavobacteriia	976|Bacteroidetes	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DTH2_k127_738048_3	869213.JCM21142_41739	1.189e-99	334.0	COG1577@1|root,COG1577@2|Bacteria,4NDYJ@976|Bacteroidetes,47USX@768503|Cytophagia	976|Bacteroidetes	I	mevalonate kinase	mvaK	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH2_k127_738048_1	1408433.JHXV01000028_gene2114	1.814e-129	422.0	COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,1HY6T@117743|Flavobacteriia,2PAHB@246874|Cryomorphaceae	976|Bacteroidetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
DTH2_k127_738048_0	1237149.C900_04358	2.534e-209	663.0	COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,47KX0@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
DTH2_k127_738048_6	927658.AJUM01000037_gene1933	2.595e-27	113.0	COG0640@1|root,COG0640@2|Bacteria,4NSQD@976|Bacteroidetes,2FUJ6@200643|Bacteroidia,3XK8K@558415|Marinilabiliaceae	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DTH2_k127_738048_7	1121011.AUCB01000003_gene2681	2.763e-13	70.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,23GN1@178469|Arenibacter	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DTH2_k127_7386196_9	1168034.FH5T_03525	2.702e-53	198.0	COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_7386196_8	1168034.FH5T_03520	8.427e-58	214.0	COG3206@1|root,COG3206@2|Bacteria,4NSFM@976|Bacteroidetes	976|Bacteroidetes	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7386196_5	926562.Oweho_1845	1.755e-91	312.0	COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1I785@117743|Flavobacteriia,2PAYX@246874|Cryomorphaceae	976|Bacteroidetes	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
DTH2_k127_7386196_4	1168034.FH5T_06745	2.687e-129	429.0	COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,2G3BA@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_7386196_3	269798.CHU_0928	7.661e-131	427.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,47KRN@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH2_k127_7386196_1	929556.Solca_4039	3.603e-171	548.0	COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DTH2_k127_7386196_12	1346330.M472_07780	5.251e-11	74.0	28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,1IPQD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7386196_7	709991.Odosp_3159	5.51e-72	247.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,22WJC@171551|Porphyromonadaceae	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DTH2_k127_7386196_11	1313301.AUGC01000021_gene1228	3.432e-19	89.0	2E3BI@1|root,32YB0@2|Bacteria,4NWRS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OST-HTH
DTH2_k127_7386196_6	573370.DMR_23240	1.393e-72	255.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2M9EG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
DTH2_k127_7386196_0	700598.Niako_5074	3.84e-178	568.0	COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DTH2_k127_7386196_10	694427.Palpr_0029	1.788e-52	189.0	COG1225@1|root,COG1225@2|Bacteria,4NQCB@976|Bacteroidetes,2FXA6@200643|Bacteroidia	976|Bacteroidetes	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH2_k127_7386196_2	1408473.JHXO01000001_gene2047	1.87e-141	457.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,2FNUY@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_7392876_1	1121129.KB903374_gene581	7.858e-86	288.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,22WBU@171551|Porphyromonadaceae	976|Bacteroidetes	C	2-oxoacid acceptor oxidoreductase, alpha subunit	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH2_k127_7392876_0	1408473.JHXO01000004_gene145	1.694e-134	436.0	COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia	976|Bacteroidetes	C	ferredoxin oxidoreductase, subunit beta	oorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_7392876_2	1121904.ARBP01000004_gene992	3.326e-10	62.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
DTH2_k127_7448830_3	1237149.C900_02777	4.712e-76	265.0	COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	fjo11	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_7448830_5	886379.AEWI01000023_gene14	1.297e-34	136.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,2G2BE@200643|Bacteroidia,3XK8X@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal prokaryotic L21 protein	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
DTH2_k127_7448830_4	1538644.KO02_06240	3.382e-39	147.0	COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,1IT8M@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DTH2_k127_7448830_0	929556.Solca_3281	8.67e-179	571.0	COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia	976|Bacteroidetes	J	seryl-tRNA synthetase	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DTH2_k127_7448830_1	1313421.JHBV01000024_gene4970	4.046e-128	432.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE2V@976|Bacteroidetes,1INS7@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6,TPR_8
DTH2_k127_7448830_2	435591.BDI_2584	4.669e-90	303.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,2FMH1@200643|Bacteroidia,22WN1@171551|Porphyromonadaceae	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DTH2_k127_7450091_0	1453500.AT05_00730	9.168e-131	439.0	COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_7473414_2	880073.Calab_3801	6.926e-12	68.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7473414_0	909663.KI867150_gene1147	2.096e-61	220.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,42T3V@68525|delta/epsilon subdivisions,2X2EJ@28221|Deltaproteobacteria,2MSD1@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
DTH2_k127_7477246_0	768704.Desmer_0311	1.337e-81	280.0	COG0697@1|root,COG0697@2|Bacteria,1V009@1239|Firmicutes,24DF1@186801|Clostridia,264VJ@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH2_k127_7477246_6	525257.HMPREF0204_10345	8.328e-05	56.0	COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia,3ZRH6@59732|Chryseobacterium	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
DTH2_k127_7477246_4	313606.M23134_05970	2.413e-16	94.0	COG1520@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG4447@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4447@2|Bacteria,4PME7@976|Bacteroidetes,47Y2P@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7477246_5	880073.Calab_1754	2.725e-11	77.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
DTH2_k127_7477246_2	459349.CLOAM1622	3.095e-59	231.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM
DTH2_k127_7477246_1	1239962.C943_01492	4.215e-60	214.0	2CCNY@1|root,2Z877@2|Bacteria,4NR3D@976|Bacteroidetes	976|Bacteroidetes	E	CpeT/CpcT family (DUF1001)	-	-	-	-	-	-	-	-	-	-	-	-	CpeT
DTH2_k127_7477246_3	457424.BFAG_03347	1.254e-27	117.0	COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,2G2UX@200643|Bacteroidia,4AW56@815|Bacteroidaceae	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
DTH2_k127_7488476_0	1232437.KL662028_gene2806	1.505e-66	229.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,42P5R@68525|delta/epsilon subdivisions,2WJDU@28221|Deltaproteobacteria,2MI4P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH2_k127_7488476_1	1121100.JCM6294_3003	7.198e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,4NQW2@976|Bacteroidetes,2FREW@200643|Bacteroidia,4APP7@815|Bacteroidaceae	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_7489616_0	1121904.ARBP01000005_gene4665	1.011e-84	286.0	COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,47NPV@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
DTH2_k127_7489616_1	1041146.ATZB01000023_gene2673	4.041e-70	246.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
DTH2_k127_7495830_7	101510.RHA1_ro04285	1.723e-08	58.0	COG0628@1|root,COG0628@2|Bacteria,2GM01@201174|Actinobacteria,4FXD0@85025|Nocardiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_7495830_4	693979.Bache_1117	2.047e-81	278.0	COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,2FN9G@200643|Bacteroidia,4AKPN@815|Bacteroidaceae	976|Bacteroidetes	J	ribosomal pseudouridine synthase C, large subunit	rluC	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
DTH2_k127_7495830_5	1121104.AQXH01000001_gene1193	7.677e-74	258.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH2_k127_7495830_8	509635.N824_02670	2.593e-06	55.0	2EK3P@1|root,33DU3@2|Bacteria,4NW5T@976|Bacteroidetes,1IUB3@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4296
DTH2_k127_7495830_0	886379.AEWI01000023_gene8	7.086e-316	981.0	COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia,3XJ41@558415|Marinilabiliaceae	976|Bacteroidetes	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
DTH2_k127_7495830_2	521097.Coch_1665	3.37e-125	408.0	COG0794@1|root,COG2905@1|root,COG0794@2|Bacteria,COG2905@2|Bacteria,4NED8@976|Bacteroidetes,1HXYH@117743|Flavobacteriia,1EQR8@1016|Capnocytophaga	976|Bacteroidetes	MT	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
DTH2_k127_7495830_1	1121129.KB903367_gene2861	5.065e-190	621.0	COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,2FMTK@200643|Bacteroidia,22WRF@171551|Porphyromonadaceae	976|Bacteroidetes	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_7495830_3	1408473.JHXO01000010_gene3560	2.212e-118	384.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,2FKZE@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
DTH2_k127_7495830_6	1008457.BAEX01000058_gene405	7.711e-50	178.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,1HX3I@117743|Flavobacteriia,47H35@76831|Myroides	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH2_k127_7507851_8	1408473.JHXO01000008_gene2782	4.905e-13	70.0	COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_7,TPR_8
DTH2_k127_7507851_2	742726.HMPREF9448_00415	1.841e-111	368.0	COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,2FN5I@200643|Bacteroidia,22VZZ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
DTH2_k127_7507851_7	755732.Fluta_3589	1.022e-30	123.0	COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1I43K@117743|Flavobacteriia,2PB3N@246874|Cryomorphaceae	976|Bacteroidetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH2_k127_7507851_4	700598.Niako_7006	4.012e-66	231.0	COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1IS50@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DNA glycosylase MPG family	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DTH2_k127_7507851_0	927658.AJUM01000017_gene3131	7.29e-213	679.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,2FMT4@200643|Bacteroidia,3XJ5D@558415|Marinilabiliaceae	976|Bacteroidetes	L	RecQ zinc-binding	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
DTH2_k127_7507851_3	331113.SNE_A07170	1.601e-74	260.0	COG1597@1|root,COG1597@2|Bacteria,2JH3J@204428|Chlamydiae	204428|Chlamydiae	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_7507851_6	385682.AFSL01000069_gene1483	4.484e-31	131.0	2B5KV@1|root,31YFX@2|Bacteria,4NQRP@976|Bacteroidetes,2FY4M@200643|Bacteroidia,3XJRV@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7507851_1	517418.Ctha_0865	3.968e-123	408.0	COG0668@1|root,COG0668@2|Bacteria,1FD89@1090|Chlorobi	1090|Chlorobi	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
DTH2_k127_7507851_5	1121896.JMLU01000057_gene117	2.985e-32	132.0	2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,1IERS@117743|Flavobacteriia,2NZA8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7512976_0	1121904.ARBP01000003_gene6356	1.553e-177	593.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_7525678_6	1094466.KQS_09730	6.434e-06	48.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,1I30B@117743|Flavobacteriia,2NWB5@237|Flavobacterium	976|Bacteroidetes	I	Biotin-requiring enzyme	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
DTH2_k127_7525678_3	926549.KI421517_gene2900	3.969e-65	228.0	COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,47P6H@768503|Cytophagia	976|Bacteroidetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
DTH2_k127_7525678_0	525373.HMPREF0766_11560	6.248e-117	383.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes,1IPDS@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
DTH2_k127_7525678_2	1239962.C943_01092	1.968e-83	286.0	COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,47NUX@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_7525678_4	1296416.JACB01000015_gene4713	2.393e-58	207.0	COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1I198@117743|Flavobacteriia,2YGTV@290174|Aquimarina	976|Bacteroidetes	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
DTH2_k127_7525678_1	468059.AUHA01000004_gene2169	6.419e-104	346.0	COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,1INNA@117747|Sphingobacteriia	976|Bacteroidetes	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
DTH2_k127_7525678_5	742817.HMPREF9449_01741	1.068e-09	64.0	2ACZI@1|root,312MC@2|Bacteria,4PHKN@976|Bacteroidetes,2G1IY@200643|Bacteroidia,22Z1T@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7531320_4	643648.Slip_1864	2.525e-08	55.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42JMC@68298|Syntrophomonadaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH2_k127_7531320_1	1408473.JHXO01000001_gene2523	1.396e-70	247.0	COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,2FNX7@200643|Bacteroidia	976|Bacteroidetes	S	Phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH2_k127_7531320_0	743722.Sph21_3096	7.931e-101	333.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQ3T@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH2_k127_7531320_3	468059.AUHA01000006_gene2852	7.823e-25	108.0	COG3577@1|root,COG3577@2|Bacteria,4PGFR@976|Bacteroidetes,1ITP7@117747|Sphingobacteriia	976|Bacteroidetes	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
DTH2_k127_7531320_2	517418.Ctha_2076	1.723e-46	195.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1FF5N@1090|Chlorobi	1090|Chlorobi	U	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7541946_4	945713.IALB_1822	3.511e-60	234.0	COG1470@1|root,COG1572@1|root,COG2911@1|root,COG3391@1|root,COG4412@1|root,COG1470@2|Bacteria,COG1572@2|Bacteria,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	mxcI	-	3.4.21.50	ko:K01337,ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CarboxypepD_reg,DUF1929,F5_F8_type_C,FlgD_ig
DTH2_k127_7541946_2	1223410.KN050846_gene1957	1.368e-86	300.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
DTH2_k127_7541946_8	1178825.ALIH01000001_gene2303	0.0004981	44.0	28JFU@1|root,2Z99Q@2|Bacteria,4NJ9K@976|Bacteroidetes,1HYW4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7541946_7	926562.Oweho_3448	1.01e-29	129.0	28JFU@1|root,30YB4@2|Bacteria,4PC31@976|Bacteroidetes,1ICTS@117743|Flavobacteriia,2PC4T@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7541946_6	1408473.JHXO01000005_gene1690	7.16e-38	157.0	COG1193@1|root,COG1193@2|Bacteria,4NNNV@976|Bacteroidetes,2FMM1@200643|Bacteroidia	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2027,Smr
DTH2_k127_7541946_5	886379.AEWI01000046_gene3121	3.096e-54	197.0	COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,2FSA6@200643|Bacteroidia,3XIYV@558415|Marinilabiliaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_7541946_3	880073.Calab_0191	9.56e-73	254.0	2AMSR@1|root,31CP7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7541946_0	926549.KI421517_gene119	1.662e-281	895.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_7541946_1	926562.Oweho_1341	4.657e-107	361.0	COG2304@1|root,COG2304@2|Bacteria,4NJF1@976|Bacteroidetes,1I5HE@117743|Flavobacteriia,2PAI7@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
DTH2_k127_7543677_7	946077.W5A_08622	7.103e-18	85.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1I2VR@117743|Flavobacteriia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DTH2_k127_7543677_3	1408433.JHXV01000034_gene33	1.016e-60	211.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1I22S@117743|Flavobacteriia,2PATX@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DTH2_k127_7543677_6	1408433.JHXV01000034_gene32	5.048e-38	143.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1I2TE@117743|Flavobacteriia,2PAYV@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DTH2_k127_7543677_8	1408473.JHXO01000006_gene1290	3.651e-09	59.0	COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,2FUJB@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DTH2_k127_7543677_2	908612.HMPREF9720_2533	2.216e-69	237.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,22UEK@171550|Rikenellaceae	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DTH2_k127_7543677_1	1408433.JHXV01000034_gene29	1.597e-110	361.0	COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1HXI0@117743|Flavobacteriia,2PAJY@246874|Cryomorphaceae	976|Bacteroidetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DTH2_k127_7543677_4	1168289.AJKI01000011_gene468	8.179e-48	175.0	COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,2FS3J@200643|Bacteroidia,3XJZ0@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein L22p/L17e	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DTH2_k127_7543677_5	391603.FBALC1_13412	4.538e-44	161.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,1I2W9@117743|Flavobacteriia	976|Bacteroidetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DTH2_k127_7543677_0	385682.AFSL01000026_gene646	4.026e-131	422.0	COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,2FN89@200643|Bacteroidia,3XJ6G@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal Proteins L2, C-terminal domain	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DTH2_k127_7546821_0	945713.IALB_1831	4.05e-103	369.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
DTH2_k127_7546821_3	242619.PG_0232	2.088e-11	78.0	COG2866@1|root,COG3291@1|root,COG2866@2|Bacteria,COG3291@2|Bacteria,4NGV7@976|Bacteroidetes,2FRH7@200643|Bacteroidia,230R0@171551|Porphyromonadaceae	976|Bacteroidetes	E	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,PKD,Peptidase_M14
DTH2_k127_7546821_2	1349785.BAUG01000022_gene1421	1.211e-17	98.0	COG3023@1|root,COG3291@1|root,COG4935@1|root,COG3023@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	fpp1	-	-	-	-	-	-	-	-	-	-	-	CUB,MAM,P_proprotein,Reprolysin_4,fn3
DTH2_k127_7546821_1	1122176.KB903619_gene5403	3.571e-26	126.0	COG1361@1|root,COG1361@2|Bacteria,4NKYJ@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Peptidase_M43,Reprolysin_3,fn3
DTH2_k127_7611434_2	1168034.FH5T_02865	4.259e-52	189.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,2FUT5@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
DTH2_k127_7611434_0	1408473.JHXO01000003_gene2574	0.0	1083.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 3	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
DTH2_k127_7611434_1	929556.Solca_4100	5.335e-295	923.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DTH2_k127_7621639_6	6238.CBG10573	4.19e-06	49.0	28PU1@1|root,2QWGN@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	C2
DTH2_k127_7621639_5	1004149.AFOE01000009_gene2159	1.082e-20	98.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH2_k127_7621639_1	709991.Odosp_2805	1.985e-221	697.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,2FNAX@200643|Bacteroidia,22W4G@171551|Porphyromonadaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DTH2_k127_7621639_3	1408813.AYMG01000027_gene5368	2.659e-109	364.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1IQW6@117747|Sphingobacteriia	976|Bacteroidetes	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
DTH2_k127_7621639_2	1408473.JHXO01000006_gene1096	1.299e-134	437.0	COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,2FNHU@200643|Bacteroidia	976|Bacteroidetes	E	Lao Ao transport system ATPase	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DTH2_k127_7621639_0	866536.Belba_3140	0.0	1157.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47ME1@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH2_k127_7621639_4	929703.KE386491_gene2154	2.635e-45	169.0	COG1595@1|root,COG1595@2|Bacteria,4NQC9@976|Bacteroidetes,47QM4@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_7644176_3	1211813.CAPH01000009_gene254	1.9e-58	205.0	COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,2FMSR@200643|Bacteroidia,22VRM@171550|Rikenellaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH2_k127_7644176_1	1185876.BN8_05445	2.366e-115	381.0	COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,47MND@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DTH2_k127_7644176_5	1122176.KB903561_gene3586	1.567e-51	188.0	COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_7644176_0	1123248.KB893348_gene194	7.406e-187	618.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,1IWR7@117747|Sphingobacteriia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
DTH2_k127_7644176_2	1122176.KB903561_gene3588	3.297e-75	260.0	COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,1ISF2@117747|Sphingobacteriia	976|Bacteroidetes	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH2_k127_7644176_6	485918.Cpin_6314	1.691e-18	91.0	2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_4
DTH2_k127_7644176_7	616991.JPOO01000001_gene2932	3.953e-10	66.0	2E3Q9@1|root,32YN7@2|Bacteria,4NWH3@976|Bacteroidetes,1I61D@117743|Flavobacteriia	976|Bacteroidetes	S	tRNA_anti-like	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-like
DTH2_k127_7644176_4	1279009.ADICEAN_02198	1.63e-52	191.0	COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH2_k127_7644176_8	309799.DICTH_0320	2.879e-08	63.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
DTH2_k127_7659434_0	1408433.JHXV01000007_gene2882	5.571e-43	178.0	28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,1I8D6@117743|Flavobacteriia,2PARN@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7659434_2	869213.JCM21142_31186	8.746e-36	148.0	COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia	976|Bacteroidetes	S	PFAM PASTA domain	spk1	-	2.7.11.1,6.3.2.4	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01001,ko01011	-	-	-	PASTA
DTH2_k127_7659434_1	485918.Cpin_5946	7.365e-42	157.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,1INQY@117747|Sphingobacteriia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DTH2_k127_7664017_1	716544.wcw_1471	3.73e-83	284.0	COG0183@1|root,COG0183@2|Bacteria,2JFTV@204428|Chlamydiae	204428|Chlamydiae	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
DTH2_k127_7664017_0	716544.wcw_1472	8.77e-97	332.0	COG1250@1|root,COG1250@2|Bacteria,2JFTQ@204428|Chlamydiae	204428|Chlamydiae	C	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
DTH2_k127_7664017_2	1151292.QEW_1452	5.364e-45	167.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DTH2_k127_7669399_1	886379.AEWI01000081_gene1968	6.915e-44	162.0	COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,2FSSJ@200643|Bacteroidia,3XJYQ@558415|Marinilabiliaceae	976|Bacteroidetes	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
DTH2_k127_7669399_0	1168034.FH5T_15225	3.971e-54	192.0	COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,2FTH2@200643|Bacteroidia	976|Bacteroidetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
DTH2_k127_7669717_1	1121904.ARBP01000011_gene1396	4.693e-24	116.0	COG1404@1|root,COG1572@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_7669717_3	1225184.ALXE01000068_gene364	0.000171	44.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,3VY25@53335|Pantoea	1236|Gammaproteobacteria	O	Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade	comM	GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH2_k127_7669717_2	1191523.MROS_0879	2.363e-07	64.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	pemA	GO:0005575,GO:0005576	3.1.1.11	ko:K01051,ko:K10297	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko04121	-	-	-	Beta_helix,Pectinesterase,Pkinase
DTH2_k127_7669717_0	1434325.AZQN01000006_gene3287	1.265e-94	329.0	2C5G3@1|root,2Z8TT@2|Bacteria,4P166@976|Bacteroidetes,47TW0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7690698_5	1384056.N787_03150	9.135e-11	65.0	2DNQI@1|root,32YKA@2|Bacteria,1QD0W@1224|Proteobacteria,1T8VG@1236|Gammaproteobacteria,1XBAG@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7690698_2	748247.AZKH_4441	1.993e-44	165.0	COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,2VSIB@28216|Betaproteobacteria,2KYQ7@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH2_k127_7690698_1	1379698.RBG1_1C00001G0669	6.905e-45	171.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	Peptidase_M56
