## Tue Oct 15 18:11:18 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/DTH3_bin.17.fa -m mmseqs --itype genome -o DTH3_bin.17 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/DTH3_bin.17 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DTH3_k127_1000854_2	1340493.JNIF01000003_gene1731	1.835e-91	308.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH3_k127_1000854_0	1403819.BATR01000092_gene2754	1.43e-131	431.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
DTH3_k127_1000854_3	86106.I862_01655	7.955e-10	69.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,47F1D@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DTH3_k127_1000854_1	1267534.KB906754_gene3770	5.456e-102	340.0	COG1007@1|root,COG1007@2|Bacteria,3Y73U@57723|Acidobacteria,2JMM8@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH3_k127_1023944_2	42099.EPrPV00000023594	1.501e-53	190.0	COG0590@1|root,KOG1018@2759|Eukaryota	2759|Eukaryota	FJ	deaminase activity	FCY1	GO:0003674,GO:0003824,GO:0004131,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009451,GO:0009987,GO:0016070,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019858,GO:0034641,GO:0034654,GO:0043094,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046087,GO:0046131,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
DTH3_k127_1023944_7	1403819.BATR01000031_gene994	6.007e-07	57.0	2EMM1@1|root,33F9E@2|Bacteria,46TBT@74201|Verrucomicrobia,2IUX2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1023944_0	1396418.BATQ01000019_gene5009	5.382e-160	515.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH3_k127_1023944_1	671143.DAMO_2922	4.327e-72	257.0	COG1562@1|root,COG1562@2|Bacteria,2NQ18@2323|unclassified Bacteria	2|Bacteria	I	Squalene/phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99	ko:K00801,ko:K02291,ko:K10208	ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130	M00097	R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177	RC00362,RC00796,RC01101,RC02839,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
DTH3_k127_1023944_5	443143.GM18_2349	2.551e-18	89.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,42TER@68525|delta/epsilon subdivisions,2WPKW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
DTH3_k127_1023944_4	388467.A19Y_4225	4.682e-26	108.0	2CIXY@1|root,338DR@2|Bacteria,1G934@1117|Cyanobacteria,1HDGE@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1023944_3	933262.AXAM01000130_gene757	1.13e-26	111.0	COG1598@1|root,COG1598@2|Bacteria,1P1K3@1224|Proteobacteria,431VD@68525|delta/epsilon subdivisions,2WWWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1023944_6	278957.ABEA03000215_gene4275	3.419e-14	74.0	COG0165@1|root,COG0165@2|Bacteria,46UYU@74201|Verrucomicrobia,3K76F@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
DTH3_k127_1029663_3	1408311.JNJM01000027_gene2789	0.0005673	46.0	COG1396@1|root,COG3947@1|root,COG1396@2|Bacteria,COG3947@2|Bacteria,1VBQT@1239|Firmicutes,24NQ1@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Response_reg
DTH3_k127_1029663_1	595460.RRSWK_04460	4.065e-69	254.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH3_k127_1029663_0	497964.CfE428DRAFT_5953	2.313e-120	408.0	COG0642@1|root,COG2205@2|Bacteria,46Z6V@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DTH3_k127_1029663_2	1123373.ATXI01000004_gene1419	6.729e-05	48.0	COG2204@1|root,COG2204@2|Bacteria,2GHIR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_106616_0	748247.AZKH_2522	2.246e-126	407.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJFI@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DTH3_k127_106616_2	1403819.BATR01000047_gene1361	1.391e-36	145.0	COG3224@1|root,COG3224@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
DTH3_k127_106616_1	1396418.BATQ01000182_gene902	2.144e-113	370.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH3_k127_106616_3	1123360.thalar_02413	5.527e-13	68.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH3_k127_1085293_1	84531.JMTZ01000052_gene1595	2.639e-92	308.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1X3YD@135614|Xanthomonadales	135614|Xanthomonadales	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DTH3_k127_1085293_3	1123073.KB899243_gene738	3.292e-60	217.0	COG1392@1|root,COG1392@2|Bacteria,1PKQF@1224|Proteobacteria,1SMFE@1236|Gammaproteobacteria,1X412@135614|Xanthomonadales	135614|Xanthomonadales	P	Pit accessory protein	VL23_21310	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DTH3_k127_1085293_0	1123242.JH636435_gene3064	8.859e-109	368.0	COG0477@1|root,COG0477@2|Bacteria,2IX7U@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
DTH3_k127_1085293_2	497964.CfE428DRAFT_0621	3.661e-79	271.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH3_k127_1099599_3	595460.RRSWK_03258	1.721e-29	121.0	COG0153@1|root,COG0153@2|Bacteria,2IZT3@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the GHMP kinase family. GalK subfamily	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
DTH3_k127_1099599_0	661478.OP10G_1601	1.348e-147	474.0	COG1085@1|root,COG1085@2|Bacteria	2|Bacteria	C	galactose-1-phosphate uridylyltransferase	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
DTH3_k127_1099599_2	926550.CLDAP_06140	1.458e-30	126.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH3_k127_1099599_1	742766.HMPREF9455_03994	5.281e-97	331.0	COG5434@1|root,COG5434@2|Bacteria,4NDWX@976|Bacteroidetes,2FMZA@200643|Bacteroidia,22X8E@171551|Porphyromonadaceae	976|Bacteroidetes	M	Parallel beta-helix repeats	glaB	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH3_k127_1115096_1	452637.Oter_2144	3.601e-22	99.0	COG5074@1|root,COG5074@2|Bacteria,46W5A@74201|Verrucomicrobia,3K8CX@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1115096_0	357808.RoseRS_3616	1.883e-110	374.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
DTH3_k127_1117276_1	1303518.CCALI_00532	1.748e-160	515.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
DTH3_k127_1117276_0	886293.Sinac_5668	1.876e-219	688.0	COG2115@1|root,COG2115@2|Bacteria,2IWUS@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_1117276_2	497964.CfE428DRAFT_0773	2.577e-100	336.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH3_k127_1117276_4	86416.Clopa_2098	3.722e-24	110.0	2A1FW@1|root,30PPA@2|Bacteria,1UA53@1239|Firmicutes,254CY@186801|Clostridia,36TYS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1117276_5	497964.CfE428DRAFT_0773	4.352e-14	74.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH3_k127_1117276_3	929562.Emtol_1793	3.232e-56	199.0	COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,47MQT@768503|Cytophagia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	aldH	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
DTH3_k127_1121557_2	1396141.BATP01000044_gene1489	1.32e-62	217.0	COG1012@1|root,COG1012@2|Bacteria,46TX0@74201|Verrucomicrobia,2IUT7@203494|Verrucomicrobiae	2|Bacteria	C	Aldehyde dehydrogenase family	aldA	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_1121557_0	1396141.BATP01000030_gene3706	3.069e-94	344.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,46UHX@74201|Verrucomicrobia,2IVRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH3_k127_1121557_1	1396141.BATP01000030_gene3705	2.143e-79	273.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_1121557_3	1408433.JHXV01000007_gene2956	4.239e-07	52.0	COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,1HXF6@117743|Flavobacteriia,2PAPJ@246874|Cryomorphaceae	976|Bacteroidetes	S	Serine aminopeptidase, S33	ybfF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH3_k127_1121960_1	370438.PTH_0469	3.87e-82	287.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
DTH3_k127_1121960_0	368408.Tpen_1559	4.575e-144	474.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1156121_1	1255043.TVNIR_1306	9.178e-24	102.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
DTH3_k127_1156121_0	452637.Oter_2954	0.0	1243.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1156121_2	935839.JAGJ01000024_gene2469	8.772e-10	71.0	COG0737@1|root,COG3250@1|root,COG3934@1|root,COG4409@1|root,COG0737@2|Bacteria,COG3250@2|Bacteria,COG3934@2|Bacteria,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,DUF4091,F5_F8_type_C,NPCBM,NPCBM_assoc
DTH3_k127_1166134_1	945713.IALB_2577	3.247e-77	295.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,HYR,LTD,P_proprotein
DTH3_k127_1166134_3	583355.Caka_1736	1.069e-19	106.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_1166134_2	273068.TTE1388	1.41e-26	110.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DTH3_k127_1166134_0	497964.CfE428DRAFT_3556	4.799e-286	895.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DTH3_k127_1166835_1	1254432.SCE1572_17230	2.54e-55	207.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH3_k127_1166835_0	1379698.RBG1_1C00001G1725	2.295e-160	531.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
DTH3_k127_1185187_1	497964.CfE428DRAFT_4660	1.539e-31	124.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_1185187_2	293613.A1E_02110	1.825e-11	74.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,47EYI@766|Rickettsiales	766|Rickettsiales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_1185187_0	700598.Niako_1749	6.094e-61	219.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
DTH3_k127_1185187_3	344747.PM8797T_25596	2.527e-08	63.0	COG3137@1|root,COG3137@2|Bacteria,2J024@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
DTH3_k127_1188881_1	452637.Oter_2430	5.422e-19	86.0	COG0175@1|root,COG0175@2|Bacteria,46TUQ@74201|Verrucomicrobia,3K7NR@414999|Opitutae	74201|Verrucomicrobia	H	PFAM phosphoadenosine phosphosulfate reductase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH3_k127_1188881_0	497964.CfE428DRAFT_4587	3.047e-232	725.0	COG2895@1|root,COG2895@2|Bacteria,46SN4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
DTH3_k127_1197576_0	909663.KI867150_gene1090	2.507e-311	958.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
DTH3_k127_1197576_1	909663.KI867150_gene1089	8.847e-273	845.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH3_k127_1197576_7	909663.KI867150_gene1088	7.386e-91	304.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
DTH3_k127_1197576_12	296591.Bpro_3359	4.459e-33	133.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
DTH3_k127_1197576_10	1123368.AUIS01000029_gene1290	1.539e-49	183.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
DTH3_k127_1197576_14	1121939.L861_16535	2.945e-10	62.0	COG2331@1|root,COG2331@2|Bacteria,1NMRY@1224|Proteobacteria	1224|Proteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH3_k127_1197576_15	880073.Calab_3105	6.101e-07	62.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
DTH3_k127_1197576_8	234267.Acid_1882	7.881e-78	268.0	2DF1J@1|root,2ZQ4G@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH3_k127_1197576_6	234267.Acid_1881	1.072e-115	379.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_1197576_2	880073.Calab_3105	1.741e-229	726.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
DTH3_k127_1197576_9	28072.Nos7524_1372	4.693e-64	252.0	COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G1WI@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin,Calx-beta,PPC
DTH3_k127_1197576_16	1121887.AUDK01000004_gene431	6.105e-06	61.0	COG2911@1|root,COG3210@1|root,COG3533@1|root,COG4625@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,4PPKP@976|Bacteroidetes,1IKQ3@117743|Flavobacteriia,2P0T3@237|Flavobacterium	976|Bacteroidetes	U	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Laminin_G_3
DTH3_k127_1197576_5	278963.ATWD01000002_gene473	1.079e-121	402.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	mdsC	-	2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
DTH3_k127_1197576_3	452637.Oter_0886	8.855e-139	449.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DTH3_k127_1197576_11	118005.AWNK01000005_gene1565	2.476e-46	177.0	COG0290@1|root,COG0290@2|Bacteria	2|Bacteria	J	translation initiation factor activity	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DTH3_k127_1197576_4	452637.Oter_0604	7.764e-124	403.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,3K7QK@414999|Opitutae	414999|Opitutae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DTH3_k127_1205204_2	661478.OP10G_4802	1.044e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_1205204_0	886293.Sinac_6957	0.0	1209.0	COG2010@1|root,COG2010@2|Bacteria,2J2GM@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_1205204_3	504487.JCM19302_1724	1.174e-07	59.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
DTH3_k127_1205204_1	886293.Sinac_6958	8.475e-156	496.0	COG1524@1|root,COG1524@2|Bacteria,2J563@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_1207972_1	1396418.BATQ01000171_gene2984	6.302e-30	121.0	COG4977@1|root,COG4977@2|Bacteria,46Z4W@74201|Verrucomicrobia,2IWPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
DTH3_k127_1207972_0	1121333.JMLH01000013_gene2531	5.538e-177	575.0	COG1196@1|root,COG2911@1|root,COG3250@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	CP_0954	-	3.2.1.23,3.2.1.97,4.2.2.1	ko:K01190,ko:K01727,ko:K17624	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH101,PL8	-	5_nucleotid,DUF2804,DctA-YdbH
DTH3_k127_1208635_0	497964.CfE428DRAFT_3481	1.06e-180	585.0	COG0443@1|root,COG0443@2|Bacteria,46TYN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
DTH3_k127_1208635_3	452637.Oter_0619	5.169e-66	237.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	VVA1313	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DTH3_k127_1208635_5	481448.Minf_1524	2.122e-34	141.0	COG0452@1|root,COG0452@2|Bacteria,46WUX@74201|Verrucomicrobia,37GRH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	DNA / pantothenate metabolism flavoprotein	-	-	6.3.2.5	ko:K21977	ko00770,map00770	M00120	R04231	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP
DTH3_k127_1208635_1	278957.ABEA03000085_gene2554	1.052e-108	359.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
DTH3_k127_1208635_4	335543.Sfum_2639	2.015e-59	227.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MQVW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DTH3_k127_1208635_6	880073.Calab_0824	6.553e-29	123.0	COG0295@1|root,COG0295@2|Bacteria,2NPJN@2323|unclassified Bacteria	2|Bacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_2618	dCMP_cyt_deam_1,dCMP_cyt_deam_2
DTH3_k127_1208635_2	720555.BATR1942_10025	1.394e-68	241.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DTH3_k127_1223011_5	497964.CfE428DRAFT_4941	2.012e-22	101.0	2E5PI@1|root,330E7@2|Bacteria,46W49@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1223011_1	497964.CfE428DRAFT_4940	7.955e-137	440.0	COG1099@1|root,COG1099@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
DTH3_k127_1223011_2	452637.Oter_1808	6.728e-84	290.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
DTH3_k127_1223011_3	452637.Oter_1864	3.602e-54	199.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
DTH3_k127_1223011_4	452637.Oter_2367	1.276e-35	143.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1223011_0	497964.CfE428DRAFT_0348	7.995e-237	760.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DTH3_k127_1223011_6	1128421.JAGA01000003_gene3515	1.434e-17	87.0	COG4911@1|root,COG4911@2|Bacteria,2NQ4H@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
DTH3_k127_1223185_1	497964.CfE428DRAFT_5894	7.13e-105	345.0	COG3119@1|root,COG3119@2|Bacteria,46U45@74201|Verrucomicrobia	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_1223185_0	1123242.JH636435_gene1197	1.704e-201	638.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH3_k127_1227615_0	1396141.BATP01000040_gene2102	2.082e-127	423.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_1227615_1	1396141.BATP01000032_gene4347	5.513e-67	237.0	COG0386@1|root,COG0386@2|Bacteria,46V2M@74201|Verrucomicrobia,2IUDT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	GSHPx
DTH3_k127_1227615_2	935845.JADQ01000068_gene1505	1.197e-22	102.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
DTH3_k127_1228538_0	452637.Oter_3022	1.165e-67	237.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,46U8V@74201|Verrucomicrobia,3K7U6@414999|Opitutae	414999|Opitutae	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
DTH3_k127_1228538_1	1121324.CLIT_23c01830	1.86e-40	158.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH3_k127_1228538_2	1210884.HG799467_gene13206	4.88e-25	106.0	COG0205@1|root,COG0205@2|Bacteria,2IXXF@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DTH3_k127_1234141_0	382464.ABSI01000005_gene1011	7.541e-107	356.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,2IVDM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
DTH3_k127_1234141_2	497964.CfE428DRAFT_6409	9.454e-11	68.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
DTH3_k127_1234141_1	497964.CfE428DRAFT_6409	8.798e-99	345.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
DTH3_k127_1234141_3	96561.Dole_2050	2.685e-10	64.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
DTH3_k127_1255294_0	497964.CfE428DRAFT_6439	1.048e-143	459.0	COG0413@1|root,COG0413@2|Bacteria	2|Bacteria	H	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	-	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
DTH3_k127_1255294_1	497964.CfE428DRAFT_1804	1.91e-131	457.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH3_k127_1255838_4	1489678.RDMS_00910	5.855e-17	86.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
DTH3_k127_1255838_5	522373.Smlt1323	2.457e-11	74.0	COG3335@1|root,COG3335@2|Bacteria,1MW8A@1224|Proteobacteria,1RY10@1236|Gammaproteobacteria,1X3VX@135614|Xanthomonadales	135614|Xanthomonadales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
DTH3_k127_1255838_3	1122604.JONR01000006_gene2730	4.354e-53	193.0	COG0494@1|root,COG0494@2|Bacteria,1RI3B@1224|Proteobacteria,1S6HR@1236|Gammaproteobacteria,1X60F@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA mismatch repair protein MutT	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
DTH3_k127_1255838_1	583355.Caka_1932	1.16e-99	338.0	COG4398@1|root,COG4398@2|Bacteria,46SM5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
DTH3_k127_1255838_0	497964.CfE428DRAFT_2417	7.343e-162	517.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
DTH3_k127_1255838_2	1396141.BATP01000006_gene5486	3.635e-62	216.0	2DHFW@1|root,2ZZKM@2|Bacteria,46SNY@74201|Verrucomicrobia,2IVW8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1264031_2	1395587.P364_0100735	3.09e-31	136.0	COG1409@1|root,COG1409@2|Bacteria,1V574@1239|Firmicutes,4HW52@91061|Bacilli,26S57@186822|Paenibacillaceae	91061|Bacilli	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH3_k127_1264031_1	481448.Minf_0292	3.843e-59	216.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,37G1D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
DTH3_k127_1264031_0	316067.Geob_0443	1.269e-76	269.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,43SZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
DTH3_k127_1268108_0	1123070.KB899248_gene182	1.309e-81	274.0	COG0377@1|root,COG0377@2|Bacteria,46SMM@74201|Verrucomicrobia,2ITJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH3_k127_1268108_1	1396418.BATQ01000167_gene1768	1.99e-13	74.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH3_k127_1269217_2	1396418.BATQ01000139_gene3250	7.732e-25	105.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,2ITI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
DTH3_k127_1269217_1	452637.Oter_4633	5.125e-72	261.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,3K73Q@414999|Opitutae	414999|Opitutae	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
DTH3_k127_1269217_0	497964.CfE428DRAFT_4831	1.5e-169	546.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
DTH3_k127_1270190_1	382464.ABSI01000010_gene3622	1.11e-197	633.0	COG0551@1|root,COG0551@2|Bacteria,46SJD@74201|Verrucomicrobia,2IVAK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
DTH3_k127_1270190_2	382464.ABSI01000010_gene3621	1.047e-191	608.0	COG2960@1|root,COG2960@2|Bacteria,46UCE@74201|Verrucomicrobia,2IVAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
DTH3_k127_1270190_3	935863.AWZR01000001_gene1970	2.697e-137	445.0	COG2382@1|root,COG2382@2|Bacteria,1NFUS@1224|Proteobacteria,1T816@1236|Gammaproteobacteria,1XA10@135614|Xanthomonadales	135614|Xanthomonadales	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
DTH3_k127_1270190_6	497964.CfE428DRAFT_3172	1.796e-44	166.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yitI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DTH3_k127_1270190_9	794903.OPIT5_14770	5.609e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_1270190_5	298654.FraEuI1c_4826	3.669e-62	233.0	COG2234@1|root,COG2234@2|Bacteria,2GJ67@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH3_k127_1270190_7	497964.CfE428DRAFT_3867	4.414e-42	156.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
DTH3_k127_1270190_0	330214.NIDE3482	7.66e-220	687.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
DTH3_k127_1270190_4	589865.DaAHT2_0221	9.396e-92	314.0	COG2172@1|root,COG2208@1|root,COG5002@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,1PGCN@1224|Proteobacteria,42ZJ2@68525|delta/epsilon subdivisions,2WUYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
DTH3_k127_1278286_1	278957.ABEA03000097_gene778	6.315e-77	275.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,3K7TC@414999|Opitutae	414999|Opitutae	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DTH3_k127_1278286_3	481448.Minf_1981	3.938e-09	64.0	COG1544@1|root,COG1544@2|Bacteria,46WSI@74201|Verrucomicrobia,37HA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
DTH3_k127_1278286_0	497964.CfE428DRAFT_2596	9.64e-90	311.0	COG0402@1|root,COG0402@2|Bacteria,46TB5@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH3_k127_1278286_2	1396141.BATP01000003_gene4885	4.25e-56	203.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia,2ITJB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Aminotransferase class I and II	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH3_k127_1278472_1	1118054.CAGW01000058_gene2063	6.681e-09	61.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,26RX8@186822|Paenibacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH3_k127_1278472_0	886293.Sinac_2497	6.462e-74	281.0	COG1595@1|root,COG2373@1|root,COG1595@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K03088,ko:K06894	-	-	-	-	ko00000,ko03021	-	-	-	A2M_N,CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
DTH3_k127_1287719_0	864051.BurJ1DRAFT_3700	1.986e-209	721.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
DTH3_k127_1287719_1	497964.CfE428DRAFT_2621	3.562e-165	529.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
DTH3_k127_1287719_2	497964.CfE428DRAFT_2620	6.779e-118	385.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH3_k127_1291150_3	278957.ABEA03000021_gene1723	7.691e-31	133.0	COG1361@1|root,COG1361@2|Bacteria,46XYW@74201|Verrucomicrobia,3K8N4@414999|Opitutae	414999|Opitutae	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DTH3_k127_1291150_1	452637.Oter_1700	5.138e-66	231.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_1291150_2	118166.JH976538_gene5065	1.567e-65	246.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
DTH3_k127_1291150_4	1396141.BATP01000004_gene5925	1.544e-27	122.0	COG3250@1|root,COG4692@1|root,COG3250@2|Bacteria,COG4692@2|Bacteria,46Z9T@74201|Verrucomicrobia,2IWDF@203494|Verrucomicrobiae	2|Bacteria	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
DTH3_k127_1291150_5	1211813.CAPH01000009_gene63	0.0009163	43.0	COG4692@1|root,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2,Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH3_k127_1291150_0	1122931.AUAE01000006_gene3124	1.764e-80	282.0	COG0639@1|root,COG0639@2|Bacteria,4NZWK@976|Bacteroidetes,2FPXD@200643|Bacteroidia	976|Bacteroidetes	T	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_1297837_1	1403819.BATR01000045_gene1324	2.787e-52	189.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DTH3_k127_1297837_2	316274.Haur_3256	8.179e-24	112.0	2DQAK@1|root,335NK@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4919)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4919
DTH3_k127_1297837_0	589865.DaAHT2_2132	2.462e-104	349.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DTH3_k127_1297837_3	530564.Psta_1650	7.162e-15	78.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_1297837_4	96561.Dole_0778	0.0003863	53.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2MI01@213118|Desulfobacterales	28221|Deltaproteobacteria	S	metal-dependent phosphohydrolase 7TM intracellular region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
DTH3_k127_1302749_0	1396141.BATP01000030_gene3719	4.083e-217	706.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
DTH3_k127_1302749_1	1396141.BATP01000020_gene50	3.002e-29	123.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_1305692_0	1396141.BATP01000034_gene4232	1.215e-64	233.0	COG0591@1|root,COG0591@2|Bacteria,46XE4@74201|Verrucomicrobia,2IVMU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH3_k127_1305692_1	886293.Sinac_6489	4.188e-62	222.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
DTH3_k127_1311921_1	234267.Acid_2989	4.517e-91	303.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43,RicinB_lectin_2
DTH3_k127_1311921_0	452637.Oter_4283	1.639e-252	794.0	COG0657@1|root,COG0657@2|Bacteria,46TU9@74201|Verrucomicrobia,3KA3K@414999|Opitutae	414999|Opitutae	I	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
DTH3_k127_1313765_2	904296.HMPREF9124_0631	3.161e-34	153.0	28J61@1|root,2Z91S@2|Bacteria,1UYHJ@1239|Firmicutes,24EVG@186801|Clostridia,2PS0Q@265975|Oribacterium	186801|Clostridia	S	Endo-alpha-N-acetylgalactosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_101,Glyco_hydro_129
DTH3_k127_1313765_0	1380391.JIAS01000012_gene4526	2.603e-132	434.0	COG4948@1|root,COG4948@2|Bacteria,1R63G@1224|Proteobacteria,2TT3A@28211|Alphaproteobacteria,2JW8D@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
DTH3_k127_1313765_1	1123242.JH636434_gene3764	4.061e-72	249.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_131708_2	1122179.KB890497_gene2838	5.226e-10	71.0	COG1409@1|root,COG2312@1|root,COG1409@2|Bacteria,COG2312@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
DTH3_k127_131708_1	497964.CfE428DRAFT_4549	2.698e-65	231.0	COG0800@1|root,COG0800@2|Bacteria,46VG5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
DTH3_k127_131708_0	1396418.BATQ01000185_gene2103	2.705e-220	713.0	COG1572@1|root,COG2010@1|root,COG2133@1|root,COG1572@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH3_k127_1322994_1	497964.CfE428DRAFT_2928	4.266e-86	295.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DTH3_k127_1322994_5	478741.JAFS01000001_gene1135	1.625e-18	96.0	COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,37GQX@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
DTH3_k127_1322994_2	478741.JAFS01000001_gene1134	2.381e-78	273.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,37GF6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
DTH3_k127_1322994_0	1156937.MFUM_1050006	3.393e-87	299.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,37G48@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase family, catalytic domain	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH3_k127_1322994_3	497964.CfE428DRAFT_2933	5.031e-66	243.0	COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DTH3_k127_1322994_4	1403819.BATR01000147_gene5029	1.073e-43	166.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia,2ITN2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DTH3_k127_1325387_10	497964.CfE428DRAFT_5952	1.04e-17	83.0	COG0745@1|root,COG0745@2|Bacteria,46V5I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH3_k127_1325387_6	452637.Oter_0887	1.597e-44	183.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1325387_8	497964.CfE428DRAFT_5353	6.88e-24	119.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH3_k127_1325387_9	497964.CfE428DRAFT_4596	2.342e-21	110.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283,ko:K02454,ko:K03220,ko:K03466	ko03070,ko05111,map03070,map05111	M00331,M00332	-	-	ko00000,ko00001,ko00002,ko02035,ko02044,ko03036	3.A.12,3.A.15,3.A.6.1	-	-	Cytochrom_c3_2,FHA,FtsK_SpoIIIE,Response_reg,T2SSE,Yop-YscD_cpl,Yop-YscD_ppl
DTH3_k127_1325387_2	240016.ABIZ01000001_gene4766	1.144e-119	392.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH3_k127_1325387_3	521674.Plim_2302	2.149e-93	321.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DTH3_k127_1325387_1	886293.Sinac_6975	1.502e-153	499.0	28KPG@1|root,2ZA7K@2|Bacteria,2J1E2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1325387_0	1519464.HY22_04590	4.086e-242	768.0	COG0058@1|root,COG0058@2|Bacteria,1FD8Y@1090|Chlorobi	1090|Chlorobi	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
DTH3_k127_1325387_4	497964.CfE428DRAFT_2347	1.405e-71	251.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
DTH3_k127_1325387_5	497964.CfE428DRAFT_2346	1.665e-52	198.0	COG3694@1|root,COG3694@2|Bacteria,46VPX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
DTH3_k127_1325387_7	97139.C824_01928	3.39e-31	125.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_1325775_1	909663.KI867150_gene972	8.044e-16	78.0	2CIE9@1|root,32S7U@2|Bacteria,1P112@1224|Proteobacteria,431TX@68525|delta/epsilon subdivisions,2WWP3@28221|Deltaproteobacteria,2MS3R@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
DTH3_k127_1325775_2	1118153.MOY_06927	3.816e-05	53.0	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1S7JH@1236|Gammaproteobacteria,1XKGS@135619|Oceanospirillales	135619|Oceanospirillales	NU	Type IV Pilus-assembly protein W	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
DTH3_k127_1325775_0	382464.ABSI01000013_gene1773	2.621e-31	140.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1326738_1	935948.KE386494_gene686	4.753e-102	343.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,42FR7@68295|Thermoanaerobacterales	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
DTH3_k127_1326738_0	926569.ANT_13690	4.898e-207	654.0	COG2407@1|root,COG2407@2|Bacteria,2G84V@200795|Chloroflexi	200795|Chloroflexi	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
DTH3_k127_1327190_1	305700.B447_09528	4.717e-76	259.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,2KVKA@206389|Rhodocyclales	206389|Rhodocyclales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
DTH3_k127_1327190_0	661478.OP10G_0590	2.797e-165	548.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
DTH3_k127_1332401_0	1173027.Mic7113_4161	1.025e-172	586.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
DTH3_k127_1332401_6	395961.Cyan7425_0748	5.016e-52	186.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH3_k127_1332401_2	794903.OPIT5_07185	1.488e-129	435.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,46V2T@74201|Verrucomicrobia,3K9RQ@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
DTH3_k127_1332401_8	1380394.JADL01000003_gene4839	4.909e-23	104.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,2JTM5@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
DTH3_k127_1332401_10	1304874.JAFY01000001_gene2557	1.631e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,3TC3U@508458|Synergistetes	508458|Synergistetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
DTH3_k127_1332401_5	382464.ABSI01000011_gene3037	1.384e-77	262.0	COG3837@1|root,COG3837@2|Bacteria,46T0V@74201|Verrucomicrobia,2IU8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH3_k127_1332401_3	215803.DB30_0528	1.287e-101	343.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1332401_4	1123242.JH636435_gene1120	8.245e-97	327.0	COG1506@1|root,COG1506@2|Bacteria,2J1ST@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
DTH3_k127_1332401_9	1303518.CCALI_02658	1.777e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_1332401_1	234267.Acid_2416	4.197e-165	532.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
DTH3_k127_1332401_7	1396418.BATQ01000058_gene90	5.92e-34	132.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DTH3_k127_134553_3	1198452.Jab_2c29700	1.019e-06	62.0	COG3227@1|root,COG3227@2|Bacteria,1R61F@1224|Proteobacteria,2VUWX@28216|Betaproteobacteria,474TB@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	ko:K20273	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
DTH3_k127_134553_1	243090.RB4375	3.749e-24	119.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF642
DTH3_k127_134553_2	1173028.ANKO01000041_gene3212	4.471e-10	67.0	COG2931@1|root,COG2931@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Calx-beta,Chlam_PMP,DUF4347,HemolysinCabind
DTH3_k127_134553_0	1396418.BATQ01000019_gene4979	2.729e-167	547.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia,2ITUY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DTH3_k127_1353781_1	497964.CfE428DRAFT_2620	1.803e-115	377.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH3_k127_1353781_0	671143.DAMO_1541	3.129e-146	473.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
DTH3_k127_1353781_2	452637.Oter_0434	7.092e-46	172.0	COG0835@1|root,COG0835@2|Bacteria,46VRE@74201|Verrucomicrobia,3K82Y@414999|Opitutae	414999|Opitutae	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
DTH3_k127_1353781_4	452637.Oter_0815	0.0009765	48.0	COG0840@1|root,COG0840@2|Bacteria,46THW@74201|Verrucomicrobia,3K9B6@414999|Opitutae	414999|Opitutae	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal
DTH3_k127_1358077_0	481448.Minf_0805	0.0	1214.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,37G3C@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DTH3_k127_1358341_2	309799.DICTH_1451	8.258e-50	186.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DTH3_k127_1358341_7	515635.Dtur_1559	2.792e-17	87.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH3_k127_1358341_6	589865.DaAHT2_0883	6.02e-18	90.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2MMDF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DTH3_k127_1358341_1	1267535.KB906767_gene952	1.062e-154	503.0	COG0673@1|root,COG0673@2|Bacteria,3Y65Y@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_1358341_10	243090.RB7746	3.363e-11	68.0	COG3119@1|root,COG3119@2|Bacteria,2J2HN@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH3_k127_1358341_11	1123508.JH636444_gene5158	4.132e-11	75.0	COG2165@1|root,COG2165@2|Bacteria,2IZG4@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_1358341_9	247490.KSU1_C1333	2.734e-14	83.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_1358341_8	926569.ANT_12920	1.566e-16	87.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
DTH3_k127_1358341_3	646529.Desaci_3169	2.553e-49	188.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,2495M@186801|Clostridia,260GE@186807|Peptococcaceae	186801|Clostridia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DTH3_k127_1358341_4	1396418.BATQ01000166_gene1881	1.081e-46	173.0	COG0299@1|root,COG0615@1|root,COG0299@2|Bacteria,COG0615@2|Bacteria,46SUW@74201|Verrucomicrobia,2IWN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FIM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,Formyl_trans_N
DTH3_k127_1358341_5	1499967.BAYZ01000119_gene3208	3.794e-20	103.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH3_k127_1358341_0	497964.CfE428DRAFT_5970	7.156e-257	805.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia	74201|Verrucomicrobia	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DTH3_k127_1358341_12	1267535.KB906767_gene1409	8.375e-09	62.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria,2JHNA@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
DTH3_k127_1367213_0	1349822.NSB1T_12810	8.737e-137	454.0	COG2189@1|root,COG2189@2|Bacteria,4NHTG@976|Bacteroidetes,2FQKU@200643|Bacteroidia,22YMU@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA methylase	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MerR,N6_N4_Mtase
DTH3_k127_1367213_1	452637.Oter_0123	6.789e-18	87.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
DTH3_k127_1378223_0	1267535.KB906767_gene1403	1.296e-239	769.0	COG3408@1|root,COG3408@2|Bacteria,3Y2YG@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH3_k127_1378223_1	1328313.DS2_07733	4.463e-221	693.0	COG2407@1|root,COG2407@2|Bacteria,1R5ZQ@1224|Proteobacteria,1RNGR@1236|Gammaproteobacteria,469P5@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	L-fucose isomerase, C-terminal domain	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
DTH3_k127_1378223_2	395961.Cyan7425_3030	1.533e-11	72.0	2E1H4@1|root,33JV3@2|Bacteria,1GGCX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1379686_2	497964.CfE428DRAFT_3992	1.752e-12	68.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DTH3_k127_1379686_1	180332.JTGN01000022_gene1511	8.971e-63	229.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24G9W@186801|Clostridia	186801|Clostridia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_1379686_0	398767.Glov_2760	1.486e-80	275.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DTH3_k127_1398651_2	314230.DSM3645_09917	1.251e-18	91.0	COG1082@1|root,COG1082@2|Bacteria,2J21B@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_1398651_1	1121022.ABENE_11795	1.181e-21	99.0	COG1082@1|root,COG1082@2|Bacteria,1NNTS@1224|Proteobacteria	1224|Proteobacteria	G	Alpha-glucosidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97,RicinB_lectin_2
DTH3_k127_1398651_0	1150600.ADIARSV_2649	5.785e-86	304.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1IRH7@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl-hydrolase 97 C-terminal, oligomerisation	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
DTH3_k127_141508_2	886293.Sinac_4672	5.172e-32	131.0	COG1403@1|root,COG1403@2|Bacteria,2J3RR@203682|Planctomycetes	203682|Planctomycetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
DTH3_k127_141508_0	926549.KI421517_gene2208	1.169e-162	523.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47NGQ@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	3.5.1.32	ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
DTH3_k127_141508_1	1210884.HG799462_gene8139	3.774e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,2J028@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH3_k127_1430377_1	331113.SNE_A00630	3.765e-06	60.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,2JGCS@204428|Chlamydiae	204428|Chlamydiae	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
DTH3_k127_1430377_0	1142394.PSMK_09490	2.214e-16	93.0	COG2165@1|root,COG2165@2|Bacteria,2IXM1@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_1435664_0	497964.CfE428DRAFT_3901	7.566e-153	495.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH3_k127_1435664_3	1499967.BAYZ01000119_gene3173	5.651e-53	194.0	28JE3@1|root,2Z98B@2|Bacteria,2NQ8M@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
DTH3_k127_1435664_4	383372.Rcas_1314	5.438e-20	91.0	2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1435664_5	1297865.APJD01000005_gene3689	8.097e-07	60.0	2BPPV@1|root,32IH2@2|Bacteria,1NFYU@1224|Proteobacteria,2UIKJ@28211|Alphaproteobacteria,3K4IG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1435664_1	1123242.JH636434_gene5489	1.518e-139	458.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
DTH3_k127_1435664_2	575540.Isop_3679	1.103e-123	413.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
DTH3_k127_1435664_6	794903.OPIT5_18315	2.747e-05	55.0	COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia,3K7KW@414999|Opitutae	414999|Opitutae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DTH3_k127_1439456_1	497964.CfE428DRAFT_3901	6.889e-17	81.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH3_k127_1439456_0	1396141.BATP01000032_gene4274	6.89e-217	692.0	COG1073@1|root,COG1073@2|Bacteria,46Z70@74201|Verrucomicrobia,2IWQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH3_k127_1439456_2	582744.Msip34_2387	5.543e-06	51.0	28HU5@1|root,2Z80X@2|Bacteria,1R55N@1224|Proteobacteria,2VI32@28216|Betaproteobacteria,2KKGA@206350|Nitrosomonadales	206350|Nitrosomonadales	S	TIGRFAM TIGR03790 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1461820_1	1137269.AZWL01000002_gene6553	2.449e-08	69.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,PA14
DTH3_k127_1461820_0	696747.NIES39_O02270	6.096e-30	140.0	COG2931@1|root,COG4675@1|root,COG2931@2|Bacteria,COG4675@2|Bacteria,1GFPS@1117|Cyanobacteria,1HHVN@1150|Oscillatoriales	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH3_k127_1461820_3	1284352.AOIG01000026_gene489	1.357e-05	60.0	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
DTH3_k127_1461820_2	590998.Celf_3038	1.273e-07	66.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DTH3_k127_1469646_2	1120960.ATXG01000002_gene3034	2.373e-07	66.0	COG1409@1|root,COG3087@1|root,COG1409@2|Bacteria,COG3087@2|Bacteria,2GNU9@201174|Actinobacteria	201174|Actinobacteria	V	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Metallophos,PKD
DTH3_k127_1469646_1	1408473.JHXO01000006_gene1129	1.96e-13	86.0	COG3211@1|root,COG4935@1|root,COG3211@2|Bacteria,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,2G16U@200643|Bacteroidia	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH3_k127_1469646_0	1396141.BATP01000006_gene5432	6.993e-221	748.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH3_k127_1471211_4	794903.OPIT5_12085	7.251e-36	137.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46UZR@74201|Verrucomicrobia,3K795@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
DTH3_k127_1471211_1	309807.SRU_0678	1.773e-105	355.0	COG3829@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
DTH3_k127_1471211_2	452637.Oter_1551	1.637e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,46SRM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_1471211_3	313628.LNTAR_08349	2.601e-54	203.0	COG0472@1|root,COG0472@2|Bacteria	313628.LNTAR_08349|-	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1471211_0	756272.Plabr_1226	1.896e-110	369.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH3_k127_1471211_5	313595.P700755_001507	3.816e-05	53.0	COG0457@1|root,COG4700@1|root,COG0457@2|Bacteria,COG4700@2|Bacteria,4NFCV@976|Bacteroidetes,1HXNV@117743|Flavobacteriia	976|Bacteroidetes	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	BCSC_C,DUF4184,TPR_16,TPR_19,TPR_6,TPR_8
DTH3_k127_1472851_2	530564.Psta_4256	3.724e-20	91.0	COG2010@1|root,COG2133@1|root,COG3474@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH3_k127_1472851_3	521674.Plim_1627	5.254e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_1472851_4	1396141.BATP01000006_gene5432	9.891e-05	54.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH3_k127_1472851_0	452637.Oter_3823	3.645e-67	241.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1472851_1	1209072.ALBT01000067_gene117	1.665e-44	164.0	COG3934@1|root,COG3934@2|Bacteria,1R8GV@1224|Proteobacteria,1SYA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_42
DTH3_k127_1475892_1	1267533.KB906735_gene4670	7.496e-90	304.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_1475892_0	278957.ABEA03000005_gene4380	9.007e-168	536.0	COG0407@1|root,COG0407@2|Bacteria,46WW7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_1475892_2	204669.Acid345_0644	1.523e-05	56.0	COG0383@1|root,COG0383@2|Bacteria,3Y77D@57723|Acidobacteria,2JKQ2@204432|Acidobacteriia	204432|Acidobacteriia	G	Polysaccharide lyase family 4, domain III	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_1480764_5	1396141.BATP01000062_gene4458	0.0008562	43.0	COG1082@1|root,COG2730@1|root,COG3119@1|root,COG3250@1|root,COG3533@1|root,COG4733@1|root,COG5297@1|root,COG1082@2|Bacteria,COG2730@2|Bacteria,COG3119@2|Bacteria,COG3250@2|Bacteria,COG3533@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	AP_endonuc_2,Alginate_lyase,Laminin_G_3,NPCBM
DTH3_k127_1480764_0	1173024.KI912153_gene216	0.0	1677.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH3_k127_1480764_2	1173024.KI912153_gene217	1.875e-153	490.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH3_k127_1480764_3	909663.KI867150_gene2007	1.013e-85	300.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DTH3_k127_1480764_1	765952.PUV_14580	1.213e-308	957.0	COG0365@1|root,COG0365@2|Bacteria,2JFRM@204428|Chlamydiae	204428|Chlamydiae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DTH3_k127_1480764_4	909663.KI867150_gene2007	1.359e-29	123.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DTH3_k127_1483255_1	111780.Sta7437_4041	1.735e-71	243.0	COG1902@1|root,COG1902@2|Bacteria,1FZYT@1117|Cyanobacteria,3VIN3@52604|Pleurocapsales	1117|Cyanobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
DTH3_k127_1483255_2	1173026.Glo7428_3316	5.776e-61	218.0	COG0432@1|root,COG0432@2|Bacteria,1G61Z@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH3_k127_1483255_0	1123242.JH636434_gene3629	3.539e-117	388.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
DTH3_k127_1483255_3	290512.Paes_2385	1.099e-58	216.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH3_k127_1483255_4	1307759.JOMJ01000003_gene1736	8.988e-11	68.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,42V8E@68525|delta/epsilon subdivisions,2WS8I@28221|Deltaproteobacteria,2MAB9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
DTH3_k127_149385_1	1121920.AUAU01000009_gene1881	0.0005807	50.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH3_k127_149385_0	269798.CHU_2379	3.091e-05	55.0	COG0726@1|root,COG3405@1|root,COG0726@2|Bacteria,COG3405@2|Bacteria,4NUMA@976|Bacteroidetes,47UIR@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 11	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_11
DTH3_k127_1497551_0	880526.KE386488_gene811	1.083e-161	529.0	COG1331@1|root,COG1331@2|Bacteria,4NIS8@976|Bacteroidetes,2FRC4@200643|Bacteroidia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1497551_1	1492737.FEM08_16420	6.578e-54	196.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_1499997_0	269482.Bcep1808_6245	1.047e-115	380.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
DTH3_k127_1499997_2	1210884.HG799462_gene8243	2.613e-38	160.0	2F56K@1|root,33XTB@2|Bacteria,2J30K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1499997_1	1123242.JH636434_gene4668	4.639e-59	217.0	COG1520@1|root,COG3221@1|root,COG1520@2|Bacteria,COG3221@2|Bacteria,2J1S1@203682|Planctomycetes	203682|Planctomycetes	P	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_1521916_0	377629.TERTU_2308	1.451e-72	255.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,2PN6F@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Sodium:solute symporter family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH3_k127_1521916_1	330214.NIDE2247	3.33e-37	154.0	COG0587@1|root,COG0587@2|Bacteria,3J0FE@40117|Nitrospirae	2|Bacteria	L	DNA-directed DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
DTH3_k127_152268_2	1396141.BATP01000058_gene1991	3.535e-06	60.0	COG1572@1|root,COG2010@1|root,COG2133@1|root,COG1572@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH3_k127_152268_0	1089551.KE386572_gene3007	2.503e-48	194.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U5KI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HemolysinCabind
DTH3_k127_1532887_2	382464.ABSI01000012_gene2160	4.122e-43	165.0	COG2831@1|root,COG2831@2|Bacteria,46TZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
DTH3_k127_1532887_0	452637.Oter_1611	3.354e-109	364.0	COG1477@1|root,COG1477@2|Bacteria,46V6N@74201|Verrucomicrobia,3K9VB@414999|Opitutae	414999|Opitutae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH3_k127_1532887_3	452637.Oter_1612	2.247e-38	150.0	COG0526@1|root,COG0526@2|Bacteria,46W0W@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
DTH3_k127_1532887_4	452637.Oter_1613	8.89e-19	87.0	2BFNH@1|root,329GX@2|Bacteria,46WJ5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
DTH3_k127_1532887_1	933262.AXAM01000098_gene3457	1.808e-70	252.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
DTH3_k127_1533244_2	237368.SCABRO_00954	3.47e-10	66.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
DTH3_k127_1533244_0	452637.Oter_2229	2.564e-272	867.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
DTH3_k127_1533244_1	700598.Niako_5388	3.424e-52	196.0	COG3669@1|root,COG3669@2|Bacteria,4NWP5@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
DTH3_k127_1565079_0	273068.TTE0217	7.498e-101	341.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia,42HVC@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
DTH3_k127_1565079_1	1280944.HY17_00425	6.078e-58	213.0	COG2273@1|root,COG2273@2|Bacteria,1PG8G@1224|Proteobacteria,2V8W4@28211|Alphaproteobacteria,43XPI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH3_k127_1572616_2	386415.NT01CX_1351	5.099e-32	130.0	COG0622@1|root,COG0622@2|Bacteria,1VADJ@1239|Firmicutes,25CNG@186801|Clostridia,36WYB@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
DTH3_k127_1572616_1	483219.LILAB_36295	1.421e-44	180.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH3_k127_1572616_0	313628.LNTAR_05744	1.944e-85	301.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH3_k127_1572616_3	204669.Acid345_4052	1.234e-15	78.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
DTH3_k127_1575446_2	1304885.AUEY01000019_gene1167	3.9e-80	276.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,42P6V@68525|delta/epsilon subdivisions,2WM6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
DTH3_k127_1575446_0	1304885.AUEY01000003_gene463	6.31e-176	559.0	28M5B@1|root,2ZAJ4@2|Bacteria,1R7Y9@1224|Proteobacteria,42ZPF@68525|delta/epsilon subdivisions,2WUYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1575446_1	264198.Reut_A1205	2.04e-91	315.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2VXQA@28216|Betaproteobacteria,1K3YT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1591921_2	290397.Adeh_1677	6.763e-73	257.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
DTH3_k127_1591921_1	177439.DP0005	2.916e-101	335.0	COG0106@1|root,COG0106@2|Bacteria,1R6J2@1224|Proteobacteria,43B0N@68525|delta/epsilon subdivisions,2X6EQ@28221|Deltaproteobacteria,2MICV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH3_k127_1591921_0	1396141.BATP01000023_gene554	3.96e-112	387.0	COG2340@1|root,COG2340@2|Bacteria,46VC3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
DTH3_k127_160658_1	1156937.MFUM_170017	5.218e-40	155.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,46SFD@74201|Verrucomicrobia,37GE0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
DTH3_k127_160658_2	1396418.BATQ01000073_gene500	2.574e-39	154.0	COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,2IUG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH3_k127_160658_0	925409.KI911562_gene2080	2.698e-148	482.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1IX0E@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_1616716_0	1396141.BATP01000059_gene2565	1.654e-209	663.0	COG1012@1|root,COG1012@2|Bacteria,46TX0@74201|Verrucomicrobia,2IUT7@203494|Verrucomicrobiae	2|Bacteria	C	Aldehyde dehydrogenase family	mmsA	GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050896,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_4667,iYL1228.KPN_04670	Aldedh
DTH3_k127_1616716_1	452637.Oter_0622	5.043e-180	575.0	COG0160@1|root,COG0160@2|Bacteria,46TE8@74201|Verrucomicrobia,3KA3D@414999|Opitutae	2|Bacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	dgdA	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
DTH3_k127_1620394_3	497964.CfE428DRAFT_4938	5.313e-81	273.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
DTH3_k127_1620394_1	497964.CfE428DRAFT_4937	2.086e-115	381.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM phosphate acetyl butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
DTH3_k127_1620394_0	1123508.JH636439_gene825	2.105e-149	486.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_1620394_5	682795.AciX8_0146	4.43e-06	59.0	COG2730@1|root,COG2730@2|Bacteria,3Y39Q@57723|Acidobacteria,2JI8V@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH3_k127_1620394_2	926569.ANT_25800	1.16e-94	323.0	28KCX@1|root,2Z9ZQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1620394_4	368408.Tpen_1559	6.665e-41	153.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1630063_0	497964.CfE428DRAFT_3913	1.256e-159	513.0	COG3119@1|root,COG3119@2|Bacteria,46TFH@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_1630063_2	264732.Moth_0582	2.527e-79	280.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH3_k127_1630063_3	247490.KSU1_C0931	1.21e-21	98.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DTH3_k127_1630063_1	497964.CfE428DRAFT_1789	9.968e-149	482.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
DTH3_k127_1630063_4	74547.PMT_1528	0.0006591	45.0	COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,1G1WQ@1117|Cyanobacteria,1MKJQ@1212|Prochloraceae	1117|Cyanobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
DTH3_k127_1638398_5	573413.Spirs_4003	2.664e-27	118.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH3_k127_1638398_1	583355.Caka_1995	9.525e-98	338.0	COG0472@1|root,COG0472@2|Bacteria,46SNJ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
DTH3_k127_1638398_4	497964.CfE428DRAFT_3096	9.217e-44	166.0	COG0250@1|root,COG0250@2|Bacteria,46SYX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
DTH3_k127_1638398_0	497964.CfE428DRAFT_2775	1.423e-149	499.0	COG0489@1|root,COG0489@2|Bacteria,46UJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
DTH3_k127_1638398_3	497964.CfE428DRAFT_2774	6.09e-49	184.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
DTH3_k127_1638398_2	497964.CfE428DRAFT_2773	3.302e-54	207.0	2F6K4@1|root,33Z30@2|Bacteria,46VYC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
DTH3_k127_1638791_3	1210884.HG799472_gene14911	2.673e-32	130.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_1638791_1	452637.Oter_1003	1.956e-135	443.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
DTH3_k127_1638791_0	497964.CfE428DRAFT_4132	2.866e-177	567.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_1638791_2	497964.CfE428DRAFT_2876	1.761e-86	291.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DTH3_k127_1638791_5	314275.MADE_1013305	2.412e-07	59.0	COG3767@1|root,COG3767@2|Bacteria,1N9HK@1224|Proteobacteria,1SD4Q@1236|Gammaproteobacteria,466Z0@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1638791_4	1216007.AOPM01000046_gene2429	9.583e-09	61.0	COG5662@1|root,COG5662@2|Bacteria,1RJ4M@1224|Proteobacteria,1S23M@1236|Gammaproteobacteria,2Q1EH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	Protein of unknown function (DUF3379)	EBIG1770	-	-	-	-	-	-	-	-	-	-	-	DUF3379
DTH3_k127_1646797_0	497964.CfE428DRAFT_0064	1.743e-56	205.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
DTH3_k127_1646797_1	518766.Rmar_1172	4.137e-51	193.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,4PEVF@976|Bacteroidetes,1FJP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
DTH3_k127_1646797_2	1396418.BATQ01000001_gene1289	1.768e-35	142.0	COG1321@1|root,COG1321@2|Bacteria,46VZN@74201|Verrucomicrobia,2IUJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
DTH3_k127_1646797_3	452637.Oter_1500	4.05e-29	124.0	COG3824@1|root,COG3824@2|Bacteria,46WK7@74201|Verrucomicrobia,3K8CH@414999|Opitutae	414999|Opitutae	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
DTH3_k127_1646797_4	383372.Rcas_3820	2.544e-11	70.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
DTH3_k127_1651394_1	1131269.AQVV01000050_gene418	7.289e-61	212.0	COG2107@1|root,COG2107@2|Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH3_k127_1651394_2	886293.Sinac_6513	6.66e-19	102.0	291K2@1|root,2ZP6D@2|Bacteria,2IZ9X@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
DTH3_k127_1651394_0	1123242.JH636435_gene1022	1.241e-74	269.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
DTH3_k127_1651394_3	1286632.P278_17170	1.896e-13	78.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DTH3_k127_168668_2	478741.JAFS01000002_gene905	0.0004512	44.0	COG1657@1|root,COG1657@2|Bacteria,46TK5@74201|Verrucomicrobia,37G5B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase C-terminal domain	sqhC	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
DTH3_k127_168668_1	338966.Ppro_2630	8.223e-57	208.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DTH3_k127_168668_0	264732.Moth_2127	4.571e-105	349.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,42FGV@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DTH3_k127_1692408_6	1403819.BATR01000059_gene1810	8.708e-88	294.0	COG3119@1|root,COG3119@2|Bacteria,46TQV@74201|Verrucomicrobia,2IWK5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH3_k127_1692408_1	661478.OP10G_0861	9.243e-131	428.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH3_k127_1692408_7	344747.PM8797T_29862	2.264e-84	291.0	COG1082@1|root,COG1082@2|Bacteria,2J0ZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_1692408_5	247634.GPB2148_1563	5.451e-88	304.0	COG3746@1|root,COG3746@2|Bacteria,1NT6B@1224|Proteobacteria,1SM5C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DTH3_k127_1692408_9	290397.Adeh_4006	1.1e-82	284.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DTH3_k127_1692408_10	290397.Adeh_4005	1.593e-82	289.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DTH3_k127_1692408_3	1242864.D187_004631	7.417e-97	338.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
DTH3_k127_1692408_2	1286106.MPL1_06769	4.412e-115	377.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,46073@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
DTH3_k127_1692408_11	452637.Oter_2549	1.154e-69	243.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
DTH3_k127_1692408_8	452637.Oter_2550	2.84e-84	291.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,3K7XM@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH3_k127_1692408_4	452637.Oter_2551	2.383e-96	326.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH3_k127_1692408_12	706587.Desti_5389	8.152e-22	99.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DTH3_k127_1692408_0	595460.RRSWK_03127	2.131e-139	452.0	COG0701@1|root,COG0701@2|Bacteria,2J0GE@203682|Planctomycetes	203682|Planctomycetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
DTH3_k127_1693336_1	195250.CM001776_gene1467	5.673e-67	234.0	COG1012@1|root,COG1012@2|Bacteria,1G2U1@1117|Cyanobacteria,1GYU6@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_1693336_0	1210884.HG799464_gene10819	1.484e-222	700.0	COG1233@1|root,COG1233@2|Bacteria,2IYJC@203682|Planctomycetes	203682|Planctomycetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
DTH3_k127_1693336_2	278957.ABEA03000041_gene2243	1.227e-24	104.0	COG3727@1|root,COG3727@2|Bacteria,46VQU@74201|Verrucomicrobia,3K8JQ@414999|Opitutae	414999|Opitutae	L	DNA mismatch endonuclease Vsr	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
DTH3_k127_1693336_4	1123366.TH3_03429	2.492e-17	87.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2JTP4@204441|Rhodospirillales	204441|Rhodospirillales	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
DTH3_k127_1693336_3	1335757.SPICUR_03845	3.463e-24	108.0	COG2199@1|root,COG3852@1|root,COG3706@2|Bacteria,COG3852@2|Bacteria,1R7HC@1224|Proteobacteria,1RZKN@1236|Gammaproteobacteria,1X0QN@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9
DTH3_k127_1693336_6	1123242.JH636438_gene5714	0.000683	47.0	COG4276@1|root,COG4276@2|Bacteria,2J0FI@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
DTH3_k127_1696199_3	1396141.BATP01000030_gene3715	7.736e-68	244.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH3_k127_1696199_2	595460.RRSWK_04460	1.964e-120	392.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH3_k127_1696199_4	595460.RRSWK_06357	8.78e-07	60.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PmoA
DTH3_k127_1696199_0	886293.Sinac_5476	4.465e-209	681.0	COG0153@1|root,COG1207@1|root,COG0153@2|Bacteria,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	galK	-	2.3.1.209,2.7.1.157,2.7.1.6	ko:K00849,ko:K02406,ko:K18674,ko:K21379	ko00052,ko00520,ko01100,ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map00052,map00520,map01100,map02020,map02040,map04621,map04626,map05132,map05134	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko02035,ko04147	-	-	-	DUF4954,GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg,Hexapep
DTH3_k127_1696199_1	1288963.ADIS_1775	3.196e-177	567.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1703745_0	497964.CfE428DRAFT_6083	1.192e-242	756.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
DTH3_k127_1703745_1	756067.MicvaDRAFT_2865	9.015e-116	382.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH3_k127_1712733_2	1007103.AFHW01000034_gene2097	8.41e-25	107.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,26QK1@186822|Paenibacillaceae	91061|Bacilli	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH3_k127_1712733_4	794903.OPIT5_26490	3.779e-14	76.0	2C4M3@1|root,2ZD1R@2|Bacteria,46WTA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_2
DTH3_k127_1712733_5	1499967.BAYZ01000171_gene5607	2.273e-08	56.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH3_k127_1712733_1	1499967.BAYZ01000171_gene5607	1.14e-36	145.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH3_k127_1712733_0	240016.ABIZ01000001_gene3005	3.974e-82	279.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH3_k127_1712733_6	4113.PGSC0003DMT400031252	0.000146	48.0	COG0071@1|root,KOG0710@2759|Eukaryota,37T95@33090|Viridiplantae,3GHMX@35493|Streptophyta,44JIG@71274|asterids	35493|Streptophyta	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH3_k127_1723957_0	880526.KE386488_gene1576	6.028e-44	181.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1724149_0	616991.JPOO01000003_gene1322	1.516e-294	925.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,23G5Z@178469|Arenibacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
DTH3_k127_1724149_1	1267535.KB906767_gene1828	7.015e-283	890.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	iraD	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11897,ko:K21637	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
DTH3_k127_1724149_2	497964.CfE428DRAFT_6180	1.551e-122	409.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
DTH3_k127_1724149_3	189426.PODO_28355	1.864e-05	51.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,26QNT@186822|Paenibacillaceae	91061|Bacilli	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH3_k127_1725110_2	497964.CfE428DRAFT_5078	1.084e-06	56.0	COG2133@1|root,COG2133@2|Bacteria,46V55@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH3_k127_1725110_0	1303518.CCALI_01797	4.752e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
DTH3_k127_1725110_1	223192.XP_007916209.1	2.013e-14	76.0	COG0119@1|root,KOG2367@2759|Eukaryota,38SM6@33154|Opisthokonta,3NVRE@4751|Fungi,3QJZW@4890|Ascomycota,213FV@147550|Sordariomycetes	4751|Fungi	E	2-isopropylmalate synthase	LEU4	GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DTH3_k127_1739074_3	331678.Cphamn1_1444	2.596e-17	89.0	COG1950@1|root,COG1950@2|Bacteria,1FE4Y@1090|Chlorobi	1090|Chlorobi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DTH3_k127_1739074_1	497964.CfE428DRAFT_0169	5.644e-40	155.0	COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
DTH3_k127_1739074_0	926560.KE387023_gene1926	1.73e-40	153.0	COG0687@1|root,COG0687@2|Bacteria,1WIRI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
DTH3_k127_1748357_1	471870.BACINT_01455	8.57e-81	274.0	COG3507@1|root,COG3507@2|Bacteria,4P1IB@976|Bacteroidetes,2FQ19@200643|Bacteroidia,4AQAG@815|Bacteroidaceae	976|Bacteroidetes	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
DTH3_k127_1748357_2	530564.Psta_1260	3.054e-33	144.0	COG5555@1|root,COG5555@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH3_k127_1748357_0	1396141.BATP01000023_gene713	4.362e-124	403.0	COG3408@1|root,COG4412@1|root,COG3408@2|Bacteria,COG4412@2|Bacteria,46XDF@74201|Verrucomicrobia,2IVJ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1759063_0	1116472.MGMO_20c00270	6.257e-114	382.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1XDKP@135618|Methylococcales	1236|Gammaproteobacteria	C	Tryptophan halogenase	pltM	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
DTH3_k127_1759063_1	671143.DAMO_0701	1.66e-36	150.0	COG0500@1|root,COG2226@2|Bacteria,2NRU8@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
DTH3_k127_1759063_5	998674.ATTE01000001_gene3175	0.0002307	55.0	COG1649@1|root,COG4932@1|root,COG1649@2|Bacteria,COG4932@2|Bacteria,1NP4V@1224|Proteobacteria	1224|Proteobacteria	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
DTH3_k127_1759063_4	160799.PBOR_01905	1.959e-14	88.0	COG1409@1|root,COG3250@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
DTH3_k127_1759063_2	452637.Oter_2184	4.382e-23	116.0	COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae	2|Bacteria	S	SMART Immunoglobulin C2 type	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,Ig_3,VCBS
DTH3_k127_1759063_3	237368.SCABRO_03851	3.626e-16	84.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_1759370_1	1267535.KB906767_gene4118	3.488e-12	68.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
DTH3_k127_1759370_0	1396141.BATP01000060_gene4765	9.048e-31	140.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
DTH3_k127_1759378_1	497964.CfE428DRAFT_3486	2.067e-56	199.0	COG1038@1|root,COG1038@2|Bacteria,46S8N@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Conserved carboxylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
DTH3_k127_1759378_4	1123388.AQWU01000068_gene1033	3.11e-23	105.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1WIMD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
DTH3_k127_1759378_6	384616.Pisl_0649	5.072e-08	57.0	COG0314@1|root,COG1977@1|root,arCOG00534@2157|Archaea,arCOG00536@2157|Archaea,2XQRK@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM molybdopterin biosynthesis MoaE	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
DTH3_k127_1759378_2	1297617.JPJD01000047_gene1362	1.187e-51	195.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DTH3_k127_1759378_0	452637.Oter_0935	2.637e-153	494.0	COG0042@1|root,COG0042@2|Bacteria,46TCT@74201|Verrucomicrobia,3K895@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
DTH3_k127_1759378_5	1173026.Glo7428_2961	2.483e-16	91.0	COG3240@1|root,COG3240@2|Bacteria,1FZV1@1117|Cyanobacteria	1117|Cyanobacteria	I	Phospholipase lecithinase hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
DTH3_k127_1759378_3	497964.CfE428DRAFT_5469	3.865e-37	151.0	COG2067@1|root,COG2067@2|Bacteria,46SR3@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
DTH3_k127_1762453_2	714943.Mucpa_0032	9.377e-19	89.0	COG0726@1|root,COG0726@2|Bacteria,4NFVG@976|Bacteroidetes,1IXI8@117747|Sphingobacteriia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DTH3_k127_1762453_0	497964.CfE428DRAFT_5300	9.423e-160	514.0	COG0673@1|root,COG0673@2|Bacteria,46S8U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_1762453_1	382464.ABSI01000013_gene1723	3.192e-97	349.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
DTH3_k127_1779717_1	386456.JQKN01000006_gene1261	1.138e-42	165.0	COG3177@1|root,arCOG03110@2157|Archaea,2XUN8@28890|Euryarchaeota,23PGE@183925|Methanobacteria	183925|Methanobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
DTH3_k127_1779717_2	1379270.AUXF01000003_gene3363	5.802e-17	83.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	DUF190,P-II
DTH3_k127_1779717_0	1122221.JHVI01000015_gene1707	3.886e-104	347.0	COG3329@1|root,COG3329@2|Bacteria,1WJER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
DTH3_k127_1781421_0	1291050.JAGE01000001_gene867	3.209e-72	258.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH3_k127_1786341_0	497964.CfE428DRAFT_4237	5.965e-88	291.0	COG0363@1|root,COG0363@2|Bacteria,46SD2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1786341_2	497964.CfE428DRAFT_0568	3.548e-61	217.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DTH3_k127_1786341_4	744872.Spica_1041	1.785e-23	112.0	COG2227@1|root,COG2227@2|Bacteria,2J6CB@203691|Spirochaetes	203691|Spirochaetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DTH3_k127_1786341_5	478741.JAFS01000002_gene94	1.293e-17	89.0	COG0792@1|root,COG0792@2|Bacteria,46ZGA@74201|Verrucomicrobia,37H17@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DTH3_k127_1786341_3	1403819.BATR01000167_gene5697	2.289e-28	123.0	COG2453@1|root,COG2453@2|Bacteria,46XSU@74201|Verrucomicrobia,2IWHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Protein-tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
DTH3_k127_1786341_6	497964.CfE428DRAFT_5371	5.286e-05	53.0	COG4121@1|root,COG4121@2|Bacteria	2|Bacteria	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151	ko:K00773,ko:K07319,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110	-	R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko02048,ko03016	-	-	-	DAO,Methyltransf_30
DTH3_k127_1786341_1	1122927.KB895429_gene355	1.887e-81	275.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH3_k127_1787986_1	877455.Metbo_0621	1.918e-22	98.0	COG0139@1|root,arCOG02676@2157|Archaea,2XX3X@28890|Euryarchaeota,23P25@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
DTH3_k127_1787986_2	37727.XP_002152879.1	2.081e-15	78.0	KOG0271@1|root,KOG0271@2759|Eukaryota,3AGU6@33154|Opisthokonta,3Q4J3@4751|Fungi,3RMSV@4890|Ascomycota,20U9D@147545|Eurotiomycetes,3SE7S@5042|Eurotiales	4751|Fungi	G	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,WD40
DTH3_k127_1787986_3	41431.PCC8801_0934	3.455e-08	59.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,3KJA0@43988|Cyanothece	1117|Cyanobacteria	S	PFAM WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Peptidase_C14,TIR_2,WD40
DTH3_k127_1787986_4	448385.sce1953	6.18e-06	58.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH3_k127_1787986_0	382464.ABSI01000011_gene3178	7.649e-34	145.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1791222_2	1396141.BATP01000056_gene3278	8.174e-26	117.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
DTH3_k127_1791222_0	497964.CfE428DRAFT_0965	2.57e-138	450.0	COG1082@1|root,COG1082@2|Bacteria,46UT7@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_1791222_1	886293.Sinac_0541	2.528e-131	427.0	COG0546@1|root,COG0546@2|Bacteria,2IZVE@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH3_k127_181873_1	373994.Riv7116_5659	6.796e-26	126.0	COG1520@1|root,COG1520@2|Bacteria,1GHEB@1117|Cyanobacteria,1HKIG@1161|Nostocales	1117|Cyanobacteria	C	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PPC
DTH3_k127_181873_0	686340.Metal_3113	1.224e-76	293.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,1S0A9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
DTH3_k127_181873_5	497964.CfE428DRAFT_0066	2.095e-06	50.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
DTH3_k127_181873_2	926556.Echvi_3203	1.785e-18	91.0	COG3385@1|root,COG5421@1|root,COG3385@2|Bacteria,COG5421@2|Bacteria,4NXT2@976|Bacteroidetes	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
DTH3_k127_181873_4	1118059.CAHC01000003_gene959	2.304e-08	63.0	COG0507@1|root,COG0507@2|Bacteria,1V27I@1239|Firmicutes,24GPP@186801|Clostridia	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_181873_3	1123242.JH636434_gene4299	5.161e-16	83.0	COG2755@1|root,COG2755@2|Bacteria,2IZUG@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_1827487_1	1408433.JHXV01000025_gene4047	1.958e-23	106.0	COG4935@1|root,COG4935@2|Bacteria,4NH8G@976|Bacteroidetes,1HYKE@117743|Flavobacteriia,2PBFE@246874|Cryomorphaceae	976|Bacteroidetes	O	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD,P_proprotein
DTH3_k127_1827487_3	1286631.X805_30960	0.0005078	53.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
DTH3_k127_1827487_0	1396141.BATP01000003_gene4934	5.141e-61	235.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
DTH3_k127_1827487_2	1303518.CCALI_00044	9.838e-15	84.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_1833484_8	1535422.ND16A_0270	1.221e-05	48.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RQGQ@1236|Gammaproteobacteria,2Q83Y@267889|Colwelliaceae	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_1833484_2	1499967.BAYZ01000171_gene5584	4.285e-125	410.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_1833484_0	1123242.JH636435_gene793	8.503e-188	599.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DTH3_k127_1833484_6	521674.Plim_2739	7.788e-59	217.0	COG0204@1|root,COG0204@2|Bacteria,2IZPB@203682|Planctomycetes	203682|Planctomycetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH3_k127_1833484_1	344747.PM8797T_20643	3.108e-143	476.0	COG1520@1|root,COG1520@2|Bacteria,2IX2Z@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_1833484_7	595460.RRSWK_05296	2.955e-16	93.0	COG1012@1|root,COG1012@2|Bacteria,2IZ2G@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_1833484_5	497964.CfE428DRAFT_4839	8.668e-82	285.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH3_k127_1833484_3	452637.Oter_1107	7.331e-84	289.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
DTH3_k127_1833484_4	497964.CfE428DRAFT_2458	7.918e-82	279.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH3_k127_1855991_3	411901.BACCAC_00254	4.846e-07	59.0	COG3420@1|root,COG3420@2|Bacteria,4NK37@976|Bacteroidetes	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH3_k127_1855991_1	234267.Acid_2668	1.876e-111	370.0	COG0407@1|root,COG0407@2|Bacteria,3Y8YA@57723|Acidobacteria	57723|Acidobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_1855991_2	404380.Gbem_3420	9.284e-77	263.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,43TDJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
DTH3_k127_1855991_0	794903.OPIT5_02510	2.728e-122	407.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH3_k127_1859929_9	1157637.KB892090_gene6039	2.74e-06	55.0	COG1716@1|root,COG1716@2|Bacteria,2GYEE@201174|Actinobacteria	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
DTH3_k127_1859929_1	886293.Sinac_2090	1.783e-200	632.0	COG0823@1|root,COG0823@2|Bacteria,2IZ00@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
DTH3_k127_1859929_0	497964.CfE428DRAFT_5501	6.995e-297	921.0	COG0008@1|root,COG0008@2|Bacteria,46S4X@74201|Verrucomicrobia	74201|Verrucomicrobia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
DTH3_k127_1859929_8	414684.RC1_3800	2.907e-28	124.0	2DB9X@1|root,2Z7ZS@2|Bacteria,1N6CK@1224|Proteobacteria,2U2ME@28211|Alphaproteobacteria,2JWW7@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF3445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3445
DTH3_k127_1859929_5	240292.Ava_2165	2.05e-51	189.0	COG0288@1|root,COG0288@2|Bacteria,1G2EE@1117|Cyanobacteria,1HMI3@1161|Nostocales	1117|Cyanobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DTH3_k127_1859929_4	517418.Ctha_1742	5.035e-53	195.0	COG0041@1|root,COG0041@2|Bacteria,1FDYI@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DTH3_k127_1859929_2	319003.Bra1253DRAFT_02062	6.761e-82	278.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria,3JSC8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1859929_7	497964.CfE428DRAFT_2007	3.637e-33	137.0	COG0558@1|root,COG0558@2|Bacteria,46T66@74201|Verrucomicrobia	74201|Verrucomicrobia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DTH3_k127_1859929_6	194439.CT0662	3.805e-50	181.0	COG1225@1|root,COG1225@2|Bacteria,1FDZX@1090|Chlorobi	1090|Chlorobi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH3_k127_1865971_0	349161.Dred_1010	2.363e-55	210.0	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,249ZV@186801|Clostridia,2637H@186807|Peptococcaceae	186801|Clostridia	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
DTH3_k127_1865971_2	865861.AZSU01000003_gene2027	2.887e-16	88.0	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24EPV@186801|Clostridia,36HUB@31979|Clostridiaceae	186801|Clostridia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
DTH3_k127_1865971_3	1291050.JAGE01000001_gene1091	0.0005888	47.0	COG0358@1|root,COG0358@2|Bacteria,1TSIU@1239|Firmicutes,2495Y@186801|Clostridia,3WI2W@541000|Ruminococcaceae	186801|Clostridia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
DTH3_k127_1865971_1	756067.MicvaDRAFT_0333	4e-17	84.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
DTH3_k127_1876093_2	1121957.ATVL01000007_gene2357	1.155e-37	158.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
DTH3_k127_1876093_1	382464.ABSI01000020_gene153	8.659e-45	171.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1876093_0	497964.CfE428DRAFT_0298	4.505e-50	180.0	COG2258@1|root,COG2258@2|Bacteria,46VBP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1885785_0	1382359.JIAL01000001_gene1690	3.222e-177	575.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3ZP@57723|Acidobacteria,2JI7Y@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
DTH3_k127_189299_0	886293.Sinac_0656	8.07e-243	760.0	COG1053@1|root,COG1053@2|Bacteria,2IYNS@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH3_k127_189299_3	977880.RALTA_A2916	2.352e-22	100.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,1KHET@119060|Burkholderiaceae	28216|Betaproteobacteria	P	tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DTH3_k127_189299_2	215803.DB30_3302	2.678e-38	151.0	2F6YT@1|root,33ZET@2|Bacteria,1Q2TV@1224|Proteobacteria,438FU@68525|delta/epsilon subdivisions,2X3QS@28221|Deltaproteobacteria,2YWVH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_189299_1	497964.CfE428DRAFT_1508	3.319e-241	757.0	COG1620@1|root,COG1620@2|Bacteria,46UQW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	L-lactate permease	-	-	-	-	-	-	-	-	-	-	-	-	Lactate_perm
DTH3_k127_1902759_4	430498.S8AK09	1.895e-08	63.0	COG0666@1|root,KOG4177@2759|Eukaryota,3AJGX@33154|Opisthokonta,3PCUT@4751|Fungi,3R25V@4890|Ascomycota	4751|Fungi	S	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3
DTH3_k127_1902759_5	378753.KRH_07290	0.0003759	47.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,1WA7Y@1268|Micrococcaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
DTH3_k127_1902759_2	195250.CM001776_gene4007	5.685e-32	135.0	COG0454@1|root,COG0456@2|Bacteria,1GHNN@1117|Cyanobacteria,1H4EJ@1129|Synechococcus	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_1902759_3	1096546.WYO_2614	4.792e-10	65.0	COG4453@1|root,COG4453@2|Bacteria,1PW0X@1224|Proteobacteria,2V2IS@28211|Alphaproteobacteria,1JYKH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
DTH3_k127_1902759_0	497964.CfE428DRAFT_5266	1.126e-99	340.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_1902759_1	1121904.ARBP01000009_gene4249	9.222e-90	299.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH3_k127_1929848_0	452637.Oter_2054	1.607e-231	723.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH3_k127_1929848_2	497964.CfE428DRAFT_1374	6.518e-58	220.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
DTH3_k127_1929848_1	688245.CtCNB1_2999	6.42e-63	231.0	COG4643@1|root,COG4643@2|Bacteria,1R5M0@1224|Proteobacteria,2VPIH@28216|Betaproteobacteria,4AAT3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Toprim domain	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	DUF3631,Toprim_3,Toprim_4
DTH3_k127_1933196_2	395961.Cyan7425_2554	2.014e-44	175.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria,3KFRN@43988|Cyanothece	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose reductase	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DTH3_k127_1933196_0	203119.Cthe_2221	3.987e-82	287.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3WGF2@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH3_k127_1933196_1	1294143.H681_11275	6.504e-50	194.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_1936151_0	530564.Psta_3954	6.294e-61	221.0	COG4785@1|root,COG4785@2|Bacteria,2IZYN@203682|Planctomycetes	203682|Planctomycetes	S	May be involved in cell division	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16
DTH3_k127_1936151_1	1121887.AUDK01000023_gene3477	5.49e-13	76.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,1I7I9@117743|Flavobacteriia,2NSYV@237|Flavobacterium	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
DTH3_k127_1948017_1	1282360.ABAC460_18880	3.253e-11	78.0	COG2304@1|root,COG2931@1|root,COG5276@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind,Integrin_beta,PPC,Peptidase_M10_C
DTH3_k127_1948017_0	595460.RRSWK_02125	4.139e-249	827.0	COG1357@1|root,COG1511@1|root,COG2931@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1511@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,2IZ0P@203682|Planctomycetes	203682|Planctomycetes	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Laminin_G_3
DTH3_k127_1949572_1	794903.OPIT5_03205	3.071e-91	306.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,3K7EN@414999|Opitutae	414999|Opitutae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
DTH3_k127_1949572_0	443143.GM18_2242	5.458e-102	353.0	COG2730@1|root,COG2730@2|Bacteria,1R4XH@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH3_k127_1949572_2	180332.JTGN01000003_gene1997	6.13e-39	164.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH3_k127_1965246_1	1408418.JNJH01000001_gene3038	3.733e-63	226.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JQXF@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DTH3_k127_1965246_2	497964.CfE428DRAFT_0088	1.182e-53	199.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_1965246_0	240016.ABIZ01000001_gene2673	8.845e-178	577.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
DTH3_k127_1965889_1	313606.M23134_04526	8.967e-91	320.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,47NSK@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
DTH3_k127_1965889_0	452637.Oter_2229	1.2e-144	478.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
DTH3_k127_1966267_2	1463820.JOGW01000001_gene5446	4.988e-13	80.0	COG1409@1|root,COG5492@1|root,COG1409@2|Bacteria,COG5492@2|Bacteria,2GKTR@201174|Actinobacteria	201174|Actinobacteria	N	polysaccharide lyase family 8	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Lyase_8,Lyase_8_C,Lyase_8_N
DTH3_k127_1966267_0	1396418.BATQ01000020_gene5035	5.011e-207	656.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_1966267_1	497964.CfE428DRAFT_1056	1.257e-118	397.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
DTH3_k127_1966750_1	300852.55771566	3.07e-104	353.0	COG0508@1|root,COG0508@2|Bacteria,1WI1G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH3_k127_1966750_0	105559.Nwat_1144	1.146e-156	507.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
DTH3_k127_1966750_2	1210884.HG799464_gene10380	1.179e-07	53.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
DTH3_k127_1976210_0	682795.AciX8_2232	3.75e-86	308.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2002388_0	886293.Sinac_0540	2.819e-76	261.0	COG0279@1|root,COG0279@2|Bacteria,2IZQU@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
DTH3_k127_2002388_1	722419.PH505_co00060	3.864e-33	134.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,2Q2CW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
DTH3_k127_2004570_1	595460.RRSWK_05428	1.618e-84	295.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH3_k127_2004570_6	314230.DSM3645_18931	8.488e-08	60.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
DTH3_k127_2004570_2	1403819.BATR01000120_gene4247	1.811e-38	155.0	COG3932@1|root,COG3932@2|Bacteria,46T8A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
DTH3_k127_2004570_3	240016.ABIZ01000001_gene760	2.397e-31	138.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like,Usp
DTH3_k127_2004570_4	1089550.ATTH01000001_gene756	3.19e-22	108.0	COG0589@1|root,COG0589@2|Bacteria,4PICI@976|Bacteroidetes,1FK3M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH3_k127_2004570_5	452637.Oter_1439	5.536e-21	98.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
DTH3_k127_2004570_0	1403819.BATR01000124_gene4434	4.803e-87	292.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
DTH3_k127_2012768_0	794903.OPIT5_27315	1.368e-116	384.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	MA20_08125	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_trans_aux,MlaD
DTH3_k127_2012768_5	1167006.UWK_00985	2.21e-14	74.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2012768_4	278957.ABEA03000005_gene4416	7.075e-17	81.0	2EK6E@1|root,33DWT@2|Bacteria,46ZJP@74201|Verrucomicrobia,3K8CQ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
DTH3_k127_2012768_3	765914.ThisiDRAFT_1557	1.249e-17	85.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,1SD8X@1236|Gammaproteobacteria,1WZDZ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2012768_2	520709.F985_03132	7.778e-26	111.0	2EEQQ@1|root,338IE@2|Bacteria,1N816@1224|Proteobacteria,1SR3D@1236|Gammaproteobacteria,3NS16@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2012768_1	330214.NIDE3859	3.64e-46	175.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DTH3_k127_2012768_6	1123037.AUDE01000032_gene2265	2.753e-10	61.0	COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1HWKU@117743|Flavobacteriia	976|Bacteroidetes	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DTH3_k127_201369_0	1313304.CALK_1498	1.363e-107	360.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_201369_2	1266908.AQPB01000038_gene531	1.742e-08	63.0	COG3428@1|root,COG3428@2|Bacteria,1N3Z5@1224|Proteobacteria,1SAN2@1236|Gammaproteobacteria,1WYRT@135613|Chromatiales	135613|Chromatiales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