DTH2_k127_7690698_4	449447.MAE_57720	1.582e-11	67.0	COG1598@1|root,COG1598@2|Bacteria,1GF2K@1117|Cyanobacteria	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
DTH2_k127_7690698_3	247490.KSU1_D0749	8.636e-14	71.0	COG0551@1|root,COG0551@2|Bacteria,2J0R7@203682|Planctomycetes	203682|Planctomycetes	L	PFAM DNA topoisomerase type IA zn finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726,zf-C4_Topoisom
DTH2_k127_7690698_0	1198232.CYCME_0125	1.035e-56	203.0	COG0551@1|root,COG0551@2|Bacteria,1RJ5B@1224|Proteobacteria,1S349@1236|Gammaproteobacteria,4616Z@72273|Thiotrichales	72273|Thiotrichales	M	Protein of unknown function (DUF2726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
DTH2_k127_7726732_1	742725.HMPREF9450_00762	1.428e-22	98.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,2FTIA@200643|Bacteroidia,22VQ1@171550|Rikenellaceae	976|Bacteroidetes	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DTH2_k127_7726732_0	1121373.KB903645_gene3356	6.513e-175	562.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
DTH2_k127_7746867_0	886379.AEWI01000013_gene2054	2.061e-303	951.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia,3XIM1@558415|Marinilabiliaceae	976|Bacteroidetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH2_k127_7746867_1	575540.Isop_0296	3.071e-51	187.0	COG0259@1|root,COG0259@2|Bacteria,2IYY9@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
DTH2_k127_7753280_0	926562.Oweho_2593	0.0	1383.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1HXC3@117743|Flavobacteriia,2PAKG@246874|Cryomorphaceae	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
DTH2_k127_7753280_2	945713.IALB_1831	6.84e-111	396.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
DTH2_k127_7753280_5	313606.M23134_00105	8.551e-42	178.0	COG1649@1|root,COG3291@1|root,COG4733@1|root,COG1649@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NJK3@976|Bacteroidetes,47TYM@768503|Cytophagia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43
DTH2_k127_7753280_3	1453500.AT05_06400	2.016e-87	294.0	COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,1HXVS@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DTH2_k127_7753280_4	643867.Ftrac_1841	6.948e-58	209.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,47Q1Q@768503|Cytophagia	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
DTH2_k127_7753280_1	1121904.ARBP01000020_gene2818	2.124e-111	367.0	COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia	976|Bacteroidetes	O	membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH2_k127_7753280_6	485918.Cpin_1881	8.418e-10	59.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,1IUPB@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
DTH2_k127_7761945_1	714943.Mucpa_1462	1.446e-60	214.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
DTH2_k127_7761945_2	398720.MED217_15980	1.465e-33	139.0	COG0810@1|root,COG0810@2|Bacteria,4NG4I@976|Bacteroidetes,1HX6B@117743|Flavobacteriia,2XIT5@283735|Leeuwenhoekiella	976|Bacteroidetes	M	TonB family domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
DTH2_k127_7761945_3	1347342.BN863_27840	5.385e-29	120.0	COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia	976|Bacteroidetes	U	Biopolymer transport protein	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH2_k127_7761945_0	1408473.JHXO01000004_gene165	6.121e-81	276.0	COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,2FNG0@200643|Bacteroidia	976|Bacteroidetes	U	MotA TolQ ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_7761945_4	1122179.KB890415_gene2042	2.608e-23	115.0	COG2304@1|root,COG2304@2|Bacteria,4PKD0@976|Bacteroidetes,1IXV1@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
DTH2_k127_7770754_0	1163617.SCD_n02891	4.915e-182	579.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
DTH2_k127_7770754_1	395493.BegalDRAFT_2017	5.572e-46	179.0	COG0392@1|root,COG0392@2|Bacteria,1PPT2@1224|Proteobacteria,1SS9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
DTH2_k127_7770754_2	323259.Mhun_3122	8.195e-32	138.0	arCOG10338@1|root,arCOG10338@2157|Archaea	2157|Archaea	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_7788567_1	313606.M23134_00674	7.223e-103	355.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
DTH2_k127_7788567_4	357808.RoseRS_4272	1.838e-26	125.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7788567_5	1453498.LG45_00925	5.381e-05	56.0	COG3420@1|root,COG3420@2|Bacteria,4PJ27@976|Bacteroidetes,1IDUT@117743|Flavobacteriia,2NZ9E@237|Flavobacterium	976|Bacteroidetes	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7788567_0	1408433.JHXV01000018_gene3795	9.265e-194	646.0	COG0265@1|root,COG3673@1|root,COG4412@1|root,COG0265@2|Bacteria,COG3673@2|Bacteria,COG4412@2|Bacteria,4PNUK@976|Bacteroidetes,1IKEA@117743|Flavobacteriia,2PA7S@246874|Cryomorphaceae	976|Bacteroidetes	O	Peptide-N-glycosidase F, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,N-glycanase_C
DTH2_k127_7788567_2	929556.Solca_2394	4.651e-99	348.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg,TPR_12,TPR_8
DTH2_k127_7788567_6	121225.PHUM125620-PA	0.0005826	50.0	COG3340@1|root,2QR7X@2759|Eukaryota,39DGA@33154|Opisthokonta,3BC18@33208|Metazoa,3CWYN@33213|Bilateria,41WW9@6656|Arthropoda,3SKC9@50557|Insecta	33208|Metazoa	E	Serine-type peptidase activity. It is involved in the biological process described with proteolysis	-	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
DTH2_k127_7788567_3	1122176.KB903587_gene4371	6.326e-52	190.0	COG2197@1|root,COG2197@2|Bacteria,4NQNY@976|Bacteroidetes,1IY32@117747|Sphingobacteriia	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_7808035_0	1120966.AUBU01000013_gene473	0.0	1284.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47JGB@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DTH2_k127_7808035_1	1121396.KB893063_gene1211	4.77e-20	95.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MJ5Q@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
DTH2_k127_7835998_0	927658.AJUM01000037_gene2274	1.397e-221	692.0	COG2403@1|root,COG2403@2|Bacteria,4NHIW@976|Bacteroidetes,2FNNX@200643|Bacteroidia	976|Bacteroidetes	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7835998_2	1408473.JHXO01000008_gene2889	2.132e-25	112.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,2FN06@200643|Bacteroidia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_7835998_1	1433126.BN938_2590	1.219e-161	518.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,2FN06@200643|Bacteroidia,22U4V@171550|Rikenellaceae	976|Bacteroidetes	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_7839639_2	1408473.JHXO01000012_gene284	1.147e-86	295.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes	976|Bacteroidetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DTH2_k127_7839639_1	869213.JCM21142_31221	3.598e-107	355.0	COG1622@1|root,COG1622@2|Bacteria,4PICF@976|Bacteroidetes,47VTZ@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	COX2,COX2_TM,Cytochrom_C
DTH2_k127_7839639_5	880073.Calab_0301	0.0006148	46.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
DTH2_k127_7839639_4	1191523.MROS_0037	6.64e-66	231.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH2_k127_7839639_0	1191523.MROS_0038	2.721e-250	781.0	COG0843@1|root,COG0843@2|Bacteria	2|Bacteria	C	heme-copper terminal oxidase activity	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DTH2_k127_7839639_3	1168034.FH5T_09785	3.865e-71	248.0	COG1999@1|root,COG1999@2|Bacteria,4NU1J@976|Bacteroidetes,2FXFP@200643|Bacteroidia	976|Bacteroidetes	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH2_k127_7860607_0	1122225.AULQ01000002_gene645	4.015e-72	269.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
DTH2_k127_7865750_0	926562.Oweho_1492	5.686e-212	674.0	COG1132@1|root,COG1132@2|Bacteria,4PKCT@976|Bacteroidetes,1HYJM@117743|Flavobacteriia,2PAJ2@246874|Cryomorphaceae	976|Bacteroidetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DTH2_k127_7865750_4	694427.Palpr_0119	5.45e-52	199.0	COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,2FUAF@200643|Bacteroidia,230JJ@171551|Porphyromonadaceae	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH2_k127_7865750_1	1168034.FH5T_15170	5.952e-128	424.0	COG4775@1|root,COG4775@2|Bacteria,4NMIQ@976|Bacteroidetes,2FS3R@200643|Bacteroidia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
DTH2_k127_7865750_2	435591.BDI_3032	1.923e-86	291.0	COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,22WSM@171551|Porphyromonadaceae	976|Bacteroidetes	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
DTH2_k127_7865750_3	251221.35213174	1.117e-58	212.0	COG1216@1|root,COG1216@2|Bacteria,1G6GW@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7865750_5	357808.RoseRS_0220	3.003e-49	184.0	COG0451@1|root,COG0451@2|Bacteria,2GAZF@200795|Chloroflexi,374ZI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD
DTH2_k127_7873448_3	1123248.KB893325_gene1143	6.829e-48	175.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1IP7B@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DTH2_k127_7873448_2	1408473.JHXO01000001_gene2375	7.225e-112	377.0	COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,2FNCN@200643|Bacteroidia	976|Bacteroidetes	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_7873448_1	1408473.JHXO01000001_gene2374	4.705e-116	377.0	COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,2FMCD@200643|Bacteroidia	976|Bacteroidetes	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
DTH2_k127_7873448_0	929713.NIASO_07200	2.269e-217	677.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1IP4R@117747|Sphingobacteriia	976|Bacteroidetes	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_7879212_3	762903.Pedsa_0243	5.392e-58	205.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1IQGU@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
DTH2_k127_7879212_1	1121129.KB903371_gene205	1.073e-127	415.0	COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,2FMHI@200643|Bacteroidia,22VZA@171551|Porphyromonadaceae	976|Bacteroidetes	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH2_k127_7879212_0	926562.Oweho_2434	1.074e-140	479.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1I8HX@117743|Flavobacteriia,2PAB4@246874|Cryomorphaceae	976|Bacteroidetes	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
DTH2_k127_7879212_2	929556.Solca_4334	3.614e-75	258.0	COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Phosphoribosyl transferase domain	comF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Pribosyltran
DTH2_k127_7879212_4	1285586.H131_05858	2.243e-17	83.0	COG1123@1|root,COG4172@2|Bacteria,1UZK8@1239|Firmicutes,4HTUD@91061|Bacilli,3IWIB@400634|Lysinibacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K02031,ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
DTH2_k127_7886502_1	485918.Cpin_6843	4.619e-26	113.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
DTH2_k127_7886502_0	1122605.KB893647_gene259	1.806e-55	207.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1ISZA@117747|Sphingobacteriia	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
DTH2_k127_7886502_2	306281.AJLK01000172_gene5174	1.443e-17	87.0	COG4704@1|root,COG4704@2|Bacteria,1G7Y9@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
DTH2_k127_7897362_0	457570.Nther_0354	3.967e-17	95.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Beta_helix
DTH2_k127_7899776_0	1122919.KB905605_gene4569	4.587e-05	56.0	COG1649@1|root,COG1649@2|Bacteria,1UNKI@1239|Firmicutes,4IUH8@91061|Bacilli,277KZ@186822|Paenibacillaceae	91061|Bacilli	S	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6
DTH2_k127_790000_3	945713.IALB_1497	2.813e-41	162.0	2AX7X@1|root,31P6Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_790000_4	945713.IALB_1498	1.925e-22	102.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
DTH2_k127_790000_2	927658.AJUM01000034_gene116	1.972e-79	273.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,3XIQ9@558415|Marinilabiliaceae	976|Bacteroidetes	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
DTH2_k127_790000_0	1168289.AJKI01000031_gene1020	2.473e-128	419.0	COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,2FMW2@200643|Bacteroidia,3XIS1@558415|Marinilabiliaceae	976|Bacteroidetes	S	NIF3 (NGG1p interacting factor 3)	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
DTH2_k127_790000_1	1123248.KB893321_gene534	3.639e-87	298.0	COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,1IQ8A@117747|Sphingobacteriia	976|Bacteroidetes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
DTH2_k127_7940515_1	385682.AFSL01000047_gene523	5.009e-106	348.0	COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,3XIVK@558415|Marinilabiliaceae	976|Bacteroidetes	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DTH2_k127_7940515_0	1349822.NSB1T_11210	6.079e-120	389.0	COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia,22W4A@171551|Porphyromonadaceae	976|Bacteroidetes	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DTH2_k127_7956005_0	1229276.DI53_1292	1.572e-81	274.0	28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,1IPH6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7956005_1	1123278.KB893546_gene5008	1.243e-47	184.0	COG3528@1|root,COG3528@2|Bacteria,4NHTR@976|Bacteroidetes,47QXG@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
DTH2_k127_7958514_0	755732.Fluta_0703	1.362e-134	454.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7977205_1	1316936.K678_12112	0.0006831	50.0	COG2755@1|root,COG2755@2|Bacteria,1NYIK@1224|Proteobacteria,2UT1R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7977205_0	1232410.KI421412_gene220	3.513e-267	834.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria,43U63@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
DTH2_k127_7979181_2	1178825.ALIH01000002_gene912	2.373e-09	67.0	COG0457@1|root,COG0457@2|Bacteria,4NF0N@976|Bacteroidetes,1HWJF@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_7979181_0	869213.JCM21142_439	4.286e-225	722.0	COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia	976|Bacteroidetes	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH2_k127_7979181_1	376686.Fjoh_0331	2.377e-145	464.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1HWWH@117743|Flavobacteriia,2NS8M@237|Flavobacterium	976|Bacteroidetes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_7990772_1	435591.BDI_3604	3.847e-39	151.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,2FMGW@200643|Bacteroidia,22WSS@171551|Porphyromonadaceae	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH2_k127_7990772_0	1453500.AT05_00255	2.974e-70	247.0	COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,1HX94@117743|Flavobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K09650	-	-	-	-	ko00000,ko01000,ko01002,ko03029	-	-	-	Rhomboid
DTH2_k127_7990772_2	1279009.ADICEAN_03598	1.779e-27	117.0	COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,47KZU@768503|Cytophagia	976|Bacteroidetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH2_k127_7991465_1	313606.M23134_00148	1.395e-28	135.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_7991465_2	1122176.KB903619_gene5403	1.244e-24	122.0	COG1361@1|root,COG1361@2|Bacteria,4NKYJ@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Peptidase_M43,Reprolysin_3,fn3
DTH2_k127_7991465_0	945713.IALB_0843	2.159e-98	361.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
DTH2_k127_7991465_5	1356852.N008_16190	6.758e-05	55.0	COG1502@1|root,COG4085@1|root,COG1502@2|Bacteria,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	comA	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	HHH_3,PLDc_2
DTH2_k127_7991465_3	1347342.BN863_22780	2.753e-15	89.0	COG3291@1|root,COG3291@2|Bacteria,4PMR5@976|Bacteroidetes,1IJX3@117743|Flavobacteriia	976|Bacteroidetes	N	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
DTH2_k127_7991465_4	1122176.KB903619_gene5403	1.345e-11	77.0	COG1361@1|root,COG1361@2|Bacteria,4NKYJ@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Peptidase_M43,Reprolysin_3,fn3
DTH2_k127_8028585_0	886379.AEWI01000023_gene13	2.042e-232	731.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,2FKYI@200643|Bacteroidia,3XIWI@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH2_k127_8028585_1	1123277.KB893243_gene143	5.988e-30	125.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia	976|Bacteroidetes	E	chorismate mutase	pheB	-	5.4.99.5	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
DTH2_k127_8056227_1	616991.JPOO01000001_gene3645	4.047e-64	223.0	COG3119@1|root,COG3119@2|Bacteria,4NE9D@976|Bacteroidetes,1HY4G@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH2_k127_8056227_0	1121904.ARBP01000005_gene4778	3.497e-119	396.0	COG1082@1|root,COG3291@1|root,COG1082@2|Bacteria,COG3291@2|Bacteria,4P26V@976|Bacteroidetes,47YK8@768503|Cytophagia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH2_k127_8066653_1	925409.KI911562_gene2348	2.395e-97	322.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1IQZT@117747|Sphingobacteriia	976|Bacteroidetes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_8066653_5	1124780.ANNU01000018_gene1642	1.653e-10	69.0	2DG7I@1|root,32U6S@2|Bacteria,4NUFD@976|Bacteroidetes,47XS1@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8066653_4	1237149.C900_00138	7.114e-35	138.0	29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,47Q19@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8066653_2	929556.Solca_1438	5.746e-76	269.0	COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1IRZE@117747|Sphingobacteriia	976|Bacteroidetes	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
DTH2_k127_8066653_0	926549.KI421517_gene3546	0.0	1158.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,47K30@768503|Cytophagia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DTH2_k127_8066653_3	1408433.JHXV01000005_gene2416	4.085e-57	205.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1HWVR@117743|Flavobacteriia,2PAAQ@246874|Cryomorphaceae	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DTH2_k127_8076938_0	443143.GM18_2685	6.488e-59	207.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,431WB@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH2_k127_8076938_1	742766.HMPREF9455_03696	1.485e-34	144.0	COG3547@1|root,COG3547@2|Bacteria,4NHYP@976|Bacteroidetes,2FKYS@200643|Bacteroidia	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
DTH2_k127_8089262_2	391596.PBAL39_02710	3.262e-41	155.0	COG0438@1|root,COG0438@2|Bacteria,4NEJ6@976|Bacteroidetes,1IPXH@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glycos_transf_1
DTH2_k127_8089262_0	700598.Niako_5571	1.714e-84	292.0	COG0438@1|root,COG0438@2|Bacteria,4NMZ6@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH2_k127_8089262_3	1547445.LO80_08515	3.496e-15	88.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH2_k127_8099595_0	1305737.JAFX01000001_gene152	3.118e-59	230.0	COG2972@1|root,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,47QDQ@768503|Cytophagia	976|Bacteroidetes	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,TPR_12,TPR_7,TPR_8
DTH2_k127_8111643_3	926550.CLDAP_22460	4.142e-77	262.0	COG3420@1|root,COG3420@2|Bacteria,2G5T7@200795|Chloroflexi	200795|Chloroflexi	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8111643_2	926569.ANT_26340	7.427e-128	416.0	COG1175@1|root,COG1175@2|Bacteria,2G847@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
DTH2_k127_8111643_1	926569.ANT_26330	7.992e-150	484.0	COG0395@1|root,COG0395@2|Bacteria,2G7N9@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
DTH2_k127_8111643_0	926569.ANT_26320	8.623e-208	655.0	COG5368@1|root,COG5368@2|Bacteria	2|Bacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
DTH2_k127_8111643_4	926569.ANT_26310	1.763e-26	109.0	COG1609@1|root,COG1609@2|Bacteria,2G5ZV@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
DTH2_k127_8123814_20	999419.HMPREF1077_00723	7.43e-14	78.0	28HHN@1|root,2Z7TA@2|Bacteria,4NEXR@976|Bacteroidetes,2FQ6G@200643|Bacteroidia,22Y7B@171551|Porphyromonadaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8123814_16	1501391.LG35_02455	1.369e-46	173.0	2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,2FSVU@200643|Bacteroidia,22VDD@171550|Rikenellaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly	lptE	-	-	-	-	-	-	-	-	-	-	-	LptE
DTH2_k127_8123814_4	927658.AJUM01000034_gene236	4.595e-165	528.0	COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,2FMNM@200643|Bacteroidia,3XIN4@558415|Marinilabiliaceae	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	fhlA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
DTH2_k127_8123814_0	927658.AJUM01000042_gene1732	7.35e-291	914.0	COG0072@1|root,COG0072@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,3XJ3V@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ferredoxin-fold anticodon binding domain	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DTH2_k127_8123814_1	1223410.KN050846_gene167	1.493e-273	860.0	COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia	976|Bacteroidetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DTH2_k127_8123814_13	1408473.JHXO01000001_gene2243	8.287e-61	220.0	28H74@1|root,2Z7JF@2|Bacteria,4NFR0@976|Bacteroidetes,2FQ0B@200643|Bacteroidia	976|Bacteroidetes	S	Gliding motility-associated protein GldN	gldN	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8123814_10	927658.AJUM01000034_gene422	9.033e-84	298.0	28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,2FNU8@200643|Bacteroidia,3XIKX@558415|Marinilabiliaceae	976|Bacteroidetes	S	GldM C-terminal domain	gldM	-	-	-	-	-	-	-	-	-	-	-	GldM_C,GldM_N
DTH2_k127_8123814_15	385682.AFSL01000014_gene2726	3.752e-54	203.0	28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,2FTZD@200643|Bacteroidia,3XJ0V@558415|Marinilabiliaceae	976|Bacteroidetes	S	Gliding motility-associated protein, GldL	gldL	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8123814_3	927658.AJUM01000034_gene424	5.781e-176	562.0	COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,2FPTN@200643|Bacteroidia,3XJTD@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	gldK	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH2_k127_8123814_17	926562.Oweho_2802	4.035e-43	171.0	COG0226@1|root,COG0226@2|Bacteria,4PKGM@976|Bacteroidetes	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8123814_5	485918.Cpin_2050	6.041e-165	529.0	COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,1INRC@117747|Sphingobacteriia	976|Bacteroidetes	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
DTH2_k127_8123814_11	926562.Oweho_2361	3.714e-81	281.0	COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia,2PBQF@246874|Cryomorphaceae	976|Bacteroidetes	M	Peptidase family M23	nlpD_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_8123814_6	1408473.JHXO01000001_gene2274	6.481e-142	484.0	COG1729@1|root,COG1729@2|Bacteria,4PKGA@976|Bacteroidetes,2G3G6@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
DTH2_k127_8123814_18	385682.AFSL01000008_gene2603	6.137e-33	132.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH2_k127_8123814_21	216432.CA2559_03030	4.604e-12	74.0	2DHEX@1|root,2ZZHF@2|Bacteria,4PFIC@976|Bacteroidetes,1I6WF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
DTH2_k127_8123814_9	485917.Phep_4149	1.29e-92	308.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia	976|Bacteroidetes	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
DTH2_k127_8123814_8	1121011.AUCB01000007_gene1270	7.363e-133	428.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia,23FN0@178469|Arenibacter	976|Bacteroidetes	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
DTH2_k127_8123814_12	762903.Pedsa_3849	1.767e-67	237.0	COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,1IS2C@117747|Sphingobacteriia	976|Bacteroidetes	GM	COG4464 Capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
DTH2_k127_8123814_2	694427.Palpr_1296	4.312e-182	574.0	COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia,22W2K@171551|Porphyromonadaceae	976|Bacteroidetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH2_k127_8123814_7	1168034.FH5T_10610	2.383e-139	451.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia	976|Bacteroidetes	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH2_k127_8123814_14	483216.BACEGG_01705	1.149e-55	198.0	COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,2FMXE@200643|Bacteroidia,4AN9V@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH2_k127_8133925_0	1279009.ADICEAN_00552	2.37e-122	398.0	COG0399@1|root,COG0399@2|Bacteria,4NEIU@976|Bacteroidetes,47JAI@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
DTH2_k127_8133925_1	620914.JH621274_gene375	2.17e-51	190.0	COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia,2YHUV@290174|Aquimarina	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DTH2_k127_8143252_11	468059.AUHA01000005_gene2475	4.181e-21	98.0	COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,1IT9C@117747|Sphingobacteriia	976|Bacteroidetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DTH2_k127_8143252_1	929556.Solca_2578	7.609e-183	587.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_8143252_9	1408473.JHXO01000006_gene1137	3.76e-42	160.0	COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,2FTBD@200643|Bacteroidia	976|Bacteroidetes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
DTH2_k127_8143252_10	313628.LNTAR_13667	1.441e-38	147.0	COG1607@1|root,COG1607@2|Bacteria	2|Bacteria	I	acyl-coa hydrolase	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
DTH2_k127_8143252_3	1168034.FH5T_09890	6.312e-102	340.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes,2FRHD@200643|Bacteroidia	976|Bacteroidetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
DTH2_k127_8143252_7	585502.HMPREF0645_0816	2.953e-59	214.0	COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,2FNE2@200643|Bacteroidia	976|Bacteroidetes	J	RNA methyltransferase TrmH	aviRb	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DTH2_k127_8143252_5	1121887.AUDK01000023_gene3473	9.171e-96	323.0	COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia,2NW6Q@237|Flavobacterium	976|Bacteroidetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH2_k127_8143252_12	1150600.ADIARSV_2453	1.836e-13	80.0	2EHJH@1|root,32W49@2|Bacteria,4NTI9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8143252_0	1211813.CAPH01000004_gene1219	6.948e-200	629.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,22UP8@171550|Rikenellaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
DTH2_k127_8143252_6	927658.AJUM01000034_gene147	1.52e-90	301.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,2FMW9@200643|Bacteroidia,3XJC8@558415|Marinilabiliaceae	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
DTH2_k127_8143252_4	880526.KE386488_gene1907	1.741e-97	322.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,2FN5K@200643|Bacteroidia,22U7J@171550|Rikenellaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
DTH2_k127_8143252_8	1189620.AJXL01000030_gene2806	6.043e-58	210.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,1HZG0@117743|Flavobacteriia,2NWMX@237|Flavobacterium	976|Bacteroidetes	C	FMN_bind	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
DTH2_k127_8143252_2	385682.AFSL01000002_gene1850	1.009e-115	378.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia,3XIVE@558415|Marinilabiliaceae	976|Bacteroidetes	C	NQR2, RnfD, RnfE family	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
DTH2_k127_8156035_0	1150600.ADIARSV_2746	8.725e-174	554.0	COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DTH2_k127_8156035_2	945713.IALB_0663	6.775e-126	417.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DTH2_k127_8156035_1	1237149.C900_02753	7.879e-167	537.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DTH2_k127_8156035_3	1168034.FH5T_14375	2.594e-57	220.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K16705	-	-	-	-	ko00000	-	-	-	Wzy_C
DTH2_k127_8156035_4	880526.KE386488_gene1433	4.37e-49	184.0	COG1597@1|root,COG1597@2|Bacteria,4NGPY@976|Bacteroidetes,2FP27@200643|Bacteroidia,22U5U@171550|Rikenellaceae	976|Bacteroidetes	I	lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH2_k127_8166510_1	694427.Palpr_0983	9.692e-09	64.0	28PCM@1|root,2ZC4W@2|Bacteria,4NMCM@976|Bacteroidetes,2FNT0@200643|Bacteroidia,22XXQ@171551|Porphyromonadaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8166510_0	313606.M23134_00108	1.909e-125	410.0	COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,4NHFH@976|Bacteroidetes,47KN5@768503|Cytophagia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
DTH2_k127_819654_9	1492738.FEM21_11300	1.507e-42	157.0	COG4680@1|root,COG4680@2|Bacteria,4NQ54@976|Bacteroidetes,1I2RY@117743|Flavobacteriia,2NWYJ@237|Flavobacterium	976|Bacteroidetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
DTH2_k127_819654_8	402612.FP1227	2.822e-46	169.0	COG5499@1|root,COG5499@2|Bacteria,4NNXF@976|Bacteroidetes,1I2MM@117743|Flavobacteriia,2NWGM@237|Flavobacterium	976|Bacteroidetes	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
DTH2_k127_819654_4	679935.Alfi_1286	5.078e-81	273.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
DTH2_k127_819654_7	1121097.JCM15093_2962	3.639e-60	214.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,2FMZ6@200643|Bacteroidia,4ANA5@815|Bacteroidaceae	976|Bacteroidetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH2_k127_819654_3	886379.AEWI01000210_gene2475	2.884e-161	513.0	COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia,3XIT0@558415|Marinilabiliaceae	976|Bacteroidetes	J	tRNA synthetases class II core domain (F)	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DTH2_k127_819654_11	313594.PI23P_03102	4.861e-05	51.0	2E4I5@1|root,32ZD8@2|Bacteria,4NV9B@976|Bacteroidetes,1I50D@117743|Flavobacteriia,3VWM3@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_819654_0	373903.Hore_23190	5.593e-227	723.0	COG1082@1|root,COG1082@2|Bacteria,1UFEU@1239|Firmicutes,24FG8@186801|Clostridia	186801|Clostridia	G	Glycosyl-hydrolase 97 C-terminal, oligomerisation	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,GH97_C,GH97_N,Glyco_hydro_97,Laminin_G_3
DTH2_k127_819654_6	313606.M23134_05585	6.286e-63	224.0	COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,47K17@768503|Cytophagia	976|Bacteroidetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DTH2_k127_819654_1	468059.AUHA01000002_gene980	6.152e-201	632.0	COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1IPBP@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_819654_10	927658.AJUM01000034_gene225	2.705e-37	141.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,2FTWG@200643|Bacteroidia,3XKCJ@558415|Marinilabiliaceae	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_819654_5	483215.BACFIN_08079	3.673e-73	251.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,2FPNN@200643|Bacteroidia,4ANFT@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
DTH2_k127_819654_2	1286632.P278_21620	2.864e-190	613.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1HWVC@117743|Flavobacteriia	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
DTH2_k127_8216855_0	1408473.JHXO01000007_gene778	2.381e-89	296.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,2FMRS@200643|Bacteroidia	976|Bacteroidetes	E	Tryptophanase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_8216855_1	1168034.FH5T_16830	3.011e-59	208.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,2FS26@200643|Bacteroidia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
DTH2_k127_8216855_4	196164.23493438	1.848e-06	57.0	COG1971@1|root,COG1971@2|Bacteria,2GNBU@201174|Actinobacteria,22N02@1653|Corynebacteriaceae	201174|Actinobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
DTH2_k127_8216855_3	1492737.FEM08_30160	6.041e-52	187.0	COG0720@1|root,COG0720@2|Bacteria,4NM8H@976|Bacteroidetes,1I173@117743|Flavobacteriia,2NST1@237|Flavobacterium	976|Bacteroidetes	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH2_k127_8216855_5	926549.KI421517_gene141	1.802e-05	56.0	2EJJG@1|root,33DAE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8216855_2	216432.CA2559_00625	7.477e-53	199.0	COG3342@1|root,COG3342@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,MAM,Peptidase_M14,fn3
DTH2_k127_8222214_0	886379.AEWI01000037_gene2903	2.02e-237	745.0	COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,2FM7V@200643|Bacteroidia,3XJBP@558415|Marinilabiliaceae	976|Bacteroidetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2
DTH2_k127_8222214_1	762903.Pedsa_0247	1.975e-85	291.0	COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1INNN@117747|Sphingobacteriia	976|Bacteroidetes	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
DTH2_k127_8222214_2	1168034.FH5T_04995	7.948e-27	113.0	2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 9.82	fjo13	-	-	-	-	-	-	-	-	-	-	-	DUF3098
DTH2_k127_8222586_2	402612.FP1959	2.343e-07	56.0	COG1345@1|root,COG1404@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium	976|Bacteroidetes	N	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CUB,fn3
DTH2_k127_8222586_1	1240349.ANGC01000011_gene230	5.743e-11	69.0	2EC8S@1|root,33677@2|Bacteria,2GUT2@201174|Actinobacteria,4G3D7@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8222586_0	1408473.JHXO01000007_gene843	1.912e-159	530.0	COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,2FNGJ@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8235317_4	1168289.AJKI01000006_gene229	3.554e-83	279.0	COG1014@1|root,COG1014@2|Bacteria,4NGWJ@976|Bacteroidetes,2FNG6@200643|Bacteroidia,3XJRX@558415|Marinilabiliaceae	976|Bacteroidetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
DTH2_k127_8235317_2	1191523.MROS_2263	2.765e-117	381.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH2_k127_8235317_1	869213.JCM21142_41688	1.644e-160	512.0	COG0674@1|root,COG0674@2|Bacteria,4NGYK@976|Bacteroidetes	976|Bacteroidetes	C	Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DTH2_k127_8235317_5	575590.HMPREF0156_01581	1.208e-27	113.0	COG1146@1|root,COG1146@2|Bacteria,4NV91@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S binding domain protein	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21,Fer4_4
DTH2_k127_8235317_0	1187851.A33M_3194	6.549e-164	523.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DTH2_k127_8235317_6	1123035.ARLA01000028_gene2122	7.352e-06	58.0	2EK5E@1|root,33DVV@2|Bacteria,4PFHP@976|Bacteroidetes,1I8KT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8235317_3	1232410.KI421412_gene166	3.425e-100	334.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH2_k127_8241849_0	742817.HMPREF9449_00420	4.46e-86	293.0	COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes,2FN1T@200643|Bacteroidia,22W9X@171551|Porphyromonadaceae	976|Bacteroidetes	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DTH2_k127_8241849_1	1168034.FH5T_21035	1.235e-70	243.0	28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,2FKZK@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
DTH2_k127_8241849_2	709991.Odosp_1120	1.154e-20	95.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,2G2Z3@200643|Bacteroidia,22W11@171551|Porphyromonadaceae	976|Bacteroidetes	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
DTH2_k127_8247272_1	6238.CBG08811	0.0005081	44.0	2EW74@1|root,2SY2K@2759|Eukaryota,3AVH6@33154|Opisthokonta,3C40D@33208|Metazoa,3DKPN@33213|Bilateria,40Q8N@6231|Nematoda,1M0JK@119089|Chromadorea,416DZ@6236|Rhabditida	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8247272_0	984262.SGRA_2328	6.272e-34	146.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
DTH2_k127_8248679_4	1408473.JHXO01000001_gene2047	2.972e-98	327.0	COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,2FNUY@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8248679_7	1296416.JACB01000033_gene2218	2.615e-50	188.0	28N2R@1|root,2ZB8J@2|Bacteria,4NTJC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8248679_0	709991.Odosp_1181	1.06e-165	526.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,22W2U@171551|Porphyromonadaceae	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH2_k127_8248679_9	264201.pc1883	3.387e-26	113.0	COG1721@1|root,COG1721@2|Bacteria,2JFXY@204428|Chlamydiae	204428|Chlamydiae	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH2_k127_8248679_5	1121904.ARBP01000007_gene2905	4.952e-77	262.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia	976|Bacteroidetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH2_k127_8248679_6	485917.Phep_1480	2.192e-51	194.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1ISTW@117747|Sphingobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8248679_2	1121904.ARBP01000007_gene2907	1.647e-122	401.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia	976|Bacteroidetes	S	PFAM von Willebrand factor type A	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
DTH2_k127_8248679_3	1168034.FH5T_13670	2.255e-113	376.0	COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,2FN4B@200643|Bacteroidia	976|Bacteroidetes	S	Von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
DTH2_k127_8248679_8	714943.Mucpa_6111	2.992e-30	129.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1ISXE@117747|Sphingobacteriia	976|Bacteroidetes	S	TPR repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
DTH2_k127_8248679_1	657309.BXY_04650	4.096e-127	429.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,4AK7T@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG06393 non supervised orthologous group	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
DTH2_k127_8248679_10	927658.AJUM01000011_gene1321	8.789e-25	107.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,3XIRK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Bacterial SH3 domain	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH2_k127_8278867_1	667014.Thein_0547	1.101e-55	198.0	COG0146@1|root,COG0146@2|Bacteria,2GHSH@200940|Thermodesulfobacteria	2|Bacteria	EQ	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01474	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0266c	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
DTH2_k127_8278867_0	435908.IDSA_01320	2.048e-123	419.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2QEYF@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DTH2_k127_8281149_0	929556.Solca_3388	5.276e-250	781.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1IPC5@117747|Sphingobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
DTH2_k127_8281149_1	398720.MED217_09430	2.727e-25	108.0	COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,1I1ZM@117743|Flavobacteriia,2XJW9@283735|Leeuwenhoekiella	976|Bacteroidetes	K	'Cold-shock' DNA-binding domain	cspG	-	-	-	-	-	-	-	-	-	-	-	CSD
DTH2_k127_8318437_1	929556.Solca_4343	6.296e-86	303.0	COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,1INMH@117747|Sphingobacteriia	976|Bacteroidetes	D	Peptidase, M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH2_k127_8318437_2	1408473.JHXO01000015_gene1897	6.413e-12	79.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH2_k127_8318437_0	1122176.KB903565_gene3321	4.116e-101	357.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia	976|Bacteroidetes	O	Serine protease, subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_8319610_7	1408473.JHXO01000006_gene1269	2.274e-47	178.0	COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,2FPIN@200643|Bacteroidia	976|Bacteroidetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH2_k127_8319610_2	762903.Pedsa_1731	4.564e-155	499.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,1IQ7V@117747|Sphingobacteriia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH2_k127_8319610_5	1408473.JHXO01000006_gene1216	2.077e-115	379.0	COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,2FMK3@200643|Bacteroidia	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DTH2_k127_8319610_4	471854.Dfer_4966	4.353e-116	389.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia	976|Bacteroidetes	CP	COGs COG1668 ABC-type Na efflux pump permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH2_k127_8319610_1	742817.HMPREF9449_02798	1.317e-164	523.0	COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,2FW0G@200643|Bacteroidia,2300H@171551|Porphyromonadaceae	976|Bacteroidetes	O	Deoxyhypusine synthase	dys1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DTH2_k127_8319610_6	313606.M23134_04872	2.014e-113	372.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DTH2_k127_8319610_0	1203611.KB894549_gene2284	1.089e-252	784.0	COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH2_k127_8319610_3	1168034.FH5T_10755	5.408e-125	415.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DTH2_k127_8320484_0	1124780.ANNU01000044_gene542	6.582e-82	286.0	COG5505@1|root,COG5505@2|Bacteria,4NPE1@976|Bacteroidetes,47V2U@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
DTH2_k127_8320484_1	1313421.JHBV01000044_gene2949	1.616e-62	226.0	COG0076@1|root,COG0076@2|Bacteria,4NJ2F@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15,4.1.2.27	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	M00027,M00100	R00261,R00489,R01682,R02464,R02466,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
DTH2_k127_8320484_2	1242864.D187_006755	1.182e-49	185.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria,2YTU4@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
DTH2_k127_8320484_3	1121904.ARBP01000005_gene4626	1.165e-33	134.0	29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes,47T83@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
DTH2_k127_8348126_1	1168034.FH5T_14845	2.349e-36	140.0	COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,2FYHY@200643|Bacteroidia	976|Bacteroidetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DTH2_k127_8348126_0	1479238.JQMZ01000001_gene1346	5.701e-57	205.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter	-	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran
DTH2_k127_8348126_2	344747.PM8797T_02024	1.305e-29	123.0	COG0577@1|root,COG0577@2|Bacteria,2J25K@203682|Planctomycetes	2|Bacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_8368073_2	760192.Halhy_0365	1.003e-43	167.0	COG0241@1|root,COG0241@2|Bacteria,4NR54@976|Bacteroidetes,1IU3D@117747|Sphingobacteriia	976|Bacteroidetes	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,PNK3P
DTH2_k127_8368073_1	1123373.ATXI01000008_gene1561	9.781e-70	243.0	COG1208@1|root,COG1208@2|Bacteria,2GI50@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
DTH2_k127_8368073_0	761193.Runsl_4187	6.649e-73	250.0	COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,47KZ6@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
DTH2_k127_8368073_3	349163.Acry_0794	8.205e-11	72.0	COG3593@1|root,COG4637@1|root,COG3593@2|Bacteria,COG4637@2|Bacteria,1N2CB@1224|Proteobacteria	1224|Proteobacteria	L	ATP-dependent endonuclease of the OLD family	ybjD	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K07459	-	-	-	-	ko00000	-	-	-	DUF2813
DTH2_k127_8372686_0	886379.AEWI01000024_gene384	7.238e-209	654.0	COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,2FMPQ@200643|Bacteroidia,3XIIR@558415|Marinilabiliaceae	976|Bacteroidetes	E	Aminotransferase class-III	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
DTH2_k127_8372686_1	1168289.AJKI01000011_gene500	2.479e-89	298.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,2FSHE@200643|Bacteroidia,3XJKK@558415|Marinilabiliaceae	976|Bacteroidetes	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH2_k127_8372686_2	869213.JCM21142_93813	3.061e-08	54.0	COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,47XZ4@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_8373914_0	1449126.JQKL01000014_gene2985	1.358e-83	283.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
DTH2_k127_8373914_1	1406840.Q763_03470	1.233e-80	278.0	COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia,2NTG9@237|Flavobacterium	976|Bacteroidetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
DTH2_k127_8373914_2	1237149.C900_01112	3.686e-06	51.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
DTH2_k127_8379599_0	1237149.C900_05488	0.0	1179.0	COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia	976|Bacteroidetes	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
DTH2_k127_8380_0	1250232.JQNJ01000001_gene1549	1.493e-133	443.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HTH_18,HisKA,Response_reg,TPR_12,TPR_8
DTH2_k127_8380_1	313606.M23134_07874	6.664e-60	236.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin-like,DUF11,OmpA,SdrD_B,SprB
DTH2_k127_8380_3	1484460.JSWG01000001_gene2233	1.012e-09	70.0	COG0265@1|root,COG1572@1|root,COG0265@2|Bacteria,COG1572@2|Bacteria,4NIM1@976|Bacteroidetes,1I0WD@117743|Flavobacteriia	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Peptidase_M43,Reprolysin_3
DTH2_k127_8380_2	714943.Mucpa_1830	1.328e-10	64.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IPF5@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_8388122_2	1211813.CAPH01000012_gene313	7.044e-62	220.0	2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,2FXHA@200643|Bacteroidia,22USQ@171550|Rikenellaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8388122_3	385682.AFSL01000100_gene40	4.312e-34	141.0	2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,2FNRZ@200643|Bacteroidia,3XJ3D@558415|Marinilabiliaceae	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	porT	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_8388122_1	468059.AUHA01000003_gene1989	2.903e-97	328.0	COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
DTH2_k127_8388122_0	385682.AFSL01000022_gene2107	1.077e-149	486.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,3XJUP@558415|Marinilabiliaceae	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH2_k127_8401846_1	459349.CLOAM0304	5.638e-160	535.0	COG1404@1|root,COG1404@2|Bacteria,2NQX6@2323|unclassified Bacteria	2|Bacteria	O	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
DTH2_k127_8401846_0	468059.AUHA01000002_gene1259	4.224e-240	758.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IPID@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DTH2_k127_8403631_1	1195236.CTER_4827	1.356e-105	349.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DTH2_k127_8403631_3	755732.Fluta_0842	2.251e-66	231.0	COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1HXCB@117743|Flavobacteriia,2PAS5@246874|Cryomorphaceae	976|Bacteroidetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
DTH2_k127_8403631_0	927658.AJUM01000037_gene2095	6.666e-165	531.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,2FNQH@200643|Bacteroidia,3XJ32@558415|Marinilabiliaceae	976|Bacteroidetes	F	Na+ dependent nucleoside transporter C-terminus	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
DTH2_k127_8403631_2	761193.Runsl_1905	3.474e-88	301.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
DTH2_k127_8421496_0	1168289.AJKI01000031_gene963	4.649e-77	263.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,2FNW6@200643|Bacteroidia,3XKSD@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
DTH2_k127_8421496_1	269798.CHU_2632	4.233e-09	69.0	2C5KB@1|root,2ZCDW@2|Bacteria,4NMNY@976|Bacteroidetes,47PDN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_842384_2	1408473.JHXO01000006_gene1037	1.732e-05	52.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
DTH2_k127_842384_1	926562.Oweho_1432	1.161e-12	73.0	COG1826@1|root,COG1826@2|Bacteria,4PFQQ@976|Bacteroidetes,1IGIP@117743|Flavobacteriia,2PBA1@246874|Cryomorphaceae	976|Bacteroidetes	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DTH2_k127_842384_0	1433126.BN938_1421	3.483e-189	604.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,22U2I@171550|Rikenellaceae	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DTH2_k127_8428092_0	1313421.JHBV01000014_gene3820	8.502e-106	371.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_8