DTH3_k127_201369_1	1313304.CALK_1499	1.355e-58	209.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0043877,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576	3.1.1.31,3.5.99.6	ko:K01057,ko:K02080,ko:K02564	ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035,R08365	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979,iYO844.BSU02360,iYO844.BSU35020,iZ_1308.Z0825	Glucosamine_iso,PIG-L
DTH3_k127_2045425_0	497964.CfE428DRAFT_2506	4.79e-180	567.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DTH3_k127_2045425_1	344747.PM8797T_15161	4.952e-112	377.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_2045425_3	314230.DSM3645_26609	6.946e-56	204.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
DTH3_k127_2045425_2	452637.Oter_1501	3.406e-103	357.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
DTH3_k127_2047050_2	485917.Phep_4007	3.098e-09	70.0	28KZC@1|root,2ZAEP@2|Bacteria,4NITB@976|Bacteroidetes,1IVQJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2047050_0	497964.CfE428DRAFT_0138	8.583e-120	391.0	28ND0@1|root,2ZBFU@2|Bacteria,46UZ8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2047050_1	452637.Oter_1839	1.763e-31	127.0	COG5492@1|root,COG5492@2|Bacteria,46UXF@74201|Verrucomicrobia,3K8Z6@414999|Opitutae	414999|Opitutae	N	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
DTH3_k127_2072465_4	478741.JAFS01000001_gene1553	3.319e-06	56.0	COG1196@1|root,COG1196@2|Bacteria,46YXU@74201|Verrucomicrobia,37GIU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2072465_2	56107.Cylst_5717	1.232e-14	87.0	COG1413@1|root,COG1672@1|root,COG1413@2|Bacteria,COG1672@2|Bacteria,1G2R4@1117|Cyanobacteria,1HMQH@1161|Nostocales	1117|Cyanobacteria	CT	HEAT repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
DTH3_k127_2072465_3	382464.ABSI01000005_gene1329	7.226e-09	61.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
DTH3_k127_2072465_1	945713.IALB_1744	4.814e-45	168.0	COG0691@1|root,COG0691@2|Bacteria	2|Bacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DTH3_k127_2072465_0	794903.OPIT5_26245	4.476e-147	488.0	COG4796@1|root,COG4796@2|Bacteria,46Y4X@74201|Verrucomicrobia,3K8XV@414999|Opitutae	414999|Opitutae	U	Bacterial type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
DTH3_k127_2073625_1	1396141.BATP01000025_gene931	5.785e-46	172.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DTH3_k127_2073625_2	649639.Bcell_1282	2.796e-28	120.0	2E58T@1|root,33017@2|Bacteria,1VARJ@1239|Firmicutes,4HKU9@91061|Bacilli,1ZHPC@1386|Bacillus	91061|Bacilli	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
DTH3_k127_2073625_0	1303518.CCALI_02909	4.88e-106	357.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
DTH3_k127_2073625_3	234267.Acid_0995	4.805e-17	93.0	COG3391@1|root,COG3391@2|Bacteria,3Y7I2@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2108786_1	243233.MCA2131	2.065e-106	355.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XDW6@135618|Methylococcales	135618|Methylococcales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
DTH3_k127_2108786_2	1238182.C882_0258	1.699e-58	222.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
DTH3_k127_2108786_3	530564.Psta_0781	1.413e-17	91.0	COG1309@1|root,COG1309@2|Bacteria,2J1M7@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH3_k127_2108786_0	468059.AUHA01000006_gene2919	9.665e-197	624.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH3_k127_2109252_2	1210884.HG799466_gene12517	0.0002443	51.0	COG4968@1|root,COG4968@2|Bacteria,2J4X1@203682|Planctomycetes	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_2109252_0	344747.PM8797T_26405	9.539e-106	359.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_2109252_1	575540.Isop_0126	6.514e-14	83.0	COG2165@1|root,COG2165@2|Bacteria,2J1UJ@203682|Planctomycetes	2|Bacteria	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_211018_2	497964.CfE428DRAFT_6006	2.491e-13	70.0	COG0673@1|root,COG0673@2|Bacteria,46TKX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_211018_1	314345.SPV1_01182	5.42e-43	168.0	28N94@1|root,2ZBD8@2|Bacteria,1MWA4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_211018_0	118173.KB235914_gene2616	1.92e-135	456.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
DTH3_k127_2121322_1	794903.OPIT5_11650	2.667e-61	220.0	COG2081@1|root,COG2081@2|Bacteria,46TWE@74201|Verrucomicrobia,3K7FU@414999|Opitutae	414999|Opitutae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
DTH3_k127_2121322_0	452637.Oter_1311	2.408e-75	261.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2121322_2	886293.Sinac_3510	1.806e-29	122.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,PKD
DTH3_k127_2127112_0	1267534.KB906754_gene3772	7.633e-151	484.0	COG1008@1|root,COG1008@2|Bacteria,3Y6ZF@57723|Acidobacteria,2JMB1@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH3_k127_2127112_1	103690.17132598	0.0001602	52.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G3GI@1117|Cyanobacteria,1HM4X@1161|Nostocales	1117|Cyanobacteria	CT	Ntpase (Nacht family)	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
DTH3_k127_2133015_1	555779.Dthio_PD1267	2.225e-15	84.0	COG0667@1|root,COG0667@2|Bacteria,1R77F@1224|Proteobacteria,42Y4Z@68525|delta/epsilon subdivisions,2WTTZ@28221|Deltaproteobacteria,2MCP4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH3_k127_2133015_0	1123277.KB893176_gene3707	0.0	1109.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15,SH3_3,SH3_4,VanY
DTH3_k127_2154045_2	530564.Psta_2284	7.405e-22	98.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH3_k127_2154045_0	1396141.BATP01000001_gene5389	1.467e-231	728.0	COG0659@1|root,COG0659@2|Bacteria,46TUB@74201|Verrucomicrobia,2IVJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
DTH3_k127_2154045_1	909663.KI867150_gene2891	1.704e-80	280.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
DTH3_k127_2157292_1	521674.Plim_0128	2.244e-172	554.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
DTH3_k127_2157292_0	521674.Plim_0129	9.759e-176	573.0	COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,2IY3X@203682|Planctomycetes	203682|Planctomycetes	CL	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
DTH3_k127_2158021_2	1267534.KB906754_gene3777	1.14e-05	47.0	COG1143@1|root,COG1143@2|Bacteria,3Y6N6@57723|Acidobacteria,2JKQS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
DTH3_k127_2158021_0	452637.Oter_0755	1.926e-178	571.0	COG1007@1|root,COG1007@2|Bacteria,46W5N@74201|Verrucomicrobia,3K8V4@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH3_k127_2158021_1	452637.Oter_0754	3.555e-177	565.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,3K7XF@414999|Opitutae	414999|Opitutae	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH3_k127_2169506_1	1396418.BATQ01000025_gene5262	6.469e-105	354.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,2IW1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH3_k127_2169506_0	240016.ABIZ01000001_gene4452	5.772e-105	350.0	COG1577@1|root,COG1577@2|Bacteria,46V85@74201|Verrucomicrobia	74201|Verrucomicrobia	I	mevalonate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH3_k127_2169506_2	234267.Acid_7362	7.727e-94	317.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	2|Bacteria	M	PFAM Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
DTH3_k127_2179001_1	297246.lpp1558	1.981e-08	60.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_29,rve
DTH3_k127_2179001_0	1321778.HMPREF1982_00675	1.046e-108	365.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,26AG8@186813|unclassified Clostridiales	186801|Clostridia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
DTH3_k127_2202362_8	1396141.BATP01000059_gene2568	5.121e-91	302.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
DTH3_k127_2202362_10	1131269.AQVV01000001_gene1323	7.928e-74	263.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2202362_6	497964.CfE428DRAFT_5470	1.061e-97	334.0	COG2204@1|root,COG2204@2|Bacteria,46VVS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH3_k127_2202362_0	497964.CfE428DRAFT_5468	1.492e-190	618.0	COG5000@1|root,COG5000@2|Bacteria,46THS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH3_k127_2202362_5	382464.ABSI01000020_gene123	1.879e-101	344.0	COG3437@1|root,COG3437@2|Bacteria,46Z3C@74201|Verrucomicrobia,2IUIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
DTH3_k127_2202362_11	402626.Rpic_2975	7.785e-62	231.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VZJ3@28216|Betaproteobacteria,1JZS4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	phcS	-	2.7.13.3	ko:K19621	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DTH3_k127_2202362_3	382464.ABSI01000020_gene121	7.562e-121	403.0	COG0500@1|root,COG0500@2|Bacteria,46YTR@74201|Verrucomicrobia,2IU3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Response_reg
DTH3_k127_2202362_12	1458357.BG58_34255	1.311e-57	220.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VMG2@28216|Betaproteobacteria,1K0VE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
DTH3_k127_2202362_16	526222.Desal_3013	1.327e-32	141.0	COG2898@1|root,COG2898@2|Bacteria,1N1JA@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156
DTH3_k127_2202362_9	349521.HCH_05076	9.928e-76	264.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
DTH3_k127_2202362_13	243231.GSU1004	3.483e-45	178.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
DTH3_k127_2202362_7	240016.ABIZ01000001_gene2650	3.144e-97	345.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,2ITQV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
DTH3_k127_2202362_17	111780.Sta7437_2149	1.855e-16	90.0	2CFCI@1|root,32S1P@2|Bacteria,1G4ST@1117|Cyanobacteria,3VJTA@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
DTH3_k127_2202362_4	1158318.ATXC01000001_gene495	2.821e-118	399.0	COG0113@1|root,COG0113@2|Bacteria,2G3MJ@200783|Aquificae	200783|Aquificae	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
DTH3_k127_2202362_18	1403819.BATR01000184_gene6354	2.908e-12	73.0	COG1716@1|root,COG1716@2|Bacteria,46WW1@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
DTH3_k127_2202362_2	1403819.BATR01000184_gene6355	5.222e-142	461.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,2ITTA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DTH3_k127_2202362_14	794903.OPIT5_07630	2.927e-44	166.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,3K8IG@414999|Opitutae	414999|Opitutae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
DTH3_k127_2202362_1	497964.CfE428DRAFT_2609	6.658e-169	542.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DTH3_k127_2202362_19	1462527.CCDM010000002_gene685	5.188e-05	48.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2202362_15	518766.Rmar_0899	5.149e-39	151.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH3_k127_2205793_2	1132442.KB889752_gene1543	8.129e-42	160.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,1ZDT7@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
DTH3_k127_2205793_1	272123.Anacy_0345	2.378e-59	213.0	COG5483@1|root,COG5483@2|Bacteria,1G5J1@1117|Cyanobacteria,1HP7V@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH3_k127_2205793_0	1121004.ATVC01000068_gene1663	2.528e-61	217.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,2VV76@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH3_k127_2205793_4	1121004.ATVC01000068_gene1664	1.158e-17	93.0	2DQR1@1|root,32UPK@2|Bacteria,1NKZE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2205793_3	1232683.ADIMK_1272	2.249e-21	95.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,4673X@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
DTH3_k127_2232017_2	1034345.CAEM01000007_gene1354	1.254e-16	89.0	COG0454@1|root,COG0533@1|root,COG0456@2|Bacteria,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CUKY@84998|Coriobacteriia	84998|Coriobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
DTH3_k127_2232017_1	1042156.CXIVA_02020	1.242e-25	111.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,36IUF@31979|Clostridiaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DTH3_k127_2232017_0	497964.CfE428DRAFT_3691	2.962e-75	262.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH3_k127_2233117_0	671143.DAMO_1057	2.213e-81	287.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
DTH3_k127_2233117_1	398767.Glov_2755	5.434e-64	232.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
DTH3_k127_223917_5	903818.KI912268_gene1848	1.774e-05	47.0	2CI12@1|root,338T1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_223917_2	370438.PTH_1296	1.659e-102	355.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,26141@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
DTH3_k127_223917_3	903814.ELI_2067	2.306e-38	151.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25W8B@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DTH3_k127_223917_4	1123267.JONN01000001_gene1815	7.056e-11	69.0	COG1426@1|root,COG1426@2|Bacteria,1ND8D@1224|Proteobacteria,2UB49@28211|Alphaproteobacteria,2K57P@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
DTH3_k127_223917_0	1210884.HG799462_gene7951	1.426e-233	730.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_223917_1	1210884.HG799462_gene7952	1.551e-197	634.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_2239788_0	1396418.BATQ01000099_gene5573	7.391e-177	565.0	COG3119@1|root,COG3119@2|Bacteria,46XAA@74201|Verrucomicrobia,2IV6B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH3_k127_2239788_4	497964.CfE428DRAFT_0879	1.741e-78	277.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
DTH3_k127_2239788_3	306281.AJLK01000140_gene1050	1.436e-86	308.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1JHUP@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
DTH3_k127_2239788_5	1173026.Glo7428_2699	1.393e-52	193.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH3_k127_2239788_1	1123508.JH636449_gene7422	2.985e-121	424.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH3_k127_2239788_2	243090.RB12844	8.646e-113	372.0	COG3622@1|root,COG3622@2|Bacteria,2J4Z5@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_2239788_6	452637.Oter_0312	4.167e-08	66.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
DTH3_k127_224173_0	497964.CfE428DRAFT_4754	8.403e-66	228.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
DTH3_k127_224173_5	395961.Cyan7425_0454	6.303e-13	70.0	COG3153@1|root,COG3153@2|Bacteria,1GK4X@1117|Cyanobacteria,3KIFY@43988|Cyanothece	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
DTH3_k127_224173_4	296591.Bpro_2383	3.01e-17	90.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VXVS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH3_k127_224173_2	794903.OPIT5_11625	3.134e-61	220.0	COG1451@1|root,COG1451@2|Bacteria,46VW6@74201|Verrucomicrobia,3K7I9@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
DTH3_k127_224173_1	264732.Moth_2023	5.488e-65	245.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,DUF4380
DTH3_k127_224173_3	1227739.Hsw_2709	4.597e-39	166.0	COG3934@1|root,COG3934@2|Bacteria,4NGQC@976|Bacteroidetes,47M9B@768503|Cytophagia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
DTH3_k127_2255390_0	1123508.JH636440_gene2839	4.981e-93	319.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
DTH3_k127_2255390_1	1403819.BATR01000094_gene2930	9.713e-24	101.0	2DQ7E@1|root,3353C@2|Bacteria,46SU5@74201|Verrucomicrobia,2IUQR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
DTH3_k127_2259419_0	1123354.AUDR01000001_gene2019	4.756e-78	265.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KTB7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
DTH3_k127_2259419_2	694440.JOMF01000004_gene1346	2.056e-48	186.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota,2N9E7@224756|Methanomicrobia	224756|Methanomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_2259419_4	469618.FVAG_00642	1.087e-23	105.0	COG3952@1|root,COG3952@2|Bacteria,37AN1@32066|Fusobacteria	32066|Fusobacteria	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
DTH3_k127_2259419_1	1286106.MPL1_00887	5.454e-64	241.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH3_k127_2259419_3	1217656.F964_03877	1.254e-24	114.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria,3NKGV@468|Moraxellaceae	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
DTH3_k127_2272350_6	575540.Isop_1177	6.173e-17	94.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
DTH3_k127_2272350_5	1303518.CCALI_00913	3.137e-17	92.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_2272350_1	1123296.JQKE01000075_gene375	1.698e-37	156.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
DTH3_k127_2272350_4	497964.CfE428DRAFT_0698	9.444e-21	97.0	COG3558@1|root,COG3558@2|Bacteria,46T07@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
DTH3_k127_2272350_2	575609.HMPREF0629_01045	3.334e-22	105.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,22HAS@1570339|Peptoniphilaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH3_k127_2272350_0	1396418.BATQ01000026_gene5276	8.74e-195	613.0	COG0156@1|root,COG0156@2|Bacteria,46SSH@74201|Verrucomicrobia,2ITW1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH3_k127_2272350_3	497964.CfE428DRAFT_4082	1.664e-21	94.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF3472,DUF5077,Gram_pos_anchor,Reprolysin_4
DTH3_k127_2285909_1	1385935.N836_13145	1.97e-15	92.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2285909_0	1396141.BATP01000016_gene2780	4.127e-294	956.0	COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.5.4.40	ko:K18286,ko:K20276	ko00130,ko01110,ko02024,map00130,map01110,map02024	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_8,Big_5,SLH,SWM_repeat
DTH3_k127_2294139_0	1454004.AW11_02080	9.749e-293	907.0	COG0166@1|root,COG0166@2|Bacteria,1PQU4@1224|Proteobacteria,2VKX3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the GPI family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2294139_1	1121920.AUAU01000005_gene1032	2.122e-129	422.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,3Y4JU@57723|Acidobacteria	57723|Acidobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
DTH3_k127_2301986_2	326297.Sama_0297	4.215e-72	247.0	COG3828@1|root,COG3828@2|Bacteria,1QVR0@1224|Proteobacteria,1SN58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl hydrolase family 99	-	-	3.2.1.130	ko:K15538	-	-	-	-	ko00000,ko01000	-	GH99	-	Glyco_hydro_99
DTH3_k127_2301986_0	595460.RRSWK_00087	7.862e-173	566.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_42M
DTH3_k127_2301986_1	509635.N824_15295	1.604e-124	425.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,1IVFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2301986_3	1283287.KB822578_gene2242	3.994e-21	100.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria,4DNZE@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
DTH3_k127_2303538_0	926550.CLDAP_17510	1.837e-142	492.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_2303538_3	1123277.KB893189_gene5243	7.035e-10	73.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,47PGS@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH3_k127_2303538_4	1396141.BATP01000045_gene1848	1.737e-07	65.0	COG2911@1|root,COG3866@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG3866@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH3_k127_2303538_1	509191.AEDB02000022_gene2935	3.625e-111	383.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
DTH3_k127_2303538_2	886293.Sinac_2421	2.563e-29	123.0	COG0673@1|root,COG0673@2|Bacteria,2IWZY@203682|Planctomycetes	203682|Planctomycetes	G	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_2312492_0	667014.Thein_0253	1.183e-66	229.0	COG0473@1|root,COG0473@2|Bacteria,2GGUW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH3_k127_231529_3	1282362.AEAC466_09710	7.764e-17	87.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2U0KF@28211|Alphaproteobacteria,2KHN9@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Malectin
DTH3_k127_231529_0	314230.DSM3645_10902	4.345e-277	876.0	COG0823@1|root,COG1506@1|root,COG4805@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,COG4805@2|Bacteria,2IY8M@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,DUF885,Peptidase_S9,VHL
DTH3_k127_231529_2	794903.OPIT5_27940	2.231e-59	218.0	COG1595@1|root,COG1595@2|Bacteria,46YS4@74201|Verrucomicrobia,3K8W5@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
DTH3_k127_231529_1	497964.CfE428DRAFT_2981	2.194e-104	369.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1648,DUF4019,Pkinase
DTH3_k127_231724_1	118168.MC7420_7993	1.091e-78	290.0	COG0510@1|root,COG0510@2|Bacteria,1G023@1117|Cyanobacteria,1HEZ0@1150|Oscillatoriales	1117|Cyanobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
DTH3_k127_231724_3	42256.RradSPS_2705	2.834e-43	181.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4CS1M@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH3_k127_231724_2	743299.Acife_1001	1.33e-71	258.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,2NDM4@225057|Acidithiobacillales	225057|Acidithiobacillales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
DTH3_k127_231724_0	1173026.Glo7428_4406	6.477e-210	669.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH3_k127_231724_4	329726.AM1_6385	2.517e-13	74.0	COG4671@1|root,COG4671@2|Bacteria,1G0X1@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
DTH3_k127_232326_0	1396141.BATP01000004_gene5894	2.039e-07	65.0	COG1520@1|root,COG2373@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	bipA	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3,CHU_C,DUF11,DUF4347
DTH3_k127_232380_2	671143.DAMO_2920	5.195e-11	67.0	2DRSH@1|root,33CVS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_232380_1	1196083.SALWKB12_1701	4.752e-15	85.0	COG3012@1|root,COG3012@2|Bacteria,1NGS9@1224|Proteobacteria	1224|Proteobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
DTH3_k127_232380_0	497964.CfE428DRAFT_3809	4.777e-61	222.0	COG0330@1|root,COG0330@2|Bacteria,46VZD@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH3_k127_2328653_1	497964.CfE428DRAFT_3528	1.099e-148	475.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Laminin_G_3
DTH3_k127_2328653_0	886293.Sinac_3371	7.192e-278	881.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_2334126_1	1156937.MFUM_230006	3.397e-59	218.0	COG1956@1|root,COG2203@1|root,COG4191@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,37G69@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
DTH3_k127_2334126_3	574087.Acear_2177	7.724e-28	127.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,24CCP@186801|Clostridia,3WAFW@53433|Halanaerobiales	186801|Clostridia	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DTH3_k127_2334126_0	452637.Oter_3564	2.549e-85	298.0	COG2518@1|root,COG2518@2|Bacteria,46UEK@74201|Verrucomicrobia,3K7SY@414999|Opitutae	414999|Opitutae	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
DTH3_k127_2334126_2	1267533.KB906736_gene836	9.868e-51	187.0	COG0060@1|root,COG0060@2|Bacteria,3Y3JW@57723|Acidobacteria,2JIQ2@204432|Acidobacteriia	204432|Acidobacteriia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
DTH3_k127_2363828_3	118173.KB235914_gene3105	5.595e-13	78.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
DTH3_k127_2363828_0	497964.CfE428DRAFT_4990	3.755e-67	249.0	COG3071@1|root,COG3071@2|Bacteria,46VFP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2363828_1	469383.Cwoe_4579	3.013e-60	218.0	COG1994@1|root,COG1994@2|Bacteria,2H6BD@201174|Actinobacteria,4CS7E@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2363828_2	452637.Oter_4555	1.308e-54	197.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2363828_4	335283.Neut_0381	0.0002845	44.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,372NQ@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
DTH3_k127_2370962_0	657309.BXY_26080	1.013e-60	233.0	COG3345@1|root,COG3345@2|Bacteria,4NZUR@976|Bacteroidetes,2FNUD@200643|Bacteroidia	976|Bacteroidetes	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
DTH3_k127_2370962_1	497964.CfE428DRAFT_6276	9.71e-58	224.0	COG2755@1|root,COG2755@2|Bacteria,46SVE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_2370962_2	1270196.JCKI01000009_gene3271	1.051e-14	79.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,1IRH6@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
DTH3_k127_2372343_3	1396141.BATP01000059_gene2521	9.287e-09	68.0	COG2133@1|root,COG2931@1|root,COG3055@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,4.2.2.2	ko:K00428,ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin,fn3
DTH3_k127_2372343_1	1121957.ATVL01000007_gene1972	3.27e-17	96.0	COG3291@1|root,COG3291@2|Bacteria,4NW5Z@976|Bacteroidetes	976|Bacteroidetes	C	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
DTH3_k127_2372343_2	661478.OP10G_1071	2.171e-12	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_2372343_0	497964.CfE428DRAFT_4368	4.765e-57	206.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,PQQ_2,PQQ_3
DTH3_k127_237739_1	794903.OPIT5_04765	6.739e-11	72.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_237739_2	1403313.AXBR01000024_gene4802	7.703e-08	64.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZCBA@1386|Bacillus	91061|Bacilli	G	invertase	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N,RicinB_lectin_2
DTH3_k127_23799_2	1125863.JAFN01000001_gene1060	3.448e-95	333.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_23799_3	243090.RB4127	3.921e-45	175.0	COG3568@1|root,COG3568@2|Bacteria,2IZ9W@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH3_k127_23799_0	497964.CfE428DRAFT_4279	2.949e-161	520.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase middle domain protein	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH3_k127_23799_1	903818.KI912268_gene1381	2.474e-96	329.0	COG3863@1|root,COG3863@2|Bacteria	2|Bacteria	T	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
DTH3_k127_2383350_2	243090.RB10165	8.378e-17	87.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
DTH3_k127_2383350_0	1150600.ADIARSV_4037	1.805e-131	432.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,1INR1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2383350_1	661478.OP10G_2091	1.635e-103	347.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH3_k127_2387893_1	1121468.AUBR01000024_gene3021	1.16e-91	304.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DTH3_k127_2387893_0	1226325.HMPREF1548_02230	1.536e-137	464.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
DTH3_k127_2387893_2	292459.STH3012	2.796e-35	138.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
DTH3_k127_2391388_0	497964.CfE428DRAFT_2154	8.15e-160	535.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH3_k127_2391388_2	99598.Cal7507_3402	1.293e-62	223.0	2EY4W@1|root,33RDQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2391388_1	99598.Cal7507_3403	4.269e-131	433.0	COG0754@1|root,COG0754@2|Bacteria	2|Bacteria	E	glutathionylspermidine amidase activity	gsp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464	3.5.1.78,6.3.1.8	ko:K01460	ko00480,ko01100,map00480,map01100	-	R01917,R01918	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3484	CHAP,GSP_synth
DTH3_k127_2391388_3	99598.Cal7507_3404	2.774e-48	184.0	2F1DQ@1|root,33UEG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2391388_4	435591.BDI_0357	0.0003489	51.0	COG1295@1|root,COG1295@2|Bacteria,4NH0H@976|Bacteroidetes,2FP7P@200643|Bacteroidia,22WV5@171551|Porphyromonadaceae	976|Bacteroidetes	S	ribonuclease BN	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
DTH3_k127_2401517_0	481448.Minf_1718	2.676e-91	326.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,37G03@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
DTH3_k127_2401517_2	457570.Nther_0516	1.925e-29	128.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DTH3_k127_2401517_1	497964.CfE428DRAFT_3928	1.6e-57	201.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia	74201|Verrucomicrobia	D	cell shape determining protein, MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DTH3_k127_2403669_4	886293.Sinac_0541	4.242e-13	69.0	COG0546@1|root,COG0546@2|Bacteria,2IZVE@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH3_k127_2403669_0	589865.DaAHT2_1111	4.98e-263	827.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DTH3_k127_2403669_1	589865.DaAHT2_1112	1.8e-256	806.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
DTH3_k127_2403669_3	344747.PM8797T_28884	2.165e-58	214.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH3_k127_2403669_2	452637.Oter_0906	2.287e-74	267.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH3_k127_2416884_3	587753.EY04_17190	0.0009359	48.0	2D485@1|root,32TGJ@2|Bacteria,1PBDU@1224|Proteobacteria,1S02H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2416884_2	395495.Lcho_1378	5.201e-06	55.0	COG1749@1|root,COG2730@1|root,COG1749@2|Bacteria,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4082,Flg_bb_rod,Flg_bbr_C
DTH3_k127_2416884_0	1121930.AQXG01000008_gene138	9.11e-30	126.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH3_k127_2433269_1	1123508.JH636439_gene990	1.168e-54	197.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_2433269_2	42256.RradSPS_0086	3.354e-22	104.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH3_k127_2433269_0	1396141.BATP01000039_gene1469	2.048e-69	241.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH
DTH3_k127_2469155_3	671143.DAMO_2856	6.815e-105	351.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
DTH3_k127_2469155_11	161156.JQKW01000008_gene436	2.768e-13	75.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K19093	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
DTH3_k127_2469155_10	1304885.AUEY01000005_gene869	7.323e-15	76.0	2DR98@1|root,33ARN@2|Bacteria,1NHFU@1224|Proteobacteria,42X3T@68525|delta/epsilon subdivisions,2WSSX@28221|Deltaproteobacteria,2MMBR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
DTH3_k127_2469155_0	661478.OP10G_0633	4.05e-268	834.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH3_k127_2469155_6	1122917.KB899670_gene4247	4.053e-77	290.0	COG0457@1|root,COG0457@2|Bacteria,1TPP8@1239|Firmicutes,4HCXY@91061|Bacilli,26S7B@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
DTH3_k127_2469155_5	278963.ATWD01000001_gene3347	3.267e-85	298.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
DTH3_k127_2469155_4	204669.Acid345_1044	1.645e-92	313.0	COG2220@1|root,COG2220@2|Bacteria,3Y2TV@57723|Acidobacteria,2JHT8@204432|Acidobacteriia	204432|Acidobacteriia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DTH3_k127_2469155_8	497964.CfE428DRAFT_0226	1.547e-50	185.0	COG0663@1|root,COG0663@2|Bacteria	2|Bacteria	G	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH3_k127_2469155_2	314230.DSM3645_23076	5.169e-122	408.0	COG1520@1|root,COG1520@2|Bacteria,2IXN8@203682|Planctomycetes	203682|Planctomycetes	S	serine threonine protein kinase afsK	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_2469155_7	497964.CfE428DRAFT_4864	5.459e-64	228.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2469155_9	1396141.BATP01000060_gene4559	4.188e-34	146.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
DTH3_k127_2469155_1	1403819.BATR01000020_gene698	4.124e-151	507.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
DTH3_k127_247459_0	481448.Minf_1225	7.279e-84	298.0	COG1033@1|root,COG1033@2|Bacteria,46Z86@74201|Verrucomicrobia,37G0Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
DTH3_k127_2480475_3	237368.SCABRO_01075	5.125e-32	137.0	2AKTZ@1|root,31BM1@2|Bacteria,2J2UU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2480475_5	452637.Oter_3126	2.16e-19	91.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
DTH3_k127_2480475_2	290397.Adeh_3087	2.806e-86	294.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
DTH3_k127_2480475_0	1379698.RBG1_1C00001G0297	8.387e-124	409.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
DTH3_k127_2480475_4	1121920.AUAU01000009_gene1858	3.049e-22	105.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH3_k127_2480475_1	1125863.JAFN01000001_gene561	2.645e-109	363.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
DTH3_k127_2485138_4	452637.Oter_2237	1.324e-58	206.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH3_k127_2485138_7	452637.Oter_2236	6.586e-12	66.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
DTH3_k127_2485138_2	526224.Bmur_0878	1.257e-114	378.0	COG0616@1|root,COG0616@2|Bacteria,2J9E9@203691|Spirochaetes	203691|Spirochaetes	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
DTH3_k127_2485138_3	452637.Oter_0107	4.261e-61	222.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	frnE	-	-	-	-	-	-	-	-	-	-	-	DSBA
DTH3_k127_2485138_0	497964.CfE428DRAFT_6515	3.492e-296	971.0	COG0457@1|root,COG0457@2|Bacteria,46UKC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	FAT,Peptidase_C39_2
DTH3_k127_2485138_5	497964.CfE428DRAFT_2396	4.052e-34	134.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
DTH3_k127_2485138_6	1333856.L686_13365	2.883e-14	79.0	COG0515@1|root,COG0515@2|Bacteria,1NCFW@1224|Proteobacteria	1224|Proteobacteria	KLT	DKNYY family	-	-	-	-	-	-	-	-	-	-	-	-	DKNYY
DTH3_k127_2485138_8	1321774.HMPREF9108_01413	2.048e-09	66.0	COG0515@1|root,COG0515@2|Bacteria,37AZU@32066|Fusobacteria	32066|Fusobacteria	KLT	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DKNYY
DTH3_k127_2485138_1	497964.CfE428DRAFT_2396	1.259e-173	553.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
DTH3_k127_2487227_1	1235803.C825_03120	5.262e-80	271.0	COG1331@1|root,COG1331@2|Bacteria,4NIS8@976|Bacteroidetes,2FRC4@200643|Bacteroidia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2487227_0	509635.N824_01000	1.051e-232	749.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_2487227_2	452637.Oter_1883	2.44e-15	81.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_2495754_4	497964.CfE428DRAFT_1483	7.974e-98	322.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH3_k127_2495754_5	215803.DB30_6514	8.444e-75	265.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YYHJ@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH3_k127_2495754_0	671143.DAMO_0980	2.919e-278	871.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH3_k127_2495754_3	234267.Acid_4784	1.3e-127	424.0	COG0591@1|root,COG0591@2|Bacteria,3Y419@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH3_k127_2495754_1	1403819.BATR01000098_gene3267	2.176e-135	439.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,2ITU4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
DTH3_k127_2495754_2	452637.Oter_1656	7.695e-134	430.0	COG2013@1|root,COG2013@2|Bacteria,46SY6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
DTH3_k127_2495754_6	661478.OP10G_3898	3.578e-69	247.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
DTH3_k127_2495754_7	1210884.HG799462_gene8039	2.543e-41	164.0	COG0845@1|root,COG0845@2|Bacteria,2IYMS@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH3_k127_2499034_0	1123242.JH636435_gene2138	2.96e-109	359.0	COG0673@1|root,COG0673@2|Bacteria,2IX05@203682|Planctomycetes	203682|Planctomycetes	S	NADH-dependent dyhydrogenase related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_2499034_1	1173026.Glo7428_0895	2.739e-69	240.0	COG2110@1|root,COG2110@2|Bacteria,1G5VN@1117|Cyanobacteria	1117|Cyanobacteria	S	phosphatase, C-terminal domain of histone macro H2A1 like protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
DTH3_k127_2499034_2	111781.Lepto7376_0412	4.109e-06	53.0	COG4636@1|root,COG4636@2|Bacteria,1G36C@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DTH3_k127_250523_1	240016.ABIZ01000001_gene1979	7.036e-70	252.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DTH3_k127_250523_2	1122179.KB890464_gene358	1.213e-13	86.0	COG4733@1|root,COG5295@1|root,COG4733@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Flg_new,He_PIG
DTH3_k127_250523_0	472759.Nhal_0193	3.323e-112	404.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
DTH3_k127_2506055_0	1121904.ARBP01000001_gene5918	9.204e-152	509.0	COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,47M3M@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_2507144_0	880073.Calab_1235	2.239e-61	225.0	COG0035@1|root,COG0035@2|Bacteria,2NP5M@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
DTH3_k127_2507144_1	497964.CfE428DRAFT_3693	3.131e-61	225.0	COG0616@1|root,COG0616@2|Bacteria,46SQ5@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
DTH3_k127_2507144_3	696281.Desru_0074	1.038e-18	93.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261Y7@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DTH3_k127_2507144_4	661478.OP10G_4100	0.0002177	44.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,VCBS
DTH3_k127_2507144_2	497964.CfE428DRAFT_0202	1.301e-54	196.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
DTH3_k127_2521615_0	485917.Phep_1293	4.124e-57	224.0	2C4R9@1|root,32RED@2|Bacteria,4P0US@976|Bacteroidetes	976|Bacteroidetes	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH3_k127_2521615_1	566466.NOR53_2254	1.782e-12	78.0	COG2304@1|root,COG2931@1|root,COG3209@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1J94H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MQ	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,He_PIG,HemolysinCabind,VWA_2
DTH3_k127_2529917_0	1254432.SCE1572_17235	3.597e-218	692.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH3_k127_2529919_2	545695.TREAZ_3516	8.711e-67	239.0	COG5492@1|root,COG5492@2|Bacteria,2J5ZN@203691|Spirochaetes	203691|Spirochaetes	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
DTH3_k127_2529919_0	497964.CfE428DRAFT_3584	6.919e-173	551.0	COG5441@1|root,COG5441@2|Bacteria,46U7U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
DTH3_k127_2529919_1	240016.ABIZ01000001_gene2256	2.503e-79	277.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
DTH3_k127_2530263_3	497964.CfE428DRAFT_4543	4.33e-129	420.0	COG1721@1|root,COG1721@2|Bacteria,46TKV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH3_k127_2530263_2	497964.CfE428DRAFT_4542	3.938e-247	782.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,DUF4091,Glyco_hydro_71,HYR,Hint_2,Peptidase_C11
DTH3_k127_2530263_1	497964.CfE428DRAFT_2093	7.849e-252	796.0	COG2304@1|root,COG2304@2|Bacteria,46UTA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2530263_0	497964.CfE428DRAFT_4534	1.717e-261	837.0	COG1196@1|root,COG1196@2|Bacteria,46TX7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2532336_2	530564.Psta_1455	1.688e-24	109.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWZR@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_2532336_3	313612.L8106_03564	1.937e-12	69.0	COG0598@1|root,COG0598@2|Bacteria,1G4WV@1117|Cyanobacteria,1HEGB@1150|Oscillatoriales	1117|Cyanobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
DTH3_k127_2532336_0	240016.ABIZ01000001_gene4794	3.073e-164	529.0	COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia,2ITPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DTH3_k127_2532336_1	1121859.KB890750_gene519	9.834e-51	184.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,47JX4@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH3_k127_2544833_1	1121481.AUAS01000002_gene3607	3.602e-05	48.0	COG0221@1|root,COG0221@2|Bacteria,4PBT1@976|Bacteroidetes,47WA3@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2544833_0	886293.Sinac_6992	2.903e-191	608.0	COG4806@1|root,COG4806@2|Bacteria,2IXTQ@203682|Planctomycetes	203682|Planctomycetes	G	L-rhamnose isomerase	rhaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
DTH3_k127_2554802_2	497964.CfE428DRAFT_4749	1.851e-99	336.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K13598,ko:K13924	ko02020,ko02030,map02020,map02030	M00498,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	ABC_sub_bind,CHASE4,GAF,HAMP,HATPase_c,HDOD,HisKA,PAS,PAS_3,PAS_4,PAS_9
DTH3_k127_2554802_0	497964.CfE428DRAFT_4750	5.112e-199	642.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
DTH3_k127_2554802_1	452637.Oter_2706	4.168e-194	613.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,3K7NC@414999|Opitutae	414999|Opitutae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DTH3_k127_2574754_2	1123242.JH636436_gene531	1.872e-53	189.0	COG1225@1|root,COG4409@1|root,COG4692@1|root,COG1225@2|Bacteria,COG4409@2|Bacteria,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_2574754_0	1123508.JH636439_gene1235	7.95e-243	756.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_2574754_1	886293.Sinac_6968	2.31e-69	239.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
DTH3_k127_2577250_2	452637.Oter_1638	4.673e-78	263.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,3K7NZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_2577250_1	497964.CfE428DRAFT_6512	1.833e-120	399.0	COG0577@1|root,COG0577@2|Bacteria,46SK8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_2577250_0	497964.CfE428DRAFT_6513	9.188e-134	439.0	COG0577@1|root,COG0577@2|Bacteria,46SPG@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_2577361_0	452637.Oter_3485	3.33e-170	546.0	COG2217@1|root,COG2217@2|Bacteria,46S53@74201|Verrucomicrobia,3K7EF@414999|Opitutae	414999|Opitutae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
DTH3_k127_2577361_1	452637.Oter_2839	2.113e-149	482.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH3_k127_2577361_3	497964.CfE428DRAFT_2334	2.344e-46	172.0	COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DTH3_k127_2577361_2	1035308.AQYY01000002_gene233	5.048e-90	309.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
DTH3_k127_2581053_0	1403819.BATR01000178_gene5964	8.952e-144	466.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_2581053_4	1396418.BATQ01000046_gene6162	1.725e-32	134.0	COG0742@1|root,COG0742@2|Bacteria,46T62@74201|Verrucomicrobia,2IUEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
DTH3_k127_2581053_2	28072.Nos7524_0364	5.085e-103	340.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
DTH3_k127_2581053_5	382464.ABSI01000007_gene4120	1.931e-12	74.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia,2IURV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2581053_3	55529.EKX47288	3.482e-101	349.0	COG0144@1|root,KOG1122@2759|Eukaryota	2759|Eukaryota	J	rRNA (cytosine-C5-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
DTH3_k127_2581053_1	497964.CfE428DRAFT_3635	5.55e-141	473.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
DTH3_k127_2584513_2	497964.CfE428DRAFT_6681	5.106e-43	161.0	COG0535@1|root,COG0535@2|Bacteria,46V38@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
DTH3_k127_2584513_1	56107.Cylst_0589	8.167e-60	210.0	COG0714@1|root,COG0714@2|Bacteria,1G1CG@1117|Cyanobacteria,1HJUT@1161|Nostocales	1117|Cyanobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH3_k127_2584513_0	56107.Cylst_0588	4.09e-119	398.0	COG1721@1|root,COG1721@2|Bacteria,1G1ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH3_k127_2584513_3	756067.MicvaDRAFT_0417	1.028e-35	147.0	COG1305@1|root,COG1305@2|Bacteria,1G1YY@1117|Cyanobacteria,1HA69@1150|Oscillatoriales	1117|Cyanobacteria	E	SMART Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH3_k127_2587167_2	56780.SYN_01800	1.271e-31	134.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH3_k127_2587167_0	314230.DSM3645_06659	2.411e-73	265.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
DTH3_k127_2587167_1	543728.Vapar_4986	4.078e-66	241.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria,2VKVF@28216|Betaproteobacteria,4AFFZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315,2.4.1.46	ko:K03429,ko:K03715	ko00561,ko01100,map00561,map01100	-	R02689,R02691,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
DTH3_k127_2587167_3	1189612.A33Q_1380	4.771e-07	55.0	COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,47NX7@768503|Cytophagia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH3_k127_2589056_6	1403819.BATR01000069_gene2089	9.878e-23	102.0	COG4968@1|root,COG4968@2|Bacteria,46VT8@74201|Verrucomicrobia,2IW29@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH3_k127_2589056_2	497964.CfE428DRAFT_4175	8.438e-87	296.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_2589056_5	1142394.PSMK_14730	7.353e-56	207.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH3_k127_2589056_1	278957.ABEA03000202_gene4301	0.0	1073.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH3_k127_2589056_0	497964.CfE428DRAFT_4373	0.0	1112.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DTH3_k127_2589056_3	383372.Rcas_1067	1.363e-72	253.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
DTH3_k127_2589056_4	309799.DICTH_0179	8.071e-59	219.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
DTH3_k127_258916_1	497964.CfE428DRAFT_4033	4.234e-108	355.0	COG0730@1|root,COG0730@2|Bacteria,46VD4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
DTH3_k127_258916_0	366602.Caul_1283	1.122e-108	358.0	COG2730@1|root,COG2730@2|Bacteria,1N2XP@1224|Proteobacteria,2TSHY@28211|Alphaproteobacteria,2KIB4@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH3_k127_2600148_5	861299.J421_5620	3.886e-30	125.0	28J3W@1|root,2Z900@2|Bacteria	2|Bacteria	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
DTH3_k127_2600148_3	448385.sce3153	3.265e-90	302.0	COG0670@1|root,COG0670@2|Bacteria,1R7VN@1224|Proteobacteria,43DVQ@68525|delta/epsilon subdivisions,2WZ04@28221|Deltaproteobacteria,2Z11K@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
DTH3_k127_2600148_6	94122.Shewana3_0285	2.452e-12	69.0	COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,1SGD5@1236|Gammaproteobacteria,2QCT8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
DTH3_k127_2600148_1	278957.ABEA03000091_gene714	2.413e-110	364.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,3K7VW@414999|Opitutae	414999|Opitutae	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DTH3_k127_2600148_0	1403819.BATR01000150_gene5080	2.769e-155	499.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia,2IWM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cobalamin-independent synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
DTH3_k127_2600148_2	1185876.BN8_00813	4.151e-110	363.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
DTH3_k127_2600148_7	682795.AciX8_1050	2.364e-06	59.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria,2JJP2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2600148_4	497964.CfE428DRAFT_1749	1.921e-46	171.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
DTH3_k127_2616627_0	861299.J421_1753	3.727e-271	880.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH3_k127_2621236_0	1298867.AUES01000042_gene3563	2.653e-79	304.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH3_k127_2623890_5	478741.JAFS01000002_gene515	1.412e-06	49.0	COG1012@1|root,COG1012@2|Bacteria,46T21@74201|Verrucomicrobia,37G6H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH3_k127_2623890_3	198628.Dda3937_00205	1.032e-47	176.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,2JE6U@204037|Dickeya	1236|Gammaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
DTH3_k127_2623890_0	1403819.BATR01000164_gene5622	6.261e-222	708.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
DTH3_k127_2623890_4	382464.ABSI01000021_gene406	5.306e-41	156.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
DTH3_k127_2623890_2	1123070.KB899257_gene2284	1.243e-60	216.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,2IU4U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DTH3_k127_2623890_1	926569.ANT_31260	2.86e-120	406.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DTH3_k127_2630237_0	886293.Sinac_6391	2.361e-102	342.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DTH3_k127_2630237_1	452637.Oter_2422	3.022e-69	239.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_2630237_2	1192034.CAP_4540	4.184e-46	191.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,438BB@68525|delta/epsilon subdivisions,2X3KN@28221|Deltaproteobacteria,2YWFV@29|Myxococcales	1224|Proteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08282,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
DTH3_k127_2634686_4	485917.Phep_0675	4.56e-20	93.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
DTH3_k127_2634686_0	761193.Runsl_0074	2.493e-199	640.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
DTH3_k127_2634686_3	278957.ABEA03000095_gene4585	1.634e-24	104.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
DTH3_k127_2634686_2	232348.ADXL01000014_gene730	3.703e-30	122.0	COG4634@1|root,COG4634@2|Bacteria,1G6S3@1117|Cyanobacteria,1H23Q@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2634686_5	700598.Niako_6563	4.666e-08	56.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
DTH3_k127_2634686_6	1042377.AFPJ01000055_gene971	6.057e-07	59.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1S85D@1236|Gammaproteobacteria,468T5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K20988	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
DTH3_k127_2634686_1	886293.Sinac_6122	7.375e-70	242.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
DTH3_k127_263553_2	760568.Desku_1489	3.899e-55	201.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,260D8@186807|Peptococcaceae	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
DTH3_k127_263553_0	247490.KSU1_D0223	2.648e-156	515.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2J2QB@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
DTH3_k127_263553_1	237368.SCABRO_03345	6.415e-64	226.0	COG1456@1|root,COG1456@2|Bacteria,2J2CN@203682|Planctomycetes	203682|Planctomycetes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD,FeS
DTH3_k127_2641612_5	382464.ABSI01000011_gene2968	2.628e-07	55.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2641612_2	760192.Halhy_1640	4.943e-19	88.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1IQJB@117747|Sphingobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
DTH3_k127_2641612_6	1123073.KB899242_gene1643	2.501e-05	57.0	COG1520@1|root,COG5571@1|root,COG1520@2|Bacteria,COG5571@2|Bacteria	2|Bacteria	N	outer membrane autotransporter	yhjY	-	-	ko:K12287,ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,DUF4421,Lipase_GDSL
DTH3_k127_2641612_4	246194.CHY_0024	2.089e-11	68.0	COG0432@1|root,COG0432@2|Bacteria,1V201@1239|Firmicutes,24FTY@186801|Clostridia,42G53@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH3_k127_2641612_3	497964.CfE428DRAFT_4431	1.152e-11	79.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
DTH3_k127_2641612_1	497964.CfE428DRAFT_5098	2.824e-29	137.0	COG1075@1|root,COG1404@1|root,COG3055@1|root,COG3391@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.1.3.6,3.2.1.4	ko:K01179,ko:K03333,ko:K12287	ko00500,ko00984,ko01100,ko01120,map00500,map00984,map01100,map01120	-	R01459,R06200,R11307,R11308	RC00146	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin
DTH3_k127_2641612_0	1123399.AQVE01000001_gene684	1.993e-105	380.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
DTH3_k127_2642112_1	1499967.BAYZ01000095_gene4126	1.271e-104	343.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
DTH3_k127_2642112_2	1403819.BATR01000005_gene177	2.295e-32	145.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia,2IVFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,VCBS
DTH3_k127_2642112_0	223192.XP_007915956.1	2.418e-136	458.0	COG4030@1|root,2SKR2@2759|Eukaryota,39W5K@33154|Opisthokonta,3NXCY@4751|Fungi,3QPYP@4890|Ascomycota,21CB8@147550|Sordariomycetes	4751|Fungi	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH3_k127_2647227_8	1303518.CCALI_02909	2.774e-08	63.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
DTH3_k127_2647227_0	880072.Desac_0610	9.216e-137	466.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DTH3_k127_2647227_6	632518.Calow_0752	7.97e-24	102.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
DTH3_k127_2647227_7	289376.THEYE_A0819	3.69e-17	83.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
DTH3_k127_2647227_3	1382315.JPOI01000001_gene3005	4.162e-87	293.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1WE2C@129337|Geobacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DTH3_k127_2647227_4	497964.CfE428DRAFT_0567	9.702e-45	165.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DTH3_k127_2647227_1	478741.JAFS01000002_gene722	1.452e-120	400.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,37G1T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DTH3_k127_2647227_5	1396141.BATP01000027_gene1118	6.364e-33	130.0	COG0776@1|root,COG0776@2|Bacteria,46T4V@74201|Verrucomicrobia,2IUR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
DTH3_k127_2647227_2	497964.CfE428DRAFT_2267	6.958e-110	361.0	COG0008@1|root,COG0008@2|Bacteria,46SQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH3_k127_2654190_3	537011.PREVCOP_06650	4.461e-05	47.0	2DCAK@1|root,2ZDFX@2|Bacteria,4P6YE@976|Bacteroidetes,2FVHP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DTH3_k127_2654190_2	1379281.AVAG01000028_gene128	3.13e-07	55.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria,431E8@68525|delta/epsilon subdivisions,2WWUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2654190_1	497965.Cyan7822_2990	1.042e-280	868.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,3KJF4@43988|Cyanothece	1117|Cyanobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
DTH3_k127_2654190_0	452637.Oter_0894	0.0	1087.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46U9T@74201|Verrucomicrobia,3K7GP@414999|Opitutae	414999|Opitutae	E	glutamate synthase	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
DTH3_k127_2664916_4	661478.OP10G_4013	3.239e-11	74.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,T2SSG
DTH3_k127_2664916_2	497964.CfE428DRAFT_5027	5.262e-75	272.0	COG1520@1|root,COG1520@2|Bacteria,46U9S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_2664916_3	756272.Plabr_0281	4.123e-12	76.0	COG4968@1|root,COG4968@2|Bacteria,2J53J@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_2664916_1	945713.IALB_2894	4.601e-113	370.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
DTH3_k127_2664916_0	1267535.KB906767_gene4695	4.288e-190	595.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DTH3_k127_2667470_4	991.IW20_16285	3.318e-15	87.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes,1IJ7K@117743|Flavobacteriia,2P0KA@237|Flavobacterium	976|Bacteroidetes	G	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2667470_2	886293.Sinac_0620	1.42e-30	132.0	2EEBB@1|root,30UIG@2|Bacteria,2J420@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2667470_5	197221.22295598	7.785e-06	58.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH3_k127_2667470_3	316067.Geob_3122	2.785e-22	110.0	COG0236@1|root,COG0236@2|Bacteria,1NE99@1224|Proteobacteria	1224|Proteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2667470_1	1227739.Hsw_4156	7.476e-38	159.0	COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DTH3_k127_2667470_0	204669.Acid345_4052	6.257e-167	537.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
DTH3_k127_267764_4	1297617.JPJD01000023_gene1562	0.0001245	54.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,267R3@186813|unclassified Clostridiales	186801|Clostridia	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
DTH3_k127_267764_2	794903.OPIT5_08425	3.516e-13	80.0	COG4968@1|root,COG4968@2|Bacteria,46YJJ@74201|Verrucomicrobia,3K9QQ@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_267764_1	1396141.BATP01000007_gene5570	1.032e-115	407.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH3_k127_267764_3	1303518.CCALI_02638	1.22e-10	72.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_267764_0	886293.Sinac_6980	1.206e-139	447.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_2680363_0	1499967.BAYZ01000141_gene6156	2.366e-38	146.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
DTH3_k127_2680363_2	272123.Anacy_4446	3.153e-20	93.0	COG2442@1|root,COG2442@2|Bacteria,1G7T6@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
DTH3_k127_2680363_3	1303518.CCALI_00532	4.572e-20	99.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
DTH3_k127_2680363_5	278963.ATWD01000001_gene2663	0.0002416	44.0	COG2405@1|root,COG2405@2|Bacteria,3Y95W@57723|Acidobacteria,2JNS5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
DTH3_k127_2680363_6	395961.Cyan7425_2060	0.0002688	44.0	COG2405@1|root,COG2405@2|Bacteria,1G6NZ@1117|Cyanobacteria,3KKNI@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF3368)	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
DTH3_k127_2680363_4	69014.TK0917	4.552e-11	66.0	COG2886@1|root,arCOG00722@2157|Archaea,2Y0J3@28890|Euryarchaeota,244GE@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
DTH3_k127_2680363_1	595460.RRSWK_05050	7.626e-34	133.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH3_k127_268440_3	1081644.IMCC13023_01510	4.053e-27	122.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria	201174|Actinobacteria	S	Na channel or pump	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
DTH3_k127_268440_0	497964.CfE428DRAFT_2523	0.0	1393.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
DTH3_k127_268440_2	562970.Btus_1769	1.696e-109	372.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
DTH3_k127_268440_1	497964.CfE428DRAFT_2485	2.132e-185	587.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_268440_4	693977.Deipr_0877	0.0001629	52.0	COG4700@1|root,COG4700@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	GerE,PLDc_N,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
DTH3_k127_2688766_0	1267535.KB906767_gene933	5.376e-175	557.0	COG3669@1|root,COG3669@2|Bacteria,3Y37T@57723|Acidobacteria,2JKVF@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH3_k127_2688766_2	391625.PPSIR1_04398	4.207e-30	125.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
DTH3_k127_2688766_1	497964.CfE428DRAFT_5146	4.276e-120	394.0	COG1541@1|root,COG1541@2|Bacteria,46UTU@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
DTH3_k127_2691996_2	518766.Rmar_1976	3.336e-24	108.0	28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1FJ7B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
DTH3_k127_2691996_1	1231241.Mc24_08639	4.941e-50	195.0	COG0265@1|root,COG0265@2|Bacteria,2GCIH@200918|Thermotogae	200918|Thermotogae	M	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH3_k127_2691996_0	247490.KSU1_C0522	6.227e-94	317.0	COG1131@1|root,COG1131@2|Bacteria,2IX20@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_2691996_3	1192034.CAP_7501	1.112e-16	85.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2Z111@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH3_k127_2701711_1	497964.CfE428DRAFT_3199	9.668e-30	119.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DTH3_k127_2701711_3	1121101.HMPREF1532_01485	3.614e-07	63.0	COG0860@1|root,COG0860@2|Bacteria,4PPDZ@976|Bacteroidetes,2G15H@200643|Bacteroidia,4ATKG@815|Bacteroidaceae	976|Bacteroidetes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
DTH3_k127_2701711_2	1173028.ANKO01000014_gene1062	8.766e-19	100.0	COG1572@1|root,COG1572@2|Bacteria,1G2VV@1117|Cyanobacteria,1HAEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH3_k127_2701711_0	1123008.KB905706_gene883	2.571e-55	203.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_2702463_1	1121456.ATVA01000012_gene2721	1.596e-29	124.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2M85X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DTH3_k127_2702463_2	497964.CfE428DRAFT_2927	1.308e-28	131.0	COG0206@1|root,COG0206@2|Bacteria,46UWD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DTH3_k127_2702463_0	1396418.BATQ01000141_gene3343	0.0	1136.0	COG4946@1|root,COG4946@2|Bacteria,46TXN@74201|Verrucomicrobia,2IV9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2702975_1	1396141.BATP01000032_gene4274	1.779e-27	117.0	COG1073@1|root,COG1073@2|Bacteria,46Z70@74201|Verrucomicrobia,2IWQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH3_k127_2702975_0	261292.Nit79A3_1788	2.384e-33	150.0	28HU5@1|root,2Z80X@2|Bacteria,1R55N@1224|Proteobacteria,2VI32@28216|Betaproteobacteria,372Y4@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM TIGR03790 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2702975_2	292459.STH487	7.936e-08	64.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
DTH3_k127_2706372_2	497964.CfE428DRAFT_1886	7.871e-125	410.0	COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_2706372_4	388467.A19Y_2770	3.376e-05	53.0	COG4636@1|root,COG4636@2|Bacteria,1G4JH@1117|Cyanobacteria,1H9Q5@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DTH3_k127_2706372_1	497964.CfE428DRAFT_4568	3.387e-127	424.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2706372_3	945713.IALB_0134	4.734e-85	299.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
DTH3_k127_2706372_0	266834.SM_b21056	2.281e-135	482.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,UnbV_ASPIC,VCBS
DTH3_k127_2718986_6	909663.KI867150_gene1090	3.212e-37	141.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
DTH3_k127_2718986_3	909663.KI867150_gene1091	6.626e-60	215.0	2FA6P@1|root,342FE@2|Bacteria	2|Bacteria	S	ATP synthase (E/31 kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
DTH3_k127_2718986_7	909663.KI867150_gene1092	1.125e-36	140.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
DTH3_k127_2718986_8	909663.KI867150_gene1093	7.187e-31	125.0	COG0636@1|root,COG0636@2|Bacteria,1NG0V@1224|Proteobacteria,42XT7@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
DTH3_k127_2718986_5	452637.Oter_1848	2.964e-37	143.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH3_k127_2718986_1	909663.KI867150_gene1094	6.072e-229	726.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42SY2@68525|delta/epsilon subdivisions,2X5C4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
DTH3_k127_2718986_2	909663.KI867150_gene1095	6.217e-108	360.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
DTH3_k127_2718986_9	909663.KI867150_gene1096	3.095e-19	93.0	294CD@1|root,2ZRSF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2718986_4	945713.IALB_0431	1.146e-52	194.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DTH3_k127_2718986_0	497964.CfE428DRAFT_1398	0.0	1071.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U11@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_2722226_4	240016.ABIZ01000001_gene5551	2.83e-24	113.0	COG2931@1|root,COG5267@1|root,COG2931@2|Bacteria,COG5267@2|Bacteria,46YYY@74201|Verrucomicrobia,2ITXB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH3_k127_2722226_1	1499967.BAYZ01000062_gene6031	5.826e-77	280.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH3_k127_2722226_5	458817.Shal_3325	7.812e-05	55.0	COG4932@1|root,COG4932@2|Bacteria,1R94W@1224|Proteobacteria,1RSPU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2722226_3	1123508.JH636441_gene3117	7.153e-34	140.0	COG1413@1|root,COG1413@2|Bacteria,2J2VX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_2722226_0	1382359.JIAL01000001_gene1319	1.563e-175	564.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnC	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
DTH3_k127_2722226_2	861299.J421_1753	2.415e-60	213.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH3_k127_2727292_6	1347086.CCBA010000001_gene1960	3.859e-15	79.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,1ZHUG@1386|Bacillus	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
DTH3_k127_2727292_3	857087.Metme_4292	5.798e-76	269.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1XH04@135618|Methylococcales	1236|Gammaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
DTH3_k127_2727292_1	452637.Oter_1491	3.191e-107	364.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH3_k127_2727292_4	1123508.JH636451_gene5878	2.476e-67	240.0	2DWSV@1|root,341QK@2|Bacteria,2J4FR@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2727292_2	452637.Oter_1490	3.599e-85	287.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
DTH3_k127_2727292_0	497964.CfE428DRAFT_4932	2.666e-130	420.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DTH3_k127_2732759_0	99598.Cal7507_5777	9.212e-21	109.0	2F43W@1|root,33WVC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2733578_0	251221.35211608	9.848e-134	437.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DTH3_k127_2733578_1	497964.CfE428DRAFT_1462	6.339e-72	254.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH3_k127_2737618_0	886293.Sinac_6122	2.305e-232	750.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
DTH3_k127_2737618_1	1396141.BATP01000007_gene5571	1.619e-14	88.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
DTH3_k127_273846_1	247490.KSU1_B0522	1.328e-14	85.0	COG1178@1|root,COG1178@2|Bacteria,2J17C@203682|Planctomycetes	203682|Planctomycetes	U	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
DTH3_k127_273846_2	533240.CRC_01736	8.627e-07	58.0	COG4276@1|root,COG4276@2|Bacteria,1G939@1117|Cyanobacteria,1HNWV@1161|Nostocales	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_273846_0	1121403.AUCV01000002_gene446	1.104e-62	228.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,42P50@68525|delta/epsilon subdivisions,2WKU5@28221|Deltaproteobacteria,2MMX2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
DTH3_k127_2746708_1	497964.CfE428DRAFT_4864	1.154e-55	210.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2746708_0	886293.Sinac_6489	3.165e-90	308.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
DTH3_k127_2755021_0	404589.Anae109_0189	0.0	1451.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
DTH3_k127_2769491_0	886293.Sinac_0430	4.04e-205	658.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXGT@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
DTH3_k127_2777829_3	240016.ABIZ01000001_gene5629	1.145e-30	123.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	CP_0628	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2,VIT
DTH3_k127_2777829_0	526218.Sterm_4083	3.546e-103	350.0	COG5505@1|root,COG5505@2|Bacteria,37B8T@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
DTH3_k127_2777829_1	443143.GM18_3718	7.258e-93	314.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
DTH3_k127_2777829_2	497964.CfE428DRAFT_1669	5.111e-69	241.0	COG0563@1|root,COG0563@2|Bacteria,46SW4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
DTH3_k127_2783072_2	1123070.KB899248_gene14	1.848e-29	128.0	COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DTH3_k127_2783072_0	497964.CfE428DRAFT_4571	6.395e-68	236.0	COG0632@1|root,COG0632@2|Bacteria,46SZF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DTH3_k127_2783072_1	481448.Minf_0381	1.396e-48	182.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,37GQD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
DTH3_k127_2783072_3	497964.CfE428DRAFT_4984	2.693e-29	125.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
DTH3_k127_2788432_4	1484460.JSWG01000009_gene647	1.623e-06	52.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia	976|Bacteroidetes	M	Membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
DTH3_k127_2788432_3	1303518.CCALI_02036	1.016e-13	79.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_2788432_2	903818.KI912268_gene3014	1.514e-18	99.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc
DTH3_k127_2788432_0	443143.GM18_0270	4.453e-43	170.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WIVV@28221|Deltaproteobacteria,43UAF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
DTH3_k127_2788432_1	1048339.KB913029_gene3814	2.827e-25	113.0	COG0406@1|root,COG0406@2|Bacteria,2HUBQ@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
DTH3_k127_2797639_1	204669.Acid345_4072	1.643e-85	291.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
DTH3_k127_2797639_0	1403819.BATR01000067_gene2010	4.602e-114	371.0	COG2326@1|root,COG2326@2|Bacteria,46UWN@74201|Verrucomicrobia,2IVFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
DTH3_k127_2801185_1	497964.CfE428DRAFT_6157	2.197e-10	71.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG4934@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	CHU_C,DUF11,Pro-kuma_activ,SdrD_B
DTH3_k127_2801185_0	485913.Krac_11477	5.005e-141	458.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
DTH3_k127_2804949_2	529818.AMSG_01416T0	2.849e-15	90.0	2BB14@1|root,2S0WY@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2804949_0	1116369.KB890025_gene5278	1.072e-241	774.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,43NRM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
DTH3_k127_2804949_1	111781.Lepto7376_0105	2.892e-41	163.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
DTH3_k127_2805986_1	1123278.KB893574_gene6157	6.46e-161	522.0	COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes,47R5K@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase, family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20b
DTH3_k127_2805986_0	234267.Acid_3901	4.309e-261	829.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Abhydrolase_3,Glyco_hyd_65N_2
DTH3_k127_2805986_3	313628.LNTAR_16943	8.647e-07	57.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
DTH3_k127_2805986_2	530564.Psta_1167	1.156e-104	346.0	COG3119@1|root,COG3119@2|Bacteria	530564.Psta_1167|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2812414_1	521674.Plim_3206	1.76e-78	267.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
DTH3_k127_2812414_0	240016.ABIZ01000001_gene5895	1.352e-130	420.0	COG2133@1|root,COG2133@2|Bacteria,46ZKI@74201|Verrucomicrobia,2IVI9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_2815585_0	1121106.JQKB01000056_gene5865	1.99e-125	418.0	28MUA@1|root,2ZB28@2|Bacteria,1R8RF@1224|Proteobacteria	1224|Proteobacteria	S	Capsule biosynthesis CapC	-	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
DTH3_k127_2815585_5	1906.SFRA_03940	8.283e-14	85.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH3_k127_2815585_8	1033744.CAEL01000023_gene258	0.0007059	53.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,22H03@1570339|Peptoniphilaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
DTH3_k127_2815585_7	1122599.AUGR01000027_gene1284	5.899e-05	57.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RYEM@1236|Gammaproteobacteria,1XHAK@135619|Oceanospirillales	135619|Oceanospirillales	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL,GGDEF
DTH3_k127_2815585_4	96561.Dole_0867	6.194e-14	77.0	COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MJZM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
DTH3_k127_2815585_6	1177154.Y5S_00694	8.063e-11	70.0	2E5B0@1|root,33033@2|Bacteria,1ND0X@1224|Proteobacteria,1SEBX@1236|Gammaproteobacteria,1XMD6@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2815585_1	261292.Nit79A3_3402	8.28e-64	226.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VQN2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
DTH3_k127_2815585_3	351160.RCIX1317	6.732e-16	80.0	COG0286@1|root,arCOG02632@2157|Archaea,2XVXC@28890|Euryarchaeota,2N9DJ@224756|Methanomicrobia	224756|Methanomicrobia	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
DTH3_k127_2815585_2	1499967.BAYZ01000177_gene5729	4.563e-26	108.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DTH3_k127_2821642_2	382464.ABSI01000007_gene4118	2.925e-71	244.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH3_k127_2821642_1	272134.KB731324_gene3229	5.359e-108	367.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DTH3_k127_2821642_4	204669.Acid345_0203	1.284e-08	57.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
DTH3_k127_2821642_0	1168034.FH5T_18125	9.869e-175	559.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_2821642_3	452637.Oter_1389	2.255e-33	132.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH3_k127_2843174_2	266265.Bxe_B2149	1.9e-66	230.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_2843174_0	234267.Acid_4168	2.184e-192	616.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_2843174_1	234267.Acid_4169	8.221e-163	524.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH3_k127_2851156_0	497964.CfE428DRAFT_0232	1.508e-216	689.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2851156_1	497964.CfE428DRAFT_4926	8.425e-40	149.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
DTH3_k127_286327_6	1121022.ABENE_11800	1.683e-49	179.0	COG2382@1|root,COG2382@2|Bacteria,1QU4Q@1224|Proteobacteria,2UCAB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
DTH3_k127_286327_1	1396141.BATP01000001_gene5356	1.79e-142	464.0	COG2382@1|root,COG2382@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH3_k127_286327_3	926566.Terro_1270	2.223e-83	292.0	COG3693@1|root,COG3693@2|Bacteria,3Y6EW@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
DTH3_k127_286327_2	661478.OP10G_2561	1.972e-95	342.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
DTH3_k127_286327_0	1123278.KB893563_gene4551	1.857e-254	808.0	COG3507@1|root,COG3507@2|Bacteria,4NEVJ@976|Bacteroidetes,47JBZ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM_6,Glyco_hydro_43
DTH3_k127_286327_4	583355.Caka_0200	3.24e-69	249.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
DTH3_k127_286327_5	234267.Acid_5864	5.469e-58	215.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_2865433_0	497964.CfE428DRAFT_0210	1.501e-139	458.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia	74201|Verrucomicrobia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DTH3_k127_2865433_1	497964.CfE428DRAFT_5484	1.64e-110	372.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DTH3_k127_2868898_1	65093.PCC7418_0570	4.539e-116	400.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Pesticin,RHS_repeat
DTH3_k127_2868898_0	497964.CfE428DRAFT_4707	5.116e-159	509.0	COG1060@1|root,COG1060@2|Bacteria	2|Bacteria	H	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	mqnC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
DTH3_k127_2868898_2	314230.DSM3645_26734	3.34e-106	355.0	COG0451@1|root,COG0451@2|Bacteria,2IXGI@203682|Planctomycetes	203682|Planctomycetes	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH3_k127_2868898_3	314230.DSM3645_26739	1.912e-07	55.0	COG0329@1|root,COG0329@2|Bacteria,2IXEF@203682|Planctomycetes	203682|Planctomycetes	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
DTH3_k127_2872206_0	1156937.MFUM_90002	6.704e-194	616.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia,37G3Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
DTH3_k127_2872206_1	382464.ABSI01000006_gene874	1.864e-05	51.0	COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_2885763_1	1301098.PKB_0417	2.564e-63	221.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
DTH3_k127_2885763_4	478741.JAFS01000001_gene1060	5.615e-27	114.0	COG2026@1|root,COG2026@2|Bacteria,46Z14@74201|Verrucomicrobia,37H0T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2885763_0	497964.CfE428DRAFT_0539	5.094e-96	317.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
DTH3_k127_2885763_2	497964.CfE428DRAFT_2063	4.438e-35	137.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
DTH3_k127_2885763_3	497964.CfE428DRAFT_2062	7.302e-32	127.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH3_k127_2888727_0	234267.Acid_0753	1.119e-81	286.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_2888727_1	1410620.SHLA_36c000140	3.639e-62	225.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_2889500_0	1379270.AUXF01000006_gene276	1.436e-85	297.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DTH3_k127_2889500_1	742725.HMPREF9450_02179	1.219e-34	141.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,2FNTB@200643|Bacteroidia,22VB5@171550|Rikenellaceae	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH3_k127_2889500_2	985053.VMUT_0013	1.764e-14	78.0	COG5550@1|root,arCOG03744@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2889500_3	518635.BIFANG_02876	2.835e-05	50.0	COG1541@1|root,COG1541@2|Bacteria,2HZHX@201174|Actinobacteria,4D0HV@85004|Bifidobacteriales	201174|Actinobacteria	H	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
DTH3_k127_2893712_5	1396141.BATP01000004_gene5925	5.98e-05	46.0	COG3250@1|root,COG4692@1|root,COG3250@2|Bacteria,COG4692@2|Bacteria,46Z9T@74201|Verrucomicrobia,2IWDF@203494|Verrucomicrobiae	2|Bacteria	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
DTH3_k127_2893712_4	1288298.rosmuc_04261	3.43e-07	53.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria,46S2R@74030|Roseovarius	28211|Alphaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
DTH3_k127_2893712_3	1121127.JAFA01000084_gene4611	9.943e-11	68.0	2DSZ1@1|root,33HZU@2|Bacteria,1PXZ0@1224|Proteobacteria,2WD9I@28216|Betaproteobacteria,1K9SN@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2893712_1	1235802.C823_04890	9.942e-32	139.0	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
DTH3_k127_2893712_0	1396418.BATQ01000019_gene5013	8.128e-52	191.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DTH3_k127_2893712_2	497964.CfE428DRAFT_2503	1.404e-13	72.0	COG1520@1|root,COG1520@2|Bacteria,46TM3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_2906394_5	497964.CfE428DRAFT_0837	2.075e-39	148.0	COG2947@1|root,COG2947@2|Bacteria,46VWG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
DTH3_k127_2906394_3	349741.Amuc_1763	9.469e-67	235.0	COG0325@1|root,COG0325@2|Bacteria,46SV2@74201|Verrucomicrobia,2IU7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
DTH3_k127_2906394_0	1123277.KB893177_gene3516	8.383e-239	756.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,4NK15@976|Bacteroidetes,47MMH@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SGL
DTH3_k127_2906394_7	530564.Psta_0575	3.291e-37	145.0	COG0662@1|root,COG0662@2|Bacteria,2J4Q9@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH3_k127_2906394_6	321332.CYB_1025	2.166e-39	149.0	COG0607@1|root,COG0607@2|Bacteria,1GPXG@1117|Cyanobacteria,1H0XW@1129|Synechococcus	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH3_k127_2906394_2	756499.Desde_1902	2.69e-165	536.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
DTH3_k127_2906394_4	443143.GM18_1309	5.207e-40	156.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
DTH3_k127_2906394_1	56780.SYN_00905	2.016e-167	542.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2MQBJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
DTH3_k127_2918639_1	497964.CfE428DRAFT_4764	6.652e-305	960.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DTH3_k127_2918639_0	234267.Acid_0094	0.0	1065.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE23	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH3_k127_2918639_2	452637.Oter_4534	1.013e-40	152.0	COG0458@1|root,COG0458@2|Bacteria,46UZV@74201|Verrucomicrobia,3K7MQ@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH3_k127_2921970_0	886293.Sinac_6493	2.127e-144	482.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH3_k127_2921970_6	999419.HMPREF1077_03046	1.236e-35	149.0	COG2303@1|root,COG2303@2|Bacteria,4PKTW@976|Bacteroidetes,2FS8M@200643|Bacteroidia,22XM0@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_2921970_2	1403819.BATR01000120_gene4250	1.711e-99	342.0	COG0477@1|root,COG2814@2|Bacteria,46V8K@74201|Verrucomicrobia,2IUV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
DTH3_k127_2921970_4	1121440.AUMA01000008_gene860	5.852e-66	241.0	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria,42VFT@68525|delta/epsilon subdivisions,2WRGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH3_k127_2921970_3	497964.CfE428DRAFT_5265	2.38e-80	282.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2921970_1	661478.OP10G_3197	8.099e-107	367.0	28MB8@1|root,2ZAPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2921970_5	497964.CfE428DRAFT_2917	2.782e-50	183.0	COG0015@1|root,COG0015@2|Bacteria,46UUE@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
DTH3_k127_292568_0	1304872.JAGC01000003_gene2354	9.605e-128	428.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
DTH3_k127_292568_1	1249627.D779_1354	1.753e-52	196.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
DTH3_k127_2942590_0	1396141.BATP01000020_gene108	1.466e-128	451.0	COG2312@1|root,COG4870@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH3_k127_2942590_1	324602.Caur_0211	0.0004022	54.0	COG1319@1|root,COG3391@1|root,COG1319@2|Bacteria,COG3391@2|Bacteria,2GA7F@200795|Chloroflexi,376QS@32061|Chloroflexia	32061|Chloroflexia	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2944873_1	448385.sce4706	1.99e-102	343.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH3_k127_2944873_0	583355.Caka_0067	8.977e-119	389.0	COG0437@1|root,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
DTH3_k127_2944873_2	706587.Desti_4133	3.28e-26	118.0	28JYU@1|root,2Z9NZ@2|Bacteria,1N5J2@1224|Proteobacteria,42UJJ@68525|delta/epsilon subdivisions,2X7XY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2944873_3	497964.CfE428DRAFT_2435	2.479e-21	98.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
DTH3_k127_2952880_0	1297742.A176_07035	1.782e-60	231.0	COG0860@1|root,COG0860@2|Bacteria,1NTG0@1224|Proteobacteria	1224|Proteobacteria	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
DTH3_k127_2956450_4	452637.Oter_2823	8.907e-15	80.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia,3K856@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_2956450_1	1156937.MFUM_810001	5.112e-189	602.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,37G72@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DTH3_k127_2956450_0	240016.ABIZ01000001_gene880	1.711e-241	766.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,2ITI6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc,LacAB_rpiB,SHMT
DTH3_k127_2956450_3	521045.Kole_0482	2.286e-19	102.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SH3_3
DTH3_k127_2956450_2	485913.Krac_5135	1.195e-43	171.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DTH3_k127_2956450_5	1500894.JQNN01000001_gene1070	1.437e-12	76.0	COG5652@1|root,COG5652@2|Bacteria,1MX6C@1224|Proteobacteria,2W1F2@28216|Betaproteobacteria,475D1@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
DTH3_k127_2976019_1	1236514.BAKL01000081_gene4763	2.299e-70	251.0	COG2006@1|root,COG2006@2|Bacteria,4P0ZM@976|Bacteroidetes,2FR0W@200643|Bacteroidia,4APQE@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH3_k127_2976019_3	331678.Cphamn1_0748	3.839e-21	93.0	COG0286@1|root,COG0286@2|Bacteria,1FERX@1090|Chlorobi	1090|Chlorobi	H	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
DTH3_k127_2976019_2	365046.Rta_00040	6.006e-67	230.0	COG0286@1|root,COG0286@2|Bacteria,1NN38@1224|Proteobacteria,2VNIU@28216|Betaproteobacteria,4AGSN@80864|Comamonadaceae	28216|Betaproteobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
DTH3_k127_2976019_0	518766.Rmar_1740	1.289e-106	362.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_2978114_0	700598.Niako_5012	1.042e-12	80.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Amidase_3,ChW,SpoIID
DTH3_k127_2978114_1	203119.Cthe_2878	1.145e-12	79.0	COG3271@1|root,COG3271@2|Bacteria,1VXMN@1239|Firmicutes,251IP@186801|Clostridia,3WPTR@541000|Ruminococcaceae	186801|Clostridia	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
DTH3_k127_2988764_0	344747.PM8797T_13063	2.058e-166	535.0	COG3119@1|root,COG3119@2|Bacteria,2IXUN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_2988764_6	497964.CfE428DRAFT_6518	1.163e-49	193.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DTH3_k127_2988764_2	1414720.CBYM010000003_gene388	3.968e-97	329.0	COG0524@1|root,COG0524@2|Bacteria,1V4QY@1239|Firmicutes,24HRA@186801|Clostridia,36S3G@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH3_k127_2988764_4	1396141.BATP01000057_gene2952	8.46e-72	254.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DTH3_k127_2988764_3	1382356.JQMP01000004_gene323	2.077e-88	302.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
DTH3_k127_2988764_1	861299.J421_3611	2.249e-148	482.0	COG1301@1|root,COG1301@2|Bacteria,1ZT91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
DTH3_k127_2988764_5	497964.CfE428DRAFT_5670	1.561e-69	241.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
DTH3_k127_3009_3	679190.HMPREF0650_1053	1.851e-06	52.0	2DQYP@1|root,339EX@2|Bacteria,4NWWZ@976|Bacteroidetes,2FT6P@200643|Bacteroidia	976|Bacteroidetes	S	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
DTH3_k127_3009_1	411490.ANACAC_00802	1.16e-20	98.0	2DVY7@1|root,32V0C@2|Bacteria,1VAXX@1239|Firmicutes,24P61@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3009_2	1120792.JAFV01000001_gene328	1.981e-08	64.0	2C0VP@1|root,32ZQ9@2|Bacteria,1NENB@1224|Proteobacteria,2UGGI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3009998_1	926560.KE387027_gene1014	8.81e-08	68.0	COG2247@1|root,COG2247@2|Bacteria,1WNI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3009998_0	240292.Ava_4160	1.602e-101	378.0	COG0771@1|root,COG1572@1|root,COG2931@1|root,COG0771@2|Bacteria,COG1572@2|Bacteria,COG2931@2|Bacteria,1GJ9G@1117|Cyanobacteria,1HR22@1161|Nostocales	1117|Cyanobacteria	QU	PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	DUF4347,Lactonase
DTH3_k127_3010509_2	497964.CfE428DRAFT_4938	7.687e-67	235.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
DTH3_k127_3010509_1	1403819.BATR01000134_gene4788	5.399e-124	408.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH3_k127_3010509_0	1210884.HG799463_gene10258	1.666e-145	471.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,2J25N@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase,Acetyltransf_1
DTH3_k127_3015396_1	1265505.ATUG01000001_gene3993	1.656e-63	229.0	COG4313@1|root,COG4313@2|Bacteria,1R6GU@1224|Proteobacteria,43BI4@68525|delta/epsilon subdivisions,2X6WJ@28221|Deltaproteobacteria,2MKN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DTH3_k127_3015396_0	452637.Oter_0816	7.822e-73	248.0	COG1350@1|root,COG1350@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH3_k127_302232_2	62928.azo2096	2.438e-09	68.0	COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,2VJ0W@28216|Betaproteobacteria,2KV1F@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