DTH2_k127_8444951_1	929556.Solca_4269	1.078e-82	289.0	COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1IPX7@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	porV	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8444951_4	686340.Metal_3843	0.0001211	45.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,1T460@1236|Gammaproteobacteria,1XEF0@135618|Methylococcales	135618|Methylococcales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8444951_0	1218103.CIN01S_09_03670	1.975e-120	395.0	COG2267@1|root,COG2267@2|Bacteria,4PI42@976|Bacteroidetes,1IG42@117743|Flavobacteriia,3ZTHE@59732|Chryseobacterium	976|Bacteroidetes	I	Alpha/beta hydrolase family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hydrolase_4
DTH2_k127_8444951_2	1233950.IW22_17895	3.873e-79	270.0	COG4775@1|root,COG4775@2|Bacteria,4NRT9@976|Bacteroidetes,1I4PV@117743|Flavobacteriia,3ZTEA@59732|Chryseobacterium	976|Bacteroidetes	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8444951_3	700598.Niako_4281	1.136e-26	119.0	COG2885@1|root,COG5295@1|root,COG2885@2|Bacteria,COG5295@2|Bacteria,4NN21@976|Bacteroidetes	976|Bacteroidetes	UW	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH2_k127_8454223_3	641143.HMPREF9331_00100	1.87e-54	197.0	COG0815@1|root,COG0815@2|Bacteria,4NG4X@976|Bacteroidetes,1HY5K@117743|Flavobacteriia,1EQX8@1016|Capnocytophaga	976|Bacteroidetes	M	apolipoprotein N-acyltransferase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH2_k127_8454223_1	694427.Palpr_2794	4.798e-165	528.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,2FM9T@200643|Bacteroidia,22W7M@171551|Porphyromonadaceae	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DTH2_k127_8454223_0	694427.Palpr_2106	2.454e-174	551.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,2FMAT@200643|Bacteroidia,22VZJ@171551|Porphyromonadaceae	976|Bacteroidetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DTH2_k127_8454223_2	1168289.AJKI01000022_gene1907	1.31e-58	212.0	COG0810@1|root,COG2304@1|root,COG0810@2|Bacteria,COG2304@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,3XJWP@558415|Marinilabiliaceae	976|Bacteroidetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DTH2_k127_8458557_3	1047013.AQSP01000115_gene352	1.125e-109	366.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8458557_1	1121451.DESAM_21610	1.447e-150	488.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
DTH2_k127_8458557_4	272123.Anacy_1669	9.125e-38	145.0	2DNS7@1|root,32YWC@2|Bacteria,1G8QD@1117|Cyanobacteria,1HP4W@1161|Nostocales	1117|Cyanobacteria	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH2_k127_8458557_0	1168034.FH5T_20545	0.0	1050.0	COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,2FX28@200643|Bacteroidia	976|Bacteroidetes	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH2_k127_8458557_2	1191523.MROS_0242	3.819e-113	379.0	292UM@1|root,2ZQC9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_846258_5	1121859.KB890756_gene1553	9.228e-14	78.0	2DM4T@1|root,31QCU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_846258_3	1125701.HMPREF1221_02386	1.461e-18	95.0	COG3595@1|root,COG3595@2|Bacteria,2J7E0@203691|Spirochaetes	203691|Spirochaetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
DTH2_k127_846258_2	1380384.JADN01000009_gene207	9.082e-22	108.0	COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,1HYD6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_846258_1	313606.M23134_04372	2.358e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,47P7T@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_846258_0	869213.JCM21142_83238	7.114e-236	736.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,47KN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH2_k127_8482749_2	755732.Fluta_1488	9.439e-90	304.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8482749_1	112098.XP_008605974.1	2.365e-119	400.0	COG0469@1|root,KOG2323@2759|Eukaryota	2759|Eukaryota	G	pyruvate kinase activity	-	GO:0000003,GO:0000287,GO:0003006,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006629,GO:0006631,GO:0006633,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009791,GO:0009987,GO:0010035,GO:0010038,GO:0010154,GO:0010431,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0021700,GO:0022414,GO:0030955,GO:0031420,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046686,GO:0046700,GO:0046872,GO:0046939,GO:0048316,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0061458,GO:0071695,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
DTH2_k127_8482749_4	743722.Sph21_0279	1.491e-18	86.0	COG2608@1|root,COG2608@2|Bacteria,4NURN@976|Bacteroidetes,1IUGG@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
DTH2_k127_8482749_0	1124780.ANNU01000033_gene1303	3.124e-261	824.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,47MMN@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DTH2_k127_8482749_3	1121912.AUHD01000008_gene46	5.917e-48	174.0	COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,1I4WB@117743|Flavobacteriia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH2_k127_8491219_5	471854.Dfer_2575	6.92e-53	189.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,47JZJ@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DTH2_k127_8491219_2	929556.Solca_3859	7.098e-138	446.0	COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,1IQ84@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH2_k127_8491219_0	1107311.Q767_08085	5.433e-247	775.0	COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia,2NT2W@237|Flavobacterium	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DTH2_k127_8491219_4	1382359.JIAL01000001_gene1135	8.272e-63	222.0	COG2227@1|root,COG2227@2|Bacteria,3Y9AQ@57723|Acidobacteria	57723|Acidobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8491219_3	1122176.KB903555_gene3755	5.607e-129	423.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1INVH@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DTH2_k127_8491219_1	991.IW20_11430	3.645e-193	609.0	COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia,2NSBD@237|Flavobacterium	976|Bacteroidetes	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH2_k127_8491219_6	1121405.dsmv_3000	8.091e-51	194.0	COG0674@1|root,COG0674@2|Bacteria,1R4K0@1224|Proteobacteria,42NQJ@68525|delta/epsilon subdivisions,2WJ0K@28221|Deltaproteobacteria,2MIND@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
DTH2_k127_8493016_0	927658.AJUM01000041_gene1782	2.652e-145	468.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,2FM6E@200643|Bacteroidia,3XJEW@558415|Marinilabiliaceae	976|Bacteroidetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_8493016_1	1349822.NSB1T_07945	7.092e-84	282.0	COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,2FM1C@200643|Bacteroidia,22WED@171551|Porphyromonadaceae	976|Bacteroidetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
DTH2_k127_8493016_3	1408433.JHXV01000001_gene946	1.412e-32	137.0	COG2849@1|root,COG2849@2|Bacteria,4NP2Z@976|Bacteroidetes,1I22V@117743|Flavobacteriia,2PB39@246874|Cryomorphaceae	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_8493016_2	1408473.JHXO01000011_gene3002	3.906e-58	209.0	COG0546@1|root,COG0546@2|Bacteria,4NRB4@976|Bacteroidetes,2FTCK@200643|Bacteroidia	976|Bacteroidetes	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH2_k127_8493016_4	641524.ADICYQ_1811	1.179e-16	81.0	COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia	976|Bacteroidetes	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
DTH2_k127_8502926_0	945713.IALB_0843	5.073e-48	184.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
DTH2_k127_8511064_0	1237149.C900_01418	1.789e-266	837.0	COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,47KKH@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH2_k127_8511064_2	158189.SpiBuddy_0570	1.306e-64	233.0	COG0240@1|root,COG0240@2|Bacteria,2J68Z@203691|Spirochaetes	203691|Spirochaetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
DTH2_k127_8511064_3	1121373.KB903632_gene430	3.576e-41	175.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NRYE@976|Bacteroidetes,47KIU@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM gliding motility-associated C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_8511064_1	1122176.KB903598_gene4693	5.855e-86	315.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PHZG@976|Bacteroidetes,1IW5N@117747|Sphingobacteriia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Peptidase_M43
DTH2_k127_8517072_2	385682.AFSL01000082_gene1208	7.738e-30	125.0	COG0589@1|root,COG0589@2|Bacteria,4PIZC@976|Bacteroidetes,2G22C@200643|Bacteroidia,3XJ4E@558415|Marinilabiliaceae	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_8517072_3	1408473.JHXO01000001_gene2450	6.133e-20	96.0	2EJD3@1|root,33D44@2|Bacteria,4NYG1@976|Bacteroidetes,2FVDP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_8517072_1	869213.JCM21142_31209	1.239e-40	161.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH2_k127_8517072_0	880073.Calab_3365	1.383e-170	540.0	COG0191@1|root,COG0191@2|Bacteria,2NQQQ@2323|unclassified Bacteria	2|Bacteria	G	Fructose tagatose bisphosphate aldolase	fbaA	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
DTH2_k127_8524204_7	1168289.AJKI01000026_gene1418	5.348e-77	263.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4PMXZ@976|Bacteroidetes,2G0K9@200643|Bacteroidia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH2_k127_8524204_11	1121904.ARBP01000006_gene4028	4.198e-52	188.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
DTH2_k127_8524204_0	1408473.JHXO01000007_gene810	2.432e-251	782.0	COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,2FQ86@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH2_k127_8524204_10	1408473.JHXO01000007_gene809	3.259e-69	245.0	COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FXJ6@200643|Bacteroidia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH2_k127_8524204_5	646529.Desaci_1148	2.188e-109	364.0	COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,25AZV@186801|Clostridia	186801|Clostridia	S	oxidoreductase	-	-	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH2_k127_8524204_8	1121887.AUDK01000014_gene2405	6.848e-77	273.0	COG4271@1|root,COG4271@2|Bacteria,4NKKU@976|Bacteroidetes,1I0UP@117743|Flavobacteriia	976|Bacteroidetes	K	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like
DTH2_k127_8524204_1	1408473.JHXO01000001_gene2487	1.253e-223	703.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FQ0Q@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH2_k127_8524204_6	655815.ZPR_4658	3.008e-104	343.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1IKAY@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH2_k127_8524204_3	886379.AEWI01000018_gene1291	7.49e-165	532.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,4NKA5@976|Bacteroidetes,2FRBU@200643|Bacteroidia,3XJT2@558415|Marinilabiliaceae	976|Bacteroidetes	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
DTH2_k127_8524204_2	983544.Lacal_0944	3.739e-184	610.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NFZQ@976|Bacteroidetes,1HWXQ@117743|Flavobacteriia	976|Bacteroidetes	L	COG3893 Inactivated superfamily I helicase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
DTH2_k127_8524204_9	1408473.JHXO01000005_gene1759	3.153e-70	245.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,2FNEE@200643|Bacteroidia	976|Bacteroidetes	JM	Nucleotidyl transferase	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
DTH2_k127_8524204_4	869213.JCM21142_83097	1.356e-145	475.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,4NIT0@976|Bacteroidetes,47U9Z@768503|Cytophagia	976|Bacteroidetes	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	APH,ATP_bind_2
DTH2_k127_853026_1	1341155.FSS13T_08770	1.456e-21	97.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2NV6A@237|Flavobacterium	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
DTH2_k127_853026_0	1168034.FH5T_12950	4.11e-60	233.0	COG2972@1|root,COG2972@2|Bacteria,4NGA0@976|Bacteroidetes	976|Bacteroidetes	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
DTH2_k127_853026_2	1121897.AUGO01000001_gene1300	1.799e-18	85.0	COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,1HYJ3@117743|Flavobacteriia,2NV1Z@237|Flavobacterium	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
DTH2_k127_8534590_1	1168034.FH5T_12590	9.801e-59	215.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,2FR07@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
DTH2_k127_8534590_4	1089547.KB913013_gene2672	1.894e-16	81.0	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
DTH2_k127_8534590_3	880071.Fleli_3493	9.116e-23	101.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,47RYW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8534590_0	468059.AUHA01000003_gene1452	9.501e-139	448.0	COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1IQ1P@117747|Sphingobacteriia	976|Bacteroidetes	C	Thioredoxin reductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH2_k127_8534590_2	1121097.JCM15093_1900	2.998e-33	134.0	COG0053@1|root,COG0053@2|Bacteria,4NFBB@976|Bacteroidetes,2G36X@200643|Bacteroidia,4AWAU@815|Bacteroidaceae	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH2_k127_8550080_1	1536769.P40081_36300	2.12e-73	252.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,4HB4B@91061|Bacilli,26RQK@186822|Paenibacillaceae	91061|Bacilli	S	Putative esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH2_k127_8550080_0	160799.PBOR_34990	2.457e-154	496.0	COG0151@1|root,COG0151@2|Bacteria,1TRIN@1239|Firmicutes,4ISAR@91061|Bacilli,26V8J@186822|Paenibacillaceae	91061|Bacilli	F	Carboxylate--amine ligase	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
DTH2_k127_8559843_1	1168034.FH5T_06875	9.683e-138	463.0	COG3209@1|root,COG3291@1|root,COG4935@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,2G2RT@200643|Bacteroidia	976|Bacteroidetes	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,HYR,Laminin_G_3,SprB,TSP_3
DTH2_k127_8559843_5	1168289.AJKI01000031_gene1057	0.0001036	52.0	COG3209@1|root,COG3291@1|root,COG3405@1|root,COG4932@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria,COG4932@2|Bacteria,4NDZC@976|Bacteroidetes,2G0D0@200643|Bacteroidia,3XIPK@558415|Marinilabiliaceae	976|Bacteroidetes	GM	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
DTH2_k127_8559843_0	1121889.AUDM01000028_gene491	9.583e-150	519.0	COG2911@1|root,COG3291@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CUB,Cleaved_Adhesin,MAM,fn3
DTH2_k127_8559843_4	700598.Niako_2982	5.094e-24	120.0	COG3291@1|root,COG3291@2|Bacteria,4P4YJ@976|Bacteroidetes	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
DTH2_k127_8559843_2	926562.Oweho_1769	3.831e-66	238.0	COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,1HZRC@117743|Flavobacteriia,2PANF@246874|Cryomorphaceae	976|Bacteroidetes	P	Type IX secretion system membrane protein PorP/SprF	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8568564_0	1168034.FH5T_05825	9.847e-159	514.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH2_k127_8568564_1	1121012.AUKX01000033_gene598	9.208e-41	157.0	COG2755@1|root,COG2755@2|Bacteria,4NPB3@976|Bacteroidetes,1I1BB@117743|Flavobacteriia,23I1W@178469|Arenibacter	976|Bacteroidetes	E	OSK domain	estA	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH2_k127_8571419_2	1453500.AT05_11130	2.284e-77	265.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1HXMK@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH2_k127_8571419_4	1121904.ARBP01000004_gene977	4.121e-43	164.0	COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,47QAA@768503|Cytophagia	976|Bacteroidetes	S	PFAM SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
DTH2_k127_8571419_1	504472.Slin_5196	3.995e-141	456.0	COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,47KJZ@768503|Cytophagia	976|Bacteroidetes	M	TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH2_k127_8571419_0	1124780.ANNU01000045_gene2306	2.294e-265	836.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,47MF3@768503|Cytophagia	976|Bacteroidetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH2_k127_8571419_3	595460.RRSWK_05371	1.247e-52	189.0	COG2954@1|root,COG2954@2|Bacteria	2|Bacteria	S	triphosphatase activity	cyaA	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
DTH2_k127_8571419_5	59374.Fisuc_2472	3.786e-26	115.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
DTH2_k127_8580638_2	391603.FBALC1_12282	1.697e-10	65.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,1HWTD@117743|Flavobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	OstA,OstA_2
DTH2_k127_8580638_1	1121129.KB903367_gene2903	6.797e-74	259.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,2FPK9@200643|Bacteroidia,22X9M@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Virulence factor Mce family protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH2_k127_8580638_0	984262.SGRA_2055	1.906e-76	266.0	COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,1ISH9@117747|Sphingobacteriia	976|Bacteroidetes	M	Cell wall hydrolase autolysin	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH2_k127_8589512_0	1168034.FH5T_08925	7.204e-110	367.0	COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,2FNAB@200643|Bacteroidia	976|Bacteroidetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DTH2_k127_8589512_2	1168034.FH5T_08920	1.317e-22	99.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DTH2_k127_8589512_1	926562.Oweho_2371	1.58e-48	178.0	COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1I239@117743|Flavobacteriia,2PB2M@246874|Cryomorphaceae	976|Bacteroidetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
DTH2_k127_8589512_3	1121930.AQXG01000002_gene1903	3.335e-18	91.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DTH2_k127_8592266_2	1349822.NSB1T_06725	1.517e-20	94.0	28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,2FM8F@200643|Bacteroidia,22XQ4@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4290
DTH2_k127_8592266_0	435591.BDI_0477	1.551e-208	655.0	COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,2FNYN@200643|Bacteroidia,22WZU@171551|Porphyromonadaceae	976|Bacteroidetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
DTH2_k127_8592266_1	869213.JCM21142_104547	1.152e-53	205.0	COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
DTH2_k127_8594528_3	1496688.ER33_02795	2.818e-43	160.0	COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,22TKN@167375|Cyanobium	1117|Cyanobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
DTH2_k127_8594528_0	1121904.ARBP01000006_gene4086	1.194e-120	408.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,47MU1@768503|Cytophagia	976|Bacteroidetes	T	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
DTH2_k127_8594528_2	1122973.KB904203_gene1837	4.591e-63	224.0	COG1376@1|root,COG1376@2|Bacteria,4NNX7@976|Bacteroidetes,2FM99@200643|Bacteroidia,22XQ2@171551|Porphyromonadaceae	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
DTH2_k127_8594528_1	746697.Aeqsu_1954	7.736e-64	245.0	COG4886@1|root,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Recep_L_domain
DTH2_k127_8594528_5	1229487.AMYW01000043_gene3685	0.0001066	55.0	COG4886@1|root,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia,2NT0J@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_8594528_4	761193.Runsl_2120	7.187e-31	125.0	COG0115@1|root,COG0115@2|Bacteria,4PJ29@976|Bacteroidetes,47M6P@768503|Cytophagia	976|Bacteroidetes	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DTH2_k127_8596923_1	869213.JCM21142_103	8.738e-121	396.0	COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes	976|Bacteroidetes	I	fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH2_k127_8596923_0	1121904.ARBP01000026_gene619	2.902e-220	695.0	COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,47KSE@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DTH2_k127_8596923_2	1313421.JHBV01000005_gene4574	1.451e-08	57.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1ISPK@117747|Sphingobacteriia	976|Bacteroidetes	T	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_8613584_4	59374.Fisuc_2472	2.352e-30	129.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Fib_succ_major
DTH2_k127_8613584_3	1203611.KB894544_gene1972	4.997e-37	151.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,4NGHH@976|Bacteroidetes,2FMHT@200643|Bacteroidia,22U0W@171550|Rikenellaceae	976|Bacteroidetes	M	Lysin motif	mepM_1	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
DTH2_k127_8613584_6	485918.Cpin_1422	5.461e-19	97.0	2C2QD@1|root,33JG0@2|Bacteria,4PQ05@976|Bacteroidetes,1IZHI@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8613584_2	880073.Calab_3408	7.039e-58	205.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
DTH2_k127_8613584_5	1122605.KB893625_gene2027	1.298e-25	114.0	2EU2T@1|root,33MJR@2|Bacteria,4NZIZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8613584_7	991905.SL003B_1897	1.594e-08	62.0	COG3216@1|root,COG3216@2|Bacteria,1QA1I@1224|Proteobacteria,2TS9W@28211|Alphaproteobacteria,4BQSU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
DTH2_k127_8613584_1	509635.N824_19065	3.169e-68	241.0	COG0300@1|root,COG0300@2|Bacteria,4NJUU@976|Bacteroidetes,1IRGH@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
DTH2_k127_8613584_0	485917.Phep_2441	3.407e-75	264.0	COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,1IQN9@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM NAD dependent epimerase dehydratase family	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DTH2_k127_8627258_0	1408473.JHXO01000007_gene849	2.707e-190	599.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,2FQB7@200643|Bacteroidia	976|Bacteroidetes	C	dehydrogenase E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_8627258_1	1168034.FH5T_17700	1.136e-137	448.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FN98@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_8662582_0	385682.AFSL01000002_gene1867	9.045e-73	250.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia,3XJVK@558415|Marinilabiliaceae	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH2_k127_8662582_2	886379.AEWI01000046_gene3109	5.83e-55	196.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia,3XK37@558415|Marinilabiliaceae	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
DTH2_k127_8662582_1	1121129.KB903359_gene1659	3.926e-62	223.0	COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,2FN0H@200643|Bacteroidia,22X9Q@171551|Porphyromonadaceae	976|Bacteroidetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
DTH2_k127_8662582_3	1124780.ANNU01000003_gene1437	9.155e-39	157.0	COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia	976|Bacteroidetes	C	PFAM Class III cytochrome C family	actA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrom_CIII,Cytochrome_C7
DTH2_k127_8669568_4	1122221.JHVI01000017_gene2062	4.855e-36	141.0	COG2391@1|root,COG2391@2|Bacteria,1WK5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_8669568_3	421531.IX38_21505	3.019e-40	154.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1I29E@117743|Flavobacteriia,3ZPYP@59732|Chryseobacterium	976|Bacteroidetes	S	Transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
DTH2_k127_8669568_0	909663.KI867150_gene2211	1.782e-103	352.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MQ95@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
DTH2_k127_8669568_2	439235.Dalk_0307	6.257e-69	240.0	COG0045@1|root,COG0045@2|Bacteria,1REBV@1224|Proteobacteria,42S1F@68525|delta/epsilon subdivisions,2WNW1@28221|Deltaproteobacteria,2MJUN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
DTH2_k127_8669568_1	161156.JQKW01000001_gene1433	1.879e-79	278.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GH97@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DTH2_k127_8673522_3	402612.FP0740	2.771e-08	59.0	2E6Q3@1|root,331AC@2|Bacteria,4NUP2@976|Bacteroidetes,1I4Z6@117743|Flavobacteriia,2NWBJ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5362
DTH2_k127_8673522_0	385682.AFSL01000006_gene2384	0.0	1194.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia,3XJR0@558415|Marinilabiliaceae	976|Bacteroidetes	GKT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	-	-	-	-	-	-	-	-	-	-	PPDK_N,Response_reg