DTH3_k127_302232_0	1397666.RS24_01915	2.605e-75	266.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,4BPNB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	NU	Type II/IV secretion system protein	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DTH3_k127_302232_1	452637.Oter_3808	3.826e-31	124.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia,3K99W@414999|Opitutae	414999|Opitutae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH3_k127_3028036_1	1121918.ARWE01000001_gene3243	1.536e-28	119.0	2DN4U@1|root,32VHV@2|Bacteria,1NDP9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3028036_2	56110.Oscil6304_4139	0.000885	46.0	COG0286@1|root,COG0286@2|Bacteria,1G0GY@1117|Cyanobacteria,1H88E@1150|Oscillatoriales	1117|Cyanobacteria	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
DTH3_k127_3028036_0	1303518.CCALI_02844	2.07e-140	459.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
DTH3_k127_3029015_0	497964.CfE428DRAFT_0259	2.264e-42	159.0	COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH3_k127_3029015_1	278957.ABEA03000019_gene1865	4.364e-32	133.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
DTH3_k127_3029015_2	404380.Gbem_3451	1.797e-17	85.0	COG1215@1|root,COG1215@2|Bacteria,1NFA4@1224|Proteobacteria,42WEV@68525|delta/epsilon subdivisions,2WS1J@28221|Deltaproteobacteria,43U0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
DTH3_k127_3047840_4	589924.Ferp_2052	8.694e-19	91.0	arCOG03086@1|root,arCOG03086@2157|Archaea,2Y7EV@28890|Euryarchaeota,247AD@183980|Archaeoglobi	183980|Archaeoglobi	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DTH3_k127_3047840_3	330214.NIDE2936	5.49e-19	89.0	COG1598@1|root,COG1598@2|Bacteria,3J1EZ@40117|Nitrospirae	40117|Nitrospirae	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3047840_2	595460.RRSWK_04460	7.081e-26	108.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH3_k127_3047840_0	1396418.BATQ01000136_gene3697	3.274e-288	897.0	COG0665@1|root,COG0665@2|Bacteria,46TKJ@74201|Verrucomicrobia,2IWQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH3_k127_3047840_1	583355.Caka_0805	4.718e-28	113.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
DTH3_k127_308443_4	161156.JQKW01000013_gene170	3.864e-29	120.0	COG0190@1|root,COG0190@2|Bacteria,2GH19@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH3_k127_308443_0	903818.KI912268_gene1122	0.0	1129.0	COG3383@1|root,COG3383@2|Bacteria,3Y2KP@57723|Acidobacteria	57723|Acidobacteria	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
DTH3_k127_308443_1	1042877.GQS_04965	6.562e-235	746.0	COG1894@1|root,COG4231@1|root,arCOG01609@2157|Archaea,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota,243V2@183968|Thermococci	183968|Thermococci	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
DTH3_k127_308443_3	476272.RUMHYD_00357	1.593e-40	156.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
DTH3_k127_308443_2	504728.K649_12990	8.097e-70	244.0	COG1526@1|root,COG1526@2|Bacteria,1WJAY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DTH3_k127_308576_1	111781.Lepto7376_0105	6.332e-33	148.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
DTH3_k127_308576_3	247490.KSU1_B0587	5.397e-11	76.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Peptidase_S74
DTH3_k127_308576_2	1297742.A176_05728	6.036e-25	112.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
DTH3_k127_308576_0	926569.ANT_30710	6.249e-88	301.0	COG1957@1|root,COG1957@2|Bacteria,2G7IF@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
DTH3_k127_3090942_3	1192034.CAP_8755	5.018e-34	137.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42UCT@68525|delta/epsilon subdivisions,2WPAW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DTH3_k127_3090942_2	497964.CfE428DRAFT_6105	3.762e-75	263.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DTH3_k127_3090942_1	497964.CfE428DRAFT_2602	1.48e-155	507.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
DTH3_k127_3090942_4	240016.ABIZ01000001_gene3599	2.146e-26	109.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB-1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH3_k127_3090942_5	1210884.HG799464_gene11269	4.211e-08	54.0	COG0681@1|root,COG0681@2|Bacteria,2J14X@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3090942_0	1123508.JH636440_gene2840	3.109e-168	544.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3098882_2	1167006.UWK_02172	5.019e-29	118.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42ZBZ@68525|delta/epsilon subdivisions,2X5D0@28221|Deltaproteobacteria,2MMNI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	MacB_PCD
DTH3_k127_3098882_0	517418.Ctha_1399	3.516e-202	656.0	COG1331@1|root,COG1331@2|Bacteria,1FDQN@1090|Chlorobi	1090|Chlorobi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
DTH3_k127_3098882_3	1123070.KB899249_gene301	4.115e-11	72.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,2IUVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DTH3_k127_3098882_1	1382306.JNIM01000001_gene2623	7.024e-37	144.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DTH3_k127_3116239_0	1396141.BATP01000009_gene2639	2.019e-207	650.0	COG0477@1|root,COG2814@2|Bacteria,46Z9E@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_3116239_3	886293.Sinac_2107	5.799e-113	373.0	COG0329@1|root,COG0329@2|Bacteria,2IYE2@203682|Planctomycetes	203682|Planctomycetes	EM	Dihydrodipicolinate synthase N-acetylneuraminate lyase	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
DTH3_k127_3116239_1	344747.PM8797T_29708	2.794e-179	568.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
DTH3_k127_3116239_2	1396418.BATQ01000150_gene2240	6.616e-175	557.0	COG2942@1|root,COG2942@2|Bacteria,46UIM@74201|Verrucomicrobia,2ITK6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
DTH3_k127_3116239_5	1303518.CCALI_02288	1.114e-48	188.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_3116239_4	344747.PM8797T_10954	1.507e-67	235.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_3132624_1	481448.Minf_1939	1.566e-87	297.0	COG1085@1|root,COG1085@2|Bacteria,46V5Q@74201|Verrucomicrobia,37G78@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
DTH3_k127_3132624_0	240016.ABIZ01000001_gene1742	5.609e-113	377.0	COG1861@1|root,COG1861@2|Bacteria,46UVT@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
DTH3_k127_3139434_0	497964.CfE428DRAFT_2340	3.224e-103	344.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3139434_2	497964.CfE428DRAFT_2340	4.95e-76	261.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3139434_1	1249627.D779_3087	3.813e-91	307.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RN50@1236|Gammaproteobacteria,1WXR5@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM release factor H-coupled RctB family protein	-	-	-	ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001	-	-	-	RtcB
DTH3_k127_3140325_0	929562.Emtol_1353	7.227e-159	518.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
DTH3_k127_3140325_1	452637.Oter_0714	6.275e-59	211.0	COG1595@1|root,COG1639@1|root,COG1595@2|Bacteria,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HDOD,Sigma70_r2,Sigma70_r4_2
DTH3_k127_3146330_0	1288494.EBAPG3_18410	0.0	1056.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,37271@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DNA topoisomerase, type IA, central	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
DTH3_k127_3146330_1	1396141.BATP01000056_gene3278	3.759e-51	206.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
DTH3_k127_3148876_0	240016.ABIZ01000001_gene2256	3.351e-271	875.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
DTH3_k127_3152818_2	309799.DICTH_0179	2.476e-57	209.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
DTH3_k127_3152818_0	313624.NSP_23270	1.167e-176	559.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria,1HM8T@1161|Nostocales	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH3_k127_3152818_1	452637.Oter_3990	1.134e-138	449.0	COG0451@1|root,COG0451@2|Bacteria,46TXA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH3_k127_3152818_4	1218076.BAYB01000008_gene1536	2.321e-06	60.0	COG2244@1|root,COG2244@2|Bacteria,1R6ME@1224|Proteobacteria,2VNGZ@28216|Betaproteobacteria,1K460@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	rfbE	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DTH3_k127_3152818_3	491916.RHECIAT_CH0001616	9.379e-09	66.0	COG2227@1|root,COG2227@2|Bacteria,1RAQ6@1224|Proteobacteria,2U62S@28211|Alphaproteobacteria,4B9C2@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
DTH3_k127_3153482_2	1396141.BATP01000030_gene3637	6.66e-06	60.0	COG2133@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3828@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,ThuA
DTH3_k127_3153482_0	489825.LYNGBM3L_30850	2.109e-157	538.0	COG2843@1|root,COG2843@2|Bacteria,1G20Q@1117|Cyanobacteria,1H7BE@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
DTH3_k127_3153482_1	44251.PDUR_25010	2.246e-98	332.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,26R0E@186822|Paenibacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DTH3_k127_3155635_4	497964.CfE428DRAFT_1407	3.413e-07	53.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DTH3_k127_3155635_3	1385935.N836_35430	7.44e-31	127.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3155635_5	749414.SBI_05800	2.435e-05	51.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria	201174|Actinobacteria	L	DNA replication protein	-	-	-	ko:K02315,ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
DTH3_k127_3155635_2	880072.Desac_0910	5.02e-31	128.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria	1224|Proteobacteria	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HTH_31,HsdM_N,N6_Mtase
DTH3_k127_3155635_1	1192034.CAP_5127	3.658e-33	146.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,4341P@68525|delta/epsilon subdivisions,2X4PD@28221|Deltaproteobacteria,2YZCK@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
DTH3_k127_3155635_0	661478.OP10G_0514	1.172e-141	459.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,F5_F8_type_C,Lactonase,Phosphoesterase
DTH3_k127_3161289_1	886293.Sinac_0942	1.098e-223	703.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH3_k127_3161289_4	448385.sce0162	1.902e-47	182.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH3_k127_3161289_2	595460.RRSWK_05849	3.195e-137	454.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,2J2W6@203682|Planctomycetes	203682|Planctomycetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
DTH3_k127_3161289_0	595460.RRSWK_06189	1.07e-260	829.0	COG1894@1|root,COG1894@2|Bacteria,2IXJ8@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
DTH3_k127_3161289_3	497964.CfE428DRAFT_5712	5.989e-96	323.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_3170614_2	395495.Lcho_0773	1.628e-23	100.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
DTH3_k127_3170614_3	1056820.KB900700_gene1152	2.233e-22	104.0	COG2968@1|root,COG2968@2|Bacteria,1RC2K@1224|Proteobacteria,1S244@1236|Gammaproteobacteria,2PQ3U@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
DTH3_k127_3170614_0	477974.Daud_1182	1.064e-62	227.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,260K3@186807|Peptococcaceae	186801|Clostridia	E	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
DTH3_k127_3170614_1	2903.EOD40718	1.276e-24	107.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
DTH3_k127_3180338_1	573413.Spirs_4003	9.863e-165	535.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
DTH3_k127_3180338_4	1121447.JONL01000003_gene3289	8.548e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria,42VPE@68525|delta/epsilon subdivisions,2WRZ3@28221|Deltaproteobacteria,2MBFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
DTH3_k127_3180338_0	886293.Sinac_7042	1.449e-319	1012.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
DTH3_k127_3180338_3	639030.JHVA01000001_gene3130	2.198e-12	74.0	2BIJA@1|root,32CS2@2|Bacteria,3Y9DG@57723|Acidobacteria	57723|Acidobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
DTH3_k127_3180338_2	452637.Oter_0679	1.061e-135	444.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH3_k127_3194183_0	406124.ACPC01000017_gene625	5.503e-70	260.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
DTH3_k127_3196986_3	1254432.SCE1572_38245	6.621e-36	153.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
DTH3_k127_3196986_0	1380391.JIAS01000012_gene4362	3.731e-109	374.0	COG3525@1|root,COG3525@2|Bacteria,1QR2G@1224|Proteobacteria,2UDYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	beta-N-acetylglucosaminidase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	NAGidase
DTH3_k127_3196986_2	649638.Trad_0164	1.324e-51	189.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH3_k127_3196986_1	714943.Mucpa_7156	1.929e-99	343.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH3_k127_3196986_4	1123508.JH636442_gene4113	1.774e-07	62.0	COG1413@1|root,COG1413@2|Bacteria,2J418@203682|Planctomycetes	203682|Planctomycetes	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_3196986_5	573370.DMR_17380	5.633e-06	53.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,2MB0F@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH3_k127_3203331_1	401053.AciPR4_2231	2.862e-68	246.0	COG3250@1|root,COG3250@2|Bacteria,3Y62S@57723|Acidobacteria,2JM9E@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_3203331_0	1288963.ADIS_1157	1.02e-261	829.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3231447_0	452637.Oter_2196	3.785e-149	486.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_3231447_2	1403819.BATR01000150_gene5071	1.08e-101	350.0	COG1570@1|root,COG1570@2|Bacteria,46SCN@74201|Verrucomicrobia,2ITK4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
DTH3_k127_3231447_4	278957.ABEA03000201_gene4321	0.0005212	51.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
DTH3_k127_3231447_3	278957.ABEA03000186_gene1551	5.727e-13	72.0	COG1722@1|root,COG1722@2|Bacteria,46TB2@74201|Verrucomicrobia,3K8ES@414999|Opitutae	414999|Opitutae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
DTH3_k127_3231447_1	1156937.MFUM_270006	2.985e-118	388.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,37G36@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
DTH3_k127_3235257_0	65093.PCC7418_0570	6.515e-117	408.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Pesticin,RHS_repeat
DTH3_k127_3237348_2	240016.ABIZ01000001_gene3465	1.193e-32	140.0	COG0470@1|root,COG0470@2|Bacteria,46T6T@74201|Verrucomicrobia,2IU8J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
DTH3_k127_3237348_1	489825.LYNGBM3L_17040	4.804e-49	188.0	COG1266@1|root,COG1266@2|Bacteria,1G5HB@1117|Cyanobacteria,1HAXC@1150|Oscillatoriales	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DTH3_k127_3237348_0	1403819.BATR01000002_gene28	2.772e-155	501.0	COG1253@1|root,COG1253@2|Bacteria,46U7J@74201|Verrucomicrobia,2IVE3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DTH3_k127_3237348_3	932677.PAJ_0981	6.841e-05	50.0	2ARNE@1|root,31GZ4@2|Bacteria,1QENI@1224|Proteobacteria,1SIDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3262008_2	324602.Caur_0299	7.987e-12	75.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
DTH3_k127_3262008_1	1123247.AUIJ01000005_gene313	1.237e-29	131.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH3_k127_3262008_0	497964.CfE428DRAFT_2729	2.045e-73	257.0	COG1209@1|root,COG1209@2|Bacteria,46T9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Nucleotidyl transferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH3_k127_3262084_2	1303518.CCALI_00393	9.737e-154	497.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DUF1080,DUF4241
DTH3_k127_3262084_1	1123242.JH636434_gene4648	2.944e-175	562.0	COG0673@1|root,COG0673@2|Bacteria,2IXDR@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_3262084_3	886293.Sinac_4629	1.094e-142	469.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_3262084_4	497964.CfE428DRAFT_3384	7.507e-137	438.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DTH3_k127_3262084_0	1380394.JADL01000003_gene4962	2.553e-177	582.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
DTH3_k127_3266042_1	292459.STH3016	6.464e-93	319.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DTH3_k127_3266042_2	1123242.JH636435_gene830	3.238e-13	79.0	COG2165@1|root,COG2165@2|Bacteria,2J4W1@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_3266042_0	1123242.JH636434_gene5136	1.144e-246	775.0	COG1960@1|root,COG1960@2|Bacteria,2IXMD@203682|Planctomycetes	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DTH3_k127_3267656_1	478741.JAFS01000002_gene127	9.064e-102	348.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,37G6E@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH3_k127_3267656_0	1121012.AUKX01000029_gene941	3.882e-130	437.0	COG4409@1|root,COG4409@2|Bacteria,4PKIP@976|Bacteroidetes,1IJA8@117743|Flavobacteriia,23HZ9@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_3267656_3	929703.KE386491_gene2889	9.118e-56	201.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
DTH3_k127_3267656_2	1410653.JHVC01000018_gene2284	2.521e-96	329.0	COG1404@1|root,COG1404@2|Bacteria,1VD5C@1239|Firmicutes,24C2E@186801|Clostridia,36H8D@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH3_k127_3286066_0	926550.CLDAP_39920	2.459e-08	68.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
DTH3_k127_3288313_2	1116369.KB890025_gene5283	4.816e-113	379.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,43GYK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
DTH3_k127_3288313_0	635013.TherJR_0057	2.449e-158	514.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
DTH3_k127_3288313_5	1380394.JADL01000001_gene2442	5.993e-58	217.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH3_k127_3288313_4	1121106.JQKB01000007_gene972	5.098e-77	265.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2JPSB@204441|Rhodospirillales	204441|Rhodospirillales	C	Electron transfer flavoprotein, beta subunit	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DTH3_k127_3288313_3	1123242.JH636434_gene5139	2.103e-93	318.0	COG2025@1|root,COG2025@2|Bacteria,2J3Y1@203682|Planctomycetes	203682|Planctomycetes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
DTH3_k127_3288313_1	1125973.JNLC01000011_gene481	1.344e-129	425.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH3_k127_3311930_1	204669.Acid345_3430	1.27e-23	102.0	COG0673@1|root,COG0673@2|Bacteria,3Y3FR@57723|Acidobacteria,2JKWF@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_3311930_0	595460.RRSWK_04532	1.15e-186	591.0	COG0673@1|root,COG0673@2|Bacteria,2IXPT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_3311930_3	326427.Cagg_1390	5.4e-09	63.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH3_k127_3312380_0	1123508.JH636439_gene1348	2.082e-91	315.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG3794@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3794@2|Bacteria,2IX6X@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
DTH3_k127_3312380_1	1463936.JOJI01000044_gene7868	1.763e-38	156.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DTH3_k127_3312380_2	856793.MICA_1644	1.055e-09	72.0	COG1520@1|root,COG3533@1|root,COG1520@2|Bacteria,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,DUF4832,Laminin_G_3,PQQ_2,PQQ_3
DTH3_k127_3343707_1	234267.Acid_7735	1.225e-84	284.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH3_k127_3343707_2	706587.Desti_0559	8.246e-35	143.0	COG1225@1|root,COG1225@2|Bacteria,1NZF4@1224|Proteobacteria,42ZRX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3343707_0	293826.Amet_3280	5.739e-184	586.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,36F9T@31979|Clostridiaceae	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH3_k127_3349761_0	344747.PM8797T_25701	3.816e-156	501.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH3_k127_3349761_1	543728.Vapar_4636	9.723e-107	355.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VM9V@28216|Betaproteobacteria,4ADDA@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Periplasmic binding protein LacI transcriptional regulator	rbsB2	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
DTH3_k127_3349761_2	1123487.KB892834_gene3009	6.463e-98	329.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2WH7G@28216|Betaproteobacteria,2KZQT@206389|Rhodocyclales	28216|Betaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
DTH3_k127_3349761_3	1123248.KB893329_gene4465	4.477e-90	307.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,1IUX3@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DTH3_k127_3349761_4	102125.Xen7305DRAFT_00019380	1.309e-32	131.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
DTH3_k127_3357179_0	1396141.BATP01000040_gene2165	5.645e-151	513.0	COG2312@1|root,COG4870@1|root,COG5337@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,COG5337@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,Erythro_esteras,LTD,Peptidase_C1
DTH3_k127_3369981_2	1121405.dsmv_2973	5.117e-07	56.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WJHD@28221|Deltaproteobacteria,2MJ10@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase DHPS	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DTH3_k127_3369981_0	452637.Oter_4335	9.459e-131	436.0	COG0685@1|root,COG0685@2|Bacteria,46TD1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Methylene-tetrahydrofolate reductase C terminal	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
DTH3_k127_3369981_1	697284.ERIC2_c22790	1.401e-09	63.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,26QGM@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine	yitJ	-	1.5.1.20,2.1.1.10,2.1.1.5	ko:K00297,ko:K00544,ko:K00547	ko00260,ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00260,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R02821,R07168	RC00003,RC00035,RC00081,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
DTH3_k127_338265_1	452637.Oter_0798	2.967e-52	197.0	COG0741@1|root,COG0741@2|Bacteria,46XU1@74201|Verrucomicrobia,3K83P@414999|Opitutae	414999|Opitutae	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SLT
DTH3_k127_338265_0	497964.CfE428DRAFT_4115	1.327e-87	301.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
DTH3_k127_340519_4	1267535.KB906767_gene933	0.0003341	44.0	COG3669@1|root,COG3669@2|Bacteria,3Y37T@57723|Acidobacteria,2JKVF@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH3_k127_340519_1	240016.ABIZ01000001_gene2328	3.208e-124	411.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DTH3_k127_340519_2	452637.Oter_2441	6.927e-60	216.0	COG0284@1|root,COG0284@2|Bacteria,46T17@74201|Verrucomicrobia,3K7VT@414999|Opitutae	414999|Opitutae	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DTH3_k127_340519_0	1156937.MFUM_920003	5.383e-145	472.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,37GCZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_340519_3	497964.CfE428DRAFT_3286	8.337e-43	176.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3413373_2	936154.STP_1609	0.0007783	46.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1VDKY@1239|Firmicutes,4IS6B@91061|Bacilli	91061|Bacilli	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
DTH3_k127_3413373_0	1379698.RBG1_1C00001G1377	1.397e-34	153.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
DTH3_k127_3413373_1	794903.OPIT5_05990	4.069e-18	93.0	COG2165@1|root,COG2165@2|Bacteria,46YG4@74201|Verrucomicrobia,3K9HT@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_3419338_0	1279009.ADICEAN_01670	3.348e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
DTH3_k127_3419338_2	1125701.HMPREF1221_01616	1.115e-48	192.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3419338_1	1242864.D187_003640	3.359e-54	199.0	COG3055@1|root,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
DTH3_k127_3419727_0	1122223.KB890700_gene1996	7.329e-114	377.0	COG0687@1|root,COG0687@2|Bacteria,1WIRI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
DTH3_k127_3419727_1	321332.CYB_2209	1.248e-85	295.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria,1H1XK@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
DTH3_k127_3419727_2	670487.Ocepr_0990	1.838e-11	64.0	COG1176@1|root,COG1176@2|Bacteria,1WIWI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
DTH3_k127_3419791_1	330214.NIDE3078	2.409e-23	108.0	COG1514@1|root,COG1514@2|Bacteria,3J1B8@40117|Nitrospirae	40117|Nitrospirae	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DTH3_k127_3419791_0	497964.CfE428DRAFT_2614	2.052e-64	225.0	COG4989@1|root,COG4989@2|Bacteria,46SU2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH3_k127_3426189_1	794903.OPIT5_23075	8.095e-13	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_3426189_0	452637.Oter_1502	1.402e-72	253.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,3K7BH@414999|Opitutae	2|Bacteria	V	PFAM ABC transporter related	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_3436922_0	316067.Geob_2894	1.548e-119	392.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,43TS7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
DTH3_k127_3436922_2	1304872.JAGC01000005_gene2041	4.908e-72	259.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42NHG@68525|delta/epsilon subdivisions,2WKFP@28221|Deltaproteobacteria,2M7SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
DTH3_k127_3436922_4	1499967.BAYZ01000089_gene5033	1.045e-52	197.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH3_k127_3436922_5	1396418.BATQ01000046_gene6161	3.968e-41	164.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH3_k127_3436922_1	1303518.CCALI_00781	4.474e-73	258.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE_1	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH3_k127_3436922_3	1303518.CCALI_00782	1.275e-54	201.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
DTH3_k127_3444383_5	1229487.AMYW01000032_gene3041	4.269e-06	61.0	COG1361@1|root,COG3210@1|root,COG3291@1|root,COG4932@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium	976|Bacteroidetes	M	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SprB
DTH3_k127_3444383_4	1122609.AUGT01000002_gene3860	9.069e-08	66.0	COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria,2GJEW@201174|Actinobacteria,4DPZQ@85009|Propionibacteriales	201174|Actinobacteria	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M4,Peptidase_M4_C
DTH3_k127_3444383_1	1396141.BATP01000028_gene2285	2.17e-24	121.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
DTH3_k127_3444383_2	27923.ML204429a-PA	1.43e-17	99.0	2CMMP@1|root,2QQVA@2759|Eukaryota,38DQG@33154|Opisthokonta,3BC84@33208|Metazoa	33208|Metazoa	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH3_k127_3444383_3	177437.HRM2_06590	2.11e-14	79.0	COG0399@1|root,COG0399@2|Bacteria,1PRVB@1224|Proteobacteria,431RA@68525|delta/epsilon subdivisions,2X518@28221|Deltaproteobacteria,2MP3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
DTH3_k127_3444383_6	767817.Desgi_1747	0.0001278	45.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp,Zn_Tnp_IS91
DTH3_k127_3444383_0	999419.HMPREF1077_00773	2.954e-126	417.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,2FTQH@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_3467022_0	1396418.BATQ01000014_gene4352	1.511e-152	490.0	COG3616@1|root,COG3616@2|Bacteria,46TAP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
DTH3_k127_3467022_3	522373.Smlt0682	3.008e-11	74.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1X5BZ@135614|Xanthomonadales	135614|Xanthomonadales	G	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Calx-beta,Glyco_hydro_18,fn3
DTH3_k127_3467022_2	316274.Haur_2251	4.158e-31	144.0	COG1629@1|root,COG3055@1|root,COG1629@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Kelch_1,Plug
DTH3_k127_3467022_1	452637.Oter_0135	5.094e-65	226.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
DTH3_k127_3472287_2	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
DTH3_k127_3472287_1	909663.KI867150_gene711	3.617e-66	236.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,43A29@68525|delta/epsilon subdivisions,2X21K@28221|Deltaproteobacteria,2MS4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
DTH3_k127_3472287_0	478741.JAFS01000002_gene146	3.257e-141	478.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,37FVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	tail specific protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
DTH3_k127_3499129_10	382464.ABSI01000013_gene1669	2.109e-35	149.0	COG0643@1|root,COG0643@2|Bacteria,46UEP@74201|Verrucomicrobia,2IUVS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
DTH3_k127_3499129_6	1123258.AQXZ01000016_gene2259	1.094e-53	199.0	COG3675@1|root,COG3675@2|Bacteria,2HK7P@201174|Actinobacteria,4G7ZK@85025|Nocardiaceae	201174|Actinobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
DTH3_k127_3499129_13	243233.MCA2757	6.547e-14	76.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
DTH3_k127_3499129_8	243233.MCA2757	1.784e-48	186.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
DTH3_k127_3499129_2	323848.Nmul_A0761	1.507e-168	542.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,2VR1P@28216|Betaproteobacteria,371Z3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3,PP-binding
DTH3_k127_3499129_1	478741.JAFS01000001_gene2129	1.35e-191	624.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,37FUI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
DTH3_k127_3499129_4	1396141.BATP01000047_gene3937	2.878e-112	370.0	COG0005@1|root,COG0005@2|Bacteria,46UP8@74201|Verrucomicrobia,2ITPF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
DTH3_k127_3499129_7	313606.M23134_03514	7.81e-52	191.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
DTH3_k127_3499129_12	1356852.N008_20380	4.096e-24	109.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
DTH3_k127_3499129_3	1121930.AQXG01000002_gene2269	1.073e-161	522.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
DTH3_k127_3499129_9	1191523.MROS_1515	1.13e-45	171.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
DTH3_k127_3499129_0	1191523.MROS_1513	0.0	1074.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	ccoO	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.9.3.1	ko:K00404,ko:K00405,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144,iIT341.HP0145	COX1,FixO
DTH3_k127_3499129_14	1313301.AUGC01000014_gene2496	6.821e-08	57.0	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
DTH3_k127_3499129_5	945713.IALB_0720	4.981e-111	381.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
DTH3_k127_3514393_0	547042.BACCOPRO_00511	7.751e-44	178.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,2FR8R@200643|Bacteroidia,4AQA2@815|Bacteroidaceae	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH3_k127_3514393_1	1502850.FG91_00796	5.003e-07	63.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales	204457|Sphingomonadales	QU	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
DTH3_k127_3537581_6	1396141.BATP01000038_gene1208	1.934e-56	203.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH3_k127_3537581_4	1396141.BATP01000038_gene1209	2.805e-138	446.0	COG1879@1|root,COG1879@2|Bacteria,46XDV@74201|Verrucomicrobia,2IVKX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
DTH3_k127_3537581_3	1185876.BN8_00694	1.133e-139	455.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
DTH3_k127_3537581_5	1235797.C816_02559	2.753e-92	310.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,2N6GG@216572|Oscillospiraceae	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
DTH3_k127_3537581_0	518766.Rmar_0469	2.523e-231	728.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
DTH3_k127_3537581_2	926550.CLDAP_13620	6.713e-144	467.0	COG1063@1|root,COG1063@2|Bacteria,2G7MF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
DTH3_k127_3537581_1	661478.OP10G_1294	1.059e-152	501.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
DTH3_k127_3542236_2	258594.RPA3925	1.586e-41	156.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,3JRQ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46,4.2.1.76,5.1.3.2	ko:K01710,ko:K01784,ko:K12450	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00293,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH3_k127_3542236_5	481448.Minf_2165	3.663e-12	75.0	2FHDV@1|root,34981@2|Bacteria,46W9B@74201|Verrucomicrobia,37GRP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3542236_4	1118054.CAGW01000014_gene225	4.437e-29	126.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,26XF4@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	adaB	-	2.1.1.63	ko:K00567,ko:K10778,ko:K13531	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DTH3_k127_3542236_1	452637.Oter_1562	4.803e-109	368.0	COG2271@1|root,COG2271@2|Bacteria,46W2G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Major Facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
DTH3_k127_3542236_6	278957.ABEA03000069_gene3974	5.156e-05	53.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_3542236_0	1403819.BATR01000181_gene6235	1.933e-182	580.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,2ITSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	S4,tRNA-synt_1b
DTH3_k127_3542236_3	1173023.KE650771_gene4898	6.037e-39	160.0	COG1749@1|root,COG3525@1|root,COG1749@2|Bacteria,COG3525@2|Bacteria,1GBDW@1117|Cyanobacteria	1117|Cyanobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082
DTH3_k127_3569214_1	504472.Slin_2796	1.218e-48	179.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH3_k127_3569214_0	1396141.BATP01000003_gene5218	2.995e-74	260.0	COG2503@1|root,COG2503@2|Bacteria,46U63@74201|Verrucomicrobia	74201|Verrucomicrobia	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3569214_2	575540.Isop_2812	1.726e-18	86.0	COG0673@1|root,COG0673@2|Bacteria,2IX34@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_3578598_2	240016.ABIZ01000001_gene2202	2.472e-35	138.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
DTH3_k127_3578598_0	211165.AJLN01000098_gene5214	1.648e-127	423.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1JKCQ@1189|Stigonemataceae	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
DTH3_k127_3578598_4	871585.BDGL_001653	3.698e-05	55.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1S5BT@1236|Gammaproteobacteria,3NK23@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
DTH3_k127_3578598_1	497964.CfE428DRAFT_0566	2.672e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
DTH3_k127_3578598_3	290397.Adeh_3736	1.758e-10	66.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
DTH3_k127_3587388_0	234267.Acid_7405	1.573e-62	225.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
DTH3_k127_3587388_1	1396418.BATQ01000078_gene616	0.0008571	51.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	SLH
DTH3_k127_3590686_2	177437.HRM2_38050	2.063e-138	448.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DTH3_k127_3590686_0	497964.CfE428DRAFT_0990	4.606e-262	827.0	COG0514@1|root,COG0514@2|Bacteria,46S7V@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
DTH3_k127_3590686_1	1121438.JNJA01000001_gene2267	1.48e-223	714.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
DTH3_k127_3590686_4	497964.CfE428DRAFT_1901	4.068e-29	119.0	COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH3_k127_3590686_3	349741.Amuc_1327	4.541e-75	258.0	COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,2ITS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH3_k127_3591451_0	1121920.AUAU01000024_gene2386	8.438e-91	304.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DTH3_k127_3591451_2	1121920.AUAU01000024_gene2384	1.677e-74	275.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
DTH3_k127_3591451_1	1121920.AUAU01000024_gene2382	2.187e-88	305.0	COG3303@1|root,COG4733@1|root,COG3303@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Big_2,DUF285,HYR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N,Paired_CXXCH_1,SLH,fn3
DTH3_k127_3600907_0	452637.Oter_2583	1.399e-82	282.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH3_k127_3600907_5	497964.CfE428DRAFT_3521	7.476e-28	132.0	COG2010@1|root,COG2010@2|Bacteria,46TD5@74201|Verrucomicrobia	2|Bacteria	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
DTH3_k127_3600907_7	1089545.KB913037_gene8972	1.017e-06	58.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
DTH3_k127_3600907_6	1189620.AJXL01000002_gene1866	6.668e-19	95.0	COG2032@1|root,COG2032@2|Bacteria,4NGGW@976|Bacteroidetes,1HY8P@117743|Flavobacteriia,2NYDV@237|Flavobacterium	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
DTH3_k127_3600907_3	1121422.AUMW01000010_gene1055	9.15e-48	180.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DTH3_k127_3600907_4	1535422.ND16A_0876	4.616e-31	136.0	COG0652@1|root,COG0652@2|Bacteria,1RCXX@1224|Proteobacteria,1S3ZN@1236|Gammaproteobacteria,2Q751@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DTH3_k127_3600907_1	497964.CfE428DRAFT_4164	1.077e-66	237.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DTH3_k127_3600907_2	1459636.NTE_02269	3.425e-50	185.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
DTH3_k127_3607411_3	661478.OP10G_2899	1.883e-32	141.0	COG2730@1|root,COG3291@1|root,COG2730@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase,PA14
DTH3_k127_3607411_1	1396141.BATP01000002_gene4845	2.762e-58	213.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_3607411_0	1396141.BATP01000002_gene4846	8.567e-84	302.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
DTH3_k127_3607411_4	864051.BurJ1DRAFT_3700	3.098e-17	96.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
DTH3_k127_3607411_5	278957.ABEA03000106_gene1817	1.407e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3607411_2	595460.RRSWK_01659	1.294e-38	156.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH3_k127_3615963_1	886293.Sinac_0400	5.201e-11	73.0	COG4249@1|root,COG4249@2|Bacteria,2IZ2A@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3615963_0	886293.Sinac_0401	6.137e-209	671.0	COG5426@1|root,COG5426@2|Bacteria,2IWWQ@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
DTH3_k127_3626366_2	1123401.JHYQ01000003_gene2070	5.348e-31	143.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH3_k127_3626366_1	478741.JAFS01000002_gene501	1.166e-47	188.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
DTH3_k127_3626366_0	1379698.RBG1_1C00001G1529	3.644e-99	340.0	COG2304@1|root,COG2304@2|Bacteria,2NPUS@2323|unclassified Bacteria	2|Bacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
DTH3_k127_3626366_3	1210884.HG799466_gene12939	4.215e-09	63.0	COG1404@1|root,COG3210@1|root,COG3291@1|root,COG4254@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4254@2|Bacteria,2J50K@203682|Planctomycetes	203682|Planctomycetes	U	Pkd domain containing protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	-
DTH3_k127_3628996_0	344747.PM8797T_25811	1.553e-74	257.0	COG2609@1|root,COG2609@2|Bacteria,2IXXY@203682|Planctomycetes	203682|Planctomycetes	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DTH3_k127_3628996_1	479434.Sthe_2682	1.035e-71	256.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
DTH3_k127_3628996_2	525897.Dbac_1874	3.056e-05	57.0	COG0457@1|root,COG0790@1|root,COG3914@1|root,COG0457@2|Bacteria,COG0790@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,2MCDQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
DTH3_k127_3631557_5	880073.Calab_0118	3.699e-24	118.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.89	ko:K01224,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DctA-YdbH,Laminin_G_3
DTH3_k127_3631557_4	7739.XP_002608621.1	2.14e-26	125.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTYV@33213|Bilateria,47YVC@7711|Chordata	33208|Metazoa	T	positive regulation of presynaptic membrane organization	LRP4	GO:0000902,GO:0000904,GO:0001655,GO:0001822,GO:0001932,GO:0001934,GO:0001941,GO:0001942,GO:0003002,GO:0003674,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007389,GO:0007399,GO:0007416,GO:0007528,GO:0008104,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009893,GO:0009950,GO:0009953,GO:0009954,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010648,GO:0010721,GO:0010769,GO:0010771,GO:0010975,GO:0010977,GO:0014069,GO:0016020,GO:0016043,GO:0016055,GO:0016358,GO:0017147,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022404,GO:0022405,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030278,GO:0030279,GO:0030326,GO:0030424,GO:0030425,GO:0030971,GO:0031175,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031399,GO:0031401,GO:0031594,GO:0032268,GO:0032270,GO:0032279,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034185,GO:0034613,GO:0035107,GO:0035108,GO:0035113,GO:0036477,GO:0038023,GO:0040007,GO:0042303,GO:0042325,GO:0042327,GO:0042475,GO:0042476,GO:0042633,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042995,GO:0043005,GO:0043025,GO:0043113,GO:0043226,GO:0043235,GO:0043588,GO:0043679,GO:0043933,GO:0044085,GO:0044091,GO:0044297,GO:0044306,GO:0044332,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045937,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048736,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050770,GO:0050771,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051093,GO:0051124,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051641,GO:0051668,GO:0051716,GO:0051960,GO:0051961,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060828,GO:0061024,GO:0065003,GO:0065007,GO:0065008,GO:0070727,GO:0071340,GO:0071709,GO:0071840,GO:0071944,GO:0072001,GO:0072657,GO:0080090,GO:0090090,GO:0097060,GO:0097090,GO:0097104,GO:0097105,GO:0097110,GO:0097447,GO:0097458,GO:0098590,GO:0098773,GO:0098793,GO:0098794,GO:0098984,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099175,GO:0099572,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:0198738,GO:1901626,GO:1901628,GO:1901629,GO:1901631,GO:1903827,GO:1903829,GO:1903909,GO:1903911,GO:1904393,GO:1904395,GO:1904396,GO:1904398,GO:1905114,GO:1905475,GO:1905477,GO:1990709,GO:1990782,GO:2000026	-	ko:K20051	-	-	-	-	ko00000,ko04131	-	-	-	EGF_CA,FXa_inhibition,Ldl_recept_a,Ldl_recept_b,cEGF
DTH3_k127_3631557_1	768671.ThimaDRAFT_3684	9.962e-94	316.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,1RPJM@1236|Gammaproteobacteria,1WYYP@135613|Chromatiales	135613|Chromatiales	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
DTH3_k127_3631557_0	1121405.dsmv_0890	1.429e-174	562.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MIDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein)	-	-	-	-	-	-	-	-	-	-	-	-	rve
DTH3_k127_3631557_3	555779.Dthio_PD3610	1.061e-30	126.0	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3631557_2	218284.CCDN010000001_gene723	3.367e-32	143.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
DTH3_k127_3640012_0	530564.Psta_1492	2.895e-133	446.0	COG1053@1|root,COG1053@2|Bacteria,2J4ZP@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH3_k127_3640012_1	1123278.KB893597_gene2721	9.592e-125	421.0	COG1621@1|root,COG1621@2|Bacteria,4NJ8X@976|Bacteroidetes,47N6D@768503|Cytophagia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
DTH3_k127_3640012_2	869213.JCM21142_93751	7.604e-46	172.0	COG2273@1|root,COG2273@2|Bacteria,4P0F6@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
DTH3_k127_365278_2	1396141.BATP01000023_gene643	6.249e-126	409.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,2ITHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH3_k127_365278_6	886293.Sinac_0868	6.776e-38	149.0	COG5507@1|root,COG5507@2|Bacteria,2J071@203682|Planctomycetes	203682|Planctomycetes	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
DTH3_k127_365278_0	497964.CfE428DRAFT_2099	1.669e-201	647.0	COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DTH3_k127_365278_3	497964.CfE428DRAFT_1492	5.613e-90	300.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH3_k127_365278_4	1123376.AUIU01000011_gene924	1.047e-62	222.0	COG0118@1|root,COG0118@2|Bacteria,3J0K7@40117|Nitrospirae	40117|Nitrospirae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DTH3_k127_365278_1	497964.CfE428DRAFT_0899	1.69e-126	416.0	COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
DTH3_k127_365278_5	313603.FB2170_14633	3.548e-39	152.0	COG1082@1|root,COG1082@2|Bacteria,4NFSP@976|Bacteroidetes,1HZ9M@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_3653355_3	1218084.BBJK01000086_gene5778	9.72e-06	58.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
DTH3_k127_3653355_0	644966.Tmar_0705	3.278e-154	505.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,24BT1@186801|Clostridia,3WD7J@538999|Clostridiales incertae sedis	186801|Clostridia	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DTH3_k127_3653355_1	1123242.JH636434_gene4911	3.463e-130	429.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH3_k127_3653355_2	1123008.KB905693_gene1177	2.859e-113	372.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes	976|Bacteroidetes	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
DTH3_k127_3656173_2	380703.AHA_0030	3.737e-89	303.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
DTH3_k127_3656173_0	1499967.BAYZ01000182_gene4442	1.782e-118	389.0	COG0673@1|root,COG0673@2|Bacteria,2NQJN@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_3656173_1	926550.CLDAP_26140	5.316e-109	358.0	COG1082@1|root,COG1082@2|Bacteria,2G613@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_3660568_1	1121456.ATVA01000014_gene568	1.281e-75	270.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2M9FY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
DTH3_k127_3660568_0	945713.IALB_0983	1.454e-99	338.0	COG4299@1|root,COG4299@2|Bacteria	2|Bacteria	G	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
DTH3_k127_3660568_2	794903.OPIT5_15450	3.985e-19	96.0	COG2165@1|root,COG2165@2|Bacteria,46XJA@74201|Verrucomicrobia,3K9FD@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH3_k127_3662585_8	497964.CfE428DRAFT_2195	2.421e-13	75.0	COG3271@1|root,COG3271@2|Bacteria,46VSC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase C39 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
DTH3_k127_3662585_0	497964.CfE428DRAFT_5133	2.911e-285	885.0	COG1164@1|root,COG1164@2|Bacteria,46UYB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
DTH3_k127_3662585_3	156889.Mmc1_0977	1.376e-78	273.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
DTH3_k127_3662585_2	1304885.AUEY01000001_gene3217	6.793e-105	357.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_3662585_7	1329516.JPST01000035_gene3088	4.6e-39	158.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,27BT7@186824|Thermoactinomycetaceae	91061|Bacilli	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
DTH3_k127_3662585_6	497964.CfE428DRAFT_4165	2.982e-56	200.0	COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
DTH3_k127_3662585_5	1396141.BATP01000003_gene5267	2.723e-66	229.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
DTH3_k127_3662585_1	452637.Oter_2356	1.964e-112	373.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,3K7U5@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DTH3_k127_3662585_4	452637.Oter_3509	4.978e-70	247.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_3687046_2	452637.Oter_2196	4.882e-191	606.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_3687046_1	502025.Hoch_2528	1.363e-309	983.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DTH3_k127_3687046_0	502025.Hoch_2529	0.0	1187.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DTH3_k127_3687046_3	502025.Hoch_2530	1.136e-74	265.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42MPE@68525|delta/epsilon subdivisions,2X630@28221|Deltaproteobacteria,2Z38I@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH3_k127_3687858_0	886293.Sinac_6980	6.133e-150	489.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_3687858_2	234267.Acid_6615	5.612e-17	93.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3687858_1	679935.Alfi_1534	7.165e-85	304.0	COG0204@1|root,COG2813@1|root,COG4258@1|root,COG0204@2|Bacteria,COG2813@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,2FQP4@200643|Bacteroidia	976|Bacteroidetes	I	Acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
DTH3_k127_3689954_1	1396418.BATQ01000133_gene4024	1.214e-69	241.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
DTH3_k127_3689954_0	497964.CfE428DRAFT_5147	4.476e-122	412.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DTH3_k127_3689954_2	497964.CfE428DRAFT_5146	3.962e-68	237.0	COG1541@1|root,COG1541@2|Bacteria,46UTU@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
DTH3_k127_3733370_3	929713.NIASO_12720	1.964e-33	132.0	2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,1IQ38@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_3733370_0	234267.Acid_3343	1.726e-156	510.0	COG4948@1|root,COG4948@2|Bacteria,3Y61U@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
DTH3_k127_3733370_2	1121875.KB907555_gene345	1.49e-83	292.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia	976|Bacteroidetes	S	Sodium bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
DTH3_k127_3733370_1	314230.DSM3645_21427	1.356e-86	294.0	COG1387@1|root,COG2755@1|root,COG1387@2|Bacteria,COG2755@2|Bacteria,2IXFZ@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_3744608_2	251229.Chro_4403	3.151e-121	402.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,3VI6E@52604|Pleurocapsales	1117|Cyanobacteria	O	PFAM HypF finger	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
DTH3_k127_3744608_6	518766.Rmar_2594	1.395e-27	113.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes	976|Bacteroidetes	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
DTH3_k127_3744608_0	204669.Acid345_1705	2.121e-178	568.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia	204432|Acidobacteriia	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
DTH3_k127_3744608_1	56110.Oscil6304_5908	9.256e-149	479.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1H82T@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
DTH3_k127_3744608_7	313628.LNTAR_17808	2.324e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_3744608_3	234267.Acid_5336	3.046e-120	424.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,3Y3IC@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
DTH3_k127_3744608_8	177437.HRM2_37840	1.142e-05	55.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NWT@68525|delta/epsilon subdivisions,2X5DA@28221|Deltaproteobacteria,2MMYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_3744608_5	497964.CfE428DRAFT_2826	1.244e-61	219.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_3744608_4	497964.CfE428DRAFT_2825	9.506e-98	355.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46TEF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Von Willebrand factor	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,VWA_3,vWF_A
DTH3_k127_3745140_4	497964.CfE428DRAFT_3097	2.502e-15	78.0	COG1510@1|root,COG1510@2|Bacteria,46VTX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3745140_2	497964.CfE428DRAFT_4863	1.348e-103	376.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3745140_3	497964.CfE428DRAFT_4864	9.767e-66	237.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3745140_1	1217720.ALOX01000026_gene3512	1.78e-138	455.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPSC@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_3745140_0	1403819.BATR01000107_gene3655	1.455e-173	555.0	COG0277@1|root,COG0277@2|Bacteria,46S85@74201|Verrucomicrobia,2IVC9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
DTH3_k127_3748508_0	452637.Oter_0670	6.626e-214	670.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH3_k127_3748508_1	583355.Caka_1740	3.076e-46	177.0	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
DTH3_k127_3748508_3	1125863.JAFN01000001_gene2910	3.949e-34	139.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
DTH3_k127_3748508_2	1173024.KI912148_gene4571	1.168e-36	139.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1JMTM@1189|Stigonemataceae	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH3_k127_3750521_2	880073.Calab_1259	9.139e-21	100.0	COG1538@1|root,COG1538@2|Bacteria,2NS0Y@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
DTH3_k127_3750521_1	886293.Sinac_3363	6.502e-26	120.0	COG4299@1|root,COG4299@2|Bacteria,2IYKU@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DTH3_k127_3750521_0	309807.SRU_2450	1.278e-90	318.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1FIWB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
DTH3_k127_3753213_0	439235.Dalk_1463	5.009e-77	269.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
DTH3_k127_3764458_1	794903.OPIT5_29980	2.031e-35	148.0	2EX0Y@1|root,33QC4@2|Bacteria,46UUA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3764458_0	472759.Nhal_1137	1.568e-40	152.0	COG1403@1|root,COG1403@2|Bacteria,1N6FJ@1224|Proteobacteria	1224|Proteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3764458_2	497964.CfE428DRAFT_1301	1.696e-23	105.0	COG3598@1|root,COG3598@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	ko:K07505	-	-	-	-	ko00000	-	-	-	AAA_25,PriCT_2
DTH3_k127_3768932_1	497964.CfE428DRAFT_1407	3.294e-26	115.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
DTH3_k127_3768932_0	717605.Theco_3395	1.397e-29	133.0	COG2931@1|root,COG2931@2|Bacteria,1V022@1239|Firmicutes,4HFJ6@91061|Bacilli,26SF3@186822|Paenibacillaceae	91061|Bacilli	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH3_k127_3768932_2	1408473.JHXO01000009_gene3340	5.47e-17	85.0	2DR6U@1|root,33AFB@2|Bacteria,4P5F6@976|Bacteroidetes,2FYZD@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_379445_0	497964.CfE428DRAFT_3048	3.817e-147	469.0	COG1879@1|root,COG1879@2|Bacteria,46TWY@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
DTH3_k127_379445_4	886293.Sinac_0846	8.822e-63	228.0	COG0310@1|root,COG0310@2|Bacteria,2IZTS@203682|Planctomycetes	203682|Planctomycetes	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
DTH3_k127_379445_5	675635.Psed_3353	8.258e-22	103.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria,4E0T6@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
DTH3_k127_379445_3	886293.Sinac_0844	1.294e-73	255.0	COG1122@1|root,COG1122@2|Bacteria,2IZ47@203682|Planctomycetes	203682|Planctomycetes	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
DTH3_k127_379445_2	452637.Oter_1576	8.09e-86	295.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,3K7J8@414999|Opitutae	414999|Opitutae	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DTH3_k127_379445_1	478741.JAFS01000002_gene392	3.129e-92	317.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia,37FXN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	PAS domain	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
DTH3_k127_379445_6	1403819.BATR01000181_gene6054	7.948e-11	67.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DTH3_k127_3794887_0	886293.Sinac_5714	5.561e-162	526.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYA8@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_3794887_1	448385.sce7786	7.355e-134	440.0	COG3104@1|root,COG3104@2|Bacteria,1P6K2@1224|Proteobacteria	1224|Proteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_3796823_0	234267.Acid_2413	2.814e-60	217.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
DTH3_k127_3822606_5	497964.CfE428DRAFT_1483	1.495e-06	49.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH3_k127_3822606_4	497964.CfE428DRAFT_5124	5.105e-25	109.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,LytTR,PAS,PAS_3,PAS_9,Response_reg,dCache_1
DTH3_k127_3822606_0	794903.OPIT5_30480	1.668e-135	444.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
DTH3_k127_3822606_3	1042209.HK44_007325	1.478e-49	180.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DTH3_k127_3822606_2	1437824.BN940_09076	2.773e-58	208.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VPN0@28216|Betaproteobacteria,3T3HF@506|Alcaligenaceae	28216|Betaproteobacteria	S	Iron-sulfur cluster assembly protein	sufT	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH3_k127_3822606_1	1396418.BATQ01000079_gene806	1.048e-108	357.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,2IU2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DTH3_k127_3835986_4	324602.Caur_0299	2.16e-24	114.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
DTH3_k127_3835986_3	926569.ANT_03070	1.897e-26	128.0	COG5295@1|root,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3835986_0	760192.Halhy_1406	7.925e-145	471.0	COG0673@1|root,COG0673@2|Bacteria,4NENY@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_3835986_1	349521.HCH_05643	3.331e-60	228.0	COG3209@1|root,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,1XMP6@135619|Oceanospirillales	135619|Oceanospirillales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
DTH3_k127_3838741_0	886293.Sinac_7009	1.503e-304	950.0	COG2010@1|root,COG2010@2|Bacteria,2IY6K@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_3838741_1	886293.Sinac_7008	3.687e-179	566.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_3846137_0	671143.DAMO_0966	1.172e-105	353.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
DTH3_k127_3846137_2	522306.CAP2UW1_1318	5.844e-87	298.0	COG3597@1|root,COG3597@2|Bacteria,1QG9J@1224|Proteobacteria,2VIRR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	DUF533,TerB
DTH3_k127_3846137_3	1396141.BATP01000025_gene912	1.648e-66	237.0	COG0583@1|root,COG0583@2|Bacteria,46ZKT@74201|Verrucomicrobia,2IVKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
DTH3_k127_3846137_1	1403819.BATR01000053_gene1630	1.688e-105	346.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia,2IU6M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
DTH3_k127_3846137_4	292564.Cyagr_2618	1.124e-30	123.0	COG0778@1|root,COG0778@2|Bacteria,1G2KA@1117|Cyanobacteria,22T7B@167375|Cyanobium	1117|Cyanobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DTH3_k127_385637_1	240015.ACP_1727	7.219e-59	209.0	COG1028@1|root,COG1028@2|Bacteria	240015.ACP_1727|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_385637_2	755178.Cyan10605_1738	2.633e-23	106.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Response_reg
DTH3_k127_385637_0	1340493.JNIF01000004_gene1121	3.898e-102	339.0	COG0702@1|root,COG0702@2|Bacteria,3Y666@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
DTH3_k127_385637_3	886293.Sinac_1978	4.626e-08	58.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH3_k127_3864908_1	909663.KI867150_gene2770	1.166e-48	186.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
DTH3_k127_3864908_0	946483.Cenrod_2361	2.183e-86	304.0	COG3039@1|root,COG3039@2|Bacteria,1R6NB@1224|Proteobacteria,2W14S@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3878604_1	439235.Dalk_3988	2.676e-36	143.0	COG3809@1|root,COG3809@2|Bacteria,1QSA6@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
DTH3_k127_3878604_0	1120953.AUBH01000005_gene2232	7.02e-38	155.0	COG3595@1|root,COG3595@2|Bacteria,1RFCY@1224|Proteobacteria,1S5RB@1236|Gammaproteobacteria,467PX@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
DTH3_k127_3878604_2	1123508.JH636439_gene1132	5.78e-13	75.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
DTH3_k127_3881861_1	1174528.JH992898_gene5362	1.993e-69	238.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
DTH3_k127_3881861_4	671143.DAMO_0355	4.57e-07	55.0	COG4096@1|root,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
DTH3_k127_3881861_0	1116472.MGMO_115c00240	2.057e-110	373.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH3_k127_3881861_3	1121924.ATWH01000005_gene2605	4.189e-13	83.0	COG1874@1|root,COG1874@2|Bacteria,2H2YV@201174|Actinobacteria,4FQYV@85023|Microbacteriaceae	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3881861_2	697282.Mettu_3684	4.406e-29	120.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria,1XGMP@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3881861_5	90814.KL370891_gene1376	7.168e-06	48.0	2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria,4639K@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3905231_2	497964.CfE428DRAFT_4840	1.341e-28	116.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH3_k127_3905231_1	204536.SULAZ_0984	8.444e-106	357.0	COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
DTH3_k127_3905231_0	1396418.BATQ01000012_gene4420	1.253e-199	627.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH3_k127_3905231_6	794903.OPIT5_23755	5.622e-05	48.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DTH3_k127_3905231_5	1303518.CCALI_02308	3.081e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_3905231_4	1123508.JH636446_gene6223	4.43e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_3905231_3	449447.MAE_23460	3.474e-17	96.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
DTH3_k127_3906825_4	1144305.PMI02_01448	3.681e-08	56.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,2K1GI@204457|Sphingomonadales	204457|Sphingomonadales	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DTH3_k127_3906825_2	583355.Caka_1943	2.587e-41	158.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia,3K7WB@414999|Opitutae	414999|Opitutae	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DTH3_k127_3906825_0	240016.ABIZ01000001_gene3008	1.223e-147	480.0	COG1520@1|root,COG1520@2|Bacteria,46U6I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_3906825_1	756272.Plabr_2335	5.083e-102	347.0	COG2755@1|root,COG2755@2|Bacteria,2IYGD@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_3906825_3	1142394.PSMK_06110	9.118e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_3906825_5	357808.RoseRS_3871	9.579e-07	59.0	COG0810@1|root,COG3266@1|root,COG0810@2|Bacteria,COG3266@2|Bacteria,2G8B4@200795|Chloroflexi	200795|Chloroflexi	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH3_k127_3922455_0	926562.Oweho_0226	1.415e-40	169.0	COG0644@1|root,COG0644@2|Bacteria,4PKHH@976|Bacteroidetes,1IJ96@117743|Flavobacteriia	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH3_k127_3922455_1	1116472.MGMO_20c00250	1.825e-21	108.0	COG1020@1|root,COG1020@2|Bacteria,1NK69@1224|Proteobacteria,1SKZR@1236|Gammaproteobacteria,1XFVG@135618|Methylococcales	135618|Methylococcales	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3922455_2	1192034.CAP_6765	2.308e-05	50.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	-	ko:K21781	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002	-	-	-	PP-binding
DTH3_k127_3922455_3	196162.Noca_4116	0.000158	44.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
DTH3_k127_3924904_1	1408445.JHXP01000026_gene2302	6.607e-77	275.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,1JGK2@118969|Legionellales	118969|Legionellales	M	Beta-eliminating lyase	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
DTH3_k127_3924904_0	1200792.AKYF01000018_gene5885	3.821e-80	288.0	COG0531@1|root,COG0531@2|Bacteria,1VS5Q@1239|Firmicutes,4HTCE@91061|Bacilli,275MC@186822|Paenibacillaceae	91061|Bacilli	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
DTH3_k127_3925121_1	1403819.BATR01000125_gene4494	6.298e-76	267.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH3_k127_3925121_2	1396141.BATP01000002_gene4845	9.621e-54	196.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_3925121_0	794903.OPIT5_24610	4.363e-82	286.0	COG0657@1|root,COG0657@2|Bacteria,46UVS@74201|Verrucomicrobia	2|Bacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
DTH3_k127_3925121_3	794903.OPIT5_12525	3.03e-20	100.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_392815_0	335543.Sfum_1457	1.407e-229	731.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
DTH3_k127_392815_1	1267534.KB906756_gene11	1.786e-38	157.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
DTH3_k127_3928347_0	1396141.BATP01000019_gene1673	2.232e-127	428.0	COG5557@1|root,COG5557@2|Bacteria,46U15@74201|Verrucomicrobia,2ITS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
DTH3_k127_3936538_2	452637.Oter_4612	1.583e-18	97.0	COG5549@1|root,COG5549@2|Bacteria,46UKP@74201|Verrucomicrobia,3KA3E@414999|Opitutae	2|Bacteria	O	Immunoglobulin I-set domain protein	-	-	3.2.1.4,3.4.24.40	ko:K01179,ko:K01406	ko00500,ko01100,ko01503,map00500,map01100,map01503	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002	-	GH5,GH9	-	CBM60,DUF4214,Glyco_hydro_16,HemolysinCabind,Peptidase_M10,Peptidase_M10_C,Reprolysin_4,W_rich_C
DTH3_k127_3936538_0	378806.STAUR_6001	9.206e-88	308.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,4393J@68525|delta/epsilon subdivisions,2X49H@28221|Deltaproteobacteria,2YYJE@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_3936538_1	489825.LYNGBM3L_32100	3.634e-21	97.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH3_k127_3940017_2	1125863.JAFN01000001_gene1724	3.817e-57	208.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
DTH3_k127_3940017_0	497964.CfE428DRAFT_1506	1.42e-147	478.0	COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
DTH3_k127_3940017_1	497964.CfE428DRAFT_0797	2.754e-91	304.0	COG0060@1|root,COG0060@2|Bacteria,46SEC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
DTH3_k127_3944991_0	1134413.ANNK01000094_gene900	4.074e-69	252.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,1ZCXK@1386|Bacillus	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
DTH3_k127_3944991_3	1197130.BAFM01000020_gene2812	1.151e-20	106.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVPQ@28890|Euryarchaeota,23TTF@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_3944991_1	1116472.MGMO_10c00180	5.506e-62	221.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1XDRK@135618|Methylococcales	135618|Methylococcales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
DTH3_k127_3944991_2	316274.Haur_0795	1.476e-33	138.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,LuxE
DTH3_k127_3954984_0	485918.Cpin_1862	3.591e-129	424.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IUWM@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
DTH3_k127_3954984_1	153721.MYP_192	1.567e-101	341.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DTH3_k127_396047_0	886293.Sinac_6923	1.15e-126	409.0	COG2159@1|root,COG2159@2|Bacteria,2IZCY@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DTH3_k127_396047_1	886293.Sinac_6924	2.089e-87	299.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DTH3_k127_396047_3	697282.Mettu_1034	9.41e-45	169.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,1T0Q8@1236|Gammaproteobacteria,1XFBQ@135618|Methylococcales	135618|Methylococcales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
DTH3_k127_396047_2	517418.Ctha_0234	1.986e-48	178.0	COG1225@1|root,COG1225@2|Bacteria,1FF4E@1090|Chlorobi	1090|Chlorobi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH3_k127_3967737_0	536233.CLO_0602	1.634e-31	127.0	COG2356@1|root,COG4085@1|root,COG2356@2|Bacteria,COG4085@2|Bacteria,1UKZ5@1239|Firmicutes,24X63@186801|Clostridia,36R4U@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
DTH3_k127_3967737_2	323098.Nwi_0269	9.838e-08	55.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2TQQA@28211|Alphaproteobacteria,3JZMK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N_2,HsdM_N,N6_Mtase
DTH3_k127_3967737_1	713587.THITH_06000	4.619e-26	113.0	COG1569@1|root,COG1569@2|Bacteria,1NJ68@1224|Proteobacteria,1SAF3@1236|Gammaproteobacteria,1X17S@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
DTH3_k127_3973210_4	661087.HMPREF1008_01772	5.793e-51	189.0	COG0330@1|root,COG0330@2|Bacteria,2GM0Z@201174|Actinobacteria,4CUCE@84998|Coriobacteriia	84998|Coriobacteriia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH3_k127_3973210_0	1396141.BATP01000030_gene3783	2.038e-313	975.0	28I74@1|root,2Z8A0@2|Bacteria,46TG0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3973210_6	635013.TherJR_1799	1.891e-26	116.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
DTH3_k127_3973210_3	523841.HFX_0260	4.153e-53	200.0	COG0421@1|root,COG0477@1|root,arCOG00050@2157|Archaea,arCOG02682@2157|Archaea,2XUEJ@28890|Euryarchaeota,23T1E@183963|Halobacteria	183963|Halobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
DTH3_k127_3973210_5	671143.DAMO_0994	3.938e-29	124.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH3_k127_3973210_1	595460.RRSWK_04461	8.428e-107	353.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_3979946_2	1449050.JNLE01000005_gene4996	6.073e-27	119.0	COG2730@1|root,COG5520@1|root,COG2730@2|Bacteria,COG5520@2|Bacteria,1TS9M@1239|Firmicutes,24DA9@186801|Clostridia,36KJ1@31979|Clostridiaceae	186801|Clostridia	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Cellulase
DTH3_k127_3979946_3	1210884.HG799480_gene15519	4.175e-26	116.0	COG1387@1|root,COG1387@2|Bacteria,2IZ7D@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_3979946_0	452637.Oter_2972	6.033e-215	677.0	COG3669@1|root,COG3669@2|Bacteria,46Y1K@74201|Verrucomicrobia,3K8SP@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
DTH3_k127_3979946_1	1122931.AUAE01000028_gene113	1.148e-66	235.0	2CB8C@1|root,33T5I@2|Bacteria,4P0N1@976|Bacteroidetes,2FX4B@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_3985042_0	497964.CfE428DRAFT_2607	2.848e-127	412.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH3_k127_3985042_2	1521187.JPIM01000042_gene1869	5.637e-56	202.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,375J4@32061|Chloroflexia	32061|Chloroflexia	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DTH3_k127_3985042_4	497964.CfE428DRAFT_2605	1.839e-21	96.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
DTH3_k127_3985042_1	401526.TcarDRAFT_0104	8.169e-102	357.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DTH3_k127_3985042_3	1335757.SPICUR_00600	1.68e-48	177.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,1WZSQ@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_4000628_1	1396141.BATP01000016_gene2780	4.858e-159	546.0	COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.5.4.40	ko:K18286,ko:K20276	ko00130,ko01110,ko02024,map00130,map01110,map02024	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_8,Big_5,SLH,SWM_repeat
DTH3_k127_4000628_3	1121403.AUCV01000017_gene4438	8.079e-85	297.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2MIPA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
DTH3_k127_4000628_8	1123070.KB899247_gene1454	1.426e-43	167.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Glycerol-3-phosphate acyltransferase	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
DTH3_k127_4000628_2	497964.CfE428DRAFT_0881	3.604e-107	359.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_4000628_7	481448.Minf_1859	1.618e-69	256.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,37GGI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
DTH3_k127_4000628_9	497964.CfE428DRAFT_6314	2.347e-24	111.0	2E63P@1|root,330SQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4000628_5	497964.CfE428DRAFT_5455	3.523e-71	246.0	COG2344@1|root,COG2344@2|Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
DTH3_k127_4000628_10	452637.Oter_1279	2.266e-12	74.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF285,Flg_new,HWE_HK,PAS_10,SBP_bac_5
DTH3_k127_4000628_0	452637.Oter_2454	7.036e-251	785.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
DTH3_k127_4000628_6	530564.Psta_0956	9.932e-70	247.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH3_k127_4000628_11	1123242.JH636434_gene4823	1.766e-07	56.0	COG2133@1|root,COG2133@2|Bacteria,2IWVG@203682|Planctomycetes	203682|Planctomycetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4000628_4	153948.NAL212_2951	1.486e-76	265.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,2VK8B@28216|Betaproteobacteria,373J4@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Transposase, IS4-like	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
DTH3_k127_4006985_1	382464.ABSI01000002_gene4315	8.191e-74	273.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46X8V@74201|Verrucomicrobia,2IV1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4006985_2	335543.Sfum_0973	3.299e-65	228.0	COG0110@1|root,COG0110@2|Bacteria,1PFB8@1224|Proteobacteria,439Z7@68525|delta/epsilon subdivisions,2X1Z1@28221|Deltaproteobacteria,2MSCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH3_k127_4006985_0	1396141.BATP01000036_gene3854	1.385e-91	308.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_4020767_0	478741.JAFS01000002_gene302	1.28e-154	505.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,37G1H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
DTH3_k127_4032469_2	411479.BACUNI_04071	1.476e-22	102.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_4032469_0	1121106.JQKB01000056_gene5861	0.0	1146.0	COG1413@1|root,COG1413@2|Bacteria,1R5Z1@1224|Proteobacteria	1224|Proteobacteria	C	lyase activity	capB	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	-
DTH3_k127_4034320_1	314230.DSM3645_10162	2.041e-87	298.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH3_k127_4034320_4	1396141.BATP01000045_gene1848	1.208e-08	68.0	COG2911@1|root,COG3866@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG3866@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH3_k127_4034320_0	391625.PPSIR1_08312	8.443e-130	437.0	COG5434@1|root,COG5434@2|Bacteria,1RJPM@1224|Proteobacteria,42T21@68525|delta/epsilon subdivisions,2WPCS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH3_k127_4034320_3	504728.K649_06595	2.1e-61	225.0	COG3257@1|root,COG3257@2|Bacteria,1WJWA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein possibly involved in glyoxylate utilization	-	-	3.5.3.26	ko:K14977	ko00230,ko01120,map00230,map01120	-	R05554	RC01419	ko00000,ko00001,ko01000	-	-	-	Cupin_2
DTH3_k127_4034320_2	765912.Thimo_3050	5.437e-85	286.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
DTH3_k127_4039525_0	1396141.BATP01000056_gene3278	1.151e-38	167.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
DTH3_k127_4039525_1	56780.SYN_01127	7.509e-33	148.0	COG1345@1|root,COG1957@1|root,COG3204@1|root,COG1345@2|Bacteria,COG1957@2|Bacteria,COG3204@2|Bacteria,1QVAA@1224|Proteobacteria,43BPG@68525|delta/epsilon subdivisions,2X70T@28221|Deltaproteobacteria,2MR3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4050758_0	411477.PARMER_03655	5.504e-68	244.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_4052714_0	661478.OP10G_1743	5.943e-190	608.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127,RicinB_lectin_2
DTH3_k127_4052714_1	497964.CfE428DRAFT_2508	2.109e-77	263.0	COG0066@1|root,COG0066@2|Bacteria,46TAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
DTH3_k127_4052714_2	292459.STH304	7.006e-47	178.0	COG3525@1|root,COG3525@2|Bacteria,1TSXM@1239|Firmicutes,248U1@186801|Clostridia	186801|Clostridia	G	hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
DTH3_k127_407962_0	1210884.HG799462_gene9284	3.092e-80	276.0	COG0584@1|root,COG0584@2|Bacteria,2IYVE@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD_2
DTH3_k127_407962_2	794903.OPIT5_09565	1.575e-07	62.0	COG4969@1|root,COG4969@2|Bacteria,46YC2@74201|Verrucomicrobia,3K9A9@414999|Opitutae	414999|Opitutae	NU	Belongs to the N-Me-Phe pilin family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_407962_1	886293.Sinac_3761	1.398e-13	74.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_4082677_0	639030.JHVA01000001_gene2781	7.545e-173	554.0	COG0673@1|root,COG0673@2|Bacteria,3Y6C9@57723|Acidobacteria,2JKU9@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_4082677_4	290397.Adeh_1033	7.634e-23	107.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH3_k127_4082677_1	225849.swp_0274	8.913e-81	283.0	2910Q@1|root,2ZNNC@2|Bacteria,1PCP3@1224|Proteobacteria,1S0BX@1236|Gammaproteobacteria,2Q953@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4082677_2	1713.JOFV01000006_gene2655	3.917e-50	185.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4F201@85016|Cellulomonadaceae	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DTH3_k127_4082677_3	479435.Kfla_6730	9.829e-31	131.0	2CPKI@1|root,32SJC@2|Bacteria,2IQPS@201174|Actinobacteria,4DS6U@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
DTH3_k127_4082677_5	1121405.dsmv_3117	2.655e-09	60.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2X6EH@28221|Deltaproteobacteria,2MN74@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH3_k127_4095451_0	497964.CfE428DRAFT_5035	2.758e-250	778.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DTH3_k127_4095451_1	307480.IW16_23585	6.229e-29	132.0	COG5184@1|root,COG5184@2|Bacteria,4NIP4@976|Bacteroidetes,1IIHQ@117743|Flavobacteriia,3ZNMC@59732|Chryseobacterium	976|Bacteroidetes	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,RCC1
DTH3_k127_4106623_3	497964.CfE428DRAFT_4533	1.974e-89	298.0	COG1657@1|root,COG1657@2|Bacteria,46TYK@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH3_k127_4106623_0	497964.CfE428DRAFT_4532	2.32e-159	516.0	COG0737@1|root,COG0737@2|Bacteria,46TFI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
DTH3_k127_4106623_4	794903.OPIT5_25305	2.129e-27	121.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
DTH3_k127_4106623_2	886293.Sinac_2458	2.521e-132	432.0	COG0399@1|root,COG0399@2|Bacteria,2IXZR@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH3_k127_4106623_5	243230.DR_0026	5.101e-09	67.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
DTH3_k127_4106623_1	1236959.BAMT01000001_gene1712	1.826e-154	513.0	COG0515@1|root,COG0515@2|Bacteria,1R6F6@1224|Proteobacteria,2W1UW@28216|Betaproteobacteria,2KKN2@206350|Nitrosomonadales	206350|Nitrosomonadales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
DTH3_k127_4106623_6	658086.HMPREF0994_00109	0.0003206	49.0	2EGCD@1|root,33A46@2|Bacteria,1VMG3@1239|Firmicutes,24UKI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4110152_4	1173263.Syn7502_01724	1.218e-10	66.0	COG4634@1|root,COG4634@2|Bacteria,1GA41@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4110152_2	575540.Isop_1515	4.296e-45	176.0	COG1975@1|root,COG1975@2|Bacteria,2IXRN@203682|Planctomycetes	203682|Planctomycetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
DTH3_k127_4110152_1	292563.Cyast_2134	1.998e-59	214.0	COG0642@1|root,COG2205@2|Bacteria,1G3D2@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
DTH3_k127_4110152_0	1396141.BATP01000004_gene5820	2.925e-60	217.0	COG0551@1|root,COG0551@2|Bacteria,46SJD@74201|Verrucomicrobia,2IVAK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
DTH3_k127_4119387_1	869213.JCM21142_83218	0.0001182	54.0	COG1621@1|root,COG1621@2|Bacteria,4NG4M@976|Bacteroidetes,47TNW@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
DTH3_k127_4119387_0	1123276.KB893246_gene561	3.811e-15	90.0	COG2010@1|root,COG3345@1|root,COG4625@1|root,COG2010@2|Bacteria,COG3345@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
DTH3_k127_4120725_3	269799.Gmet_2562	1.041e-30	136.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
DTH3_k127_4120725_0	880072.Desac_0330	2.947e-113	384.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_4120725_1	497964.CfE428DRAFT_2670	8.939e-66	234.0	COG1562@1|root,COG1562@2|Bacteria,46TVP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Amino_oxidase,SQS_PSY
DTH3_k127_4120725_4	596328.HMPREF0578_1655	4.647e-05	53.0	COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4D3DV@85005|Actinomycetales	201174|Actinobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DTH3_k127_4120725_2	1191523.MROS_1767	4.132e-51	187.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
DTH3_k127_4126300_2	452637.Oter_2116	4.421e-78	273.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4126300_5	525146.Ddes_0534	2.336e-06	59.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,2MC24@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH3_k127_4126300_1	644282.Deba_0203	6.165e-84	286.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH3_k127_4126300_3	1396141.BATP01000007_gene5566	1.008e-69	246.0	COG0767@1|root,COG0767@2|Bacteria,46SXR@74201|Verrucomicrobia,2ITY5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
DTH3_k127_4126300_0	886293.Sinac_4596	4.633e-188	606.0	2DBS0@1|root,2ZANT@2|Bacteria,2IY4P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4126300_4	1366050.N234_35010	5.217e-31	127.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2VXQA@28216|Betaproteobacteria,1K3YT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4165852_0	926550.CLDAP_04870	1.476e-121	413.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DTH3_k127_4165852_2	1123242.JH636434_gene3261	0.0006341	44.0	2E02K@1|root,32KJE@2|Bacteria,2J430@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4165852_1	926550.CLDAP_03360	1.459e-26	119.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G6F0@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
DTH3_k127_4186890_2	1089550.ATTH01000001_gene181	7.483e-31	130.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1FJDT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
DTH3_k127_4186890_3	316274.Haur_4882	4.547e-12	78.0	2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi,375HC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LIM, zinc-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DA1-like
DTH3_k127_4186890_0	330214.NIDE2536	2.57e-216	687.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
DTH3_k127_4186890_1	497964.CfE428DRAFT_0818	4.171e-49	179.0	COG0046@1|root,COG0046@2|Bacteria,46S8Y@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
DTH3_k127_4196340_3	1298867.AUES01000063_gene24	2.298e-52	190.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DTH3_k127_4196340_4	1267533.KB906737_gene1998	2.377e-50	187.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4196340_1	1267534.KB906760_gene1239	1.071e-142	466.0	COG4325@1|root,COG4325@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
DTH3_k127_4196340_5	1397527.Q670_02705	6.464e-24	113.0	COG3637@1|root,COG3637@2|Bacteria,1NE9Q@1224|Proteobacteria,1T3ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4196340_0	452637.Oter_0554	2.062e-191	608.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
DTH3_k127_4196340_2	1396141.BATP01000042_gene1909	6.147e-105	352.0	COG3829@1|root,COG3829@2|Bacteria,46UZT@74201|Verrucomicrobia,2IVHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
DTH3_k127_4197031_0	1303518.CCALI_02490	7.091e-82	282.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_4197031_1	419610.Mext_3251	2.458e-19	101.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,2U187@28211|Alphaproteobacteria,1JT6I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_4197031_2	555779.Dthio_PD0141	6.584e-08	62.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,1MU5I@1224|Proteobacteria	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_4197395_7	1226325.HMPREF1548_00033	2.301e-05	49.0	COG3170@1|root,COG3170@2|Bacteria,1US63@1239|Firmicutes,24YI9@186801|Clostridia	186801|Clostridia	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4197395_5	547042.BACCOPRO_02222	1.884e-07	64.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxidN1,DUF3370,DUF4985,GHL10,Melibiase,Metallophos,MetallophosC,MetallophosN,SLH,WG_beta_rep
DTH3_k127_4197395_0	886293.Sinac_3681	4.285e-119	411.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	bgaB	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
DTH3_k127_4197395_1	1396141.BATP01000047_gene3930	7.865e-65	227.0	COG3476@1|root,COG3476@2|Bacteria,46SXT@74201|Verrucomicrobia,2IVZD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	TspO/MBR family	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
DTH3_k127_4197395_2	472759.Nhal_2122	1.952e-37	148.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria,1T2N4@1236|Gammaproteobacteria,1WYK0@135613|Chromatiales	135613|Chromatiales	GM	intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
DTH3_k127_4197395_8	196367.JNFG01000216_gene660	5.108e-05	51.0	COG0702@1|root,COG0702@2|Bacteria,1MZ0C@1224|Proteobacteria,2VNMR@28216|Betaproteobacteria,1K4VX@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3,Epimerase,NAD_binding_10
DTH3_k127_4197395_9	797303.Natpe_3981	0.0003006	46.0	COG2002@1|root,arCOG00812@2157|Archaea,2Y4G4@28890|Euryarchaeota,2404J@183963|Halobacteria	183963|Halobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
DTH3_k127_4197395_4	743836.AYNA01000111_gene20	8.663e-10	64.0	COG1487@1|root,COG1487@2|Bacteria,1RJ2J@1224|Proteobacteria,2UA97@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
DTH3_k127_4197395_3	1160718.SU9_03606	2.953e-11	72.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2GKEU@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
DTH3_k127_4197395_6	63737.Npun_F5091	3.296e-06	50.0	COG2944@1|root,COG2944@2|Bacteria,1GB8Y@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
DTH3_k127_4205758_1	1205680.CAKO01000002_gene2680	3.412e-10	61.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497,ko:K09958	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,Mu-transpos_C,rve,rve_3
DTH3_k127_4205758_0	653733.Selin_0475	3.618e-144	465.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
DTH3_k127_4207667_3	1408254.T458_02935	5.768e-21	104.0	COG4244@1|root,COG4244@2|Bacteria,1UHFB@1239|Firmicutes,4HCQT@91061|Bacilli,26UEU@186822|Paenibacillaceae	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4207667_1	452637.Oter_3700	1.69e-101	339.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH3_k127_4207667_2	1115632.JAFW01000001_gene36	4.326e-42	165.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,1W83K@1268|Micrococcaceae	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