DTH2_k127_8673522_2	906888.JCM19314_2643	2.259e-18	86.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH2_k127_8673522_1	1178825.ALIH01000019_gene1230	4.281e-69	239.0	COG0664@1|root,COG0664@2|Bacteria,4NNT7@976|Bacteroidetes,1I1XI@117743|Flavobacteriia	976|Bacteroidetes	K	CRP FNR family transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
DTH2_k127_8704214_1	459349.CLOAM1811	8.318e-33	138.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K06987,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,DUF4859,FlgD_ig,Peptidase_M14
DTH2_k127_8704214_2	269797.Mbar_A3144	1.139e-11	77.0	COG3391@1|root,arCOG02527@1|root,arCOG03991@1|root,arCOG02527@2157|Archaea,arCOG02562@2157|Archaea,arCOG03991@2157|Archaea	2157|Archaea	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Lactonase,NosD,PKD,PQQ_3
DTH2_k127_8704214_5	1250005.PHEL85_2340	2.221e-06	60.0	COG3266@1|root,COG3266@2|Bacteria,4NH1U@976|Bacteroidetes,1HX0D@117743|Flavobacteriia,3VWRQ@52959|Polaribacter	976|Bacteroidetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_8704214_0	313606.M23134_01410	9.894e-45	170.0	COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47PTY@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_8704214_3	643867.Ftrac_1411	7.334e-10	72.0	COG4886@1|root,COG4886@2|Bacteria,4NUAH@976|Bacteroidetes,47RID@768503|Cytophagia	976|Bacteroidetes	S	Leucine Rich Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_8704214_4	521011.Mpal_1961	2.238e-09	70.0	COG3291@1|root,arCOG03991@1|root,arCOG02510@2157|Archaea,arCOG03991@2157|Archaea,2Y7Y5@28890|Euryarchaeota	2157|Archaea	S	SMART cellulose binding type IV	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,NosD,PKD,PQQ_3
DTH2_k127_8704214_6	398720.MED217_18085	1.07e-05	55.0	COG3637@1|root,COG3637@2|Bacteria,4PKUA@976|Bacteroidetes,1IJF5@117743|Flavobacteriia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_8721347_7	929556.Solca_2064	1.102e-12	68.0	COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia	976|Bacteroidetes	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH2_k127_8721347_6	385682.AFSL01000074_gene1279	3.874e-32	137.0	2D6WA@1|root,32TMZ@2|Bacteria,4NU16@976|Bacteroidetes,2FYYU@200643|Bacteroidia,3XKM2@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH2_k127_8721347_0	1408473.JHXO01000016_gene1934	5.883e-164	530.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FR8P@200643|Bacteroidia	976|Bacteroidetes	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
DTH2_k127_8721347_3	1408473.JHXO01000016_gene1933	4.678e-98	326.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,2FT12@200643|Bacteroidia	976|Bacteroidetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH2_k127_8721347_1	1408473.JHXO01000016_gene1932	7.094e-135	436.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,2FMR9@200643|Bacteroidia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_8721347_5	1042376.AFPK01000028_gene2043	1.821e-45	171.0	COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia,406JJ@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
DTH2_k127_8721347_4	865938.Weevi_1242	8.685e-54	193.0	COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1I191@117743|Flavobacteriia	976|Bacteroidetes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DTH2_k127_8721347_2	1408473.JHXO01000006_gene1174	9.484e-110	364.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,2FNEZ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8723722_2	1408433.JHXV01000022_gene3142	3.624e-81	284.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes,1I891@117743|Flavobacteriia,2PA81@246874|Cryomorphaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8723722_1	760192.Halhy_4035	7.26e-90	308.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes,1IYUI@117747|Sphingobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
DTH2_k127_8723722_3	1004149.AFOE01000002_gene2255	2.91e-61	214.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia	976|Bacteroidetes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DTH2_k127_8723722_4	1408473.JHXO01000010_gene3573	2.657e-49	179.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,2FSRY@200643|Bacteroidia	976|Bacteroidetes	FG	Histidine triad domain protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DTH2_k127_8723722_0	742725.HMPREF9450_01234	1.004e-259	813.0	COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,2FM3Y@200643|Bacteroidia,22USY@171550|Rikenellaceae	976|Bacteroidetes	F	Class II glutamine amidotransferase	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH2_k127_8733281_3	1408433.JHXV01000009_gene1251	5.459e-52	202.0	COG0642@1|root,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,1HXAX@117743|Flavobacteriia,2PBD9@246874|Cryomorphaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
DTH2_k127_8733281_1	1304880.JAGB01000001_gene547	3.97e-106	359.0	COG0454@1|root,COG0456@2|Bacteria,1TT30@1239|Firmicutes,24DE0@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_8733281_4	1223410.KN050846_gene688	4.989e-13	81.0	COG4932@1|root,COG4932@2|Bacteria,4NXB2@976|Bacteroidetes	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8733281_2	745718.JADT01000005_gene6	6.721e-59	218.0	COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,1HYY0@117743|Flavobacteriia	976|Bacteroidetes	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
DTH2_k127_8733281_0	1454007.JAUG01000054_gene2593	7.554e-213	680.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_87385_0	452637.Oter_3730	1.726e-52	195.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Esterase_phd
DTH2_k127_87385_1	153721.MYP_1592	6.082e-15	74.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH2_k127_8740744_1	1406840.Q763_12010	5.194e-80	272.0	COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,1HXCG@117743|Flavobacteriia,2NSPJ@237|Flavobacterium	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
DTH2_k127_8740744_0	1408473.JHXO01000010_gene3744	3.505e-168	533.0	COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,2FMFT@200643|Bacteroidia	976|Bacteroidetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DTH2_k127_8740744_2	385682.AFSL01000055_gene388	3.026e-09	61.0	COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,2FTGI@200643|Bacteroidia,3XJII@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DTH2_k127_8753276_3	445970.ALIPUT_00914	4.151e-48	173.0	COG2048@1|root,COG2048@2|Bacteria,4NHHH@976|Bacteroidetes,2FM47@200643|Bacteroidia,22UYS@171550|Rikenellaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
DTH2_k127_8753276_1	742817.HMPREF9449_00255	3.291e-96	327.0	COG1148@1|root,COG2072@1|root,COG1148@2|Bacteria,COG2072@2|Bacteria,4NI95@976|Bacteroidetes,2FRRV@200643|Bacteroidia,22Z3B@171551|Porphyromonadaceae	976|Bacteroidetes	CP	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,HI0933_like,Pyr_redox_2
DTH2_k127_8753276_4	1033732.CAHI01000003_gene2413	5.109e-26	110.0	COG1150@1|root,COG1150@2|Bacteria,4NTRW@976|Bacteroidetes,2FTYK@200643|Bacteroidia,22VH4@171550|Rikenellaceae	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_7,Fer4_9
DTH2_k127_8753276_0	709991.Odosp_0419	3.994e-184	593.0	COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,2FRID@200643|Bacteroidia,22ZH9@171551|Porphyromonadaceae	976|Bacteroidetes	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
DTH2_k127_8753276_2	485918.Cpin_3102	3.931e-77	263.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_8753276_5	1123234.AUKI01000019_gene411	0.0002874	51.0	COG0457@1|root,COG0642@1|root,COG0784@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
DTH2_k127_8756446_0	446470.Snas_0537	9.034e-124	414.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
DTH2_k127_8756446_1	537011.PREVCOP_05982	0.0002425	44.0	COG3086@1|root,COG3086@2|Bacteria,4NV0R@976|Bacteroidetes,2FS4Y@200643|Bacteroidia	976|Bacteroidetes	T	Positive regulator of sigma(E), RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
DTH2_k127_8766001_0	1408473.JHXO01000001_gene2295	1.012e-140	467.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
DTH2_k127_8766001_1	1168034.FH5T_04010	8.766e-17	82.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,2FNA8@200643|Bacteroidia	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DTH2_k127_8766206_3	1336803.PHEL49_2274	0.0003129	47.0	COG2273@1|root,COG2273@2|Bacteria,4NHWA@976|Bacteroidetes,1HX44@117743|Flavobacteriia,3VVG3@52959|Polaribacter	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH2_k127_8766206_2	592015.HMPREF1705_00437	4.92e-21	93.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8766206_1	111780.Sta7437_3417	1.576e-23	100.0	COG1724@1|root,COG1724@2|Bacteria,1G9Z7@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DTH2_k127_8766206_0	203275.BFO_0431	4.01e-66	242.0	COG1305@1|root,COG1305@2|Bacteria,4NIJF@976|Bacteroidetes,2FQJU@200643|Bacteroidia,22XJ6@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
DTH2_k127_8775828_3	1191523.MROS_0500	8.727e-23	99.0	COG1308@1|root,COG1308@2|Bacteria	2|Bacteria	K	protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
DTH2_k127_8775828_1	1150600.ADIARSV_2427	6.305e-69	241.0	COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1IPMJ@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Shikimate dehydrogenase substrate binding	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
DTH2_k127_8775828_0	714943.Mucpa_3996	1.473e-109	371.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
DTH2_k127_8775828_2	1033732.CAHI01000015_gene382	1.564e-28	117.0	COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,2FM6E@200643|Bacteroidia,22TZF@171550|Rikenellaceae	976|Bacteroidetes	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH2_k127_8777127_2	694427.Palpr_0475	2.665e-108	357.0	COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,2FQKK@200643|Bacteroidia,22WMH@171551|Porphyromonadaceae	976|Bacteroidetes	S	AbgT putative transporter family	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
DTH2_k127_8777127_0	880073.Calab_2508	7.247e-314	984.0	COG2866@1|root,COG2866@2|Bacteria,2NQNH@2323|unclassified Bacteria	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
DTH2_k127_8777127_1	945713.IALB_1874	7.649e-155	495.0	COG4690@1|root,COG4690@2|Bacteria	2|Bacteria	E	dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
DTH2_k127_8781525_0	929556.Solca_2296	6.075e-106	350.0	COG4870@1|root,COG4870@2|Bacteria,4NQK4@976|Bacteroidetes,1J06F@117747|Sphingobacteriia	976|Bacteroidetes	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
DTH2_k127_8781525_1	886377.Murru_0108	2.221e-73	263.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase M1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH2_k127_8794126_0	926562.Oweho_1022	1.743e-61	237.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2PBDK@246874|Cryomorphaceae	976|Bacteroidetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8794126_2	1239962.C943_01339	1.322e-09	70.0	COG3866@1|root,COG4254@1|root,COG5492@1|root,COG3866@2|Bacteria,COG4254@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	pel3	-	-	-	-	-	-	-	-	-	-	-	FecR,Pectinesterase
DTH2_k127_8794126_1	1162668.LFE_0393	1.039e-24	117.0	COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae	40117|Nitrospirae	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_8820547_2	1408473.JHXO01000010_gene3615	7.395e-97	323.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,4PNHR@976|Bacteroidetes	976|Bacteroidetes	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoaC
DTH2_k127_8820547_0	880526.KE386488_gene1201	4.663e-107	372.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia,22U3G@171550|Rikenellaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
DTH2_k127_8820547_4	573413.Spirs_1629	1.14e-52	189.0	COG0315@1|root,COG0315@2|Bacteria,2J81J@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
DTH2_k127_8820547_3	1123274.KB899413_gene789	4.908e-83	283.0	COG2896@1|root,COG2896@2|Bacteria,2J7IB@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
DTH2_k127_8820547_1	1408473.JHXO01000010_gene3618	1.817e-102	346.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DTH2_k127_8820547_5	1279009.ADICEAN_01361	4.047e-21	99.0	COG3386@1|root,COG3386@2|Bacteria,4NYVH@976|Bacteroidetes,47XBY@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_883460_0	1237149.C900_05913	1.056e-53	203.0	COG4677@1|root,COG4704@1|root,COG5184@1|root,COG5492@1|root,COG4677@2|Bacteria,COG4704@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PN9Q@976|Bacteroidetes,47Y9H@768503|Cytophagia	976|Bacteroidetes	DZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
DTH2_k127_883460_1	521045.Kole_0405	5.066e-36	143.0	COG1063@1|root,COG1063@2|Bacteria,2GCH6@200918|Thermotogae	200918|Thermotogae	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
DTH2_k127_8836086_0	313606.M23134_00063	3.894e-76	260.0	COG3341@1|root,COG3341@2|Bacteria,4PKFF@976|Bacteroidetes,47Y0T@768503|Cytophagia	976|Bacteroidetes	L	Caulimovirus viroplasmin	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
DTH2_k127_8836086_2	1250006.JHZZ01000001_gene864	1.647e-06	56.0	2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,1I2XD@117743|Flavobacteriia,3VWJG@52959|Polaribacter	976|Bacteroidetes	S	GldH lipoprotein	gldH	GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	GldH_lipo
DTH2_k127_8836086_1	1237149.C900_01189	7.617e-37	141.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
DTH2_k127_8862153_9	767817.Desgi_0130	8.842e-37	143.0	2FDZN@1|root,345ZW@2|Bacteria	2|Bacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
DTH2_k127_8862153_10	926560.KE387023_gene3023	3.707e-23	100.0	COG1476@1|root,COG1476@2|Bacteria,1WN5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DTH2_k127_8862153_6	1191523.MROS_1658	1.298e-48	188.0	28JI8@1|root,2Z9BM@2|Bacteria	2|Bacteria	S	s1 p1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease,Zn_dep_PLPC
DTH2_k127_8862153_11	517418.Ctha_1582	4.088e-12	78.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,F5_F8_type_C,SLH
DTH2_k127_8862153_5	1453500.AT05_07385	9.509e-82	281.0	COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia	976|Bacteroidetes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH2_k127_8862153_3	760192.Halhy_2122	3.436e-83	284.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,4NEUZ@976|Bacteroidetes	2|Bacteria	KLT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14,Pkinase,Trypsin_2
DTH2_k127_8862153_0	746697.Aeqsu_0488	2.769e-190	607.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH2_k127_8862153_7	709991.Odosp_0201	9.595e-48	179.0	COG1309@1|root,COG1309@2|Bacteria,4P20N@976|Bacteroidetes,2FXF4@200643|Bacteroidia,22ZS9@171551|Porphyromonadaceae	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8862153_8	926562.Oweho_2203	1.364e-37	149.0	COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,1I0I9@117743|Flavobacteriia,2PBX4@246874|Cryomorphaceae	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH2_k127_8862153_4	983548.Krodi_0807	7.829e-82	289.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,1HYW1@117743|Flavobacteriia,37E2B@326319|Dokdonia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH2_k127_8862153_1	1408473.JHXO01000001_gene2245	2.813e-96	327.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,2FMFG@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH2_k127_8862153_2	1168289.AJKI01000031_gene1088	9.871e-93	319.0	COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,2G3HG@200643|Bacteroidia,3XJX6@558415|Marinilabiliaceae	976|Bacteroidetes	S	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
DTH2_k127_8862749_2	880073.Calab_2101	8.918e-09	61.0	COG1361@1|root,COG2911@1|root,COG4935@1|root,COG1361@2|Bacteria,COG2911@2|Bacteria,COG4935@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
DTH2_k127_8862749_1	999419.HMPREF1077_01959	8.527e-110	368.0	COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia,22X1B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Efflux ABC transporter, permease protein	lolE	-	-	ko:K09808,ko:K09815	ko02010,map02010	M00242,M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125,3.A.1.15.3,3.A.1.15.5	-	-	FtsX,MacB_PCD
DTH2_k127_8862749_0	391625.PPSIR1_18015	4.048e-126	415.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42NA7@68525|delta/epsilon subdivisions,2WIN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
DTH2_k127_8876520_0	1168289.AJKI01000063_gene3456	1.98e-261	823.0	COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,3XJ5R@558415|Marinilabiliaceae	976|Bacteroidetes	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
DTH2_k127_8880844_2	933262.AXAM01000018_gene991	0.0002063	54.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	pilV	GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840	-	ko:K02457,ko:K02458,ko:K10926,ko:K10930,ko:K10931	ko03070,ko05110,ko05111,map03070,map05110,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,Shufflon_N,TcpA
DTH2_k127_8880844_0	1121448.DGI_2669	8.303e-19	93.0	COG2165@1|root,COG2165@2|Bacteria,1NMAP@1224|Proteobacteria,42WV2@68525|delta/epsilon subdivisions,2WSU0@28221|Deltaproteobacteria,2ME2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH2_k127_8880844_1	1122918.KB907265_gene1075	3.462e-12	77.0	29IXR@1|root,305V4@2|Bacteria,1TYQY@1239|Firmicutes,4I7VX@91061|Bacilli,26XUQ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8896293_1	886379.AEWI01000004_gene881	4.34e-129	416.0	COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,2FNY1@200643|Bacteroidia,3XKQW@558415|Marinilabiliaceae	976|Bacteroidetes	G	mannose-6-phosphate isomerase, class I	-	-	-	-	-	-	-	-	-	-	-	-	ROK
DTH2_k127_8896293_0	1122605.KB893638_gene3449	6.21e-307	958.0	COG1874@1|root,COG1874@2|Bacteria,4NE2P@976|Bacteroidetes,1IVNZ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 35	bga_1	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,F5_F8_type_C,Glyco_hydro_35,Glyco_hydro_43
DTH2_k127_8896293_2	1077285.AGDG01000045_gene2966	0.0007442	43.0	COG1482@1|root,COG1940@1|root,COG1482@2|Bacteria,COG1940@2|Bacteria,4NF9A@976|Bacteroidetes,2FNY1@200643|Bacteroidia,4AMYT@815|Bacteroidaceae	976|Bacteroidetes	G	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	ROK
DTH2_k127_8896597_0	1408473.JHXO01000010_gene3549	8.842e-259	805.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FNCD@200643|Bacteroidia	976|Bacteroidetes	I	Carboxyl transferase domain protein	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH2_k127_8896597_2	1410608.JNKX01000014_gene654	1.482e-46	173.0	COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,2FNTU@200643|Bacteroidia,4AMGT@815|Bacteroidaceae	976|Bacteroidetes	I	Biotin-requiring enzyme	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
DTH2_k127_8896597_1	1168034.FH5T_18240	8.466e-221	694.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,2FMBN@200643|Bacteroidia	976|Bacteroidetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH2_k127_8896597_3	1121904.ARBP01000011_gene1396	1.267e-16	94.0	COG1404@1|root,COG1572@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_8896597_4	1185876.BN8_02520	2.315e-06	61.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,4NN1P@976|Bacteroidetes,47T2G@768503|Cytophagia	976|Bacteroidetes	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8913723_3	945713.IALB_1057	1.671e-139	463.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	3.4.17.22	ko:K06987,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,PKD,Peptidase_M14
DTH2_k127_8913723_4	468059.AUHA01000004_gene2183	2.178e-105	349.0	COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH2_k127_8913723_7	1296415.JACC01000002_gene3314	1.038e-08	64.0	2E7SQ@1|root,3327W@2|Bacteria,4NUWY@976|Bacteroidetes,1I5CR@117743|Flavobacteriia,2YJ7K@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8913723_1	929556.Solca_2898	5.414e-183	588.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1IRBF@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DTH2_k127_8913723_0	1392490.JHZX01000001_gene164	0.0	1045.0	COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1HX2R@117743|Flavobacteriia	976|Bacteroidetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DTH2_k127_8913723_2	1123234.AUKI01000011_gene1389	6.137e-149	482.0	COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,1HWW0@117743|Flavobacteriia	976|Bacteroidetes	M	glucose-1-phosphate thymidylyltransferase	glmU	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
DTH2_k127_8913723_6	1122621.ATZA01000003_gene1348	2.705e-37	141.0	COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,1ISRC@117747|Sphingobacteriia	976|Bacteroidetes	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DTH2_k127_8913723_5	1237149.C900_05081	2.806e-69	241.0	COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,47K6Q@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH2_k127_8914554_0	927658.AJUM01000015_gene3169	4.652e-276	870.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia,3XJ97@558415|Marinilabiliaceae	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8914554_1	742817.HMPREF9449_01135	2.091e-36	143.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,2FP9S@200643|Bacteroidia,22X52@171551|Porphyromonadaceae	976|Bacteroidetes	S	Endonuclease exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_8929626_3	1121904.ARBP01000030_gene1942	4.672e-91	309.0	COG0628@1|root,COG0628@2|Bacteria,4NN3B@976|Bacteroidetes,47UN9@768503|Cytophagia	976|Bacteroidetes	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_8929626_8	1121373.KB903643_gene3493	2.477e-52	203.0	COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia	976|Bacteroidetes	M	PFAM surface antigen variable number repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_8929626_2	1121373.KB903664_gene2661	2.885e-108	364.0	COG0729@1|root,COG0729@2|Bacteria,4PMQ2@976|Bacteroidetes,47YNU@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
DTH2_k127_8929626_4	1121904.ARBP01000011_gene1461	3.333e-72	248.0	28N4A@1|root,2ZB9T@2|Bacteria,4NS50@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
DTH2_k127_8929626_5	1121904.ARBP01000011_gene1462	2.358e-68	237.0	COG3637@1|root,COG3637@2|Bacteria,4NTRC@976|Bacteroidetes,47SSV@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DTH2_k127_8929626_9	1121904.ARBP01000003_gene6560	2.386e-41	157.0	2CWBN@1|root,32SZD@2|Bacteria,4NU6S@976|Bacteroidetes,47VSE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8929626_6	626522.GCWU000325_00737	3.927e-63	230.0	2BWJ3@1|root,2Z8E8@2|Bacteria,4NI7Z@976|Bacteroidetes,2FNX1@200643|Bacteroidia,1WDTE@1283313|Alloprevotella	976|Bacteroidetes	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_8929626_10	373994.Riv7116_3686	1.204e-30	130.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8,Trypsin_2
DTH2_k127_8929626_7	1121335.Clst_2381	4.796e-53	191.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,3WK3U@541000|Ruminococcaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,Nitroreductase
DTH2_k127_8929626_11	1122179.KB890425_gene3448	4.395e-24	111.0	COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,1IZ7F@117747|Sphingobacteriia	976|Bacteroidetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292,LolA_like
DTH2_k127_8929626_0	204669.Acid345_3021	0.0	1049.0	COG4447@1|root,COG4447@2|Bacteria,3Y6ZR@57723|Acidobacteria	57723|Acidobacteria	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_8929626_1	1408473.JHXO01000008_gene2798	2.601e-137	456.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_8940531_1	1379858.N508_00585	4.96e-49	188.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8940531_0	1197477.IA57_00565	8.14e-128	424.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
DTH2_k127_8954068_0	927658.AJUM01000012_gene2689	1.575e-215	691.0	COG1629@1|root,COG4771@2|Bacteria,4NE7A@976|Bacteroidetes,2FQ61@200643|Bacteroidia	976|Bacteroidetes	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,HMA,Plug,TonB_dep_Rec
DTH2_k127_8954068_1	1123277.KB893192_gene4325	7.609e-27	113.0	COG2608@1|root,COG2608@2|Bacteria,4NUTQ@976|Bacteroidetes,47S0M@768503|Cytophagia	976|Bacteroidetes	P	PFAM Heavy metal transport detoxification protein	-	-	-	ko:K08364	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	HMA