DTH3_k127_4207667_0	1210884.HG799462_gene8336	3.715e-111	375.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_4208069_0	1174528.JH992898_gene4971	2.171e-254	798.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria,1JGWD@1189|Stigonemataceae	1117|Cyanobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
DTH3_k127_4218150_3	886293.Sinac_0924	7.301e-22	96.0	COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
DTH3_k127_4218150_0	886293.Sinac_3461	4.02e-224	707.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH3_k127_4218150_2	1313301.AUGC01000009_gene1068	2.968e-58	212.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes	976|Bacteroidetes	T	protein tyrosine phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
DTH3_k127_4218150_1	1210884.HG799462_gene8241	6.359e-102	345.0	COG1520@1|root,COG1520@2|Bacteria,2J1S1@203682|Planctomycetes	203682|Planctomycetes	P	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_4232863_2	1229780.BN381_350147	2.063e-07	63.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3
DTH3_k127_4232863_3	58123.JOFJ01000024_gene3453	0.0003818	53.0	COG1277@1|root,COG1277@2|Bacteria,2IIXQ@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
DTH3_k127_4232863_0	575540.Isop_1673	7.97e-88	301.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_4232863_1	521674.Plim_0255	4.305e-08	66.0	2DN3F@1|root,32VAJ@2|Bacteria,2IZBX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4250227_4	1269813.ATUL01000021_gene759	3.876e-27	127.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor arsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
DTH3_k127_4250227_1	556269.ACDQ01000009_gene1948	2.403e-95	331.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
DTH3_k127_4250227_10	1280953.HOC_18234	6.001e-07	55.0	2EPBI@1|root,33GYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4250227_2	1396141.BATP01000003_gene5267	5.248e-71	244.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
DTH3_k127_4250227_3	278957.ABEA03000004_gene4516	1.741e-34	138.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
DTH3_k127_4250227_7	1408428.JNJP01000055_gene143	1.21e-18	91.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria,2MC9Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DTH3_k127_4250227_9	521674.Plim_0147	7.594e-08	61.0	2DMHQ@1|root,32RMG@2|Bacteria,2J02C@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
DTH3_k127_4250227_6	1304885.AUEY01000001_gene3204	5.788e-20	101.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4250227_5	402880.MmarC5_0718	3.513e-21	102.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23QEP@183939|Methanococci	183939|Methanococci	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH3_k127_4250227_0	909663.KI867150_gene1425	9.859e-100	329.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DTH3_k127_4261061_1	402777.KB235903_gene711	9.723e-60	213.0	COG0500@1|root,COG0500@2|Bacteria,1GHCT@1117|Cyanobacteria,1HHS8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
DTH3_k127_4261061_3	1396141.BATP01000059_gene2442	1.962e-17	88.0	COG5620@1|root,COG5620@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
DTH3_k127_4261061_2	1396141.BATP01000059_gene2441	5.627e-49	179.0	COG5620@1|root,COG5620@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
DTH3_k127_4261061_4	314230.DSM3645_12146	6.782e-10	63.0	COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH3_k127_4261061_0	880072.Desac_1923	1.498e-147	469.0	COG2519@1|root,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,42NCI@68525|delta/epsilon subdivisions,2WJUH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH3_k127_4314998_0	382464.ABSI01000009_gene3917	5.631e-131	426.0	COG1131@1|root,COG1131@2|Bacteria,46SHV@74201|Verrucomicrobia,2ITWN@203494|Verrucomicrobiae	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_4314998_1	382464.ABSI01000009_gene3916	1.37e-35	147.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
DTH3_k127_4320523_0	497964.CfE428DRAFT_6477	5.415e-21	108.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46UDW@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH3_k127_4332935_1	192952.MM_1779	6.856e-74	254.0	COG1926@1|root,arCOG06847@2157|Archaea,2XWRW@28890|Euryarchaeota,2NABG@224756|Methanomicrobia	224756|Methanomicrobia	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
DTH3_k127_4332935_0	497964.CfE428DRAFT_3666	4.147e-92	311.0	COG1409@1|root,COG1409@2|Bacteria,46TUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH3_k127_4335876_0	497964.CfE428DRAFT_3502	2.667e-250	791.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46THN@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_4335876_1	697281.Mahau_1958	2.413e-65	234.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,42HRH@68295|Thermoanaerobacterales	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
DTH3_k127_4337727_1	1267533.KB906738_gene2187	2.368e-42	158.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DTH3_k127_4337727_0	1267533.KB906738_gene2186	5.394e-290	906.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
DTH3_k127_4337727_2	313603.FB2170_00745	4.429e-21	102.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I0C1@117743|Flavobacteriia,2PIGK@252356|Maribacter	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	tolB3	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH3_k127_4344871_1	290397.Adeh_2684	2.745e-41	159.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
DTH3_k127_4344871_3	404380.Gbem_1922	1.448e-23	119.0	COG1361@1|root,COG3055@1|root,COG3420@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
DTH3_k127_4344871_2	251221.35213566	8.598e-30	139.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4344871_0	382464.ABSI01000013_gene1839	1.727e-97	358.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
DTH3_k127_4345001_0	452637.Oter_0887	3.543e-50	199.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4345001_1	497964.CfE428DRAFT_5674	6.588e-50	186.0	COG0586@1|root,COG0586@2|Bacteria,46SWW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
DTH3_k127_4345001_2	497964.CfE428DRAFT_0418	1.444e-23	101.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DTH3_k127_436318_0	1444712.BN1013_00207	1.522e-108	358.0	COG0343@1|root,COG0343@2|Bacteria,2JFX0@204428|Chlamydiae	204428|Chlamydiae	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DTH3_k127_436318_1	1288963.ADIS_2824	6.048e-51	192.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,47JU7@768503|Cytophagia	976|Bacteroidetes	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DTH3_k127_4384239_2	452637.Oter_0327	3.888e-06	61.0	COG3507@1|root,COG3507@2|Bacteria,46TKI@74201|Verrucomicrobia,3KA3C@414999|Opitutae	2|Bacteria	G	PFAM glycoside hydrolase family 62	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_4_9,CBM_6,DUF1080,DUF1349,DUF5011,Flg_new,GSDH,Glyco_hydro_43,Laminin_G_3,PKD,RicinB_lectin_2,SLH,ThuA
DTH3_k127_4384239_1	153721.MYP_3853	2.093e-33	150.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH3_k127_4384239_0	583355.Caka_1736	1.583e-160	539.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_4384919_4	1403819.BATR01000027_gene886	5.733e-10	59.0	COG3345@1|root,COG3345@2|Bacteria,46XA8@74201|Verrucomicrobia,2IV69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
DTH3_k127_4384919_1	497964.CfE428DRAFT_1769	5.267e-263	819.0	28MCY@1|root,2ZAQW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4384919_0	497964.CfE428DRAFT_0038	1.602e-282	882.0	28MCY@1|root,2ZAQW@2|Bacteria,46TDW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4384919_2	1403819.BATR01000027_gene886	1.193e-189	599.0	COG3345@1|root,COG3345@2|Bacteria,46XA8@74201|Verrucomicrobia,2IV69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
DTH3_k127_4384919_3	661478.OP10G_4327	6.672e-154	498.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,DUF4038,DUF5060,F5_F8_type_C,Glyco_hydro_81
DTH3_k127_4385534_0	1403819.BATR01000125_gene4494	4.95e-173	579.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH3_k127_4385534_1	485918.Cpin_3102	5.583e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_4385534_2	278957.ABEA03000004_gene4535	1.758e-22	109.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH3_k127_4392334_2	1122927.KB895428_gene299	3.2e-06	51.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H9KJ@91061|Bacilli,26STY@186822|Paenibacillaceae	91061|Bacilli	G	sugar phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_4392334_1	1280947.HY30_08240	7.863e-11	73.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2TR27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_19820	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH3_k127_4392334_0	497964.CfE428DRAFT_5399	3.512e-50	190.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
DTH3_k127_4402522_1	794903.OPIT5_01655	8.994e-115	381.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia,3KA2J@414999|Opitutae	414999|Opitutae	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DTH3_k127_4402522_0	583355.Caka_0776	5.041e-143	460.0	COG0714@1|root,COG0714@2|Bacteria,46SC8@74201|Verrucomicrobia,3K7W0@414999|Opitutae	414999|Opitutae	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH3_k127_4402522_3	240015.ACP_0051	7.958e-15	78.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
DTH3_k127_4402522_2	1167006.UWK_00745	1.661e-71	250.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2MJBE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH3_k127_4414373_1	452637.Oter_1389	8.657e-122	397.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH3_k127_4414373_3	452637.Oter_2422	1.633e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_4414373_0	1122605.KB893643_gene530	2.282e-218	699.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
DTH3_k127_4414373_2	1396141.BATP01000006_gene5485	3.054e-101	355.0	COG0213@1|root,COG0213@2|Bacteria,46X9Z@74201|Verrucomicrobia,2IV5J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
DTH3_k127_4414373_4	1101190.ARWB01000001_gene2868	2.698e-42	162.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSX8@28211|Alphaproteobacteria,36ZCT@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Iron-containing alcohol dehydrogenase	mdh1	-	1.1.1.1,1.1.1.61	ko:K00001,ko:K00043	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
DTH3_k127_4417439_0	321332.CYB_2140	5.344e-18	98.0	COG2373@1|root,COG2373@2|Bacteria,1G1A1@1117|Cyanobacteria,1H0M9@1129|Synechococcus	1117|Cyanobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,CarboxypepD_reg,MG1,Thiol-ester_cl
DTH3_k127_4436981_2	742725.HMPREF9450_01532	6.202e-25	110.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,2FQGR@200643|Bacteroidia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH3_k127_4436981_3	864051.BurJ1DRAFT_0942	1.068e-13	82.0	COG1520@1|root,COG1520@2|Bacteria,1P0W9@1224|Proteobacteria	1224|Proteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4436981_4	1303518.CCALI_01450	3.888e-11	74.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_4436981_0	1165841.SULAR_01175	6.669e-42	162.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
DTH3_k127_4436981_1	269798.CHU_0700	9.921e-35	138.0	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,47XSN@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
DTH3_k127_4454294_0	292459.STH2173	1.038e-142	488.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DTH3_k127_4454294_1	1121428.DESHY_110314___1	1.064e-124	436.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,260SC@186807|Peptococcaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
DTH3_k127_4459758_1	1142394.PSMK_06110	5.808e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_4459758_0	583355.Caka_0956	9.748e-95	327.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
DTH3_k127_4459758_2	1090319.KE386571_gene1010	0.0005621	42.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,2U55E@28211|Alphaproteobacteria,2K0AF@204457|Sphingomonadales	204457|Sphingomonadales	G	Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
DTH3_k127_448466_0	1267535.KB906767_gene3736	2.586e-247	773.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH3_k127_4491769_7	1123008.KB905695_gene2653	1.128e-05	60.0	COG3345@1|root,COG4733@1|root,COG3345@2|Bacteria,COG4733@2|Bacteria,4NHM7@976|Bacteroidetes,2FNUE@200643|Bacteroidia,22WN2@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	CBM_35
DTH3_k127_4491769_4	765420.OSCT_3130	4.352e-47	197.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
DTH3_k127_4491769_6	1123277.KB893172_gene995	2.126e-32	149.0	COG1520@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K02406,ko:K21449	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02000,ko02035	1.B.40.2	-	-	Beta_helix,DUF5122
DTH3_k127_4491769_2	1499967.BAYZ01000068_gene1935	1.087e-69	272.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
DTH3_k127_4491769_0	1123242.JH636434_gene3161	2.276e-151	487.0	COG1915@1|root,COG1915@2|Bacteria,2IXX9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4491769_1	497964.CfE428DRAFT_1935	9.381e-130	422.0	COG2870@1|root,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,Hydrolase,PfkB
DTH3_k127_4491769_3	1304275.C41B8_01647	7.273e-65	229.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
DTH3_k127_4491769_5	243233.MCA2756	1.322e-40	153.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
DTH3_k127_4509492_11	401526.TcarDRAFT_0315	1.622e-23	106.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4H2KA@909932|Negativicutes	909932|Negativicutes	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
DTH3_k127_4509492_5	1156937.MFUM_1020111	2.205e-118	396.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,37FVJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
DTH3_k127_4509492_12	96561.Dole_1196	8.771e-05	53.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
DTH3_k127_4509492_3	497964.CfE428DRAFT_0922	3.033e-129	422.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH3_k127_4509492_7	497964.CfE428DRAFT_3169	2.359e-91	317.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
DTH3_k127_4509492_10	756272.Plabr_2390	1.001e-51	194.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
DTH3_k127_4509492_9	1121440.AUMA01000005_gene2574	2.254e-80	289.0	COG0546@1|root,COG3173@1|root,COG0546@2|Bacteria,COG3173@2|Bacteria,1R5MY@1224|Proteobacteria,435UQ@68525|delta/epsilon subdivisions,2X9D0@28221|Deltaproteobacteria,2MBGQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
DTH3_k127_4509492_4	1121033.AUCF01000009_gene1173	1.077e-121	397.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,2JSWY@204441|Rhodospirillales	204441|Rhodospirillales	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH3_k127_4509492_2	1121033.AUCF01000009_gene1174	1.155e-132	428.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,2JSGM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG3959 Transketolase, N-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DTH3_k127_4509492_6	614083.AWQR01000023_gene151	1.051e-102	344.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH3_k127_4509492_0	402777.KB235904_gene3439	2.236e-134	444.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1G2IU@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM rfaE bifunctional protein, domain I	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
DTH3_k127_4509492_8	1121440.AUMA01000005_gene2575	4.454e-81	282.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2WQ8F@28221|Deltaproteobacteria,2MB41@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH3_k127_4509492_1	652103.Rpdx1_1424	7.891e-134	434.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,3JRQ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46,4.2.1.76,5.1.3.2	ko:K01710,ko:K01784,ko:K12450	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00293,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DTH3_k127_4515668_2	886379.AEWI01000012_gene1029	1.438e-82	286.0	COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,2FQW5@200643|Bacteroidia	976|Bacteroidetes	G	Domain of unknown function	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001
DTH3_k127_4515668_3	96561.Dole_0975	1.432e-58	208.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MPU9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH3_k127_4515668_5	1121456.ATVA01000014_gene561	1.015e-40	160.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MAUU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH3_k127_4515668_7	530564.Psta_1718	8.456e-23	101.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DTH3_k127_4515668_4	497964.CfE428DRAFT_6239	4.062e-53	188.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
DTH3_k127_4515668_0	794903.OPIT5_00465	1.469e-142	467.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,3K7HJ@414999|Opitutae	414999|Opitutae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DTH3_k127_4515668_1	497964.CfE428DRAFT_0801	3.64e-121	398.0	COG4586@1|root,COG4586@2|Bacteria,46TXF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_4515668_6	382464.ABSI01000009_gene3989	4.018e-40	160.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4
DTH3_k127_4517587_3	1403819.BATR01000031_gene981	5.968e-106	359.0	COG1793@1|root,COG1793@2|Bacteria,46TK9@74201|Verrucomicrobia,2IV60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_4517587_0	497964.CfE428DRAFT_0415	3.809e-175	560.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
DTH3_k127_4517587_7	1123252.ATZF01000020_gene2901	3.607e-25	112.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,27C4B@186824|Thermoactinomycetaceae	91061|Bacilli	H	5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
DTH3_k127_4517587_2	1382304.JNIL01000001_gene534	4.558e-139	458.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,277VR@186823|Alicyclobacillaceae	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DTH3_k127_4517587_10	478741.JAFS01000002_gene111	1.018e-06	59.0	COG1196@1|root,COG1196@2|Bacteria,46Z83@74201|Verrucomicrobia,37GKF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4517587_8	391587.KAOT1_16038	4.751e-25	115.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH3_k127_4517587_5	309807.SRU_2566	6.247e-35	152.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1FJBA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
DTH3_k127_4517587_6	717605.Theco_1040	1.484e-28	124.0	COG0128@1|root,COG0128@2|Bacteria,1VK19@1239|Firmicutes,4HQZ9@91061|Bacilli,26WZM@186822|Paenibacillaceae	91061|Bacilli	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4517587_4	497964.CfE428DRAFT_1897	6.41e-88	303.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
DTH3_k127_4517587_1	497964.CfE428DRAFT_0339	1.052e-148	484.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
DTH3_k127_4526327_1	497964.CfE428DRAFT_2907	1.659e-89	302.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DTH3_k127_4526327_0	497964.CfE428DRAFT_6681	5.251e-184	587.0	COG0535@1|root,COG0535@2|Bacteria,46V38@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
DTH3_k127_4530069_3	324602.Caur_2210	4.996e-35	139.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
DTH3_k127_4530069_1	1123070.KB899255_gene1382	6.138e-122	412.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,2ITRD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DHHA1 domain	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH3_k127_4530069_2	579405.Dd703_0239	4.274e-77	267.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,2JCM1@204037|Dickeya	1236|Gammaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
DTH3_k127_4530069_0	583355.Caka_0705	4.64e-168	536.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_4531236_1	555079.Toce_0657	2.379e-116	387.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
DTH3_k127_4531236_2	1267535.KB906767_gene1026	3.834e-71	260.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_4531236_0	1288963.ADIS_4374	3.396e-225	722.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4543874_0	118168.MC7420_2493	3.502e-79	283.0	COG1404@1|root,COG2931@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
DTH3_k127_4543874_1	344747.PM8797T_30449	4.356e-10	64.0	294P7@1|root,2ZS2I@2|Bacteria,2J4KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_454904_0	861299.J421_1753	1.855e-287	922.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH3_k127_454904_1	1123242.JH636434_gene4592	2.681e-16	92.0	COG3712@1|root,COG3712@2|Bacteria,2IZ99@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,Laminin_G_3
DTH3_k127_454904_2	1121373.KB903632_gene508	1.756e-08	67.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
DTH3_k127_4549455_0	1235803.C825_03594	4.19e-165	537.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH3_k127_4549455_1	1288963.ADIS_4732	2.925e-120	392.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_4554117_0	497964.CfE428DRAFT_1708	1.279e-168	539.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
DTH3_k127_4554117_1	903818.KI912268_gene822	6.92e-40	152.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
DTH3_k127_4562272_0	401053.AciPR4_2231	1.135e-125	437.0	COG3250@1|root,COG3250@2|Bacteria,3Y62S@57723|Acidobacteria,2JM9E@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_4562272_1	1550091.JROE01000008_gene3578	0.0004865	51.0	2DBF9@1|root,2Z8X9@2|Bacteria,4NHC2@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109
DTH3_k127_4563334_0	1396141.BATP01000056_gene3278	1.307e-44	186.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
DTH3_k127_4563334_1	856793.MICA_1644	1.146e-11	79.0	COG1520@1|root,COG3533@1|root,COG1520@2|Bacteria,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,DUF4832,Laminin_G_3,PQQ_2,PQQ_3
DTH3_k127_4570777_3	794903.OPIT5_27515	8.514e-22	98.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
DTH3_k127_4570777_0	1123508.JH636441_gene3126	2.013e-231	736.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH3_k127_4570777_1	497964.CfE428DRAFT_6276	7.651e-72	268.0	COG2755@1|root,COG2755@2|Bacteria,46SVE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_4570777_2	278963.ATWD01000001_gene2920	3.106e-38	146.0	2CK7V@1|root,2Z9WF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4582293_0	935845.JADQ01000029_gene1230	6.432e-94	344.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
DTH3_k127_4606197_11	1121373.KB903654_gene1652	5.125e-05	57.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	ydcK	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CBM_35,NTP_transf_3,PEP_mutase
DTH3_k127_4606197_6	869213.JCM21142_72843	3.442e-24	120.0	COG1404@1|root,COG3210@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125,ko:K21449	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536,ko02000	1.B.40.2	-	-	5_nucleotid_C,CW_binding_2,Fil_haemagg,Haemagg_act,He_PIG,HemolysinCabind,LTD,Metallophos,PATR
DTH3_k127_4606197_3	1123399.AQVE01000001_gene684	1.666e-109	390.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
DTH3_k127_4606197_7	794903.OPIT5_08660	2.039e-16	89.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_4606197_9	378806.STAUR_0706	1.051e-09	70.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X7B6@28221|Deltaproteobacteria,2YUAZ@29|Myxococcales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
DTH3_k127_4606197_10	706587.Desti_1174	1.581e-06	60.0	COG2204@1|root,COG2204@2|Bacteria,1RKC4@1224|Proteobacteria,42SJ3@68525|delta/epsilon subdivisions,2WPI1@28221|Deltaproteobacteria,2MRU7@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DTH3_k127_4606197_8	335543.Sfum_0069	6.835e-14	84.0	COG1357@1|root,COG2201@1|root,COG1357@2|Bacteria,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K18876	ko02020,ko02030,ko04626,map02020,map02030,map04626	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,DDE_5,Response_reg,TAL_effector
DTH3_k127_4606197_0	240016.ABIZ01000001_gene5946	5.868e-175	561.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia,2IWJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_4606197_4	497964.CfE428DRAFT_0981	3.417e-106	354.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
DTH3_k127_4606197_2	521674.Plim_1708	7.091e-114	381.0	COG1793@1|root,COG1793@2|Bacteria,2J0I2@203682|Planctomycetes	203682|Planctomycetes	L	secreted glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_4606197_1	1396141.BATP01000029_gene2231	9.435e-159	541.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH3_k127_4606197_5	485918.Cpin_3102	2.109e-60	215.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_4624525_0	1123242.JH636435_gene2166	9.616e-34	143.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
DTH3_k127_4624525_1	1123508.JH636450_gene7091	6.833e-07	60.0	COG4795@1|root,COG4795@2|Bacteria,2J03I@203682|Planctomycetes	203682|Planctomycetes	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH3_k127_4624525_2	1479238.JQMZ01000001_gene267	0.0003691	48.0	COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria,2UK2Q@28211|Alphaproteobacteria,43YW6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NU	General secretion pathway protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
DTH3_k127_4647293_4	1321781.HMPREF1985_01034	3.158e-66	234.0	COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4H38R@909932|Negativicutes	909932|Negativicutes	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_4647293_2	521045.Kole_0981	1.902e-79	277.0	COG0524@1|root,COG0524@2|Bacteria,2GDS1@200918|Thermotogae	200918|Thermotogae	H	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DTH3_k127_4647293_3	861299.J421_0058	5.964e-67	238.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH3_k127_4647293_0	1122947.FR7_2048	6.301e-107	363.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4H6Y8@909932|Negativicutes	909932|Negativicutes	EH	Anthranilate synthase component I, N terminal region	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH3_k127_4647293_5	247490.KSU1_C0572	3.963e-45	175.0	COG0115@1|root,COG0115@2|Bacteria,2J20K@203682|Planctomycetes	203682|Planctomycetes	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
DTH3_k127_4647293_6	935948.KE386495_gene2110	3.531e-35	144.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GS3@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DTH3_k127_4647293_7	382464.ABSI01000010_gene3682	1.82e-18	97.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DTH3_k127_4647293_1	1541065.JRFE01000011_gene4569	6.058e-88	312.0	COG1305@1|root,COG1305@2|Bacteria,1G1YY@1117|Cyanobacteria,3VKRN@52604|Pleurocapsales	1117|Cyanobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH3_k127_4648619_1	886293.Sinac_0185	7.012e-37	161.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
DTH3_k127_4648619_0	1210884.HG799476_gene15380	1.597e-58	229.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
DTH3_k127_4686700_0	1278073.MYSTI_03564	1.009e-225	742.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DTH3_k127_4686700_1	929562.Emtol_2733	1.728e-21	108.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,47X99@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH3_k127_4695915_1	1449049.JONW01000013_gene4657	2.444e-91	317.0	COG5164@1|root,COG5164@2|Bacteria,1MX1Z@1224|Proteobacteria,2TWHE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4695915_0	497964.CfE428DRAFT_1137	7.882e-261	811.0	COG0282@1|root,COG4869@1|root,COG0282@2|Bacteria,COG4869@2|Bacteria,46SKB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC,cNMP_binding
DTH3_k127_4701450_2	886293.Sinac_2505	1.56e-27	118.0	2ESSA@1|root,33KAQ@2|Bacteria,2J1KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4701450_1	234267.Acid_6639	7.441e-53	198.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
DTH3_k127_4701450_3	452637.Oter_1052	2.635e-12	73.0	COG0330@1|root,COG0330@2|Bacteria,46VZD@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH3_k127_4701450_4	640512.BC1003_5144	4.084e-07	53.0	COG1064@1|root,COG1064@2|Bacteria,1P0UC@1224|Proteobacteria,2VPCZ@28216|Betaproteobacteria,1KGVQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH3_k127_4701450_0	1242864.D187_008109	2.396e-122	402.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42PV7@68525|delta/epsilon subdivisions,2WKXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
DTH3_k127_4710464_13	344747.PM8797T_04085	5.963e-05	48.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2IYF2@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
DTH3_k127_4710464_8	1123508.JH636439_gene990	2.819e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_4710464_1	1226994.AMZB01000119_gene3308	2.701e-114	396.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria,1YD63@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_4710464_5	247633.GP2143_17741	4.827e-73	254.0	COG4221@1|root,COG4221@2|Bacteria,1QXEV@1224|Proteobacteria,1T3J0@1236|Gammaproteobacteria,1JA36@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH3_k127_4710464_10	368407.Memar_0224	2.186e-07	59.0	COG2768@1|root,arCOG02448@2157|Archaea,2XW30@28890|Euryarchaeota,2N9AE@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
DTH3_k127_4710464_4	1125863.JAFN01000001_gene1137	1.715e-74	259.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42TJM@68525|delta/epsilon subdivisions,2WQGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DTH3_k127_4710464_9	497964.CfE428DRAFT_1105	6.564e-43	173.0	COG1427@1|root,COG1427@2|Bacteria,46VTU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DTH3_k127_4710464_7	478741.JAFS01000001_gene1574	1.69e-55	205.0	COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia,37G0D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH3_k127_4710464_11	497964.CfE428DRAFT_3787	2.469e-06	60.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4710464_3	1340493.JNIF01000003_gene3916	1.596e-85	301.0	COG2006@1|root,COG2006@2|Bacteria,3Y6M1@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH3_k127_4710464_2	497964.CfE428DRAFT_0699	1.202e-85	301.0	COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,46UKB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DTH3_k127_4710464_0	1403819.BATR01000153_gene5138	1.605e-136	449.0	COG4948@1|root,COG4948@2|Bacteria,46S7G@74201|Verrucomicrobia,2IV9V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4710464_6	1340493.JNIF01000003_gene1832	9.569e-69	235.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
DTH3_k127_4713645_1	497964.CfE428DRAFT_5081	1.784e-31	127.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_4713645_0	1396141.BATP01000003_gene5036	7.808e-271	880.0	COG2931@1|root,COG3299@1|root,COG4733@1|root,COG5267@1|root,COG2931@2|Bacteria,COG3299@2|Bacteria,COG4733@2|Bacteria,COG5267@2|Bacteria,46TXW@74201|Verrucomicrobia,2IWPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH3_k127_4722837_3	1396141.BATP01000003_gene5182	2.743e-22	99.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
DTH3_k127_4722837_2	344747.PM8797T_03609	3.833e-53	197.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
DTH3_k127_4722837_4	1095743.HMPREF1054_0309	2.833e-21	101.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y8T2@135625|Pasteurellales	135625|Pasteurellales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
DTH3_k127_4722837_0	452637.Oter_2821	1.622e-173	572.0	COG0755@1|root,COG0755@2|Bacteria,46SIH@74201|Verrucomicrobia,3K7UF@414999|Opitutae	414999|Opitutae	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DTH3_k127_4722837_1	452637.Oter_2587	3.159e-101	342.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
DTH3_k127_4722837_5	497964.CfE428DRAFT_1210	0.0001561	44.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4726005_0	452637.Oter_0693	1.76e-140	452.0	COG0019@1|root,COG0019@2|Bacteria,46WJD@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DTH3_k127_4726005_1	794903.OPIT5_23905	2.235e-09	67.0	COG2165@1|root,COG2165@2|Bacteria,46Z9G@74201|Verrucomicrobia,3K9NR@414999|Opitutae	2|Bacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_4732455_1	794903.OPIT5_23755	1.15e-121	396.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
DTH3_k127_4732455_2	497964.CfE428DRAFT_5447	1.367e-111	372.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
DTH3_k127_4732455_0	497964.CfE428DRAFT_6713	9.54e-235	737.0	COG3961@1|root,COG3961@2|Bacteria,46UYW@74201|Verrucomicrobia	74201|Verrucomicrobia	GH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH3_k127_4733407_1	1267535.KB906767_gene4363	1.686e-38	152.0	COG0383@1|root,COG0383@2|Bacteria,3Y77D@57723|Acidobacteria,2JKQ2@204432|Acidobacteriia	204432|Acidobacteriia	G	Polysaccharide lyase family 4, domain III	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_4733407_0	251221.35214444	5.595e-212	681.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
DTH3_k127_4739569_2	296587.XP_002507930.1	1.41e-16	83.0	2E1M9@1|root,2S8XU@2759|Eukaryota,37ZTR@33090|Viridiplantae,34KP7@3041|Chlorophyta	3041|Chlorophyta	S	Helicase associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HA
DTH3_k127_4739569_1	452637.Oter_1864	1.276e-19	103.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
DTH3_k127_4739569_4	1123035.ARLA01000026_gene170	0.0004358	51.0	COG0793@1|root,COG0793@2|Bacteria,4NIGU@976|Bacteroidetes,1I43H@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
DTH3_k127_4739569_0	1122165.AUHS01000032_gene2254	2.436e-23	113.0	2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,1STBF@1236|Gammaproteobacteria,1JD5H@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4739569_3	589865.DaAHT2_0221	7.658e-10	61.0	COG2172@1|root,COG2208@1|root,COG5002@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,1PGCN@1224|Proteobacteria,42ZJ2@68525|delta/epsilon subdivisions,2WUYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
DTH3_k127_4752961_9	234267.Acid_7815	2.454e-22	100.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria	57723|Acidobacteria	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
DTH3_k127_4752961_6	478741.JAFS01000001_gene1116	2.706e-65	241.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
DTH3_k127_4752961_4	234267.Acid_4382	7.255e-76	265.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DTH3_k127_4752961_0	234267.Acid_5590	2.09e-160	526.0	COG0843@1|root,COG0843@2|Bacteria,3Y2NS@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DTH3_k127_4752961_3	481448.Minf_1950	1.248e-85	291.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DTH3_k127_4752961_10	1396141.BATP01000045_gene1834	4.483e-08	60.0	2DR0H@1|root,339NS@2|Bacteria,46ZIA@74201|Verrucomicrobia,2IUYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
DTH3_k127_4752961_5	497964.CfE428DRAFT_2235	7.857e-69	242.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
DTH3_k127_4752961_8	478741.JAFS01000002_gene875	1.23e-30	129.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DTH3_k127_4752961_7	521674.Plim_0216	1.082e-31	129.0	COG1999@1|root,COG2322@1|root,COG1999@2|Bacteria,COG2322@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
DTH3_k127_4752961_2	313612.L8106_20308	7.199e-86	296.0	COG4301@1|root,COG4301@2|Bacteria,1G4VW@1117|Cyanobacteria,1HF60@1150|Oscillatoriales	1117|Cyanobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
DTH3_k127_4752961_1	533247.CRD_00431	8.216e-118	386.0	COG0294@1|root,COG0720@1|root,COG0294@2|Bacteria,COG0720@2|Bacteria,1GKBI@1117|Cyanobacteria,1HSIJ@1161|Nostocales	1117|Cyanobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DTH3_k127_4753414_0	234267.Acid_7728	4.023e-107	355.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
DTH3_k127_4753414_1	118173.KB235914_gene3105	4.232e-41	158.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
DTH3_k127_4754478_2	1249975.JQLP01000005_gene2306	4.706e-67	259.0	COG4258@1|root,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1HYZW@117743|Flavobacteriia,2P5PX@244698|Gillisia	976|Bacteroidetes	I	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
DTH3_k127_4754478_1	1123008.KB905694_gene1758	9.431e-74	267.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,2FQIT@200643|Bacteroidia,22X2B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
DTH3_k127_4754478_0	338966.Ppro_0910	2.434e-98	332.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42QET@68525|delta/epsilon subdivisions,2WIZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
DTH3_k127_4763201_0	497964.CfE428DRAFT_4519	5.413e-77	266.0	COG0388@1|root,COG0388@2|Bacteria,46T1B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
DTH3_k127_4763201_1	204669.Acid345_3346	3.76e-33	137.0	2E0G4@1|root,32W27@2|Bacteria	2|Bacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
DTH3_k127_4763201_3	1201288.M900_1405	9.831e-16	88.0	COG1280@1|root,COG1280@2|Bacteria,1N227@1224|Proteobacteria,43DA6@68525|delta/epsilon subdivisions,2WVZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
DTH3_k127_4763201_2	240016.ABIZ01000001_gene3412	2.754e-23	103.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,2ITHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DTH3_k127_4765843_1	1396141.BATP01000056_gene3118	4.477e-59	216.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,2IWN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
DTH3_k127_4765843_0	382464.ABSI01000010_gene3853	1.677e-62	226.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DTH3_k127_4765843_3	452637.Oter_1848	0.000958	45.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH3_k127_4765843_2	452637.Oter_1848	3.002e-05	48.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH3_k127_4767983_0	1499967.BAYZ01000095_gene4126	1.699e-208	655.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
DTH3_k127_4767983_2	314345.SPV1_00507	3.429e-21	98.0	COG2192@1|root,COG2192@2|Bacteria,1R3MX@1224|Proteobacteria	1224|Proteobacteria	O	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4767983_3	439235.Dalk_4189	8.608e-17	92.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_4767983_4	1191523.MROS_1643	2.13e-12	69.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4767983_1	497964.CfE428DRAFT_2202	5.221e-44	182.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
DTH3_k127_4767983_5	889378.Spiaf_1773	6.601e-08	63.0	COG2885@1|root,COG4254@1|root,COG2885@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	1.9.3.1	ko:K02275,ko:K03286	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.6,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Big_2,COX2,COX2_TM,FecR,OmpA,TPR_16,fn3
DTH3_k127_4767983_6	1499967.BAYZ01000131_gene368	2.847e-05	56.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
DTH3_k127_4771568_8	1089550.ATTH01000001_gene1221	4.639e-33	130.0	COG2267@1|root,COG2267@2|Bacteria,4PKJZ@976|Bacteroidetes,1FIMU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DTH3_k127_4771568_6	240016.ABIZ01000001_gene5350	4.079e-64	230.0	COG3267@1|root,COG3267@2|Bacteria,46XMZ@74201|Verrucomicrobia,2IW82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
DTH3_k127_4771568_7	240016.ABIZ01000001_gene5349	1.644e-44	184.0	COG1596@1|root,COG3206@1|root,COG1596@2|Bacteria,COG3206@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
DTH3_k127_4771568_2	1123070.KB899258_gene1891	9.653e-88	310.0	COG1596@1|root,COG1596@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
DTH3_k127_4771568_3	240016.ABIZ01000001_gene5347	2.286e-85	295.0	COG1596@1|root,COG1596@2|Bacteria,46XCW@74201|Verrucomicrobia,2IVGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
DTH3_k127_4771568_0	497964.CfE428DRAFT_1569	4.222e-190	612.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH3_k127_4771568_9	1117108.PAALTS15_19168	2.146e-08	64.0	COG0726@1|root,COG3291@1|root,COG5184@1|root,COG5276@1|root,COG5434@1|root,COG0726@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5434@2|Bacteria,1UYD0@1239|Firmicutes,4HVHQ@91061|Bacilli,26U3Z@186822|Paenibacillaceae	91061|Bacilli	M	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C
DTH3_k127_4771568_1	1149133.ppKF707_4753	2.841e-129	439.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RYKY@1236|Gammaproteobacteria,1YFQD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH3_k127_4771568_4	240016.ABIZ01000001_gene5833	8.898e-82	287.0	COG0642@1|root,COG2205@2|Bacteria,46V7H@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DTH3_k127_4771568_5	1403819.BATR01000112_gene3842	3.557e-74	258.0	COG0745@1|root,COG0745@2|Bacteria	1403819.BATR01000112_gene3842|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4773123_0	583355.Caka_3109	2.886e-218	714.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
DTH3_k127_4786524_3	1168034.FH5T_01555	1.51e-87	299.0	COG0348@1|root,COG0348@2|Bacteria,4NPVD@976|Bacteroidetes,2FTEY@200643|Bacteroidia	976|Bacteroidetes	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
DTH3_k127_4786524_4	1168034.FH5T_01560	5.044e-69	240.0	2DVMZ@1|root,33WFQ@2|Bacteria,4P3VR@976|Bacteroidetes,2FXVM@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	-
DTH3_k127_4786524_5	595460.RRSWK_06184	7.809e-48	184.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
DTH3_k127_4786524_1	595460.RRSWK_06183	4.467e-115	387.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_4786524_2	452637.Oter_3509	5.408e-89	310.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_4786524_6	1123242.JH636434_gene5340	1.359e-37	162.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_4786524_0	272134.KB731324_gene3214	5.118e-192	619.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria,1H8JB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3471,PD40,Peptidase_S9,Peptidase_S9_N
DTH3_k127_4802173_1	497964.CfE428DRAFT_5668	7.251e-45	184.0	COG0457@1|root,COG0457@2|Bacteria,46V4J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_8
DTH3_k127_4802173_0	497964.CfE428DRAFT_5666	6.993e-118	388.0	COG0040@1|root,COG0040@2|Bacteria,46SHK@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Histidine biosynthesis protein HisG domain	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
DTH3_k127_4802173_2	644966.Tmar_1419	3.956e-35	136.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3WCM0@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
DTH3_k127_4802341_0	452637.Oter_0123	2.991e-152	501.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
DTH3_k127_4802341_3	794903.OPIT5_24500	5.419e-103	343.0	COG0657@1|root,COG0657@2|Bacteria,46VDF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
DTH3_k127_4802341_2	452637.Oter_2206	4.581e-108	356.0	COG1136@1|root,COG1136@2|Bacteria,46SAX@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_4802341_1	240016.ABIZ01000001_gene5721	8.263e-130	434.0	COG0577@1|root,COG0577@2|Bacteria,46S5D@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_4803465_6	1231185.BAMP01000071_gene3347	3.752e-10	66.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,43GVF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	deoD	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DTH3_k127_4803465_2	497964.CfE428DRAFT_5353	1.038e-27	127.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH3_k127_4803465_4	1123248.KB893324_gene1755	6.637e-15	87.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH3_k127_4803465_3	471223.GWCH70_1512	3.284e-21	100.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1WEX0@129337|Geobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
DTH3_k127_4803465_7	1273125.Rrhod_2956	0.0003437	49.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FUXM@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
DTH3_k127_4803465_1	935948.KE386494_gene695	9.37e-147	489.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
DTH3_k127_4803465_5	1123242.JH636435_gene2068	1.813e-12	80.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_4803465_0	497964.CfE428DRAFT_5737	2.922e-199	628.0	COG0673@1|root,COG0673@2|Bacteria,46UQI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_4806132_0	246194.CHY_1785	1.218e-94	317.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,42EJV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DTH3_k127_4806132_1	644801.Psest_3899	1.394e-42	163.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,1Z115@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	phosphoribosyltransferases	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
DTH3_k127_4806132_2	926550.CLDAP_00200	2.776e-40	159.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
DTH3_k127_4822111_4	1123508.JH636442_gene3883	1.735e-21	108.0	COG3779@1|root,COG3779@2|Bacteria,2J1PD@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314
DTH3_k127_4822111_1	1121335.Clst_0783	1.51e-180	571.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
DTH3_k127_4822111_6	469383.Cwoe_4336	6.301e-09	65.0	2B4AG@1|root,31X1X@2|Bacteria,2GWKS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4822111_0	314230.DSM3645_26339	6.275e-194	614.0	COG2755@1|root,COG2755@2|Bacteria,2IYT9@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Lipase_GDSL_2
DTH3_k127_4822111_3	1385518.N798_14125	1.37e-34	137.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4FH30@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DTH3_k127_4822111_2	1396418.BATQ01000092_gene5859	3.807e-104	349.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
DTH3_k127_4822111_5	1396141.BATP01000042_gene1908	1.06e-15	76.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DTH3_k127_482289_1	1142394.PSMK_18030	0.0001603	46.0	COG3119@1|root,COG3119@2|Bacteria,2IYMC@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
DTH3_k127_482289_0	1140.Synpcc7942_0722	4.492e-45	179.0	28JXH@1|root,2ZA3Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RecT
DTH3_k127_4845811_2	344747.PM8797T_11389	1.541e-121	397.0	COG1172@1|root,COG1172@2|Bacteria,2IZWQ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K10559,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
DTH3_k127_4845811_0	344747.PM8797T_11384	4.234e-188	599.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	2|Bacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA_3	-	3.6.3.17	ko:K10441,ko:K17210	ko02010,map02010	M00212,M00592	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21	-	-	ABC_tran
DTH3_k127_4845811_1	344747.PM8797T_11379	3.309e-130	424.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
DTH3_k127_4845811_3	797209.ZOD2009_14571	1.75e-67	258.0	COG1621@1|root,arCOG08134@2157|Archaea,2XUXA@28890|Euryarchaeota,23UA6@183963|Halobacteria	183963|Halobacteria	G	COG1621 Beta-fructosidases (levanase invertase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
DTH3_k127_4845811_5	1403819.BATR01000164_gene5643	1.173e-16	95.0	COG2010@1|root,COG2010@2|Bacteria,46V0R@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
DTH3_k127_4845811_7	1303518.CCALI_01840	1.243e-12	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_4845811_6	1227352.C173_18071	1.126e-12	72.0	COG0697@1|root,COG0697@2|Bacteria,1VP2K@1239|Firmicutes,4I1UM@91061|Bacilli,26WQN@186822|Paenibacillaceae	91061|Bacilli	EG	Protein of unknown function (DUF2569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569
DTH3_k127_4845811_8	1340493.JNIF01000003_gene2695	7.105e-08	62.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4845811_10	1340493.JNIF01000003_gene2695	2.599e-05	49.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4845811_11	278957.ABEA03000117_gene1086	0.0001264	56.0	COG3664@1|root,COG3664@2|Bacteria,46XQU@74201|Verrucomicrobia,3K962@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4845811_12	979556.MTES_1035	0.0001665	56.0	COG3664@1|root,COG3664@2|Bacteria,2IAP4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_cc
DTH3_k127_4845811_9	324057.Pjdr2_1173	8.086e-06	60.0	COG3664@1|root,COG5434@1|root,COG5520@1|root,COG3664@2|Bacteria,COG5434@2|Bacteria,COG5520@2|Bacteria,1VC96@1239|Firmicutes,4HV2Q@91061|Bacilli,2774T@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Big_4,CBM9_1,Pectate_lyase_3,SLH
DTH3_k127_4846662_3	1168034.FH5T_01595	1.071e-80	287.0	COG1520@1|root,COG1520@2|Bacteria,4P28I@976|Bacteroidetes,2FX0J@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_4846662_1	673860.AciM339_1573	7.028e-90	310.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
DTH3_k127_4846662_0	880072.Desac_1581	8.004e-202	641.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MR7G@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH3_k127_4846662_2	264732.Moth_0141	2.005e-83	289.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
DTH3_k127_4846662_4	583355.Caka_1868	7.605e-41	155.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,3K871@414999|Opitutae	414999|Opitutae	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
DTH3_k127_4846662_6	1463821.JOGR01000002_gene431	1.424e-19	94.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4EYKI@85014|Glycomycetales	201174|Actinobacteria	G	Glycerate kinase family	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
DTH3_k127_4880026_1	452637.Oter_0818	1.864e-253	785.0	COG0334@1|root,COG0334@2|Bacteria,46UBX@74201|Verrucomicrobia,3K7SK@414999|Opitutae	414999|Opitutae	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH3_k127_4880026_0	452637.Oter_0819	1.866e-279	872.0	COG0574@1|root,COG0574@2|Bacteria,46XFR@74201|Verrucomicrobia,3K763@414999|Opitutae	414999|Opitutae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
DTH3_k127_4883008_3	690850.Desaf_1399	3.476e-51	199.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,43ESD@68525|delta/epsilon subdivisions,2X9MI@28221|Deltaproteobacteria,2MF6N@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
DTH3_k127_4883008_2	497964.CfE428DRAFT_5778	3.124e-102	344.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
DTH3_k127_4883008_1	1304885.AUEY01000019_gene1169	1.136e-135	457.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DTH3_k127_4883008_4	926566.Terro_1693	5.692e-17	88.0	COG2823@1|root,COG2823@2|Bacteria,3Y4FV@57723|Acidobacteria,2JJ5I@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
DTH3_k127_4883008_0	1123242.JH636435_gene2020	8.23e-271	842.0	COG2407@1|root,COG2407@2|Bacteria,2IXT8@203682|Planctomycetes	203682|Planctomycetes	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4886899_2	314230.DSM3645_20627	9.423e-62	218.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_4886899_1	497964.CfE428DRAFT_0022	1.551e-80	275.0	COG0217@1|root,COG0217@2|Bacteria,46SMV@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DTH3_k127_4886899_0	240016.ABIZ01000001_gene4136	1.239e-286	895.0	COG2010@1|root,COG3241@1|root,COG2010@2|Bacteria,COG3241@2|Bacteria	2|Bacteria	C	Transfers electrons from cytochrome c551 to cytochrome oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
DTH3_k127_4889556_2	880074.BARVI_00060	9.197e-10	70.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,2FQDN@200643|Bacteroidia,230V3@171551|Porphyromonadaceae	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
DTH3_k127_4889556_0	331869.BAL199_23067	3.824e-33	130.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,4BSRA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
DTH3_k127_4889556_1	926569.ANT_30650	1.146e-31	126.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
DTH3_k127_4896093_4	1392498.JQLH01000001_gene3450	0.0001496	44.0	2DNXG@1|root,32ZNF@2|Bacteria,4NV9Z@976|Bacteroidetes,1I563@117743|Flavobacteriia,2PHTT@252356|Maribacter	976|Bacteroidetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
DTH3_k127_4896093_2	118173.KB235914_gene1673	4.66e-09	61.0	COG5548@1|root,COG5548@2|Bacteria,1G997@1117|Cyanobacteria,1HCVD@1150|Oscillatoriales	1117|Cyanobacteria	S	Transmembrane proteins 14C	-	-	-	-	-	-	-	-	-	-	-	-	Tmemb_14
DTH3_k127_4896093_0	28072.Nos7524_4621	1.857e-22	113.0	COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales	1117|Cyanobacteria	MU	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,He_PIG,RHS_repeat
DTH3_k127_4896093_1	84531.JMTZ01000014_gene2710	4.908e-13	83.0	COG2385@1|root,COG4632@1|root,COG2385@2|Bacteria,COG4632@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	tagL	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Amidase_3,Big_2,ChW,DUF4988,NAGPA,SLH,SpoIID
DTH3_k127_490032_2	1519464.HY22_00765	3.136e-60	214.0	COG0533@1|root,COG0533@2|Bacteria,1FDD5@1090|Chlorobi	1090|Chlorobi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DTH3_k127_490032_1	497964.CfE428DRAFT_2715	2.907e-124	412.0	COG0793@1|root,COG0793@2|Bacteria,46SM7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
DTH3_k127_490032_0	497964.CfE428DRAFT_0809	1.096e-177	565.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4914344_2	404589.Anae109_3641	2.444e-06	58.0	2E3NC@1|root,32YKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4914344_0	344747.PM8797T_21498	1.196e-158	527.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
DTH3_k127_4914344_1	485913.Krac_10089	4.186e-80	274.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
DTH3_k127_491918_2	980584.AFPB01000131_gene3192	5.977e-07	63.0	COG2730@1|root,COG3401@1|root,COG2730@2|Bacteria,COG3401@2|Bacteria,4PPCW@976|Bacteroidetes,1I8FJ@117743|Flavobacteriia,4079T@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_491918_1	768706.Desor_4071	1.14e-71	258.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,260EI@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH3_k127_491918_0	497964.CfE428DRAFT_4093	6.249e-242	760.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia	74201|Verrucomicrobia	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
DTH3_k127_4937614_2	1142394.PSMK_15610	1.794e-39	167.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DTH3_k127_4937614_4	1487923.DP73_10970	1.05e-33	141.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
DTH3_k127_4937614_6	1125863.JAFN01000001_gene727	1.726e-27	125.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
DTH3_k127_4937614_0	313628.LNTAR_12671	1.924e-184	598.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
DTH3_k127_4937614_1	313628.LNTAR_12676	1.163e-109	367.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_4937614_7	383372.Rcas_3764	7.552e-06	58.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
DTH3_k127_4937614_3	313628.LNTAR_20703	2.783e-39	166.0	COG3147@1|root,COG3147@2|Bacteria	2|Bacteria	S	peptidoglycan binding	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DUF3108,SPOR
DTH3_k127_4937614_5	867903.ThesuDRAFT_02283	6.808e-32	130.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WCD6@538999|Clostridiales incertae sedis	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DTH3_k127_4946149_2	1267535.KB906767_gene2459	8.979e-93	312.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,DUF4832,DUF4978,FIVAR,Glyco_hydro_42,Glyco_hydro_42M
DTH3_k127_4946149_0	583355.Caka_3109	1.776e-219	745.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
DTH3_k127_4946149_3	573061.Clocel_1966	1.959e-39	172.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DTH3_k127_4946149_5	1396141.BATP01000007_gene5656	5.584e-07	64.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4946149_4	1303518.CCALI_02038	1.507e-16	89.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_4946149_1	886293.Sinac_4751	9.564e-105	353.0	COG0584@1|root,COG0584@2|Bacteria,2IXVA@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH3_k127_4948361_1	1123277.KB893193_gene3895	4.437e-130	422.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
DTH3_k127_4948361_0	330214.NIDE3012	1.905e-160	511.0	COG1089@1|root,COG1089@2|Bacteria,3J0YR@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH3_k127_4948361_2	886293.Sinac_0400	8.123e-106	354.0	COG4249@1|root,COG4249@2|Bacteria,2IZ2A@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_496165_5	497964.CfE428DRAFT_0775	6.615e-54	192.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH3_k127_496165_1	886293.Sinac_0405	6.448e-156	498.0	COG0714@1|root,COG0714@2|Bacteria,2IX8Y@203682|Planctomycetes	203682|Planctomycetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH3_k127_496165_2	344747.PM8797T_32255	2.685e-110	363.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
DTH3_k127_496165_0	497964.CfE428DRAFT_0772	1.937e-248	797.0	COG0457@1|root,COG0457@2|Bacteria,46U9B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_19
DTH3_k127_496165_3	521674.Plim_3779	1.7e-109	370.0	COG2755@1|root,COG2755@2|Bacteria,2IZBK@203682|Planctomycetes	203682|Planctomycetes	E	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase
DTH3_k127_496165_4	204669.Acid345_4052	6.618e-102	344.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
DTH3_k127_4972754_6	1094466.KQS_00160	2.418e-07	56.0	COG4783@1|root,COG4783@2|Bacteria,4NP8B@976|Bacteroidetes,1IKK5@117743|Flavobacteriia,2NVJS@237|Flavobacterium	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH3_k127_4972754_5	278957.ABEA03000176_gene2840	5.885e-25	107.0	COG4309@1|root,COG4309@2|Bacteria,46XTU@74201|Verrucomicrobia,3K814@414999|Opitutae	414999|Opitutae	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
DTH3_k127_4972754_4	1051632.TPY_0746	1.347e-30	126.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,24VD9@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH3_k127_4972754_2	671143.DAMO_1688	1.356e-80	287.0	COG3278@1|root,COG3278@2|Bacteria,2NRHY@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4972754_3	671143.DAMO_1689	2.969e-31	131.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
DTH3_k127_4972754_0	497964.CfE428DRAFT_0970	1.345e-249	793.0	COG0457@1|root,COG0457@2|Bacteria,46UPB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_8
DTH3_k127_4972754_1	234267.Acid_4959	1.115e-108	380.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y63K@57723|Acidobacteria	57723|Acidobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
DTH3_k127_4979581_0	1123242.JH636438_gene5875	5.457e-144	464.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_4979581_1	382464.ABSI01000013_gene1546	2.394e-23	110.0	COG5036@1|root,COG5036@2|Bacteria,46VA7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH3_k127_4979581_2	1144932.ATTF01000017_gene1171	9.049e-23	107.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
DTH3_k127_4979581_3	414684.RC1_4050	0.0001548	53.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
DTH3_k127_4993101_3	1303518.CCALI_02173	8.661e-10	69.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_4993101_2	1499967.BAYZ01000095_gene4068	8.367e-18	96.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_4993101_0	1267534.KB906755_gene4821	1.278e-176	577.0	COG3345@1|root,COG3345@2|Bacteria,3Y44J@57723|Acidobacteria,2JIVW@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4993101_1	929713.NIASO_11325	7.163e-37	157.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes	976|Bacteroidetes	G	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
DTH3_k127_4993176_0	497964.CfE428DRAFT_2824	0.0	2482.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_4993176_1	497964.CfE428DRAFT_2825	1.59e-171	545.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46TEF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Von Willebrand factor	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,VWA_3,vWF_A
DTH3_k127_4993751_2	1492737.FEM08_10420	3.009e-82	285.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IJTV@117743|Flavobacteriia,2NVD2@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH3_k127_4993751_5	391596.PBAL39_10776	2.852e-46	171.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,1ISZ2@117747|Sphingobacteriia	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
DTH3_k127_4993751_3	1123073.KB899241_gene3101	3.992e-82	281.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1XCBQ@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH3_k127_4993751_0	1121904.ARBP01000032_gene2006	2.257e-174	584.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,47RDC@768503|Cytophagia	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
DTH3_k127_4993751_1	1142394.PSMK_04700	2.306e-167	545.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
DTH3_k127_4993751_4	349521.HCH_05416	3.573e-58	214.0	COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,1RN60@1236|Gammaproteobacteria,1XJ0F@135619|Oceanospirillales	135619|Oceanospirillales	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
DTH3_k127_4993751_6	1218352.B597_016335	0.0002294	44.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RS50@1236|Gammaproteobacteria,1Z0W7@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	tauC	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
DTH3_k127_4994790_4	240016.ABIZ01000001_gene428	1.62e-71	246.0	COG1403@1|root,COG1403@2|Bacteria,46UDR@74201|Verrucomicrobia,2IUK8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_4
DTH3_k127_4994790_1	1396418.BATQ01000161_gene5597	3.815e-119	389.0	COG1423@1|root,COG1423@2|Bacteria	2|Bacteria	L	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
DTH3_k127_4994790_0	344747.PM8797T_22613	3.547e-152	491.0	COG4639@1|root,COG4639@2|Bacteria,2IZ4C@203682|Planctomycetes	203682|Planctomycetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,HD
DTH3_k127_4994790_2	497964.CfE428DRAFT_2414	6.701e-98	336.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
DTH3_k127_4994790_3	497964.CfE428DRAFT_3817	2.788e-83	284.0	COG1690@1|root,COG1690@2|Bacteria,46SU0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
DTH3_k127_500004_0	616991.JPOO01000001_gene2853	8.133e-89	307.0	COG4409@1|root,COG4409@2|Bacteria,4PAPR@976|Bacteroidetes,1IF7B@117743|Flavobacteriia,23HKK@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_500004_1	1123288.SOV_1c06670	7.421e-30	126.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H33H@909932|Negativicutes	909932|Negativicutes	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
DTH3_k127_5002321_0	497964.CfE428DRAFT_2824	1.044e-100	335.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5002321_1	269799.Gmet_2492	9.44e-60	215.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
DTH3_k127_5002321_4	236097.ADG881_2747	1.371e-34	138.0	COG0346@1|root,COG0346@2|Bacteria,1N8P0@1224|Proteobacteria,1SGYP@1236|Gammaproteobacteria,1XPDJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH3_k127_5002321_2	671143.DAMO_0981	8.214e-59	209.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH3_k127_5030759_0	478741.JAFS01000002_gene849	2.265e-173	554.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia,37G3K@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH3_k127_5046587_1	240016.ABIZ01000001_gene1770	1.212e-24	106.0	COG0580@1|root,COG0580@2|Bacteria,46V4W@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Major intrinsic protein	-	-	-	-	-	-	-	-	-	-	-	-	MIP
DTH3_k127_5046587_3	1487923.DP73_02105	2.1e-13	76.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,2609M@186807|Peptococcaceae	186801|Clostridia	F	TIGRFAM Pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
DTH3_k127_5046587_2	1117319.PSPO_04287	3.016e-15	79.0	COG1520@1|root,COG1520@2|Bacteria,1N8KC@1224|Proteobacteria,1SF02@1236|Gammaproteobacteria,2Q4VQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_5046587_0	635013.TherJR_2071	2.029e-125	407.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH3_k127_5048219_0	639282.DEFDS_1034	1.51e-53	199.0	COG0854@1|root,COG0854@2|Bacteria,2GEZZ@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DTH3_k127_5048219_2	903814.ELI_3081	1.987e-18	92.0	COG1408@1|root,COG5652@1|root,COG1408@2|Bacteria,COG5652@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,25X0Z@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DTH3_k127_5048219_3	383372.Rcas_3433	6.908e-15	85.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,375B1@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
DTH3_k127_5048219_1	883126.HMPREF9710_02976	8.882e-48	175.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
DTH3_k127_5048219_4	497964.CfE428DRAFT_2383	3.709e-08	61.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5061764_2	886293.Sinac_6493	3.998e-90	311.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH3_k127_5061764_3	1396141.BATP01000024_gene851	6.181e-19	90.0	2EM29@1|root,33ERR@2|Bacteria,46WJK@74201|Verrucomicrobia,2IWEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5061764_4	913325.N799_06220	1.844e-12	79.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria,1X406@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH3_k127_5061764_1	1396141.BATP01000024_gene848	4.693e-166	540.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
DTH3_k127_5061764_0	1396141.BATP01000024_gene849	2.195e-182	574.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
DTH3_k127_5066325_0	684949.ATTJ01000001_gene2613	5.433e-115	381.0	COG3842@1|root,COG3842@2|Bacteria,1WIWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
DTH3_k127_5066325_1	321327.CYA_1858	1.343e-86	295.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,1H1QV@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
DTH3_k127_5066325_2	321332.CYB_2209	4.624e-32	132.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria,1H1XK@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
DTH3_k127_5077978_8	583355.Caka_1216	1.51e-07	52.0	COG2151@1|root,COG2151@2|Bacteria,46VI1@74201|Verrucomicrobia,3K7B6@414999|Opitutae	414999|Opitutae	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DTH3_k127_5077978_9	240016.ABIZ01000001_gene2614	1.346e-06	63.0	COG2373@1|root,COG2885@1|root,COG3210@1|root,COG5563@1|root,COG2373@2|Bacteria,COG2885@2|Bacteria,COG3210@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.1.4.3	ko:K01114,ko:K12287,ko:K15125,ko:K16191,ko:K20276	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,ko05133,map00562,map00564,map00565,map01100,map01110,map02024,map04919,map05133	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko00536,ko01000,ko02000,ko02042,ko02044	1.B.6.1.3	-	-	DUF1573,OmpA
DTH3_k127_5077978_3	1121904.ARBP01000023_gene4986	6.827e-105	388.0	COG3210@1|root,COG4886@1|root,COG4935@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,Flg_new,Glug,LRR_5,PKD,P_proprotein,SprB
DTH3_k127_5077978_6	1116472.MGMO_57c00190	1.565e-10	76.0	COG0028@1|root,COG3291@1|root,COG0028@2|Bacteria,COG3291@2|Bacteria,1R1H9@1224|Proteobacteria,1T52V@1236|Gammaproteobacteria,1XEUH@135618|Methylococcales	2|Bacteria	EH	Fibronectin type 3 domain	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF5017,DUF5050,Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
DTH3_k127_5077978_4	429009.Adeg_0968	2.72e-90	317.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
DTH3_k127_5077978_1	639282.DEFDS_0642	3.893e-123	411.0	COG0318@1|root,COG0318@2|Bacteria,2GETC@200930|Deferribacteres	200930|Deferribacteres	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DTH3_k127_5077978_7	1131266.ARWQ01000091_gene18	5.691e-10	63.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5077978_0	497964.CfE428DRAFT_2462	3.82e-145	469.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Nucleoside diphosphate kinase	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DTH3_k127_5077978_5	671143.DAMO_2861	4.145e-35	141.0	COG0494@1|root,COG0494@2|Bacteria,2NPUY@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
DTH3_k127_5077978_2	481448.Minf_0010	6.502e-106	349.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH3_k127_509551_2	391587.KAOT1_04150	1.054e-30	144.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,PQQ_2
DTH3_k127_509551_4	195250.CM001776_gene1220	1.343e-07	67.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,1GJ0D@1117|Cyanobacteria,1H29D@1129|Synechococcus	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat,SdrD_B
DTH3_k127_509551_1	856793.MICA_147	4.212e-53	218.0	COG1520@1|root,COG1520@2|Bacteria,1R0E4@1224|Proteobacteria,2UJBQ@28211|Alphaproteobacteria,4BSD7@82117|unclassified Alphaproteobacteria	1224|Proteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
DTH3_k127_509551_0	99598.Cal7507_3395	6.252e-98	366.0	COG1520@1|root,COG1520@2|Bacteria,1GHEB@1117|Cyanobacteria,1HKIG@1161|Nostocales	1117|Cyanobacteria	C	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PPC
DTH3_k127_509551_3	91464.S7335_5095	2.707e-21	113.0	COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,1H0CR@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,FG-GAP,HemolysinCabind
DTH3_k127_5112808_2	497964.CfE428DRAFT_1869	1.285e-31	125.0	COG1899@1|root,COG1899@2|Bacteria,46T9G@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DTH3_k127_5112808_0	204669.Acid345_0011	4.602e-164	530.0	COG5316@1|root,COG5316@2|Bacteria,3Y4FP@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
DTH3_k127_5112808_1	237368.SCABRO_03057	2.255e-77	275.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
DTH3_k127_5112808_3	1123508.JH636439_gene1468	1.141e-07	58.0	COG0515@1|root,COG3642@1|root,COG0515@2|Bacteria,COG3642@2|Bacteria,2IZTN@203682|Planctomycetes	203682|Planctomycetes	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
DTH3_k127_5121407_0	385682.AFSL01000012_gene2848	1.267e-122	413.0	COG3401@1|root,COG3401@2|Bacteria,4NFM5@976|Bacteroidetes,2FPSM@200643|Bacteroidia	976|Bacteroidetes	S	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
DTH3_k127_5121407_1	485913.Krac_6839	6.564e-74	259.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
DTH3_k127_5121407_2	671143.DAMO_2488	1.355e-38	155.0	COG1459@1|root,COG1459@2|Bacteria,2NP2J@2323|unclassified Bacteria	2|Bacteria	U	Type II secretion system (T2SS), protein F	xpsF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
DTH3_k127_5122882_2	243090.RB11088	6.911e-17	84.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DTH3_k127_5122882_0	382464.ABSI01000011_gene2813	1.177e-108	362.0	COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
DTH3_k127_5122882_1	1122604.JONR01000033_gene34	6.3e-50	185.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH3_k127_5125319_0	1121924.ATWH01000017_gene3159	2.896e-33	149.0	COG3408@1|root,COG3408@2|Bacteria,2GYU2@201174|Actinobacteria,4FR4D@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl-hydrolase family 116, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DUF608
DTH3_k127_5137101_4	118005.AWNK01000001_gene2050	3.591e-44	164.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	purD	-	6.3.2.6,6.3.4.13,6.3.5.3	ko:K01945,ko:K01952,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04463,R04591	RC00010,RC00064,RC00090,RC00162,RC00166,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
DTH3_k127_5137101_6	661478.OP10G_4802	1.684e-14	83.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_5137101_2	344747.PM8797T_07504	6.24e-71	250.0	COG0428@1|root,COG0428@2|Bacteria,2IZ3C@203682|Planctomycetes	203682|Planctomycetes	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
DTH3_k127_5137101_3	517418.Ctha_1767	2.322e-67	237.0	COG2755@1|root,COG2755@2|Bacteria,1FET3@1090|Chlorobi	1090|Chlorobi	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
DTH3_k127_5137101_1	1121957.ATVL01000008_gene3992	5.79e-94	315.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_5137101_0	452637.Oter_0071	4.158e-222	717.0	COG3127@1|root,COG3127@2|Bacteria,46UKQ@74201|Verrucomicrobia,3K7U2@414999|Opitutae	414999|Opitutae	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_5137101_5	344747.PM8797T_25041	1.413e-19	95.0	COG1082@1|root,COG1082@2|Bacteria,2IXXX@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_5137727_0	521674.Plim_2538	1.704e-177	574.0	COG1506@1|root,COG5306@1|root,COG1506@2|Bacteria,COG5306@2|Bacteria,2IYRT@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DTH3_k127_5137727_1	234267.Acid_4415	2.933e-126	412.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DTH3_k127_5138406_0	1869.MB27_10910	2.727e-92	313.0	COG1090@1|root,COG1090@2|Bacteria,2GU34@201174|Actinobacteria,4DH4S@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
DTH3_k127_5138406_2	240016.ABIZ01000001_gene5918	3.14e-16	89.0	2DS4P@1|root,33EH8@2|Bacteria,46XKS@74201|Verrucomicrobia,2IW5C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5138406_1	314230.DSM3645_07370	4.191e-36	142.0	295WE@1|root,2ZT7B@2|Bacteria,2J2RS@203682|Planctomycetes	203682|Planctomycetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
DTH3_k127_5140531_4	1396141.BATP01000024_gene849	4.228e-51	183.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
DTH3_k127_5140531_5	1403819.BATR01000123_gene4356	1.585e-32	138.0	28KDQ@1|root,2ZA05@2|Bacteria,46VJS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5140531_6	376686.Fjoh_2192	1.488e-09	67.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
DTH3_k127_5140531_1	926550.CLDAP_13850	1.44e-129	424.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	2|Bacteria	E	PFAM aminotransferase class V	phnW	GO:0003674,GO:0003824	2.5.1.49,2.6.1.37,3.11.1.1	ko:K01740,ko:K03430,ko:K05306	ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120	-	R00747,R01287,R04152,R04859	RC00008,RC00020,RC00062,RC00368,RC02821,RC02848	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
DTH3_k127_5140531_0	1122135.KB893134_gene3491	3.472e-131	432.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH3_k127_5140531_2	6500.XP_005099940.1	2.037e-116	381.0	COG0637@1|root,2QU58@2759|Eukaryota,39WII@33154|Opisthokonta,3BF9K@33208|Metazoa,3D4RC@33213|Bilateria	33208|Metazoa	S	Haloacid dehalogenase-like hydrolase	-	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
DTH3_k127_5140531_3	44056.XP_009033642.1	8.251e-87	291.0	COG0160@1|root,KOG1403@2759|Eukaryota	2759|Eukaryota	E	ethanolamine-phosphate phospho-lyase activity	-	-	4.2.3.2	ko:K14286	ko00564,ko01100,map00564,map01100	-	R00748	RC00369	ko00000,ko00001,ko01000	-	-	-	Aminotran_3,Peptidase_M23
DTH3_k127_5184874_0	748280.NH8B_1377	0.0	1222.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales	206351|Neisseriales	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
DTH3_k127_518907_2	1156937.MFUM_720038	1.889e-17	88.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,37GRB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DTH3_k127_518907_0	497964.CfE428DRAFT_4667	1.095e-179	573.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
DTH3_k127_518907_1	639030.JHVA01000001_gene2022	4.765e-42	164.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
DTH3_k127_5203933_1	1122931.AUAE01000008_gene4091	1.54e-165	550.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH3_k127_5203933_7	1123508.JH636439_gene975	7.022e-14	86.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_5203933_4	1077285.AGDG01000021_gene776	1.083e-83	288.0	COG1520@1|root,COG1520@2|Bacteria,4NM00@976|Bacteroidetes,2FR1A@200643|Bacteroidia,4ANP9@815|Bacteroidaceae	976|Bacteroidetes	S	unsaturated rhamnogalacturonyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,Glyco_hydro_88,PQQ_2
DTH3_k127_5203933_2	509191.AEDB02000002_gene1137	1.244e-105	380.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH3_k127_5203933_5	663610.JQKO01000019_gene3046	3.45e-23	117.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
DTH3_k127_5203933_3	509191.AEDB02000002_gene1137	4.098e-95	347.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH3_k127_5203933_6	663610.JQKO01000019_gene3046	4.635e-21	110.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
DTH3_k127_5203933_0	880526.KE386488_gene1576	1.235e-172	557.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5205663_1	398512.JQKC01000010_gene143	1.96e-108	368.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DTH3_k127_5205663_0	794903.OPIT5_05545	1.753e-133	443.0	COG0306@1|root,COG0306@2|Bacteria,46SDP@74201|Verrucomicrobia,3K7HD@414999|Opitutae	414999|Opitutae	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DTH3_k127_5205663_2	1121013.P873_11785	2.139e-72	247.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1X3YD@135614|Xanthomonadales	135614|Xanthomonadales	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DTH3_k127_5206945_3	96561.Dole_1704	1.392e-10	75.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5206945_2	583355.Caka_1736	3.522e-70	274.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_5206945_0	1396141.BATP01000034_gene4198	2.632e-290	964.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
DTH3_k127_5206945_1	1232410.KI421412_gene312	1.284e-123	416.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43RY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DTH3_k127_5211012_3	1121351.AUAP01000012_gene1234	2.984e-20	92.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KPYD@206351|Neisseriales	206351|Neisseriales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
DTH3_k127_5211012_2	497964.CfE428DRAFT_2087	7.675e-103	345.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia	74201|Verrucomicrobia	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
DTH3_k127_5211012_1	497964.CfE428DRAFT_2088	1.208e-195	615.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DTH3_k127_5211012_0	278957.ABEA03000091_gene684	7.447e-255	792.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH3_k127_5219907_1	756272.Plabr_3925	1.895e-85	291.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH3_k127_5219907_2	1396418.BATQ01000013_gene4380	1.295e-82	284.0	COG0515@1|root,COG0515@2|Bacteria,46UMT@74201|Verrucomicrobia,2IVH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,PG_binding_1,Pkinase
DTH3_k127_5219907_0	497964.CfE428DRAFT_0790	2.72e-188	599.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
DTH3_k127_5219907_3	639030.JHVA01000001_gene2022	4.005e-37	149.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
DTH3_k127_5223714_0	316274.Haur_3147	1.632e-07	64.0	COG1668@1|root,COG1668@2|Bacteria,2GBIJ@200795|Chloroflexi,3768Z@32061|Chloroflexia	32061|Chloroflexia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH3_k127_5223714_1	880071.Fleli_3575	0.000405	54.0	COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,47KPQ@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM Gliding motility-associated ABC transporter permease protein GldF	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
DTH3_k127_5235118_5	926550.CLDAP_26240	1.13e-38	154.0	COG3962@1|root,COG3962@2|Bacteria,2G68S@200795|Chloroflexi	200795|Chloroflexi	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH3_k127_5235118_2	485913.Krac_4319	2.724e-141	456.0	COG0524@1|root,COG0524@2|Bacteria,2G5XM@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DTH3_k127_5235118_4	649349.Lbys_0013	3.856e-107	355.0	COG3718@1|root,COG3718@2|Bacteria,4NKW4@976|Bacteroidetes,47TKD@768503|Cytophagia	976|Bacteroidetes	G	KduI/IolB family	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
DTH3_k127_5235118_3	481448.Minf_0287	3.903e-112	372.0	COG0191@1|root,COG0191@2|Bacteria,46TAJ@74201|Verrucomicrobia,37GA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
DTH3_k127_5235118_1	344747.PM8797T_29708	5.036e-180	573.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
DTH3_k127_5235118_0	794903.OPIT5_27205	1.123e-180	579.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia,3K77E@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DTH3_k127_5255652_5	452637.Oter_2031	1.106e-34	134.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DTH3_k127_5255652_6	452637.Oter_2032	3.362e-19	88.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
DTH3_k127_5255652_0	452637.Oter_2033	1.242e-256	798.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
DTH3_k127_5255652_4	452637.Oter_4232	2.237e-53	192.0	2F7MR@1|root,34028@2|Bacteria,46VN7@74201|Verrucomicrobia,3K85B@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5255652_3	497964.CfE428DRAFT_6227	1.577e-67	240.0	COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
DTH3_k127_5255652_1	697281.Mahau_1189	5.236e-221	717.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,42EMX@68295|Thermoanaerobacterales	186801|Clostridia	G	alpha-L-rhamnosidase domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH3_k127_5272119_0	1167006.UWK_00360	8.022e-105	357.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
DTH3_k127_5272119_1	269799.Gmet_1668	6.281e-44	166.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria,43VIR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
DTH3_k127_5272119_2	1237149.C900_03089	1.907e-15	80.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,4PNTS@976|Bacteroidetes,47YSC@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4
DTH3_k127_5275884_3	243090.RB8979	1.208e-20	93.0	COG1760@1|root,COG1760@2|Bacteria	2|Bacteria	E	l-serine dehydratase	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
DTH3_k127_5275884_1	1408813.AYMG01000036_gene3246	1.091e-59	212.0	COG0526@1|root,COG0526@2|Bacteria,4PIWE@976|Bacteroidetes,1IYSU@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5275884_0	1521187.JPIM01000083_gene3839	1.386e-75	269.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
DTH3_k127_5275884_2	357808.RoseRS_0192	5.921e-23	101.0	COG2154@1|root,COG2154@2|Bacteria,2G7GN@200795|Chloroflexi,375ZK@32061|Chloroflexia	32061|Chloroflexia	H	PFAM transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DTH3_k127_5275884_4	1048339.KB913029_gene1929	2.775e-20	101.0	2E37T@1|root,32Y7G@2|Bacteria,2HKTZ@201174|Actinobacteria,4EWSP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
DTH3_k127_5275884_5	452637.Oter_0732	5.936e-10	68.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
DTH3_k127_5311257_1	278963.ATWD01000001_gene2920	6.536e-96	316.0	2CK7V@1|root,2Z9WF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5311257_0	1396141.BATP01000003_gene4967	1.008e-208	679.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
DTH3_k127_5311257_2	314278.NB231_08217	5.891e-11	63.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,1WXY5@135613|Chromatiales	135613|Chromatiales	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
DTH3_k127_5313175_3	452637.Oter_3865	9.318e-60	213.0	COG0307@1|root,COG0307@2|Bacteria,46SU1@74201|Verrucomicrobia,3K7ZH@414999|Opitutae	414999|Opitutae	H	TIGRFAM riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
DTH3_k127_5313175_4	1132836.RCCGE510_07356	1.453e-46	172.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,4BE03@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
DTH3_k127_5313175_6	478741.JAFS01000001_gene1905	1.516e-37	146.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,37GQ9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
DTH3_k127_5313175_0	497964.CfE428DRAFT_2953	1.974e-200	634.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DTH3_k127_5313175_5	240015.ACP_2565	2.747e-46	171.0	COG0838@1|root,COG0838@2|Bacteria,3Y8B8@57723|Acidobacteria,2JN67@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH3_k127_5313175_1	1267534.KB906754_gene3780	1.973e-104	342.0	COG0377@1|root,COG0377@2|Bacteria,3Y74G@57723|Acidobacteria,2JKT1@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH3_k127_5313175_2	1267534.KB906754_gene3779	1.093e-89	303.0	COG0852@1|root,COG0852@2|Bacteria,3Y72R@57723|Acidobacteria,2JM53@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH3_k127_533722_0	1403819.BATR01000007_gene187	0.0	1119.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DTH3_k127_533722_2	497964.CfE428DRAFT_2480	4.888e-36	143.0	2AEIE@1|root,314DU@2|Bacteria,46WQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_533722_1	671143.DAMO_1527	1.06e-102	341.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DTH3_k127_5339723_0	886293.Sinac_5129	7.075e-145	463.0	COG4948@1|root,COG4948@2|Bacteria,2IXK2@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
DTH3_k127_5339723_1	497964.CfE428DRAFT_3487	1.009e-137	477.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
DTH3_k127_5339723_6	382464.ABSI01000013_gene1905	1.473e-13	77.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,2IURI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
DTH3_k127_5339723_4	240016.ABIZ01000001_gene908	1.661e-39	162.0	COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DTH3_k127_5339723_3	1156937.MFUM_920008	6.231e-48	175.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,37GI8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
DTH3_k127_5339723_2	641524.ADICYQ_2355	1.512e-93	331.0	COG4403@1|root,COG4403@2|Bacteria,4PMC1@976|Bacteroidetes,47Y49@768503|Cytophagia	976|Bacteroidetes	V	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH3_k127_5339723_5	1267535.KB906767_gene1118	6.013e-30	121.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria,2JJIJ@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
DTH3_k127_5341257_2	1396141.BATP01000056_gene3260	4.488e-12	81.0	COG2010@1|root,COG2133@1|root,COG2755@1|root,COG3209@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3209@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	74201|Verrucomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,GSDH,Laminin_G_3
DTH3_k127_5341257_3	682795.AciX8_3725	1.349e-11	79.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
DTH3_k127_5341257_1	309800.C498_02055	1.385e-14	89.0	arCOG05978@1|root,arCOG05978@2157|Archaea,2XU7Y@28890|Euryarchaeota,23SST@183963|Halobacteria	183963|Halobacteria	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5341257_5	1195236.CTER_5216	0.0001151	56.0	COG1572@1|root,COG3209@1|root,COG3210@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1TR9M@1239|Firmicutes,24BEI@186801|Clostridia,3WMNE@541000|Ruminococcaceae	186801|Clostridia	MU	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
DTH3_k127_5341257_4	479432.Sros_0936	1.22e-10	76.0	COG3188@1|root,COG3188@2|Bacteria,2HQZC@201174|Actinobacteria,4EFZ0@85012|Streptosporangiales	201174|Actinobacteria	NU	Glycosyl hydrolase family 48	cbhB	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_48
DTH3_k127_5341257_0	1379698.RBG1_1C00001G0608	6.188e-70	254.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
DTH3_k127_5341879_0	1121288.AULL01000013_gene1549	5.199e-20	104.0	COG5545@1|root,COG5545@2|Bacteria,4PMA3@976|Bacteroidetes,1IJP7@117743|Flavobacteriia,3ZSQA@59732|Chryseobacterium	976|Bacteroidetes	S	VirE N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987,PriCT_2,VirE,VirE_N
DTH3_k127_5341879_2	338969.Rfer_0682	9.201e-12	76.0	COG3468@1|root,COG5295@1|root,COG3468@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF3494,He_PIG
DTH3_k127_5341879_1	1123073.KB899242_gene1109	3.304e-13	76.0	COG1470@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Haemagg_act,He_PIG,Hint_2,TIG
DTH3_k127_5345145_1	314230.DSM3645_08622	8.576e-59	217.0	COG3391@1|root,COG3391@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