DTH2_k127_8966618_3	459349.CLOAM1790	7.572e-17	95.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
DTH2_k127_8966618_4	1218103.CIN01S_03_00750	8.743e-05	55.0	COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1HYKJ@117743|Flavobacteriia,3ZR43@59732|Chryseobacterium	976|Bacteroidetes	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH2_k127_8966618_0	1121904.ARBP01000028_gene1647	2.358e-200	651.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_8966618_5	504472.Slin_2122	0.0004549	53.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	DUF11,Gram_pos_anchor,SdrD_B
DTH2_k127_8966618_1	926562.Oweho_2044	1.749e-44	184.0	2EW37@1|root,33PGF@2|Bacteria,4P22D@976|Bacteroidetes,1I7PK@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_8966618_2	1410674.JNKU01000024_gene2006	1.216e-30	122.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,4HB4B@91061|Bacilli,3F5WT@33958|Lactobacillaceae	91061|Bacilli	S	Putative esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH2_k127_8969054_0	926562.Oweho_1031	9.119e-92	323.0	COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,1HY7M@117743|Flavobacteriia	976|Bacteroidetes	E	Aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
DTH2_k127_8969054_5	1408473.JHXO01000008_gene2893	4.535e-68	238.0	COG1794@1|root,COG1794@2|Bacteria,4NM9B@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
DTH2_k127_8969054_6	1286632.P278_00790	2.011e-47	173.0	COG3070@1|root,COG3070@2|Bacteria,4NSGZ@976|Bacteroidetes,1I4CE@117743|Flavobacteriia	976|Bacteroidetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
DTH2_k127_8969054_4	929556.Solca_0796	1.852e-70	242.0	COG2110@1|root,COG2110@2|Bacteria,4NNRH@976|Bacteroidetes,1IS3E@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
DTH2_k127_8969054_7	1047013.AQSP01000092_gene313	4.44e-34	134.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH2_k127_8969054_1	1124780.ANNU01000038_gene186	1.068e-90	313.0	COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,47JE6@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_8969054_3	1235815.BAIX01000013_gene1264	4.531e-86	290.0	COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia	976|Bacteroidetes	K	transcriptional regulatory protein	rprY	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_8969054_2	929703.KE386491_gene3290	5.368e-87	304.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,47Y16@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_8975284_0	1195236.CTER_2030	5.554e-30	137.0	COG1215@1|root,COG1215@2|Bacteria,1V4HY@1239|Firmicutes	1239|Firmicutes	M	(COG0463), glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glyco_transf_7C,Glycos_transf_2
DTH2_k127_8975284_2	598659.NAMH_1654	9.681e-22	110.0	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,43BJ3@68525|delta/epsilon subdivisions,2YT90@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_8975284_1	266779.Meso_0488	3.817e-25	117.0	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,2TW80@28211|Alphaproteobacteria,43RR4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_901614_1	744872.Spica_2162	9.18e-24	109.0	COG2454@1|root,COG2454@2|Bacteria,2JADQ@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
DTH2_k127_901614_0	1408473.JHXO01000006_gene1174	2.54e-159	515.0	COG1629@1|root,COG4771@2|Bacteria,4NEHN@976|Bacteroidetes,2FNEZ@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_901809_2	1392488.JHZY01000002_gene1019	5.121e-22	100.0	2EI44@1|root,33BVH@2|Bacteria,4NZCQ@976|Bacteroidetes,1I697@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_901809_4	236814.IX39_03450	1.155e-06	62.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,3ZPFB@59732|Chryseobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
DTH2_k127_901809_1	1453500.AT05_05380	5.089e-41	173.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Alginate_lyase,BNR_2,Exo_endo_phos,F5_F8_type_C,Laminin_G_3,Metallophos,PA14,SASA,SLH
DTH2_k127_901809_0	331678.Cphamn1_2471	2.707e-123	404.0	COG0167@1|root,COG0167@2|Bacteria,1FDV5@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH2_k127_901809_3	927658.AJUM01000047_gene2811	9.898e-17	83.0	COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,2FN98@200643|Bacteroidia,3XJXZ@558415|Marinilabiliaceae	976|Bacteroidetes	M	PDZ domain (Also known as DHR or GLGF)	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH2_k127_9022524_0	1121129.KB903360_gene3192	1.904e-103	340.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,2FRF9@200643|Bacteroidia,22WJD@171551|Porphyromonadaceae	976|Bacteroidetes	C	Inorganic pyrophosphatase	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
DTH2_k127_9022524_1	1461577.CCMH01000016_gene289	5.484e-72	249.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1HWX6@117743|Flavobacteriia	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DTH2_k127_9022524_2	485917.Phep_0401	3.843e-10	64.0	COG0392@1|root,COG0392@2|Bacteria,4NI8Y@976|Bacteroidetes,1IP3F@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DTH2_k127_903380_2	1121897.AUGO01000001_gene1525	3.837e-15	87.0	COG3307@1|root,COG3307@2|Bacteria,4NT17@976|Bacteroidetes,1IKJI@117743|Flavobacteriia,2NUJQ@237|Flavobacterium	976|Bacteroidetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH2_k127_903380_1	1239415.CM001837_gene1084	1.321e-61	219.0	COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1HXT6@117743|Flavobacteriia,37ESA@326319|Dokdonia	976|Bacteroidetes	M	CoA-binding domain	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
DTH2_k127_903380_0	700598.Niako_4341	2.491e-68	243.0	COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes,1IT5C@117747|Sphingobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
DTH2_k127_903380_3	1123284.KB899045_gene2388	9.846e-07	57.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli	91061|Bacilli	M	epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GAF_3,GDP_Man_Dehyd
DTH2_k127_9053596_2	385682.AFSL01000100_gene37	1.318e-68	241.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,2FM1J@200643|Bacteroidia,3XJIH@558415|Marinilabiliaceae	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
DTH2_k127_9053596_4	1121904.ARBP01000009_gene4379	7.433e-53	194.0	2DICZ@1|root,32UAY@2|Bacteria,4NU7D@976|Bacteroidetes,47SYM@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9053596_1	926562.Oweho_1781	2.771e-123	405.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IK35@117743|Flavobacteriia,2PAH3@246874|Cryomorphaceae	976|Bacteroidetes	H	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
DTH2_k127_9053596_6	929556.Solca_1445	1.534e-22	105.0	2ATWF@1|root,31JFP@2|Bacteria,4NQPB@976|Bacteroidetes,1ITBA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9053596_3	485918.Cpin_2014	2.667e-59	220.0	COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,1IUIH@117747|Sphingobacteriia	976|Bacteroidetes	N	Domain of unknown function (DUF4421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4421
DTH2_k127_9053596_5	1313421.JHBV01000014_gene3816	2.74e-29	129.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4NRAB@976|Bacteroidetes	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calycin_like,PCMD
DTH2_k127_9053596_0	755732.Fluta_1488	5.02e-186	597.0	COG4206@1|root,COG4206@2|Bacteria,4NIJS@976|Bacteroidetes	976|Bacteroidetes	H	COG4206 Outer membrane cobalamin receptor protein	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_9060174_6	1408473.JHXO01000010_gene3615	7.555e-37	141.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,4PNHR@976|Bacteroidetes	976|Bacteroidetes	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoaC
DTH2_k127_9060174_10	6238.CBG01253	1.086e-07	55.0	COG2272@1|root,KOG1516@2759|Eukaryota,39BDH@33154|Opisthokonta,3CFFM@33208|Metazoa,3DWVT@33213|Bilateria,40HZ1@6231|Nematoda,1M17N@119089|Chromadorea,40SNC@6236|Rhabditida	33208|Metazoa	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
DTH2_k127_9060174_8	1270196.JCKI01000006_gene2719	4.391e-19	89.0	COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1IYQM@117747|Sphingobacteriia	976|Bacteroidetes	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
DTH2_k127_9060174_0	1094466.KQS_09465	8.955e-234	749.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1HWZJ@117743|Flavobacteriia,2NTZ0@237|Flavobacterium	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DTH2_k127_9060174_1	1453500.AT05_08775	1.417e-133	433.0	COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,1HWWG@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
DTH2_k127_9060174_9	760192.Halhy_4114	4.449e-14	76.0	2C5EY@1|root,31EA9@2|Bacteria,4NYA8@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
DTH2_k127_9060174_11	1089547.KB913013_gene3331	1.919e-07	57.0	2DS7U@1|root,33EX4@2|Bacteria,4NZKK@976|Bacteroidetes,47SMW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
DTH2_k127_9060174_2	1121895.Q765_08955	8.57e-121	398.0	COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,1HZBE@117743|Flavobacteriia,2NT03@237|Flavobacterium	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
DTH2_k127_9060174_5	1048983.EL17_20750	1.89e-72	258.0	COG0628@1|root,COG0628@2|Bacteria,4NNA1@976|Bacteroidetes,47PFK@768503|Cytophagia	976|Bacteroidetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH2_k127_9060174_4	1121904.ARBP01000015_gene210	8.918e-93	322.0	28ID4@1|root,2Z8FC@2|Bacteria,4NFYZ@976|Bacteroidetes,47NAT@768503|Cytophagia	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9060174_3	1123008.KB905695_gene2629	4.098e-97	322.0	COG1131@1|root,COG1131@2|Bacteria,4NDV7@976|Bacteroidetes,2FN84@200643|Bacteroidia,22XIR@171551|Porphyromonadaceae	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_9060174_7	1121904.ARBP01000001_gene5529	2.184e-29	125.0	COG3203@1|root,COG3203@2|Bacteria,4PKUC@976|Bacteroidetes,47YNV@768503|Cytophagia	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_9068076_7	1183438.GKIL_1432	7.698e-65	234.0	COG0500@1|root,COG2226@2|Bacteria,1G0WT@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
DTH2_k127_9068076_11	402612.FP2276	1.923e-08	62.0	2CE7N@1|root,30Q80@2|Bacteria,4NNKP@976|Bacteroidetes,1I2K6@117743|Flavobacteriia,2NWH2@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9068076_6	485918.Cpin_6848	1.035e-73	259.0	COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,1IPPX@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
DTH2_k127_9068076_10	985867.AEWF01000001_gene2197	2.574e-10	64.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,2UHI1@28211|Alphaproteobacteria,47GG3@766|Rickettsiales	766|Rickettsiales	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH2_k127_9068076_8	1123242.JH636434_gene4759	2.368e-57	213.0	2BWJ3@1|root,2Z7IQ@2|Bacteria,2IX8R@203682|Planctomycetes	203682|Planctomycetes	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
DTH2_k127_9068076_1	203275.BFO_1823	7.295e-191	603.0	COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,2FQY5@200643|Bacteroidia	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH2_k127_9068076_2	313606.M23134_06289	2.004e-188	615.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,47XXH@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DTH2_k127_9068076_5	869213.JCM21142_83143	5.756e-108	359.0	COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,47NUW@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH2_k127_9068076_0	1168289.AJKI01000011_gene492	1.507e-266	840.0	COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,3XINU@558415|Marinilabiliaceae	976|Bacteroidetes	J	Elongation factor G, domain IV	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH2_k127_9068076_4	1305737.JAFX01000001_gene1435	6.319e-111	369.0	COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,47JCR@768503|Cytophagia	976|Bacteroidetes	S	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_9068076_3	880073.Calab_0643	2.594e-125	411.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH2_k127_9068105_0	385682.AFSL01000026_gene637	8.644e-262	827.0	COG0574@1|root,COG0574@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia,3XJKN@558415|Marinilabiliaceae	976|Bacteroidetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
DTH2_k127_9072403_4	1408473.JHXO01000005_gene1852	4.092e-64	221.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia	976|Bacteroidetes	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
DTH2_k127_9072403_7	1107311.Q767_13435	1.876e-11	74.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,2NWCZ@237|Flavobacterium	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_9072403_6	1499967.BAYZ01000045_gene2673	2.187e-52	199.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH2_k127_9072403_0	1379698.RBG1_1C00001G1676	6.748e-139	447.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2NPBE@2323|unclassified Bacteria	2|Bacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
DTH2_k127_9072403_3	1382306.JNIM01000001_gene3630	1.133e-69	246.0	COG3752@1|root,COG3752@2|Bacteria,2G9CW@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
DTH2_k127_9072403_5	344747.PM8797T_10809	6.199e-59	214.0	COG1506@1|root,COG1506@2|Bacteria,2IXED@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
DTH2_k127_9072403_1	393921.HQ45_06045	4.612e-96	320.0	COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,2FR40@200643|Bacteroidia,22XAX@171551|Porphyromonadaceae	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ydfG	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_9072403_2	694427.Palpr_2908	2.952e-82	280.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,2FNK9@200643|Bacteroidia,22WFS@171551|Porphyromonadaceae	976|Bacteroidetes	I	Long-chain fatty acid--CoA ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_9077272_3	269798.CHU_3103	1.114e-06	55.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6,Peptidase_S8,TIG
DTH2_k127_9077272_2	1408473.JHXO01000015_gene1906	3.479e-17	93.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
DTH2_k127_9077272_1	1317122.ATO12_03780	1.452e-61	237.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia,2YGNW@290174|Aquimarina	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_12,TPR_7,TPR_8
DTH2_k127_9077272_0	1453498.LG45_07295	2.327e-62	222.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1I3FD@117743|Flavobacteriia,2P0EI@237|Flavobacterium	976|Bacteroidetes	T	LytTR family two component system response regulatory protein	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_908288_1	497964.CfE428DRAFT_1804	6.215e-44	171.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH2_k127_908288_0	1396141.BATP01000002_gene4845	9.629e-67	233.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH2_k127_9089088_1	755732.Fluta_0362	2.288e-61	214.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2PAGA@246874|Cryomorphaceae	976|Bacteroidetes	V	TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
DTH2_k127_9089088_0	1519464.HY22_01410	3.882e-85	293.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
DTH2_k127_9089088_2	96561.Dole_1791	3.488e-43	176.0	COG1044@1|root,COG1361@1|root,COG1653@1|root,COG1044@2|Bacteria,COG1361@2|Bacteria,COG1653@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9114297_4	1122605.KB893633_gene4263	3.852e-18	86.0	COG0382@1|root,COG0382@2|Bacteria,4NFRM@976|Bacteroidetes,1IYC2@117747|Sphingobacteriia	976|Bacteroidetes	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH2_k127_9114297_1	555500.I215_03078	2.12e-56	202.0	COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,1I1FS@117743|Flavobacteriia	976|Bacteroidetes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_3
DTH2_k127_9114297_2	468059.AUHA01000004_gene2261	5.434e-56	205.0	COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,1IRXA@117747|Sphingobacteriia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
DTH2_k127_9114297_0	1123057.P872_05335	5.689e-85	291.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia	976|Bacteroidetes	K	PFAM MerR family regulatory protein	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
DTH2_k127_9114297_3	869213.JCM21142_72	6.703e-27	112.0	COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,47KPZ@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	sigR_3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH2_k127_9124517_0	755732.Fluta_0535	2.252e-66	251.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,1I7MT@117743|Flavobacteriia,2PAFS@246874|Cryomorphaceae	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
DTH2_k127_9124517_2	1122931.AUAE01000006_gene3095	1.146e-08	65.0	COG1555@1|root,COG1555@2|Bacteria,4NUGB@976|Bacteroidetes,2FUT7@200643|Bacteroidia,231NR@171551|Porphyromonadaceae	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9124517_1	331678.Cphamn1_2390	6.138e-60	214.0	COG5587@1|root,COG5587@2|Bacteria,1FEPB@1090|Chlorobi	1090|Chlorobi	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
DTH2_k127_9150206_6	1189612.A33Q_4473	4.211e-08	54.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
DTH2_k127_9150206_7	1250278.JQNQ01000001_gene3587	0.0001414	46.0	2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Cbb3-type cytochrome oxidase component FixQ	ccoQ	-	-	-	-	-	-	-	-	-	-	-	FixQ
DTH2_k127_9150206_2	1121904.ARBP01000002_gene7144	2.296e-59	211.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
DTH2_k127_9150206_0	1121904.ARBP01000002_gene7145	1.386e-165	533.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase accessory protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
DTH2_k127_9150206_4	929562.Emtol_0364	3.011e-21	99.0	COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,47YSU@768503|Cytophagia	976|Bacteroidetes	P	PFAM FixH	ccoH	-	-	-	-	-	-	-	-	-	-	-	FixH
DTH2_k127_9150206_1	869213.JCM21142_321	6.477e-68	238.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
DTH2_k127_9150206_5	643867.Ftrac_2700	3.011e-18	95.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,4NEXP@976|Bacteroidetes,47RM9@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	nirK	-	1.7.2.1	ko:K00368,ko:K00405	ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020	M00156,M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cu-oxidase,Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3
DTH2_k127_9150206_3	1189612.A33Q_1700	7.776e-25	110.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
DTH2_k127_9152219_0	1408473.JHXO01000008_gene2886	7.594e-276	871.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
DTH2_k127_9152219_2	1121904.ARBP01000072_gene282	1.307e-178	587.0	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia	976|Bacteroidetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH2_k127_9152219_6	760192.Halhy_3856	1.06e-11	68.0	2E1JK@1|root,32WX8@2|Bacteria,4NTME@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9152219_4	1120951.AUBG01000001_gene829	1.395e-111	373.0	COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1HZFG@117743|Flavobacteriia	976|Bacteroidetes	M	Transporter	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
DTH2_k127_9152219_1	1237149.C900_04093	6.458e-193	612.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH2_k127_9152219_3	1408473.JHXO01000005_gene1744	2.087e-121	404.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,2FP7E@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH2_k127_9152219_5	1121289.JHVL01000007_gene2726	3.243e-17	87.0	2E7HQ@1|root,33207@2|Bacteria,1VT77@1239|Firmicutes,24FMI@186801|Clostridia,36PKH@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF4231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
DTH2_k127_9155356_1	929556.Solca_3842	4.042e-178	589.0	COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,1J0XD@117747|Sphingobacteriia	976|Bacteroidetes	D	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
DTH2_k127_9155356_4	643867.Ftrac_2380	1.386e-17	89.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
DTH2_k127_9155356_2	1237149.C900_03439	8.693e-40	152.0	COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,47Q9Q@768503|Cytophagia	976|Bacteroidetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	-	-	-	-	-	-	-	-	-	UPF0054
DTH2_k127_9155356_0	1313301.AUGC01000012_gene1356	8.213e-281	875.0	COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes	976|Bacteroidetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
DTH2_k127_9155356_3	1408473.JHXO01000010_gene3580	1.497e-19	102.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2FRVJ@200643|Bacteroidia	976|Bacteroidetes	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH2_k127_9159905_0	1408473.JHXO01000005_gene1510	6.576e-155	505.0	COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,2FNDE@200643|Bacteroidia	976|Bacteroidetes	CO	cytochrome c biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH2_k127_9172718_0	163908.KB235896_gene2298	1.626e-51	204.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1GJ7F@1117|Cyanobacteria,1HQZ9@1161|Nostocales	1117|Cyanobacteria	QU	Domains in Na-Ca exchangers and integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
DTH2_k127_9172718_1	1454007.JAUG01000073_gene4088	3.566e-21	109.0	COG5295@1|root,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes	976|Bacteroidetes	UW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	4.2.2.20,4.2.2.21	ko:K08961	-	-	-	-	ko00000,ko01000	-	-	-	Lyase_8,Lyase_catalyt
DTH2_k127_9177600_2	742766.HMPREF9455_01980	3.528e-29	119.0	COG0009@1|root,COG0009@2|Bacteria,4NM43@976|Bacteroidetes,2FPW5@200643|Bacteroidia,22XN8@171551|Porphyromonadaceae	976|Bacteroidetes	J	Belongs to the SUA5 family	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
DTH2_k127_9177600_1	886379.AEWI01000030_gene306	6.744e-74	256.0	COG0212@1|root,COG0388@1|root,COG0212@2|Bacteria,COG0388@2|Bacteria,4NQRG@976|Bacteroidetes,2FQQB@200643|Bacteroidia,3XJW7@558415|Marinilabiliaceae	976|Bacteroidetes	H	5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
DTH2_k127_9177600_0	1408473.JHXO01000007_gene849	9.394e-158	504.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,2FQB7@200643|Bacteroidia	976|Bacteroidetes	C	dehydrogenase E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DTH2_k127_919375_2	158189.SpiBuddy_0143	2.29e-08	60.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
DTH2_k127_919375_0	1235803.C825_01273	1.056e-176	564.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,22VW2@171551|Porphyromonadaceae	976|Bacteroidetes	S	hydrolase activity, acting on glycosyl bonds	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH2_k127_919375_1	929556.Solca_2551	6.541e-20	92.0	COG0518@1|root,COG0518@2|Bacteria,4NMFC@976|Bacteroidetes,1ISTT@117747|Sphingobacteriia	976|Bacteroidetes	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DTH2_k127_919840_0	411477.PARMER_00600	1.978e-266	831.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,2FN7Y@200643|Bacteroidia,22XPZ@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH2_k127_9244915_5	1121373.KB903625_gene3159	8.839e-59	212.0	COG3279@1|root,COG3279@2|Bacteria,4NPFH@976|Bacteroidetes,47XE8@768503|Cytophagia	976|Bacteroidetes	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_9244915_2	1123277.KB893174_gene5927	8.428e-173	580.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
DTH2_k127_9244915_7	755732.Fluta_2233	1.785e-10	68.0	COG2146@1|root,COG2146@2|Bacteria,4PFBM@976|Bacteroidetes,1ICTH@117743|Flavobacteriia,2PC3S@246874|Cryomorphaceae	976|Bacteroidetes	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9244915_0	742767.HMPREF9456_00506	1.993e-249	775.0	COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,2FPWZ@200643|Bacteroidia,22W9Y@171551|Porphyromonadaceae	976|Bacteroidetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH2_k127_9244915_6	1408813.AYMG01000011_gene832	1.168e-37	150.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1ITW4@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
DTH2_k127_9244915_3	925409.KI911562_gene1461	1.788e-86	292.0	COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,1IW5Q@117747|Sphingobacteriia	976|Bacteroidetes	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)	pcrB	-	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