DTH3_k127_5345145_0	335541.Swol_1716	3.097e-85	303.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,249E6@186801|Clostridia	186801|Clostridia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
DTH3_k127_5345427_1	497964.CfE428DRAFT_1905	1.417e-107	358.0	COG1045@1|root,COG1045@2|Bacteria,46S5J@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
DTH3_k127_5345427_3	477641.MODMU_0790	2.278e-07	55.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2I81M@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
DTH3_k127_5345427_5	1121287.AUMU01000010_gene1804	0.0001981	55.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1IKPF@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
DTH3_k127_5345427_6	9713.XP_006733312.1	0.0001981	55.0	KOG0613@1|root,KOG4475@1|root,KOG0613@2759|Eukaryota,KOG4475@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata,48Y8I@7742|Vertebrata,3J1H6@40674|Mammalia,3EFX2@33554|Carnivora	33208|Metazoa	T	Titin Z	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
DTH3_k127_5345427_7	4555.Si032031m	0.0009014	46.0	COG1233@1|root,2QSIC@2759|Eukaryota,37N2T@33090|Viridiplantae,3GBKK@35493|Streptophyta,3KNEA@4447|Liliopsida,3ID4Z@38820|Poales	35493|Streptophyta	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
DTH3_k127_5345427_0	880073.Calab_3508	3.014e-122	402.0	COG1446@1|root,COG1446@2|Bacteria,2NPFC@2323|unclassified Bacteria	2|Bacteria	E	Asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DTH3_k127_5345427_4	595460.RRSWK_04420	2.104e-06	50.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
DTH3_k127_5350748_0	1121440.AUMA01000003_gene2931	9.908e-40	152.0	COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,42WA7@68525|delta/epsilon subdivisions,2WRWX@28221|Deltaproteobacteria,2MCC2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DTH3_k127_5350748_1	1385935.N836_19490	3.601e-25	119.0	COG3464@1|root,COG3464@2|Bacteria,1G9CU@1117|Cyanobacteria,1HGU0@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5350748_2	682795.AciX8_0881	1.665e-09	59.0	COG3250@1|root,COG3250@2|Bacteria,3Y6RC@57723|Acidobacteria,2JKAB@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_5367434_5	383372.Rcas_0560	6.118e-46	174.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
DTH3_k127_5367434_4	192952.MM_3371	2.368e-56	211.0	arCOG06820@1|root,arCOG06820@2157|Archaea,2XVYD@28890|Euryarchaeota,2N917@224756|Methanomicrobia	224756|Methanomicrobia	S	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	YoaP
DTH3_k127_5367434_7	1268237.G114_09454	7.207e-25	108.0	2EGMM@1|root,33ADT@2|Bacteria,1R0Q0@1224|Proteobacteria,1T4N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_4
DTH3_k127_5367434_3	481448.Minf_2259	5.879e-77	266.0	COG0084@1|root,COG0084@2|Bacteria,46SKF@74201|Verrucomicrobia,37GKS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DTH3_k127_5367434_0	497964.CfE428DRAFT_6291	3.339e-168	541.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
DTH3_k127_5367434_2	497964.CfE428DRAFT_2488	1.464e-78	285.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5367434_1	497964.CfE428DRAFT_2489	4.908e-83	283.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
DTH3_k127_5367434_6	497964.CfE428DRAFT_2490	1.141e-28	121.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
DTH3_k127_5380564_1	1267534.KB906758_gene2376	1.416e-184	584.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_5380564_0	497964.CfE428DRAFT_1607	0.0	1340.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DTH3_k127_5393657_11	1123242.JH636435_gene1239	2.801e-20	94.0	COG4576@1|root,COG4576@2|Bacteria,2J0UQ@203682|Planctomycetes	203682|Planctomycetes	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
DTH3_k127_5393657_0	452637.Oter_1295	4.293e-175	562.0	COG1012@1|root,COG1012@2|Bacteria,46UYV@74201|Verrucomicrobia,3K7HF@414999|Opitutae	414999|Opitutae	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
DTH3_k127_5393657_5	1403819.BATR01000059_gene1822	2.922e-55	196.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
DTH3_k127_5393657_7	278957.ABEA03000086_gene2506	8.742e-37	141.0	COG4576@1|root,COG4576@2|Bacteria,46VMK@74201|Verrucomicrobia,3K8BF@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
DTH3_k127_5393657_10	794903.OPIT5_04210	1.75e-28	125.0	COG4577@1|root,COG4577@2|Bacteria,46W1J@74201|Verrucomicrobia,3K8AE@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
DTH3_k127_5393657_1	794903.OPIT5_04205	9.17e-150	487.0	COG0282@1|root,COG0282@2|Bacteria,46TZF@74201|Verrucomicrobia,3K7U1@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
DTH3_k127_5393657_8	452637.Oter_1291	1.939e-35	137.0	COG4577@1|root,COG4577@2|Bacteria,46WBA@74201|Verrucomicrobia,3K89K@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
DTH3_k127_5393657_9	794903.OPIT5_04195	2.659e-33	130.0	COG4577@1|root,COG4577@2|Bacteria,46W7U@74201|Verrucomicrobia,3K8C2@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
DTH3_k127_5393657_3	278957.ABEA03000087_gene601	2.807e-101	343.0	COG4869@1|root,COG4869@2|Bacteria,46UMP@74201|Verrucomicrobia,3K7FS@414999|Opitutae	414999|Opitutae	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
DTH3_k127_5393657_6	314230.DSM3645_04975	5.865e-50	188.0	COG1349@1|root,COG1349@2|Bacteria,2IYW0@203682|Planctomycetes	203682|Planctomycetes	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
DTH3_k127_5393657_2	886293.Sinac_2714	1.646e-133	441.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_5393657_4	240016.ABIZ01000001_gene272	8.412e-64	230.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
DTH3_k127_5393657_12	794903.OPIT5_29490	3.284e-16	87.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5395949_0	497964.CfE428DRAFT_1388	9.981e-67	232.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_5395949_3	497964.CfE428DRAFT_1390	8.943e-20	94.0	2ET1N@1|root,33KJT@2|Bacteria,46TA1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5395949_1	411490.ANACAC_03351	4.425e-47	183.0	COG0371@1|root,COG0371@2|Bacteria,1V994@1239|Firmicutes	1239|Firmicutes	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
DTH3_k127_5402314_0	497964.CfE428DRAFT_1447	0.0	1158.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
DTH3_k127_5402314_1	1437425.CSEC_1907	0.0002839	44.0	COG1077@1|root,COG1077@2|Bacteria,2JFNV@204428|Chlamydiae	204428|Chlamydiae	D	shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DTH3_k127_5402675_2	1156937.MFUM_940009	1.35e-32	132.0	COG0839@1|root,COG0839@2|Bacteria,46T5P@74201|Verrucomicrobia,37GUV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH3_k127_5402675_1	794903.OPIT5_18130	3.791e-49	179.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
DTH3_k127_5402675_3	1156937.MFUM_940008	1.091e-31	127.0	COG0713@1|root,COG0713@2|Bacteria,46SX4@74201|Verrucomicrobia,37GV9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH3_k127_5402675_0	1156937.MFUM_940007	8.082e-116	381.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,37GBS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH3_k127_5404262_0	1123242.JH636436_gene130	4.207e-165	537.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DTH3_k127_5404262_1	1123508.JH636439_gene1318	5.881e-63	233.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
DTH3_k127_5404262_2	1125863.JAFN01000001_gene2967	1.562e-36	143.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
DTH3_k127_5404262_3	745411.B3C1_05932	0.0002703	51.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1J9VA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein	xpsH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
DTH3_k127_5409068_4	583355.Caka_2769	1.816e-62	220.0	COG0635@1|root,COG0635@2|Bacteria,46TQX@74201|Verrucomicrobia,3K7DD@414999|Opitutae	414999|Opitutae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
DTH3_k127_5409068_6	391625.PPSIR1_12288	1.195e-07	60.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
DTH3_k127_5409068_3	1379270.AUXF01000005_gene406	3.627e-112	379.0	COG1232@1|root,COG1232@2|Bacteria,1ZUZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
DTH3_k127_5409068_2	382464.ABSI01000005_gene1230	5.108e-117	385.0	COG0276@1|root,COG0276@2|Bacteria,46XCA@74201|Verrucomicrobia,2IVEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ferrochelatase	-	-	-	-	-	-	-	-	-	-	-	-	Ferrochelatase
DTH3_k127_5409068_1	1550073.JROH01000032_gene1995	1.695e-122	408.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,2K21U@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
DTH3_k127_5409068_7	1123070.KB899250_gene635	0.0006183	48.0	COG1918@1|root,COG1918@2|Bacteria,46ZGK@74201|Verrucomicrobia,2IWG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
DTH3_k127_5409068_0	742725.HMPREF9450_01261	5.9e-135	446.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,4PAMG@976|Bacteroidetes,2FXAJ@200643|Bacteroidia	976|Bacteroidetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
DTH3_k127_5409068_5	794903.OPIT5_19770	2.364e-37	144.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
DTH3_k127_5428163_0	497965.Cyan7822_3036	8.824e-153	497.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,3KH4V@43988|Cyanothece	1117|Cyanobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
DTH3_k127_5428163_1	349966.DJ58_4193	2.007e-135	445.0	COG4097@1|root,COG4097@2|Bacteria,1MV9P@1224|Proteobacteria,1SXIQ@1236|Gammaproteobacteria,41HAT@629|Yersinia	1236|Gammaproteobacteria	P	FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
DTH3_k127_5431720_0	497964.CfE428DRAFT_4863	1.24e-70	251.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5431720_1	794903.OPIT5_05960	8.966e-14	73.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_5451006_3	1195236.CTER_2031	2.918e-53	194.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24G9G@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH3_k127_5451006_1	1396418.BATQ01000003_gene1355	5.513e-133	438.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH3_k127_5451006_2	530564.Psta_4484	9.995e-126	416.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_5451006_5	530564.Psta_1454	1.935e-14	74.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH3_k127_5451006_4	313612.L8106_06989	1.022e-19	94.0	COG2337@1|root,COG2337@2|Bacteria,1G72T@1117|Cyanobacteria,1HDXS@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DTH3_k127_5451006_0	530564.Psta_1454	1.082e-137	441.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH3_k127_5455809_1	497964.CfE428DRAFT_0775	4.515e-80	273.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH3_k127_5455809_0	497964.CfE428DRAFT_0777	1.335e-178	585.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
DTH3_k127_5455809_2	497964.CfE428DRAFT_0779	1.013e-48	188.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Apolipoprotein
DTH3_k127_5459958_4	1499967.BAYZ01000137_gene111	8.086e-14	74.0	2FGP7@1|root,348IT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5459958_0	886293.Sinac_7347	1.731e-146	477.0	COG3507@1|root,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5459958_3	552398.HMPREF0866_03064	1.319e-21	98.0	2ED8C@1|root,3374X@2|Bacteria,1W0C5@1239|Firmicutes,24S5N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Smr
DTH3_k127_5459958_2	497964.CfE428DRAFT_0420	4.134e-39	152.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5459958_1	1382356.JQMP01000003_gene2064	5.078e-51	193.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
DTH3_k127_5462470_3	1043205.AFYF01000030_gene487	2.301e-05	57.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2I2T4@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_2,PQQ_2
DTH3_k127_5462470_4	1236976.JCM16418_4253	0.0001219	55.0	COG1409@1|root,COG2041@1|root,COG3211@1|root,COG4733@1|root,COG1409@2|Bacteria,COG2041@2|Bacteria,COG3211@2|Bacteria,COG4733@2|Bacteria,1V7PQ@1239|Firmicutes,4IUC5@91061|Bacilli,277JF@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,SLH,fn3
DTH3_k127_5462470_1	1396141.BATP01000042_gene1928	2.679e-41	171.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_5462470_0	1396141.BATP01000042_gene1927	4.413e-101	370.0	COG1520@1|root,COG4625@1|root,COG5295@1|root,COG1520@2|Bacteria,COG4625@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DTH3_k127_5471569_2	314230.DSM3645_04115	7.34e-93	311.0	COG1073@1|root,COG1073@2|Bacteria,2IYBP@203682|Planctomycetes	203682|Planctomycetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
DTH3_k127_5471569_1	521674.Plim_0111	5.092e-133	438.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_5471569_0	1403819.BATR01000057_gene1772	4.148e-251	809.0	COG3474@1|root,COG3474@2|Bacteria,46TEP@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_5471569_4	497964.CfE428DRAFT_6108	0.0005239	52.0	2FCZ3@1|root,3451R@2|Bacteria,46WBW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH3_k127_5471569_3	1124982.MSI_15100	1.692e-06	58.0	COG2834@1|root,COG2834@2|Bacteria,2J5AT@203691|Spirochaetes	203691|Spirochaetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
DTH3_k127_5476323_0	452637.Oter_0135	1.254e-306	953.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
DTH3_k127_5476323_11	1125700.HMPREF9195_01844	2.118e-06	58.0	2AIAW@1|root,318RT@2|Bacteria,2J6NU@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5476323_10	742159.HMPREF0004_3321	5.768e-09	64.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,2W0FN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
DTH3_k127_5476323_6	497964.CfE428DRAFT_3383	3.523e-40	156.0	COG0262@1|root,COG0262@2|Bacteria,46T19@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
DTH3_k127_5476323_2	1379698.RBG1_1C00001G0607	1.748e-91	338.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
DTH3_k127_5476323_5	1082933.MEA186_30762	9.312e-44	185.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43NVJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
DTH3_k127_5476323_7	243090.RB9985	5.352e-38	149.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5476323_13	1047013.AQSP01000089_gene1181	1.286e-05	48.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
DTH3_k127_5476323_4	760192.Halhy_1187	2.441e-62	223.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,1IYJE@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
DTH3_k127_5476323_3	525904.Tter_2139	7.8e-67	239.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH3_k127_5476323_1	525904.Tter_2133	6.375e-128	419.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
DTH3_k127_5476323_8	1163409.UUA_06087	3.802e-21	104.0	COG0697@1|root,COG0697@2|Bacteria,1PXBY@1224|Proteobacteria,1TCXJ@1236|Gammaproteobacteria,1X9UW@135614|Xanthomonadales	135614|Xanthomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DTH3_k127_5476323_9	1457250.BBMO01000003_gene3175	1.167e-11	72.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0NY@28890|Euryarchaeota,23Y3K@183963|Halobacteria	183963|Halobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DTH3_k127_5484736_2	478741.JAFS01000001_gene2028	2.62e-15	78.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH3_k127_5484736_0	1267535.KB906767_gene1032	1.311e-97	332.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DTH3_k127_5484736_4	1396141.BATP01000057_gene3046	6.21e-05	48.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5484736_1	386456.JQKN01000023_gene72	1.177e-76	265.0	arCOG01778@1|root,arCOG01778@2157|Archaea,2XU6W@28890|Euryarchaeota	28890|Euryarchaeota	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
DTH3_k127_5486669_0	595460.RRSWK_04184	1.42e-149	493.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
DTH3_k127_5490904_1	497964.CfE428DRAFT_3579	3.202e-150	482.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_5490904_0	1123070.KB899248_gene60	9.902e-189	595.0	COG0017@1|root,COG0017@2|Bacteria,46TN6@74201|Verrucomicrobia,2ITHF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH3_k127_5501377_0	497964.CfE428DRAFT_1254	3.521e-225	706.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
DTH3_k127_5501377_1	497964.CfE428DRAFT_2502	7.757e-78	276.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DTH3_k127_5508197_5	288000.BBta_1040	8.105e-15	75.0	COG3693@1|root,COG3693@2|Bacteria,1QXZM@1224|Proteobacteria,2TXEV@28211|Alphaproteobacteria,3K6U7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
DTH3_k127_5508197_4	313590.MED134_04514	9.309e-16	90.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,37EHK@326319|Dokdonia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH3_k127_5508197_2	32057.KB217478_gene7545	1.715e-65	240.0	COG2730@1|root,COG2730@2|Bacteria,1G3EZ@1117|Cyanobacteria	1117|Cyanobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
DTH3_k127_5508197_0	861299.J421_5653	1.348e-126	421.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_5508197_1	1267535.KB906767_gene3448	1.474e-73	262.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Pectate_lyase_3
DTH3_k127_5508197_3	1122611.KB903963_gene4742	6.56e-37	152.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria,4EGCR@85012|Streptosporangiales	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
DTH3_k127_5508197_6	1121875.KB907549_gene1764	0.0005206	47.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	inlA	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DUF285,LRR_4,LRR_6,Lectin_legB,Strep_his_triad
DTH3_k127_5513328_0	1125863.JAFN01000001_gene1869	8.787e-164	540.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DTH3_k127_5553599_5	357808.RoseRS_1901	1.851e-19	88.0	2BHS9@1|root,32BVT@2|Bacteria,2GBBD@200795|Chloroflexi,377P4@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
DTH3_k127_5553599_1	272624.lpg0358	4.046e-89	301.0	COG0623@1|root,COG0623@2|Bacteria,1N64Z@1224|Proteobacteria,1T3N8@1236|Gammaproteobacteria,1JC7V@118969|Legionellales	118969|Legionellales	I	KR domain	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH3_k127_5553599_2	344747.PM8797T_12848	4.638e-61	220.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH3_k127_5553599_3	272624.lpg0359	2.637e-41	159.0	COG0236@1|root,COG0236@2|Bacteria,1NM9E@1224|Proteobacteria,1SINP@1236|Gammaproteobacteria,1JEJN@118969|Legionellales	118969|Legionellales	IQ	Phosphopantetheine attachment site	acpP_2	-	-	-	-	-	-	-	-	-	-	-	PP-binding
DTH3_k127_5553599_4	1122164.JHWF01000017_gene537	1.003e-20	102.0	COG0764@1|root,COG0764@2|Bacteria,1PCKD@1224|Proteobacteria,1SXNH@1236|Gammaproteobacteria,1JDAD@118969|Legionellales	118969|Legionellales	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
DTH3_k127_5553599_0	272624.lpg0361	1.873e-142	465.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JDCZ@118969|Legionellales	118969|Legionellales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH3_k127_5553599_6	340.xcc-b100_3338	7.871e-05	53.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3AN@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH3_k127_555872_0	1416760.AYMS01000107_gene88	1.739e-45	182.0	COG3385@1|root,COG3385@2|Bacteria,4NXT2@976|Bacteroidetes	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
DTH3_k127_555872_1	41431.PCC8801_2105	8.272e-38	158.0	28N1B@1|root,2ZB7I@2|Bacteria,1G011@1117|Cyanobacteria,3KH8M@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5563951_0	861299.J421_1753	1.508e-250	812.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH3_k127_5563951_1	290512.Paes_2385	8.871e-54	198.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DTH3_k127_5563951_2	1121918.ARWE01000001_gene1451	1.236e-35	149.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DTH3_k127_5568572_2	1296990.H845_1493	8.49e-17	89.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,2UB4D@28211|Alphaproteobacteria,2JWYI@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DTH3_k127_5568572_0	497964.CfE428DRAFT_5778	2.054e-105	352.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
DTH3_k127_5568572_1	247639.MGP2080_02111	7.062e-29	124.0	COG2067@1|root,COG2067@2|Bacteria,1NDQA@1224|Proteobacteria,1TIWZ@1236|Gammaproteobacteria,1JBA2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5588470_1	639282.DEFDS_0915	2.312e-15	76.0	COG1838@1|root,COG1838@2|Bacteria,2GF6R@200930|Deferribacteres	200930|Deferribacteres	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
DTH3_k127_5588470_0	478741.JAFS01000002_gene564	1.957e-166	533.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,37GDA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DTH3_k127_5588470_2	1396141.BATP01000060_gene4559	1.139e-13	76.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
DTH3_k127_5596390_3	536227.CcarbDRAFT_0305	0.0001171	48.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes	1239|Firmicutes	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
DTH3_k127_5596390_2	1541065.JRFE01000058_gene5541	5.331e-22	104.0	2DBIE@1|root,32ZYG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5596390_1	518766.Rmar_1438	4.688e-136	465.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1438|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5596390_0	518766.Rmar_1439	1.143e-235	749.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1439|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5630514_1	604331.AUHY01000019_gene1835	2.062e-29	118.0	COG0509@1|root,COG0509@2|Bacteria,1WJYK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DTH3_k127_5630514_0	234267.Acid_2132	6.61e-105	347.0	COG1028@1|root,COG1028@2|Bacteria,3Y7BE@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH3_k127_5630514_2	1242864.D187_001577	1.977e-05	57.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria	1224|Proteobacteria	P	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH3_k127_5633628_2	521674.Plim_4045	4.23e-32	147.0	2CGJ6@1|root,31UKG@2|Bacteria,2J1GT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5633628_0	1396418.BATQ01000046_gene6147	1.68e-93	316.0	COG1082@1|root,COG1082@2|Bacteria,46WKR@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_5633628_1	497964.CfE428DRAFT_4653	3.24e-65	231.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	SMART helicase c2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
DTH3_k127_5637532_1	1121887.AUDK01000010_gene1434	1.403e-05	53.0	2DP52@1|root,330JK@2|Bacteria,4NUTX@976|Bacteroidetes,1I5F0@117743|Flavobacteriia,2NWA6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_564310_0	671143.DAMO_0532	0.0	1347.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DTH3_k127_564310_1	316274.Haur_0141	4.671e-17	82.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi,375VM@32061|Chloroflexia	32061|Chloroflexia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DTH3_k127_5652962_0	1123073.KB899241_gene3242	7.497e-36	158.0	COG1572@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria,1SUAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5655271_4	478741.JAFS01000002_gene857	6.846e-11	66.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia,37GAG@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
DTH3_k127_5655271_1	224325.AF_2211	4.204e-50	185.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
DTH3_k127_5655271_2	497964.CfE428DRAFT_5353	1.026e-35	151.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH3_k127_5655271_3	1219084.AP014508_gene1338	2.151e-13	82.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DTH3_k127_5655271_0	926560.KE387023_gene1701	1.426e-196	637.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH3_k127_5655545_0	530564.Psta_1209	6.628e-217	696.0	COG0003@1|root,COG0003@2|Bacteria,2IY37@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM arsenite-activated ATPase (arsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
DTH3_k127_5655545_6	794903.OPIT5_07895	2.691e-16	80.0	COG2331@1|root,COG2331@2|Bacteria,46ZFV@74201|Verrucomicrobia,3K8G5@414999|Opitutae	414999|Opitutae	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5655545_8	1112216.JH594425_gene2614	0.0001643	51.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG4566@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG4566@2|Bacteria,1NRP8@1224|Proteobacteria,2TWP9@28211|Alphaproteobacteria,2KETS@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GerE,HATPase_c,HisKA,PAS_10,Response_reg
DTH3_k127_5655545_4	1156937.MFUM_270017	5.351e-30	132.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,37GID@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
DTH3_k127_5655545_1	478741.JAFS01000001_gene1976	5.099e-147	477.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
DTH3_k127_5655545_7	1283300.ATXB01000001_gene1577	1.269e-15	79.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH3_k127_5655545_3	1283300.ATXB01000001_gene1577	4.532e-44	167.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH3_k127_5655545_2	521011.Mpal_2572	7.831e-67	235.0	COG4063@1|root,arCOG03221@2157|Archaea	2157|Archaea	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA-2	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
DTH3_k127_5655545_9	2903.EOD19594	0.0005274	48.0	296NR@1|root,2RDMV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817,Peptidase_M14
DTH3_k127_5663819_1	1123070.KB899248_gene194	1.536e-134	436.0	COG1524@1|root,COG1524@2|Bacteria,46UZ5@74201|Verrucomicrobia,2ITHB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH3_k127_5663819_2	221288.JH992901_gene3829	3.146e-124	412.0	COG0337@1|root,COG0337@2|Bacteria,1G2JF@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM 3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH3_k127_5663819_0	886293.Sinac_6122	1.948e-141	461.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
DTH3_k127_5673700_0	251221.35213566	9.372e-68	256.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5673700_1	1125863.JAFN01000001_gene3036	1.847e-39	160.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
DTH3_k127_5675960_1	1210884.HG799464_gene10599	1.194e-52	194.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	VP0394	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DTH3_k127_5675960_2	1294143.H681_01225	1.167e-21	96.0	COG0863@1|root,COG0863@2|Bacteria,1PNW2@1224|Proteobacteria,1SEG5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
DTH3_k127_5675960_0	1229780.BN381_640005	5.488e-101	354.0	29GCA@1|root,303A5@2|Bacteria,2H1W0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5681072_0	1379698.RBG1_1C00001G1671	1.491e-198	649.0	COG1228@1|root,COG1228@2|Bacteria,2NPD9@2323|unclassified Bacteria	2|Bacteria	Q	Amidohydrolase family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DTH3_k127_5681072_1	1183438.GKIL_2152	1.395e-97	335.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DTH3_k127_5681072_2	1329516.JPST01000001_gene934	1.826e-30	120.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4HBUQ@91061|Bacilli,27B1T@186824|Thermoactinomycetaceae	91061|Bacilli	E	Thermophilic metalloprotease (M29)	ampS5	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
DTH3_k127_5683398_1	240016.ABIZ01000001_gene3006	2.702e-37	144.0	COG0861@1|root,COG0861@2|Bacteria,46W6F@74201|Verrucomicrobia,2IVJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
DTH3_k127_5683398_0	452637.Oter_3464	7.221e-176	581.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
DTH3_k127_5683398_2	481448.Minf_1937	1.267e-15	79.0	COG1862@1|root,COG1862@2|Bacteria,46T88@74201|Verrucomicrobia,37GU3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
DTH3_k127_5686435_0	344747.PM8797T_11556	9.605e-121	402.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_5686435_2	1123242.JH636434_gene5340	2.566e-76	280.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_5686435_3	1047013.AQSP01000114_gene693	6.43e-28	119.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5686435_1	497964.CfE428DRAFT_3356	3.759e-117	396.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,46TMH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
DTH3_k127_5686435_4	382464.ABSI01000011_gene3041	1.261e-19	89.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia,2ITMZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DTH3_k127_5691444_0	481448.Minf_1203	6.938e-137	439.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,37FVD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DTH3_k127_5691444_2	1121430.JMLG01000021_gene1382	2.866e-56	208.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
DTH3_k127_5691444_1	497964.CfE428DRAFT_2138	3.525e-90	310.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia	74201|Verrucomicrobia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
DTH3_k127_5698332_0	697284.ERIC2_c41250	3.58e-125	417.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,26RSI@186822|Paenibacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
DTH3_k127_5698332_1	1396418.BATQ01000049_gene368	2.367e-76	265.0	COG2103@1|root,COG2971@1|root,COG2103@2|Bacteria,COG2971@2|Bacteria,46SJI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,SIS_2
DTH3_k127_570261_0	278963.ATWD01000001_gene3347	2.962e-63	235.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
DTH3_k127_570261_1	743299.Acife_0301	3.306e-55	208.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RMRA@1236|Gammaproteobacteria,2NDFW@225057|Acidithiobacillales	225057|Acidithiobacillales	L	DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
DTH3_k127_5703020_0	794903.OPIT5_30520	2.588e-239	763.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5703020_1	530564.Psta_1928	7.974e-77	286.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_5710395_0	1396141.BATP01000003_gene5168	6.635e-133	426.0	2EKQJ@1|root,33EEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5710395_1	1235803.C825_02071	1.219e-54	205.0	COG3250@1|root,COG3250@2|Bacteria,4NEP8@976|Bacteroidetes,2FMRW@200643|Bacteroidia,22ZAN@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH3_k127_5713247_13	1267534.KB906754_gene3779	1.779e-12	67.0	COG0852@1|root,COG0852@2|Bacteria,3Y72R@57723|Acidobacteria,2JM53@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH3_k127_5713247_1	1267534.KB906754_gene3778	7.847e-198	622.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DTH3_k127_5713247_5	1216966.BAUC01000035_gene3110	3.608e-104	358.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Glutamate synthase	gltD	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_3503,iYL1228.KPN_03625	Fer4_20,Pyr_redox_2
DTH3_k127_5713247_8	452637.Oter_0743	9.92e-52	186.0	COG0838@1|root,COG0838@2|Bacteria,46XVA@74201|Verrucomicrobia,3K8I9@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DTH3_k127_5713247_6	452637.Oter_0744	5.931e-90	298.0	COG0377@1|root,COG0377@2|Bacteria,46YVB@74201|Verrucomicrobia,3K85T@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DTH3_k127_5713247_7	452637.Oter_0745	1.857e-58	208.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DTH3_k127_5713247_2	452637.Oter_0746	7.986e-190	598.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K8K5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DTH3_k127_5713247_3	452637.Oter_0747	1.24e-152	488.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K82N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH3_k127_5713247_9	452637.Oter_0748	1.044e-50	194.0	COG1143@1|root,COG1143@2|Bacteria,46YB4@74201|Verrucomicrobia,3K98S@414999|Opitutae	414999|Opitutae	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
DTH3_k127_5713247_10	452637.Oter_0749	6.71e-43	163.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH3_k127_5713247_11	452637.Oter_0750	1.802e-36	141.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH3_k127_5713247_0	452637.Oter_0751	9.609e-237	741.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH3_k127_5713247_12	1121413.JMKT01000008_gene1370	2.525e-25	114.0	2BR4E@1|root,32K2C@2|Bacteria,1Q2KP@1224|Proteobacteria,42X9C@68525|delta/epsilon subdivisions,2WSUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5713247_4	452637.Oter_0753	1.544e-137	444.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	2|Bacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ndhD5	-	1.6.5.3	ko:K05568,ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2	-	iJN678.ndhD	Proton_antipo_M
DTH3_k127_5730575_1	886293.Sinac_0920	1.385e-19	93.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_5730575_3	1463879.JOHP01000017_gene2377	3.635e-10	70.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria	201174|Actinobacteria	K	Arac family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
DTH3_k127_5730575_0	1396141.BATP01000003_gene4864	1.411e-38	168.0	COG2273@1|root,COG3210@1|root,COG3533@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG5295@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5295@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	2|Bacteria	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	oprH	-	3.2.1.4,3.2.1.73	ko:K01179,ko:K01216,ko:K02014,ko:K07004,ko:K15125,ko:K16087,ko:K21449	ko00500,ko01100,ko05133,map00500,map01100,map05133	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko02000	1.B.14,1.B.14.2,1.B.40.2	GH5,GH9	-	Glyco_hydro_16,HemolysinCabind,OMP_b-brl,fn3
DTH3_k127_5730575_2	521674.Plim_3825	7.577e-17	89.0	COG2165@1|root,COG2165@2|Bacteria,2J2TU@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_57371_3	886293.Sinac_4894	5.907e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_57371_2	886293.Sinac_4894	2.064e-32	140.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_57371_1	886293.Sinac_4894	1.038e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_57371_0	344747.PM8797T_32395	3.065e-114	389.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
DTH3_k127_57371_4	547042.BACCOPRO_00511	8.775e-17	91.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,2FR8R@200643|Bacteroidia,4AQA2@815|Bacteroidaceae	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DTH3_k127_5767900_0	1396418.BATQ01000056_gene181	1.042e-94	317.0	COG4188@1|root,COG4188@2|Bacteria,46TTD@74201|Verrucomicrobia,2IVPV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
DTH3_k127_5767900_1	329726.AM1_4632	7.937e-57	209.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
DTH3_k127_5767900_2	768670.Calni_0018	0.0005322	49.0	COG0296@1|root,COG0296@2|Bacteria,2GFUK@200930|Deferribacteres	200930|Deferribacteres	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
DTH3_k127_5772850_0	864702.OsccyDRAFT_0858	4.44e-103	338.0	COG0579@1|root,COG0579@2|Bacteria,1G0XV@1117|Cyanobacteria,1H77Y@1150|Oscillatoriales	1117|Cyanobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
DTH3_k127_5772850_1	1396141.BATP01000036_gene3853	1.558e-52	194.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia,2ITYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
DTH3_k127_5772850_2	1172185.KB911516_gene2443	1.759e-10	63.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4FV17@85025|Nocardiaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_5791163_0	208439.AJAP_24615	2.272e-144	494.0	COG1361@1|root,COG4935@1|root,COG1361@2|Bacteria,COG4935@2|Bacteria,2I2W6@201174|Actinobacteria,4EDRS@85010|Pseudonocardiales	201174|Actinobacteria	MO	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
DTH3_k127_5797393_0	234267.Acid_1327	7.485e-80	283.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DTH3_k127_5797393_1	234267.Acid_1327	1.184e-69	261.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DTH3_k127_5797393_2	742817.HMPREF9449_01242	1.265e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22XN2@171551|Porphyromonadaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
DTH3_k127_5797393_3	1122973.KB904281_gene1071	2.321e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,22X3E@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD
DTH3_k127_5803398_1	240016.ABIZ01000001_gene4111	4.284e-11	64.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DTH3_k127_5803398_2	1303518.CCALI_02658	1.44e-10	71.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_5803398_0	1303518.CCALI_00581	1.655e-142	470.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	ywjF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Nitrate_red_gam
DTH3_k127_580964_2	937777.Deipe_0638	7.484e-14	86.0	COG1649@1|root,COG1649@2|Bacteria,1WM1V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
DTH3_k127_580964_1	1121920.AUAU01000009_gene1881	1.411e-54	218.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH3_k127_580964_0	1122605.KB893625_gene1943	1.983e-95	325.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1IUUU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH3_k127_5809845_2	519989.ECTPHS_02009	1.655e-44	169.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DTH3_k127_5809845_0	1123242.JH636435_gene1092	3.242e-179	571.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_5809845_3	278957.ABEA03000093_gene4635	7.387e-20	94.0	arCOG03330@1|root,2Z82Q@2|Bacteria	2|Bacteria	S	PFAM Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
DTH3_k127_5809845_1	234267.Acid_6968	6.515e-48	175.0	COG5012@1|root,COG5012@2|Bacteria,3Y88D@57723|Acidobacteria	57723|Acidobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
DTH3_k127_5811387_0	583355.Caka_1736	2.821e-73	276.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_5812613_1	1121920.AUAU01000024_gene2375	9.745e-12	74.0	COG3303@1|root,COG3303@2|Bacteria,3Y8US@57723|Acidobacteria	57723|Acidobacteria	P	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH3_k127_5812613_0	1158338.JNLJ01000001_gene940	1.494e-46	175.0	COG3391@1|root,COG3391@2|Bacteria,2G4DB@200783|Aquificae	200783|Aquificae	S	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL
DTH3_k127_5818130_0	880070.Cycma_2352	1.056e-40	171.0	COG3669@1|root,COG3669@2|Bacteria,4NHRG@976|Bacteroidetes,47TRP@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
DTH3_k127_5818130_1	1121904.ARBP01000052_gene3650	7.599e-28	126.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Hydrolase_4
DTH3_k127_5818130_2	935948.KE386493_gene2375	1.08e-06	58.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5820263_0	1501230.ET33_33510	6.972e-90	308.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HACU@91061|Bacilli,26SWK@186822|Paenibacillaceae	91061|Bacilli	G	1,3--beta-D-glucan 3-glucanohydrolase	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CBM_4_9,Glyco_hydro_16,RicinB_lectin_2
DTH3_k127_582282_1	1396141.BATP01000056_gene3264	3.065e-83	282.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,2IUI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_582282_0	794903.OPIT5_29540	3.353e-106	359.0	COG4585@1|root,COG4585@2|Bacteria,46TVJ@74201|Verrucomicrobia,3K9CA@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
DTH3_k127_582282_3	1267534.KB906754_gene3064	4.853e-06	51.0	2EFZF@1|root,339RM@2|Bacteria,3Y5X5@57723|Acidobacteria,2JK63@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_582282_2	324925.Ppha_2361	4.34e-16	81.0	2E35S@1|root,32Y5P@2|Bacteria	2|Bacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
DTH3_k127_5823733_2	1038859.AXAU01000001_gene3812	6.984e-70	243.0	COG0702@1|root,COG0702@2|Bacteria,1Q5QN@1224|Proteobacteria,2U3R1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
DTH3_k127_5823733_1	640511.BC1002_6686	1.029e-70	248.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5823733_0	319003.Bra1253DRAFT_01013	1.678e-150	488.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,3JQXY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate	-	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
DTH3_k127_5843473_11	1396141.BATP01000034_gene4147	9.334e-33	137.0	COG3189@1|root,COG3189@2|Bacteria,46VV6@74201|Verrucomicrobia,2IWA9@203494|Verrucomicrobiae	2|Bacteria	S	Protein of unknown function, DUF488	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
DTH3_k127_5843473_1	525904.Tter_0327	2.381e-280	880.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
DTH3_k127_5843473_15	1207075.PputUW4_04220	0.0001286	52.0	COG3708@1|root,COG3708@2|Bacteria,1NBPE@1224|Proteobacteria,1SFP2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
DTH3_k127_5843473_6	323261.Noc_2734	1.511e-118	393.0	COG1449@1|root,COG1449@2|Bacteria,1R5KI@1224|Proteobacteria,1S0ID@1236|Gammaproteobacteria,1WXJ4@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
DTH3_k127_5843473_3	472759.Nhal_0095	5.016e-231	724.0	COG0297@1|root,COG0297@2|Bacteria,1P7F2@1224|Proteobacteria,1RZVJ@1236|Gammaproteobacteria,1WX4C@135613|Chromatiales	135613|Chromatiales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
DTH3_k127_5843473_4	1283300.ATXB01000001_gene664	5.201e-169	540.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1XFWC@135618|Methylococcales	135618|Methylococcales	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	hDGE_amylase
DTH3_k127_5843473_2	243233.MCA2119	4.045e-257	799.0	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1XG1U@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
DTH3_k127_5843473_10	1384056.N787_02850	1.058e-52	201.0	2F24D@1|root,33V2Z@2|Bacteria,1NV0Y@1224|Proteobacteria,1SN7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5843473_7	269799.Gmet_1782	3.036e-89	301.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
DTH3_k127_5843473_9	257314.LJ_0003	1.423e-61	226.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
DTH3_k127_5843473_5	452637.Oter_2109	1.136e-166	532.0	COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,3K7UW@414999|Opitutae	414999|Opitutae	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DTH3_k127_5843473_14	867845.KI911784_gene1416	1.39e-05	54.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
DTH3_k127_5843473_13	278957.ABEA03000041_gene2093	1.242e-19	100.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
DTH3_k127_5843473_8	1499967.BAYZ01000095_gene4228	1.499e-73	255.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
DTH3_k127_5843473_0	1396141.BATP01000032_gene4423	2.244e-283	889.0	COG5297@1|root,COG5297@2|Bacteria,46UD4@74201|Verrucomicrobia,2IVIH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5843473_12	880073.Calab_0272	1.474e-27	125.0	COG1649@1|root,COG3023@1|root,COG3391@1|root,COG4412@1|root,COG1649@2|Bacteria,COG3023@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.20,3.4.17.22,3.5.1.28	ko:K01187,ko:K01448,ko:K07752	ko00052,ko00500,ko01100,ko01503,map00052,map00500,map01100,map01503	M00727	R00028,R00801,R00802,R04112,R06087,R06088	RC00028,RC00049,RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	GH31	-	Amidase_2
DTH3_k127_5846656_2	348824.LPU83_1952	3.76e-62	219.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TRE4@28211|Alphaproteobacteria,4BG5P@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
DTH3_k127_5846656_0	521674.Plim_0789	0.0	1000.0	COG3119@1|root,COG3119@2|Bacteria,2IXNZ@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
DTH3_k127_5846656_1	1297570.MESS4_670033	1.358e-87	292.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,43K0Q@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH3_k127_5867498_1	478741.JAFS01000002_gene596	4.284e-95	319.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,37G7B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH3_k127_5867498_0	497964.CfE428DRAFT_5386	1.46e-128	420.0	COG2876@1|root,COG2876@2|Bacteria,46SUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
DTH3_k127_5867498_2	497964.CfE428DRAFT_0260	1.598e-45	168.0	COG0822@1|root,COG0822@2|Bacteria,46VAC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
DTH3_k127_58793_1	1499967.BAYZ01000089_gene5014	9.585e-138	457.0	COG0043@1|root,COG0043@2|Bacteria	2|Bacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH3_k127_58793_4	265072.Mfla_2506	9.218e-47	188.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KMRM@206350|Nitrosomonadales	206350|Nitrosomonadales	FG	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
DTH3_k127_58793_3	1499967.BAYZ01000089_gene5015	3.356e-82	280.0	COG1212@1|root,COG1212@2|Bacteria,2NP8R@2323|unclassified Bacteria	2|Bacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DTH3_k127_58793_2	1123242.JH636434_gene4153	3.357e-113	377.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_58793_0	1499967.BAYZ01000095_gene4068	1.015e-156	501.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_5901175_0	335543.Sfum_3489	8.851e-87	305.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,1QU25@1224|Proteobacteria,42YRH@68525|delta/epsilon subdivisions,2WUGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
DTH3_k127_5903896_2	1089553.Tph_c24830	2.089e-13	71.0	COG0845@1|root,COG0845@2|Bacteria,1V0ZP@1239|Firmicutes,24D7U@186801|Clostridia,42GIU@68295|Thermoanaerobacterales	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH3_k127_5903896_3	2423.NA23_0209590	0.0002641	51.0	COG1413@1|root,COG1413@2|Bacteria,2GDN4@200918|Thermotogae	200918|Thermotogae	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
DTH3_k127_5903896_0	1379270.AUXF01000004_gene3002	1.471e-109	374.0	COG2986@1|root,COG2986@2|Bacteria,1ZTEG@142182|Gemmatimonadetes	2|Bacteria	E	Aromatic amino acid lyase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009698,GO:0009699,GO:0009987,GO:0016043,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052883,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DTH3_k127_5903896_1	153721.MYP_192	9.957e-33	130.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DTH3_k127_5904030_1	1449063.JMLS01000009_gene2209	7.578e-135	456.0	28H6M@1|root,2Z7J0@2|Bacteria	2|Bacteria	G	Pectate lyase	pelY	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase_2
DTH3_k127_5904030_0	497964.CfE428DRAFT_4394	6.327e-214	671.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Beta_helix,F5_F8_type_C,Glyco_hydro_28,Melibiase_2,Pectate_lyase_3
DTH3_k127_5904030_2	1120999.JONM01000001_gene1189	1.666e-13	79.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Pectate_lyase_3
DTH3_k127_5911341_1	305700.B447_10758	0.0004922	51.0	2DU19@1|root,33NHC@2|Bacteria,1NKNM@1224|Proteobacteria,2VYQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5911341_0	211165.AJLN01000061_gene3942	6.58e-221	702.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,1JHUA@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
DTH3_k127_5915175_3	765913.ThidrDRAFT_1061	8.598e-36	149.0	COG2340@1|root,COG5549@1|root,COG2340@2|Bacteria,COG5549@2|Bacteria,1RJVF@1224|Proteobacteria,1SB6V@1236|Gammaproteobacteria,1X2BX@135613|Chromatiales	1236|Gammaproteobacteria	O	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	CAP,DUF4214
DTH3_k127_5915175_2	497964.CfE428DRAFT_5401	1.098e-81	289.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_5915175_1	497964.CfE428DRAFT_5401	4.265e-90	315.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_5915175_0	497964.CfE428DRAFT_5400	3.158e-92	311.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_5921131_0	1123073.KB899242_gene1369	1.893e-120	395.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,1X4B2@135614|Xanthomonadales	135614|Xanthomonadales	EM	Belongs to the DapA family	dapA2	-	3.5.4.22	ko:K21062	ko00330,map00330	-	R02280	RC00679	ko00000,ko00001,ko01000	-	-	-	DHDPS
DTH3_k127_5921131_2	1346791.M529_01465	3.319e-06	56.0	2CBBT@1|root,33166@2|Bacteria,1N354@1224|Proteobacteria,2USDI@28211|Alphaproteobacteria,2K9BJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5921131_1	497964.CfE428DRAFT_1990	3.113e-75	257.0	COG0665@1|root,COG0665@2|Bacteria,46TXP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
DTH3_k127_5928356_2	365046.Rta_17060	9.469e-11	72.0	COG4447@1|root,COG4447@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5928356_0	1403819.BATR01000184_gene6352	2.7e-92	309.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DTH3_k127_5928356_1	497964.CfE428DRAFT_4834	6.884e-24	108.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DTH3_k127_5930585_0	1396141.BATP01000060_gene4647	1.469e-142	485.0	COG0515@1|root,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
DTH3_k127_5930585_1	452637.Oter_2422	5.093e-62	219.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_5930585_2	886293.Sinac_6402	8.675e-29	128.0	2EJMI@1|root,33DCE@2|Bacteria,2J1MT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5936111_1	1110502.TMO_0647	3.855e-33	138.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VEVK@28211|Alphaproteobacteria,2JYN8@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
DTH3_k127_5936111_4	1121946.AUAX01000016_gene4757	0.0001707	53.0	COG2755@1|root,COG3266@1|root,COG2755@2|Bacteria,COG3266@2|Bacteria,2I2V4@201174|Actinobacteria,4D9Z9@85008|Micromonosporales	201174|Actinobacteria	E	Parallel beta-helix repeats	pelX	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_2,CBM_35,CBM_6
DTH3_k127_5936111_3	1123508.JH636446_gene6227	6.337e-06	57.0	COG2165@1|root,COG2165@2|Bacteria,2J1RN@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_5936111_2	1303518.CCALI_01258	2.262e-11	74.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_5936111_0	886293.Sinac_7036	1.122e-166	534.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5940589_1	886293.Sinac_7126	1.152e-114	380.0	COG1524@1|root,COG1524@2|Bacteria,2IYCV@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DTH3_k127_5940589_0	452637.Oter_0961	1.009e-144	468.0	COG1171@1|root,COG1171@2|Bacteria,46TW9@74201|Verrucomicrobia,3K73X@414999|Opitutae	414999|Opitutae	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
DTH3_k127_5940784_3	1449355.JQNR01000005_gene5972	7.082e-06	59.0	COG3055@1|root,COG4934@1|root,COG3055@2|Bacteria,COG4934@2|Bacteria,2IF2T@201174|Actinobacteria	201174|Actinobacteria	O	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1
DTH3_k127_5940784_1	1168059.KB899087_gene3167	6.892e-22	111.0	COG1409@1|root,COG2931@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3EZXC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM60,HemolysinCabind,Metallophos,PPC,Peptidase_M10_C
DTH3_k127_5940784_0	1121920.AUAU01000009_gene1881	1.444e-29	136.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH3_k127_5940784_2	935836.JAEL01000008_gene3952	1.577e-17	97.0	COG1524@1|root,COG5492@1|root,COG1524@2|Bacteria,COG5492@2|Bacteria,1V7WK@1239|Firmicutes,4IETN@91061|Bacilli,1ZEHY@1386|Bacillus	91061|Bacilli	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Laminin_G_3,Phosphodiest
DTH3_k127_59438_3	1499967.BAYZ01000068_gene1988	2.705e-05	47.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_59438_1	452637.Oter_4548	3.225e-48	174.0	COG1993@1|root,COG1993@2|Bacteria,46VZM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
DTH3_k127_59438_0	452637.Oter_4547	1.932e-49	179.0	COG0239@1|root,COG0239@2|Bacteria,46W5U@74201|Verrucomicrobia,3K8J7@414999|Opitutae	414999|Opitutae	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
DTH3_k127_59438_4	159087.Daro_0466	3.186e-05	46.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,2VVT0@28216|Betaproteobacteria,2KXPG@206389|Rhodocyclales	206389|Rhodocyclales	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
DTH3_k127_59438_2	1396141.BATP01000029_gene2250	9.194e-16	90.0	COG1525@1|root,COG1525@2|Bacteria,46WA1@74201|Verrucomicrobia,2IWGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5954976_0	1123242.JH636435_gene1594	1.196e-157	511.0	COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH3_k127_5954976_1	497964.CfE428DRAFT_1024	9.486e-40	152.0	2EBIG@1|root,335IZ@2|Bacteria,46WF8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5954976_2	1403819.BATR01000055_gene1733	1.912e-07	53.0	COG0583@1|root,COG0583@2|Bacteria,46V15@74201|Verrucomicrobia,2IUGE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
DTH3_k127_5963542_1	1123070.KB899247_gene1528	9.038e-34	150.0	COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
DTH3_k127_5963542_0	3880.AES83113	4.204e-163	526.0	COG0399@1|root,2S2DV@2759|Eukaryota,3816B@33090|Viridiplantae	33090|Viridiplantae	T	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DTH3_k127_5963542_2	306281.AJLK01000102_gene3405	1.051e-16	82.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5974135_2	344747.PM8797T_02169	1.748e-119	407.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
DTH3_k127_5974135_3	203275.BFO_2526	2.607e-44	164.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,2FTDQ@200643|Bacteroidia,22Z1W@171551|Porphyromonadaceae	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
DTH3_k127_5974135_1	700598.Niako_3627	2.805e-133	433.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,1IVNN@117747|Sphingobacteriia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
DTH3_k127_5974135_0	1121011.AUCB01000028_gene3056	1.404e-177	563.0	COG1554@1|root,COG1554@2|Bacteria,4NHVP@976|Bacteroidetes	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_5991351_0	497964.CfE428DRAFT_3889	1.216e-103	353.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DTH3_k127_5991351_1	497964.CfE428DRAFT_3890	1.072e-83	290.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DTH3_k127_5991351_2	404380.Gbem_3110	1.3e-07	53.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DTH3_k127_5997572_1	379066.GAU_0693	1.113e-38	151.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
DTH3_k127_5997572_0	1396418.BATQ01000025_gene5257	1.825e-41	161.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,2IUGA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
DTH3_k127_5997572_3	682795.AciX8_3725	4.946e-10	74.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
DTH3_k127_5997572_2	1396141.BATP01000034_gene4198	6.757e-19	103.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
DTH3_k127_5997572_4	8364.ENSXETP00000010179	6.515e-10	73.0	2CMMP@1|root,2QQVA@2759|Eukaryota,38DQG@33154|Opisthokonta,3BC84@33208|Metazoa,3CVS6@33213|Bilateria,487IG@7711|Chordata,48ZK4@7742|Vertebrata	33208|Metazoa	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH3_k127_5997572_5	1396141.BATP01000006_gene5432	0.0006272	53.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH3_k127_6010325_1	1123508.JH636449_gene7418	1.929e-145	477.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_6010325_0	1396418.BATQ01000099_gene5534	3.351e-170	552.0	COG2010@1|root,COG2010@2|Bacteria,46X91@74201|Verrucomicrobia,2IV25@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
DTH3_k127_6016938_0	756067.MicvaDRAFT_5451	4.9e-84	310.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
DTH3_k127_6016938_1	497964.CfE428DRAFT_3903	2.97e-38	150.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycoside hydrolase family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
DTH3_k127_6017077_6	794903.OPIT5_28075	1.995e-93	312.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,3K77F@414999|Opitutae	414999|Opitutae	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
DTH3_k127_6017077_4	497964.CfE428DRAFT_4273	6.93e-107	355.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
DTH3_k127_6017077_13	497964.CfE428DRAFT_4274	2.231e-32	130.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
DTH3_k127_6017077_11	278957.ABEA03000130_gene1706	1.215e-62	220.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH3_k127_6017077_5	278957.ABEA03000130_gene1703	8.509e-94	319.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
DTH3_k127_6017077_0	278957.ABEA03000130_gene1701	8.64e-241	754.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
DTH3_k127_6017077_16	278957.ABEA03000130_gene1699	8.648e-18	84.0	2EJWH@1|root,33DM6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2997
DTH3_k127_6017077_9	278957.ABEA03000130_gene1697	1.952e-83	288.0	COG0457@1|root,COG0457@2|Bacteria	278957.ABEA03000130_gene1697|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6017077_1	278957.ABEA03000130_gene1696	9.179e-146	478.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	2|Bacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH3_k127_6017077_8	497964.CfE428DRAFT_3544	7.406e-85	294.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia	74201|Verrucomicrobia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DTH3_k127_6017077_10	1192034.CAP_8072	3.761e-83	286.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2X5XK@28221|Deltaproteobacteria,2Z2YK@29|Myxococcales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	appB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
DTH3_k127_6017077_2	1403819.BATR01000065_gene1925	4.084e-143	477.0	COG4166@1|root,COG4166@2|Bacteria,46SBG@74201|Verrucomicrobia,2ITVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
DTH3_k127_6017077_17	278957.ABEA03000211_gene3535	1.148e-10	67.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,3K89V@414999|Opitutae	414999|Opitutae	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
DTH3_k127_6017077_7	452637.Oter_3825	2.035e-86	292.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,3K7RD@414999|Opitutae	414999|Opitutae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
DTH3_k127_6017077_3	1396418.BATQ01000076_gene732	4.274e-143	470.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,2ITXY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DTH3_k127_6017077_15	497964.CfE428DRAFT_4171	3.29e-20	98.0	2ETM2@1|root,33M4S@2|Bacteria,46WNN@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6017077_18	794903.OPIT5_29655	4.501e-10	71.0	COG4968@1|root,COG4968@2|Bacteria	794903.OPIT5_29655|-	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6017077_19	794903.OPIT5_09275	4.404e-09	60.0	COG2165@1|root,COG2165@2|Bacteria,46YCJ@74201|Verrucomicrobia,3K9B5@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_6027085_0	886293.Sinac_6825	8.978e-157	504.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH3_k127_6027085_2	247490.KSU1_C1333	1.277e-13	82.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_6027085_1	234267.Acid_3103	1.364e-40	152.0	COG4948@1|root,COG4948@2|Bacteria,3Y46A@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
DTH3_k127_6029359_0	661478.OP10G_0382	7.663e-168	549.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
DTH3_k127_6029359_1	1121011.AUCB01000042_gene786	3.933e-90	311.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IG0A@117743|Flavobacteriia,23IC9@178469|Arenibacter	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH3_k127_6035149_2	395961.Cyan7425_1966	2.357e-143	466.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_6035149_0	1122176.KB903544_gene705	4.987e-150	486.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,1IPJ3@117747|Sphingobacteriia	976|Bacteroidetes	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DTH3_k127_6035149_1	240292.Ava_0681	1.828e-144	466.0	COG0667@1|root,COG0667@2|Bacteria,1G3RI@1117|Cyanobacteria,1HMNR@1161|Nostocales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH3_k127_603979_0	497964.CfE428DRAFT_4290	9.478e-168	537.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH3_k127_603979_1	760192.Halhy_6498	3.166e-103	350.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,1IPQU@117747|Sphingobacteriia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
DTH3_k127_60409_11	1245475.ANAE01000143_gene4986	3.188e-05	47.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4EHIA@85012|Streptosporangiales	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
DTH3_k127_60409_4	452637.Oter_0292	7.645e-85	295.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
DTH3_k127_60409_0	497964.CfE428DRAFT_3932	9.255e-201	644.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
DTH3_k127_60409_8	497964.CfE428DRAFT_0896	4.642e-43	164.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_60409_7	497964.CfE428DRAFT_1467	3.249e-62	220.0	COG0131@1|root,COG0131@2|Bacteria,46SR2@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
DTH3_k127_60409_9	661478.OP10G_3704	3.472e-12	76.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
DTH3_k127_60409_6	886293.Sinac_6555	1.067e-67	238.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_60409_2	1442599.JAAN01000005_gene1008	9.581e-150	480.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X46C@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH3_k127_60409_1	794903.OPIT5_28445	1.351e-182	580.0	COG0677@1|root,COG0677@2|Bacteria	2|Bacteria	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	wbpA	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH3_k127_60409_3	497964.CfE428DRAFT_1446	7.323e-122	432.0	COG2133@1|root,COG2133@2|Bacteria,46UME@74201|Verrucomicrobia	74201|Verrucomicrobia	G	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH3_k127_60409_10	661478.OP10G_4722	1.018e-09	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_60409_5	1185876.BN8_04770	3.377e-77	275.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_6043649_2	767817.Desgi_4714	8.29e-20	96.0	COG0438@1|root,COG0438@2|Bacteria,1UBCE@1239|Firmicutes,24DYC@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH3_k127_6043649_1	452637.Oter_0284	9.11e-33	141.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
DTH3_k127_6043649_3	240016.ABIZ01000001_gene498	6.154e-14	82.0	2DKIU@1|root,309MI@2|Bacteria,46W7D@74201|Verrucomicrobia,2IUZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
DTH3_k127_6043649_0	497964.CfE428DRAFT_4614	4.757e-110	372.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
DTH3_k127_6048690_0	794903.OPIT5_26245	5.483e-50	181.0	COG4796@1|root,COG4796@2|Bacteria,46Y4X@74201|Verrucomicrobia,3K8XV@414999|Opitutae	414999|Opitutae	U	Bacterial type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
DTH3_k127_6048690_1	1210884.HG799463_gene10210	8.237e-09	68.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DTH3_k127_6048690_2	794903.OPIT5_26235	0.0005554	51.0	2A3EY@1|root,31MUJ@2|Bacteria,46X6D@74201|Verrucomicrobia,3K9KW@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6051673_0	1288963.ADIS_3575	8.632e-228	732.0	COG1470@1|root,COG1470@2|Bacteria,4NF75@976|Bacteroidetes	976|Bacteroidetes	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6057950_1	278957.ABEA03000104_gene310	3.228e-81	275.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
DTH3_k127_6057950_2	452637.Oter_3648	1.039e-49	190.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
DTH3_k127_6057950_0	1288963.ADIS_1776	1.575e-95	317.0	COG4409@1|root,COG4409@2|Bacteria,4NKEW@976|Bacteroidetes,47U77@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_6074698_0	1396141.BATP01000057_gene3053	9.277e-168	574.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH3_k127_6074698_1	1122176.KB903540_gene82	6.092e-07	57.0	COG0845@1|root,COG0845@2|Bacteria,4P6KC@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_3
DTH3_k127_6075285_1	933262.AXAM01000042_gene1817	4.387e-27	124.0	COG1555@1|root,COG3156@1|root,COG1555@2|Bacteria,COG3156@2|Bacteria,1PQMW@1224|Proteobacteria,42T9B@68525|delta/epsilon subdivisions,2WPYT@28221|Deltaproteobacteria,2MKAN@213118|Desulfobacterales	28221|Deltaproteobacteria	LU	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
DTH3_k127_6075285_3	1385517.N800_00590	2.098e-07	61.0	COG4795@1|root,COG4795@2|Bacteria,1MYPS@1224|Proteobacteria,1SHGQ@1236|Gammaproteobacteria,1X6ZS@135614|Xanthomonadales	135614|Xanthomonadales	U	General secretion pathway protein	xpsJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_6075285_4	1144342.PMI40_00304	0.0002146	51.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQV@28216|Betaproteobacteria,474MH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
DTH3_k127_6075285_0	483219.LILAB_20230	3.763e-72	259.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
DTH3_k127_6075285_2	485913.Krac_6839	6.892e-13	71.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
DTH3_k127_6076647_1	1235788.C802_03540	1.589e-167	552.0	COG3250@1|root,COG3250@2|Bacteria,4NEDF@976|Bacteroidetes,2FMTQ@200643|Bacteroidia,4AM6D@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH3_k127_6076647_0	886293.Sinac_0190	1.406e-212	665.0	COG3119@1|root,COG3119@2|Bacteria,2IYGF@203682|Planctomycetes	203682|Planctomycetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_6083400_2	497964.CfE428DRAFT_5015	1.443e-64	230.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
DTH3_k127_6083400_1	497964.CfE428DRAFT_0832	2.685e-89	303.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
DTH3_k127_6083400_0	794903.OPIT5_30840	4.483e-91	312.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
DTH3_k127_6085036_4	443143.GM18_4060	4.615e-15	84.0	COG2834@1|root,COG2834@2|Bacteria,1N3XP@1224|Proteobacteria,42TP4@68525|delta/epsilon subdivisions,2WQR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
DTH3_k127_6085036_1	1347393.HG726029_gene2088	1.466e-46	180.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,2FR15@200643|Bacteroidia,4AP6F@815|Bacteroidaceae	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
DTH3_k127_6085036_0	879212.DespoDRAFT_01389	1.643e-86	314.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,42PU1@68525|delta/epsilon subdivisions,2X5K4@28221|Deltaproteobacteria,2MMM5@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH3_k127_6085036_3	1121918.ARWE01000001_gene3128	8.476e-24	105.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WQ0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH3_k127_6085036_5	555779.Dthio_PD0800	9.33e-09	64.0	COG0304@1|root,COG0304@2|Bacteria,1R0WN@1224|Proteobacteria,43D2H@68525|delta/epsilon subdivisions,2X89P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ketoacyl-synt
DTH3_k127_6085036_2	443143.GM18_4055	9.351e-44	165.0	COG0304@1|root,COG0304@2|Bacteria,1RAFK@1224|Proteobacteria,42R69@68525|delta/epsilon subdivisions,2WMWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH3_k127_609185_0	759914.BP951000_2310	8.679e-31	141.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DTH3_k127_609185_1	640511.BC1002_3648	4.513e-30	131.0	COG0500@1|root,COG2226@2|Bacteria,1PI8I@1224|Proteobacteria,2W6W0@28216|Betaproteobacteria,1KCXH@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH3_k127_609185_2	292564.Cyagr_1101	0.0001502	50.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF4214,DUF4347,HemolysinCabind
DTH3_k127_6103139_0	497964.CfE428DRAFT_1603	7.691e-179	572.0	COG0673@1|root,COG0673@2|Bacteria,46TYR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_6103139_6	323261.Noc_1412	7.028e-58	208.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1X0Q2@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
DTH3_k127_6103139_4	530564.Psta_1556	1.336e-60	220.0	29525@1|root,2ZSEY@2|Bacteria,2IZ8U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6103139_5	497964.CfE428DRAFT_3900	1.212e-58	212.0	2AU2S@1|root,31JP5@2|Bacteria,46VDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_6103139_9	635013.TherJR_1860	4.712e-15	79.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DTH3_k127_6103139_2	498848.TaqDRAFT_4878	1.624e-114	394.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6103139_1	452637.Oter_1389	5.163e-166	550.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH3_k127_6103139_7	452637.Oter_2422	1.725e-56	204.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_6103139_3	452637.Oter_0016	3.658e-108	369.0	COG0530@1|root,COG0530@2|Bacteria,46Y13@74201|Verrucomicrobia,3K8RV@414999|Opitutae	414999|Opitutae	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DTH3_k127_6103139_8	583355.Caka_0236	1.457e-25	111.0	2A5NK@1|root,30UDC@2|Bacteria,46YMP@74201|Verrucomicrobia,3K9UM@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6103139_10	555793.WSK_3060	2.813e-08	65.0	COG2324@1|root,COG2324@2|Bacteria,1RA24@1224|Proteobacteria,2U67T@28211|Alphaproteobacteria,2KATD@204457|Sphingomonadales	204457|Sphingomonadales	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
DTH3_k127_6106576_0	756272.Plabr_3146	5.267e-160	511.0	COG5492@1|root,COG5492@2|Bacteria,2IYV9@203682|Planctomycetes	203682|Planctomycetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
DTH3_k127_6106576_1	1047013.AQSP01000091_gene658	7.666e-28	115.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
DTH3_k127_6112584_3	497964.CfE428DRAFT_4081	6.735e-145	477.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH3_k127_6112584_7	1396418.BATQ01000026_gene5273	5.327e-82	277.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,46TBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19
DTH3_k127_6112584_11	886293.Sinac_3116	9.049e-12	75.0	COG2165@1|root,COG2165@2|Bacteria,2IZ6K@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_6112584_0	1403819.BATR01000087_gene2529	8.919e-232	722.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DTH3_k127_6112584_4	102129.Lepto7375DRAFT_2106	1.994e-136	444.0	COG2021@1|root,COG2021@2|Bacteria,1G4G5@1117|Cyanobacteria,1HHP2@1150|Oscillatoriales	1117|Cyanobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
DTH3_k127_6112584_8	452637.Oter_0095	1.08e-68	255.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia,3K7T2@414999|Opitutae	414999|Opitutae	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6112584_9	452637.Oter_0096	2.983e-64	242.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6112584_1	1396418.BATQ01000078_gene594	8.082e-169	538.0	COG0577@1|root,COG0577@2|Bacteria,46UQN@74201|Verrucomicrobia,2IVBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_6112584_2	1403819.BATR01000150_gene5077	9.693e-155	499.0	COG0577@1|root,COG0577@2|Bacteria,46UT6@74201|Verrucomicrobia,2IVGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_6112584_6	452637.Oter_1514	7.836e-114	373.0	COG1136@1|root,COG1136@2|Bacteria,46YZ8@74201|Verrucomicrobia,3K9FX@414999|Opitutae	414999|Opitutae	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_6112584_5	1396418.BATQ01000078_gene597	3.093e-129	424.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia,2IVAY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DTH3_k127_6112584_10	452637.Oter_4609	6.507e-19	94.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DTH3_k127_6119194_3	880070.Cycma_3924	1.658e-38	156.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6119194_0	234267.Acid_0200	3.166e-281	889.0	COG3661@1|root,COG3661@2|Bacteria,3Y3Q5@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6119194_2	639030.JHVA01000001_gene3738	5.836e-89	302.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
DTH3_k127_6119194_4	1235803.C825_05233	4.373e-33	149.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes,2FY0D@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6119194_1	886293.Sinac_7494	2.21e-213	666.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_6119846_2	1121106.JQKB01000056_gene5865	5.585e-58	225.0	28MUA@1|root,2ZB28@2|Bacteria,1R8RF@1224|Proteobacteria	1224|Proteobacteria	S	Capsule biosynthesis CapC	-	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
DTH3_k127_6119846_3	1192034.CAP_6422	5.464e-12	76.0	2E205@1|root,32X8D@2|Bacteria,1N4MZ@1224|Proteobacteria,43CVC@68525|delta/epsilon subdivisions,2X83A@28221|Deltaproteobacteria,2YW05@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6125998_1	306281.AJLK01000102_gene3405	3.765e-71	246.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6125998_2	1469557.JSWF01000021_gene726	3.402e-15	84.0	COG0739@1|root,COG3266@1|root,COG4886@1|root,COG0739@2|Bacteria,COG3266@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH3_k127_6125998_4	278957.ABEA03000021_gene1719	1.129e-08	68.0	COG1520@1|root,COG1520@2|Bacteria,46Z5C@74201|Verrucomicrobia,3K9I4@414999|Opitutae	414999|Opitutae	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6125998_0	380394.Lferr_0309	4.171e-74	265.0	COG5433@1|root,COG5433@2|Bacteria,1RAHU@1224|Proteobacteria,1S1TZ@1236|Gammaproteobacteria,2NDWK@225057|Acidithiobacillales	1236|Gammaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
DTH3_k127_6125998_5	1353531.AZNX01000014_gene3212	0.0003267	46.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,2U26E@28211|Alphaproteobacteria,4BCIN@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
DTH3_k127_6125998_3	485913.Krac_7095	7.867e-10	67.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
DTH3_k127_6127624_1	383372.Rcas_2444	4.402e-24	120.0	2DQ8H@1|root,335A3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6127624_0	1316936.K678_06250	3.694e-64	229.0	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,2TU9S@28211|Alphaproteobacteria,2JPEY@204441|Rhodospirillales	204441|Rhodospirillales	P	ABC-type Co2 transport system, periplasmic component	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
DTH3_k127_6132993_0	497964.CfE428DRAFT_3635	2.694e-133	446.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
DTH3_k127_6132993_1	55529.EKX47288	5.489e-83	294.0	COG0144@1|root,KOG1122@2759|Eukaryota	2759|Eukaryota	J	rRNA (cytosine-C5-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
DTH3_k127_6143190_0	382464.ABSI01000011_gene2998	8.633e-110	363.0	COG0385@1|root,COG0385@2|Bacteria,46YXM@74201|Verrucomicrobia,2IU81@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SBF-like CPA transporter family (DUF4137)	-	-	-	-	-	-	-	-	-	-	-	-	SBF
DTH3_k127_6143190_1	497964.CfE428DRAFT_4161	1.473e-86	295.0	COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
DTH3_k127_6143190_3	583355.Caka_2132	1.881e-53	194.0	COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,3K812@414999|Opitutae	414999|Opitutae	F	Guanylate kinase	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
DTH3_k127_6143190_2	240016.ABIZ01000001_gene2279	7.766e-70	241.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,2IUB8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DTH3_k127_6150188_0	317936.Nos7107_4863	3.268e-177	569.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
DTH3_k127_6150188_1	497964.CfE428DRAFT_4695	4.064e-105	352.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DTH3_k127_6154316_0	1396141.BATP01000035_gene4047	1.89e-50	190.0	COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
DTH3_k127_6154316_1	313606.M23134_05981	1.368e-29	128.0	COG4123@1|root,COG4123@2|Bacteria,4NKPF@976|Bacteroidetes,47SG7@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH3_k127_6154316_2	1540221.JQNI01000004_gene328	7.297e-09	66.0	COG0279@1|root,COG0438@1|root,COG0279@2|Bacteria,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gmhA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_4,Glycos_transf_1,SIS_2
DTH3_k127_6163338_2	1185876.BN8_03398	0.0003891	54.0	COG2133@1|root,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_3,PA14
DTH3_k127_6163338_0	272123.Anacy_4407	6.726e-78	295.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
DTH3_k127_6163338_1	1150599.MPHLEI_02793	9.133e-30	139.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
DTH3_k127_6164443_0	497964.CfE428DRAFT_6195	4.833e-126	411.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_6164443_1	1550091.JROE01000002_gene502	3.447e-58	215.0	2DBWR@1|root,2ZBIN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
DTH3_k127_6183292_7	1216932.CM240_0570	5.144e-20	93.0	2CJFU@1|root,30ZR8@2|Bacteria,1V5NS@1239|Firmicutes,24JAT@186801|Clostridia,36RH3@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6183292_5	1089547.KB913013_gene1006	5.547e-41	155.0	COG0251@1|root,COG0251@2|Bacteria,4NR3V@976|Bacteroidetes,47QRJ@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DTH3_k127_6183292_0	765420.OSCT_3130	1.128e-65	258.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
DTH3_k127_6183292_13	102129.Lepto7375DRAFT_0067	9.822e-05	47.0	298NA@1|root,2ZVSW@2|Bacteria	2|Bacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	-
DTH3_k127_6183292_8	497964.CfE428DRAFT_0488	1.353e-19	91.0	COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DTH3_k127_6183292_3	1089553.Tph_c25840	4.462e-49	182.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42ERX@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DTH3_k127_6183292_1	1121381.JNIV01000084_gene822	3.61e-60	215.0	COG0087@1|root,COG0087@2|Bacteria,1WI2F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DTH3_k127_6183292_4	497964.CfE428DRAFT_0485	1.222e-46	169.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DTH3_k127_6183292_10	382464.ABSI01000005_gene1327	6.739e-17	81.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6183292_2	1122130.AUHN01000008_gene1512	1.493e-59	214.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH3_k127_6183292_12	1301100.HG529244_gene2342	3.268e-08	65.0	COG3103@1|root,COG3807@1|root,COG4193@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,COG4193@2|Bacteria,COG4991@2|Bacteria,1V0NC@1239|Firmicutes,25BAR@186801|Clostridia,36WMT@31979|Clostridiaceae	186801|Clostridia	GT	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
DTH3_k127_6183292_6	1236689.MMALV_01900	7.346e-26	113.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,3F2M9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DTH3_k127_6183292_11	794903.OPIT5_05255	9.946e-12	74.0	COG0457@1|root,COG1652@1|root,COG0457@2|Bacteria,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
DTH3_k127_6183292_14	243233.MCA1174	0.0002558	53.0	COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
DTH3_k127_6183292_9	497964.CfE428DRAFT_6114	1.258e-17	86.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
DTH3_k127_6192173_3	478741.JAFS01000002_gene240	0.0004845	45.0	COG1043@1|root,COG1043@2|Bacteria,46SQN@74201|Verrucomicrobia,37G0M@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH3_k127_6192173_1	296591.Bpro_2193	6.196e-79	280.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,4AB3M@80864|Comamonadaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DTH3_k127_6192173_0	944480.ATUV01000001_gene1378	2.606e-160	523.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
DTH3_k127_6192994_0	497964.CfE428DRAFT_0815	3.172e-246	767.0	COG1482@1|root,COG1482@2|Bacteria,46VQS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6192994_3	886293.Sinac_7506	2.494e-08	65.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_6192994_1	240016.ABIZ01000001_gene2350	1.437e-31	126.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH3_k127_6192994_2	240016.ABIZ01000001_gene3114	7.587e-23	106.0	2DTXG@1|root,33N3G@2|Bacteria,46WXU@74201|Verrucomicrobia,2IVTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH3_k127_6196315_2	1396141.BATP01000006_gene5432	6.323e-53	196.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH3_k127_6196315_1	1156937.MFUM_290037	3.396e-65	226.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,37GJ7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
DTH3_k127_6196315_0	452637.Oter_3478	3.533e-185	583.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
DTH3_k127_6205272_3	497964.CfE428DRAFT_3025	1.344e-42	165.0	COG0500@1|root,COG0500@2|Bacteria,46SYP@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
DTH3_k127_6205272_2	598467.BrE312_1653	3.236e-68	238.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DTH3_k127_6205272_1	1156937.MFUM_1020047	3.787e-85	301.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,37G6B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	MacB-like periplasmic core domain	lolE	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DTH3_k127_6205272_4	237368.SCABRO_02994	1.103e-26	120.0	COG2930@1|root,COG2930@2|Bacteria,2IZZF@203682|Planctomycetes	203682|Planctomycetes	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
DTH3_k127_6205272_0	1122176.KB903609_gene5148	8.007e-114	391.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_6212989_0	497964.CfE428DRAFT_1743	9.596e-267	835.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
DTH3_k127_6212989_1	497964.CfE428DRAFT_0749	1.439e-87	297.0	COG0327@1|root,COG0327@2|Bacteria	2|Bacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
DTH3_k127_6212989_3	1403819.BATR01000133_gene4737	0.0002693	50.0	2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia,2IUKT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6212989_2	880072.Desac_1280	2.43e-58	213.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MQGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DTH3_k127_6233978_1	313628.LNTAR_22814	1.753e-154	506.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
DTH3_k127_6233978_0	1454007.JAUG01000073_gene4094	2.805e-167	548.0	COG2247@1|root,COG2247@2|Bacteria,4P17J@976|Bacteroidetes	976|Bacteroidetes	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5013
DTH3_k127_6233978_2	1380346.JNIH01000059_gene68	6.729e-10	66.0	COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria	201174|Actinobacteria	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
DTH3_k127_6235727_0	1396141.BATP01000060_gene4727	1.357e-161	545.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
DTH3_k127_6235727_1	243231.GSU0891	1.104e-09	70.0	COG1361@1|root,COG1404@1|root,COG5549@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG5549@2|Bacteria,1RC5K@1224|Proteobacteria,42U2I@68525|delta/epsilon subdivisions,2WQAT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH3_k127_623637_2	498761.HM1_0137	8.044e-24	109.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
DTH3_k127_623637_0	344747.PM8797T_02174	1.148e-120	405.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_623637_1	344747.PM8797T_02169	7.865e-65	227.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
DTH3_k127_6243145_1	404380.Gbem_3513	3.178e-37	153.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
DTH3_k127_6243145_3	335543.Sfum_0754	0.00054	51.0	COG0810@1|root,COG0810@2|Bacteria,1Q5Z4@1224|Proteobacteria,43A9M@68525|delta/epsilon subdivisions,2X230@28221|Deltaproteobacteria,2MQPN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
DTH3_k127_6243145_2	497964.CfE428DRAFT_5287	1.76e-21	99.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH3_k127_6243145_0	497964.CfE428DRAFT_5288	3.26e-45	172.0	COG0811@1|root,COG0811@2|Bacteria,46V4I@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
DTH3_k127_6243725_3	1121439.dsat_0388	1.498e-34	146.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MG89@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH3_k127_6243725_2	204669.Acid345_1377	2.742e-64	232.0	COG0385@1|root,COG0385@2|Bacteria,3Y8P2@57723|Acidobacteria,2JNM2@204432|Acidobacteriia	204432|Acidobacteriia	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
DTH3_k127_6243725_1	335543.Sfum_1471	2.222e-310	966.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,2MQ9F@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
DTH3_k127_6243725_0	420324.KI912022_gene340	0.0	1219.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,1JT1D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
DTH3_k127_6246841_3	1267534.KB906754_gene3774	2.818e-43	160.0	COG0713@1|root,COG0713@2|Bacteria,3Y835@57723|Acidobacteria,2JN5T@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
DTH3_k127_6246841_2	1267534.KB906754_gene3775	8.835e-46	171.0	COG0839@1|root,COG0839@2|Bacteria,3Y84Z@57723|Acidobacteria,2JN7E@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DTH3_k127_6246841_0	1267534.KB906754_gene3776	5.616e-164	524.0	COG1005@1|root,COG1005@2|Bacteria,3Y6TS@57723|Acidobacteria,2JKJQ@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DTH3_k127_6246841_1	1267534.KB906754_gene3777	5.488e-71	243.0	COG1143@1|root,COG1143@2|Bacteria,3Y6N6@57723|Acidobacteria,2JKQS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
DTH3_k127_6249865_0	1303518.CCALI_00290	0.0	1068.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DTH3_k127_6249865_1	583355.Caka_1736	2.038e-180	603.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_6253494_4	1123393.KB891317_gene2240	4.174e-20	92.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,1KSYV@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Ferrous iron transport protein B C terminus	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_C,FeoB_N,Gate
DTH3_k127_6253494_5	497964.CfE428DRAFT_6371	5.824e-17	83.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
DTH3_k127_6253494_8	452637.Oter_0873	6.772e-06	52.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
DTH3_k127_6253494_7	608538.HTH_0820	6.1e-08	58.0	COG0268@1|root,COG0268@2|Bacteria,2G49M@200783|Aquificae	200783|Aquificae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
DTH3_k127_6253494_1	88036.EFJ24329	8.648e-57	206.0	COG0637@1|root,KOG2177@1|root,KOG2177@2759|Eukaryota,KOG2914@2759|Eukaryota,37MAK@33090|Viridiplantae,3GD1A@35493|Streptophyta	35493|Streptophyta	O	NHL repeat-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066	-	-	-	-	-	-	-	-	-	-	HAD_2,NHL,Thioredoxin_8
DTH3_k127_6253494_2	1168034.FH5T_19355	1.1e-47	184.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_6253494_3	1123242.JH636435_gene1168	3.952e-25	113.0	COG1413@1|root,COG1413@2|Bacteria,2J2I0@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_6253494_0	547042.BACCOPRO_00992	7.475e-122	419.0	COG1572@1|root,COG1572@2|Bacteria,4PJMZ@976|Bacteroidetes,2FZ9J@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
DTH3_k127_6253494_6	1499967.BAYZ01000177_gene5729	5.018e-16	78.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
DTH3_k127_6266289_0	1132441.KI519454_gene1142	2.338e-269	853.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6267477_0	661478.OP10G_2146	1.775e-269	857.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH3_k127_6267477_1	1211813.CAPH01000018_gene935	2.358e-05	49.0	COG3754@1|root,COG3754@2|Bacteria,4P1NY@976|Bacteroidetes,2FRFT@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX
DTH3_k127_6281652_0	1123508.JH636445_gene6725	3.086e-232	740.0	COG1621@1|root,COG1621@2|Bacteria,2IXNN@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 32	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
DTH3_k127_6281652_1	886293.Sinac_2434	1.533e-157	514.0	COG2730@1|root,COG3250@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
DTH3_k127_6281652_2	1396418.BATQ01000049_gene432	1.506e-45	176.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_628326_1	573413.Spirs_4004	1.037e-12	72.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DTH3_k127_628326_0	452637.Oter_0650	5.932e-25	120.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6288086_2	497964.CfE428DRAFT_3450	2.069e-55	203.0	COG2096@1|root,COG2096@2|Bacteria,46T1G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
DTH3_k127_6288086_4	452637.Oter_3173	1.948e-36	145.0	2EFI3@1|root,339AJ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
DTH3_k127_6288086_3	497964.CfE428DRAFT_1664	3.775e-37	151.0	COG1985@1|root,COG1985@2|Bacteria,46WC6@74201|Verrucomicrobia	74201|Verrucomicrobia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
DTH3_k127_6288086_0	545693.BMQ_4641	3.923e-103	347.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,1ZB71@1386|Bacillus	91061|Bacilli	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DTH3_k127_6288086_7	315456.RF_0905	2.56e-13	77.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,47FG2@766|Rickettsiales	766|Rickettsiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
DTH3_k127_6288086_1	1382356.JQMP01000004_gene475	5.839e-74	259.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
DTH3_k127_6288086_5	203119.Cthe_0979	2.268e-22	108.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH3_k127_6293038_0	452637.Oter_4534	0.0	1441.0	COG0458@1|root,COG0458@2|Bacteria,46UZV@74201|Verrucomicrobia,3K7MQ@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH3_k127_6295723_0	497964.CfE428DRAFT_0983	1.175e-108	354.0	COG1524@1|root,COG1524@2|Bacteria,46TI1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_6295723_1	886293.Sinac_4427	9.757e-108	360.0	COG3023@1|root,COG3023@2|Bacteria,2J257@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
DTH3_k127_6295723_2	521674.Plim_0037	1.817e-92	320.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_6300851_4	1403819.BATR01000191_gene6566	9.179e-44	160.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,2ITQE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DTH3_k127_6300851_7	59374.Fisuc_1277	7.689e-06	53.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
DTH3_k127_6300851_2	278957.ABEA03000094_gene4759	2.669e-59	212.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,3K7UE@414999|Opitutae	414999|Opitutae	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
DTH3_k127_6300851_1	1156937.MFUM_210036	1.831e-62	217.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,37GN5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DTH3_k127_6300851_0	497964.CfE428DRAFT_5605	9.259e-87	294.0	COG0081@1|root,COG0081@2|Bacteria,46S7K@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DTH3_k127_6300851_3	1403819.BATR01000191_gene6561	3.397e-45	169.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DTH3_k127_6300851_5	1532558.JL39_13770	6.049e-17	82.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,4BESI@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
DTH3_k127_6306628_4	269084.syc1734_d	6.442e-67	238.0	COG1043@1|root,COG1043@2|Bacteria,1G3IU@1117|Cyanobacteria,1H2QC@1129|Synechococcus	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DTH3_k127_6306628_5	1121468.AUBR01000001_gene497	1.102e-52	194.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
DTH3_k127_6306628_7	1177154.Y5S_00007	8.499e-14	83.0	2FA92@1|root,342HR@2|Bacteria,1NYCG@1224|Proteobacteria,1SQ6S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6306628_2	497964.CfE428DRAFT_2172	2.188e-103	352.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DTH3_k127_6306628_6	478741.JAFS01000001_gene1519	5.094e-37	141.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,37GX8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
DTH3_k127_6306628_3	485916.Dtox_1215	1.473e-101	350.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH3_k127_6306628_0	1156937.MFUM_940006	1.497e-125	419.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,37GAQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DTH3_k127_6306628_1	1156937.MFUM_940007	8.327e-119	396.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,37GBS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DTH3_k127_6307057_0	1122605.KB893625_gene1683	4.057e-183	589.0	COG1501@1|root,COG1501@2|Bacteria,4PKHN@976|Bacteroidetes,1IP35@117747|Sphingobacteriia	976|Bacteroidetes	G	He_PIG associated, NEW1 domain of bacterial glycohydrolase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	He_PIG,He_PIG_assoc,Melibiase_2,NPCBM
DTH3_k127_6307057_3	935839.JAGJ01000024_gene2469	3.679e-26	124.0	COG0737@1|root,COG3250@1|root,COG3934@1|root,COG4409@1|root,COG0737@2|Bacteria,COG3250@2|Bacteria,COG3934@2|Bacteria,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,DUF4091,F5_F8_type_C,NPCBM,NPCBM_assoc
DTH3_k127_6307057_2	1122915.AUGY01000073_gene4393	5.649e-39	164.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,4IT8Q@91061|Bacilli,277AM@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH3_k127_6307057_5	1303518.CCALI_02493	9.535e-09	66.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_6307057_1	1089553.Tph_c09100	4.801e-98	338.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH3_k127_6307057_7	1089553.Tph_c09110	0.0002461	53.0	2CJTW@1|root,33NBH@2|Bacteria,1VM99@1239|Firmicutes,24UVS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6307057_4	1496688.ER33_07850	3.799e-17	96.0	COG2931@1|root,COG3209@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
DTH3_k127_6307057_6	1496688.ER33_07850	1.143e-06	59.0	COG2931@1|root,COG3209@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1G39H@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,HemolysinCabind,RHS_repeat
DTH3_k127_6318557_1	886293.Sinac_4612	5.037e-58	203.0	2BZ6M@1|root,2Z7HW@2|Bacteria,2IXV4@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_6318557_0	429009.Adeg_0126	5.71e-115	389.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,42ES5@68295|Thermoanaerobacterales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DTH3_k127_6328490_1	1532558.JL39_15420	4.405e-119	387.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,4B9AV@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH3_k127_6328490_2	1268068.PG5_33320	9.242e-107	361.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
DTH3_k127_6328490_4	525897.Dbac_1089	6.626e-55	199.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria,2MFM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6328490_3	575540.Isop_2535	4.759e-75	262.0	COG0580@1|root,COG0580@2|Bacteria,2IZDN@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DTH3_k127_6328490_5	522306.CAP2UW1_1267	1.6e-18	93.0	2EBP0@1|root,335P6@2|Bacteria,1N33Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6328490_0	1123242.JH636436_gene23	3.12e-155	506.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_6333129_3	240016.ABIZ01000001_gene3616	1.769e-59	214.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_6333129_1	497964.CfE428DRAFT_2060	7.402e-75	263.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
DTH3_k127_6333129_0	118166.JH976538_gene5057	2.475e-92	327.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
DTH3_k127_6333129_4	886293.Sinac_0920	4.106e-14	78.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_6333129_2	452637.Oter_0712	1.528e-63	237.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
DTH3_k127_6352458_0	497964.CfE428DRAFT_2425	0.0	1234.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U71@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Laminin_G_3
DTH3_k127_6352458_1	595460.RRSWK_04420	2.242e-119	400.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
DTH3_k127_6354909_2	272134.KB731324_gene6611	5.33e-67	258.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
DTH3_k127_6354909_0	1121930.AQXG01000003_gene2719	5.616e-103	347.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
DTH3_k127_6354909_1	1449126.JQKL01000018_gene3257	8.674e-84	287.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,268GC@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
DTH3_k127_6360566_2	926549.KI421517_gene3311	8.421e-43	175.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH3_k127_6360566_0	530564.Psta_3017	2.829e-257	808.0	COG1053@1|root,COG1053@2|Bacteria,2IXHQ@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
DTH3_k127_6360566_5	1123278.KB893612_gene4471	4.924e-15	82.0	COG3415@1|root,COG3415@2|Bacteria,4PPRX@976|Bacteroidetes,47YRE@768503|Cytophagia	976|Bacteroidetes	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_33
DTH3_k127_6360566_4	66429.JOFL01000024_gene5986	1.668e-18	94.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
DTH3_k127_6360566_3	497964.CfE428DRAFT_3194	3.89e-35	141.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DTH3_k127_6360566_1	1123242.JH636434_gene5339	1.661e-65	229.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_6368114_0	452637.Oter_0138	5.648e-168	547.0	COG3934@1|root,COG3934@2|Bacteria,46YQT@74201|Verrucomicrobia,3KA0N@414999|Opitutae	414999|Opitutae	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6368114_4	497964.CfE428DRAFT_2588	4.707e-40	162.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH3_k127_6368114_1	497964.CfE428DRAFT_3386	3.513e-104	345.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
DTH3_k127_6368114_5	497964.CfE428DRAFT_2343	3.845e-31	130.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
DTH3_k127_6368114_6	1353529.M899_0700	1.099e-19	89.0	COG0267@1|root,COG0267@2|Bacteria,1Q1V0@1224|Proteobacteria,437HE@68525|delta/epsilon subdivisions,2MTDQ@213481|Bdellovibrionales,2X2QY@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
DTH3_k127_6368114_7	497964.CfE428DRAFT_2341	3.871e-13	77.0	COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein S18	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DTH3_k127_6368114_3	5786.XP_003293123.1	6.983e-66	244.0	COG1409@1|root,KOG1378@2759|Eukaryota,3XGP6@554915|Amoebozoa	554915|Amoebozoa	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Pur_ac_phosph_N
DTH3_k127_6368114_2	240016.ABIZ01000001_gene2631	4.671e-83	294.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH3_k127_6378927_1	1303518.CCALI_00184	1.079e-145	492.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	galA	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_4_9,CBM_6,DUF1565
DTH3_k127_6378927_0	240016.ABIZ01000001_gene3202	5.854e-178	569.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH3_k127_6378927_2	1396141.BATP01000062_gene4448	1.638e-145	479.0	COG2939@1|root,COG2939@2|Bacteria,46UB7@74201|Verrucomicrobia,2IVCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
DTH3_k127_6378927_4	497964.CfE428DRAFT_5038	3.831e-110	371.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DTH3_k127_6378927_9	497964.CfE428DRAFT_3571	2.133e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,46VJX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DTH3_k127_6378927_8	759914.BP951000_1517	8.379e-25	123.0	COG0457@1|root,COG0457@2|Bacteria	759914.BP951000_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6378927_7	497964.CfE428DRAFT_3654	2.55e-35	143.0	COG0576@1|root,COG0576@2|Bacteria,46T79@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH3_k127_6378927_3	382464.ABSI01000010_gene3750	1.169e-139	453.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DTH3_k127_6378927_5	497964.CfE428DRAFT_3657	1.675e-64	229.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
DTH3_k127_6378927_6	240016.ABIZ01000001_gene402	1.925e-41	164.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,2IU90@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
DTH3_k127_6396403_0	1267535.KB906767_gene3736	2.073e-145	467.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH3_k127_6396403_3	497964.CfE428DRAFT_4858	8.954e-33	132.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH3_k127_6396403_1	1158292.JPOE01000002_gene3555	1.578e-56	200.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH3_k127_639700_0	452637.Oter_1374	1.513e-224	706.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
DTH3_k127_639700_1	1122917.KB899665_gene3972	2.576e-97	324.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,26W35@186822|Paenibacillaceae	91061|Bacilli	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH3_k127_6408457_0	1123242.JH636436_gene628	2.599e-167	538.0	COG1502@1|root,COG1502@2|Bacteria,2IY2H@203682|Planctomycetes	203682|Planctomycetes	I	Phospholipase_D-nuclease N-terminal	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
DTH3_k127_6408457_1	1192034.CAP_8492	1.395e-07	55.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,43C30@68525|delta/epsilon subdivisions,2X7DN@28221|Deltaproteobacteria,2YUXV@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
DTH3_k127_6413672_1	1185876.BN8_01260	1.887e-114	373.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH3_k127_6413672_2	247490.KSU1_C1131	8.832e-58	207.0	COG1881@1|root,COG1881@2|Bacteria,2J1MM@203682|Planctomycetes	203682|Planctomycetes	G	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP,YHYH
DTH3_k127_6413672_0	886293.Sinac_3465	2.056e-168	542.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH3_k127_6413672_3	497964.CfE428DRAFT_0286	5.251e-23	100.0	2DR28@1|root,339V9@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
DTH3_k127_6414730_2	1123073.KB899242_gene1477	7.811e-81	280.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DTH3_k127_6414730_1	1396418.BATQ01000106_gene5309	4.69e-120	395.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH3_k127_6414730_4	314256.OG2516_10581	4.585e-05	53.0	COG3637@1|root,COG3637@2|Bacteria,1RBBG@1224|Proteobacteria,2U5ED@28211|Alphaproteobacteria,2PE89@252301|Oceanicola	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	lpxQ	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl
DTH3_k127_6414730_0	1396141.BATP01000009_gene2657	1.224e-128	415.0	COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia,2ITYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiazole biosynthesis protein ThiG	-	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
DTH3_k127_6414730_3	1396418.BATQ01000015_gene4297	1.154e-70	250.0	COG2870@1|root,COG2870@2|Bacteria,46T1J@74201|Verrucomicrobia,2IVXQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
DTH3_k127_6421192_2	194439.CT1903	2.726e-19	87.0	COG1032@1|root,COG1032@2|Bacteria,1FEJ6@1090|Chlorobi	1090|Chlorobi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH3_k127_6421192_1	1123073.KB899241_gene3250	5.471e-146	472.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH3_k127_6421192_0	880072.Desac_1063	9.929e-259	807.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MS34@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH3_k127_6426999_4	471854.Dfer_0095	1.665e-29	123.0	COG1680@1|root,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,47N9R@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
DTH3_k127_6426999_0	240016.ABIZ01000001_gene2202	1.356e-105	351.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
DTH3_k127_6426999_7	794903.OPIT5_02510	3.364e-05	46.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH3_k127_6426999_2	1140.Synpcc7942_1288	3.052e-42	162.0	COG3831@1|root,COG3831@2|Bacteria,1GPKY@1117|Cyanobacteria,1H3GN@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF4240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4240
DTH3_k127_6426999_5	935567.JAES01000033_gene858	1.37e-20	93.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,1SJFZ@1236|Gammaproteobacteria,1X82Y@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6426999_1	1403819.BATR01000104_gene3538	1.949e-87	302.0	COG3618@1|root,COG3618@2|Bacteria,46SN7@74201|Verrucomicrobia,2IUQ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH3_k127_6426999_3	1499967.BAYZ01000137_gene111	1.115e-31	132.0	2FGP7@1|root,348IT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6430386_4	1403819.BATR01000092_gene2782	9.853e-07	51.0	COG2103@1|root,COG2971@1|root,COG2103@2|Bacteria,COG2971@2|Bacteria,46SJI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,SIS_2
DTH3_k127_6430386_6	481448.Minf_0311	0.0001275	48.0	COG2919@1|root,COG2919@2|Bacteria,46ZEA@74201|Verrucomicrobia,37GXB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
DTH3_k127_6430386_2	1403819.BATR01000057_gene1783	1.063e-54	198.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DTH3_k127_6430386_1	1142394.PSMK_12900	1.963e-86	310.0	COG2103@1|root,COG2103@2|Bacteria	2|Bacteria	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
DTH3_k127_6430386_5	247490.KSU1_D0453	6.142e-05	47.0	2EGSE@1|root,33AII@2|Bacteria,2J3TB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6430386_3	329726.AM1_2164	2.976e-16	81.0	COG1100@1|root,COG2319@1|root,COG4916@1|root,COG1100@2|Bacteria,COG2319@2|Bacteria,COG4916@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
DTH3_k127_6430386_0	1265505.ATUG01000002_gene1309	8.151e-91	305.0	COG0160@1|root,COG0160@2|Bacteria,1QTZ3@1224|Proteobacteria,43D42@68525|delta/epsilon subdivisions,2X8AU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DTH3_k127_6431759_1	497964.CfE428DRAFT_5191	3.874e-195	613.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DTH3_k127_6431759_5	481448.Minf_2177	1.437e-34	135.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DTH3_k127_6431759_0	497964.CfE428DRAFT_5188	1.599e-300	933.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DTH3_k127_6431759_4	497964.CfE428DRAFT_1521	1.176e-65	229.0	COG0461@1|root,COG0461@2|Bacteria,46SZV@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
DTH3_k127_6431759_2	243233.MCA2830	1.214e-145	475.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
DTH3_k127_6431759_3	1454004.AW11_00497	3.543e-69	237.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DTH3_k127_6433151_1	530564.Psta_3178	5.995e-171	555.0	COG2010@1|root,COG2010@2|Bacteria,2IXTE@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_6433151_0	497964.CfE428DRAFT_3580	3.032e-233	730.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_6440727_1	497964.CfE428DRAFT_2630	1.055e-95	324.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6440727_2	497964.CfE428DRAFT_2630	6.489e-08	60.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6440727_0	1403819.BATR01000162_gene5307	2.758e-158	506.0	COG4260@1|root,COG4260@2|Bacteria,46UVR@74201|Verrucomicrobia,2IV4M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17
DTH3_k127_6441105_4	948106.AWZT01000019_gene3975	3.641e-08	59.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2VXXB@28216|Betaproteobacteria,1K9C3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
DTH3_k127_6441105_5	1387312.BAUS01000002_gene286	3.742e-05	53.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
DTH3_k127_6441105_3	497964.CfE428DRAFT_5990	1.136e-60	218.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_6441105_2	716544.wcw_0442	2.299e-125	408.0	COG1028@1|root,COG1028@2|Bacteria,2JG7F@204428|Chlamydiae	204428|Chlamydiae	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
DTH3_k127_6441105_0	1496688.ER33_11555	3.451e-250	789.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
DTH3_k127_6441105_1	1454004.AW11_02080	1.136e-168	539.0	COG0166@1|root,COG0166@2|Bacteria,1PQU4@1224|Proteobacteria,2VKX3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the GPI family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6454154_3	762982.HMPREF9442_03115	8.752e-87	300.0	COG3534@1|root,COG3534@2|Bacteria,4NHR5@976|Bacteroidetes,2G2XU@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
DTH3_k127_6454154_5	180332.JTGN01000003_gene1990	1.5e-79	278.0	COG0407@1|root,COG0407@2|Bacteria,1TW8J@1239|Firmicutes,24BSH@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH3_k127_6454154_1	313628.LNTAR_20082	7.272e-135	441.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yteT	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_6454154_4	314230.DSM3645_20877	2.36e-85	292.0	COG1506@1|root,COG2755@1|root,COG1506@2|Bacteria,COG2755@2|Bacteria,2J4YR@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_6454154_2	1211813.CAPH01000001_gene1170	7.882e-127	437.0	COG3345@1|root,COG3345@2|Bacteria,4NZUR@976|Bacteroidetes,2FNUD@200643|Bacteroidia	976|Bacteroidetes	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
DTH3_k127_6454154_6	1121381.JNIV01000032_gene2525	1.537e-09	72.0	COG3055@1|root,COG3250@1|root,COG3055@2|Bacteria,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060,Kelch_1,Kelch_6,NPCBM,SpoIIE
DTH3_k127_6454154_0	1077285.AGDG01000045_gene2975	2.085e-263	846.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_6454154_7	1121403.AUCV01000014_gene4604	0.0003987	44.0	COG3420@1|root,COG3420@2|Bacteria,1NIRV@1224|Proteobacteria	1224|Proteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DTH3_k127_64563_2	886293.Sinac_0803	7.186e-05	53.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
DTH3_k127_64563_0	1125863.JAFN01000001_gene1123	5.715e-85	293.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DTH3_k127_64563_1	1396141.BATP01000057_gene2939	1.037e-52	201.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	cqsA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K10915	ko00260,ko00780,ko01100,ko02024,ko05111,map00260,map00780,map01100,map02024,map05111	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding
DTH3_k127_6457517_1	1150474.JQJI01000004_gene436	7.124e-94	316.0	COG1087@1|root,COG1087@2|Bacteria,2GCQI@200918|Thermotogae	200918|Thermotogae	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH3_k127_6457517_3	479434.Sthe_2210	1.556e-75	267.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27XZ7@189775|Thermomicrobia	200795|Chloroflexi	E	TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DTH3_k127_6457517_5	47839.CCAU010000018_gene4176	0.000313	53.0	COG2244@1|root,COG2244@2|Bacteria,2I8M1@201174|Actinobacteria,2372Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6457517_4	391623.TERMP_00885	1.29e-46	178.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_6457517_0	382464.ABSI01000010_gene3676	2.629e-153	497.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,2IU0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
DTH3_k127_6457517_2	1156937.MFUM_1010094	3.87e-92	316.0	COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia,37FVR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Probable RNA and SrmB- binding site of polymerase A	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
DTH3_k127_6469848_1	1131269.AQVV01000004_gene610	0.0005061	44.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K01802,ko:K03770,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
DTH3_k127_6469848_0	247490.KSU1_D0577	1.831e-304	944.0	COG0243@1|root,COG0243@2|Bacteria,2J2QN@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin
DTH3_k127_6486494_1	313628.LNTAR_20062	6.452e-09	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_6486494_0	382464.ABSI01000013_gene1723	5.715e-101	353.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
DTH3_k127_6487896_3	477974.Daud_0708	3.281e-20	92.0	COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,249A1@186801|Clostridia,26567@186807|Peptococcaceae	186801|Clostridia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DTH3_k127_6487896_4	1112212.JH584235_gene3224	4.056e-13	73.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TRE4@28211|Alphaproteobacteria,2K22C@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat,N6_N4_Mtase
DTH3_k127_6487896_0	398767.Glov_2515	2.259e-41	160.0	2DGUS@1|root,32U80@2|Bacteria,1MZK3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6487896_5	443254.Marpi_0296	8.045e-08	56.0	COG1715@1|root,COG2189@1|root,COG1715@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07316,ko:K07448	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,Mrr_N,Mrr_cat,N6_N4_Mtase
DTH3_k127_6487896_2	1499967.BAYZ01000088_gene5060	6.212e-28	120.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
DTH3_k127_6487896_7	935567.JAES01000002_gene626	1.79e-05	51.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6487896_6	670307.HYPDE_29893	1.086e-05	54.0	2FH9D@1|root,3493Q@2|Bacteria,1ND9G@1224|Proteobacteria,2UJ2Y@28211|Alphaproteobacteria,3N997@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
DTH3_k127_6487896_1	686340.Metal_2200	2.021e-34	144.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6508205_0	1540221.JQNI01000002_gene1751	8.43e-06	58.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
DTH3_k127_6511765_2	1288494.EBAPG3_29430	1.198e-32	134.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2VI0M@28216|Betaproteobacteria,372R4@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Polysaccharide biosynthesis protein	wbpP	-	5.1.3.6,5.1.3.7	ko:K02473,ko:K08679	ko00520,ko01100,map00520,map01100	-	R00418,R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH3_k127_6511765_1	497964.CfE428DRAFT_4990	1.071e-66	248.0	COG3071@1|root,COG3071@2|Bacteria,46VFP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6511765_0	1122176.KB903598_gene4712	3.76e-113	387.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
DTH3_k127_6516219_10	1379698.RBG1_1C00001G0366	3.06e-06	59.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	Reg_prop,Y_Y_Y
DTH3_k127_6516219_7	485918.Cpin_0414	1.841e-60	212.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
DTH3_k127_6516219_8	794903.OPIT5_13650	7.066e-20	103.0	2AXAG@1|root,30YNX@2|Bacteria,46YVC@74201|Verrucomicrobia,3K96I@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6516219_9	164757.Mjls_1689	2.241e-07	59.0	COG3583@1|root,COG3666@1|root,COG3583@2|Bacteria,COG3666@2|Bacteria,2H4RU@201174|Actinobacteria,235V0@1762|Mycobacteriaceae	201174|Actinobacteria	L	Resuscitation-promoting factor rpfB	rpfB	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
DTH3_k127_6516219_4	483219.LILAB_30160	1.494e-154	498.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
DTH3_k127_6516219_2	497964.CfE428DRAFT_4597	3.24e-231	726.0	COG4108@1|root,COG4108@2|Bacteria,46SF9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
DTH3_k127_6516219_5	62928.azo2300	1.285e-138	452.0	COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,2VH3A@28216|Betaproteobacteria,2KVZG@206389|Rhodocyclales	206389|Rhodocyclales	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
DTH3_k127_6516219_0	595460.RRSWK_04657	1.146e-271	843.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
DTH3_k127_6516219_1	1123242.JH636435_gene1179	8.946e-261	812.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_6516219_3	521674.Plim_1566	2.28e-223	710.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
DTH3_k127_6516219_6	240016.ABIZ01000001_gene5457	2.715e-127	413.0	COG3119@1|root,COG3119@2|Bacteria,46U45@74201|Verrucomicrobia,2IV5A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_6523383_1	497964.CfE428DRAFT_5616	3.726e-90	308.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
DTH3_k127_6523383_2	1283300.ATXB01000001_gene1507	7.624e-41	158.0	COG4636@1|root,COG4636@2|Bacteria,1R58B@1224|Proteobacteria,1S53A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DTH3_k127_6523383_0	1396141.BATP01000043_gene1929	3.526e-252	833.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_6530212_0	1274374.CBLK010000061_gene596	1.529e-100	338.0	2CAEK@1|root,2ZCPG@2|Bacteria,1U07Z@1239|Firmicutes,4I9IQ@91061|Bacilli,271MJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6530212_1	1123242.JH636435_gene2066	5.917e-45	178.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DTH3_k127_6544725_3	794903.OPIT5_10630	4.445e-18	96.0	COG2133@1|root,COG3266@1|root,COG5184@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria,COG5184@2|Bacteria,46Z90@74201|Verrucomicrobia,3K9IV@414999|Opitutae	414999|Opitutae	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH3_k127_6544725_0	344747.PM8797T_02169	4.262e-146	489.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
DTH3_k127_6544725_1	344747.PM8797T_26205	1.254e-51	206.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,PQQ,PQQ_2,PQQ_3
DTH3_k127_6544725_2	1123242.JH636435_gene2613	4.576e-39	154.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH3_k127_6559554_1	596151.DesfrDRAFT_2486	4.138e-59	208.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42U59@68525|delta/epsilon subdivisions,2WRMP@28221|Deltaproteobacteria,2M8XT@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
DTH3_k127_6559554_0	1267535.KB906767_gene3116	1.348e-175	565.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JKYS@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH3_k127_6570605_0	452637.Oter_1374	2.171e-82	278.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
DTH3_k127_6591227_1	1173028.ANKO01000195_gene5986	2.489e-104	350.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
DTH3_k127_6591227_0	1121017.AUFG01000010_gene1661	1.413e-174	557.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4FEQ1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DTH3_k127_6597454_2	497964.CfE428DRAFT_2711	8.231e-88	306.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
DTH3_k127_6597454_0	344747.PM8797T_07534	3.471e-175	561.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6597454_1	1156937.MFUM_690053	1.168e-118	392.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,37G5N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
DTH3_k127_6597454_4	497964.CfE428DRAFT_3455	4.229e-40	164.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
DTH3_k127_6597454_3	497964.CfE428DRAFT_3455	3.611e-71	255.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
DTH3_k127_6597454_5	1211813.CAPH01000017_gene773	1.661e-37	156.0	COG3408@1|root,COG3408@2|Bacteria,4P4HZ@976|Bacteroidetes	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6607887_1	240016.ABIZ01000001_gene3538	1.788e-56	225.0	COG2755@1|root,COG2755@2|Bacteria,46WAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6607887_0	1203550.HMPREF1475_00695	4.728e-111	394.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,2FPXE@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
DTH3_k127_6609923_0	497964.CfE428DRAFT_5324	0.0	1069.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
DTH3_k127_6609923_3	278957.ABEA03000106_gene1817	9.457e-07	60.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6609923_2	452637.Oter_0300	2.066e-22	108.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF3379
DTH3_k127_6609923_1	452637.Oter_0299	1.663e-45	170.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_6610319_0	240016.ABIZ01000001_gene5219	6.855e-11	74.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
DTH3_k127_6613310_5	886293.Sinac_3103	1.723e-83	287.0	COG1082@1|root,COG1082@2|Bacteria,2IZ3D@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_6613310_6	1403819.BATR01000118_gene4116	8.163e-76	265.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
DTH3_k127_6613310_1	1499967.BAYZ01000093_gene4011	2.022e-157	505.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
DTH3_k127_6613310_3	1166018.FAES_2374	2.049e-119	388.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
DTH3_k127_6613310_8	667014.Thein_1367	4.513e-42	162.0	COG0563@1|root,COG0563@2|Bacteria,2GI9A@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Adenylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	ADK
DTH3_k127_6613310_0	478741.JAFS01000001_gene1962	3.775e-169	551.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,37G93@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH3_k127_6613310_4	1396141.BATP01000060_gene4695	1.082e-98	337.0	COG0546@1|root,COG1051@1|root,COG0546@2|Bacteria,COG1051@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX
DTH3_k127_6613310_10	1132855.KB913035_gene572	6.469e-15	79.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,2KMXM@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
DTH3_k127_6613310_7	1500893.JQNB01000001_gene1609	1.119e-48	179.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1SBBF@1236|Gammaproteobacteria,1XDAF@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DTH3_k127_6613310_12	1303518.CCALI_00340	2.432e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_6613310_2	861299.J421_6202	4.704e-128	424.0	COG1064@1|root,COG1064@2|Bacteria,1ZSXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DTH3_k127_6613310_9	1303518.CCALI_02638	5.14e-16	89.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_6613310_11	1303518.CCALI_02295	7.2e-14	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_6619028_0	497964.CfE428DRAFT_0827	4.103e-90	301.0	COG2223@1|root,COG2223@2|Bacteria,46UH2@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_6626684_1	886293.Sinac_7498	4.469e-188	609.0	COG2010@1|root,COG2010@2|Bacteria,2IXZ4@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_6626684_2	1287276.X752_02890	5.125e-89	306.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2UQQC@28211|Alphaproteobacteria,43N9M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
DTH3_k127_6626684_3	530564.Psta_3458	6.374e-70	251.0	COG1416@1|root,COG4798@1|root,COG1416@2|Bacteria,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
DTH3_k127_6626684_0	1396141.BATP01000040_gene2167	0.0	1326.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH3_k127_6626684_4	497964.CfE428DRAFT_2506	3.449e-20	90.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DTH3_k127_6628934_1	521674.Plim_3726	4.571e-15	80.0	COG2165@1|root,COG2165@2|Bacteria,2IYN2@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_6628934_2	1123242.JH636434_gene5550	4.437e-07	60.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_6628934_0	1403819.BATR01000195_gene6595	5.929e-33	133.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
DTH3_k127_6628934_3	265311.Mfl382	0.0004873	46.0	COG0204@1|root,COG0204@2|Bacteria,3WTAB@544448|Tenericutes	544448|Tenericutes	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DTH3_k127_6631408_1	794903.OPIT5_20525	5.249e-81	275.0	COG1943@1|root,COG1943@2|Bacteria,46XEX@74201|Verrucomicrobia,3K9MH@414999|Opitutae	414999|Opitutae	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	-
DTH3_k127_6631408_2	497964.CfE428DRAFT_2982	3.718e-67	239.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH3_k127_6631408_0	243090.RB7928	3.31e-153	521.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,2IY76@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RDD
DTH3_k127_6631408_5	382464.ABSI01000005_gene1380	1.53e-10	72.0	2B7DQ@1|root,320HD@2|Bacteria,46XRQ@74201|Verrucomicrobia,2IWFK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6631408_4	998088.B565_2515	9.926e-31	126.0	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,1RU3S@1236|Gammaproteobacteria,1Y501@135624|Aeromonadales	135624|Aeromonadales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
DTH3_k127_6631408_3	398512.JQKC01000004_gene5249	1.715e-58	217.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH3_k127_6631614_0	1123242.JH636435_gene772	1.56e-161	516.0	COG0477@1|root,COG2814@2|Bacteria,2J4VW@203682|Planctomycetes	1123242.JH636435_gene772|-	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6631614_1	1123242.JH636434_gene3154	4.862e-126	413.0	COG2159@1|root,COG2159@2|Bacteria,2J3RZ@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH3_k127_6631614_2	861299.J421_5653	9.316e-114	389.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_6631614_3	1123242.JH636435_gene769	3.376e-78	275.0	2DBNR@1|root,2ZA54@2|Bacteria,2IYX9@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
DTH3_k127_6631614_4	641524.ADICYQ_4752	4.557e-16	88.0	COG1572@1|root,COG1572@2|Bacteria,4NVTK@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
DTH3_k127_6638551_3	243231.GSU2683	1.174e-69	246.0	COG1893@1|root,COG1893@2|Bacteria,1RFSW@1224|Proteobacteria,43AIX@68525|delta/epsilon subdivisions,2X5Z6@28221|Deltaproteobacteria,43T9T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2643	ApbA,ApbA_C
DTH3_k127_6638551_4	330214.NIDE4047	2.482e-27	114.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DTH3_k127_6638551_1	452637.Oter_2651	7.425e-104	348.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH3_k127_6638551_0	278957.ABEA03000112_gene1387	1.039e-152	488.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,3K7B2@414999|Opitutae	414999|Opitutae	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
DTH3_k127_6638551_2	330214.NIDE4374	7.797e-78	269.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DTH3_k127_6638551_5	497964.CfE428DRAFT_2267	4.315e-23	101.0	COG0008@1|root,COG0008@2|Bacteria,46SQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
DTH3_k127_6653071_2	756272.Plabr_2090	4.123e-78	269.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
DTH3_k127_6653071_3	269799.Gmet_2576	1.239e-30	127.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,42SDV@68525|delta/epsilon subdivisions,2WPXR@28221|Deltaproteobacteria,43T4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH3_k127_6653071_1	497964.CfE428DRAFT_4282	1.411e-151	484.0	COG1013@1|root,COG1013@2|Bacteria,46SRY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DTH3_k127_6653071_0	497964.CfE428DRAFT_4284	3.198e-259	812.0	COG0674@1|root,COG0674@2|Bacteria,46SM9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DTH3_k127_6653071_4	497964.CfE428DRAFT_4443	1.201e-29	124.0	COG0561@1|root,COG0561@2|Bacteria,46SWT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
DTH3_k127_6660891_2	546266.NEIMUCOT_06302	4.776e-68	243.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,2KQN6@206351|Neisseriales	206351|Neisseriales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH3_k127_6660891_0	1396141.BATP01000020_gene50	1.457e-213	706.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_6660891_1	243231.GSU3381	3.267e-188	607.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,43TFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH3_k127_6660891_3	941449.dsx2_3419	7.314e-43	161.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,2M8QZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM tRNA synthetase class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DTH3_k127_6676342_2	234267.Acid_3103	1.063e-20	93.0	COG4948@1|root,COG4948@2|Bacteria,3Y46A@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
DTH3_k127_6676342_0	641524.ADICYQ_2925	3.302e-143	462.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_6676342_3	247490.KSU1_D0417	1.689e-14	74.0	COG1052@1|root,COG1052@2|Bacteria,2IWTC@203682|Planctomycetes	203682|Planctomycetes	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DTH3_k127_6676342_1	471854.Dfer_1899	2.419e-99	332.0	COG4409@1|root,COG4409@2|Bacteria,4NKEW@976|Bacteroidetes,47U77@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_6682572_1	497964.CfE428DRAFT_2622	1.261e-127	414.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DTH3_k127_6682572_0	880070.Cycma_3617	8.355e-128	431.0	2DBT1@1|root,2ZAV2@2|Bacteria,4NK57@976|Bacteroidetes,47XPG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6682572_2	316274.Haur_4435	2.427e-13	71.0	COG0451@1|root,COG0451@2|Bacteria,2G6S4@200795|Chloroflexi,374RT@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DTH3_k127_6683655_1	1157708.KB907454_gene2941	3.193e-10	71.0	COG4447@1|root,COG4886@1|root,COG4447@2|Bacteria,COG4886@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6683655_0	324602.Caur_0299	4.786e-16	89.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
DTH3_k127_6683655_2	1121116.KB894765_gene643	0.0002548	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,4AAY1@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
DTH3_k127_6686128_2	1123073.KB899241_gene3060	5.157e-90	303.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XDA0@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08137	-	-	-	-	ko00000,ko02000	2.A.1.1.1	-	-	Sugar_tr
DTH3_k127_6686128_1	1499967.BAYZ01000164_gene6663	9.252e-151	491.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH3_k127_6686128_0	497964.CfE428DRAFT_3605	6.003e-167	539.0	COG0364@1|root,COG0364@2|Bacteria,46SHX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
DTH3_k127_6686128_3	378806.STAUR_7040	1.986e-26	118.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
DTH3_k127_6692167_0	1123242.JH636434_gene4307	9.023e-69	240.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH3_k127_6692167_2	1191523.MROS_0856	9.244e-57	203.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
DTH3_k127_6692167_4	1283283.ATXA01000005_gene2190	6.493e-05	48.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESQP@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
DTH3_k127_6692167_3	1123242.JH636434_gene4667	1.912e-44	176.0	2F56K@1|root,33XTB@2|Bacteria,2J30K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6692167_1	861299.J421_4478	1.601e-66	233.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DTH3_k127_6693919_1	903818.KI912268_gene1954	1.043e-114	373.0	COG4581@1|root,COG4581@2|Bacteria	2|Bacteria	L	dead DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
DTH3_k127_6693919_0	768710.DesyoDRAFT_1775	5.024e-133	445.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
DTH3_k127_6694593_3	292459.STH496	4.881e-28	119.0	COG1051@1|root,COG1051@2|Bacteria,1VHQV@1239|Firmicutes,24SJS@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH3_k127_6694593_4	660470.Theba_0471	0.0003775	52.0	COG0477@1|root,COG2814@2|Bacteria,2GC2Q@200918|Thermotogae	200918|Thermotogae	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_6694593_1	1382359.JIAL01000001_gene1578	1.597e-90	304.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH3_k127_6694593_0	649638.Trad_2886	9.31e-160	519.0	COG1057@1|root,COG1057@2|Bacteria	2|Bacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	CTP_transf_like
DTH3_k127_6694593_2	1123242.JH636438_gene5875	9.769e-47	173.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_6696526_0	497964.CfE428DRAFT_3817	3.858e-155	497.0	COG1690@1|root,COG1690@2|Bacteria,46SU0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
DTH3_k127_669707_0	1122931.AUAE01000028_gene155	2.472e-88	323.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_669707_3	349741.Amuc_1932	4.271e-61	228.0	COG0251@1|root,COG0251@2|Bacteria,46V5Y@74201|Verrucomicrobia,2IW47@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
DTH3_k127_669707_1	697281.Mahau_2725	6.559e-88	302.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,42IQ4@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_669707_2	903818.KI912269_gene107	2.865e-66	235.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
DTH3_k127_6721692_3	247490.KSU1_A0075	1.064e-29	119.0	COG0543@1|root,COG0543@2|Bacteria,2IYBB@203682|Planctomycetes	203682|Planctomycetes	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DTH3_k127_6721692_1	518766.Rmar_2589	2.588e-100	338.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
DTH3_k127_6721692_0	518766.Rmar_2590	3.286e-173	554.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
DTH3_k127_6721692_4	1172180.KB911792_gene3761	1.269e-15	83.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
DTH3_k127_6721692_2	768671.ThimaDRAFT_4573	2.947e-48	190.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,1T9ZT@1236|Gammaproteobacteria,1WYMB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
DTH3_k127_6726162_5	1158338.JNLJ01000001_gene244	1.176e-19	89.0	COG1127@1|root,COG1127@2|Bacteria,2G3XY@200783|Aquificae	200783|Aquificae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH3_k127_6726162_4	1123371.ATXH01000005_gene2035	5.735e-35	146.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH3_k127_6726162_0	709986.Deima_0518	1.529e-153	505.0	COG1092@1|root,COG1092@2|Bacteria,1WK2R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DTH3_k127_6726162_1	1254432.SCE1572_02560	1.488e-139	457.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DTH3_k127_6726162_6	1096930.L284_00460	4.083e-05	55.0	COG5349@1|root,COG5349@2|Bacteria,1N0PN@1224|Proteobacteria,2UBSH@28211|Alphaproteobacteria,2K5S3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
DTH3_k127_6726162_2	1267534.KB906755_gene4489	3.631e-87	301.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH3_k127_6726162_3	595460.RRSWK_00638	7.969e-65	226.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2IWZA@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,ABC_tran
DTH3_k127_6732616_1	861299.J421_1753	1.814e-138	458.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH3_k127_6732616_0	1121346.KB899817_gene3149	2.84e-296	923.0	COG0129@1|root,COG0129@2|Bacteria,1U56J@1239|Firmicutes,4HD31@91061|Bacilli,26U7U@186822|Paenibacillaceae	91061|Bacilli	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
DTH3_k127_6732616_2	530564.Psta_0399	1.865e-82	284.0	COG3970@1|root,COG3970@2|Bacteria,2IWUC@203682|Planctomycetes	203682|Planctomycetes	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
DTH3_k127_6732616_3	1288963.ADIS_1952	2.415e-14	78.0	COG3509@1|root,COG3509@2|Bacteria,4NJNR@976|Bacteroidetes,47UWE@768503|Cytophagia	976|Bacteroidetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6737949_2	740709.A10D4_00975	3.737e-05	50.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
DTH3_k127_6737949_1	1121957.ATVL01000014_gene1459	1.005e-11	70.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6737949_0	497964.CfE428DRAFT_4660	5.739e-157	506.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_6751221_1	497964.CfE428DRAFT_6083	8.231e-62	221.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
DTH3_k127_6751221_2	1191523.MROS_2770	1.134e-32	135.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
DTH3_k127_6751221_0	583355.Caka_1555	1.077e-99	341.0	COG2217@1|root,COG2217@2|Bacteria,46S53@74201|Verrucomicrobia,3K7EF@414999|Opitutae	414999|Opitutae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
DTH3_k127_677923_1	1173028.ANKO01000193_gene5879	1.169e-166	529.0	COG0451@1|root,COG0451@2|Bacteria,1G3T6@1117|Cyanobacteria,1HA43@1150|Oscillatoriales	1117|Cyanobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DTH3_k127_677923_0	1173028.ANKO01000193_gene5880	1.761e-207	669.0	COG2303@1|root,COG2303@2|Bacteria,1G3V7@1117|Cyanobacteria,1H9T9@1150|Oscillatoriales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
DTH3_k127_677923_5	1173028.ANKO01000193_gene5881	1.937e-17	97.0	2DJZT@1|root,32UE2@2|Bacteria,1G8K4@1117|Cyanobacteria,1HCD2@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_677923_2	649638.Trad_2705	6.902e-147	483.0	COG0382@1|root,COG0546@1|root,COG0382@2|Bacteria,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,UbiA
DTH3_k127_677923_6	158787.BSCA_0674	8.644e-05	55.0	COG5305@1|root,COG5305@2|Bacteria,2HZBN@201174|Actinobacteria,4CZKJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DTH3_k127_677923_4	497964.CfE428DRAFT_2614	6.378e-51	186.0	COG4989@1|root,COG4989@2|Bacteria,46SU2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DTH3_k127_6785980_1	497964.CfE428DRAFT_5946	4.243e-41	161.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_6785980_0	243233.MCA2756	7.036e-158	505.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
DTH3_k127_6786033_0	1123242.JH636434_gene4307	1.746e-112	371.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
DTH3_k127_6786033_2	313628.LNTAR_18430	2.138e-28	120.0	COG1372@1|root,COG1372@2|Bacteria	2|Bacteria	L	intein-mediated protein splicing	-	-	1.1.98.6,3.6.3.14,3.6.3.15,4.1.1.35	ko:K02117,ko:K08678,ko:K21636	ko00190,ko00230,ko00240,ko00520,ko01100,map00190,map00230,map00240,map00520,map01100	M00053,M00159,M00361	R01384,R11633,R11634,R11635,R11636	RC00508,RC00613	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-cone,DUF4280,Intein_splicing,LAGLIDADG_3,NRDD,PT-HINT
DTH3_k127_6786033_1	765420.OSCT_3130	2.06e-67	245.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
DTH3_k127_6786033_4	113355.CM001775_gene3666	1.874e-13	76.0	COG1404@1|root,COG1404@2|Bacteria,1G1G8@1117|Cyanobacteria	1117|Cyanobacteria	O	Subtilisin-like serine protease	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DTH3_k127_6790969_0	247490.KSU1_D0577	2.004e-192	612.0	COG0243@1|root,COG0243@2|Bacteria,2J2QN@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin
DTH3_k127_6790969_1	1379698.RBG1_1C00001G0011	2.35e-125	419.0	COG2010@1|root,COG2180@1|root,COG2010@2|Bacteria,COG2180@2|Bacteria,2NR8D@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K00405,ko:K17052	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko02000	3.D.4.3,5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
DTH3_k127_6790969_2	452637.Oter_0906	2.875e-09	59.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH3_k127_6795572_2	452637.Oter_2685	2.77e-112	366.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,3K7UQ@414999|Opitutae	414999|Opitutae	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DTH3_k127_6795572_8	1403819.BATR01000042_gene1260	2.485e-10	67.0	COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N,T2SSG
DTH3_k127_6795572_4	1121472.AQWN01000011_gene1202	5.006e-54	204.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,263U1@186807|Peptococcaceae	186801|Clostridia	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
DTH3_k127_6795572_5	1123070.KB899253_gene998	1.621e-53	199.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,2IUD8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NAD_kinase
DTH3_k127_6795572_3	667014.Thein_0763	2.67e-74	258.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
DTH3_k127_6795572_6	497964.CfE428DRAFT_5639	1.367e-12	74.0	COG0745@1|root,COG0745@2|Bacteria	497964.CfE428DRAFT_5639|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6795572_0	56780.SYN_00126	1.681e-157	505.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH3_k127_6795572_1	1304888.ATWF01000001_gene1852	1.966e-128	420.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH3_k127_6795572_7	251229.Chro_0968	2.257e-11	67.0	COG1565@1|root,COG1565@2|Bacteria,1G16Z@1117|Cyanobacteria,3VI99@52604|Pleurocapsales	1117|Cyanobacteria	S	acr, cog1565	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
DTH3_k127_6814068_5	1288494.EBAPG3_24600	3.592e-07	53.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,2W0HU@28216|Betaproteobacteria,373ZH@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
DTH3_k127_6814068_1	1122236.KB905142_gene569	1.202e-148	479.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KKVC@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
DTH3_k127_6814068_4	640081.Dsui_0260	6.626e-112	370.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KV4D@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
DTH3_k127_6814068_3	1121035.AUCH01000001_gene1959	1.902e-123	404.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,2KV49@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysW	-	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
DTH3_k127_6814068_2	330214.NIDE1620	6.369e-136	441.0	COG1118@1|root,COG1118@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25,3.6.3.29	ko:K02017,ko:K02045,ko:K10112,ko:K16787	ko00920,ko02010,map00920,map02010	M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00582,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE,TOBE_3
DTH3_k127_6814068_0	234267.Acid_2664	3.808e-201	638.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
DTH3_k127_6820209_3	497964.CfE428DRAFT_2982	3.202e-55	201.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH3_k127_6820209_2	497964.CfE428DRAFT_0066	3.304e-71	265.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
DTH3_k127_6820209_5	153948.NAL212_2874	1.397e-12	81.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,371Z5@32003|Nitrosomonadales	28216|Betaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
DTH3_k127_6820209_7	1089545.KB913037_gene8403	4.086e-08	66.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2HSAI@201174|Actinobacteria,4ED2E@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6820209_4	1218084.BBJK01000086_gene5778	1.15e-25	123.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
DTH3_k127_6820209_0	1396141.BATP01000060_gene4727	2.499e-224	739.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
DTH3_k127_6820209_1	443143.GM18_2869	3.982e-78	265.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH3_k127_6820209_6	1396418.BATQ01000007_gene1428	4.479e-09	67.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46VHK@74201|Verrucomicrobia,2IW1Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH3_k127_6822916_0	316274.Haur_4856	1.42e-11	78.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
DTH3_k127_6832952_2	1123242.JH636434_gene4287	1.043e-58	233.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_6832952_1	1403819.BATR01000125_gene4449	1.468e-92	340.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH3_k127_6832952_0	1121904.ARBP01000012_gene1301	7.917e-102	368.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,47MUQ@768503|Cytophagia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6855260_0	714943.Mucpa_3835	2.341e-206	665.0	COG3534@1|root,COG3534@2|Bacteria,4NH8M@976|Bacteroidetes,1IVFD@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C
DTH3_k127_6855260_1	1121904.ARBP01000038_gene2561	8.353e-120	392.0	COG2382@1|root,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,47JIQ@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Glyco_hydro_10
DTH3_k127_6864775_2	1120966.AUBU01000002_gene1998	1.245e-05	54.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6864775_0	530564.Psta_1668	1.505e-129	429.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_6864775_1	575540.Isop_0616	2.65e-68	247.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
DTH3_k127_6870545_1	1123008.KB905692_gene41	2.913e-37	149.0	2CKYD@1|root,32SD9@2|Bacteria,4NUH2@976|Bacteroidetes,2FYD6@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6870545_0	471854.Dfer_1841	7.519e-161	527.0	28MSE@1|root,2ZB0T@2|Bacteria,4NU38@976|Bacteroidetes	976|Bacteroidetes	S	Endo-alpha-N-acetylgalactosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_101
DTH3_k127_6885650_2	1121447.JONL01000009_gene2551	2.594e-111	377.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2M8H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
DTH3_k127_6885650_0	340177.Cag_1407	1.512e-208	671.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH3_k127_6885650_1	340177.Cag_1408	3.213e-127	430.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
DTH3_k127_6885650_5	118005.AWNK01000004_gene1113	3.985e-19	96.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH3_k127_6885650_3	340177.Cag_0615	7.985e-63	241.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
DTH3_k127_6885650_4	316067.Geob_3308	1.124e-46	184.0	COG2373@1|root,COG3291@1|root,COG5276@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,COG5276@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
DTH3_k127_6923492_0	373994.Riv7116_5117	7.568e-86	324.0	COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria,1HIHD@1161|Nostocales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Cadherin,Calx-beta,DUF4347,HemolysinCabind,Lectin_C,P_proprotein,Peptidase_S8,VWA
DTH3_k127_6923492_3	1190603.AJYD01000022_gene371	1.125e-26	128.0	COG3391@1|root,COG3391@2|Bacteria,1MX9P@1224|Proteobacteria,1RQU8@1236|Gammaproteobacteria,1XTSY@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4842)	VPA1172	-	-	-	-	-	-	-	-	-	-	-	DUF4842
DTH3_k127_6923492_4	266779.Meso_2414	4.905e-24	120.0	COG1361@1|root,COG1361@2|Bacteria,1R5G4@1224|Proteobacteria,2UC86@28211|Alphaproteobacteria,43MTR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DTH3_k127_6923492_1	96561.Dole_1791	9.08e-84	312.0	COG1044@1|root,COG1361@1|root,COG1653@1|root,COG1044@2|Bacteria,COG1361@2|Bacteria,COG1653@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6923492_2	378806.STAUR_2903	1.181e-55	223.0	COG3291@1|root,COG4257@1|root,COG3291@2|Bacteria,COG4257@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
DTH3_k127_696091_0	1232453.BAIF02000004_gene1569	1.783e-165	533.0	28MXM@1|root,2Z8AT@2|Bacteria,1V0XI@1239|Firmicutes,24DIS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_696091_3	1158294.JOMI01000004_gene3492	8.445e-15	81.0	COG4030@1|root,COG4030@2|Bacteria,4NIPI@976|Bacteroidetes,2FRFX@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
DTH3_k127_696091_1	1267535.KB906767_gene5231	3.279e-95	331.0	COG3934@1|root,COG3934@2|Bacteria,3Y387@57723|Acidobacteria,2JJ00@204432|Acidobacteriia	204432|Acidobacteriia	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH3_k127_696091_2	886293.Sinac_0949	1.639e-39	165.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
DTH3_k127_6970561_1	497964.CfE428DRAFT_3740	1.825e-15	77.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_6970561_0	448385.sce0471	7.475e-109	364.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
DTH3_k127_6979206_2	395493.BegalDRAFT_2362	2.344e-94	322.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,461AE@72273|Thiotrichales	72273|Thiotrichales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
DTH3_k127_6979206_5	1254432.SCE1572_38305	2.165e-17	91.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	pp2c12	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
DTH3_k127_6979206_3	452637.Oter_3080	1.445e-68	244.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
DTH3_k127_6979206_4	1121033.AUCF01000020_gene699	9.132e-39	154.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yqfZ	-	-	-	-	-	-	-	-	-	-	-	LysM
DTH3_k127_6979206_1	118168.MC7420_3120	6.747e-128	432.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H72F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
DTH3_k127_6979206_0	330214.NIDE0551	8.087e-166	550.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
DTH3_k127_6979206_6	756272.Plabr_1895	5.292e-16	87.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_6979206_7	682795.AciX8_3725	9.4e-11	75.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
DTH3_k127_6981568_0	497964.CfE428DRAFT_3562	5.337e-129	424.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DTH3_k127_6981568_5	481448.Minf_0089	6.538e-16	91.0	2ADRD@1|root,313GQ@2|Bacteria,46ZIR@74201|Verrucomicrobia,37GDJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
DTH3_k127_6981568_4	497964.CfE428DRAFT_4116	6.668e-19	95.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH3_k127_6981568_6	889378.Spiaf_1653	4.312e-15	79.0	2EH48@1|root,33AW7@2|Bacteria,2J921@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_6981568_1	1267533.KB906738_gene2187	1.162e-57	204.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DTH3_k127_6981568_3	1267533.KB906738_gene2186	1.061e-23	103.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
DTH3_k127_6986482_3	1267535.KB906767_gene4403	2.693e-11	76.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
DTH3_k127_6986482_2	382464.ABSI01000013_gene1863	8.094e-15	88.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH3_k127_6986482_5	46234.ANA_C10684	5.947e-06	51.0	COG2026@1|root,COG2026@2|Bacteria,1GA93@1117|Cyanobacteria,1HT80@1161|Nostocales	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
DTH3_k127_6986482_4	42565.FP66_10530	4.905e-07	61.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
DTH3_k127_6986482_0	1313421.JHBV01000041_gene3629	5.337e-186	609.0	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
DTH3_k127_6986482_1	1304885.AUEY01000096_gene2839	1.476e-63	223.0	COG1404@1|root,COG2304@1|root,COG2911@1|root,COG3897@1|root,COG5434@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3897@2|Bacteria,COG5434@2|Bacteria,1P8N9@1224|Proteobacteria,43DXZ@68525|delta/epsilon subdivisions,2X72D@28221|Deltaproteobacteria,2MNHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
DTH3_k127_7003172_1	316067.Geob_3008	6.186e-90	308.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,43TMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
DTH3_k127_7003172_2	452637.Oter_2645	1.262e-73	257.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,3K83I@414999|Opitutae	414999|Opitutae	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
DTH3_k127_7003172_4	592028.GCWU000321_00198	1.281e-40	161.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
DTH3_k127_7003172_3	1396141.BATP01000058_gene1952	4.333e-44	172.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
DTH3_k127_7003172_0	497964.CfE428DRAFT_2029	9.753e-101	338.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DTH3_k127_7003172_5	1156937.MFUM_930026	9.993e-37	149.0	COG4137@1|root,COG4137@2|Bacteria,46T0T@74201|Verrucomicrobia,37GN8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DTH3_k127_7003172_6	1403819.BATR01000088_gene2595	2.972e-35	141.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,2IU0T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Glutamyl-tRNAGlu reductase, N-terminal domain	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
DTH3_k127_7010497_1	927658.AJUM01000034_gene376	1.737e-39	171.0	COG2133@1|root,COG2312@1|root,COG5563@1|root,COG2133@2|Bacteria,COG2312@2|Bacteria,COG5563@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Fn3_assoc,LTD
DTH3_k127_7010497_3	1349767.GJA_2351	1.993e-05	59.0	COG3250@1|root,COG3250@2|Bacteria,1R31K@1224|Proteobacteria	2|Bacteria	G	Beta-1,3-glucanase	glcI	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_64,Ricin_B_lectin
DTH3_k127_7010497_2	1396141.BATP01000007_gene5656	1.84e-23	119.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7010497_0	382464.ABSI01000005_gene1189	8.111e-71	274.0	COG2312@1|root,COG5337@1|root,COG2312@2|Bacteria,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_7014295_3	530564.Psta_1167	2.181e-107	356.0	COG3119@1|root,COG3119@2|Bacteria	530564.Psta_1167|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7014295_0	521674.Plim_3713	1.493e-258	806.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Glyco_hydro_28
DTH3_k127_7014295_2	1123073.KB899241_gene3085	4.596e-123	425.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Big_2,Big_4,F5_F8_type_C,Glyco_hydro_16,Inhibitor_I9,PA,Peptidase_S8,SLH
DTH3_k127_7014295_5	391735.Veis_0534	4.92e-07	63.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VJM2@28216|Betaproteobacteria,4A9PV@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH3_k127_7014295_4	530564.Psta_4257	1.545e-71	255.0	COG2755@1|root,COG5306@1|root,COG2755@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
DTH3_k127_7014295_1	1385935.N836_16125	4.841e-124	412.0	COG5434@1|root,COG5434@2|Bacteria,1GC14@1117|Cyanobacteria,1HF7U@1150|Oscillatoriales	1117|Cyanobacteria	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
DTH3_k127_7032612_1	1396141.BATP01000032_gene4324	5.012e-86	295.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH3_k127_7032612_3	1396141.BATP01000032_gene4325	2.214e-53	199.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7032612_2	452637.Oter_0820	9.39e-84	284.0	COG0012@1|root,COG0012@2|Bacteria	2|Bacteria	J	GTP binding	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DTH3_k127_7032612_0	886293.Sinac_2716	1.833e-96	325.0	COG1477@1|root,COG1477@2|Bacteria,2IY0F@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DTH3_k127_7035203_4	686340.Metal_0410	4.458e-09	62.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1XGTV@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
DTH3_k127_7035203_2	205918.Psyr_0855	9.424e-21	105.0	28IQ1@1|root,2Z8PV@2|Bacteria,1NYS1@1224|Proteobacteria,1RPR2@1236|Gammaproteobacteria,1Z57B@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	-	-	IV02_13120	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7035203_0	177439.DP2558	8.955e-81	301.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K07459,ko:K10110	ko02010,map02010	M00194,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22,3.A.1.2	-	-	AAA_11,AAA_12,AAA_13,AAA_23
DTH3_k127_7035203_1	177439.DP2557	8.509e-35	145.0	2EVII@1|root,33NYR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7035203_3	215803.DB30_8367	1.265e-11	64.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,4345U@68525|delta/epsilon subdivisions,2X20T@28221|Deltaproteobacteria,2YVEZ@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS
DTH3_k127_7042856_0	794903.OPIT5_07190	1.613e-182	591.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,46URZ@74201|Verrucomicrobia,3K946@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
DTH3_k127_7058546_1	309807.SRU_1452	1.494e-27	124.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7058546_0	1173026.Glo7428_2698	3.105e-118	412.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH3_k127_7067775_1	378806.STAUR_1759	2.728e-12	81.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
DTH3_k127_7067775_0	1123279.ATUS01000001_gene2474	9.35e-13	71.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RPNH@1236|Gammaproteobacteria,1JBYT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	qseB	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
DTH3_k127_7097732_1	272134.KB731324_gene5167	9.622e-48	182.0	COG4671@1|root,COG4671@2|Bacteria,1G0X1@1117|Cyanobacteria,1H7SA@1150|Oscillatoriales	1117|Cyanobacteria	S	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
DTH3_k127_7097732_0	380358.XALC_0037	7.026e-158	511.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,1RP70@1236|Gammaproteobacteria,1X56Y@135614|Xanthomonadales	135614|Xanthomonadales	G	Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
DTH3_k127_7097732_2	530564.Psta_2822	2.092e-13	72.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_7099703_0	452637.Oter_0670	1.018e-181	574.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DTH3_k127_7099703_1	452637.Oter_0669	1.082e-118	385.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
DTH3_k127_7099703_2	314230.DSM3645_14155	0.0003438	43.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DTH3_k127_7100988_1	1121033.AUCF01000020_gene665	1.453e-38	162.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1QUUN@1224|Proteobacteria,2TX9V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Outer membrane autotransporter	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH3_k127_7100988_3	443143.GM18_2869	1.123e-09	61.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH3_k127_7100988_2	1158292.JPOE01000002_gene3555	6.695e-25	107.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH3_k127_7100988_0	240016.ABIZ01000001_gene1588	2.84e-51	198.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_7103462_7	1131269.AQVV01000050_gene416	5.157e-11	68.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	hlpA	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH3_k127_7103462_0	497964.CfE428DRAFT_6478	5.003e-187	593.0	COG1453@1|root,COG1453@2|Bacteria,46S6J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
DTH3_k127_7103462_5	497964.CfE428DRAFT_6673	8.788e-27	112.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH3_k127_7103462_2	1288963.ADIS_2835	3.35e-131	435.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH3_k127_7103462_1	478741.JAFS01000001_gene1976	1.621e-145	470.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
DTH3_k127_7103462_4	794903.OPIT5_06500	4.305e-33	141.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
DTH3_k127_7103462_3	1163617.SCD_n02152	7.811e-60	211.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
DTH3_k127_7112728_2	435832.HMPREF0604_01422	6.486e-21	95.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
DTH3_k127_7112728_1	861299.J421_5600	1.999e-94	321.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
DTH3_k127_7112728_0	861299.J421_5609	2.297e-115	380.0	COG1879@1|root,COG1879@2|Bacteria,1ZV3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
DTH3_k127_7112728_3	1150469.RSPPHO_02781	0.0005539	47.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7115974_0	1122603.ATVI01000006_gene308	8.97e-55	220.0	COG0515@1|root,COG3710@1|root,COG0515@2|Bacteria,COG3710@2|Bacteria,1R52Q@1224|Proteobacteria,1RQY5@1236|Gammaproteobacteria,1XCCX@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,Trans_reg_C
DTH3_k127_7115974_1	66874.JOFS01000006_gene4504	3.475e-44	186.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
DTH3_k127_711852_2	1089547.KB913013_gene2067	3.885e-15	76.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,47MKW@768503|Cytophagia	976|Bacteroidetes	E	Dipeptidyl peptidase IV	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
DTH3_k127_711852_0	1123508.JH636445_gene6824	9.216e-215	682.0	COG4805@1|root,COG4805@2|Bacteria,2IXQZ@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DTH3_k127_711852_1	240016.ABIZ01000001_gene4797	8.308e-127	417.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DTH3_k127_7128273_1	452637.Oter_0618	2.457e-80	272.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH3_k127_7128273_0	497964.CfE428DRAFT_6510	6.966e-135	443.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
DTH3_k127_7128273_2	452637.Oter_1638	3.74e-45	166.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,3K7NZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_713080_3	1173023.KE650771_gene983	0.0001803	47.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
DTH3_k127_713080_0	472759.Nhal_1554	4.909e-139	457.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1X0HU@135613|Chromatiales	135613|Chromatiales	S	PFAM Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_713080_1	221288.JH992901_gene3760	3.405e-68	237.0	COG1247@1|root,COG1247@2|Bacteria,1G8E2@1117|Cyanobacteria	1117|Cyanobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
DTH3_k127_713080_2	497964.CfE428DRAFT_4864	8.225e-23	102.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7133512_3	452637.Oter_3202	0.0002274	44.0	COG1869@1|root,COG1869@2|Bacteria,46VR5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	RbsD / FucU transport protein family	-	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
DTH3_k127_7133512_2	661478.OP10G_1142	8.907e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_7133512_1	1122165.AUHS01000023_gene237	1.046e-65	241.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RXSU@1236|Gammaproteobacteria,1JDJP@118969|Legionellales	118969|Legionellales	M	lipid A biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
DTH3_k127_7133512_0	272624.lpg0362	1.228e-82	286.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JD6F@118969|Legionellales	118969|Legionellales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DTH3_k127_7137693_0	1403819.BATR01000135_gene4816	2.299e-245	764.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
DTH3_k127_7137693_1	234267.Acid_7032	3.285e-105	356.0	COG2271@1|root,COG2271@2|Bacteria,3Y3FW@57723|Acidobacteria	57723|Acidobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_7149149_0	926550.CLDAP_09870	8.221e-153	495.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
DTH3_k127_7149149_1	1347392.CCEZ01000010_gene2401	8.406e-47	181.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,36EZ7@31979|Clostridiaceae	186801|Clostridia	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DTH3_k127_7149149_2	1499967.BAYZ01000073_gene2050	2.544e-07	57.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD,HAD_2,Hydrolase,Hydrolase_like
DTH3_k127_7154024_0	1173027.Mic7113_2682	8.15e-221	709.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
DTH3_k127_7154024_2	1173027.Mic7113_2682	1.212e-23	111.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
DTH3_k127_7154024_3	314345.SPV1_00987	1.062e-07	60.0	2DPGY@1|root,3320R@2|Bacteria,1ND7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
DTH3_k127_7154024_1	1123393.KB891317_gene2207	3.745e-104	346.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VQ9J@28216|Betaproteobacteria,1KSDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
DTH3_k127_7154024_4	452637.Oter_1161	7.509e-07	53.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
DTH3_k127_7186485_0	497964.CfE428DRAFT_5395	2.533e-160	514.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH3_k127_7186485_4	1396418.BATQ01000003_gene1334	4.727e-12	74.0	COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia,2IUR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
DTH3_k127_7186485_1	481448.Minf_0919	5.412e-40	156.0	COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia,37GG9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DTH3_k127_7186485_5	382464.ABSI01000010_gene3336	1.885e-09	69.0	COG3064@1|root,COG3064@2|Bacteria,46VZ5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7186485_2	456442.Mboo_0115	2.612e-22	110.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
DTH3_k127_7186485_3	215803.DB30_6944	1.356e-14	75.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2X2JP@28221|Deltaproteobacteria,2YY11@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
DTH3_k127_7187735_5	638303.Thal_1379	6.833e-30	120.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DTH3_k127_7187735_7	497964.CfE428DRAFT_3331	1.146e-25	109.0	COG1135@1|root,COG1135@2|Bacteria,46WAD@74201|Verrucomicrobia	74201|Verrucomicrobia	P	NIL domain	-	-	-	-	-	-	-	-	-	-	-	-	NIL
DTH3_k127_7187735_8	478741.JAFS01000002_gene623	1.781e-22	101.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,37GUN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
DTH3_k127_7187735_1	497964.CfE428DRAFT_4489	4.154e-229	718.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
DTH3_k127_7187735_3	497964.CfE428DRAFT_4490	7.007e-92	310.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DTH3_k127_7187735_0	497964.CfE428DRAFT_4491	1.55e-251	783.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DTH3_k127_7187735_6	1403819.BATR01000049_gene1414	3.351e-27	116.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DTH3_k127_7187735_4	497964.CfE428DRAFT_4493	4.883e-44	166.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
DTH3_k127_7187735_10	497964.CfE428DRAFT_4494	5.125e-18	93.0	2DS8G@1|root,33EZT@2|Bacteria,46T9M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DTH3_k127_7187735_2	497964.CfE428DRAFT_4495	2.091e-110	365.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DTH3_k127_7191014_9	278957.ABEA03000080_gene3213	2.393e-15	78.0	28JIN@1|root,30U02@2|Bacteria,46YTT@74201|Verrucomicrobia,3K7XH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7191014_8	1396141.BATP01000023_gene664	3.192e-17	96.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
DTH3_k127_7191014_10	497964.CfE428DRAFT_5963	5.293e-12	78.0	2F7AY@1|root,33ZS4@2|Bacteria,46VZW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7191014_3	497964.CfE428DRAFT_3022	1.047e-34	136.0	COG2363@1|root,COG2363@2|Bacteria,46T86@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
DTH3_k127_7191014_7	497964.CfE428DRAFT_4380	4.136e-25	113.0	COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH3_k127_7191014_6	497964.CfE428DRAFT_4379	1.275e-26	116.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DTH3_k127_7191014_2	886293.Sinac_3711	2.206e-97	330.0	COG2896@1|root,COG2896@2|Bacteria,2IXWS@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
DTH3_k127_7191014_5	452637.Oter_2046	8.709e-27	118.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia,3K9NW@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
DTH3_k127_7191014_11	1265505.ATUG01000001_gene3561	1.253e-10	68.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
DTH3_k127_7191014_4	1476973.JMMB01000007_gene3240	4.985e-34	145.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
DTH3_k127_7191014_1	497964.CfE428DRAFT_5481	4.819e-164	532.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
DTH3_k127_7191014_0	243233.MCA2161	2.548e-168	553.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7191278_1	344747.PM8797T_06060	1.673e-130	431.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_7191278_3	373994.Riv7116_3284	2.337e-65	235.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	elrF	-	-	-	-	-	-	-	-	-	-	-	Cutinase,DUF1350,DUF1631
DTH3_k127_7191278_5	240016.ABIZ01000001_gene54	1.841e-17	83.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
DTH3_k127_7191278_2	926550.CLDAP_30260	4.313e-98	356.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
DTH3_k127_7191278_0	742725.HMPREF9450_00266	9.574e-301	952.0	COG3408@1|root,COG3408@2|Bacteria,4NJY8@976|Bacteroidetes,2G2N9@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH3_k127_7191278_4	1121481.AUAS01000001_gene4367	3.612e-48	175.0	COG1082@1|root,COG1082@2|Bacteria,4NJF5@976|Bacteroidetes,47MRZ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_719440_0	439235.Dalk_0975	5.787e-119	392.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2MNT3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
DTH3_k127_719440_1	497964.CfE428DRAFT_2661	2.989e-94	315.0	COG1714@1|root,COG1714@2|Bacteria,46UT5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
DTH3_k127_719440_2	794903.OPIT5_23685	1.693e-66	242.0	COG1820@1|root,COG1820@2|Bacteria,46SRF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DTH3_k127_719440_4	1396141.BATP01000036_gene3819	1.385e-13	81.0	2EV5U@1|root,33NKM@2|Bacteria,46WDA@74201|Verrucomicrobia,2IUTJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_719440_3	330214.NIDE3030	3.848e-44	170.0	COG0859@1|root,COG0859@2|Bacteria,3J0KI@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH3_k127_7200715_5	1448139.AI20_18275	5.581e-05	52.0	COG2207@1|root,COG2207@2|Bacteria,1QTTB@1224|Proteobacteria,1T1GI@1236|Gammaproteobacteria,1Y5WC@135624|Aeromonadales	135624|Aeromonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
DTH3_k127_7200715_3	883080.HMPREF9697_03953	4e-25	111.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2VGZ3@28211|Alphaproteobacteria,3JZA4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
DTH3_k127_7200715_4	562970.Btus_3182	8.382e-11	65.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
DTH3_k127_7200715_7	1469607.KK073768_gene4628	0.0004793	45.0	2EHRH@1|root,33BH9@2|Bacteria,1GA8J@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
DTH3_k127_7200715_6	1492922.GY26_17225	0.0003676	45.0	COG2944@1|root,COG2944@2|Bacteria,1NH2C@1224|Proteobacteria,1TBCJ@1236|Gammaproteobacteria,1JBN2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
DTH3_k127_7200715_0	1396141.BATP01000006_gene5432	5.21e-113	392.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
DTH3_k127_7200715_2	167539.Pro_1266	3.215e-34	140.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
DTH3_k127_7200715_1	167539.Pro_1264	8.817e-41	160.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
DTH3_k127_7205352_0	1121904.ARBP01000042_gene4905	3.668e-115	400.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
DTH3_k127_7205352_2	984262.SGRA_1441	1.753e-59	218.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DTH3_k127_7205352_1	497964.CfE428DRAFT_6143	3.106e-62	221.0	COG0163@1|root,COG0163@2|Bacteria,46V9E@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DTH3_k127_7205352_3	497964.CfE428DRAFT_1387	3.445e-38	158.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DTH3_k127_7205352_7	481448.Minf_0708	5.983e-05	53.0	COG2242@1|root,COG2242@2|Bacteria,46WJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH3_k127_7205352_5	1035193.HMPREF9073_01297	6.385e-24	114.0	COG0463@1|root,COG0463@2|Bacteria,4P0ZE@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_7205352_4	344747.PM8797T_29842	1.057e-25	112.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH3_k127_7214154_2	497964.CfE428DRAFT_3556	3.001e-36	139.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DTH3_k127_7214154_1	497964.CfE428DRAFT_3344	3.492e-222	717.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
DTH3_k127_7214154_0	1396418.BATQ01000136_gene3731	9.594e-252	786.0	COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia,2IU2I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
DTH3_k127_7218733_0	1185876.BN8_00481	1.705e-108	372.0	COG2133@1|root,COG3391@1|root,COG3511@1|root,COG2133@2|Bacteria,COG3391@2|Bacteria,COG3511@2|Bacteria,4NEFM@976|Bacteroidetes,47NY3@768503|Cytophagia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
DTH3_k127_7241988_1	452637.Oter_2956	9.267e-79	270.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
DTH3_k127_7241988_0	243090.RB11088	4.04e-200	640.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DTH3_k127_7254710_2	498848.TaqDRAFT_4878	2.029e-27	120.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7254710_3	1100721.ALKO01000032_gene173	4.51e-19	92.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,2VXUM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
DTH3_k127_7254710_1	452637.Oter_4174	2.76e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_7254710_0	452637.Oter_1389	3.888e-145	481.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH3_k127_7273423_0	497964.CfE428DRAFT_3658	4.633e-166	536.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CBM_6,Glyco_hydro_16,Trypsin,VCBS
DTH3_k127_7273423_3	530564.Psta_2414	8.649e-52	186.0	COG0346@1|root,COG0346@2|Bacteria,2J1AZ@203682|Planctomycetes	203682|Planctomycetes	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DTH3_k127_7273423_5	794903.OPIT5_29840	1.429e-23	107.0	2FBS3@1|root,307HF@2|Bacteria,46W7T@74201|Verrucomicrobia,3K85M@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7273423_4	240016.ABIZ01000001_gene3878	2.324e-33	140.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DTH3_k127_7273423_1	1403819.BATR01000112_gene3876	1.167e-79	276.0	COG1082@1|root,COG1082@2|Bacteria,46T96@74201|Verrucomicrobia,2IUNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_7273423_2	1144275.COCOR_06959	8.877e-71	254.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
DTH3_k127_7274516_0	1396141.BATP01000040_gene2082	2.028e-212	713.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH3_k127_7274516_2	1396141.BATP01000060_gene4765	9.322e-28	133.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
DTH3_k127_7274516_1	497964.CfE428DRAFT_2630	2.939e-80	271.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7297200_5	498761.HM1_0138	4.672e-10	72.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
DTH3_k127_7297200_1	1232410.KI421425_gene1538	3.042e-165	541.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
DTH3_k127_7297200_2	1167006.UWK_00360	2.528e-66	237.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
DTH3_k127_7297200_6	228405.HNE_2756	1.277e-06	57.0	COG0322@1|root,COG0322@2|Bacteria,1PVWI@1224|Proteobacteria,2V74B@28211|Alphaproteobacteria,4402D@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	COG0322 Nuclease subunit of the excinuclease complex	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
DTH3_k127_7297200_0	448385.sce4763	5.968e-218	694.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DTH3_k127_7297200_3	313624.NSP_27450	5.534e-52	203.0	COG1075@1|root,COG1075@2|Bacteria,1GIQY@1117|Cyanobacteria,1HP99@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7297217_1	349741.Amuc_1436	3.066e-80	271.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DTH3_k127_7297217_0	1123508.JH636439_gene1065	2.228e-151	486.0	COG0205@1|root,COG0205@2|Bacteria,2IXXF@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DTH3_k127_7300605_2	945713.IALB_0509	1.085e-37	148.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
DTH3_k127_7300605_1	945713.IALB_0510	2.897e-104	349.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
DTH3_k127_7300605_0	385682.AFSL01000102_gene55	3.543e-205	648.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
DTH3_k127_7300605_4	478741.JAFS01000002_gene952	4.18e-06	49.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,37G89@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DTH3_k127_7304751_3	886882.PPSC2_p0627	3.841e-20	94.0	COG3440@1|root,COG3440@2|Bacteria,1V6VD@1239|Firmicutes,4I63P@91061|Bacilli,270GZ@186822|Paenibacillaceae	91061|Bacilli	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7304751_1	555079.Toce_0685	1.054e-96	332.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH3_k127_7304751_2	395493.BegalDRAFT_0545	2.649e-21	99.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
DTH3_k127_7304751_0	118168.MC7420_356	1.331e-278	871.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1H87F@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DTH3_k127_7306142_0	237368.SCABRO_00954	8.047e-192	612.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
DTH3_k127_7306142_2	935866.JAER01000013_gene1035	6.19e-21	108.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CBM_35,F5_F8_type_C,Pectate_lyase_3
DTH3_k127_7306142_1	153721.MYP_3853	7.512e-24	118.0	COG1409@1|root,COG3211@1|root,COG1409@2|Bacteria,COG3211@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH3_k127_7311001_0	404589.Anae109_2915	4.895e-59	211.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7311001_2	983544.Lacal_2171	9.778e-06	56.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I70K@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
DTH3_k127_7311001_1	452637.Oter_2699	5.549e-37	145.0	COG4430@1|root,COG4430@2|Bacteria,46WQC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
DTH3_k127_7312077_0	583355.Caka_2506	1.14e-133	434.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DTH3_k127_7312077_1	1298863.AUEP01000009_gene40	1.586e-14	88.0	COG0681@1|root,COG0681@2|Bacteria,2HES2@201174|Actinobacteria,4DUMF@85009|Propionibacteriales	201174|Actinobacteria	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Peptidase_S24
DTH3_k127_7313692_1	1254432.SCE1572_04430	5.959e-85	285.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,43C30@68525|delta/epsilon subdivisions,2X7DN@28221|Deltaproteobacteria,2YUXV@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
DTH3_k127_7313692_0	448385.sce0660	7.06e-133	450.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
DTH3_k127_7343907_4	411467.BACCAP_01444	2.772e-06	51.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH3_k127_7343907_1	880073.Calab_3423	3.302e-157	515.0	COG3525@1|root,COG3525@2|Bacteria,2NNQC@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
DTH3_k127_7343907_2	402777.KB235903_gene687	1.677e-52	190.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
DTH3_k127_7343907_0	1123508.JH636439_gene1118	2.7e-225	706.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_7343907_5	1408418.JNJH01000059_gene365	0.0002558	53.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,TPR_16,gag-asp_proteas
DTH3_k127_7343907_3	756067.MicvaDRAFT_2865	1.028e-38	152.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DTH3_k127_7346528_4	344747.PM8797T_25701	2.563e-45	169.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH3_k127_7346528_5	1267535.KB906767_gene4834	6.258e-34	146.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