DTH2_k127_9244915_1	880073.Calab_0270	3.594e-219	701.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K06889,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DTH2_k127_9244915_4	1122931.AUAE01000011_gene1732	8.804e-63	226.0	COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,2FNR3@200643|Bacteroidia,22XU0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH2_k127_9269259_1	929704.Myrod_1885	1.347e-61	218.0	COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1HWT8@117743|Flavobacteriia,47HED@76831|Myroides	976|Bacteroidetes	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH2_k127_9269259_0	929713.NIASO_05310	2.821e-185	586.0	COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,1IUVG@117747|Sphingobacteriia	976|Bacteroidetes	G	Phosphofructokinase	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DTH2_k127_9282088_1	984262.SGRA_1773	1.071e-13	73.0	28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,1IU2K@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9282088_0	1168034.FH5T_12525	6.169e-188	595.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,2FWPF@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9282088_2	1121012.AUKX01000014_gene2705	6.032e-12	76.0	COG1629@1|root,COG1629@2|Bacteria,4PNHX@976|Bacteroidetes,1IK6J@117743|Flavobacteriia	976|Bacteroidetes	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DTH2_k127_9290189_0	1034943.BN1094_00784	1.253e-19	105.0	2A30Q@1|root,30RFE@2|Bacteria,1QC14@1224|Proteobacteria,1T7NU@1236|Gammaproteobacteria,1JFM0@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9291163_1	385682.AFSL01000026_gene663	4.191e-158	505.0	COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,2FPIT@200643|Bacteroidia,3XISD@558415|Marinilabiliaceae	976|Bacteroidetes	U	SecY translocase	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DTH2_k127_9291163_3	1349822.NSB1T_12175	9.839e-113	369.0	COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,2FM24@200643|Bacteroidia,22X5Z@171551|Porphyromonadaceae	976|Bacteroidetes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DTH2_k127_9291163_9	1408433.JHXV01000034_gene44	6.935e-39	145.0	COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1I3WQ@117743|Flavobacteriia,2PB2F@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH2_k127_9291163_10	755732.Fluta_0757	4.569e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1I6A2@117743|Flavobacteriia,2PC34@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
DTH2_k127_9291163_8	1237149.C900_01060	2.54e-55	196.0	COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,47PRH@768503|Cytophagia	976|Bacteroidetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DTH2_k127_9291163_6	742726.HMPREF9448_02453	2.7e-66	227.0	COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,2FRZD@200643|Bacteroidia,22XN9@171551|Porphyromonadaceae	976|Bacteroidetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DTH2_k127_9291163_5	1122621.ATZA01000014_gene3234	8.748e-89	296.0	COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,1INSQ@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DTH2_k127_9291163_2	1408433.JHXV01000034_gene48	1.441e-154	494.0	COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,1HX6J@117743|Flavobacteriia,2PA8U@246874|Cryomorphaceae	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DTH2_k127_9291163_7	1168034.FH5T_12945	4.124e-60	214.0	COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia	976|Bacteroidetes	J	50S ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
DTH2_k127_9291163_0	1185876.BN8_06622	1.393e-207	653.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia	976|Bacteroidetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DTH2_k127_9291163_4	1408473.JHXO01000010_gene3749	7.14e-92	317.0	COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,2FXEQ@200643|Bacteroidia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
DTH2_k127_9306819_1	153721.MYP_1116	2.681e-43	165.0	2BFNJ@1|root,329GZ@2|Bacteria,4NNZM@976|Bacteroidetes,47QZK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	Ceramidase
DTH2_k127_9306819_2	1121459.AQXE01000001_gene2822	1.032e-40	162.0	COG2865@1|root,COG2865@2|Bacteria,1R919@1224|Proteobacteria,430FX@68525|delta/epsilon subdivisions,2WVTJ@28221|Deltaproteobacteria,2M90R@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	AAA-4 family	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
DTH2_k127_9306819_0	1191523.MROS_1278	1.843e-53	194.0	COG1656@1|root,COG1656@2|Bacteria	2|Bacteria	F	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
DTH2_k127_9311286_0	153721.MYP_4265	1.607e-125	417.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,47N4W@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH2_k127_9311286_1	153721.MYP_4266	8.529e-77	271.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,47PQU@768503|Cytophagia	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
DTH2_k127_9339536_2	385682.AFSL01000090_gene951	4.75e-76	270.0	COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,2FPG5@200643|Bacteroidia,3XJX7@558415|Marinilabiliaceae	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	rprX	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH2_k127_9339536_3	313606.M23134_01094	5.791e-75	258.0	COG0745@1|root,COG0745@2|Bacteria,4NH5Q@976|Bacteroidetes,47UTX@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_9339536_0	1047013.AQSP01000103_gene1160	8.402e-309	960.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH2_k127_9339536_1	926562.Oweho_1295	6.911e-224	717.0	COG1629@1|root,COG4771@2|Bacteria,4PPAD@976|Bacteroidetes	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_9339536_4	509635.N824_15580	1.45e-07	54.0	2AX7X@1|root,31P6Q@2|Bacteria,4NGGX@976|Bacteroidetes,1IURY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9346594_3	643867.Ftrac_2519	1.321e-13	84.0	COG2356@1|root,COG2356@2|Bacteria,4NEGS@976|Bacteroidetes	976|Bacteroidetes	L	Nuclease, EndA NucM family	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,LTD,fn3
DTH2_k127_9346594_0	459349.CLOAM1622	2.623e-67	250.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM
DTH2_k127_9346594_1	1122176.KB903540_gene20	5.729e-49	195.0	COG0526@1|root,COG1404@1|root,COG0526@2|Bacteria,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	AhpC-TSA,B_lectin,Omp28
DTH2_k127_9346594_4	1313301.AUGC01000011_gene1147	3.85e-10	69.0	2AEI8@1|root,314DM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9346594_2	243275.TDE_1690	1.477e-34	140.0	COG0317@1|root,COG0317@2|Bacteria,2J5Q1@203691|Spirochaetes	203691|Spirochaetes	KT	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	-
DTH2_k127_9349404_2	1121129.KB903359_gene2100	4.379e-62	218.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes,2FN09@200643|Bacteroidia,22X19@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative modulator of DNA gyrase	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DTH2_k127_9349404_3	234267.Acid_5820	1.843e-54	213.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
DTH2_k127_9349404_1	1408473.JHXO01000005_gene1789	2.01e-76	262.0	28P2C@1|root,2ZBYG@2|Bacteria,4NMEQ@976|Bacteroidetes,2FVCT@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9349404_0	1121904.ARBP01000009_gene4365	3.888e-213	683.0	COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47MZQ@768503|Cytophagia	976|Bacteroidetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DTH2_k127_9351714_1	1499967.BAYZ01000048_gene2703	3.879e-132	429.0	COG0252@1|root,COG0252@2|Bacteria	2|Bacteria	EJ	asparaginase activity	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DTH2_k127_9351714_2	1347342.BN863_1830	4.686e-92	308.0	COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,1HXZK@117743|Flavobacteriia	976|Bacteroidetes	U	Mota tolq exbb proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH2_k127_9351714_6	1120968.AUBX01000010_gene1436	5.754e-12	71.0	2E2VE@1|root,32XX2@2|Bacteria,4NUIE@976|Bacteroidetes,47RT3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9351714_4	886379.AEWI01000035_gene3050	3.86e-58	209.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,3XJ4Z@558415|Marinilabiliaceae	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
DTH2_k127_9351714_5	1168034.FH5T_05380	3.762e-49	180.0	COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,2FM42@200643|Bacteroidia	976|Bacteroidetes	U	Biopolymer transport protein, ExbD	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH2_k127_9351714_3	1408473.JHXO01000001_gene2054	2.99e-63	229.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,2FT47@200643|Bacteroidia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DTH2_k127_9351714_0	761193.Runsl_0390	1.056e-134	436.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
DTH2_k127_9351714_8	641143.HMPREF9331_02507	3.373e-06	51.0	COG3519@1|root,COG3519@2|Bacteria,4NF2N@976|Bacteroidetes,1HZ1R@117743|Flavobacteriia,1ERB9@1016|Capnocytophaga	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF5459
DTH2_k127_9365153_0	593750.Metfor_0515	4.176e-265	822.0	COG0661@1|root,arCOG01189@2157|Archaea,2XT2I@28890|Euryarchaeota,2N9FG@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM ABC-1 domain protein	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
DTH2_k127_9365455_0	929556.Solca_1191	2.05e-205	657.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
DTH2_k127_9365455_1	1237149.C900_05405	2.134e-05	52.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	ygaU	GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896	-	-	-	-	-	-	-	-	-	-	BON,LysM
DTH2_k127_9391234_3	1499967.BAYZ01000028_gene1315	6.296e-92	308.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH2_k127_9391234_2	153721.MYP_602	2.023e-95	321.0	COG0573@1|root,COG0573@2|Bacteria,4NEGX@976|Bacteroidetes,47TCC@768503|Cytophagia	976|Bacteroidetes	U	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DTH2_k127_9391234_0	153721.MYP_601	2.049e-101	337.0	COG0581@1|root,COG0581@2|Bacteria,4NHBW@976|Bacteroidetes,47UEW@768503|Cytophagia	976|Bacteroidetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DTH2_k127_9391234_1	1499967.BAYZ01000028_gene1312	2.411e-101	336.0	COG1117@1|root,COG1117@2|Bacteria,2NP2B@2323|unclassified Bacteria	2|Bacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27,3.6.3.55	ko:K02036,ko:K02068,ko:K06857	ko02010,map02010	M00186,M00211,M00222	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.7	-	-	ABC_tran
DTH2_k127_9401343_2	931276.Cspa_c17870	1.74e-25	119.0	COG3291@1|root,COG5263@1|root,COG3291@2|Bacteria,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Ricin_B_lectin,UnbV_ASPIC,VCBS,fn3
DTH2_k127_9401343_0	1124780.ANNU01000051_gene2095	4.156e-176	560.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
DTH2_k127_9401343_1	1034807.FBFL15_2654	2.407e-130	429.0	COG1373@1|root,COG1373@2|Bacteria,4NHQG@976|Bacteroidetes,1I2E3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DTH2_k127_9418804_1	459349.CLOAM0304	1.301e-28	127.0	COG1404@1|root,COG1404@2|Bacteria,2NQX6@2323|unclassified Bacteria	2|Bacteria	O	SPTR Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
DTH2_k127_9418804_0	471854.Dfer_1279	3.97e-54	197.0	COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia	976|Bacteroidetes	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_9425081_6	1121897.AUGO01000008_gene2545	1.259e-05	51.0	COG4886@1|root,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia,2NT0J@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
DTH2_k127_9425081_2	880073.Calab_2777	4.222e-77	273.0	COG1361@1|root,COG2356@1|root,COG1361@2|Bacteria,COG2356@2|Bacteria,2NQUF@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease I	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Endonuclease_1,Exo_endo_phos,FlgD_ig,Fn3-like,LTD
DTH2_k127_9425081_3	880073.Calab_1205	5.985e-51	203.0	COG1361@1|root,COG2133@1|root,COG2374@1|root,COG3420@1|root,COG1361@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3420@2|Bacteria,2NRB5@2323|unclassified Bacteria	2|Bacteria	G	Evidence 5 No homology to any previously reported sequences	xynX1	-	3.1.3.8,4.2.2.3	ko:K01083,ko:K01729,ko:K12287	ko00051,ko00562,map00051,map00562	-	R03371,R03706	RC00078	ko00000,ko00001,ko01000,ko02044	-	-	-	Beta_helix,Big_2,Exo_endo_phos,F5_F8_type_C,LTD,Laminin_G_3,SLH
DTH2_k127_9425081_5	1004785.AMBLS11_08130	1.419e-06	61.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,46500@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Extracellular nuclease	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
DTH2_k127_9425081_4	880071.Fleli_2825	1.263e-40	161.0	COG2340@1|root,COG2340@2|Bacteria,4NRNN@976|Bacteroidetes,47RRN@768503|Cytophagia	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
DTH2_k127_9425081_1	755732.Fluta_3899	6.007e-138	445.0	COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1HX04@117743|Flavobacteriia,2PA4I@246874|Cryomorphaceae	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
DTH2_k127_9425081_0	1408473.JHXO01000007_gene696	1.794e-148	485.0	COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,2FMER@200643|Bacteroidia	976|Bacteroidetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
DTH2_k127_9437043_2	1550091.JROE01000007_gene2755	6.055e-42	156.0	COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia	976|Bacteroidetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH2_k127_9437043_0	929556.Solca_1283	1.491e-180	572.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,1IQ0Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DTH2_k127_9437043_1	1168034.FH5T_18330	1.164e-58	229.0	COG0457@1|root,COG0457@2|Bacteria,4P3PK@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9455918_0	1122225.AULQ01000002_gene645	1.708e-66	252.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_12,TPR_8
DTH2_k127_9462568_2	1408473.JHXO01000001_gene2488	6.614e-64	229.0	COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
DTH2_k127_9462568_0	709991.Odosp_3395	5.412e-184	583.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,2FNNY@200643|Bacteroidia,22VV0@171551|Porphyromonadaceae	976|Bacteroidetes	S	membrane	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
DTH2_k127_9462568_8	393921.HQ45_00900	2.301e-07	59.0	COG0526@1|root,COG0526@2|Bacteria,4NNHX@976|Bacteroidetes,2FSTK@200643|Bacteroidia,22YUQ@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
DTH2_k127_9462568_1	945713.IALB_2736	3.022e-128	434.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
DTH2_k127_9462568_6	1519464.HY22_04545	4.022e-15	89.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSII_BNR,fn3
DTH2_k127_9462568_4	1122176.KB903565_gene3380	4.474e-30	136.0	COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1J10W@117747|Sphingobacteriia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB
DTH2_k127_9462568_5	1443665.JACA01000027_gene3893	6.568e-22	111.0	COG1044@1|root,COG1044@2|Bacteria,4PI4N@976|Bacteroidetes,1IGAK@117743|Flavobacteriia,2YKJV@290174|Aquimarina	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9462568_7	1453505.JASY01000015_gene4483	2.103e-14	87.0	COG5295@1|root,COG5295@2|Bacteria,4NE4G@976|Bacteroidetes,1HY8R@117743|Flavobacteriia,2NUIA@237|Flavobacterium	976|Bacteroidetes	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9462568_3	1385935.N836_20050	1.075e-47	178.0	COG1233@1|root,COG1233@2|Bacteria,1GCDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DTH2_k127_9470650_0	1122176.KB903532_gene2565	1.448e-196	648.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes	976|Bacteroidetes	M	sodium ion export across plasma membrane	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH2_k127_9470650_2	153721.MYP_3656	3.69e-35	147.0	COG0845@1|root,COG0845@2|Bacteria,4PB9N@976|Bacteroidetes,47VH9@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9470650_1	153721.MYP_3655	3.391e-43	165.0	COG5036@1|root,COG5036@2|Bacteria,4P2HI@976|Bacteroidetes,47V1T@768503|Cytophagia	976|Bacteroidetes	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH2_k127_9476687_2	1168034.FH5T_04825	3.954e-09	59.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia	976|Bacteroidetes	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH2_k127_9476687_0	1499967.BAYZ01000055_gene4858	1.458e-43	169.0	COG1409@1|root,COG1409@2|Bacteria,2NRSG@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH2_k127_9476687_1	667015.Bacsa_2447	4.859e-41	154.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia,4AKMW@815|Bacteroidaceae	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH2_k127_9502161_11	1123035.ARLA01000027_gene453	7.097e-14	73.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HWYE@117743|Flavobacteriia,4C2CS@83612|Psychroflexus	976|Bacteroidetes	E	Alanine dehydrogenase/PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_9502161_9	272559.BF9343_0620	3.35e-39	150.0	COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,2FS1V@200643|Bacteroidia,4AQKQ@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DTH2_k127_9502161_0	762903.Pedsa_2873	5.363e-206	652.0	COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,1IP34@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	porX	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
DTH2_k127_9502161_3	509635.N824_11460	7.557e-145	471.0	COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1IQIS@117747|Sphingobacteriia	976|Bacteroidetes	S	phosphohydrolase	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
DTH2_k127_9502161_4	1484460.JSWG01000006_gene3016	1.844e-142	459.0	COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,1HWJD@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
DTH2_k127_9502161_2	760192.Halhy_4709	7.68e-172	551.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,1IQB1@117747|Sphingobacteriia	976|Bacteroidetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
DTH2_k127_9502161_6	929556.Solca_4084	2.682e-119	388.0	COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,1IQ6Z@117747|Sphingobacteriia	976|Bacteroidetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH2_k127_9502161_10	269797.Mbar_A2782	2.364e-23	115.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02492@2157|Archaea,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG02532@2157|Archaea,2Y7Q0@28890|Euryarchaeota	28890|Euryarchaeota	KLT	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_3
DTH2_k127_9502161_8	468059.AUHA01000002_gene579	2.987e-54	198.0	COG1392@1|root,COG1392@2|Bacteria,4NI25@976|Bacteroidetes,1INNB@117747|Sphingobacteriia	976|Bacteroidetes	P	COGs COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DTH2_k127_9502161_5	886379.AEWI01000024_gene398	1.758e-135	447.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,2FNQZ@200643|Bacteroidia,3XIYR@558415|Marinilabiliaceae	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DTH2_k127_9502161_1	595494.Tola_2337	1.93e-177	566.0	COG1055@1|root,COG1055@2|Bacteria	2|Bacteria	P	arsenite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
DTH2_k127_9502161_7	232721.Ajs_3358	5.935e-119	390.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,4AA1C@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DTH2_k127_9502161_12	596327.PORUE0001_0392	4.754e-09	62.0	COG4206@1|root,COG4206@2|Bacteria,4NE1W@976|Bacteroidetes,2FME0@200643|Bacteroidia,22X63@171551|Porphyromonadaceae	976|Bacteroidetes	H	TonB-dependent receptor plug domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
DTH2_k127_9503559_0	504487.JCM19302_104	3.474e-61	218.0	COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia	976|Bacteroidetes	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH2_k127_9503559_3	643867.Ftrac_0155	4.654e-23	115.0	COG3291@1|root,COG3291@2|Bacteria,4NJAF@976|Bacteroidetes,47P0M@768503|Cytophagia	976|Bacteroidetes	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DTH2_k127_9503559_2	338966.Ppro_1478	1.229e-42	172.0	COG2382@1|root,COG2382@2|Bacteria,1MXJN@1224|Proteobacteria,43BHV@68525|delta/epsilon subdivisions,2X6WB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
DTH2_k127_9503559_1	1249997.JHZW01000002_gene1959	4.962e-57	206.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,1I232@117743|Flavobacteriia,2PICS@252356|Maribacter	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
DTH2_k127_9503559_4	1449076.JOOE01000004_gene369	8.035e-14	75.0	COG5285@1|root,COG5285@2|Bacteria,1R7DG@1224|Proteobacteria,2TTB2@28211|Alphaproteobacteria,2K7VF@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
DTH2_k127_9506935_1	926562.Oweho_1032	1.401e-34	145.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2PAQJ@246874|Cryomorphaceae	976|Bacteroidetes	G	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_9506935_0	643867.Ftrac_0657	1.414e-204	648.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
DTH2_k127_9541493_2	468059.AUHA01000002_gene446	2.973e-52	186.0	COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,1IP7G@117747|Sphingobacteriia	976|Bacteroidetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH2_k127_9541493_1	696747.NIES39_Q02170	9.735e-64	244.0	COG1520@1|root,COG1520@2|Bacteria,1GR6J@1117|Cyanobacteria,1HI8I@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5122,PPC,SBBP
DTH2_k127_9541493_4	653733.Selin_2299	1.839e-11	78.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11,F5_F8_type_C
DTH2_k127_9541493_3	1191523.MROS_0519	6.403e-16	92.0	COG4447@1|root,COG5276@1|root,COG4447@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
DTH2_k127_9541493_0	926556.Echvi_1329	7.422e-231	721.0	COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,47JKQ@768503|Cytophagia	976|Bacteroidetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DTH2_k127_95476_2	871968.DESME_04290	9.305e-40	154.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia,2633J@186807|Peptococcaceae	186801|Clostridia	Q	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DTH2_k127_95476_1	945713.IALB_1477	1.405e-53	218.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH2_k127_95476_3	746697.Aeqsu_1982	1.29e-27	132.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,Laminin_G_3,P_proprotein
DTH2_k127_95476_0	1183438.GKIL_2176	1.37e-103	381.0	COG1372@1|root,COG4409@1|root,COG1372@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Phage_Mu_F,RHS_repeat
DTH2_k127_95476_4	525257.HMPREF0204_11809	0.0004929	49.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1INKJ@117743|Flavobacteriia,3ZRYW@59732|Chryseobacterium	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DTH2_k127_9558242_0	269797.Mbar_A1684	7.103e-07	62.0	arCOG02498@1|root,arCOG02526@1|root,arCOG02498@2157|Archaea,arCOG02526@2157|Archaea,2Y0XD@28890|Euryarchaeota	28890|Euryarchaeota	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	NosD
DTH2_k127_9612019_1	1380384.JADN01000003_gene804	1.213e-89	304.0	28HRC@1|root,2Z7YT@2|Bacteria,4NKDD@976|Bacteroidetes,1HYNI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9612019_2	1262449.CP6013_0475	1.198e-87	302.0	COG1835@1|root,COG1835@2|Bacteria,1V7CG@1239|Firmicutes,24WKR@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH2_k127_9612019_0	1268240.ATFI01000013_gene1151	5.13e-160	509.0	COG0667@1|root,COG0667@2|Bacteria,4NFCN@976|Bacteroidetes,2FMAG@200643|Bacteroidia,4AKEC@815|Bacteroidaceae	976|Bacteroidetes	C	Oxidoreductase, aldo keto reductase family protein	gpr	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
DTH2_k127_9612019_3	269797.Mbar_A3547	1.366e-39	157.0	COG0491@1|root,arCOG00504@2157|Archaea,2Y728@28890|Euryarchaeota,2NB5A@224756|Methanomicrobia	224756|Methanomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH2_k127_9684488_7	746697.Aeqsu_0607	1.9e-53	214.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1HYN2@117743|Flavobacteriia	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
DTH2_k127_9684488_9	313606.M23134_05970	6.427e-16	93.0	COG1520@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG4447@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4447@2|Bacteria,4PME7@976|Bacteroidetes,47Y2P@768503|Cytophagia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9684488_10	641526.ADIWIN_0457	7.108e-08	66.0	COG3227@1|root,COG3227@2|Bacteria,4NH5C@976|Bacteroidetes,1I12K@117743|Flavobacteriia	976|Bacteroidetes	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9684488_4	891968.Anamo_1626	1.355e-99	342.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH2_k127_9684488_3	1137281.D778_00505	1.141e-112	373.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia	976|Bacteroidetes	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