DTH3_k127_7346528_2	344747.PM8797T_24141	2.182e-130	427.0	COG1520@1|root,COG1520@2|Bacteria,2IYK2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_7346528_3	240016.ABIZ01000001_gene2238	1.828e-101	344.0	COG1250@1|root,COG1250@2|Bacteria,46TNQ@74201|Verrucomicrobia,2IWBJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7346528_1	1123508.JH636448_gene7659	4.125e-205	649.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
DTH3_k127_7346528_0	452637.Oter_3479	0.0	1160.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
DTH3_k127_7352372_0	497964.CfE428DRAFT_0809	2.088e-289	913.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7352372_1	555088.DealDRAFT_2373	4.566e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42K3B@68298|Syntrophomonadaceae	186801|Clostridia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_7377860_5	261292.Nit79A3_0430	1.562e-14	81.0	COG1216@1|root,COG2120@1|root,COG1216@2|Bacteria,COG2120@2|Bacteria,1MZSD@1224|Proteobacteria,2VUX2@28216|Betaproteobacteria,3736Y@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_7C,Glycos_transf_2,PIG-L
DTH3_k127_7377860_2	357808.RoseRS_2382	3.89e-62	229.0	COG1216@1|root,COG1216@2|Bacteria,2GB2A@200795|Chloroflexi,377SM@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_7377860_4	489825.LYNGBM3L_21140	1.569e-17	95.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria,1HA1F@1150|Oscillatoriales	2|Bacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc,Glyco_tranf_2_3,Glycos_transf_2
DTH3_k127_7377860_3	56780.SYN_02999	8.409e-21	93.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MRJM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DTH3_k127_7377860_1	395493.BegalDRAFT_2935	9.638e-79	273.0	COG1408@1|root,COG1408@2|Bacteria,1RK37@1224|Proteobacteria,1SEEW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase activity	yaeI	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DTH3_k127_7377860_0	497964.CfE428DRAFT_1577	2.613e-156	502.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
DTH3_k127_7379114_20	756272.Plabr_1201	2.928e-28	128.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
DTH3_k127_7379114_26	545697.HMPREF0216_03070	5.979e-07	61.0	COG1196@1|root,COG1538@1|root,COG3250@1|root,COG1196@2|Bacteria,COG1538@2|Bacteria,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,36F2A@31979|Clostridiaceae	186801|Clostridia	G	family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,FIVAR,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM
DTH3_k127_7379114_2	481448.Minf_0686	4.561e-109	359.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,37FZV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DTH3_k127_7379114_16	794903.OPIT5_02410	2.291e-34	133.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,3K87G@414999|Opitutae	414999|Opitutae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DTH3_k127_7379114_22	497964.CfE428DRAFT_0492	1.696e-23	105.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia	74201|Verrucomicrobia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DTH3_k127_7379114_4	452637.Oter_0220	5.641e-87	298.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DTH3_k127_7379114_11	497964.CfE428DRAFT_0494	4.228e-54	193.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DTH3_k127_7379114_27	349741.Amuc_0295	0.0001022	51.0	COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia,2IUWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L29 protein	-	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DTH3_k127_7379114_21	1403819.BATR01000164_gene5565	1.51e-26	111.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,2IUPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DTH3_k127_7379114_14	1156937.MFUM_870033	8.151e-47	171.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,37GRN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DTH3_k127_7379114_23	382464.ABSI01000011_gene2659	3.926e-23	101.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
DTH3_k127_7379114_8	635013.TherJR_0308	6.692e-60	212.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DTH3_k127_7379114_17	1403819.BATR01000162_gene5349	2.62e-31	124.0	COG0199@1|root,COG0199@2|Bacteria,46TBH@74201|Verrucomicrobia,2IUM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DTH3_k127_7379114_15	265311.Mfl137	3.903e-40	152.0	COG0096@1|root,COG0096@2|Bacteria,3WTD8@544448|Tenericutes	544448|Tenericutes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DTH3_k127_7379114_7	240016.ABIZ01000001_gene4064	1.273e-67	234.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,2IU69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DTH3_k127_7379114_19	771875.Ferpe_1400	1.86e-28	119.0	COG0256@1|root,COG0256@2|Bacteria,2GD32@200918|Thermotogae	200918|Thermotogae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
DTH3_k127_7379114_9	497964.CfE428DRAFT_0503	5.038e-57	205.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DTH3_k127_7379114_13	497964.CfE428DRAFT_0504	2.092e-49	181.0	COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DTH3_k127_7379114_0	452637.Oter_0207	2.821e-151	491.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
DTH3_k127_7379114_5	497964.CfE428DRAFT_0506	4.038e-84	286.0	COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DTH3_k127_7379114_24	1410670.JHXF01000006_gene1255	1.959e-16	81.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3WK1D@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH3_k127_7379114_25	754252.PFREUD_06030	3.528e-12	67.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
DTH3_k127_7379114_12	497964.CfE428DRAFT_0508	1.171e-50	182.0	COG0099@1|root,COG0099@2|Bacteria,46STA@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DTH3_k127_7379114_10	497964.CfE428DRAFT_0509	1.303e-55	200.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DTH3_k127_7379114_6	278957.ABEA03000041_gene2061	1.713e-77	265.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,3K7K0@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DTH3_k127_7379114_1	1396141.BATP01000018_gene1517	2.303e-146	470.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,2ITN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DTH3_k127_7379114_18	1156937.MFUM_1030013	1.676e-30	127.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,37GVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
DTH3_k127_7379114_3	886293.Sinac_5304	1.727e-107	369.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
DTH3_k127_7379114_28	1123242.JH636434_gene5469	0.0001351	46.0	COG2818@1|root,COG2818@2|Bacteria,2IZYU@203682|Planctomycetes	203682|Planctomycetes	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DTH3_k127_7382882_3	530564.Psta_1651	8.578e-13	75.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Peptidase_S9
DTH3_k127_7382882_0	323848.Nmul_A2162	2.928e-48	178.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
DTH3_k127_7382882_1	1283300.ATXB01000001_gene2112	2.389e-46	169.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1T12G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7382882_2	643562.Daes_0072	1.342e-29	123.0	2DQ60@1|root,334WQ@2|Bacteria,1NADI@1224|Proteobacteria,42WP8@68525|delta/epsilon subdivisions,2WRS6@28221|Deltaproteobacteria,2MD9Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
DTH3_k127_7382882_4	391625.PPSIR1_34952	1.654e-07	61.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	FHA,Trans_reg_C,Yop-YscD_cpl
DTH3_k127_7382882_5	251221.35210706	0.0006651	42.0	COG3385@1|root,COG3385@2|Bacteria,1G3D9@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Dimer_Tnp_Tn5,Tnp_DNA_bind
DTH3_k127_7383823_0	1191523.MROS_2035	2.534e-155	501.0	COG0606@1|root,COG0606@2|Bacteria	2|Bacteria	O	chelatase, subunit chli	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DTH3_k127_7383823_6	497964.CfE428DRAFT_6475	4.219e-58	211.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia	2|Bacteria	G	Domain of Unknown Function (DUF1080)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C
DTH3_k127_7383823_1	1396141.BATP01000060_gene4642	4.864e-125	410.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
DTH3_k127_7383823_2	756499.Desde_3002	2.045e-102	346.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DTH3_k127_7383823_3	452637.Oter_0382	1.014e-85	289.0	COG2041@1|root,COG2041@2|Bacteria,46TCM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
DTH3_k127_7383823_5	1123508.JH636443_gene4582	5.391e-65	236.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH3_k127_7383823_4	1384056.N787_01780	1.354e-68	239.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7385359_3	1117319.PSPO_04042	8.546e-05	51.0	2BCPH@1|root,3269T@2|Bacteria,1RJN1@1224|Proteobacteria,1S744@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4824)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4824
DTH3_k127_7385359_0	452637.Oter_4336	7.164e-316	981.0	COG3534@1|root,COG3534@2|Bacteria,46UU3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
DTH3_k127_7385359_1	1340493.JNIF01000003_gene3969	4.345e-177	566.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_7385359_2	1121403.AUCV01000020_gene3110	1.048e-42	160.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
DTH3_k127_7386083_3	278957.ABEA03000046_gene1614	2.1e-68	236.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
DTH3_k127_7386083_0	240016.ABIZ01000001_gene1668	7.811e-157	501.0	COG3239@1|root,COG3239@2|Bacteria,46SX7@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid desaturase	desA	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
DTH3_k127_7386083_6	497964.CfE428DRAFT_6672	2e-22	100.0	COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH3_k127_7386083_4	497964.CfE428DRAFT_6673	2.585e-37	144.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
DTH3_k127_7386083_2	1268635.Loa_01459	6.614e-80	271.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria,1JD7P@118969|Legionellales	118969|Legionellales	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DTH3_k127_7386083_5	56780.SYN_00581	5.818e-32	129.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
DTH3_k127_7386083_7	715451.ambt_02285	9.605e-06	52.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	ppdD	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650,ko:K02682	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
DTH3_k127_7386083_1	1267533.KB906734_gene4022	1.412e-99	337.0	COG0438@1|root,COG0438@2|Bacteria,3Y5K5@57723|Acidobacteria,2JNE3@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7388482_4	97139.C824_01928	6.278e-59	216.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_7388482_3	1499967.BAYZ01000017_gene6249	2.686e-63	231.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_7388482_5	1444309.JAQG01000181_gene3484	6.222e-34	148.0	COG2833@1|root,COG2833@2|Bacteria,1W5BJ@1239|Firmicutes,4I0UF@91061|Bacilli,26VKN@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
DTH3_k127_7388482_6	1303518.CCALI_00378	3e-17	93.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_7388482_1	1396141.BATP01000028_gene2285	2.116e-99	363.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
DTH3_k127_7388482_2	485917.Phep_3119	2.156e-65	234.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NG20@976|Bacteroidetes,1J03Z@117747|Sphingobacteriia	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
DTH3_k127_7388482_0	1121012.AUKX01000016_gene3001	4.011e-183	582.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,1I164@117743|Flavobacteriia,23IAD@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_7400101_0	1403819.BATR01000183_gene6316	5.891e-106	359.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,OMP_b-brl
DTH3_k127_7410778_4	1123368.AUIS01000004_gene217	2.154e-44	167.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,2NCB7@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
DTH3_k127_7410778_2	1121374.KB891580_gene1807	1.611e-69	243.0	COG2199@1|root,COG3706@2|Bacteria,1N2X1@1224|Proteobacteria,1SU4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Carbohydrate-binding family 9	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_2
DTH3_k127_7410778_5	518766.Rmar_0433	2.716e-12	76.0	COG2353@1|root,COG2353@2|Bacteria,4PBAH@976|Bacteroidetes,1FK7G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH3_k127_7410778_6	866536.Belba_2664	3.218e-11	74.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,47RR5@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
DTH3_k127_7410778_0	1303518.CCALI_00783	2.2e-96	337.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_7410778_1	497964.CfE428DRAFT_3392	6.479e-70	248.0	COG3828@1|root,COG3828@2|Bacteria,46UCF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
DTH3_k127_7410778_3	1156937.MFUM_1010028	8.996e-56	200.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,37GF0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH3_k127_7413800_4	552398.HMPREF0866_02248	5.233e-08	59.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
DTH3_k127_7413800_0	1313265.JNIE01000005_gene247	2.738e-133	437.0	COG0172@1|root,COG0172@2|Bacteria,2G3RF@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DTH3_k127_7413800_1	1304885.AUEY01000116_gene2847	1.577e-122	407.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M2X@68525|delta/epsilon subdivisions,2WJMY@28221|Deltaproteobacteria,2MIYR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_7413800_2	644282.Deba_1655	2.602e-40	168.0	COG3852@1|root,COG3852@2|Bacteria,1RCUD@1224|Proteobacteria,42R9I@68525|delta/epsilon subdivisions,2WN53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DTH3_k127_7413800_3	661478.OP10G_4206	9.095e-17	84.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
DTH3_k127_7416380_1	1122135.KB893134_gene3934	1.379e-53	196.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
DTH3_k127_7416380_0	1122135.KB893134_gene3933	2.487e-95	320.0	COG0518@1|root,COG0518@2|Bacteria,1Q2PQ@1224|Proteobacteria,2U196@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DTH3_k127_7416380_2	278957.ABEA03000195_gene491	6.812e-13	72.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia,3K8DC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7416380_3	382464.ABSI01000005_gene1185	1.324e-05	51.0	COG5010@1|root,COG5010@2|Bacteria	2|Bacteria	-	-	tadD	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,SPOR,TPR_16,TPR_19,TPR_8
DTH3_k127_7435467_2	497964.CfE428DRAFT_5737	6.008e-171	539.0	COG0673@1|root,COG0673@2|Bacteria,46UQI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_7435467_1	1396418.BATQ01000117_gene4568	2.169e-231	727.0	COG0738@1|root,COG0738@2|Bacteria,46U7F@74201|Verrucomicrobia,2IUMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DTH3_k127_7435467_0	497964.CfE428DRAFT_0141	0.0	1082.0	COG1082@1|root,COG4993@1|root,COG1082@2|Bacteria,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
DTH3_k127_7435467_3	530564.Psta_0173	7.522e-95	328.0	COG0501@1|root,COG3170@1|root,COG0501@2|Bacteria,COG3170@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH3_k127_7435467_4	497964.CfE428DRAFT_1548	2.249e-66	252.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
DTH3_k127_7440293_3	521674.Plim_0354	8.858e-62	221.0	COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
DTH3_k127_7440293_0	1123242.JH636435_gene793	2.124e-192	611.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
DTH3_k127_7440293_2	1396141.BATP01000047_gene3930	2.655e-64	225.0	COG3476@1|root,COG3476@2|Bacteria,46SXT@74201|Verrucomicrobia,2IVZD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	TspO/MBR family	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
DTH3_k127_7440293_1	1283284.AZUK01000001_gene812	7.483e-93	308.0	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,1RU3S@1236|Gammaproteobacteria,1Y501@135624|Aeromonadales	135624|Aeromonadales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
DTH3_k127_7446554_0	497964.CfE428DRAFT_1519	3.713e-158	510.0	COG2204@1|root,COG2204@2|Bacteria,46SFT@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K11384	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DTH3_k127_7446554_2	1283300.ATXB01000002_gene3058	9.308e-14	76.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
DTH3_k127_7446554_1	1304284.L21TH_1032	7.925e-16	78.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,36DSY@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
DTH3_k127_7447251_4	794903.OPIT5_07325	7.398e-25	104.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH3_k127_7447251_2	452637.Oter_0624	8.13e-49	186.0	COG3428@1|root,COG3428@2|Bacteria,46VTZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
DTH3_k127_7447251_1	452637.Oter_0623	2.064e-55	199.0	COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
DTH3_k127_7447251_6	935863.AWZR01000007_gene245	2.068e-11	67.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales	135614|Xanthomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH3_k127_7447251_3	383372.Rcas_0336	5.561e-25	122.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
DTH3_k127_7447251_7	1120949.KB903306_gene7572	1.103e-05	59.0	COG1361@1|root,COG2304@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,2I8F1@201174|Actinobacteria,4DFBB@85008|Micromonosporales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3344
DTH3_k127_7447251_5	794903.OPIT5_07325	1.499e-18	92.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DTH3_k127_7447251_0	935845.JADQ01000029_gene1230	5.11e-67	238.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
DTH3_k127_7459185_7	1288963.ADIS_2373	8.623e-31	121.0	COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,47KYW@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_7459185_8	240016.ABIZ01000001_gene1187	8.867e-24	109.0	COG2010@1|root,COG2010@2|Bacteria,46T74@74201|Verrucomicrobia,2IWN4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH3_k127_7459185_6	1123508.JH636443_gene5054	1.264e-36	154.0	COG2993@1|root,COG2993@2|Bacteria,2IZNM@203682|Planctomycetes	203682|Planctomycetes	C	COGs COG2993 Cbb3-type cytochrome oxidase cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
DTH3_k127_7459185_2	794903.OPIT5_22615	1.694e-90	316.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
DTH3_k127_7459185_9	452637.Oter_3929	0.000182	49.0	2B8Q9@1|root,321ZW@2|Bacteria,46XX6@74201|Verrucomicrobia,3K8IF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7459185_3	452637.Oter_3930	6.78e-69	250.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,3K79U@414999|Opitutae	414999|Opitutae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7459185_5	794903.OPIT5_22595	6.059e-42	163.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia,3K7Z7@414999|Opitutae	414999|Opitutae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH3_k127_7459185_4	794903.OPIT5_22590	2.684e-60	214.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
DTH3_k127_7459185_1	278957.ABEA03000189_gene958	6.083e-212	667.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
DTH3_k127_7459185_0	452637.Oter_3934	0.0	1029.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
DTH3_k127_7461399_0	251221.35213668	9.442e-101	340.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_7461399_2	661478.OP10G_3764	4.912e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_7461399_1	497964.CfE428DRAFT_2042	3.344e-80	270.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DTH3_k127_7466119_0	497964.CfE428DRAFT_2513	3.791e-189	604.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
DTH3_k127_7466119_1	497964.CfE428DRAFT_4931	1.318e-31	139.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
DTH3_k127_7466119_2	335543.Sfum_2943	3.555e-13	75.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
DTH3_k127_7472316_5	243231.GSU2460	1.599e-36	153.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
DTH3_k127_7472316_0	240016.ABIZ01000001_gene5947	1.701e-179	569.0	COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia,2ITXS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DTH3_k127_7472316_3	1122947.FR7_4282	1.637e-157	511.0	COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4H38R@909932|Negativicutes	909932|Negativicutes	G	Major Facilitator	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
DTH3_k127_7472316_1	1210884.HG799463_gene9560	1.141e-176	568.0	COG0578@1|root,COG0578@2|Bacteria,2IX2V@203682|Planctomycetes	203682|Planctomycetes	C	Glycerol-3-phosphate dehydrogenase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
DTH3_k127_7472316_4	679935.Alfi_2300	1.476e-103	344.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,2FRNM@200643|Bacteroidia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
DTH3_k127_7472316_2	497964.CfE428DRAFT_0238	1.698e-175	564.0	COG2010@1|root,COG2010@2|Bacteria,46TSG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_7481359_3	794903.OPIT5_03555	1.962e-22	104.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
DTH3_k127_7481359_0	497964.CfE428DRAFT_2938	4.256e-93	322.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DTH3_k127_7481359_2	1121472.AQWN01000001_gene239	5.843e-42	163.0	COG2859@1|root,COG2859@2|Bacteria,1V1Q4@1239|Firmicutes,24GEE@186801|Clostridia,264GJ@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
DTH3_k127_7481359_1	635013.TherJR_2166	8.875e-54	196.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,260BS@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
DTH3_k127_748250_4	481448.Minf_1864	5.638e-58	205.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,37FYY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
DTH3_k127_748250_5	32057.KB217478_gene5529	1.289e-12	73.0	COG0858@1|root,COG0858@2|Bacteria,1G6JJ@1117|Cyanobacteria,1HNRI@1161|Nostocales	1117|Cyanobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
DTH3_k127_748250_2	497964.CfE428DRAFT_1792	8.771e-69	245.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DTH3_k127_748250_1	452637.Oter_2817	1.1e-79	272.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,3K75I@414999|Opitutae	414999|Opitutae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
DTH3_k127_748250_3	1396418.BATQ01000085_gene1110	3.622e-66	239.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
DTH3_k127_748250_0	1379698.RBG1_1C00001G1779	1.054e-145	470.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH3_k127_7489880_1	1026882.MAMP_01900	8.416e-29	134.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales	72273|Thiotrichales	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	PATR
DTH3_k127_7489880_2	1142394.PSMK_04880	1.71e-13	83.0	COG2165@1|root,COG2165@2|Bacteria,2IY1V@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_7489880_3	521674.Plim_1480	8.029e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,2IYXM@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_7489880_0	1396141.BATP01000033_gene4254	3.908e-189	620.0	COG5434@1|root,COG5434@2|Bacteria,46TEZ@74201|Verrucomicrobia,2IWAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7489880_4	1463820.JOGW01000001_gene5446	0.0006578	53.0	COG1409@1|root,COG5492@1|root,COG1409@2|Bacteria,COG5492@2|Bacteria,2GKTR@201174|Actinobacteria	201174|Actinobacteria	N	polysaccharide lyase family 8	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Lyase_8,Lyase_8_C,Lyase_8_N
DTH3_k127_7490628_0	489825.LYNGBM3L_02020	8.642e-154	494.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria,1H8F2@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
DTH3_k127_7490628_1	246197.MXAN_4314	7.142e-14	76.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2Z1G5@29|Myxococcales	28221|Deltaproteobacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
DTH3_k127_7502380_0	392500.Swoo_0456	8.046e-38	153.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,1RQJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH3_k127_7502380_1	382464.ABSI01000013_gene1773	1.1e-10	75.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7502380_2	497964.CfE428DRAFT_3795	1.014e-09	72.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7505762_3	1236497.BAJQ01000001_gene569	0.0008703	43.0	COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,2FNFV@200643|Bacteroidia	976|Bacteroidetes	G	F5 8 type C domain protein	fucA	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH3_k127_7505762_0	278957.ABEA03000202_gene4286	3.418e-130	439.0	2A266@1|root,30QGS@2|Bacteria,46Y1D@74201|Verrucomicrobia,3K8SA@414999|Opitutae	414999|Opitutae	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
DTH3_k127_7505762_1	180332.JTGN01000021_gene1375	2.381e-11	70.0	COG5012@1|root,COG5012@2|Bacteria,1V82H@1239|Firmicutes,24JSA@186801|Clostridia	186801|Clostridia	S	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7509842_1	497964.CfE428DRAFT_4324	9.766e-29	117.0	2BXG3@1|root,2Z82R@2|Bacteria,46TKW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
DTH3_k127_7509842_0	234267.Acid_7084	8.658e-207	646.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
DTH3_k127_7509842_2	338963.Pcar_0542	7.625e-07	51.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2WIJ0@28221|Deltaproteobacteria,43U3N@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DTH3_k127_7525464_2	1121957.ATVL01000007_gene1544	1.681e-69	247.0	COG4692@1|root,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes,47YCC@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2,Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
DTH3_k127_7525464_1	240016.ABIZ01000001_gene4842	7.599e-112	373.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_7525464_0	497964.CfE428DRAFT_1943	3.206e-130	423.0	COG2133@1|root,COG2133@2|Bacteria,46THQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_7526186_1	497964.CfE428DRAFT_2511	1.644e-36	141.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
DTH3_k127_7526186_2	398767.Glov_1965	1.485e-23	111.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,42ZGY@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH3_k127_7526186_3	401526.TcarDRAFT_1486	4.406e-23	111.0	COG1127@1|root,COG1127@2|Bacteria,1UGV0@1239|Firmicutes,4H251@909932|Negativicutes	909932|Negativicutes	Q	ABC transporter, ATP-binding protein	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DTH3_k127_7526186_4	243231.GSU1899	1.259e-05	57.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43UDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DTH3_k127_7526186_5	1121468.AUBR01000018_gene2682	0.0001166	53.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DTH3_k127_7526186_0	555088.DealDRAFT_0634	7.26e-58	221.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,42JHW@68298|Syntrophomonadaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DTH3_k127_7528296_2	1123242.JH636435_gene944	1.057e-49	187.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_7528296_6	452637.Oter_1389	5.972e-05	45.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH3_k127_7528296_4	452637.Oter_1389	3.509e-16	81.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DTH3_k127_7528296_3	237368.SCABRO_03851	1.138e-16	90.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_7528296_0	1123242.JH636435_gene944	1.22e-107	367.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_7528296_1	497964.CfE428DRAFT_0215	1.901e-58	213.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
DTH3_k127_7528296_5	1303518.CCALI_02394	1.695e-15	87.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_7532728_2	502025.Hoch_3916	1.011e-06	57.0	COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7532728_1	1396141.BATP01000061_gene4541	2.519e-128	425.0	28N64@1|root,2ZBFG@2|Bacteria,46Z9S@74201|Verrucomicrobia,2IWQS@203494|Verrucomicrobiae	2|Bacteria	S	Peptidase of plants and bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BSP
DTH3_k127_7532728_0	481448.Minf_1559	0.0	1146.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,37G1Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
DTH3_k127_7545107_1	366602.Caul_1283	1.901e-26	113.0	COG2730@1|root,COG2730@2|Bacteria,1N2XP@1224|Proteobacteria,2TSHY@28211|Alphaproteobacteria,2KIB4@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
DTH3_k127_7545107_0	886293.Sinac_4026	2.145e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DTH3_k127_7547086_0	583355.Caka_0779	4.724e-79	278.0	COG2304@1|root,COG2304@2|Bacteria,46SKE@74201|Verrucomicrobia,3K7H6@414999|Opitutae	414999|Opitutae	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
DTH3_k127_7547086_1	1167006.UWK_00742	5.713e-71	253.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
DTH3_k127_7547086_2	1506583.JQJY01000007_gene4146	4.345e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,2NU2K@237|Flavobacterium	976|Bacteroidetes	S	BatD protein	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
DTH3_k127_7558673_0	289376.THEYE_A0114	8.44e-116	378.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DTH3_k127_7558673_3	313628.LNTAR_07769	7.923e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_7558673_1	497964.CfE428DRAFT_5370	7.931e-101	333.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
DTH3_k127_7605915_1	1121333.JMLH01000086_gene1317	1.502e-05	59.0	COG1196@1|root,COG1524@1|root,COG1196@2|Bacteria,COG1524@2|Bacteria,1UKCI@1239|Firmicutes,3VUT8@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,Laminin_G_3
DTH3_k127_7605915_0	1121920.AUAU01000009_gene1881	5.134e-26	126.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH3_k127_7605915_2	1122927.KB895414_gene5036	4.517e-05	57.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli,26QRR@186822|Paenibacillaceae	91061|Bacilli	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM
DTH3_k127_7612567_1	1469557.JSWF01000021_gene726	5.297e-24	120.0	COG0739@1|root,COG3266@1|root,COG4886@1|root,COG0739@2|Bacteria,COG3266@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
DTH3_k127_7612567_0	243090.RB4375	1.111e-25	125.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF642
DTH3_k127_7612567_2	304371.MCP_2796	5.622e-16	93.0	arCOG06738@1|root,arCOG06738@2157|Archaea	2157|Archaea	O	extracellular matrix structural constituent	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Beta_helix,Calx-beta,CarboxypepD_reg,NosD,Peptidase_S8
DTH3_k127_7620035_3	755178.Cyan10605_0953	6.969e-11	73.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria	1117|Cyanobacteria	M	bicarbonate transporter, IctB family	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
DTH3_k127_7620035_1	459349.CLOAM0160	1.758e-41	166.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
DTH3_k127_7620035_0	497964.CfE428DRAFT_3485	3.019e-175	557.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_7620035_2	28444.JODQ01000006_gene629	4.713e-35	142.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4EJ7V@85012|Streptosporangiales	201174|Actinobacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
DTH3_k127_7620035_4	1123242.JH636434_gene3574	1.856e-06	54.0	COG2133@1|root,COG2133@2|Bacteria,2IXUJ@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH3_k127_7630591_0	864702.OsccyDRAFT_2745	2.671e-161	563.0	COG2931@1|root,COG2931@2|Bacteria,1GHDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH3_k127_7636979_2	497964.CfE428DRAFT_5469	8.13e-42	161.0	COG2067@1|root,COG2067@2|Bacteria,46SR3@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
DTH3_k127_7636979_0	452637.Oter_1792	1.231e-174	562.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_7636979_1	204669.Acid345_2517	6.552e-72	251.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
DTH3_k127_7636979_3	1122917.KB899659_gene5085	3.584e-32	130.0	2E9V0@1|root,3340V@2|Bacteria,1VBMU@1239|Firmicutes,4IRRQ@91061|Bacilli,26ZN3@186822|Paenibacillaceae	91061|Bacilli	I	carotenoid biosynthetic process	-	-	-	ko:K10212	ko00906,map00906	-	R07656	RC00041	ko00000,ko00001,ko01000	-	-	-	-
DTH3_k127_7639204_8	1123229.AUBC01000012_gene2680	4.873e-23	106.0	COG1172@1|root,COG1172@2|Bacteria,1MV4F@1224|Proteobacteria,2TT2T@28211|Alphaproteobacteria,3JWPU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
DTH3_k127_7639204_1	1089551.KE386572_gene1627	1.767e-165	545.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,4BR8I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH3_k127_7639204_7	35754.JNYJ01000079_gene4336	2.986e-45	181.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4DDXV@85008|Micromonosporales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
DTH3_k127_7639204_5	1089551.KE386572_gene1625	3.168e-84	294.0	COG1879@1|root,COG1879@2|Bacteria,1QJ9B@1224|Proteobacteria,2U8ZS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
DTH3_k127_7639204_6	761193.Runsl_3634	3.994e-75	261.0	COG1082@1|root,COG1082@2|Bacteria,4NPBS@976|Bacteroidetes,47Q6G@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_7639204_3	1122917.KB899667_gene3587	8.99e-97	328.0	COG2085@1|root,COG2085@2|Bacteria,1TWYH@1239|Firmicutes	1239|Firmicutes	S	Phosphogluconate dehydrogenase (decarboxylating) C-term	-	-	-	-	-	-	-	-	-	-	-	-	IlvN,PGDH_C
DTH3_k127_7639204_4	344747.PM8797T_05400	3.793e-87	304.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_7639204_0	1123508.JH636448_gene7659	1.113e-231	725.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
DTH3_k127_7639204_2	525904.Tter_1997	4.311e-125	409.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_7639204_9	661478.OP10G_4770	1.03e-14	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_7639204_10	1385935.N836_03200	1.271e-11	76.0	COG2207@1|root,COG2207@2|Bacteria,1GBJH@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Response_reg
DTH3_k127_7639204_11	886293.Sinac_6937	1.772e-06	52.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_7640958_0	1173028.ANKO01000141_gene601	1.174e-51	212.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G13T@1117|Cyanobacteria,1H77Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
DTH3_k127_7649144_0	1453501.JELR01000001_gene2132	8.711e-146	480.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,1RR8K@1236|Gammaproteobacteria,466XF@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
DTH3_k127_7652326_2	497964.CfE428DRAFT_0276	3.098e-37	145.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
DTH3_k127_7652326_5	1396141.BATP01000035_gene4053	3.12e-17	95.0	29ZA9@1|root,30M8M@2|Bacteria,46XI8@74201|Verrucomicrobia,2IVZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7652326_4	926554.KI912668_gene5115	4.792e-22	108.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DTH3_k127_7652326_1	521011.Mpal_2181	1.055e-38	154.0	COG0500@1|root,arCOG01789@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DTH3_k127_7652326_8	1246445.ANAY01000001_gene403	3.581e-05	56.0	COG0438@1|root,COG0438@2|Bacteria,2GNUU@201174|Actinobacteria,4EI9I@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH3_k127_7652326_9	491915.Aflv_2575	0.0001404	53.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HCKY@91061|Bacilli,21WRB@150247|Anoxybacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_16,TPR_8
DTH3_k127_7652326_3	690850.Desaf_2652	9.274e-27	124.0	COG0438@1|root,COG0438@2|Bacteria,1R9QG@1224|Proteobacteria,42PQQ@68525|delta/epsilon subdivisions,2WTQJ@28221|Deltaproteobacteria,2M9KJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
DTH3_k127_7652326_0	595537.Varpa_3992	2.841e-61	219.0	COG4122@1|root,COG4122@2|Bacteria,1NR4H@1224|Proteobacteria	1224|Proteobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7652326_6	326424.FRAAL2042	8.958e-17	90.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
DTH3_k127_7652326_7	1232410.KI421412_gene245	3.412e-13	81.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,43VVF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
DTH3_k127_7702912_0	404589.Anae109_0983	4.626e-154	493.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42NZ7@68525|delta/epsilon subdivisions,2WKSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH3_k127_7702912_1	398512.JQKC01000004_gene5249	2.686e-93	327.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DTH3_k127_7710364_0	497964.CfE428DRAFT_5595	2.401e-145	466.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DTH3_k127_7710364_2	794903.OPIT5_02450	1.155e-65	226.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,3K7YQ@414999|Opitutae	414999|Opitutae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DTH3_k127_7710364_3	452637.Oter_0229	4.895e-56	199.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,3K7QA@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DTH3_k127_7710364_1	497964.CfE428DRAFT_0484	2.015e-87	291.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DTH3_k127_7720726_2	497964.CfE428DRAFT_2615	1.448e-25	111.0	COG0451@1|root,COG0451@2|Bacteria,46SWG@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,SKI
DTH3_k127_7720726_0	382464.ABSI01000011_gene3025	2.674e-131	428.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH3_k127_7720726_1	1232410.KI421415_gene3077	9.357e-73	254.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
DTH3_k127_7720726_4	1484460.JSWG01000009_gene451	1.379e-12	77.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4NINJ@976|Bacteroidetes,1HZEY@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	LTD
DTH3_k127_7720726_3	278957.ABEA03000149_gene4042	5.435e-19	88.0	2BGYY@1|root,32AZ2@2|Bacteria,46ZHP@74201|Verrucomicrobia,3K9QU@414999|Opitutae	414999|Opitutae	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH3_k127_77208_4	1403819.BATR01000024_gene820	2.412e-47	173.0	COG2201@1|root,COG2201@2|Bacteria,46TVZ@74201|Verrucomicrobia,2IUSQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NT	CheB methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,Response_reg
DTH3_k127_77208_0	1403819.BATR01000024_gene821	1.901e-247	790.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,46UEP@74201|Verrucomicrobia,2IUVS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
DTH3_k127_77208_3	748247.AZKH_p0390	5.378e-58	210.0	COG0835@1|root,COG0835@2|Bacteria,1RIUD@1224|Proteobacteria,2VSFU@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis signal transduction protein	wspD	-	-	ko:K13489	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
DTH3_k127_77208_2	240016.ABIZ01000001_gene190	3.342e-99	338.0	COG1352@1|root,COG1352@2|Bacteria,46U91@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Methyltransferase, chemotaxis proteins	-	-	-	-	-	-	-	-	-	-	-	-	CheR,TPR_2
DTH3_k127_77208_5	220664.PFL_1130	8.674e-37	144.0	COG0835@1|root,COG0835@2|Bacteria,1N0R3@1224|Proteobacteria,1SG9X@1236|Gammaproteobacteria,1YQ6J@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	NT	Two component signalling adaptor domain	wspB	-	-	ko:K13488	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
DTH3_k127_77208_1	1122132.AQYH01000005_gene433	2.668e-124	410.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,4B9N4@82115|Rhizobiaceae	28211|Alphaproteobacteria	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
DTH3_k127_7723825_0	1173027.Mic7113_1425	0.0	1262.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H9JF@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
DTH3_k127_7723825_2	1156844.KB891831_gene4705	1.818e-119	400.0	COG0366@1|root,COG0366@2|Bacteria,2GN52@201174|Actinobacteria	201174|Actinobacteria	G	Alpha amylase catalytic	amyA	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
DTH3_k127_7723825_5	497964.CfE428DRAFT_4835	1.991e-43	161.0	COG4747@1|root,COG4747@2|Bacteria,46WIS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
DTH3_k127_7723825_4	1051632.TPY_0383	7.052e-56	207.0	COG2912@1|root,COG2912@2|Bacteria,1VXJ8@1239|Firmicutes,25294@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
DTH3_k127_7723825_3	1396418.BATQ01000136_gene3705	3.452e-91	314.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
DTH3_k127_7723825_1	1396141.BATP01000003_gene5199	8.261e-171	546.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
DTH3_k127_7723825_6	497964.CfE428DRAFT_2283	4.239e-28	117.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DTH3_k127_7723825_8	1210884.HG799464_gene10603	3.635e-13	83.0	2A5PP@1|root,30UEI@2|Bacteria,2J4IH@203682|Planctomycetes	1210884.HG799464_gene10603|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7723825_7	382464.ABSI01000014_gene1430	4.445e-17	83.0	COG2716@1|root,COG2716@2|Bacteria,46VWB@74201|Verrucomicrobia,2IVUS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_6
DTH3_k127_7746449_12	1238450.VIBNISOn1_1470029	1.045e-28	128.0	COG3332@1|root,COG3332@2|Bacteria,1RE1W@1224|Proteobacteria,1S59Q@1236|Gammaproteobacteria,1XU3T@135623|Vibrionales	135623|Vibrionales	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
DTH3_k127_7746449_2	1210884.HG799463_gene9621	6.845e-113	384.0	COG0189@1|root,COG0586@1|root,COG3332@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,COG3332@2|Bacteria	2|Bacteria	S	Transport and Golgi organisation 2	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	RimK,SNARE_assoc,TANGO2
DTH3_k127_7746449_10	1123070.KB899257_gene2311	5.734e-33	134.0	COG2318@1|root,COG2318@2|Bacteria,46WF2@74201|Verrucomicrobia,2IWE9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7746449_8	929703.KE386491_gene4207	1.745e-35	139.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
DTH3_k127_7746449_9	1502851.FG93_03399	1.271e-34	139.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
DTH3_k127_7746449_3	864702.OsccyDRAFT_4593	1.054e-95	321.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria,1H9H5@1150|Oscillatoriales	1117|Cyanobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DTH3_k127_7746449_13	1123278.KB893444_gene1666	5.527e-25	115.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
DTH3_k127_7746449_11	382464.ABSI01000012_gene2101	4.688e-32	143.0	COG0526@1|root,COG4935@1|root,COG0526@2|Bacteria,COG4935@2|Bacteria,46UYI@74201|Verrucomicrobia,2IWE7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH3_k127_7746449_6	382464.ABSI01000010_gene3251	1.716e-41	164.0	COG0526@1|root,COG3210@1|root,COG0526@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Omp28
DTH3_k127_7746449_5	452637.Oter_0302	8.817e-68	238.0	COG5429@1|root,COG5429@2|Bacteria,46W7J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
DTH3_k127_7746449_14	1185653.A1A1_08864	3.554e-18	98.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26EYU@186818|Planococcaceae	91061|Bacilli	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH3_k127_7746449_16	344747.PM8797T_01589	4.057e-06	58.0	COG3266@1|root,COG3266@2|Bacteria,2IZW5@203682|Planctomycetes	203682|Planctomycetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7746449_1	861299.J421_1876	5.753e-184	594.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
DTH3_k127_7746449_7	497964.CfE428DRAFT_5990	1.067e-38	153.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_7746449_15	1267534.KB906760_gene1563	9.717e-15	77.0	29A7N@1|root,2ZX8K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7746449_4	1396418.BATQ01000011_gene4474	1.535e-77	264.0	COG3576@1|root,COG3576@2|Bacteria,46SQM@74201|Verrucomicrobia,2IVR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
DTH3_k127_7746449_0	1116472.MGMO_17c00060	1.236e-215	691.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XEIK@135618|Methylococcales	135618|Methylococcales	KT	PFAM RNA polymerase sigma factor 54, interaction	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
DTH3_k127_7753999_4	555778.Hneap_2214	7.948e-94	323.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria,1WZMA@135613|Chromatiales	135613|Chromatiales	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
DTH3_k127_7753999_9	794903.OPIT5_14550	8.647e-28	121.0	COG2165@1|root,COG2165@2|Bacteria,46Y3B@74201|Verrucomicrobia,3K8VC@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH3_k127_7753999_11	313606.M23134_01193	5.16e-13	82.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
DTH3_k127_7753999_10	649831.L083_3819	5.947e-19	102.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7753999_1	489825.LYNGBM3L_21200	5.408e-138	462.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH3_k127_7753999_2	335543.Sfum_3555	7.66e-138	463.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2MSIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DTH3_k127_7753999_6	1173026.Glo7428_0927	3.521e-39	154.0	COG0110@1|root,COG0110@2|Bacteria,1G9TY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
DTH3_k127_7753999_7	497964.CfE428DRAFT_2920	1.958e-38	152.0	COG0110@1|root,COG0110@2|Bacteria,46T6H@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH3_k127_7753999_0	335543.Sfum_3551	1.399e-177	563.0	COG0438@1|root,COG0438@2|Bacteria,1RAGT@1224|Proteobacteria,42Y8X@68525|delta/epsilon subdivisions,2WU97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7753999_8	1449976.KALB_4422	2.152e-34	147.0	COG0500@1|root,COG0500@2|Bacteria,2INXQ@201174|Actinobacteria,4EDFK@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DTH3_k127_7753999_3	489825.LYNGBM3L_21170	5.811e-136	443.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
DTH3_k127_7753999_5	251229.Chro_0879	1.244e-70	252.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,3VKAC@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH3_k127_7753999_12	419665.Maeo_0425	1.104e-06	50.0	COG2120@1|root,arCOG03460@2157|Archaea,2Y69J@28890|Euryarchaeota,23RSD@183939|Methanococci	183939|Methanococci	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DTH3_k127_7759974_0	497964.CfE428DRAFT_4539	2.573e-295	922.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
DTH3_k127_7759974_5	649831.L083_1093	1.18e-43	171.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4D8I2@85008|Micromonosporales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
DTH3_k127_7759974_2	886293.Sinac_2390	6.877e-231	727.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_7759974_6	696747.NIES39_O06680	1.191e-10	73.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
DTH3_k127_7759974_4	886293.Sinac_5427	6.984e-96	321.0	COG3485@1|root,COG3485@2|Bacteria,2IYK6@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
DTH3_k127_7759974_3	521674.Plim_3842	5.193e-102	340.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
DTH3_k127_7759974_1	497964.CfE428DRAFT_5375	3.487e-247	786.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,46U46@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH3_k127_7760618_0	886293.Sinac_5601	3.481e-157	514.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_7760618_1	886293.Sinac_2797	6.567e-119	404.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2,ThuA
DTH3_k127_7760775_4	1121920.AUAU01000004_gene839	1.114e-61	217.0	COG0590@1|root,COG0590@2|Bacteria,3Y4ZN@57723|Acidobacteria	57723|Acidobacteria	FJ	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
DTH3_k127_7760775_2	1128427.KB904821_gene1968	1.05e-82	289.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DTH3_k127_7760775_6	292564.Cyagr_1911	9.627e-24	114.0	COG2337@1|root,COG2337@2|Bacteria,1G7JA@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM PemK-like protein	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DTH3_k127_7760775_0	497964.CfE428DRAFT_5010	4.637e-175	560.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7760775_1	530564.Psta_1962	1.359e-94	327.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7760775_9	1120950.KB892753_gene6100	2.551e-13	83.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_39
DTH3_k127_7760775_3	479434.Sthe_1775	3.279e-71	249.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_7760775_7	1206730.BAGA01000116_gene4720	1.585e-23	118.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4FTZW@85025|Nocardiaceae	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_7760775_5	868131.MSWAN_1282	3.707e-31	132.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH3_k127_7760775_8	497964.CfE428DRAFT_3740	1.234e-13	73.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_7782904_0	530564.Psta_1928	1.192e-165	538.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_7782923_9	497964.CfE428DRAFT_4704	0.0001752	49.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM outer membrane chaperone Skp (OmpH)	hlpA	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
DTH3_k127_7782923_7	1166018.FAES_3046	7.61e-15	90.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DTH3_k127_7782923_2	247490.KSU1_C0714	7.318e-129	454.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
DTH3_k127_7782923_1	1156937.MFUM_230019	4.609e-159	531.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,37GCF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
DTH3_k127_7782923_0	1131269.AQVV01000050_gene421	9.477e-182	581.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DTH3_k127_7782923_5	1042375.AFPL01000055_gene2315	2.289e-61	222.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,467K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
DTH3_k127_7782923_8	1396141.BATP01000023_gene664	1.02e-10	73.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
DTH3_k127_7782923_4	909663.KI867150_gene1086	2.353e-64	231.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_7782923_3	404589.Anae109_0137	1.854e-74	269.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
DTH3_k127_7782923_6	313628.LNTAR_06814	4.399e-15	76.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
DTH3_k127_7786771_1	1123277.KB893176_gene3715	7.294e-56	199.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,SLH
DTH3_k127_7786771_0	521674.Plim_1676	1.632e-101	341.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH3_k127_7801375_0	518766.Rmar_0899	1.248e-174	561.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH3_k127_7804504_0	1123508.JH636444_gene5476	7.716e-175	567.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
DTH3_k127_7804504_1	243090.RB5616	1.514e-164	526.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
DTH3_k127_7820564_0	234267.Acid_2605	5.011e-89	301.0	COG2133@1|root,COG2133@2|Bacteria,3Y3FI@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_7820564_1	497964.CfE428DRAFT_0418	3.756e-72	255.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DTH3_k127_7824813_2	452637.Oter_0987	9.566e-36	139.0	COG2730@1|root,COG2730@2|Bacteria,46US1@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DTH3_k127_7824813_3	635013.TherJR_0274	1.646e-17	89.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,261WW@186807|Peptococcaceae	186801|Clostridia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
DTH3_k127_7824813_0	1210884.HG799466_gene12649	4.446e-104	344.0	COG1131@1|root,COG1131@2|Bacteria,2IY1H@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_7824813_1	1123508.JH636441_gene3735	2.164e-88	314.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
DTH3_k127_7831161_1	570268.ANBB01000059_gene4179	5.439e-64	224.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4EG4M@85012|Streptosporangiales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
DTH3_k127_7831161_2	1121472.AQWN01000007_gene1087	4.443e-24	107.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,262CP@186807|Peptococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
DTH3_k127_7831161_0	1396418.BATQ01000129_gene4821	5.864e-132	442.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,2ITGI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DTH3_k127_7831161_3	861299.J421_5618	1.858e-06	51.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	3.2.1.15	ko:K01184	ko00040,ko01100,map00040,map01100	M00081	R01982,R02360	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta_helix,Glyco_hydro_28,Pectate_lyase_3
DTH3_k127_7836104_1	497964.CfE428DRAFT_2131	1.439e-36	147.0	29NX7@1|root,309VB@2|Bacteria,46WPG@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7836104_0	595460.RRSWK_03709	7.285e-91	328.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DTH3_k127_7836104_2	1341155.FSS13T_06860	7.826e-14	74.0	COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia,2NTJ9@237|Flavobacterium	976|Bacteroidetes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH3_k127_7836916_1	530564.Psta_1454	3.706e-100	328.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH3_k127_7836916_0	497964.CfE428DRAFT_6615	1.198e-222	701.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
DTH3_k127_7836916_3	452637.Oter_0903	1.166e-22	102.0	COG1917@1|root,COG1917@2|Bacteria,46WMQ@74201|Verrucomicrobia,3K8IQ@414999|Opitutae	414999|Opitutae	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DTH3_k127_7836916_2	497964.CfE428DRAFT_0298	1.878e-23	106.0	COG2258@1|root,COG2258@2|Bacteria,46VBP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7838154_5	696281.Desru_0139	1.258e-16	84.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,2609K@186807|Peptococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DTH3_k127_7838154_1	595537.Varpa_5109	4.216e-90	299.0	COG0847@1|root,COG0847@2|Bacteria,1RDF2@1224|Proteobacteria,2W1A3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7838154_3	452637.Oter_2376	1.102e-58	208.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH3_k127_7838154_4	246197.MXAN_1687	1.278e-31	137.0	2A102@1|root,30P5F@2|Bacteria,1NQ9E@1224|Proteobacteria	1224|Proteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
DTH3_k127_7838154_2	1156937.MFUM_170024	1.714e-87	295.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,37G7G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DTH3_k127_7838154_0	511062.GU3_08515	4.755e-156	503.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1Y3ZI@135624|Aeromonadales	135624|Aeromonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DTH3_k127_7870448_1	1303518.CCALI_02579	8.909e-22	106.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_7870448_0	1117315.AHCA01000001_gene2142	5.459e-25	119.0	COG3537@1|root,COG5492@1|root,COG3537@2|Bacteria,COG5492@2|Bacteria,1R4VD@1224|Proteobacteria,1RZJ5@1236|Gammaproteobacteria,2Q5IB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
DTH3_k127_7882697_2	517417.Cpar_0661	1.054e-24	104.0	COG1225@1|root,COG1225@2|Bacteria,1FDZX@1090|Chlorobi	1090|Chlorobi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH3_k127_7882697_1	497964.CfE428DRAFT_0793	7.899e-74	251.0	COG0450@1|root,COG0450@2|Bacteria,46STI@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DTH3_k127_7882697_0	1123276.KB893270_gene4720	1.935e-199	632.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,47KJR@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_7882697_3	1267534.KB906758_gene2376	1.341e-21	97.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_7885906_1	497964.CfE428DRAFT_5031	4.847e-130	426.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DTH3_k127_7885906_0	1396418.BATQ01000147_gene3609	2.273e-218	699.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_7889453_2	1485544.JQKP01000002_gene1415	2.952e-70	246.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_7889453_3	65093.PCC7418_1588	4.193e-55	201.0	2EWKK@1|root,33PYP@2|Bacteria,1GC1A@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7889453_0	1173263.Syn7502_02619	6.382e-126	413.0	COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1H2TB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DTH3_k127_7889453_1	1198232.CYCME_1216	1.094e-75	259.0	COG1715@1|root,COG1715@2|Bacteria,1R2JZ@1224|Proteobacteria,1T5RK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7889453_4	696747.NIES39_C00350	2.104e-06	50.0	COG0863@1|root,COG0863@2|Bacteria,1G1WV@1117|Cyanobacteria,1HA05@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DTH3_k127_7893639_5	234267.Acid_2129	3.334e-69	241.0	COG0693@1|root,COG0693@2|Bacteria,3Y3JB@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
DTH3_k127_7893639_3	641524.ADICYQ_0788	4.548e-76	267.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_7893639_4	378806.STAUR_4743	2.66e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,43A1N@68525|delta/epsilon subdivisions,2X25S@28221|Deltaproteobacteria,2YYJ4@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase dehydratase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DTH3_k127_7893639_6	177437.HRM2_24220	4.509e-55	200.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_7893639_0	1121440.AUMA01000005_gene2707	3.151e-135	440.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2WNAF@28221|Deltaproteobacteria,2M9I9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
DTH3_k127_7893639_1	886293.Sinac_2616	3.195e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH3_k127_7893639_8	324602.Caur_3413	2.115e-14	87.0	COG0497@1|root,COG1196@1|root,COG0497@2|Bacteria,COG1196@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7893639_7	349521.HCH_00950	2.466e-23	109.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DTH3_k127_7893639_2	1396141.BATP01000032_gene4314	1.337e-91	313.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH3_k127_790141_1	497964.CfE428DRAFT_2511	1.1e-67	235.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
DTH3_k127_790141_0	1380394.JADL01000003_gene4962	1.684e-213	690.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
DTH3_k127_790141_3	1123399.AQVE01000001_gene684	3.635e-48	184.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
DTH3_k127_790141_2	449447.MAE_29050	1.566e-48	199.0	COG1621@1|root,COG2931@1|root,COG1621@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
DTH3_k127_790141_4	56110.Oscil6304_2123	1.911e-26	127.0	COG2931@1|root,COG2931@2|Bacteria,1G4IS@1117|Cyanobacteria,1HAFZ@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
DTH3_k127_7906552_0	1210884.HG799470_gene14529	1.605e-314	987.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH3_k127_7906552_1	794903.OPIT5_24290	7.562e-06	48.0	COG2165@1|root,COG2165@2|Bacteria,46YNG@74201|Verrucomicrobia,3K9VP@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH3_k127_7924272_4	382464.ABSI01000013_gene1549	2.71e-28	132.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH3_k127_7924272_3	247490.KSU1_D0514	1.622e-43	179.0	COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14
DTH3_k127_7924272_2	234267.Acid_6247	2.686e-73	263.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_7924272_1	497964.CfE428DRAFT_6473	4.385e-131	432.0	COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DTH3_k127_7924272_0	497964.CfE428DRAFT_6472	5.509e-174	550.0	COG0022@1|root,COG0022@2|Bacteria,46UID@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DTH3_k127_7924272_5	1123070.KB899260_gene2054	1.699e-10	62.0	COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia,2ITVD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH3_k127_7945961_0	428125.CLOLEP_03042	5.056e-81	287.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
DTH3_k127_7945961_2	1219084.AP014508_gene1338	3.044e-14	89.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DTH3_k127_7945961_1	497964.CfE428DRAFT_5353	2.514e-20	109.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
DTH3_k127_7945961_3	1158146.KB907123_gene599	0.0009561	48.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
DTH3_k127_7950932_0	243090.RB10165	4.068e-137	462.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
DTH3_k127_7950932_1	935567.JAES01000002_gene763	4.634e-30	121.0	COG3970@1|root,COG3970@2|Bacteria,1MVA2@1224|Proteobacteria,1S18A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
DTH3_k127_7955514_4	1232437.KL662027_gene2817	4.231e-07	62.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQGJ@28221|Deltaproteobacteria,2MKF4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH3_k127_7955514_2	1396418.BATQ01000117_gene4594	3.05e-213	672.0	2DBKQ@1|root,2Z9U7@2|Bacteria,46XD4@74201|Verrucomicrobia,2IVHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7955514_3	641524.ADICYQ_2511	5.242e-150	488.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
DTH3_k127_7955514_1	1123242.JH636434_gene5259	4.486e-226	708.0	COG3119@1|root,COG3119@2|Bacteria,2IX9P@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_7955514_0	1123242.JH636434_gene5260	1.596e-270	857.0	COG4654@1|root,COG4654@2|Bacteria,2J54P@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_7958987_0	497964.CfE428DRAFT_2659	1.223e-161	522.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DTH3_k127_7958987_1	497964.CfE428DRAFT_2658	8.483e-149	479.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH3_k127_7958987_3	497964.CfE428DRAFT_2657	8.526e-73	267.0	COG5414@1|root,COG5414@2|Bacteria,46VD3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	histone acetyltransferase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7958987_2	497964.CfE428DRAFT_2656	3.523e-127	426.0	2EQIM@1|root,2ZBQ8@2|Bacteria,46TFZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
DTH3_k127_7958987_5	497964.CfE428DRAFT_2655	4.275e-26	110.0	2ES4R@1|root,33JPJ@2|Bacteria,46T9B@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7958987_6	398767.Glov_3581	3.149e-14	82.0	2B0DH@1|root,31SQS@2|Bacteria,1P6ED@1224|Proteobacteria,4328H@68525|delta/epsilon subdivisions,2WXMR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_7958987_4	439235.Dalk_0968	3.912e-31	129.0	2ECUE@1|root,336RY@2|Bacteria,1P3V9@1224|Proteobacteria,431ZA@68525|delta/epsilon subdivisions,2WX45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_796460_0	41431.PCC8801_4418	2.415e-72	254.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,3KFP8@43988|Cyanothece	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
DTH3_k127_796460_1	765869.BDW_02925	0.000488	48.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2MT92@213481|Bdellovibrionales,2WRNT@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
DTH3_k127_7984911_1	497964.CfE428DRAFT_3359	9.736e-195	621.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
DTH3_k127_7984911_0	497964.CfE428DRAFT_0727	2.027e-236	741.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia	74201|Verrucomicrobia	C	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DTH3_k127_8010768_0	344747.PM8797T_03935	7.63e-214	679.0	COG0457@1|root,COG0457@2|Bacteria,2IXP3@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_16
DTH3_k127_8010768_1	243090.RB11088	1.586e-205	660.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DTH3_k127_8023203_0	204669.Acid345_4052	2.414e-317	994.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
DTH3_k127_8023985_8	68194.JNXR01000005_gene4614	2.091e-09	60.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
DTH3_k127_8023985_3	497964.CfE428DRAFT_2254	2.825e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_8023985_1	661478.OP10G_0808	3.175e-114	378.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
DTH3_k127_8023985_4	886293.Sinac_5728	6.485e-72	248.0	COG2264@1|root,COG2264@2|Bacteria,2J3H0@203682|Planctomycetes	203682|Planctomycetes	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DTH3_k127_8023985_2	497964.CfE428DRAFT_2167	4.985e-106	361.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
DTH3_k127_8023985_0	497964.CfE428DRAFT_2151	3.074e-128	418.0	COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DTH3_k127_8023985_6	903814.ELI_3999	2.168e-41	156.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,25W96@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DTH3_k127_8023985_5	382464.ABSI01000012_gene2250	1.238e-50	183.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DTH3_k127_8023985_7	497964.CfE428DRAFT_4167	3.514e-15	76.0	COG1208@1|root,COG1208@2|Bacteria,46SP1@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DTH3_k127_8024496_2	596151.DesfrDRAFT_1412	4.135e-24	113.0	COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,2MBT8@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH3_k127_8024496_0	497964.CfE428DRAFT_2959	1.585e-46	178.0	2ED0A@1|root,336X9@2|Bacteria,46TCE@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8024496_1	554065.XP_005846247.1	6.902e-36	143.0	COG1011@1|root,KOG3085@2759|Eukaryota,382V1@33090|Viridiplantae	33090|Viridiplantae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8024496_3	760568.Desku_0027	1.914e-19	89.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,2612W@186807|Peptococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
DTH3_k127_8040053_5	485918.Cpin_3318	4.195e-32	129.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,1IY2W@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8040053_3	1142394.PSMK_13110	3.979e-73	257.0	COG1082@1|root,COG1082@2|Bacteria,2IXZ6@203682|Planctomycetes	203682|Planctomycetes	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_8040053_2	1142394.PSMK_12790	4.967e-83	287.0	COG0673@1|root,COG0673@2|Bacteria,2IY6G@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_8040053_0	1210884.HG799471_gene14593	5.195e-141	466.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXJQ@203682|Planctomycetes	203682|Planctomycetes	C	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Cytochrom_C
DTH3_k127_8040053_6	1353531.AZNX01000014_gene3221	7.225e-23	113.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
DTH3_k127_8040053_4	1536773.R70331_08785	1.194e-43	176.0	COG1520@1|root,COG1520@2|Bacteria,1UIHU@1239|Firmicutes,4ISIB@91061|Bacilli,2773B@186822|Paenibacillaceae	91061|Bacilli	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8040053_1	1123508.JH636450_gene7203	5.395e-135	444.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Laminin_G_3
DTH3_k127_807758_5	1403819.BATR01000033_gene1102	3.353e-15	79.0	COG1526@1|root,COG1526@2|Bacteria,46SPA@74201|Verrucomicrobia,2IUBY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FdhD/NarQ family	-	-	-	-	-	-	-	-	-	-	-	-	FdhD-NarQ
DTH3_k127_807758_3	497964.CfE428DRAFT_5396	8.751e-36	143.0	2DQE3@1|root,3368V@2|Bacteria,46WIA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_807758_1	497964.CfE428DRAFT_2419	5.51e-126	409.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia	74201|Verrucomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
DTH3_k127_807758_0	1123242.JH636434_gene4856	5.431e-202	643.0	COG0591@1|root,COG0591@2|Bacteria,2J2KC@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DTH3_k127_807758_2	1156935.QWE_19483	1.367e-92	315.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4B993@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	gluconolactonase	-	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
DTH3_k127_807758_6	1485544.JQKP01000003_gene284	1.002e-08	69.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
DTH3_k127_807758_4	497964.CfE428DRAFT_2297	1.164e-34	153.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH3_k127_807758_7	765914.ThisiDRAFT_1372	2.9e-06	55.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1WX3X@135613|Chromatiales	135613|Chromatiales	N	PFAM ABC-type uncharacterised transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
DTH3_k127_8093056_0	240016.ABIZ01000001_gene2706	6.668e-82	281.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH3_k127_8093056_3	483219.LILAB_15610	1.974e-08	68.0	COG2133@1|root,COG2133@2|Bacteria,1PEJE@1224|Proteobacteria,437VF@68525|delta/epsilon subdivisions,2X352@28221|Deltaproteobacteria,2YUAU@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,GSDH,Ig_3
DTH3_k127_8093056_2	661478.OP10G_2992	8.824e-13	78.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_8093056_1	945713.IALB_0846	6.427e-17	93.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,COG4733@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,Malectin,fn3
DTH3_k127_8093608_1	497964.CfE428DRAFT_6471	7.728e-173	550.0	COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DTH3_k127_8093608_2	521674.Plim_2636	4.165e-141	464.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
DTH3_k127_8093608_3	1111479.AXAR01000001_gene213	8.903e-62	222.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,278V8@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH3_k127_8093608_0	1396141.BATP01000006_gene5477	6.831e-219	697.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,46TDA@74201|Verrucomicrobia,2IV8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DTH3_k127_8098710_3	111781.Lepto7376_2051	1.804e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1H8XZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
DTH3_k127_8098710_2	1121405.dsmv_3253	6.169e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,1MZGK@1224|Proteobacteria,42US4@68525|delta/epsilon subdivisions,2X72T@28221|Deltaproteobacteria,2MPJC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
DTH3_k127_8098710_1	880073.Calab_0868	3.686e-15	87.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
DTH3_k127_8098710_0	575540.Isop_0569	1.264e-205	645.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_8098710_4	1452536.JARE01000052_gene1721	0.0001622	51.0	2EH4F@1|root,33AWE@2|Bacteria,2I6EJ@201174|Actinobacteria,4FTHX@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_810205_0	1267533.KB906735_gene4670	1.647e-210	674.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_8137971_0	485913.Krac_6798	3.962e-85	295.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
DTH3_k127_8137971_5	240016.ABIZ01000001_gene4454	3.381e-10	68.0	2BJXT@1|root,32EAA@2|Bacteria,46XIQ@74201|Verrucomicrobia,2IW0S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8137971_4	1340493.JNIF01000003_gene1913	2.072e-26	111.0	COG1846@1|root,COG1846@2|Bacteria,3Y7YY@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
DTH3_k127_8137971_1	497964.CfE428DRAFT_2012	8.805e-74	260.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
DTH3_k127_8137971_2	1396418.BATQ01000107_gene5393	6.506e-71	248.0	COG1633@1|root,COG1633@2|Bacteria,46VFF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8137971_3	234267.Acid_7735	3.6e-63	222.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
DTH3_k127_818292_1	497964.CfE428DRAFT_0118	1.167e-77	266.0	COG1972@1|root,COG1972@2|Bacteria,46S7I@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Na dependent nucleoside transporter domain protein	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
DTH3_k127_818292_3	118168.MC7420_6357	0.0001369	57.0	COG2730@1|root,COG2931@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,1G314@1117|Cyanobacteria,1HAD6@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Calx-beta,Glyco_hydro_9
DTH3_k127_818292_2	999411.HMPREF1092_02916	8.579e-24	120.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,24AUI@186801|Clostridia,36DY0@31979|Clostridiaceae	186801|Clostridia	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3794,SdrD_B
DTH3_k127_818292_0	864051.BurJ1DRAFT_3700	1.725e-112	412.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
DTH3_k127_8189287_4	335543.Sfum_3489	5.362e-17	87.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,1QU25@1224|Proteobacteria,42YRH@68525|delta/epsilon subdivisions,2WUGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
DTH3_k127_8189287_5	1238190.AMQY01000023_gene441	3.47e-14	84.0	COG2304@1|root,COG2304@2|Bacteria,1RGCN@1224|Proteobacteria,1S5GI@1236|Gammaproteobacteria,1XPSH@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
DTH3_k127_8189287_1	1121403.AUCV01000010_gene1377	1.299e-50	199.0	COG2885@1|root,COG3221@1|root,COG2885@2|Bacteria,COG3221@2|Bacteria,1R687@1224|Proteobacteria,42ZCB@68525|delta/epsilon subdivisions,2WTSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,OmpA
DTH3_k127_8189287_3	1120792.JAFV01000001_gene1790	8.432e-29	128.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
DTH3_k127_8189287_2	316056.RPC_4535	4.994e-44	171.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TTR3@28211|Alphaproteobacteria,3JR5N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
DTH3_k127_8196037_1	1123392.AQWL01000008_gene1217	8.51e-15	79.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,1KSKF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
DTH3_k127_8196037_0	335543.Sfum_1859	5.551e-213	685.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,42Q50@68525|delta/epsilon subdivisions,2WJN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8219557_2	886293.Sinac_2090	1.742e-15	80.0	COG0823@1|root,COG0823@2|Bacteria,2IZ00@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
DTH3_k127_8219557_3	1121468.AUBR01000005_gene35	3.851e-11	73.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,42H0N@68295|Thermoanaerobacterales	186801|Clostridia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
DTH3_k127_8219557_0	382464.ABSI01000006_gene864	1.118e-162	519.0	COG1225@1|root,COG1225@2|Bacteria,46TJA@74201|Verrucomicrobia,2ITIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH3_k127_8219557_6	866771.HMPREF9296_1795	4.144e-07	64.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
DTH3_k127_8219557_5	56780.SYN_03067	2.078e-09	65.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SmpA_OmlA,SusD-like_3
DTH3_k127_8219557_1	323259.Mhun_0476	1.067e-63	228.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
DTH3_k127_822078_0	309801.trd_0861	1.666e-82	284.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,27XK0@189775|Thermomicrobia	189775|Thermomicrobia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DTH3_k127_822078_1	1519464.HY22_08455	9.565e-68	235.0	COG0225@1|root,COG0225@2|Bacteria,1FE4X@1090|Chlorobi	1090|Chlorobi	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
DTH3_k127_8235383_1	326297.Sama_0303	1.731e-73	255.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T3ZW@1236|Gammaproteobacteria,2QEVF@267890|Shewanellaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH3_k127_8235383_0	452637.Oter_0253	5.885e-147	474.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
DTH3_k127_8235383_2	1123229.AUBC01000001_gene1837	3.624e-35	143.0	2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,2U8C9@28211|Alphaproteobacteria,3JZ9V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8235383_3	247490.KSU1_C0049	1.232e-27	116.0	COG1055@1|root,COG1055@2|Bacteria,2IXNR@203682|Planctomycetes	203682|Planctomycetes	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
DTH3_k127_8244171_2	1449351.RISW2_05860	7.168e-28	119.0	COG1863@1|root,COG1863@2|Bacteria,1Q85M@1224|Proteobacteria,2VEBF@28211|Alphaproteobacteria,4KNV3@93682|Roseivivax	28211|Alphaproteobacteria	P	Na+/H+ ion antiporter subunit	-	-	-	-	-	-	-	-	-	-	-	-	MNHE
DTH3_k127_8244171_1	240016.ABIZ01000001_gene1717	1.852e-48	179.0	COG0530@1|root,COG0530@2|Bacteria,46VFM@74201|Verrucomicrobia,2IUCD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
DTH3_k127_8244171_0	395019.Bmul_5567	4.256e-127	414.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
DTH3_k127_8249688_2	694431.DESACE_01260	4.335e-144	466.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2M6DK@213113|Desulfurellales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
DTH3_k127_8249688_3	497964.CfE428DRAFT_0527	1.399e-48	178.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
DTH3_k127_8249688_4	946077.W5A_01680	7.989e-16	88.0	2E35R@1|root,32Y5N@2|Bacteria,4P5KG@976|Bacteroidetes,1IAK3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8249688_0	497964.CfE428DRAFT_0527	1.197e-197	626.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
DTH3_k127_8249688_5	1395587.P364_0100010	3.122e-15	78.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178,HTH_OrfB_IS605
DTH3_k127_8249688_1	497964.CfE428DRAFT_0528	2.106e-149	488.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,46S6S@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
DTH3_k127_8257744_1	756272.Plabr_1201	8.982e-56	205.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
DTH3_k127_8257744_0	497964.CfE428DRAFT_4557	9.763e-191	606.0	COG2133@1|root,COG2133@2|Bacteria,46U0G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8257744_2	661478.OP10G_4109	6.881e-14	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_8264159_0	665571.STHERM_c16620	5.125e-25	121.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
DTH3_k127_8264725_1	391603.FBALC1_09677	1.05e-21	109.0	COG2706@1|root,COG4886@1|root,COG2706@2|Bacteria,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH3_k127_8264725_0	1499967.BAYZ01000068_gene1988	4.182e-35	148.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_8274610_0	497964.CfE428DRAFT_6644	9.251e-241	762.0	COG1657@1|root,COG1657@2|Bacteria,46TK5@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	sqhC	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
DTH3_k127_8281569_1	1178825.ALIH01000004_gene2807	8.75e-126	415.0	COG3408@1|root,COG5520@1|root,COG3408@2|Bacteria,COG5520@2|Bacteria,4NM34@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl hydrolase family 59	-	-	3.2.1.46	ko:K01202	ko00600,ko01100,ko04142,map00600,map01100,map04142	-	R03617	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH59	-	Glyco_hydro_59
DTH3_k127_8281569_0	1235803.C825_01953	4.036e-212	690.0	COG0639@1|root,COG0639@2|Bacteria,4NZWK@976|Bacteroidetes,2FPXD@200643|Bacteroidia	976|Bacteroidetes	T	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
DTH3_k127_828687_1	240016.ABIZ01000001_gene4678	6.842e-117	389.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,2ITVG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
DTH3_k127_828687_6	497964.CfE428DRAFT_4116	5.587e-16	87.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH3_k127_828687_7	102125.Xen7305DRAFT_00008790	4.08e-08	59.0	2CRRJ@1|root,32SPH@2|Bacteria,1GGJ1@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
DTH3_k127_828687_5	215803.DB30_7168	3.327e-17	93.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
DTH3_k127_828687_0	429009.Adeg_1724	2.547e-123	405.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH3_k127_828687_3	404589.Anae109_3433	1.533e-98	335.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DTH3_k127_828687_4	1123401.JHYQ01000006_gene6	2.961e-29	126.0	COG1432@1|root,COG1432@2|Bacteria,1REF0@1224|Proteobacteria,1S545@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
DTH3_k127_828687_2	696747.NIES39_E02730	5.309e-114	386.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
DTH3_k127_8297723_2	497964.CfE428DRAFT_1804	1.232e-19	91.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH3_k127_8297723_0	497964.CfE428DRAFT_5731	4.263e-61	220.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_8297723_1	1396141.BATP01000028_gene2285	5.188e-51	207.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
DTH3_k127_8297723_3	1120954.ATXE01000003_gene303	7.039e-15	89.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4DP00@85009|Propionibacteriales	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DTH3_k127_8307240_0	1396141.BATP01000060_gene4560	1.145e-155	516.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
DTH3_k127_8307240_2	1123242.JH636435_gene2613	3.537e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
DTH3_k127_8307240_1	1123242.JH636434_gene3764	4.455e-97	329.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_8307440_0	269799.Gmet_1302	1.119e-93	313.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
DTH3_k127_8307440_4	1156937.MFUM_200030	6.367e-20	93.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,37HAT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	PurA ssDNA and RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PurA
DTH3_k127_8307440_3	237368.SCABRO_02951	4.18e-29	121.0	COG0799@1|root,COG0799@2|Bacteria,2J0AM@203682|Planctomycetes	203682|Planctomycetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
DTH3_k127_8307440_2	452637.Oter_1760	6.265e-43	163.0	COG1057@1|root,COG1057@2|Bacteria,46T27@74201|Verrucomicrobia,3K85U@414999|Opitutae	414999|Opitutae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DTH3_k127_8307440_1	1267535.KB906767_gene4931	6.12e-82	276.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria,2JI52@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
DTH3_k127_8331673_1	1244869.H261_12401	1.235e-48	183.0	COG1410@1|root,COG1410@2|Bacteria,1NSVT@1224|Proteobacteria	1224|Proteobacteria	E	Pterin binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
DTH3_k127_8331673_0	555088.DealDRAFT_2480	1.022e-234	736.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,42JKP@68298|Syntrophomonadaceae	186801|Clostridia	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
DTH3_k127_833557_2	497964.CfE428DRAFT_2487	6.661e-40	162.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
DTH3_k127_833557_3	102129.Lepto7375DRAFT_7777	5.429e-13	80.0	COG0457@1|root,COG0714@1|root,COG0457@2|Bacteria,COG0714@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
DTH3_k127_833557_1	240016.ABIZ01000001_gene3134	2.199e-67	245.0	COG0628@1|root,COG0628@2|Bacteria,46VTV@74201|Verrucomicrobia,2ITP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DTH3_k127_833557_0	1123242.JH636436_gene439	1.426e-83	285.0	COG0345@1|root,COG0345@2|Bacteria,2IY5U@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
DTH3_k127_8337004_0	452637.Oter_2196	8.899e-185	590.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_8337004_1	1267535.KB906767_gene3674	1.644e-130	425.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	MA20_02630	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_8337004_2	555079.Toce_1809	9.537e-55	204.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
DTH3_k127_8338068_0	1097668.BYI23_C006580	7.456e-84	292.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
DTH3_k127_8375791_1	886293.Sinac_6489	5.834e-121	406.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
DTH3_k127_8375791_3	497964.CfE428DRAFT_0545	5.599e-54	198.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_8375791_4	641524.ADICYQ_2834	1.828e-06	51.0	COG2610@1|root,COG2610@2|Bacteria,4NJ5B@976|Bacteroidetes,47K2S@768503|Cytophagia	976|Bacteroidetes	EG	PFAM Gluconate transporter	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
DTH3_k127_8375791_0	401526.TcarDRAFT_0709	4.017e-220	691.0	COG4948@1|root,COG4948@2|Bacteria,1TUWS@1239|Firmicutes,4H2CE@909932|Negativicutes	909932|Negativicutes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DTH3_k127_8375791_2	1340493.JNIF01000004_gene737	2.246e-80	278.0	COG0329@1|root,COG0329@2|Bacteria,3Y7AU@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100	-	R02279	RC00678	ko00000,ko00001,ko01000	-	-	-	DHDPS
DTH3_k127_8381329_0	452637.Oter_0691	7.74e-100	333.0	COG0548@1|root,COG0548@2|Bacteria,46SH9@74201|Verrucomicrobia,3K7U8@414999|Opitutae	414999|Opitutae	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DTH3_k127_8381329_3	314230.DSM3645_29826	1.371e-08	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_8381329_1	756272.Plabr_0281	3.138e-11	72.0	COG4968@1|root,COG4968@2|Bacteria,2J53J@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_8381329_2	344747.PM8797T_28619	1.158e-09	67.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_8385451_2	1185876.BN8_00946	4.426e-47	177.0	COG0823@1|root,COG0823@2|Bacteria,4NYXJ@976|Bacteroidetes	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH3_k127_8385451_3	926550.CLDAP_31990	3.768e-40	160.0	COG1082@1|root,COG1082@2|Bacteria,2G7PW@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_8385451_0	1267533.KB906739_gene2717	2.332e-232	740.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid_C,Bgal_small_N,Glyco_hydro_2,Glyco_hydro_28,Glyco_hydro_2_C,Glyco_hydro_2_N,fn3
DTH3_k127_8385451_1	616991.JPOO01000003_gene29	3.749e-100	341.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DTH3_k127_8387123_1	696369.KI912183_gene1481	1.804e-99	334.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DTH3_k127_8387123_2	794903.OPIT5_16130	7.436e-93	314.0	COG1028@1|root,COG1028@2|Bacteria,46TD2@74201|Verrucomicrobia,3K7W5@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH3_k127_8387123_0	33876.JNXY01000025_gene5296	4.426e-196	621.0	COG4225@1|root,COG4225@2|Bacteria,2I2TJ@201174|Actinobacteria,4DGGH@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
DTH3_k127_8387123_3	497964.CfE428DRAFT_6195	1.618e-19	90.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_8391955_13	370438.PTH_1110	5.991e-32	140.0	COG1388@1|root,COG1388@2|Bacteria,1VJ2T@1239|Firmicutes,24YEF@186801|Clostridia,264FH@186807|Peptococcaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8391955_4	1454007.JAUG01000047_gene512	3.71e-166	535.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_8391955_15	1395587.P364_0117575	2.164e-25	114.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DTH3_k127_8391955_7	240016.ABIZ01000001_gene1086	5.086e-89	300.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,2IU40@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DTH3_k127_8391955_6	382464.ABSI01000011_gene2675	2.458e-116	392.0	COG2610@1|root,COG2610@2|Bacteria,46UQS@74201|Verrucomicrobia,2IVYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
DTH3_k127_8391955_11	1123508.JH636439_gene1058	2.679e-49	184.0	COG4221@1|root,COG4221@2|Bacteria,2IYVR@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH3_k127_8391955_3	497964.CfE428DRAFT_0139	3.002e-176	557.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_8391955_0	1123242.JH636434_gene3346	0.0	1187.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
DTH3_k127_8391955_1	1396418.BATQ01000142_gene3267	6.123e-218	685.0	COG3119@1|root,COG3119@2|Bacteria,46Z2W@74201|Verrucomicrobia,2IWNY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_8391955_12	269482.Bcep1808_5363	4.941e-47	173.0	COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,2WGHN@28216|Betaproteobacteria,1K7F9@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
DTH3_k127_8391955_8	1403819.BATR01000017_gene538	6.737e-57	202.0	COG1764@1|root,COG1764@2|Bacteria,46VXJ@74201|Verrucomicrobia,2IW5Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DTH3_k127_8391955_10	1123508.JH636443_gene5018	2.819e-51	187.0	COG3324@1|root,COG3324@2|Bacteria,2J3W8@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
DTH3_k127_8391955_14	1396141.BATP01000059_gene2546	8.142e-28	118.0	2CIV9@1|root,34A52@2|Bacteria,46W0H@74201|Verrucomicrobia,2IUYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
DTH3_k127_8391955_2	1403819.BATR01000191_gene6501	1.21e-212	671.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
DTH3_k127_8391955_5	1122605.KB893648_gene3690	1.091e-149	497.0	28J61@1|root,2Z91S@2|Bacteria,4NKJU@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
DTH3_k127_8391955_9	742725.HMPREF9450_01131	1.971e-51	187.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,2FPEC@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
DTH3_k127_8401701_4	251229.Chro_1157	3.195e-67	234.0	COG1905@1|root,COG1905@2|Bacteria,1G54V@1117|Cyanobacteria,3VJR9@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
DTH3_k127_8401701_0	98439.AJLL01000016_gene1689	6.789e-254	793.0	COG1894@1|root,COG1894@2|Bacteria,1G2KY@1117|Cyanobacteria	1117|Cyanobacteria	C	NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit	hoxF	-	1.6.5.3	ko:K05587	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
DTH3_k127_8401701_2	1173028.ANKO01000017_gene242	7.228e-107	350.0	COG3383@1|root,COG3383@2|Bacteria,1G3GD@1117|Cyanobacteria,1H7Z2@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	hoxU	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3
DTH3_k127_8401701_3	1173028.ANKO01000017_gene241	3.267e-70	249.0	COG1941@1|root,COG1941@2|Bacteria,1G2I6@1117|Cyanobacteria,1H9X3@1150|Oscillatoriales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, gamma subunit	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	iJN678.hoxY	Oxidored_q6
DTH3_k127_8401701_1	28072.Nos7524_1733	2.891e-203	642.0	COG3259@1|root,COG3259@2|Bacteria,1G1C8@1117|Cyanobacteria,1HMGB@1161|Nostocales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, alpha subunit	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	iJN678.hoxH	NiFeSe_Hases
DTH3_k127_8413857_0	344747.PM8797T_32040	8.619e-205	673.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
DTH3_k127_8413857_8	504472.Slin_2680	3.678e-35	147.0	COG2133@1|root,COG3291@1|root,COG4625@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
DTH3_k127_8413857_7	344747.PM8797T_31653	9.922e-58	217.0	2F8GG@1|root,340VA@2|Bacteria,2J3K0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8413857_2	344747.PM8797T_31648	2.839e-110	371.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	tagS	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_8413857_5	344747.PM8797T_31643	6.066e-75	259.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003,ko:K05685,ko:K09810	ko02010,map02010	M00255,M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12,3.A.1.125	-	-	ABC_tran
DTH3_k127_8413857_1	344747.PM8797T_31638	3.242e-143	471.0	COG0725@1|root,COG0725@2|Bacteria,2J08C@203682|Planctomycetes	203682|Planctomycetes	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
DTH3_k127_8413857_4	344747.PM8797T_31633	2.475e-95	323.0	COG0555@1|root,COG0555@2|Bacteria,2IYJ3@203682|Planctomycetes	203682|Planctomycetes	O	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
DTH3_k127_8413857_6	344747.PM8797T_31628	3.187e-71	247.0	COG3842@1|root,COG3842@2|Bacteria,2IZ85@203682|Planctomycetes	203682|Planctomycetes	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH3_k127_8413857_3	344747.PM8797T_31618	4.892e-104	352.0	COG0476@1|root,COG0476@2|Bacteria,2IY5K@203682|Planctomycetes	203682|Planctomycetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
DTH3_k127_8413857_9	1396141.BATP01000060_gene4727	1.884e-05	48.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
DTH3_k127_8420925_4	1156937.MFUM_230006	6.664e-64	228.0	COG1956@1|root,COG2203@1|root,COG4191@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,37G69@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
DTH3_k127_8420925_7	497964.CfE428DRAFT_0221	2.404e-39	154.0	2EKW2@1|root,33EJK@2|Bacteria,46VZV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8420925_5	1403819.BATR01000031_gene1028	2.462e-61	220.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
DTH3_k127_8420925_1	1031288.AXAA01000009_gene666	7.818e-168	548.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
DTH3_k127_8420925_3	497964.CfE428DRAFT_4748	2.6e-95	319.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH3_k127_8420925_0	452637.Oter_3558	3.615e-250	779.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH3_k127_8420925_2	1403819.BATR01000125_gene4494	5.77e-145	492.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DTH3_k127_8429452_0	1449126.JQKL01000015_gene2921	1.257e-137	449.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,26865@186813|unclassified Clostridiales	186801|Clostridia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DTH3_k127_8429452_1	478741.JAFS01000002_gene378	0.0003029	50.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,37G9U@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
DTH3_k127_8431312_0	497964.CfE428DRAFT_5033	1.539e-48	174.0	COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8431312_1	497964.CfE428DRAFT_0111	3.678e-23	115.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8433324_6	243233.MCA2830	6.999e-15	78.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
DTH3_k127_8433324_1	1510531.JQJJ01000010_gene2441	4.226e-118	396.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2V9SJ@28211|Alphaproteobacteria,3JRUA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Amino acid permease	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH3_k127_8433324_8	765913.ThidrDRAFT_2565	1.426e-06	51.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria,1WWGX@135613|Chromatiales	135613|Chromatiales	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH3_k127_8433324_3	1454004.AW11_00497	4.148e-93	316.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DTH3_k127_8433324_0	595536.ADVE02000001_gene3060	9.93e-211	687.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,36Z5E@31993|Methylocystaceae	28211|Alphaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
DTH3_k127_8433324_2	926550.CLDAP_33840	1.17e-109	364.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DTH3_k127_8433324_4	521674.Plim_2940	1.118e-72	252.0	COG1387@1|root,COG1387@2|Bacteria,2IZCF@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_8433324_5	1304888.ATWF01000001_gene1502	2.584e-28	116.0	COG1335@1|root,COG1335@2|Bacteria,2GFP3@200930|Deferribacteres	200930|Deferribacteres	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
DTH3_k127_8444407_1	1217710.F969_01164	4.326e-20	93.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,3NKKZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
DTH3_k127_8444407_2	270374.MELB17_22515	4.664e-12	72.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1T7KM@1236|Gammaproteobacteria,46C37@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8444407_0	1172188.KB911820_gene2633	5.119e-221	693.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FG4H@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH3_k127_8449397_0	1396141.BATP01000003_gene4934	1.085e-165	567.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
DTH3_k127_8457957_1	497964.CfE428DRAFT_4695	1.698e-126	440.0	COG1196@1|root,COG1196@2|Bacteria,46TT8@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DTH3_k127_8457957_3	391625.PPSIR1_09091	9.497e-12	77.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
DTH3_k127_8457957_0	452637.Oter_2475	1.756e-253	794.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,3K79T@414999|Opitutae	414999|Opitutae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DTH3_k127_8457957_2	1267535.KB906767_gene5199	1.845e-50	182.0	COG1082@1|root,COG1082@2|Bacteria,3Y78R@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_8468367_6	1173028.ANKO01000018_gene1201	2.623e-16	93.0	COG1404@1|root,COG2931@1|root,COG3210@1|root,COG3940@1|root,COG4447@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3940@2|Bacteria,COG4447@2|Bacteria,1G4T5@1117|Cyanobacteria,1HHYV@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,Haemagg_act,HemolysinCabind
DTH3_k127_8468367_3	247634.GPB2148_909	2.086e-75	264.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1J6J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Microcin C7 resistance	ldcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641	Peptidase_S66
DTH3_k127_8468367_7	661478.OP10G_2992	3.044e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_8468367_0	118168.MC7420_4981	2.437e-186	612.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DTH3_k127_8468367_4	1121441.AUCX01000016_gene2382	1.256e-42	180.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,42RTP@68525|delta/epsilon subdivisions,2WN9M@28221|Deltaproteobacteria,2M9XH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_8,Response_reg,SpoIIE
DTH3_k127_8468367_1	240016.ABIZ01000001_gene2661	1.337e-171	543.0	COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH3_k127_8468367_2	344747.PM8797T_00347	3.063e-123	407.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
DTH3_k127_8468367_5	278957.ABEA03000157_gene660	7.832e-18	84.0	COG0442@1|root,COG0442@2|Bacteria,46UF8@74201|Verrucomicrobia,3K7AQ@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
DTH3_k127_8475663_0	497964.CfE428DRAFT_4166	1.483e-151	494.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DTH3_k127_8475663_1	497964.CfE428DRAFT_5925	5.167e-57	208.0	COG0125@1|root,COG0125@2|Bacteria,46ST1@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DTH3_k127_8475663_2	909663.KI867150_gene972	8.011e-26	109.0	2CIE9@1|root,32S7U@2|Bacteria,1P112@1224|Proteobacteria,431TX@68525|delta/epsilon subdivisions,2WWP3@28221|Deltaproteobacteria,2MS3R@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
DTH3_k127_8487370_0	1210884.HG799465_gene12146	1.214e-141	462.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_8492980_4	635013.TherJR_2042	3.607e-25	112.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DTH3_k127_8492980_3	497964.CfE428DRAFT_6522	4.836e-39	156.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
DTH3_k127_8492980_1	497964.CfE428DRAFT_5454	5.1e-64	233.0	COG0122@1|root,COG0122@2|Bacteria,46SVK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	8-oxoguanine DNA glycosylase, N-terminal domain	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
DTH3_k127_8492980_2	1396141.BATP01000057_gene2980	6.208e-56	201.0	COG0503@1|root,COG0503@2|Bacteria,46SV8@74201|Verrucomicrobia,2IUHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
DTH3_k127_8492980_0	497964.CfE428DRAFT_4839	1.958e-115	378.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DTH3_k127_8509634_0	1123242.JH636434_gene5339	9.342e-168	534.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_8509634_1	1123242.JH636434_gene5340	2.868e-113	390.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_8509634_2	192952.MM_3198	4.399e-40	151.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
DTH3_k127_8510229_2	234267.Acid_0995	1.364e-06	57.0	COG3391@1|root,COG3391@2|Bacteria,3Y7I2@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8510229_0	929562.Emtol_1205	6.686e-111	364.0	COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes,47KN3@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DTH3_k127_8510229_1	452637.Oter_1726	4.839e-55	200.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	2|Bacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
DTH3_k127_8514019_4	945713.IALB_3143	6.344e-60	209.0	COG0229@1|root,COG0229@2|Bacteria	2|Bacteria	O	peptide-methionine (R)-S-oxide reductase activity	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DTH3_k127_8514019_10	203119.Cthe_3006	0.0002602	51.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1V9XU@1239|Firmicutes,24NW6@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
DTH3_k127_8514019_0	471853.Bcav_3390	6.464e-132	443.0	COG2730@1|root,COG3537@1|root,COG4225@1|root,COG2730@2|Bacteria,COG3537@2|Bacteria,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,F5_F8_type_C,Hepar_II_III,Ricin_B_lectin
DTH3_k127_8514019_3	497964.CfE428DRAFT_6252	2.297e-82	285.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DTH3_k127_8514019_1	497964.CfE428DRAFT_1213	7.016e-105	351.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	DUF4388,HATPase_c,HTH_8,HisKA,Response_reg,SSF,Sigma54_activat
DTH3_k127_8514019_2	497964.CfE428DRAFT_1215	7.589e-95	316.0	COG1100@1|root,COG1100@2|Bacteria,46VDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	Arf
DTH3_k127_8514019_8	497964.CfE428DRAFT_1216	8.747e-31	127.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
DTH3_k127_8514019_9	1312959.KI914674_gene3398	6.381e-06	59.0	COG3087@1|root,COG3291@1|root,COG3087@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria	201174|Actinobacteria	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Laminin_G_3,PKD
DTH3_k127_8514019_5	1396141.BATP01000060_gene4657	1.499e-40	172.0	COG2010@1|root,COG2312@1|root,COG3204@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD,Laminin_G_3
DTH3_k127_8531691_1	497964.CfE428DRAFT_3460	2.828e-77	273.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46SP8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
DTH3_k127_8531691_0	497964.CfE428DRAFT_3459	6.184e-98	331.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
DTH3_k127_8531691_2	237368.SCABRO_01881	8.316e-23	107.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8549017_0	589865.DaAHT2_2431	1.785e-148	482.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2X5QK@28221|Deltaproteobacteria,2MPFP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
DTH3_k127_8549017_1	1196323.ALKF01000152_gene1018	1.586e-26	117.0	2C4H4@1|root,32X9D@2|Bacteria,1VCB6@1239|Firmicutes,4HKJT@91061|Bacilli,26TSY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8549017_2	1035191.HMPREF0185_02470	9.981e-05	49.0	COG1357@1|root,COG1357@2|Bacteria,1RFRV@1224|Proteobacteria,2U7UC@28211|Alphaproteobacteria,2KIYC@204458|Caulobacterales	204458|Caulobacterales	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
DTH3_k127_8554214_3	1288494.EBAPG3_19800	2.026e-18	87.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,2WB4B@28216|Betaproteobacteria,372A6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_8554214_4	338963.Pcar_1313	1.103e-10	76.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
DTH3_k127_8554214_0	1396141.BATP01000030_gene3746	1.317e-229	721.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH3_k127_8554214_1	497964.CfE428DRAFT_3050	2.634e-130	424.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
DTH3_k127_8554214_2	497964.CfE428DRAFT_3049	4.046e-126	407.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10559,ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2,Peripla_BP_4
DTH3_k127_855748_2	1403819.BATR01000162_gene5417	4.249e-92	313.0	COG2010@1|root,COG2133@1|root,COG3291@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,46U71@74201|Verrucomicrobia,2IVDV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Laminin_G_3
DTH3_k127_855748_1	1173026.Glo7428_4012	2.488e-148	486.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
DTH3_k127_855748_6	1182553.XP_007740985.1	1.858e-14	87.0	2EX73@1|root,2SYX9@2759|Eukaryota,3A366@33154|Opisthokonta,3P2YI@4751|Fungi,3QU7S@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_855748_7	102232.GLO73106DRAFT_00036360	2.546e-08	67.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5122,FG-GAP,HemolysinCabind
DTH3_k127_855748_0	237368.SCABRO_00954	5.296e-191	609.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
DTH3_k127_855748_8	243233.MCA2974	0.0001132	55.0	COG3291@1|root,COG5563@1|root,COG3291@2|Bacteria,COG5563@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria,1XGBG@135618|Methylococcales	135618|Methylococcales	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_855748_5	1123242.JH636435_gene1741	9.033e-16	88.0	COG2165@1|root,COG2165@2|Bacteria,2IYZV@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_855748_4	1303518.CCALI_02493	3.22e-18	94.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_855748_3	349741.Amuc_1233	1.289e-21	94.0	COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia,2IUS9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
DTH3_k127_8570549_0	452637.Oter_1456	1.448e-82	293.0	COG1538@1|root,COG1538@2|Bacteria,46TY1@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH3_k127_8570549_1	1056820.KB900646_gene3544	5.229e-20	92.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,2PQGZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DTH3_k127_8570549_4	1168289.AJKI01000035_gene3570	5.528e-12	68.0	2AD45@1|root,312SH@2|Bacteria,4PHQV@976|Bacteroidetes,2G1PE@200643|Bacteroidia,3XKFZ@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8570549_2	926566.Terro_2606	4.368e-19	90.0	COG0640@1|root,COG0640@2|Bacteria,3Y5UV@57723|Acidobacteria,2JNP2@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DTH3_k127_8570549_3	1303518.CCALI_00933	5.321e-12	76.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
DTH3_k127_8572308_4	497964.CfE428DRAFT_5082	8.585e-08	54.0	COG5267@1|root,COG5267@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800,SLH
DTH3_k127_8572308_0	497964.CfE428DRAFT_5081	1.017e-149	488.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
DTH3_k127_8572308_1	497964.CfE428DRAFT_5080	2.038e-26	117.0	29N11@1|root,344HT@2|Bacteria,46WBB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8572308_3	452637.Oter_2961	1.939e-15	79.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	e_coli_core.b2415,iAF1260.b2415,iB21_1397.B21_02276,iBWG_1329.BWG_2177,iE2348C_1286.E2348C_2601,iEC042_1314.EC042_2624,iEC55989_1330.EC55989_2705,iECABU_c1320.ECABU_c27360,iECBD_1354.ECBD_1266,iECB_1328.ECB_02315,iECDH10B_1368.ECDH10B_2580,iECDH1ME8569_1439.ECDH1ME8569_2349,iECDH1ME8569_1439.EcDH1_1246,iECD_1391.ECD_02315,iECED1_1282.ECED1_2859,iECH74115_1262.ECH74115_3646,iECIAI1_1343.ECIAI1_2473,iECIAI39_1322.ECIAI39_2561,iECNA114_1301.ECNA114_2492,iECO103_1326.ECO103_2934,iECO111_1330.ECO111_3145,iECO26_1355.ECO26_3468,iECOK1_1307.ECOK1_2732,iECP_1309.ECP_2439,iECS88_1305.ECS88_2605,iECSE_1348.ECSE_2706,iECSF_1327.ECSF_2279,iECSP_1301.ECSP_3363,iECUMN_1333.ECUMN_2737,iECW_1372.ECW_m2644,iECs_1301.ECs3287,iEKO11_1354.EKO11_1313,iETEC_1333.ETEC_2528,iEcDH1_1363.EcDH1_1246,iEcE24377_1341.EcE24377A_2702,iEcHS_1320.EcHS_A2550,iEcSMS35_1347.EcSMS35_2570,iEcolC_1368.EcolC_1263,iG2583_1286.G2583_2947,iJO1366.b2415,iJR904.b2415,iLF82_1304.LF82_1769,iNRG857_1313.NRG857_12110,iPC815.YPO2993,iSBO_1134.SBO_2439,iSDY_1059.SDY_2612,iSFV_1184.SFV_2467,iSF_1195.SF2470,iSFxv_1172.SFxv_2719,iSSON_1240.SSON_2504,iS_1188.S2616,iSbBS512_1146.SbBS512_E2765,iUMN146_1321.UM146_04545,iUMNK88_1353.UMNK88_3017,iUTI89_1310.UTI89_C2749,iWFL_1372.ECW_m2644,iY75_1357.Y75_RS12655,iZ_1308.Z3681,ic_1306.c2950	PTS-HPr
DTH3_k127_8572308_2	331678.Cphamn1_0275	3.417e-20	98.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DTH3_k127_8583068_1	530564.Psta_4256	1.195e-25	112.0	COG2010@1|root,COG2133@1|root,COG3474@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DTH3_k127_8583068_0	1158292.JPOE01000002_gene3555	5.939e-46	171.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH3_k127_8583068_3	1320556.AVBP01000012_gene3576	0.0001808	48.0	COG0342@1|root,COG0342@2|Bacteria,1NRIJ@1224|Proteobacteria,2UPCM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8583068_2	1210884.HG799465_gene12104	3.593e-16	91.0	2BRCH@1|root,32KB5@2|Bacteria,2J2TZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8585865_1	1089547.KB913013_gene3400	2.23e-11	77.0	COG1874@1|root,COG2133@1|root,COG1874@2|Bacteria,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
DTH3_k127_8585865_0	1280390.CBQR020000048_gene957	1.214e-32	145.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
DTH3_k127_8589392_0	997884.HMPREF1068_02702	4.654e-247	810.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,4AP3C@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
DTH3_k127_8592073_1	794903.OPIT5_05580	2.242e-24	110.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,3K87P@414999|Opitutae	414999|Opitutae	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
DTH3_k127_8592073_0	497964.CfE428DRAFT_0417	6.949e-85	291.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DTH3_k127_860490_3	118173.KB235914_gene1471	0.000192	52.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1HAPX@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
DTH3_k127_860490_4	497964.CfE428DRAFT_0660	0.0007884	49.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1542,DUF349,DUF4446,FIVAR,GA,Gram_pos_anchor,PhageMin_Tail
DTH3_k127_860490_0	1156937.MFUM_270037	4.083e-51	194.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,37GE7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_16,TPR_6,YfiO
DTH3_k127_860490_2	497964.CfE428DRAFT_3831	1.861e-16	88.0	2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
DTH3_k127_860490_1	497964.CfE428DRAFT_4502	1.321e-18	89.0	COG0607@1|root,COG0607@2|Bacteria,46W9V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DTH3_k127_8605313_1	903818.KI912269_gene546	1.656e-89	299.0	COG0722@1|root,COG0722@2|Bacteria,3Y2HE@57723|Acidobacteria	57723|Acidobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
DTH3_k127_8605313_0	497964.CfE428DRAFT_3486	0.0	1579.0	COG1038@1|root,COG1038@2|Bacteria,46S8N@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Conserved carboxylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
DTH3_k127_8607052_1	926569.ANT_25430	1.239e-94	326.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
DTH3_k127_8607052_3	1125863.JAFN01000001_gene83	4.272e-50	186.0	COG2020@1|root,COG2020@2|Bacteria,1RBUU@1224|Proteobacteria,42UT0@68525|delta/epsilon subdivisions,2WQKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
DTH3_k127_8607052_4	452637.Oter_1440	3.565e-08	57.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
DTH3_k127_8607052_2	926566.Terro_3682	3.094e-51	190.0	COG2152@1|root,COG2152@2|Bacteria,3Y5H3@57723|Acidobacteria,2JM4K@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_8607052_0	497964.CfE428DRAFT_2154	3.671e-160	515.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DTH3_k127_8616288_1	240016.ABIZ01000001_gene3537	5.355e-144	477.0	COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
DTH3_k127_8616288_5	1214217.ALNF01000014_gene1478	5.664e-05	53.0	COG3944@1|root,COG3944@2|Bacteria,1V4ZF@1239|Firmicutes,4IR4A@91061|Bacilli,1WSAY@1307|Streptococcus suis	91061|Bacilli	M	Chain length determinant protein	cps4C	-	-	-	-	-	-	-	-	-	-	-	Wzz
DTH3_k127_8616288_4	497321.C664_02540	4.8e-08	55.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VK17@28216|Betaproteobacteria,2KY4N@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DTH3_k127_8616288_2	313590.MED134_09431	2.938e-97	326.0	COG2374@1|root,COG2374@2|Bacteria,4NI8T@976|Bacteroidetes,1I0TH@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
DTH3_k127_8616288_0	1519464.HY22_10360	2.135e-191	614.0	COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
DTH3_k127_8616288_3	1279009.ADICEAN_02097	1.774e-30	124.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8617295_0	497964.CfE428DRAFT_1455	1.214e-204	646.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
DTH3_k127_8617295_1	497964.CfE428DRAFT_1451	4.312e-136	446.0	COG1459@1|root,COG1459@2|Bacteria,46S8P@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	type II secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DTH3_k127_8617295_3	1396418.BATQ01000166_gene1838	2.285e-23	102.0	2FCWX@1|root,344ZT@2|Bacteria,46WDE@74201|Verrucomicrobia,2IUVW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
DTH3_k127_8617295_2	497964.CfE428DRAFT_6148	4.236e-28	115.0	2DTD6@1|root,33JTS@2|Bacteria,46WA4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
DTH3_k127_8617295_4	1210884.HG799475_gene15301	3.288e-06	57.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_8617295_5	1403819.BATR01000181_gene6136	6.991e-05	54.0	COG4968@1|root,COG4968@2|Bacteria,46WJ1@74201|Verrucomicrobia,2IUWN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DTH3_k127_8617295_6	211586.SO_0853	0.0003834	51.0	COG4970@1|root,COG4970@2|Bacteria,1PC9R@1224|Proteobacteria,1SX5Y@1236|Gammaproteobacteria,2QCSM@267890|Shewanellaceae	1236|Gammaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
DTH3_k127_8618433_4	344747.PM8797T_11666	2.607e-56	209.0	COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_8618433_5	1120971.AUCA01000003_gene1386	8.614e-22	99.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,27A9H@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix gluconate operon transcriptional repressor	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
DTH3_k127_8618433_1	497964.CfE428DRAFT_5037	3.561e-141	462.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
DTH3_k127_8618433_2	768671.ThimaDRAFT_3418	8.019e-78	271.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WXRA@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DTH3_k127_8618433_0	497964.CfE428DRAFT_6179	6.673e-171	561.0	COG3875@1|root,COG3875@2|Bacteria,46TVY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
DTH3_k127_8618433_3	325452.fgenesh_scip_prom.46568.7654	3.228e-67	231.0	COG0318@1|root,COG0590@1|root,KOG1018@2759|Eukaryota,KOG1176@2759|Eukaryota,3Q9PC@4776|Peronosporales	4776|Peronosporales	I	AMP-binding enzyme C-terminal domain	-	-	-	ko:K18660	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
DTH3_k127_8619146_4	1380394.JADL01000003_gene4962	3.908e-26	110.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
DTH3_k127_8619146_3	944479.JQLX01000016_gene325	3.049e-28	119.0	COG2050@1|root,COG2050@2|Bacteria,1N8F8@1224|Proteobacteria,42V78@68525|delta/epsilon subdivisions,2WRBA@28221|Deltaproteobacteria,2M7BC@213113|Desulfurellales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DTH3_k127_8619146_2	452637.Oter_0025	8.232e-45	181.0	COG1538@1|root,COG1538@2|Bacteria,46VZS@74201|Verrucomicrobia,3K7CV@414999|Opitutae	414999|Opitutae	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH3_k127_8619146_0	204669.Acid345_4092	1.861e-82	286.0	COG0009@1|root,COG0009@2|Bacteria,3Y3VW@57723|Acidobacteria,2JHTT@204432|Acidobacteriia	204432|Acidobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
DTH3_k127_8619146_1	497964.CfE428DRAFT_2629	2.565e-75	266.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
DTH3_k127_8619146_5	1869.MB27_39975	3.578e-07	62.0	2EGCD@1|root,33A46@2|Bacteria,2HUKV@201174|Actinobacteria,4DFF1@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
DTH3_k127_8619146_6	1303518.CCALI_02493	1.962e-06	59.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_8631147_1	1449063.JMLS01000007_gene3393	2.039e-46	173.0	COG1621@1|root,COG1621@2|Bacteria,1V0FY@1239|Firmicutes,4IPFZ@91061|Bacilli,26UC0@186822|Paenibacillaceae	91061|Bacilli	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8631147_0	315750.BPUM_1558	3.427e-49	196.0	COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,1ZE8U@1386|Bacillus	91061|Bacilli	G	Cellulose binding domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Glyco_hydro_9
DTH3_k127_8633063_8	1304284.L21TH_2502	1.022e-09	61.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,36E3A@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH3_k127_8633063_3	1123277.KB893217_gene4667	4.866e-19	91.0	COG2405@1|root,COG2405@2|Bacteria,4NVKA@976|Bacteroidetes,47X58@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
DTH3_k127_8633063_9	489825.LYNGBM3L_48350	1.164e-06	53.0	COG2405@1|root,COG2405@2|Bacteria,1G725@1117|Cyanobacteria,1HATZ@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
DTH3_k127_8633063_4	1209989.TepiRe1_1613	5.922e-15	77.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DTH3_k127_8633063_7	1210884.HG799464_gene10957	2.497e-11	75.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_8633063_10	1210884.HG799464_gene10719	0.000488	51.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132,HEAT_2
DTH3_k127_8633063_0	497964.CfE428DRAFT_3303	4.869e-237	744.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DTH3_k127_8633063_1	338963.Pcar_1946	2.184e-66	234.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DTH3_k127_8633063_6	518766.Rmar_0899	1.588e-12	73.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DTH3_k127_8645198_4	870187.Thini_1532	3.484e-20	95.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Cadherin_3,Calx-beta,DUF4347,He_PIG,Invasin_D3,Laminin_G_3,Lectin_C,PA14,Pentaxin,Peptidase_S74
DTH3_k127_8645198_6	316274.Haur_2191	5.917e-10	66.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K11904,ko:K12132	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02044	3.A.23.1	-	-	DUF1565,DUF3494,Pkinase,SLH,TadE
DTH3_k127_8645198_0	481448.Minf_1814	3.136e-261	823.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,37GG7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DTH3_k127_8645198_3	997346.HMPREF9374_0351	1.132e-40	163.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli,27BZ5@186824|Thermoactinomycetaceae	91061|Bacilli	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
DTH3_k127_8645198_1	472759.Nhal_3844	3.432e-64	226.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1WWQ9@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
DTH3_k127_8645198_2	1125863.JAFN01000001_gene972	2.923e-41	162.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
DTH3_k127_8645198_5	1340493.JNIF01000003_gene4360	5.839e-17	87.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM60,Cu-binding_MopE,DUF4214,Peptidase_M10,Peptidase_S8
DTH3_k127_864961_2	1396418.BATQ01000088_gene1036	9.498e-99	333.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
DTH3_k127_864961_3	1121430.JMLG01000019_gene1656	1.103e-84	297.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
DTH3_k127_864961_4	497964.CfE428DRAFT_0998	7.179e-52	192.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DTH3_k127_864961_5	497964.CfE428DRAFT_1520	5.63e-43	160.0	COG0251@1|root,COG0251@2|Bacteria,46T40@74201|Verrucomicrobia	74201|Verrucomicrobia	J	endoribonuclease L-PSP	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Ribonuc_L-PSP
DTH3_k127_864961_1	1121875.KB907547_gene3471	6.071e-117	393.0	2C20F@1|root,32R9J@2|Bacteria,4P0SP@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
DTH3_k127_864961_0	278957.ABEA03000215_gene4275	1.223e-147	480.0	COG0165@1|root,COG0165@2|Bacteria,46UYU@74201|Verrucomicrobia,3K76F@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
DTH3_k127_8650596_1	1240350.AMZE01000024_gene1610	2.728e-93	321.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
DTH3_k127_8650596_2	1123256.KB907940_gene188	1.864e-22	104.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
DTH3_k127_8650596_0	497964.CfE428DRAFT_4177	4.04e-161	515.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DTH3_k127_8653984_2	240016.ABIZ01000001_gene1588	1.11e-86	300.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_8653984_1	1185876.BN8_06038	7.513e-105	351.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,47JP9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DTH3_k127_8653984_0	886293.Sinac_0736	5.512e-154	512.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2IYAH@203682|Planctomycetes	203682|Planctomycetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
DTH3_k127_8662690_3	909663.KI867151_gene2986	1.434e-17	87.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,2MR6R@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DTH3_k127_8662690_0	1379698.RBG1_1C00001G1246	6.618e-65	235.0	COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria	2|Bacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
DTH3_k127_8662690_2	497964.CfE428DRAFT_4665	2.8e-34	140.0	COG0781@1|root,COG0781@2|Bacteria,46T7V@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DTH3_k127_8662690_1	1396141.BATP01000027_gene1089	1.967e-37	164.0	COG5373@1|root,COG5373@2|Bacteria,46S9T@74201|Verrucomicrobia,2IUWT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
DTH3_k127_8663668_0	497964.CfE428DRAFT_0257	6.355e-222	720.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
DTH3_k127_8663668_1	497964.CfE428DRAFT_0262	1.285e-41	161.0	COG0688@1|root,COG0688@2|Bacteria,46VRI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DTH3_k127_8663668_2	478741.JAFS01000002_gene560	1.036e-24	109.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,37G2T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	CDP-alcohol phosphatidyltransferase	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DTH3_k127_8666801_1	1121920.AUAU01000024_gene2381	1.943e-61	235.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DTH3_k127_8666801_0	243231.GSU2888	1.127e-162	529.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
DTH3_k127_8666801_2	1121920.AUAU01000024_gene2386	2.266e-40	151.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DTH3_k127_8668078_0	1191523.MROS_1318	3.455e-132	440.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DTH3_k127_8668078_1	497964.CfE428DRAFT_6050	7.313e-104	343.0	COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
DTH3_k127_8672571_0	583355.Caka_3039	5.288e-160	525.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8672571_1	1291050.JAGE01000001_gene867	4.244e-62	226.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DTH3_k127_8683322_0	1232410.KI421415_gene2957	4.468e-82	283.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43S1Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	HK	HTH domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
DTH3_k127_8683322_1	595536.ADVE02000001_gene2653	5.6e-81	279.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2TS7C@28211|Alphaproteobacteria,36X2F@31993|Methylocystaceae	28211|Alphaproteobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
DTH3_k127_8683322_2	497964.CfE428DRAFT_3476	1.206e-56	215.0	COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
DTH3_k127_8683322_3	215803.DB30_7465	1.149e-40	156.0	2E69S@1|root,330XP@2|Bacteria,1N7XM@1224|Proteobacteria	1224|Proteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
DTH3_k127_8710643_0	452637.Oter_0618	9.685e-219	689.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DTH3_k127_8710643_1	257313.BP2758	1.13e-19	99.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,3T4GB@506|Alcaligenaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
DTH3_k127_8711758_2	929556.Solca_2367	2.521e-42	183.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,HemolysinCabind,IgGFc_binding
DTH3_k127_8711758_6	929703.KE386491_gene2364	2.149e-06	64.0	COG2373@1|root,COG3209@1|root,COG3291@1|root,COG4386@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,COG4932@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
DTH3_k127_8711758_1	864702.OsccyDRAFT_2745	5.741e-109	404.0	COG2931@1|root,COG2931@2|Bacteria,1GHDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
DTH3_k127_8711758_4	340177.Cag_0614	1.854e-17	101.0	COG1357@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	rhgB	-	4.2.2.23	ko:K07004,ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
DTH3_k127_8711758_8	1116375.VEJY3_21071	0.0003282	49.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,1XVDW@135623|Vibrionales	135623|Vibrionales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
DTH3_k127_8711758_5	420324.KI911932_gene324	4.062e-16	82.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
DTH3_k127_8711758_3	94624.Bpet1408	2.886e-37	147.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
DTH3_k127_8711758_0	94624.Bpet1409	5.444e-240	767.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH3_k127_8711758_7	883078.HMPREF9695_00512	5.335e-06	57.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2TQPC@28211|Alphaproteobacteria,3JZ69@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
DTH3_k127_8719891_1	67267.JNXT01000002_gene6028	3.376e-10	70.0	COG3511@1|root,COG3511@2|Bacteria,2GQGM@201174|Actinobacteria	201174|Actinobacteria	M	hydrolase, family 65, central catalytic	-	-	3.1.3.64	ko:K21302	ko00562,ko01100,ko05152,map00562,map01100,map05152	-	-	-	ko00000,ko00001,ko01000	-	-	-	Phosphoesterase
DTH3_k127_8719891_0	661478.OP10G_0968	7.8e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_8756143_2	1492737.FEM08_16420	2.686e-172	567.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_8756143_0	452637.Oter_1883	3.575e-311	972.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_8756143_1	452637.Oter_1829	6.38e-174	573.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_8756143_3	452637.Oter_1829	5.862e-120	406.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_8765677_0	661478.OP10G_3858	2.864e-119	391.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yrbE	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DTH3_k127_8765677_1	497964.CfE428DRAFT_3531	5.097e-114	378.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
DTH3_k127_8765677_2	497964.CfE428DRAFT_0769	1.029e-107	368.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_8765677_3	1499967.BAYZ01000159_gene538	1.594e-09	59.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_8767432_1	497964.CfE428DRAFT_2490	2.722e-133	441.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
DTH3_k127_8767432_0	1123242.JH636434_gene3280	4.109e-158	511.0	COG0823@1|root,COG0823@2|Bacteria,2IYQ1@203682|Planctomycetes	203682|Planctomycetes	U	Protein of unknown function (DUF3748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
DTH3_k127_8767432_3	269799.Gmet_2367	8.577e-80	288.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DTH3_k127_8767432_2	1211777.BN77_p2190020	1.181e-117	389.0	COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,2TTTJ@28211|Alphaproteobacteria,4BCIX@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	NAD(P)H-binding	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DTH3_k127_8769619_1	497964.CfE428DRAFT_1084	6.926e-108	353.0	COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
DTH3_k127_8769619_0	1121957.ATVL01000014_gene1459	7.602e-148	509.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8793045_1	382464.ABSI01000010_gene3213	1.983e-153	497.0	COG0673@1|root,COG0673@2|Bacteria,46UYM@74201|Verrucomicrobia,2IVG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_8793045_0	497964.CfE428DRAFT_3010	0.0	1395.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH3_k127_8793045_2	497964.CfE428DRAFT_5350	1.632e-94	323.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
DTH3_k127_8794793_4	1340493.JNIF01000003_gene2222	3.544e-17	83.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DTH3_k127_8794793_0	472759.Nhal_2032	4.108e-160	519.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales	135613|Chromatiales	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
DTH3_k127_8794793_2	504472.Slin_1223	9.518e-108	358.0	COG2755@1|root,COG2755@2|Bacteria,4NIBN@976|Bacteroidetes,47NY7@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
DTH3_k127_8794793_1	1254432.SCE1572_30435	8.154e-123	401.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DTH3_k127_8794793_3	794903.OPIT5_30270	8.472e-24	108.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	mauE	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
DTH3_k127_879962_2	515635.Dtur_1279	1.122e-29	124.0	COG0536@1|root,COG0536@2|Bacteria	2|Bacteria	C	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
DTH3_k127_879962_1	497964.CfE428DRAFT_6605	3.799e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DTH3_k127_879962_3	1280950.HJO_06350	1.38e-27	115.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,43XSM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
DTH3_k127_879962_4	330214.NIDE3682	1.799e-24	108.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
DTH3_k127_879962_0	1070319.CAGGBEG34_190038	2.741e-110	375.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
DTH3_k127_879962_5	768066.HELO_3427	6.777e-05	50.0	COG3339@1|root,COG3339@2|Bacteria,1N9BI@1224|Proteobacteria,1SC8Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
DTH3_k127_8799779_0	794903.OPIT5_27320	7.195e-74	256.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DTH3_k127_8799779_2	1123276.KB893245_gene1757	8.07e-10	66.0	29Q3N@1|root,30B2B@2|Bacteria,4NPCV@976|Bacteroidetes,47Q0V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8799779_1	443143.GM18_0916	1.145e-15	84.0	COG2133@1|root,COG4447@1|root,COG4733@1|root,COG2133@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DTH3_k127_8806512_1	1267535.KB906767_gene4118	1.524e-39	153.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
DTH3_k127_8806512_3	1207076.ALAT01000184_gene2651	0.0001368	47.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1Z0P7@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
DTH3_k127_8806512_0	497964.CfE428DRAFT_3399	8.818e-78	276.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH3_k127_8806512_2	525897.Dbac_1691	1.259e-11	77.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM O-Antigen	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_14,TPR_16,TPR_8,Wzy_C
DTH3_k127_8810447_0	526218.Sterm_1103	2.386e-72	255.0	COG1940@1|root,COG1940@2|Bacteria,378B8@32066|Fusobacteria	2|Bacteria	GK	Psort location Cytoplasmic, score 9.97	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH3_k127_8810447_1	1459636.NTE_00049	8.812e-28	119.0	COG2062@1|root,arCOG01992@2157|Archaea	2157|Archaea	T	TIGRFAM phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
DTH3_k127_8810447_2	857087.Metme_0945	1.096e-16	90.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	sixA-2	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,His_Phos_1
DTH3_k127_8811113_1	661478.OP10G_4802	2.43e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_8811113_0	1380763.BG53_03870	3.993e-40	162.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
DTH3_k127_881765_1	595460.RRSWK_04460	4.833e-47	181.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
DTH3_k127_881765_0	1123242.JH636436_gene23	4.67e-69	254.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DTH3_k127_883324_6	1123508.JH636445_gene6824	1.093e-05	54.0	COG4805@1|root,COG4805@2|Bacteria,2IXQZ@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DTH3_k127_883324_0	1396418.BATQ01000175_gene2745	3.529e-81	278.0	COG1387@1|root,COG1387@2|Bacteria,46SMB@74201|Verrucomicrobia,2IU6X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
DTH3_k127_883324_2	1125863.JAFN01000001_gene1790	2.295e-42	162.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DTH3_k127_883324_1	452637.Oter_2449	1.807e-66	233.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K7Y9@414999|Opitutae	414999|Opitutae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DTH3_k127_883324_8	1453505.JASY01000013_gene4343	0.0004876	49.0	2CIT3@1|root,32Y0C@2|Bacteria,4NUWR@976|Bacteroidetes,1I533@117743|Flavobacteriia,2NWGN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
DTH3_k127_883324_3	794903.OPIT5_19905	4.469e-26	115.0	COG0250@1|root,COG0250@2|Bacteria,46XU3@74201|Verrucomicrobia,3K844@414999|Opitutae	414999|Opitutae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
DTH3_k127_883324_4	243231.GSU2083	2.226e-15	76.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria,43S7Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH3_k127_8837325_3	1403819.BATR01000094_gene2950	9.226e-07	53.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,2IUW5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
DTH3_k127_8837325_2	886293.Sinac_7310	1.455e-116	383.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DTH3_k127_8837325_0	234267.Acid_3246	1.477e-182	584.0	COG0673@1|root,COG0673@2|Bacteria,3Y76D@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DTH3_k127_8837325_1	497964.CfE428DRAFT_4366	6.276e-126	417.0	COG1520@1|root,COG1520@2|Bacteria,46TRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DTH3_k127_8837325_4	1173023.KE650771_gene2595	1.893e-05	50.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,1JHUA@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
DTH3_k127_8840026_2	497964.CfE428DRAFT_1992	4.091e-88	298.0	COG3938@1|root,COG3938@2|Bacteria,46U8C@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Proline racemase	-	-	-	-	-	-	-	-	-	-	-	-	Pro_racemase
DTH3_k127_8840026_3	886293.Sinac_7025	2.241e-87	293.0	COG1225@1|root,COG1225@2|Bacteria,2IYHT@203682|Planctomycetes	203682|Planctomycetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DTH3_k127_8840026_1	497964.CfE428DRAFT_1931	1.819e-94	319.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DTH3_k127_8840026_0	1254432.SCE1572_30430	5.077e-167	537.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X250@28221|Deltaproteobacteria,2YXZE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_8840653_1	382464.ABSI01000013_gene1636	3.511e-83	284.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DTH3_k127_8840653_0	452637.Oter_4549	8.866e-89	299.0	28JIN@1|root,30U02@2|Bacteria,46YTT@74201|Verrucomicrobia,3K7XH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8853490_1	1396418.BATQ01000106_gene5306	1.397e-30	133.0	2DTXG@1|root,33N3G@2|Bacteria,46WXU@74201|Verrucomicrobia,2IVTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DTH3_k127_8853490_0	1121405.dsmv_1085	8.944e-125	421.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
DTH3_k127_8860065_0	382464.ABSI01000002_gene4277	1.872e-94	316.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,2ITV8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DTH3_k127_8860065_2	382464.ABSI01000013_gene1727	5.877e-57	207.0	COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia	74201|Verrucomicrobia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM
DTH3_k127_8860065_1	1396418.BATQ01000017_gene4190	9.662e-63	232.0	COG4714@1|root,COG4714@2|Bacteria,46WYQ@74201|Verrucomicrobia,2IUN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
DTH3_k127_8860065_3	1192034.CAP_8221	2.573e-13	75.0	2C9T2@1|root,347D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8885418_10	1167006.UWK_00742	1.161e-26	117.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
DTH3_k127_8885418_12	880073.Calab_2477	4.448e-07	58.0	2E5Q4@1|root,330ER@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8885418_9	452637.Oter_2332	1.399e-35	143.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,3K82A@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
DTH3_k127_8885418_8	794903.OPIT5_19655	5.253e-41	162.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DTH3_k127_8885418_11	478741.JAFS01000001_gene1845	8.799e-12	69.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,37GXZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DTH3_k127_8885418_6	111781.Lepto7376_3170	7.052e-50	184.0	COG0193@1|root,COG0193@2|Bacteria,1G0D0@1117|Cyanobacteria,1H70D@1150|Oscillatoriales	1117|Cyanobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DTH3_k127_8885418_5	497964.CfE428DRAFT_1544	1.657e-55	204.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DTH3_k127_8885418_2	1156937.MFUM_870060	6.498e-130	421.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,37GGN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
DTH3_k127_8885418_3	497964.CfE428DRAFT_4701	4.041e-116	388.0	COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DTH3_k127_8885418_0	452637.Oter_2432	3.409e-260	811.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,3K77C@414999|Opitutae	414999|Opitutae	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
DTH3_k127_8885418_4	497964.CfE428DRAFT_4585	1.996e-112	365.0	COG0175@1|root,COG0175@2|Bacteria,46SNE@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH3_k127_8885418_1	452637.Oter_2430	6.826e-169	533.0	COG0175@1|root,COG0175@2|Bacteria,46TUQ@74201|Verrucomicrobia,3K7NR@414999|Opitutae	74201|Verrucomicrobia	H	PFAM phosphoadenosine phosphosulfate reductase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
DTH3_k127_8885418_7	497964.CfE428DRAFT_4587	1.251e-41	155.0	COG2895@1|root,COG2895@2|Bacteria,46SN4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
DTH3_k127_8908600_4	497964.CfE428DRAFT_0873	3.195e-50	180.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
DTH3_k127_8908600_7	1156937.MFUM_260026	7.624e-27	118.0	COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,37H9P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
DTH3_k127_8908600_0	497964.CfE428DRAFT_0194	0.0	1654.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
DTH3_k127_8908600_3	497964.CfE428DRAFT_0193	7.035e-111	364.0	COG1210@1|root,COG1210@2|Bacteria,46S5P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DTH3_k127_8908600_2	497964.CfE428DRAFT_2266	1.815e-199	630.0	COG0477@1|root,COG2814@2|Bacteria,46U08@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
DTH3_k127_8908600_5	1403819.BATR01000049_gene1427	4.867e-45	170.0	COG0424@1|root,COG0424@2|Bacteria,46VR6@74201|Verrucomicrobia,2IUHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Maf-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Maf
DTH3_k127_8908600_1	234267.Acid_6385	2.961e-202	644.0	COG0405@1|root,COG0405@2|Bacteria,3Y2I7@57723|Acidobacteria	57723|Acidobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
DTH3_k127_8908600_6	596151.DesfrDRAFT_3540	3.41e-35	134.0	COG1449@1|root,COG1449@2|Bacteria,1PUYM@1224|Proteobacteria,42MQP@68525|delta/epsilon subdivisions,2WKP2@28221|Deltaproteobacteria,2M8R3@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
DTH3_k127_8913702_2	1403819.BATR01000069_gene2016	5.086e-33	131.0	COG2197@1|root,COG2197@2|Bacteria,46U17@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_8913702_0	497964.CfE428DRAFT_5498	3.213e-144	471.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	cefD	-	5.1.1.17	ko:K04127,ko:K11325,ko:K21174	ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130	M00673,M00825	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
DTH3_k127_8913702_1	395494.Galf_2064	8.793e-77	278.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
DTH3_k127_8924514_3	794903.OPIT5_11525	4.338e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,46Z9D@74201|Verrucomicrobia,3K9IE@414999|Opitutae	2|Bacteria	U	Protein of unknown function (DUF1559)	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_8924514_2	452637.Oter_3570	2.949e-25	117.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8924514_0	1396141.BATP01000032_gene4324	2.188e-157	521.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DTH3_k127_8924514_1	497964.CfE428DRAFT_5735	8.181e-45	182.0	COG4796@1|root,COG4796@2|Bacteria,46STU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
DTH3_k127_8926484_4	266809.PM03_10895	1.471e-11	65.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DTH3_k127_8926484_0	111781.Lepto7376_0105	1.908e-72	262.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
DTH3_k127_8926484_3	794903.OPIT5_29985	1.128e-12	71.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH3_k127_8926484_1	794903.OPIT5_29985	8.634e-72	255.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DTH3_k127_8926484_2	338969.Rfer_1071	6.218e-14	80.0	COG1028@1|root,COG1028@2|Bacteria,1RBAD@1224|Proteobacteria,2VI9U@28216|Betaproteobacteria,4AA6I@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase Sdr	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8926968_2	391612.CY0110_08276	5.489e-18	98.0	COG2304@1|root,COG3210@1|root,COG2304@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,DUF4214,HemolysinCabind,SdrD_B,VWA,VWA_2
DTH3_k127_8926968_0	661478.OP10G_2626	6.1e-159	523.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
DTH3_k127_8926968_1	1122927.KB895432_gene143	1.461e-43	169.0	COG3669@1|root,COG4099@1|root,COG5492@1|root,COG3669@2|Bacteria,COG4099@2|Bacteria,COG5492@2|Bacteria,1TQH2@1239|Firmicutes,4HTW2@91061|Bacilli,275UU@186822|Paenibacillaceae	91061|Bacilli	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
DTH3_k127_893747_0	497964.CfE428DRAFT_1043	6.737e-128	418.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DTH3_k127_893747_4	1396141.BATP01000023_gene577	1.637e-27	122.0	COG0132@1|root,COG0132@2|Bacteria,46VJB@74201|Verrucomicrobia,2IUDQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
DTH3_k127_893747_2	670487.Ocepr_1062	1.744e-35	140.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,1WN2N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
DTH3_k127_893747_3	1210884.HG799479_gene15512	1.255e-29	126.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
DTH3_k127_893747_6	1123508.JH636456_gene119	8.643e-12	72.0	COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
DTH3_k127_893747_1	671143.DAMO_0981	2.975e-82	278.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
DTH3_k127_8961331_0	1403819.BATR01000114_gene3955	1.233e-290	933.0	COG1674@1|root,COG1674@2|Bacteria,46V0I@74201|Verrucomicrobia,2IVES@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	FtsK/SpoIIIE family	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
DTH3_k127_8961331_1	886293.Sinac_5304	7.747e-40	160.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
DTH3_k127_8964441_2	452637.Oter_2787	5.587e-50	190.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DTH3_k127_8964441_3	661478.OP10G_0968	9.294e-15	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
DTH3_k127_8964441_1	272123.Anacy_2354	1.629e-142	466.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,1HIFU@1161|Nostocales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DTH3_k127_8964441_4	555079.Toce_2158	1.698e-05	54.0	2E2B7@1|root,32XGJ@2|Bacteria,1UPQ4@1239|Firmicutes,25HKV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8964441_0	886293.Sinac_7036	1.271e-166	530.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8976236_3	382464.ABSI01000010_gene3644	2.614e-83	285.0	COG0407@1|root,COG0407@2|Bacteria,46X9N@74201|Verrucomicrobia,2IV4H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH3_k127_8976236_4	452637.Oter_0906	1.25e-46	179.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
DTH3_k127_8976236_2	452637.Oter_2583	5.136e-88	299.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH3_k127_8976236_5	1191523.MROS_2048	1.091e-21	110.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
DTH3_k127_8976236_6	1396141.BATP01000019_gene1718	2.351e-12	78.0	COG3225@1|root,COG3225@2|Bacteria,46UZA@74201|Verrucomicrobia,2IUBV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
DTH3_k127_8976236_0	756272.Plabr_0818	2.667e-211	668.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
DTH3_k127_8977983_0	583355.Caka_1289	8.811e-179	571.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,3K7HP@414999|Opitutae	414999|Opitutae	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DTH3_k127_8977983_3	191610.CATYP_00200	0.0002279	49.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,22M4R@1653|Corynebacteriaceae	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
DTH3_k127_8977983_2	794903.OPIT5_22505	8.822e-08	63.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia,3K89I@414999|Opitutae	414999|Opitutae	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
DTH3_k127_8977983_1	497964.CfE428DRAFT_6114	8.297e-109	376.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
DTH3_k127_8981293_2	1235457.C404_29380	4.474e-18	85.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,1K10X@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
DTH3_k127_8981293_3	1496688.ER33_10290	0.0001211	45.0	COG1525@1|root,COG1525@2|Bacteria,1GEHA@1117|Cyanobacteria,22TRR@167375|Cyanobium	1117|Cyanobacteria	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
DTH3_k127_8981293_1	1198452.Jab_2c16640	4.623e-46	176.0	2BIJA@1|root,32CS2@2|Bacteria,1RHJT@1224|Proteobacteria,2VT9T@28216|Betaproteobacteria,477I4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,VPEP
DTH3_k127_8981293_0	1209072.ALBT01000033_gene1684	2.064e-99	331.0	29VUZ@1|root,30HCS@2|Bacteria,1NJ74@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_8985883_3	497964.CfE428DRAFT_1197	1.956e-10	64.0	COG0859@1|root,COG0859@2|Bacteria,46T6R@74201|Verrucomicrobia	74201|Verrucomicrobia	M	glycosyl transferase family 9	-	-	-	ko:K02841,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DTH3_k127_8985883_0	497964.CfE428DRAFT_1198	2.573e-101	334.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
DTH3_k127_8985883_2	240016.ABIZ01000001_gene2409	7.545e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,2IUZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
DTH3_k127_8985883_1	575540.Isop_2740	1.767e-75	271.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
DTH3_k127_8989907_0	1122179.KB890442_gene1152	3.428e-48	198.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_8989907_1	1396141.BATP01000043_gene1929	1.468e-42	180.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
DTH3_k127_8991578_2	91464.S7335_2833	5.301e-35	137.0	COG1194@1|root,COG1194@2|Bacteria,1G7MC@1117|Cyanobacteria,1GYRR@1129|Synechococcus	1117|Cyanobacteria	L	A G-specific DNA glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DTH3_k127_8991578_1	497964.CfE428DRAFT_4766	6.656e-88	303.0	COG1039@1|root,COG1039@2|Bacteria,46UTB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DTH3_k127_8991578_0	452637.Oter_0239	5.659e-172	546.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DTH3_k127_8994329_1	1298860.AUEM01000004_gene3282	2.86e-18	98.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Laminin_G_3
DTH3_k127_8994329_0	497964.CfE428DRAFT_2594	4.429e-61	220.0	COG2138@1|root,COG2138@2|Bacteria,46SPE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
DTH3_k127_8999003_3	497964.CfE428DRAFT_3924	1.476e-63	223.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DTH3_k127_8999003_5	742742.HMPREF9452_01467	1.385e-20	99.0	COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DTH3_k127_8999003_1	452637.Oter_3498	2.619e-135	439.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DTH3_k127_8999003_4	314230.DSM3645_05160	3.283e-55	199.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
DTH3_k127_8999003_6	589865.DaAHT2_0949	1.192e-15	80.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
DTH3_k127_8999003_2	382464.ABSI01000013_gene1799	1.27e-104	356.0	COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,2IU82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Divalent cation transporter	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
DTH3_k127_8999003_8	278957.ABEA03000005_gene4419	1.27e-09	64.0	COG5393@1|root,COG5393@2|Bacteria,46XW8@74201|Verrucomicrobia,3K8G8@414999|Opitutae	414999|Opitutae	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
DTH3_k127_8999003_7	452637.Oter_1161	1.166e-14	83.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
DTH3_k127_8999003_0	886293.Sinac_0926	1.363e-212	671.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
DTH3_k127_9001626_2	337075.U4L094	7.96e-07	61.0	2993U@1|root,2RG5A@2759|Eukaryota,38E92@33154|Opisthokonta,3NXE3@4751|Fungi,3QR0B@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9001626_0	880073.Calab_1549	8.997e-221	724.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
DTH3_k127_9001626_1	257314.LJ_0733	5.263e-20	95.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F54Z@33958|Lactobacillaceae	91061|Bacilli	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	celD	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
DTH3_k127_9014435_3	1121920.AUAU01000009_gene1881	1.132e-13	83.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
DTH3_k127_9014435_2	481448.Minf_1759	1.273e-32	136.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,37GRJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DTH3_k127_9014435_1	497964.CfE428DRAFT_0115	2.924e-94	314.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
DTH3_k127_9014435_0	330214.NIDE0577	1.567e-311	978.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
DTH3_k127_9014435_4	115713.CPn_0557	2.578e-05	47.0	COG1361@1|root,COG1361@2|Bacteria,2JFMZ@204428|Chlamydiae	204428|Chlamydiae	M	In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin. It has been described in publications as the Sarkosyl- insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan	omcB	-	-	-	-	-	-	-	-	-	-	-	Chlam_OMP6,DUF11
DTH3_k127_9016374_0	926549.KI421517_gene437	7.918e-82	279.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,SAM_MT
DTH3_k127_9016374_3	1485545.JQLW01000005_gene1063	1.075e-41	162.0	COG2227@1|root,COG2227@2|Bacteria,1QY24@1224|Proteobacteria	1224|Proteobacteria	H	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
DTH3_k127_9016374_2	690850.Desaf_0021	1.634e-61	227.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2MG43@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DTH3_k127_9016374_1	690850.Desaf_0024	1.066e-80	274.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MHBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_9019207_7	861299.J421_1753	0.0002263	45.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
DTH3_k127_9019207_2	1288963.ADIS_1386	4.322e-103	369.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9019207_6	580331.Thit_1725	4.015e-34	153.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,24DCW@186801|Clostridia,42FHF@68295|Thermoanaerobacterales	186801|Clostridia	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
DTH3_k127_9019207_0	452637.Oter_2942	2.452e-203	651.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
DTH3_k127_9019207_4	234267.Acid_6078	1.007e-35	153.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PD40,SdrD_B
DTH3_k127_9019207_1	335543.Sfum_1622	1.083e-128	438.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C554
DTH3_k127_9019207_3	234267.Acid_6081	1.807e-71	256.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,HATPase_c,PKD_3,Reg_prop
DTH3_k127_9019207_5	335543.Sfum_1620	8.402e-35	143.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
DTH3_k127_9034200_1	378806.STAUR_7504	8.785e-161	544.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QUYA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
DTH3_k127_9034200_2	497964.CfE428DRAFT_5731	7.579e-64	225.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DTH3_k127_9034200_0	497964.CfE428DRAFT_6370	2.198e-163	529.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
DTH3_k127_9035867_0	497964.CfE428DRAFT_5670	3.296e-143	465.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
DTH3_k127_9035867_1	886293.Sinac_7506	1.274e-09	69.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DTH3_k127_9044337_0	471854.Dfer_1900	7.467e-28	128.0	COG4409@1|root,COG4409@2|Bacteria,4P66K@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_9044337_1	1048834.TC41_0922	1.374e-07	63.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli	91061|Bacilli	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
DTH3_k127_9060510_0	1403819.BATR01000007_gene203	1.079e-261	836.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,DUF1080,GSDH,HEAT_2,Laminin_G_3,Lipase_GDSL_2,ThuA
DTH3_k127_9062614_1	404589.Anae109_3548	1.275e-32	148.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
DTH3_k127_9062614_2	635013.TherJR_1425	1.811e-07	65.0	COG3005@1|root,COG4733@1|root,COG3005@2|Bacteria,COG4733@2|Bacteria,1UT1Y@1239|Firmicutes,250WR@186801|Clostridia,265BU@186807|Peptococcaceae	186801|Clostridia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
DTH3_k127_9062614_0	497964.CfE428DRAFT_5270	1.59e-45	167.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
DTH3_k127_9071310_0	1227360.C176_13277	7.929e-76	283.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,26EP7@186818|Planococcaceae	91061|Bacilli	S	Penicillin acylase	acyII	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DTH3_k127_9071926_0	886293.Sinac_4798	2.889e-119	398.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DTH3_k127_9071926_2	530564.Psta_4732	1.498e-83	286.0	COG1136@1|root,COG1136@2|Bacteria,2IY81@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DTH3_k127_9071926_3	1232437.KL662020_gene700	7.258e-80	290.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DTH3_k127_9071926_5	1167006.UWK_02169	3.628e-52	206.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DTH3_k127_9071926_1	1396418.BATQ01000113_gene4631	2.188e-118	392.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
DTH3_k127_9071926_4	497964.CfE428DRAFT_3322	9.263e-75	261.0	COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
DTH3_k127_9077668_0	1123508.JH636439_gene1370	6.628e-142	460.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
DTH3_k127_9077668_1	1396141.BATP01000022_gene421	6.315e-41	163.0	2BVGP@1|root,32QVG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9124012_0	1123508.JH636445_gene6496	2.684e-142	471.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
DTH3_k127_9126927_8	768706.Desor_1391	6.257e-09	68.0	COG2247@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3386@2|Bacteria,1VMQN@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
DTH3_k127_9126927_4	1192034.CAP_0893	2.258e-57	226.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
DTH3_k127_9126927_3	1173028.ANKO01000062_gene2255	6.338e-61	237.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1G02E@1117|Cyanobacteria,1H9TQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
DTH3_k127_9126927_1	1123242.JH636434_gene3333	1.296e-109	366.0	COG4692@1|root,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_9126927_6	278957.ABEA03000041_gene2103	7.594e-30	121.0	COG4974@1|root,COG4974@2|Bacteria,46U04@74201|Verrucomicrobia,3K7J0@414999|Opitutae	414999|Opitutae	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH3_k127_9126927_5	497964.CfE428DRAFT_4930	1.191e-42	164.0	COG4974@1|root,COG4974@2|Bacteria,46SQ4@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DTH3_k127_9126927_7	1131269.AQVV01000100_gene2556	2.734e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
DTH3_k127_9126927_0	243233.MCA2161	3.904e-167	550.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9126927_9	435590.BVU_3393	6.594e-07	61.0	COG0550@1|root,COG0550@2|Bacteria,4P23D@976|Bacteroidetes,2FM96@200643|Bacteroidia,4APZ9@815|Bacteroidaceae	976|Bacteroidetes	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_Crpt
DTH3_k127_9126927_2	640081.Dsui_0821	1.48e-93	319.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
DTH3_k127_9163643_4	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
DTH3_k127_9163643_2	1192868.CAIU01000040_gene4440	1.488e-08	56.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DTH3_k127_9163643_0	1121101.HMPREF1532_01876	4.073e-123	418.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FVA6@200643|Bacteroidia,4AT0B@815|Bacteroidaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
DTH3_k127_9163643_1	880073.Calab_0674	7.115e-12	79.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
DTH3_k127_9163643_3	497964.CfE428DRAFT_4678	5.101e-08	66.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
DTH3_k127_9164893_3	402880.MmarC5_0718	3.341e-15	83.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23QEP@183939|Methanococci	183939|Methanococci	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DTH3_k127_9164893_1	596151.DesfrDRAFT_0880	5.009e-38	151.0	COG4273@1|root,COG4273@2|Bacteria,1MZED@1224|Proteobacteria,42UH2@68525|delta/epsilon subdivisions,2WQNQ@28221|Deltaproteobacteria,2MBB6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DGC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DGC
DTH3_k127_9164893_2	398767.Glov_1181	3.323e-15	85.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxB	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
DTH3_k127_9164893_0	909663.KI867150_gene1425	2.411e-78	265.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DTH3_k127_9167949_1	497964.CfE428DRAFT_3698	2.054e-37	143.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
DTH3_k127_9167949_0	118173.KB235914_gene3829	4.44e-138	465.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9167949_2	1303518.CCALI_00133	1.161e-31	143.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	galA	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_4_9,CBM_6,DUF1565
DTH3_k127_9169488_1	649349.Lbys_0018	1.58e-27	113.0	COG1082@1|root,COG1082@2|Bacteria,4NHMP@976|Bacteroidetes,47NUC@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
DTH3_k127_9169488_0	485913.Krac_4320	7.169e-234	734.0	COG3962@1|root,COG3962@2|Bacteria,2G68S@200795|Chloroflexi	200795|Chloroflexi	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DTH3_k127_9176686_2	583355.Caka_1232	2.312e-22	109.0	COG5523@1|root,COG5523@2|Bacteria,46ZK6@74201|Verrucomicrobia,3KA3R@414999|Opitutae	2|Bacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
DTH3_k127_9176686_4	771875.Ferpe_1246	9.727e-10	62.0	COG0230@1|root,COG0230@2|Bacteria,2GDMP@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DTH3_k127_9176686_3	756499.Desde_4254	1.815e-11	70.0	COG0594@1|root,COG0594@2|Bacteria,1TV50@1239|Firmicutes,259HJ@186801|Clostridia,2633N@186807|Peptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DTH3_k127_9176686_1	1244869.H261_16660	3.446e-23	104.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2JTTP@204441|Rhodospirillales	204441|Rhodospirillales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DTH3_k127_9176686_0	478741.JAFS01000001_gene1099	1.745e-54	210.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,37FV2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
DTH3_k127_9212778_1	1123242.JH636435_gene2066	2.794e-65	237.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DTH3_k127_9212778_0	497964.CfE428DRAFT_5897	1.421e-225	724.0	COG1073@1|root,COG1073@2|Bacteria,46TMQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9213388_0	497964.CfE428DRAFT_0111	3.177e-43	177.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9217498_2	1403819.BATR01000135_gene4812	5.242e-115	380.0	COG0329@1|root,COG0329@2|Bacteria,46UU4@74201|Verrucomicrobia	74201|Verrucomicrobia	EM	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
DTH3_k127_9217498_1	1123242.JH636434_gene4153	1.529e-152	492.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DTH3_k127_9217498_0	1123269.NX02_17320	3.726e-193	611.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2K15R@204457|Sphingomonadales	204457|Sphingomonadales	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
DTH3_k127_9217498_3	411902.CLOBOL_03557	1.066e-25	110.0	COG2721@1|root,COG2721@2|Bacteria,1TUD7@1239|Firmicutes,24R3M@186801|Clostridia,221BF@1506553|Lachnoclostridium	186801|Clostridia	G	SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	SAF
DTH3_k127_9229274_8	497964.CfE428DRAFT_4944	1.573e-35	138.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DTH3_k127_9229274_0	497964.CfE428DRAFT_4943	6.187e-238	781.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
DTH3_k127_9229274_9	756272.Plabr_3146	1.878e-13	80.0	COG5492@1|root,COG5492@2|Bacteria,2IYV9@203682|Planctomycetes	203682|Planctomycetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
DTH3_k127_9229274_5	497964.CfE428DRAFT_5026	1.42e-53	199.0	2DXTF@1|root,346G5@2|Bacteria,46W16@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9229274_4	555779.Dthio_PD1816	1.078e-61	224.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,2MGTS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
DTH3_k127_9229274_3	1123508.JH636442_gene4185	3.055e-101	346.0	COG1167@1|root,COG1167@2|Bacteria,2IY9J@203682|Planctomycetes	203682|Planctomycetes	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
DTH3_k127_9229274_7	317619.ANKN01000004_gene815	2.265e-45	166.0	COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria,1MMGN@1212|Prochloraceae	1117|Cyanobacteria	FG	Alternative locus ID	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DTH3_k127_9229274_6	794903.OPIT5_16315	1.28e-47	175.0	COG1327@1|root,COG1327@2|Bacteria,46VCN@74201|Verrucomicrobia,3K7XU@414999|Opitutae	414999|Opitutae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
DTH3_k127_9229274_2	720554.Clocl_3102	7.573e-139	448.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,3WHBT@541000|Ruminococcaceae	186801|Clostridia	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
DTH3_k127_9229274_1	497964.CfE428DRAFT_4544	1.126e-155	501.0	COG0714@1|root,COG0714@2|Bacteria,46TCY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DTH3_k127_925281_2	1121440.AUMA01000016_gene183	7.1e-33	129.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WP7R@28221|Deltaproteobacteria,2MDD2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
DTH3_k127_925281_3	926569.ANT_30650	1.647e-30	123.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
DTH3_k127_925281_0	314230.DSM3645_24165	6.571e-192	610.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
DTH3_k127_925281_1	1487923.DP73_21435	9.796e-35	147.0	COG0407@1|root,COG0407@2|Bacteria,1VPBU@1239|Firmicutes,24IYJ@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_925281_4	187272.Mlg_0383	2.741e-05	48.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,1RN33@1236|Gammaproteobacteria,1WXGD@135613|Chromatiales	135613|Chromatiales	L	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
DTH3_k127_9272240_2	316067.Geob_0976	9.162e-33	133.0	28RF4@1|root,2ZDU9@2|Bacteria,1P7NC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9272240_0	478741.JAFS01000001_gene2106	4.285e-183	582.0	COG0498@1|root,COG0498@2|Bacteria,46TYU@74201|Verrucomicrobia,37G8J@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DTH3_k127_9272240_3	481448.Minf_2089	6.539e-06	57.0	COG1729@1|root,COG1729@2|Bacteria,46ZG7@74201|Verrucomicrobia,37H0Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
DTH3_k127_9272240_1	1403819.BATR01000114_gene3967	1.011e-115	377.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,2IU1R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DTH3_k127_9281936_1	485918.Cpin_7074	1.95e-37	162.0	COG3115@1|root,COG3115@2|Bacteria,4PN8V@976|Bacteroidetes,1J0PP@117747|Sphingobacteriia	976|Bacteroidetes	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9281936_0	1396141.BATP01000030_gene3715	1.049e-135	467.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
DTH3_k127_9286097_0	1166018.FAES_pFAES01098	2.168e-97	332.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,47KSB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM multicopper oxidase type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DTH3_k127_9286097_1	1077285.AGDG01000002_gene2026	3.829e-05	55.0	COG0582@1|root,COG0582@2|Bacteria,4P15N@976|Bacteroidetes,2FMSS@200643|Bacteroidia,4AKX5@815|Bacteroidaceae	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
DTH3_k127_9286717_1	314230.DSM3645_26039	3.758e-40	165.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
DTH3_k127_9286717_0	1499967.BAYZ01000159_gene538	1.355e-69	251.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DTH3_k127_9289295_1	1192034.CAP_3675	2.318e-42	163.0	2AQBM@1|root,31FHR@2|Bacteria,1QA8C@1224|Proteobacteria,434WG@68525|delta/epsilon subdivisions,2X920@28221|Deltaproteobacteria,2Z1HS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9289295_6	388467.A19Y_3953	0.0001109	47.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria,1HCZT@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DTH3_k127_9289295_2	926550.CLDAP_37740	9.235e-33	135.0	COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DTH3_k127_9289295_0	1303518.CCALI_02122	2.124e-220	724.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9289295_3	1396141.BATP01000040_gene2082	3.871e-16	93.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
DTH3_k127_9289295_4	1396141.BATP01000022_gene455	1.409e-08	68.0	COG4675@1|root,COG4675@2|Bacteria,46X85@74201|Verrucomicrobia,2IUYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
DTH3_k127_9289295_5	196490.AUEZ01000233_gene1409	1.34e-06	55.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,3JX5I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
DTH3_k127_9290995_3	497964.CfE428DRAFT_4407	5.244e-71	243.0	COG0205@1|root,COG0205@2|Bacteria	2|Bacteria	G	6-phosphofructokinase activity	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
DTH3_k127_9290995_2	530564.Psta_2284	1.985e-105	351.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DTH3_k127_9290995_4	1396141.BATP01000001_gene5330	2.672e-08	55.0	28HMZ@1|root,2Z7WD@2|Bacteria,46TFX@74201|Verrucomicrobia,2IVCD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
DTH3_k127_9290995_0	530564.Psta_1162	2.666e-290	895.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
DTH3_k127_9290995_1	1123242.JH636434_gene3592	3.868e-148	470.0	COG3957@1|root,COG3957@2|Bacteria,2IWYJ@203682|Planctomycetes	203682|Planctomycetes	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_C,XFP_N
DTH3_k127_9324719_0	411479.BACUNI_04071	3.288e-176	585.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
DTH3_k127_9328012_0	243233.MCA1632	2.057e-101	361.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XE6E@135618|Methylococcales	135618|Methylococcales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
DTH3_k127_9328012_2	1232410.KI421421_gene3334	1.964e-11	75.0	2DT2H@1|root,33IDP@2|Bacteria,1NXAG@1224|Proteobacteria,430YG@68525|delta/epsilon subdivisions,2WVZY@28221|Deltaproteobacteria,43VAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
DTH3_k127_9328012_1	686340.Metal_2200	8.079e-30	128.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9344036_0	760192.Halhy_6811	1.561e-96	321.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DTH3_k127_9344036_1	1120999.JONM01000003_gene2723	6.019e-63	220.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,2KQ5T@206351|Neisseriales	206351|Neisseriales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
DTH3_k127_9344036_4	710687.KI912270_gene983	6.737e-12	72.0	COG3011@1|root,COG3011@2|Bacteria,2HS35@201174|Actinobacteria,23ABV@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
DTH3_k127_9344036_2	314230.DSM3645_07370	5.831e-51	198.0	295WE@1|root,2ZT7B@2|Bacteria,2J2RS@203682|Planctomycetes	203682|Planctomycetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
DTH3_k127_9344036_3	240016.ABIZ01000001_gene5918	1.306e-16	89.0	2DS4P@1|root,33EH8@2|Bacteria,46XKS@74201|Verrucomicrobia,2IW5C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9356871_0	886293.Sinac_4751	1.876e-63	224.0	COG0584@1|root,COG0584@2|Bacteria,2IXVA@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DTH3_k127_9356871_1	883126.HMPREF9710_04569	1.986e-09	68.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,PI-PLC-X,Pectate_lyase22
DTH3_k127_9358769_0	556261.HMPREF0240_03665	4.082e-117	385.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24KSS@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
DTH3_k127_9358769_1	1454007.JAUG01000135_gene4079	1.093e-110	379.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IRC7@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
DTH3_k127_9365092_0	243090.RB5356	2.82e-13	76.0	COG4968@1|root,COG4968@2|Bacteria,2J4ZS@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
DTH3_k127_9365092_1	530564.Psta_1300	1.422e-06	61.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,CW_binding_2,Calx-beta,HemolysinCabind,LTD,Metallophos,Peptidase_S8
DTH3_k127_9372500_0	452637.Oter_3479	1.523e-198	621.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
DTH3_k127_9372500_3	706587.Desti_1336	2.485e-24	109.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,42VEJ@68525|delta/epsilon subdivisions,2WS0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
DTH3_k127_9372500_2	1121441.AUCX01000010_gene274	4.83e-25	116.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
DTH3_k127_9372500_1	670307.HYPDE_33213	1.549e-101	347.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
DTH3_k127_9375287_0	1396141.BATP01000003_gene5043	1.16e-133	430.0	COG1233@1|root,COG1233@2|Bacteria,46SE8@74201|Verrucomicrobia,2IVA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
DTH3_k127_9375287_6	1158292.JPOE01000002_gene3555	6.638e-12	69.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
DTH3_k127_9375287_3	240016.ABIZ01000001_gene1135	7.852e-41	155.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia,2IVXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
DTH3_k127_9375287_5	682795.AciX8_1298	1.726e-17	86.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DTH3_k127_9375287_1	1396141.BATP01000003_gene5044	1.15e-94	321.0	COG1215@1|root,COG1215@2|Bacteria,46WX3@74201|Verrucomicrobia,2IVN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DTH3_k127_9375287_4	639030.JHVA01000001_gene3731	2.963e-35	140.0	2E9V0@1|root,3340V@2|Bacteria	2|Bacteria	S	carotenoid biosynthetic process	crtO	-	-	ko:K10212	ko00906,map00906	-	R07656	RC00041	ko00000,ko00001,ko01000	-	-	-	-
DTH3_k127_9375287_2	1121937.AUHJ01000004_gene1013	3.746e-42	164.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1T7KM@1236|Gammaproteobacteria,46C37@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9375287_7	697282.Mettu_3625	0.0002964	44.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1RSMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_938229_2	497964.CfE428DRAFT_3441	5.422e-52	188.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
DTH3_k127_938229_1	497964.CfE428DRAFT_3440	3.679e-130	428.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Protein-arginine kinase	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
DTH3_k127_938229_0	1396141.BATP01000059_gene2466	0.0	1015.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
DTH3_k127_9387151_0	452637.Oter_4539	4.196e-144	464.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
DTH3_k127_9387151_1	1121481.AUAS01000005_gene2089	1.336e-21	100.0	COG2942@1|root,COG2942@2|Bacteria,4NHTQ@976|Bacteroidetes,47KVQ@768503|Cytophagia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
DTH3_k127_9403725_0	497964.CfE428DRAFT_2672	6.608e-194	616.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DTH3_k127_9403725_2	103733.JNYO01000007_gene5239	3.687e-05	57.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4E1H7@85010|Pseudonocardiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DTH3_k127_9403725_1	1291050.JAGE01000002_gene3876	1.829e-24	121.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3WIWU@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
DTH3_k127_9411409_3	926569.ANT_11850	5.984e-20	95.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
DTH3_k127_9411409_4	13035.Dacsa_0245	7.747e-17	81.0	COG1724@1|root,COG1724@2|Bacteria,1G8WI@1117|Cyanobacteria	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DTH3_k127_9411409_2	234267.Acid_7793	6.379e-24	103.0	COG1598@1|root,COG1598@2|Bacteria,3Y5U6@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9411409_0	452637.Oter_1518	2.029e-103	349.0	2BYUR@1|root,32TV8@2|Bacteria,46V5C@74201|Verrucomicrobia,3K7PA@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9416618_2	497964.CfE428DRAFT_4864	5.688e-72	248.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9416618_1	497964.CfE428DRAFT_4863	3.793e-110	380.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9416618_0	886293.Sinac_0918	1.183e-173	560.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
DTH3_k127_9424117_2	518766.Rmar_0474	2.13e-99	332.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
DTH3_k127_9424117_1	583355.Caka_0968	3.707e-140	467.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9424117_3	1353531.AZNX01000005_gene3441	2.271e-22	101.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,4BC0Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
DTH3_k127_9424117_0	404589.Anae109_3197	4.947e-172	554.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	family UPF0324	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
DTH3_k127_9424117_4	1121091.AUMP01000004_gene2392	1.707e-13	76.0	COG0842@1|root,COG0842@2|Bacteria,1UZU6@1239|Firmicutes,4HCC2@91061|Bacilli	91061|Bacilli	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DTH3_k127_9426141_3	153721.MYP_567	7.018e-15	85.0	COG3291@1|root,COG4099@1|root,COG5295@1|root,COG5297@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG5295@2|Bacteria,COG5297@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia	976|Bacteroidetes	GUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
DTH3_k127_9426141_2	1123073.KB899242_gene1109	2.379e-25	125.0	COG1470@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Haemagg_act,He_PIG,Hint_2,TIG
DTH3_k127_9426141_1	1205680.CAKO01000002_gene2136	1.756e-34	147.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_9426141_0	477641.MODMU_4803	8.289e-74	255.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4EUCR@85013|Frankiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DTH3_k127_943301_3	107636.JQNK01000002_gene261	9.97e-70	244.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2V487@28211|Alphaproteobacteria,36ZQF@31993|Methylocystaceae	28211|Alphaproteobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DTH3_k127_943301_0	518766.Rmar_2586	2.238e-128	421.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
DTH3_k127_943301_1	452637.Oter_1130	2.184e-98	333.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,3K8ZD@414999|Opitutae	414999|Opitutae	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
DTH3_k127_943301_5	237368.SCABRO_03960	4.605e-67	236.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DTH3_k127_943301_4	1123371.ATXH01000009_gene1101	6.226e-69	242.0	COG1912@1|root,COG1912@2|Bacteria,2GHAQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
DTH3_k127_943301_2	886293.Sinac_0152	1.494e-94	314.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DTH3_k127_959990_2	1090320.KB900605_gene3525	0.000768	51.0	COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,2U1SW@28211|Alphaproteobacteria,2K1C6@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
DTH3_k127_959990_1	679199.HMPREF9332_01395	5.496e-75	284.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
DTH3_k127_959990_0	497964.CfE428DRAFT_3514	3.002e-116	386.0	COG3055@1|root,COG3055@2|Bacteria,46T14@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_978510_0	1232410.KI421421_gene3328	1.016e-210	664.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DTH3_k127_978510_1	1288298.rosmuc_00470	9.236e-35	142.0	COG4238@1|root,COG4238@2|Bacteria,1RDE3@1224|Proteobacteria,2U7FF@28211|Alphaproteobacteria,46P9E@74030|Roseovarius	28211|Alphaproteobacteria	M	major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
DTH3_k127_997829_1	530564.Psta_3476	9.228e-80	282.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,NPCBM
DTH3_k127_997829_0	761193.Runsl_2769	2.832e-111	373.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
## 4460 queries scanned
## Total time (seconds): 66.82054305076599
## Rate: 66.75 q/s