DTH2_k127_9684488_6	1121875.KB907547_gene2948	3.073e-64	224.0	COG0251@1|root,COG0251@2|Bacteria,4NMXE@976|Bacteroidetes,1I1GR@117743|Flavobacteriia	976|Bacteroidetes	J	Translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
DTH2_k127_9684488_1	1223410.KN050846_gene2842	1.406e-182	577.0	COG3287@1|root,COG3287@2|Bacteria,4NGTB@976|Bacteroidetes,1HX3X@117743|Flavobacteriia	976|Bacteroidetes	T	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
DTH2_k127_9684488_2	1123277.KB893195_gene5720	5.995e-156	518.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,47U6P@768503|Cytophagia	976|Bacteroidetes	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SnoaL_3
DTH2_k127_9684488_8	1122129.AUEF01000007_gene1889	1.895e-21	100.0	2DMP1@1|root,32SS8@2|Bacteria,1VFZZ@1239|Firmicutes,4HWCC@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
DTH2_k127_9684488_0	1223410.KN050846_gene2836	4.552e-265	861.0	COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3
DTH2_k127_9684488_5	1047013.AQSP01000070_gene34	2.698e-99	346.0	COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,Reg_prop,Y_Y_Y
DTH2_k127_9710652_4	468059.AUHA01000002_gene32	1.974e-33	134.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1IR8V@117747|Sphingobacteriia	976|Bacteroidetes	N	transport system involved in gliding motility, auxiliary component	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DTH2_k127_9710652_2	926562.Oweho_1586	1.019e-87	295.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1HX1M@117743|Flavobacteriia,2PAR7@246874|Cryomorphaceae	976|Bacteroidetes	S	TIGRFAM gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH2_k127_9710652_3	743722.Sph21_2529	1.045e-73	256.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	fjo14	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
DTH2_k127_9710652_1	1197477.IA57_10465	5.908e-120	395.0	COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,1HWPZ@117743|Flavobacteriia	976|Bacteroidetes	T	Phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
DTH2_k127_9710652_0	742817.HMPREF9449_00464	1.409e-147	474.0	COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,2FPKZ@200643|Bacteroidia,22WD6@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DTH2_k127_9713059_0	1122176.KB903543_gene635	2.566e-239	762.0	COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes	976|Bacteroidetes	O	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH2_k127_9715512_0	243233.MCA1586	3.521e-213	691.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1XDIT@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
DTH2_k127_9715512_2	290397.Adeh_3871	1.724e-23	106.0	2DP5T@1|root,330N5@2|Bacteria,1Q5DS@1224|Proteobacteria,43134@68525|delta/epsilon subdivisions,2WX04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
DTH2_k127_9715512_1	1123008.KB905694_gene1726	4.984e-78	264.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH2_k127_9723715_0	929556.Solca_3987	1.478e-117	387.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1INRN@117747|Sphingobacteriia	976|Bacteroidetes	E	alanine dehydrogenase	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH2_k127_9723715_1	714943.Mucpa_6253	1.061e-72	255.0	COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,1IQ2Q@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH2_k127_9728393_0	1408473.JHXO01000004_gene100	2.288e-171	542.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,2FPNE@200643|Bacteroidia	976|Bacteroidetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH2_k127_9728393_1	945713.IALB_2953	3.308e-109	361.0	COG0549@1|root,COG0549@2|Bacteria	2|Bacteria	E	Belongs to the carbamate kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
DTH2_k127_9728393_2	1123400.KB904771_gene3361	4.084e-07	53.0	COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	EamA
DTH2_k127_9732262_0	316067.Geob_2027	2.568e-73	258.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,42SS9@68525|delta/epsilon subdivisions,2WPND@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
DTH2_k127_9732262_1	485913.Krac_4538	6.988e-14	75.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
DTH2_k127_9732352_2	391596.PBAL39_24068	1.848e-32	142.0	COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,1IPAB@117747|Sphingobacteriia	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
DTH2_k127_9732352_0	385682.AFSL01000087_gene717	6.719e-144	464.0	COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,2FKZ9@200643|Bacteroidia,3XJP3@558415|Marinilabiliaceae	976|Bacteroidetes	O	Glycoprotease family	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DTH2_k127_9732352_1	716544.wcw_0565	1.933e-71	253.0	COG0604@1|root,COG0604@2|Bacteria,2JGKF@204428|Chlamydiae	204428|Chlamydiae	C	NADPH quinone reductase and related	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
DTH2_k127_9748225_1	926562.Oweho_2657	8.905e-11	68.0	COG3386@1|root,COG4386@1|root,COG3386@2|Bacteria,COG4386@2|Bacteria,4PP0K@976|Bacteroidetes,1IKDR@117743|Flavobacteriia,2PBMA@246874|Cryomorphaceae	976|Bacteroidetes	G	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH2_k127_9748225_2	745718.JADT01000001_gene1713	1.601e-08	64.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia	976|Bacteroidetes	M	Opacity protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
DTH2_k127_9748225_0	385682.AFSL01000060_gene1779	2.05e-58	208.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,2FMJH@200643|Bacteroidia,3XJ06@558415|Marinilabiliaceae	976|Bacteroidetes	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH2_k127_9754673_3	468059.AUHA01000002_gene248	1.016e-90	302.0	COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,1INYG@117747|Sphingobacteriia	976|Bacteroidetes	IQ	PFAM GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DTH2_k127_9754673_2	1168034.FH5T_03570	1.551e-101	333.0	COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,2FSWC@200643|Bacteroidia	976|Bacteroidetes	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
DTH2_k127_9754673_4	1166018.FAES_3907	9.489e-77	265.0	COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia	976|Bacteroidetes	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DTH2_k127_9754673_7	1121875.KB907551_gene1133	6.999e-36	149.0	COG3087@1|root,COG3087@2|Bacteria,4NF9U@976|Bacteroidetes,1HYQM@117743|Flavobacteriia	976|Bacteroidetes	D	sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DTH2_k127_9754673_5	641143.HMPREF9331_00193	7.419e-71	247.0	COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,1HXZG@117743|Flavobacteriia,1ERAU@1016|Capnocytophaga	976|Bacteroidetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
DTH2_k127_9754673_6	1229487.AMYW01000001_gene3997	2.425e-45	166.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1I2Y7@117743|Flavobacteriia,2NWQV@237|Flavobacterium	976|Bacteroidetes	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
DTH2_k127_9754673_1	484018.BACPLE_03102	1.731e-107	359.0	COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,2FKYK@200643|Bacteroidia,4AK6W@815|Bacteroidaceae	976|Bacteroidetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DTH2_k127_9754673_8	1239962.C943_01085	5.87e-24	103.0	COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,47RA0@768503|Cytophagia	976|Bacteroidetes	O	NifU domain protein	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
DTH2_k127_9754673_0	1454007.JAUG01000018_gene1589	1.42e-153	492.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NEXG@976|Bacteroidetes,1IPN6@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
DTH2_k127_9763721_1	926562.Oweho_1295	1.388e-154	515.0	COG1629@1|root,COG4771@2|Bacteria,4PPAD@976|Bacteroidetes	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
DTH2_k127_9763721_4	869213.JCM21142_41386	6.634e-56	203.0	COG2043@1|root,COG2043@2|Bacteria	2|Bacteria	C	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
DTH2_k127_9763721_5	866536.Belba_2773	5.004e-37	147.0	COG1309@1|root,COG1309@2|Bacteria,4NNNT@976|Bacteroidetes,47SG0@768503|Cytophagia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	qacR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_5,TetR_N
DTH2_k127_9763721_0	1047013.AQSP01000126_gene2741	5.063e-297	925.0	COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
DTH2_k127_9763721_2	709991.Odosp_3644	2.812e-64	224.0	COG3760@1|root,COG3760@2|Bacteria,4NNW9@976|Bacteroidetes,2FSY6@200643|Bacteroidia,22Y37@171551|Porphyromonadaceae	976|Bacteroidetes	S	Aminoacyl-tRNA editing domain	proX	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
DTH2_k127_9763721_3	483216.BACEGG_00034	8.573e-61	213.0	COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia,4AMZC@815|Bacteroidaceae	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH2_k127_9782396_2	709991.Odosp_0507	3.739e-127	411.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,2FNNC@200643|Bacteroidia,22WEU@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
DTH2_k127_9782396_7	406818.XBJ1_3704	9.34e-06	48.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9782396_3	1443665.JACA01000056_gene3245	5.147e-111	367.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1HX06@117743|Flavobacteriia,2YGVT@290174|Aquimarina	976|Bacteroidetes	S	Ethanolamine utilisation - propanediol utilisation	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
DTH2_k127_9782396_0	926562.Oweho_2840	5.789e-192	607.0	COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,1HXD2@117743|Flavobacteriia,2PAKT@246874|Cryomorphaceae	976|Bacteroidetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
DTH2_k127_9782396_5	1168289.AJKI01000031_gene972	4.779e-32	129.0	COG1188@1|root,COG1188@2|Bacteria,4NP8I@976|Bacteroidetes,2FRYM@200643|Bacteroidia,3XK4R@558415|Marinilabiliaceae	976|Bacteroidetes	J	S4 RNA-binding domain	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
DTH2_k127_9782396_4	1453500.AT05_01950	5.084e-80	278.0	COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HX79@117743|Flavobacteriia	976|Bacteroidetes	S	Endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9782396_6	153721.MYP_3679	3.089e-11	70.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
DTH2_k127_9782396_1	1237149.C900_01785	9.349e-181	574.0	COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia	976|Bacteroidetes	F	TIGRFAM dihydroorotase, multifunctional complex type	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH2_k127_9791250_1	880073.Calab_1356	9.54e-162	525.0	COG1305@1|root,COG1305@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
DTH2_k127_9791250_0	1168034.FH5T_10475	1.411e-172	577.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,2G2V9@200643|Bacteroidia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,TPR_12,TPR_8,Y_Y_Y
DTH2_k127_9791250_2	1168034.FH5T_10480	1.155e-76	264.0	COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,2FUZW@200643|Bacteroidia	976|Bacteroidetes	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
DTH2_k127_9791250_3	1313301.AUGC01000008_gene444	2.026e-76	289.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NF8H@976|Bacteroidetes	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Inhibitor_I69,MAM,Peptidase_C10,Peptidase_M14,Peptidase_M43,Reprolysin_4,fn3
DTH2_k127_9791250_4	143224.JQMD01000002_gene2762	1.613e-73	280.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,1HYIK@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
DTH2_k127_9791250_5	391603.FBALC1_12732	3.674e-05	55.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Peptidase_M43,Reprolysin_4
DTH2_k127_981058_0	1121904.ARBP01000001_gene5520	2.03e-95	326.0	COG0644@1|root,COG0644@2|Bacteria,4NKR8@976|Bacteroidetes	976|Bacteroidetes	C	TIGRFAM geranylgeranyl reductase family	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
DTH2_k127_981058_1	694427.Palpr_2877	2.187e-17	93.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,2FPV4@200643|Bacteroidia,22WRT@171551|Porphyromonadaceae	976|Bacteroidetes	T	Belongs to the universal stress protein A family	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
DTH2_k127_9813797_0	1168034.FH5T_03450	5.536e-257	799.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DTH2_k127_9813797_12	929562.Emtol_4017	5.261e-33	146.0	28KQM@1|root,2ZA8D@2|Bacteria,4NG3K@976|Bacteroidetes,47XIW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9813797_7	927658.AJUM01000022_gene992	1.263e-45	176.0	COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,2FNB5@200643|Bacteroidia,3XJW0@558415|Marinilabiliaceae	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
DTH2_k127_9813797_4	926549.KI421517_gene2052	2.37e-102	337.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47KDU@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH2_k127_9813797_5	1131812.JQMS01000001_gene3202	1.919e-71	246.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,1HX1J@117743|Flavobacteriia,2NSMS@237|Flavobacterium	976|Bacteroidetes	S	Cob(I)yrinic acid a c-diamide adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
DTH2_k127_9813797_11	1268240.ATFI01000001_gene3775	3.047e-37	140.0	2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,2FTSK@200643|Bacteroidia,4ARQ3@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2795
DTH2_k127_9813797_6	1433126.BN938_2890	9.719e-54	194.0	COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,2FSR0@200643|Bacteroidia,22UE7@171550|Rikenellaceae	976|Bacteroidetes	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
DTH2_k127_9813797_13	761193.Runsl_3777	8.138e-20	100.0	29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,47PSA@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3822)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3822
DTH2_k127_9813797_10	385682.AFSL01000003_gene1928	3.143e-39	154.0	2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,3XIJG@558415|Marinilabiliaceae	976|Bacteroidetes	S	COG NOG19144 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9813797_8	945713.IALB_0238	1.432e-45	166.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
DTH2_k127_9813797_9	1296416.JACB01000064_gene5025	5.477e-45	168.0	COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia,2YJ86@290174|Aquimarina	976|Bacteroidetes	V	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
DTH2_k127_9813797_1	700598.Niako_5038	6.339e-132	424.0	COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_9813797_3	1408473.JHXO01000006_gene1153	1.184e-113	375.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,2FNY6@200643|Bacteroidia	976|Bacteroidetes	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DTH2_k127_9813797_2	1453500.AT05_04630	4.108e-126	411.0	COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1HXQU@117743|Flavobacteriia	976|Bacteroidetes	I	AMP-dependent synthetase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DTH2_k127_9826135_2	1120951.AUBG01000016_gene3618	2.75e-77	284.0	2DBCT@1|root,2Z8FK@2|Bacteria,4PKQY@976|Bacteroidetes,1HYK1@117743|Flavobacteriia	976|Bacteroidetes	S	Peptide-N-glycosidase F, N terminal	-	-	-	-	-	-	-	-	-	-	-	-	N-glycanase_C,N-glycanase_N
DTH2_k127_9826135_5	761193.Runsl_2876	8.487e-13	82.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,4NF7B@976|Bacteroidetes,47MQS@768503|Cytophagia	976|Bacteroidetes	G	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,PKD
DTH2_k127_9826135_3	926562.Oweho_2256	1.335e-31	143.0	COG3291@1|root,COG5306@1|root,COG3291@2|Bacteria,COG5306@2|Bacteria,4PP0T@976|Bacteroidetes,1IKE2@117743|Flavobacteriia,2PBMC@246874|Cryomorphaceae	976|Bacteroidetes	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9826135_1	525373.HMPREF0766_10278	2.286e-79	286.0	COG4198@1|root,COG4198@2|Bacteria,4P1AT@976|Bacteroidetes,1IUW6@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
DTH2_k127_9826135_0	525373.HMPREF0766_10277	8.626e-273	875.0	COG1629@1|root,COG4771@2|Bacteria,4P0X2@976|Bacteroidetes,1IVJ0@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_9826135_4	1047013.AQSP01000139_gene2339	1.007e-26	112.0	COG2836@1|root,COG2836@2|Bacteria	2|Bacteria	K	Biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
DTH2_k127_9836476_1	909663.KI867150_gene1546	0.0008282	42.0	2EQZT@1|root,33IJD@2|Bacteria,1NKTX@1224|Proteobacteria,42XNG@68525|delta/epsilon subdivisions,2WTCK@28221|Deltaproteobacteria,2MQPM@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9836476_0	880073.Calab_0005	8.943e-152	492.0	COG0317@1|root,COG0317@2|Bacteria,2NNM0@2323|unclassified Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
DTH2_k127_9836772_4	1123234.AUKI01000020_gene763	2.755e-40	155.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1HXBN@117743|Flavobacteriia	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DTH2_k127_9836772_3	1121870.AUAA01000008_gene477	3.406e-46	174.0	COG0572@1|root,COG0572@2|Bacteria,4P0RC@976|Bacteroidetes,1I7D7@117743|Flavobacteriia	976|Bacteroidetes	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
DTH2_k127_9836772_1	1047013.AQSP01000130_gene1859	4.93e-158	509.0	COG0438@1|root,COG0438@2|Bacteria,2NQFS@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	sps	GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576	2.4.1.14,2.4.1.246	ko:K00696,ko:K13058	ko00500,ko01100,map00500,map01100	-	R00766,R08947	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
DTH2_k127_9836772_2	385682.AFSL01000063_gene1544	3.953e-61	219.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,2FQHX@200643|Bacteroidia,3XJK7@558415|Marinilabiliaceae	976|Bacteroidetes	S	Uncharacterized protein family UPF0029	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
DTH2_k127_9836772_0	1168034.FH5T_00005	1.903e-198	630.0	COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,2FNPD@200643|Bacteroidia	976|Bacteroidetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DTH2_k127_9849767_0	1168289.AJKI01000014_gene2087	2.875e-289	915.0	COG1523@1|root,COG1523@2|Bacteria,4NHA4@976|Bacteroidetes,2G0D6@200643|Bacteroidia,3XIMN@558415|Marinilabiliaceae	976|Bacteroidetes	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48,FlgD_ig
DTH2_k127_9849767_2	1122179.KB890422_gene2197	2.967e-27	124.0	COG2374@1|root,COG2374@2|Bacteria,4NI5S@976|Bacteroidetes	976|Bacteroidetes	G	6-phosphogluconolactonase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_5,Calx-beta,Exo_endo_phos,He_PIG,LTD,VCBS
DTH2_k127_9849767_1	945713.IALB_0843	1.488e-28	131.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
DTH2_k127_9854337_1	756272.Plabr_1309	1.674e-56	205.0	COG1216@1|root,COG1216@2|Bacteria,2J51B@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_9854337_2	562970.Btus_3140	4.949e-14	78.0	COG2456@1|root,COG2456@2|Bacteria,1UPVP@1239|Firmicutes,4HNQC@91061|Bacilli,27A7Y@186823|Alicyclobacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
DTH2_k127_9854337_0	589865.DaAHT2_0369	1.902e-67	234.0	COG0463@1|root,COG2456@1|root,COG0463@2|Bacteria,COG2456@2|Bacteria,1QW3P@1224|Proteobacteria,42QT7@68525|delta/epsilon subdivisions,2X8CG@28221|Deltaproteobacteria,2MPMX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_9857258_4	1150600.ADIARSV_1900	0.0003852	45.0	COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia	976|Bacteroidetes	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
DTH2_k127_9857258_1	1121875.KB907547_gene3347	3.506e-88	298.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia	976|Bacteroidetes	S	UDP-2,3-diacylglucosamine hydrolase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
DTH2_k127_9857258_2	1550091.JROE01000004_gene1699	5.814e-12	78.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1INSA@117747|Sphingobacteriia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
DTH2_k127_9857258_3	1434325.AZQN01000002_gene1065	4.838e-07	58.0	2CH9X@1|root,32ZWK@2|Bacteria,4NXAQ@976|Bacteroidetes,47SB9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9857258_0	694427.Palpr_2188	2.458e-95	319.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,22X9V@171551|Porphyromonadaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH2_k127_9903193_3	1392488.JHZY01000004_gene3010	3.212e-46	171.0	COG0350@1|root,COG0350@2|Bacteria,4NFYC@976|Bacteroidetes,1I29J@117743|Flavobacteriia,2XJA4@283735|Leeuwenhoekiella	976|Bacteroidetes	L	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DTH2_k127_9903193_0	880073.Calab_1714	2.166e-198	634.0	COG2866@1|root,COG2866@2|Bacteria,2NQT6@2323|unclassified Bacteria	2|Bacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DTH2_k127_9903193_1	886379.AEWI01000014_gene1483	1.684e-152	488.0	COG0205@1|root,COG0205@2|Bacteria,4NGN7@976|Bacteroidetes,2FNIF@200643|Bacteroidia,3XJ0I@558415|Marinilabiliaceae	976|Bacteroidetes	G	Phosphofructokinase	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DTH2_k127_9903193_4	1499967.BAYZ01000061_gene5977	5.223e-10	67.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,PAS_9,Reg_prop,Response_reg,Y_Y_Y
DTH2_k127_9903193_2	1239962.C943_00480	1.126e-93	312.0	COG0300@1|root,COG0300@2|Bacteria,4NEKV@976|Bacteroidetes,47NJG@768503|Cytophagia	976|Bacteroidetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH2_k127_9906904_0	869213.JCM21142_517	9.038e-199	631.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH2_k127_9906904_1	762903.Pedsa_1125	4.715e-58	205.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH2_k127_9918171_0	497964.CfE428DRAFT_1137	0.0	1011.0	COG0282@1|root,COG4869@1|root,COG0282@2|Bacteria,COG4869@2|Bacteria,46SKB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC,cNMP_binding
DTH2_k127_9918171_1	1492737.FEM08_01180	1.273e-230	720.0	COG0281@1|root,COG0281@2|Bacteria,4PBZC@976|Bacteroidetes,1IMVT@117743|Flavobacteriia,2NVDF@237|Flavobacterium	976|Bacteroidetes	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
DTH2_k127_9954491_0	1408473.JHXO01000008_gene2798	6.062e-137	446.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DTH2_k127_9954491_2	1408473.JHXO01000008_gene2794	1.859e-58	218.0	28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,2FQ8C@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4249
DTH2_k127_9954491_1	1408473.JHXO01000008_gene2792	3.457e-66	246.0	COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,2G2ZM@200643|Bacteroidia	976|Bacteroidetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH2_k127_9955944_0	385682.AFSL01000069_gene1447	1.009e-318	985.0	COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,2FPG7@200643|Bacteroidia,3XIY4@558415|Marinilabiliaceae	976|Bacteroidetes	L	TopoisomeraseII	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH2_k127_9962498_2	1121889.AUDM01000003_gene2259	9.467e-94	311.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,1HZHQ@117743|Flavobacteriia,2NVH2@237|Flavobacterium	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH2_k127_9962498_1	760192.Halhy_6511	4.155e-151	497.0	COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes,1IUX1@117747|Sphingobacteriia	976|Bacteroidetes	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH2_k127_9962498_0	927658.AJUM01000037_gene2330	5.636e-171	541.0	COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,3XIQ0@558415|Marinilabiliaceae	976|Bacteroidetes	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH2_k127_9963728_1	1121129.KB903359_gene1354	5.008e-80	272.0	COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,2FM94@200643|Bacteroidia,22XNT@171551|Porphyromonadaceae	976|Bacteroidetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
DTH2_k127_9963728_0	468059.AUHA01000003_gene1985	4.776e-103	359.0	COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,1IP53@117747|Sphingobacteriia	976|Bacteroidetes	M	PFAM sulfatase	ltaS2	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH2_k127_9963728_2	1280692.AUJL01000009_gene2932	8.344e-12	67.0	COG2345@1|root,COG2345@2|Bacteria,1VKUB@1239|Firmicutes,24UW4@186801|Clostridia,36N4R@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11
DTH2_k127_997015_0	1121373.KB903664_gene2654	2.993e-254	789.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47MT5@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
## 3048 queries scanned
## Total time (seconds): 49.952136516571045
## Rate: 61.02 q/s